Medical Researches
Questionable
Based on 3 Researches
Iron's minimal effect on constipationLow-Dose Prophylactic Oral Iron Supplementation (Ferrous Fumarate, Ferrous Bisglycinate, and Ferrous Sulphate) in Pregnancy Is Not Associated With Clinically Significant Gastrointestinal Complaints: Results From Two Randomized Studies.
Study explores iron and constipation
We explored the effects of low-dose iron supplementation on gastrointestinal complaints, particularly constipation, in pregnant women. Conducting two randomized studies, we aimed to determine how different forms of iron—ferrous fumarate, ferrous bisglycinate, and ferrous sulphate—would affect the frequency of GI issues among healthy women throughout their pregnancy.
Through our investigations, we found that constipation was only significantly associated with higher doses of ferrous fumarate (80 mg/day). Interestingly, women taking lower doses of ferrous fumarate (20-60 mg/day) did not report more GI side effects, indicating that manageable doses of iron may be tolerated without significant worry about constipation.
Among the iron formulas tested, ferrous bisglycinate at 25 mg showed the best profile, resulting in fewer GI complaints overall compared to the others. In fact, it was linked to a lower incidence of black stools, which can often be associated with iron intake. Ultimately, we observed that while low-dose iron supplementation might incur some side effects, they are generally not severe enough to warrant a change in dosage or interruption of treatment.
Read More
We carefully looked at the impact of lactoferrin (Lf) on treating iron deficiency anemia (IDA) in children, especially focusing on its connection to constipation. In an extensive review of 11 studies, including 10 randomized controlled trials, we saw promising results where children receiving Lf showed notable improvements in their hemoglobin and serum ferritin levels compared to those who only received iron or a placebo.
Interestingly, we found that while some adverse effects like constipation, vomiting, and abdominal pain were reported, those treated with Lf experienced a significant decrease in constipation. This suggests that Lf not only helps in boosting iron levels but may also be easier on the digestive system than traditional iron supplements.
Overall, our exploration indicates that incorporating lactoferrin in the treatment of IDA in children not only helps address anemia effectively but also might provide a gentler alternative for the gut. Users considering iron supplements for their children might find lactoferrin to be a beneficial option.
Read More
Iron supplementation effects on constipationEfficacy of daily versus intermittent oral iron supplementation for prevention of anaemia among pregnant women: a systematic review and meta-analysis.
Impact on constipation noted
We examined how different types of iron supplementation affect pregnant women, particularly focusing on potential constipation as a side effect. In a systematic review and meta-analysis, we gathered data from 26 studies involving nearly 4,400 participants to compare daily and intermittent iron supplementation.
Interestingly, we found that daily oral iron supplementation was associated with a higher occurrence of constipation compared to intermittent supplementation. The adjusted odds ratio for constipation was 1.95, indicating a nearly two-fold increase in risk for those taking daily iron. However, our analysis revealed that both daily and intermittent iron supplements could increase hemoglobin levels effectively, showing no significant difference in overall efficacy.
Ultimately, while daily iron supplementation led to better ferritin levels, women experienced more adverse effects such as nausea, diarrhea, and constipation. This suggests that intermittent iron supplementation could be a more favorable option, especially for those who are sensitive to the side effects associated with daily doses.
Read More
User Reviews
Good
Based on 342 Reviews
This iron supplement saved me! I was advised to take Solgar Gentle Iron when my haemoglobin was critically low. I took three capsules daily and experienced no side effects. From the first day, I felt more energetic, and after three weeks, my haemoglobin rose significantly. Ferritin also increased. I'm grateful for Solgar's quality and highly recommend it.
Read More
This is the best iron for anemia, as it doesn’t cause constipation. After trying various medications, I was advised to take Solgar's easily digestible iron. I experienced no side effects, and within a month, my haemoglobin improved significantly. I'm continuing with it.
This is an excellent product; it’s a gentle form of iron that doesn’t cause constipation. I have noticed increased energy and improved ferritin levels, and my mother was also pleased with the results.
Solgar iron is a non-constipating, easily absorbed chelated form, unlike traditional iron salts. I take a capsule daily, ensuring it is not mixed with certain beverages to maximise efficacy. My haemoglobin improves significantly with consistent use.
It helped with my chronic anaemia. In the past, I wasted money on ineffective products. After taking this for two months, my ferritin and haemoglobin improved, plus I no longer experience headaches or the exhaustion I felt earlier. I take it with vitamin C to avoid constipation.