5/2/2025
Last update
5/2/2025
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.3
USERS' SCORE
Questionable
Based on 26 Reviews
5.7
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Thiamin (vitamin B1) (as thiamine mononitrate)
50 mcg
4,167%
Riboflavin (vitamin B2)
50 mg
3,846%
Niacin (vitamin B3) (as niacinamide)
50 mg
313%
Vitamin B6 (as pyridoxine HCl)
50 mg
2,941%
Folate
666 mcg DFE(400 mcg folic acid)
167%
Vitamin B12 (as cyanocobalamin)
50 mcg
2,083%
Biotin (as D-biotin)
50 mcg
167%
Pantothenic Acid (vitamin B5) (as D-ca pantothenate)
50 mg
1,000%
Choline (as choline bitartrate)
21 mg
4%
Inositol
50 mg
**
Herbal Powdered Blend(kelp [plant] , acerola extract complex [fruit], alfalfa [leaf and stem], parsley [leaf], rose hips [fruit], watercress [herb])
3.5 mg
**
Top Medical Research Studies
8
We examined the impact of Niacin on anxiety and memory loss caused by aging in a rat study. Rats were grouped and treated with various doses of Niacin and D-galactose for 14 days, followed by behavioral tests to assess anxiety and memory.
Our results showed that Niacin significantly reduced anxiety-like symptoms and improved memory deficits. Additionally, it mitigated factors like oxidative stress and inflammation, enhancing brain health. Overall, Niacin's antioxidant and neuro-modulatory properties suggest it may be beneficial in addressing aging-related psychiatric issues.
Our results showed that Niacin significantly reduced anxiety-like symptoms and improved memory deficits. Additionally, it mitigated factors like oxidative stress and inflammation, enhancing brain health. Overall, Niacin's antioxidant and neuro-modulatory properties suggest it may be beneficial in addressing aging-related psychiatric issues.
Read More
We explored how vitamin B could help fight anxiety and depression linked to nicotine withdrawal in young male rats.
The study involved giving some rats nicotine before dividing them into different groups, where some were treated with vitamin B and others with bupropion—a common anxiety medication.
The results were promising, with vitamin B showing potential in reducing anxiety symptoms, comparable to bupropion. This opens the door for vitamin B as a possible new treatment option for various anxiety-related issues.
The study involved giving some rats nicotine before dividing them into different groups, where some were treated with vitamin B and others with bupropion—a common anxiety medication.
The results were promising, with vitamin B showing potential in reducing anxiety symptoms, comparable to bupropion. This opens the door for vitamin B as a possible new treatment option for various anxiety-related issues.
Read More
7
We investigated how Vitamin B can affect anxiety and depression in a rat model facing chronic stress. Seventy-two rats were divided into three groups: a control group, a stressed group, and a stressed group receiving Vitamin B injections.
The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
Read More
Most Useful Reviews
2
No effects
183 people found this helpful
After taking two tablets for over a month, I noticed no reduction in anxiety, although my urine turned bright yellow. I learned that vitamin C isn't compatible with B vitamins, which I found concerning. This complex didn’t help with my anxiety as others have.
Read More
9
Effective for anxiety
10 people found this helpful
Working complex of B vitamins! It’s gluten-free, non-GMO, and vegan. The complex is hypoallergenic and does not cause abdominal discomfort. It effectively suppresses anxiety and restlessness and works better than Combilipen. Moreover, B vitamins positively impact hair health and help normalise sleep. In summary, Solgar's B-Complex is effective and safe, deserving top marks and recommendations!
Read More
10
Reduces anxiety instantly
6 people found this helpful
I don't understand why I hadn’t tried this vitamin earlier. After just one pill, I noticed immediate improvements. Fatigue and anxiety disappeared. I always take it before PMS, and it keeps my nerves in check during stressful work. This supplement is essential for managing postpartum depression. I truly recommend it!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.3
- All Researches
8
We examined the impact of Niacin on anxiety and memory loss caused by aging in a rat study. Rats were grouped and treated with various doses of Niacin and D-galactose for 14 days, followed by behavioral tests to assess anxiety and memory.
