' 
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6
USERS' SCORE
Good
Based on 1 Review
8.6
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Biotin
5,000 mcg
16,667%
Calcium (as dicalcium phosphate)
148 mg
11%
Phosphorous (as dicalcium phosphate)
115 mg
9%
Top Medical Research Studies
4
Low-dose biotin effects minimal
The clinical significance of low dose biotin supplements (<300μg/day) in the treatment of patients with hypothyroidism: crucial or overestimated?
Relevant to biotin in hypothyroidism
We set out to investigate how low-dose biotin supplements, specifically those containing less than 300μg per day, might affect thyroid hormone levels in patients with hypothyroidism. Our approach included a detailed evaluation of 57 patients who were receiving thyroxine and also taking biotin supplements for a period ranging from 10 to 60 days.
Throughout the study, we measured the levels of thyroid-stimulating hormone (TSH) and free T4 (FT4) while the patients were on biotin and again 10 days after they stopped taking the supplement. As a control, we compared these findings to those of 31 age-matched individuals who were also being treated for hypothyroidism but were not using biotin.
Our analysis suggests that any changes observed in thyroid hormone profiles due to low-dose biotin supplementation are not clinically significant. In most cases, these changes do not warrant any adjustments to the patient's thyroid medication.
Overall, while our findings contribute to understanding the relationship between biotin and thyroid hormone levels, it appears that low-dose biotin may not play a crucial role in the treatment of hypothyroidism. Larger, more comprehensive studies would be beneficial to explore this phenomenon further.
Throughout the study, we measured the levels of thyroid-stimulating hormone (TSH) and free T4 (FT4) while the patients were on biotin and again 10 days after they stopped taking the supplement. As a control, we compared these findings to those of 31 age-matched individuals who were also being treated for hypothyroidism but were not using biotin.
Our analysis suggests that any changes observed in thyroid hormone profiles due to low-dose biotin supplementation are not clinically significant. In most cases, these changes do not warrant any adjustments to the patient's thyroid medication.
Overall, while our findings contribute to understanding the relationship between biotin and thyroid hormone levels, it appears that low-dose biotin may not play a crucial role in the treatment of hypothyroidism. Larger, more comprehensive studies would be beneficial to explore this phenomenon further.
Read More
8
Biotin complicates hypothyroidism diagnosis
Delayed Diagnosis of Congenital Hypothyroidism in a Child with Trisomy 21 and Biotinidase Deficiency and Successful Use of Levothyroxine Sodium Oral Solution.
Interference impacts thyroid assessment
We examined the complex interaction between biotin treatment and thyroid function in a unique case of a child with both trisomy 21 and partial biotinidase deficiency. The study shed light on how biotin supplementation—needed for treating biotinidase deficiency—can interfere with thyroid hormone assessments. This interference led to a misleading "normal" thyroid-stimulating hormone (TSH) result early in the infant’s life, which delayed the diagnosis of congenital hypothyroidism.
After pausing biotin treatment for just four days and retesting, we discovered a significantly elevated TSH level. This prompted us to initiate treatment with levothyroxine—a common medication for hypothyroidism. Initially, we used tablet form but soon transitioned to an oral solution to address dosing challenges that arose with the tablets. Interestingly, this switch improved our ability to manage TSH levels effectively.
While this case emphasizes the importance of precise laboratory testing in the context of biotin treatment, it does not establish any direct benefit of biotin for managing hypothyroidism itself. Overall, our findings highlight the need for careful monitoring and adjustments in treatment approaches for those with additional health challenges, such as trisomy 21 and biotinidase deficiency.
After pausing biotin treatment for just four days and retesting, we discovered a significantly elevated TSH level. This prompted us to initiate treatment with levothyroxine—a common medication for hypothyroidism. Initially, we used tablet form but soon transitioned to an oral solution to address dosing challenges that arose with the tablets. Interestingly, this switch improved our ability to manage TSH levels effectively.
While this case emphasizes the importance of precise laboratory testing in the context of biotin treatment, it does not establish any direct benefit of biotin for managing hypothyroidism itself. Overall, our findings highlight the need for careful monitoring and adjustments in treatment approaches for those with additional health challenges, such as trisomy 21 and biotinidase deficiency.
Read More
Most Useful Reviews
10
Hair loss improvement
My hair stopped falling out! I have hypothyroidism and was experiencing significant hair loss, with thinning so severe that my scalp was visible and my hairline was receding. This was particularly disheartening for me as a woman. After switching to Solgar supplements, I ordered their biotin, and practically overnight, my hair stopped falling out. Previously, my brush would be full of hair, but now there are only three to five hairs after brushing. While I can't say for certain if I've regrown any hair, the fact that it has stopped falling out is a massive improvement! Additionally, my nails seem to be growing faster and are stronger now. A tip: be consistent with daily intake, and take biotin in the morning to avoid sleepless nights.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6
8
Biotin complicates hypothyroidism diagnosis
Delayed Diagnosis of Congenital Hypothyroidism in a Child with Trisomy 21 and Biotinidase Deficiency and Successful Use of Levothyroxine Sodium Oral Solution.
