Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.3
USERS' SCORE
Good
Based on 7 Reviews
8.2
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Cholesterol
5 mg
2%
Total Omega 3 Polyunsaturates† providing: EPA (eicosapentaenoic acid) DHA (docosahexaenoic acid)
950 mg 504 mg378 mg
*** *** ***
Top Medical Research Studies
8
We explored the impact of a high omega-3, low omega-6 diet with fish oil on men with prostate cancer under active surveillance. In a year-long study involving 100 participants, those following the omega-rich regimen showed a notable 15% decrease in the Ki-67 index, a key marker for cancer progression.
In contrast, the control group experienced an increase in this index. While the diet showed promise in slowing down potential cancer growth, no significant differences were noted in other cancer-related measurements. Our findings encourage further research on dietary strategies in prostate cancer management.
In contrast, the control group experienced an increase in this index. While the diet showed promise in slowing down potential cancer growth, no significant differences were noted in other cancer-related measurements. Our findings encourage further research on dietary strategies in prostate cancer management.
Read More
9
We explored the potential of omega-3 fatty acids in managing pancreatic cancer using a specially designed mouse model that closely mimics human disease. Our study found that a diet enriched with omega-3s significantly reduced tumor size, lung and liver metastasis, and even suggested improved survival rates when compared to controls.
Additionally, these fatty acids altered tumor composition and induced cancer cell death without hindering cell growth. Importantly, our research points to omega-3s as promising dietary interventions that could help tackle this aggressive cancer.
Additionally, these fatty acids altered tumor composition and induced cancer cell death without hindering cell growth. Importantly, our research points to omega-3s as promising dietary interventions that could help tackle this aggressive cancer.
Read More
8
Fish oil's preventive potential on cancer
We investigated how fish oil could help prevent skin cancer in mice exposed to specific carcinogens. The study included 70 Swiss albino mice divided into different groups, receiving fish oil either orally or topically, with some serving as controls.
While high doses of fish oil showed promising results, such as reduced cancer signs and decreased markers of oxidative stress, lower doses, notably 50 mg/kg/day, did not provide any benefits.
Overall, we found that fish oil has potential as a preventive treatment for skin cancer, especially at the right dosage.
While high doses of fish oil showed promising results, such as reduced cancer signs and decreased markers of oxidative stress, lower doses, notably 50 mg/kg/day, did not provide any benefits.
Overall, we found that fish oil has potential as a preventive treatment for skin cancer, especially at the right dosage.
Read More
Most Useful Reviews
7.5
Cancer cell control
3 people found this helpful
Omega-3 fatty acids significantly impact health by ensuring a correct ratio with omega-6. The typical diet skews far towards omega-6, causing issues like blood clots, hypertension, and increased cancer cell proliferation. Countries with better ratios see improved health outcomes, highlighting the importance of omega-3 in preventing cancer.
Read More
9
Cancer prevention
I began taking omega-3 after reading David Servan-Schreiber's "Antirak," which recommends it for cancer prevention due to its strong anti-inflammatory properties. I suggest reading this book for insights on omega-3's benefits.
Read More
7.5
Blood clot reduction
I recommend Solgar omega-3 for its high dosage and glass packaging, which reduces exposure to toxic metals. I take two capsules daily, which promotes blood thinning, strengthens blood vessels, and reduces cancer risks.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.3
- All Researches
9
We explored the potential of omega-3 fatty acids in managing pancreatic cancer using a specially designed mouse model that closely mimics human disease. Our study found that a diet enriched with omega-3s significantly reduced tumor size, lung and liver metastasis, and even suggested improved survival rates when compared to controls.
Additionally, these fatty acids altered tumor composition and induced cancer cell death without hindering cell growth. Importantly, our research points to omega-3s as promising dietary interventions that could help tackle this aggressive cancer.
Additionally, these fatty acids altered tumor composition and induced cancer cell death without hindering cell growth. Importantly, our research points to omega-3s as promising dietary interventions that could help tackle this aggressive cancer.
Read More
We investigated the role of alpha-linolenic acid (ALA), a plant-based omega-3 found in perilla seed oil, in preventing colitis-associated colorectal cancer (CRC) using a mouse model.
Mice were given different diets, while only the control group received soybean oil.
The results showed that those on a 5% perilla seed oil diet had fewer tumors and lower markers of inflammation compared to those on fish oil or soybean oil.
Overall, perilla seed oil appeared to help slow tumor progression and restore gut health.
Mice were given different diets, while only the control group received soybean oil.