Our results showed that Niacin significantly reduced anxiety-like symptoms and improved memory deficits. Additionally, it mitigated factors like oxidative stress and inflammation, enhancing brain health. Overall, Niacin's antioxidant and neuro-modulatory properties suggest it may be beneficial in addressing aging-related psychiatric issues.
Our results showed that Niacin significantly reduced anxiety-like symptoms and improved memory deficits. Additionally, it mitigated factors like oxidative stress and inflammation, enhancing brain health. Overall, Niacin's antioxidant and neuro-modulatory properties suggest it may be beneficial in addressing aging-related psychiatric issues.
Read More
We explored how vitamin B could help fight anxiety and depression linked to nicotine withdrawal in young male rats.
The study involved giving some rats nicotine before dividing them into different groups, where some were treated with vitamin B and others with bupropion—a common anxiety medication.
The results were promising, with vitamin B showing potential in reducing anxiety symptoms, comparable to bupropion. This opens the door for vitamin B as a possible new treatment option for various anxiety-related issues.
The study involved giving some rats nicotine before dividing them into different groups, where some were treated with vitamin B and others with bupropion—a common anxiety medication.
The results were promising, with vitamin B showing potential in reducing anxiety symptoms, comparable to bupropion. This opens the door for vitamin B as a possible new treatment option for various anxiety-related issues.
Read More
7
We investigated how Vitamin B can affect anxiety and depression in a rat model facing chronic stress. Seventy-two rats were divided into three groups: a control group, a stressed group, and a stressed group receiving Vitamin B injections.
The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
Read More
7
Vitamin B aids anxiety recovery
We explored the effects of vitamin B supplementation on anxiety and cognitive function in male Swiss albino mice following traumatic brain injury (TBI). Our research found that vitamin B appears to improve neurological impairments, enhance memory, and reduce anxiety-like behaviors.
Additionally, we saw a reduction in oxidative stress markers, indicating better neuronal health. This suggests that vitamin B not only helps with anxiety but also plays a role in recovery from cognitive dysfunctions associated with TBI.
Additionally, we saw a reduction in oxidative stress markers, indicating better neuronal health. This suggests that vitamin B not only helps with anxiety but also plays a role in recovery from cognitive dysfunctions associated with TBI.
Read More
We explored the effectiveness of vitamin B complex in treating anxiety among patients with Post-COVID-19 syndrome (PC19S) through the PreVitaCOV trial. This study involved 240 participants who were given either prednisolone, vitamin B1, B6, and B12, a combination of these treatments, or a placebo. While the trial showed high feasibility and safety, it ultimately did not demonstrate significant benefits in symptom change over placebo in anxiety or other evaluated symptoms.
Read More
User Reviews
USERS' SCORE
Questionable
Based on 26 Reviews
5.7
- All Reviews
- Positive Reviews
- Negative Reviews
2
No effects
183 people found this helpful
After taking two tablets for over a month, I noticed no reduction in anxiety, although my urine turned bright yellow. I learned that vitamin C isn't compatible with B vitamins, which I found concerning. This complex didn’t help with my anxiety as others have.
Read More
9
Effective for anxiety
10 people found this helpful
Working complex of B vitamins! It’s gluten-free, non-GMO, and vegan. The complex is hypoallergenic and does not cause abdominal discomfort. It effectively suppresses anxiety and restlessness and works better than Combilipen. Moreover, B vitamins positively impact hair health and help normalise sleep. In summary, Solgar's B-Complex is effective and safe, deserving top marks and recommendations!
Read More
10
Reduces anxiety instantly
6 people found this helpful
I don't understand why I hadn’t tried this vitamin earlier. After just one pill, I noticed immediate improvements. Fatigue and anxiety disappeared. I always take it before PMS, and it keeps my nerves in check during stressful work. This supplement is essential for managing postpartum depression. I truly recommend it!