Interference impacts thyroid assessment
We examined the complex interaction between biotin treatment and thyroid function in a unique case of a child with both trisomy 21 and partial biotinidase deficiency. The study shed light on how biotin supplementation—needed for treating biotinidase deficiency—can interfere with thyroid hormone assessments. This interference led to a misleading "normal" thyroid-stimulating hormone (TSH) result early in the infant’s life, which delayed the diagnosis of congenital hypothyroidism.
After pausing biotin treatment for just four days and retesting, we discovered a significantly elevated TSH level. This prompted us to initiate treatment with levothyroxine—a common medication for hypothyroidism. Initially, we used tablet form but soon transitioned to an oral solution to address dosing challenges that arose with the tablets. Interestingly, this switch improved our ability to manage TSH levels effectively.
While this case emphasizes the importance of precise laboratory testing in the context of biotin treatment, it does not establish any direct benefit of biotin for managing hypothyroidism itself. Overall, our findings highlight the need for careful monitoring and adjustments in treatment approaches for those with additional health challenges, such as trisomy 21 and biotinidase deficiency.
After pausing biotin treatment for just four days and retesting, we discovered a significantly elevated TSH level. This prompted us to initiate treatment with levothyroxine—a common medication for hypothyroidism. Initially, we used tablet form but soon transitioned to an oral solution to address dosing challenges that arose with the tablets. Interestingly, this switch improved our ability to manage TSH levels effectively.
While this case emphasizes the importance of precise laboratory testing in the context of biotin treatment, it does not establish any direct benefit of biotin for managing hypothyroidism itself. Overall, our findings highlight the need for careful monitoring and adjustments in treatment approaches for those with additional health challenges, such as trisomy 21 and biotinidase deficiency.
Read More
4
Low-dose biotin effects minimal
The clinical significance of low dose biotin supplements (<300μg/day) in the treatment of patients with hypothyroidism: crucial or overestimated?
Relevant to biotin in hypothyroidism
We set out to investigate how low-dose biotin supplements, specifically those containing less than 300μg per day, might affect thyroid hormone levels in patients with hypothyroidism. Our approach included a detailed evaluation of 57 patients who were receiving thyroxine and also taking biotin supplements for a period ranging from 10 to 60 days.
Throughout the study, we measured the levels of thyroid-stimulating hormone (TSH) and free T4 (FT4) while the patients were on biotin and again 10 days after they stopped taking the supplement. As a control, we compared these findings to those of 31 age-matched individuals who were also being treated for hypothyroidism but were not using biotin.
Our analysis suggests that any changes observed in thyroid hormone profiles due to low-dose biotin supplementation are not clinically significant. In most cases, these changes do not warrant any adjustments to the patient's thyroid medication.
Overall, while our findings contribute to understanding the relationship between biotin and thyroid hormone levels, it appears that low-dose biotin may not play a crucial role in the treatment of hypothyroidism. Larger, more comprehensive studies would be beneficial to explore this phenomenon further.
Throughout the study, we measured the levels of thyroid-stimulating hormone (TSH) and free T4 (FT4) while the patients were on biotin and again 10 days after they stopped taking the supplement. As a control, we compared these findings to those of 31 age-matched individuals who were also being treated for hypothyroidism but were not using biotin.
Our analysis suggests that any changes observed in thyroid hormone profiles due to low-dose biotin supplementation are not clinically significant. In most cases, these changes do not warrant any adjustments to the patient's thyroid medication.
Overall, while our findings contribute to understanding the relationship between biotin and thyroid hormone levels, it appears that low-dose biotin may not play a crucial role in the treatment of hypothyroidism. Larger, more comprehensive studies would be beneficial to explore this phenomenon further.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.6
10
Hair loss improvement
My hair stopped falling out! I have hypothyroidism and was experiencing significant hair loss, with thinning so severe that my scalp was visible and my hairline was receding. This was particularly disheartening for me as a woman. After switching to Solgar supplements, I ordered their biotin, and practically overnight, my hair stopped falling out. Previously, my brush would be full of hair, but now there are only three to five hairs after brushing. While I can't say for certain if I've regrown any hair, the fact that it has stopped falling out is a massive improvement! Additionally, my nails seem to be growing faster and are stronger now. A tip: be consistent with daily intake, and take biotin in the morning to avoid sleepless nights.
Read More