The results showed that those on a 5% perilla seed oil diet had fewer tumors and lower markers of inflammation compared to those on fish oil or soybean oil.
Overall, perilla seed oil appeared to help slow tumor progression and restore gut health.
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8
We assessed how different types of fatty acids in red blood cells relate to the risk of esophageal cancer. Analyzing samples from 158 cancer patients and 224 controls, we found that higher levels of omega-3 fats, like DHA and EPA, were linked to a lower risk of developing this aggressive cancer. Conversely, high concentrations of certain saturated fats were associated with increased risk. Our findings suggest that the balance of fatty acids in the diet may have important implications for esophageal cancer susceptibility.
Read More
8
We examined the impact of omega-3 fish oil on chemotherapy-induced peripheral neuropathy (CIPN) in mice. Our findings indicate that this fish oil supplementation effectively prevented hypersensitivity caused by common chemotherapy drugs.
Over 30 days, it reduced neuroinflammation, which seems to be a key factor in mitigating pain and discomfort linked to treatments like paclitaxel and oxaliplatin.
By normalizing certain biochemical parameters, omega-3 fish oil holds potential to enhance the quality of life for cancer survivors facing CIPN.
Over 30 days, it reduced neuroinflammation, which seems to be a key factor in mitigating pain and discomfort linked to treatments like paclitaxel and oxaliplatin.
By normalizing certain biochemical parameters, omega-3 fish oil holds potential to enhance the quality of life for cancer survivors facing CIPN.
Read More
8
Fish oil's preventive potential on cancer
We investigated how fish oil could help prevent skin cancer in mice exposed to specific carcinogens. The study included 70 Swiss albino mice divided into different groups, receiving fish oil either orally or topically, with some serving as controls.
While high doses of fish oil showed promising results, such as reduced cancer signs and decreased markers of oxidative stress, lower doses, notably 50 mg/kg/day, did not provide any benefits.
Overall, we found that fish oil has potential as a preventive treatment for skin cancer, especially at the right dosage.
While high doses of fish oil showed promising results, such as reduced cancer signs and decreased markers of oxidative stress, lower doses, notably 50 mg/kg/day, did not provide any benefits.
Overall, we found that fish oil has potential as a preventive treatment for skin cancer, especially at the right dosage.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Cancer cell control
3 people found this helpful
Omega-3 fatty acids significantly impact health by ensuring a correct ratio with omega-6. The typical diet skews far towards omega-6, causing issues like blood clots, hypertension, and increased cancer cell proliferation. Countries with better ratios see improved health outcomes, highlighting the importance of omega-3 in preventing cancer.
Read More
9
Cancer prevention
I began taking omega-3 after reading David Servan-Schreiber's "Antirak," which recommends it for cancer prevention due to its strong anti-inflammatory properties. I suggest reading this book for insights on omega-3's benefits.
Read More
7.5
Blood clot reduction
I recommend Solgar omega-3 for its high dosage and glass packaging, which reduces exposure to toxic metals. I take two capsules daily, which promotes blood thinning, strengthens blood vessels, and reduces cancer risks.
Read More
7.5
Antioxidant properties
1 people found this helpful
My endocrinologist recommended this remedy as a powerful antioxidant that combats a variety of ailments, including high blood pressure and depression. Omega-3 is noted for its extensive benefits, including the prevention of cancer. In the USSR, fish oil was mandatory for children, which may explain the decline in health experienced today.
Read More
7.5
Breast cancer protection
Omega-3 PUFAs during pregnancy reduce the risk of premature birth, alleviate menopause symptoms, and protect against breast cancer. They also offer relief from menstrual pain.
Read More
Frequently Asked Questions
7.5
Blood clot reduction
I recommend Solgar omega-3 for its high dosage and glass packaging, which reduces exposure to toxic metals. I take two capsules daily, which promotes blood thinning, strengthens blood vessels, and reduces cancer risks.
7.5
Health improvement
Omega-3 was advised by my therapist to maintain immunity. It's crucial for the body as it can't produce these essential fatty acids. Solgar’s Omega-3 reduces cancer risk, lowers bad cholesterol, and improves overall health. My emotional state and physical appearance have notably improved.
7.5
Antioxidant properties
1 people found this helpful
My endocrinologist recommended this remedy as a powerful antioxidant that combats a variety of ailments, including high blood pressure and depression. Omega-3 is noted for its extensive benefits, including the prevention of cancer. In the USSR, fish oil was mandatory for children, which may explain the decline in health experienced today.
