Last update
5/26/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 7 Reviews
8.4
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Iron (as iron bisglycinate chelate†)
25 mg
139%
Top Medical Research Studies
9
We explored the impact of iron on chemotherapy effectiveness, particularly in the treatment of osteosarcoma (OS). The study revealed promising insights into how combining iron with eriodictyol and cisplatin could promote ferroptosis—a form of regulated cell death that can improve the overall effectiveness of cancer therapies.
The researchers discovered that eriodictyol can curb a protein known as BACH1, which leads to reduced production of GPX4, a key player in protecting cells from ferroptosis. By diminishing GPX4 levels, this combination appears to push cancer cells towards ferroptosis more effectively.
Moreover, employing hollow mesoporous nanocubes to deliver eriodictyol and cisplatin seamlessly combines these agents to enhance cell death in OS. Through multiple mechanisms, including the depletion of protective molecules and the direct initiation of fatal processes in cancer cells, the nanocomplex showed impressive results in both lab tests and animal studies.
Importantly, the treatment demonstrated effectiveness without causing significant harm to other organs, hinting at its potential as a therapeutic strategy for OS patients in need of better treatment options.
The researchers discovered that eriodictyol can curb a protein known as BACH1, which leads to reduced production of GPX4, a key player in protecting cells from ferroptosis. By diminishing GPX4 levels, this combination appears to push cancer cells towards ferroptosis more effectively.
Moreover, employing hollow mesoporous nanocubes to deliver eriodictyol and cisplatin seamlessly combines these agents to enhance cell death in OS. Through multiple mechanisms, including the depletion of protective molecules and the direct initiation of fatal processes in cancer cells, the nanocomplex showed impressive results in both lab tests and animal studies.
Importantly, the treatment demonstrated effectiveness without causing significant harm to other organs, hinting at its potential as a therapeutic strategy for OS patients in need of better treatment options.
Read More
Most Useful Reviews
8
Positive recovery progress
17 people found this helpful
After the course of chemotherapy, my body felt depleted, and my hemoglobin levels were extremely low. It required numerous medications to recover, including an iron supplement recommended by my oncologist. Ordering from England was costly, so I opted for a large supply from iHerb. It was only towards the end of my treatment that my levels started to normalise, and I felt more energetic. My oncologist is pleased with my progress, attributing it to this iron supplement, as my recovery is better than expected.
Read More
10
Significant hemoglobin increase
3 people found this helpful
My mum has been taking this iron supplement since starting chemotherapy, and it's been remarkable. Her hemoglobin has risen from 95 to 130, which is impressive considering her previous levels without this product. I highly recommend it as she takes just two capsules daily.
Read More
9
No side effects experienced
After chemotherapy, I struggled with absorbing pharmaceutical iron in any form due to severe side effects. However, after three weeks of taking this supplement, I've experienced no nausea, and my digestion is normal. I've noticed that my nails and gums have improved, which is encouraging, even before retesting.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
- All Researches
9
We explored the impact of iron on chemotherapy effectiveness, particularly in the treatment of osteosarcoma (OS). The study revealed promising insights into how combining iron with eriodictyol and cisplatin could promote ferroptosis—a form of regulated cell death that can improve the overall effectiveness of cancer therapies.
The researchers discovered that eriodictyol can curb a protein known as BACH1, which leads to reduced production of GPX4, a key player in protecting cells from ferroptosis. By diminishing GPX4 levels, this combination appears to push cancer cells towards ferroptosis more effectively.
Moreover, employing hollow mesoporous nanocubes to deliver eriodictyol and cisplatin seamlessly combines these agents to enhance cell death in OS. Through multiple mechanisms, including the depletion of protective molecules and the direct initiation of fatal processes in cancer cells, the nanocomplex showed impressive results in both lab tests and animal studies.
Importantly, the treatment demonstrated effectiveness without causing significant harm to other organs, hinting at its potential as a therapeutic strategy for OS patients in need of better treatment options.
The researchers discovered that eriodictyol can curb a protein known as BACH1, which leads to reduced production of GPX4, a key player in protecting cells from ferroptosis. By diminishing GPX4 levels, this combination appears to push cancer cells towards ferroptosis more effectively.
Moreover, employing hollow mesoporous nanocubes to deliver eriodictyol and cisplatin seamlessly combines these agents to enhance cell death in OS. Through multiple mechanisms, including the depletion of protective molecules and the direct initiation of fatal processes in cancer cells, the nanocomplex showed impressive results in both lab tests and animal studies.
Importantly, the treatment demonstrated effectiveness without causing significant harm to other organs, hinting at its potential as a therapeutic strategy for OS patients in need of better treatment options.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
8
Positive recovery progress
17 people found this helpful
After the course of chemotherapy, my body felt depleted, and my hemoglobin levels were extremely low. It required numerous medications to recover, including an iron supplement recommended by my oncologist. Ordering from England was costly, so I opted for a large supply from iHerb. It was only towards the end of my treatment that my levels started to normalise, and I felt more energetic. My oncologist is pleased with my progress, attributing it to this iron supplement, as my recovery is better than expected.
