' 
SCIENTIFIC SCORE
Moderately Effective
Based on 23 Researches
8.3
USERS' SCORE
Good
Based on 5 Reviews
8.6
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Vitamin B12 (as cyanocobalamin)
500 mcg
20,833%
Top Medical Research Studies
9.5
Effectiveness of B12 in IGS
Severe pancytopenia at the presentation of Imerslund-Gräsbeck syndrome in a 23-month-old Italian boy.
Relevance: Rare disorder management
We explored the case of a 23-month-old boy suffering from severe pancytopenia linked to Imerslund-Gräsbeck syndrome, a rare condition caused by an inability to absorb vitamin B12. Upon diagnosis, the boy received vitamin B12 replacement therapy, which effectively addressed his symptoms and improved his health.
This case highlights the significance of early detection and treatment of IGS to avoid potential neurological damage. It's crucial to recognize this condition, even when neurological symptoms are absent, to provide timely care.
This case highlights the significance of early detection and treatment of IGS to avoid potential neurological damage. It's crucial to recognize this condition, even when neurological symptoms are absent, to provide timely care.
Read More
9.5
Oral B12 significantly improves anemia
Oral vitamin B12 supplementation in pernicious anemia: a prospective cohort study.
High relevance for B12 efficacy
We focused on how oral vitamin B12 could help those with pernicious anemia, where absorption is usually impaired. Participants diagnosed with vitamin B12 deficiency due to this condition took a daily dose of 1000 μg of oral cyanocobalamin.
Over a year, an impressive 88.5% of them no longer showed deficiency after just one month, with significant improvements in vitamin B12 levels and related biological markers. Importantly, these benefits lasted throughout the study period.
Over a year, an impressive 88.5% of them no longer showed deficiency after just one month, with significant improvements in vitamin B12 levels and related biological markers. Importantly, these benefits lasted throughout the study period.
Read More
9
B12 treatment improves anemia outcomes
Transcobalamin deficiency - a rare genetic defect in transportation of cobalamin; case report.
Highly relevant clinical findings
We explored a rare condition called Transcobalamin deficiency, which hinders vitamin B12 transport in the body. This case involved a 2-year-old boy suffering from severe anemia and frequent infections.
After genetic tests revealed a specific mutation, we administered high doses of methylcobalamin. Remarkably, the child's health significantly improved, highlighting the importance of diagnosing and treating this deficiency early to avoid serious complications.
After genetic tests revealed a specific mutation, we administered high doses of methylcobalamin. Remarkably, the child's health significantly improved, highlighting the importance of diagnosing and treating this deficiency early to avoid serious complications.
Read More
Most Useful Reviews
9.5
Anemia symptoms relieved
I didn’t consume much meat or fish, which led to some symptoms of anaemia. Since taking this vitamin B12 supplement, my symptoms have vanished. I believe this one is of high quality, as other brands didn’t have the same effect.
Read More
9.5
Boosts energy levels
Since I started taking vitamin B12, I immediately noticed its positive impact. It helps with energy levels and can alleviate symptoms of anaemia. The capsules are easy to swallow with no side effects. I feel more energetic, particularly in the colder months, making it a valuable addition to my diet.
Read More
8.8
Alleviates anemia symptoms
A lack of B12 can cause anaemia, numbness, and swelling of the extremities. Supplementation can alleviate these symptoms.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 23 Researches
8.3
- All Researches
9.5
Effectiveness of B12 in IGS
Severe pancytopenia at the presentation of Imerslund-Gräsbeck syndrome in a 23-month-old Italian boy.
Relevance: Rare disorder management
We explored the case of a 23-month-old boy suffering from severe pancytopenia linked to Imerslund-Gräsbeck syndrome, a rare condition caused by an inability to absorb vitamin B12. Upon diagnosis, the boy received vitamin B12 replacement therapy, which effectively addressed his symptoms and improved his health.
This case highlights the significance of early detection and treatment of IGS to avoid potential neurological damage. It's crucial to recognize this condition, even when neurological symptoms are absent, to provide timely care.
This case highlights the significance of early detection and treatment of IGS to avoid potential neurological damage. It's crucial to recognize this condition, even when neurological symptoms are absent, to provide timely care.
Read More
9.5
Oral B12 significantly improves anemia
Oral vitamin B12 supplementation in pernicious anemia: a prospective cohort study.
High relevance for B12 efficacy
We focused on how oral vitamin B12 could help those with pernicious anemia, where absorption is usually impaired. Participants diagnosed with vitamin B12 deficiency due to this condition took a daily dose of 1000 μg of oral cyanocobalamin.
Over a year, an impressive 88.5% of them no longer showed deficiency after just one month, with significant improvements in vitamin B12 levels and related biological markers. Importantly, these benefits lasted throughout the study period.