Read More
0
Not suitable
5 people found this helpful
Unfortunately, this vitamin complex did not suit me. After taking it, I experienced shaking and worsened anxiety. My husband noticed no effects, so I switched to another B complex that was easier to digest and found relief from anxiety and improved my ferritin levels.
Read More
10
Hypoallergenic and effective
3 people found this helpful
This B-Complex dietary supplement is a magic pill for anxiety! It’s allergen-free and has no unpleasant side effects. It remarkably suppresses anxiety far better than Combilipen. It also improves complexion and promotes better sleep. Solgar’s B-Complex is effective and safe—definitely deserving of high recommendations!
Read More
Frequently Asked Questions
10
Reduces anxiety instantly
6 people found this helpful
I don't understand why I hadn’t tried this vitamin earlier. After just one pill, I noticed immediate improvements. Fatigue and anxiety disappeared. I always take it before PMS, and it keeps my nerves in check during stressful work. This supplement is essential for managing postpartum depression. I truly recommend it!
7.5
Less anxiety
We took these vitamins on a doctor's recommendation, and they work well. I noticed a significant reduction in anxiety by the third week, and my sleep improved.
9
Immediate anxiety relief
1 people found this helpful
I’ve been taking it for over a month now, and I’m enjoying reduced anxiety and migraines. The effect on my nervous system is almost instantaneous. I appreciate the good quality and taste of the product—truly energising!
2
No effects
183 people found this helpful
After taking two tablets for over a month, I noticed no reduction in anxiety, although my urine turned bright yellow. I learned that vitamin C isn't compatible with B vitamins, which I found concerning. This complex didn’t help with my anxiety as others have.
10
Energises and uplifts mood
1 people found this helpful
These vitamins are a treasure for combating stress and anxiety. They boost energy and lift my mood significantly. After taking one daily, I feel revitalised and more engaged with life. They really help reduce anxiety, although I did experience a skin rash during one course.
7.5
Calming effects
This works well for me during pre-menopause. It alleviated my anxiety and depression without needing high dosages. The 50 works perfectly with my other supplements.
7.5
Reduced anxiety
I took this on my endocrinologist's advice for AIT and hypothyroidism. I felt emotionally better, with diminished anxiety and hyperresponsibility. This complex should benefit everyone, regardless of age. Highly recommended!
9
Excellent for relaxation
1 people found this helpful
I took this as prescribed and noticed decreased anxiety and better sleep. My nervous system calmed down, panic attacks reduced, and I felt more energetic. The small capsules are easy to swallow with no distinct taste.
7
We investigated how Vitamin B can affect anxiety and depression in a rat model facing chronic stress. Seventy-two rats were divided into three groups: a control group, a stressed group, and a stressed group receiving Vitamin B injections.
The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
8
We examined the impact of Niacin on anxiety and memory loss caused by aging in a rat study. Rats were grouped and treated with various doses of Niacin and D-galactose for 14 days, followed by behavioral tests to assess anxiety and memory.
Our results showed that Niacin significantly reduced anxiety-like symptoms and improved memory deficits. Additionally, it mitigated factors like oxidative stress and inflammation, enhancing brain health. Overall, Niacin's antioxidant and neuro-modulatory properties suggest it may be beneficial in addressing aging-related psychiatric issues.
Our results showed that Niacin significantly reduced anxiety-like symptoms and improved memory deficits. Additionally, it mitigated factors like oxidative stress and inflammation, enhancing brain health. Overall, Niacin's antioxidant and neuro-modulatory properties suggest it may be beneficial in addressing aging-related psychiatric issues.
We explored the effectiveness of vitamin B complex in treating anxiety among patients with Post-COVID-19 syndrome (PC19S) through the PreVitaCOV trial. This study involved 240 participants who were given either prednisolone, vitamin B1, B6, and B12, a combination of these treatments, or a placebo. While the trial showed high feasibility and safety, it ultimately did not demonstrate significant benefits in symptom change over placebo in anxiety or other evaluated symptoms.