7.5
Cancer cell control
3 people found this helpful
Omega-3 fatty acids significantly impact health by ensuring a correct ratio with omega-6. The typical diet skews far towards omega-6, causing issues like blood clots, hypertension, and increased cancer cell proliferation. Countries with better ratios see improved health outcomes, highlighting the importance of omega-3 in preventing cancer.
8
We assessed how different types of fatty acids in red blood cells relate to the risk of esophageal cancer. Analyzing samples from 158 cancer patients and 224 controls, we found that higher levels of omega-3 fats, like DHA and EPA, were linked to a lower risk of developing this aggressive cancer. Conversely, high concentrations of certain saturated fats were associated with increased risk. Our findings suggest that the balance of fatty acids in the diet may have important implications for esophageal cancer susceptibility.
7
Omega-3s may reduce cancer risk
We examined the connection between omega-3 fatty acids in the blood and the risk of colorectal cancer among UK Biobank participants. Our analysis showed that higher levels of omega-3s were linked to a decreased risk of developing colorectal cancer, especially in males and for proximal colon cancers.
Interestingly, the relationship was nonlinear, suggesting that benefits plateau at higher omega-3 concentrations. This study could influence nutritional guidelines if our findings are supported by further research in various populations.
Interestingly, the relationship was nonlinear, suggesting that benefits plateau at higher omega-3 concentrations. This study could influence nutritional guidelines if our findings are supported by further research in various populations.
8
We examined the impact of omega-3 fish oil on chemotherapy-induced peripheral neuropathy (CIPN) in mice. Our findings indicate that this fish oil supplementation effectively prevented hypersensitivity caused by common chemotherapy drugs.
Over 30 days, it reduced neuroinflammation, which seems to be a key factor in mitigating pain and discomfort linked to treatments like paclitaxel and oxaliplatin.
By normalizing certain biochemical parameters, omega-3 fish oil holds potential to enhance the quality of life for cancer survivors facing CIPN.
Over 30 days, it reduced neuroinflammation, which seems to be a key factor in mitigating pain and discomfort linked to treatments like paclitaxel and oxaliplatin.
By normalizing certain biochemical parameters, omega-3 fish oil holds potential to enhance the quality of life for cancer survivors facing CIPN.
7
Omega-3 and Vitamin D improved nutrition
We explored the impact of omega-3 fatty acids and vitamin D on the nutrition of women recently diagnosed with breast cancer. In this open-label randomized controlled trial, 88 participants were divided into four groups to receive different combinations of omega-3 and vitamin D or act as controls.
After nine weeks, those taking omega-3, vitamin D, or both showed notable improvements in nutritional status, measured by various health assessments. This suggests that these supplements can play a significant role for women with breast cancer in enhancing their overall well-being during treatment.
After nine weeks, those taking omega-3, vitamin D, or both showed notable improvements in nutritional status, measured by various health assessments. This suggests that these supplements can play a significant role for women with breast cancer in enhancing their overall well-being during treatment.
4
We explored the relationship between omega-3 and omega-6 fatty acids and cancer risk in a large UK Biobank study with over 253,000 participants. Our analysis revealed slight inverse associations between the levels of these fatty acids and overall cancer incidence.
However, while most site-specific cancers showed similar trends, prostate cancer was an exception, demonstrating a positive association with omega-3 levels. Overall, the findings suggest that while omega-3 and omega-6 may be linked to lower cancer risks, the benefits are not universal across all cancer types.
However, while most site-specific cancers showed similar trends, prostate cancer was an exception, demonstrating a positive association with omega-3 levels. Overall, the findings suggest that while omega-3 and omega-6 may be linked to lower cancer risks, the benefits are not universal across all cancer types.