Read More
10
Significant hemoglobin increase
3 people found this helpful
My mum has been taking this iron supplement since starting chemotherapy, and it's been remarkable. Her hemoglobin has risen from 95 to 130, which is impressive considering her previous levels without this product. I highly recommend it as she takes just two capsules daily.
Read More
9
No side effects experienced
After chemotherapy, I struggled with absorbing pharmaceutical iron in any form due to severe side effects. However, after three weeks of taking this supplement, I've experienced no nausea, and my digestion is normal. I've noticed that my nails and gums have improved, which is encouraging, even before retesting.
Read More
8
Maintains normal levels
This iron supplement has been excellent for helping me maintain normal hemoglobin levels while undergoing chemotherapy. I am very pleased with how it supports my health during treatment.
Read More
9
Iron levels improvement
20 people found this helpful
This product provided great absorption when paired with vitamin C. It was ordered for a cancer patient whose iron was depleted due to chemotherapy. After trying other Kosher iron supplements without success, we switched to Solgar gentle iron. Her iron levels began to rise, and she no longer requires transfusions. She took it on an empty stomach with 1000mg of vitamin C.
Read More
Frequently Asked Questions
9
No side effects experienced
After chemotherapy, I struggled with absorbing pharmaceutical iron in any form due to severe side effects. However, after three weeks of taking this supplement, I've experienced no nausea, and my digestion is normal. I've noticed that my nails and gums have improved, which is encouraging, even before retesting.
8
Positive recovery progress
17 people found this helpful
After the course of chemotherapy, my body felt depleted, and my hemoglobin levels were extremely low. It required numerous medications to recover, including an iron supplement recommended by my oncologist. Ordering from England was costly, so I opted for a large supply from iHerb. It was only towards the end of my treatment that my levels started to normalise, and I felt more energetic. My oncologist is pleased with my progress, attributing it to this iron supplement, as my recovery is better than expected.
10
Significant hemoglobin increase
3 people found this helpful
My mum has been taking this iron supplement since starting chemotherapy, and it's been remarkable. Her hemoglobin has risen from 95 to 130, which is impressive considering her previous levels without this product. I highly recommend it as she takes just two capsules daily.
8
Maintains normal levels
This iron supplement has been excellent for helping me maintain normal hemoglobin levels while undergoing chemotherapy. I am very pleased with how it supports my health during treatment.
7
Effective iron supplement
13 people found this helpful
The most effective and gentle solution for iron deficiency is iron bisglycinate. Unlike conventional medications, which may cause side effects, this form has superior absorption and tolerability. It aids in the prevention and treatment of iron deficiency, especially after chemotherapy, when my hemoglobin levels were critically low. After taking 2-3 capsules daily for two months, my hemoglobin increased significantly without side effects. This iron has become invaluable, particularly as other prescribed remedies were ineffective.
9
We explored the impact of iron on chemotherapy effectiveness, particularly in the treatment of osteosarcoma (OS). The study revealed promising insights into how combining iron with eriodictyol and cisplatin could promote ferroptosis—a form of regulated cell death that can improve the overall effectiveness of cancer therapies.
The researchers discovered that eriodictyol can curb a protein known as BACH1, which leads to reduced production of GPX4, a key player in protecting cells from ferroptosis. By diminishing GPX4 levels, this combination appears to push cancer cells towards ferroptosis more effectively.
Moreover, employing hollow mesoporous nanocubes to deliver eriodictyol and cisplatin seamlessly combines these agents to enhance cell death in OS. Through multiple mechanisms, including the depletion of protective molecules and the direct initiation of fatal processes in cancer cells, the nanocomplex showed impressive results in both lab tests and animal studies.
Importantly, the treatment demonstrated effectiveness without causing significant harm to other organs, hinting at its potential as a therapeutic strategy for OS patients in need of better treatment options.
The researchers discovered that eriodictyol can curb a protein known as BACH1, which leads to reduced production of GPX4, a key player in protecting cells from ferroptosis. By diminishing GPX4 levels, this combination appears to push cancer cells towards ferroptosis more effectively.
Moreover, employing hollow mesoporous nanocubes to deliver eriodictyol and cisplatin seamlessly combines these agents to enhance cell death in OS. Through multiple mechanisms, including the depletion of protective molecules and the direct initiation of fatal processes in cancer cells, the nanocomplex showed impressive results in both lab tests and animal studies.
Importantly, the treatment demonstrated effectiveness without causing significant harm to other organs, hinting at its potential as a therapeutic strategy for OS patients in need of better treatment options.
References
- Lin Z, Li Y, Wu Z, Liu Q, Li X, et al. Eriodictyol-cisplatin coated nanomedicine synergistically promote osteosarcoma cells ferroptosis and chemosensitivity. J Nanobiotechnology. 2025;23:109. 10.1186/s12951-025-03206-3