7
Vitamin B aids anxiety recovery
We explored the effects of vitamin B supplementation on anxiety and cognitive function in male Swiss albino mice following traumatic brain injury (TBI). Our research found that vitamin B appears to improve neurological impairments, enhance memory, and reduce anxiety-like behaviors.
Additionally, we saw a reduction in oxidative stress markers, indicating better neuronal health. This suggests that vitamin B not only helps with anxiety but also plays a role in recovery from cognitive dysfunctions associated with TBI.
Additionally, we saw a reduction in oxidative stress markers, indicating better neuronal health. This suggests that vitamin B not only helps with anxiety but also plays a role in recovery from cognitive dysfunctions associated with TBI.
We explored how vitamin B could help fight anxiety and depression linked to nicotine withdrawal in young male rats.
The study involved giving some rats nicotine before dividing them into different groups, where some were treated with vitamin B and others with bupropion—a common anxiety medication.
The results were promising, with vitamin B showing potential in reducing anxiety symptoms, comparable to bupropion. This opens the door for vitamin B as a possible new treatment option for various anxiety-related issues.
The study involved giving some rats nicotine before dividing them into different groups, where some were treated with vitamin B and others with bupropion—a common anxiety medication.
The results were promising, with vitamin B showing potential in reducing anxiety symptoms, comparable to bupropion. This opens the door for vitamin B as a possible new treatment option for various anxiety-related issues.
References
- Chen J, Liu J, Zhang P, Zhang S. [Effects of Vitamin B on Behaviors, Brain Monoamine Neurotransmitters, and Brain-Derived Neurotrophic Factor in Depressive Rats]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2025;56:206. 10.12182/20250160608
- Samad N, Hameed A, Manzoor N, Shoukat S, Irfan A, et al. Antioxidant and neuro-modulatory effects of niacin prevent D-galactose-induced behavioral deficits and memory impairment. Exp Gerontol. 2024;198:112624. 10.1016/j.exger.2024.112624
- Yadav P, Nasir F, Sivanandam TM. Neuroprotective effect of vitamin B supplementation on cognitive functions and neuronal morphology at different time intervals after traumatic brain injury in male Swiss albino mice. Neurochem Int. 2024;180:105869. 10.1016/j.neuint.2024.105869
- Tengelmann C, Joos S, Kaußner Y, Malzahn U, Lunden L, et al. Feasibility, safety and effectiveness of prednisolone and vitamin B1, B6, and B12 in patients with post-COVID-19-syndrome (PreVitaCOV) - protocol of a randomised, double-blind, placebo-controlled multicentre trial in primary care (phase IIIb). BMC Infect Dis. 2024;24:56. 10.1186/s12879-023-08925-2
- Pahlavani H, Masoudi M, Khoshroo N, Kakhki S, Mahdi Rezavanimehr M, et al. Vitamin B reversed anxiety and depression induced by adolescent nicotine withdrawal through alteration the inflammatory, oxidative and serotoninergic profiles in male rats. Biochem Pharmacol. 2023;217:115832. 10.1016/j.bcp.2023.115832
- Kakhki S, Goodarzi M, Abbaszade-Cheragheali A, Rajabi M, Masoumipour AH, et al. Folic acid supplementation improved cognitive deficits associated with lithium administration during pregnancy in rat offspring. Int J Dev Neurosci. 2023;83:615. 10.1002/jdn.10289
- Shemirani F, Titcomb TJ, Saxby SM, Eyck PT, Rubenstein LM, et al. Association of serum homocysteine, folate, and vitamin B and mood following the Swank and Wahls elimination dietary interventions in relapsing-remitting multiple sclerosis: Secondary analysis of the WAVES trial. Mult Scler Relat Disord. 2023;75:104743. 10.1016/j.msard.2023.104743