References
- Yin H, Wang Y, Chen Y, Shehzad Q, Xiao F. Association between red blood cell fatty acids composition and risk of esophageal cancer: a hospital-based case-control study. Lipids Health Dis. 2025;24:101. 10.1186/s12944-025-02531-8
- Melato J, Goldoni FC, Benvenutti L, Corrêa TP, Remor AP, et al. Omega-3-Enriched Fish oil reduces the chemotherapy-induced peripheral neuropathy in mice. Neuropharmacology. 2025;271:110384. 10.1016/j.neuropharm.2025.110384
- Cheniti H, Kadi A, Agred R, Kadi Y, Djeradi MK, et al. Fish Oil's Preventive Effect on Two-Stage Skin Carcinogenesis in Swiss Albino Mice: Involvement of NF-ҝB Pathways and Oxidative Stress in a Dose- and Route Dependent Manner. Mol Nutr Food Res. 2025;69:e202400630. 10.1002/mnfr.202400630
- van der Meij B, Parsons S, Mazurak V. The impact of n-3 polyunsaturated fatty acids in patients with cancer: emerging themes. Curr Opin Clin Nutr Metab Care. 2025;28:75. 10.1097/MCO.0000000000001102
- Garay MI, Mazo T, Ferrero V, Barotto NN, Lagares C, et al. Novel inhibitory effect of Omega-3 fatty acids regulating pancreatic cancer progression. Carcinogenesis. 2025;46. 10.1093/carcin/bgae081
- Aldoori J, Zulyniak MA, Toogood GJ, Hull MA. Plasma n-3 Polyunsaturated Fatty Acid Levels and Colorectal Cancer Risk in the UK Biobank: Evidence of Nonlinearity, as Well as Tumor Site- and Sex-Specificity. Cancer Epidemiol Biomarkers Prev. 2025;34:394. 10.1158/1055-9965.EPI-24-1154
- Pires LBC, Salaroli LB, Podesta OPG, Haraguchi FK, Lopes-Júnior LC. Omega-3 Supplementation and Nutritional Status in Patients with Pancreatic Neoplasms: A Systematic Review. Nutrients. 2024;16. 10.3390/nu16234036
- Sun G, Fuller H, Fenton H, Race AD, Downing A, et al. The Relationship Between Dietary and Supplemental omega-3 Highly Unsaturated Fatty Acid Intake, Blood and Tissue omega-3 Highly Unsaturated Fatty Acid Concentrations, and Colorectal Polyp Recurrence: A Secondary Analysis of the seAFOod Polyp Prevention Trial. J Nutr. 2025;155:549. 10.1016/j.tjnut.2024.12.004
- Aronson WJ, Grogan T, Liang P, Jardack P, Liddell AR, et al. High Omega-3, Low Omega-6 Diet With Fish Oil for Men With Prostate Cancer on Active Surveillance: The CAPFISH-3 Randomized Clinical Trial. J Clin Oncol. 2025;43:800. 10.1200/JCO.24.00608
- Korsirikoon C, Techaniyom P, Kettawan A, Rungruang T, Metheetrairut C, et al. Cold-pressed extraction of perilla seed oil enriched with alpha-linolenic acid mitigates tumour progression and restores gut microbial homeostasis in the AOM/DSS mice model of colitis-associated colorectal cancer. PLoS One. 2024;19:e0315172. 10.1371/journal.pone.0315172
- Almassri HF, Abdul Kadir A, Srour M, Foo LH. The Effects of Omega-3 Fatty Acids and Vitamin D Supplementation on the Nutritional Status of Women with Breast Cancer in Palestine: An Open-Label Randomized Controlled Trial. Nutrients. 2024;16. 10.3390/nu16223960
- Almassri HF, Abdul Kadir A, Srour M, Foo LH. The effects of Omega-3 fatty acids and vitamin D supplementation on the quality of life and blood inflammation markers in newly diagnosed breast cancer women: An open-labelled randomised controlled trial. Clin Nutr ESPEN. 2025;65:64. 10.1016/j.clnesp.2024.11.014
- Głowacka K, Ibanez S, Renoult O, Vermonden P, Giolito MV, et al. Acid-exposed and hypoxic cancer cells do not overlap but are interdependent for unsaturated fatty acid resources. Nat Commun. 2024;15:10107. 10.1038/s41467-024-54435-3
- Machuca J, Wirkus J, Ead AS, Vahmani P, Matsukuma KE, et al. Dietary ω-3 Fatty Acids Mitigate Intestinal Barrier Integrity Alterations in Mice Fed a High-Fat Diet: Implications for Pancreatic Carcinogenesis. J Nutr. 2025;155:197. 10.1016/j.tjnut.2024.10.054
- Zhang Y, Sun Y, Song S, Khankari NK, Brenna JT, et al. Associations of plasma omega-6 and omega-3 fatty acids with overall and 19 site-specific cancers: A population-based cohort study in UK Biobank. Int J Cancer. 2025;156:1154. 10.1002/ijc.35226
- Lam CS, Hua R, Loong HH, Chung VC, Cheung YT. Association between fish oil and glucosamine use and mortality in patients diagnosed with cancer: the role of the Life Essential 8 score and cancer prognosis. Nutr J. 2024;23:124. 10.1186/s12937-024-01032-1