Over a year, an impressive 88.5% of them no longer showed deficiency after just one month, with significant improvements in vitamin B12 levels and related biological markers. Importantly, these benefits lasted throughout the study period.
Read More
9.5
Vitamin B12 aids anemia recovery
Co-existence of autoimmune polyglandular syndrome type 3b and undifferentiated connective tissue disease with subacute combined degeneration of spinal cord in children: a case report and literature review.
Moderate relevance of vitamin B12
We investigated how vitamin B12 treatment plays a role in addressing anemia in a young adolescent with complex health issues, including severe anemia, joint problems, and neurological symptoms. This individual presented with a deficiency in vitamin B12, alongside other autoimmune conditions, leading to a diagnosis of subacute combined degeneration of the spinal cord.
The patient's treatment regimen included high-dose intravenous methylprednisolone, immunoglobulin therapy, oral naproxen, and vitamin B12 supplementation, among others. We observed that the introduction of vitamin B12 into her treatment plan contributed to combating her anemia effectively. The combination of therapies, especially with vitamin B12, significantly improved her overall health and restored her quality of life.
Our findings highlight the importance of early diagnosis and prompt treatment in patients with complex autoimmune issues. Specifically, vitamin B12 emerges as a critical component in managing anemia related to such conditions. While the study is anecdotal, it reinforces the idea that vitamin B12 can be beneficial in improving anemia outcomes in similarly affected patients.
The patient's treatment regimen included high-dose intravenous methylprednisolone, immunoglobulin therapy, oral naproxen, and vitamin B12 supplementation, among others. We observed that the introduction of vitamin B12 into her treatment plan contributed to combating her anemia effectively. The combination of therapies, especially with vitamin B12, significantly improved her overall health and restored her quality of life.
Our findings highlight the importance of early diagnosis and prompt treatment in patients with complex autoimmune issues. Specifically, vitamin B12 emerges as a critical component in managing anemia related to such conditions. While the study is anecdotal, it reinforces the idea that vitamin B12 can be beneficial in improving anemia outcomes in similarly affected patients.
Read More
9
Oral B12 therapy effective in anemia
Imerslund-Gräsbeck syndrome in a child with a novel compound heterozygous mutations in the AMN gene: a case report.
Highly relevant to genetic disorders
We explored a case of a 3-year-old girl diagnosed with Imerslund-Gräsbeck syndrome, a condition that causes vitamin B12 malabsorption and leads to anemia. After identifying novel mutations in the AMN gene, we initiated long-term oral vitamin B12 therapy.
Following treatment, her blood tests showed consistent improvement, indicating that oral B12 replacement can be an effective management strategy, especially for patients who can’t tolerate injections. This case underscores the importance of genetic testing for accurate diagnoses.
Following treatment, her blood tests showed consistent improvement, indicating that oral B12 replacement can be an effective management strategy, especially for patients who can’t tolerate injections. This case underscores the importance of genetic testing for accurate diagnoses.
Read More
9
B12 treatment improves anemia outcomes
Transcobalamin deficiency - a rare genetic defect in transportation of cobalamin; case report.
Highly relevant clinical findings
We explored a rare condition called Transcobalamin deficiency, which hinders vitamin B12 transport in the body. This case involved a 2-year-old boy suffering from severe anemia and frequent infections.
After genetic tests revealed a specific mutation, we administered high doses of methylcobalamin. Remarkably, the child's health significantly improved, highlighting the importance of diagnosing and treating this deficiency early to avoid serious complications.
After genetic tests revealed a specific mutation, we administered high doses of methylcobalamin. Remarkably, the child's health significantly improved, highlighting the importance of diagnosing and treating this deficiency early to avoid serious complications.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Anemia symptoms relieved
I didn’t consume much meat or fish, which led to some symptoms of anaemia. Since taking this vitamin B12 supplement, my symptoms have vanished. I believe this one is of high quality, as other brands didn’t have the same effect.
9.5
Boosts energy levels
Since I started taking vitamin B12, I immediately noticed its positive impact. It helps with energy levels and can alleviate symptoms of anaemia. The capsules are easy to swallow with no side effects. I feel more energetic, particularly in the colder months, making it a valuable addition to my diet.
Read More
8.8
Alleviates anemia symptoms
A lack of B12 can cause anaemia, numbness, and swelling of the extremities. Supplementation can alleviate these symptoms.
8.8
Addresses chronic fatigue
Vitamin B12 is essential for red blood cell division, which ensures proper oxygen circulation and prevents anaemia. A deficiency may lead to constant fatigue and other symptoms, making B12 supplementation crucial for health.
7.5
Essential for anemia
B12 is vital for treating B12 deficiency anaemia. I prefer taking B vitamins in combination for better results.
