We investigated the potential of vitamin D3, also known as cholecalciferol, in combating cancer while addressing concerns about its toxicity at higher doses. This study focused on enhancing the effectiveness of vitamin D3 through a clever method called liposomal encapsulation, which helps minimize side effects.
We prepared liposomal vitamin D3 (VD-LP) and conducted various tests to understand its capabilities. We found that this encapsulated form not only maintained high efficiency but also demonstrated improved stability. Our analyses showed that VD-LP had strong effects against cancer cells from colorectal, breast, and prostate cancers. Remarkably, it affected gene expression in immune cells, boosting elements that help fight infections and support the body's defenses.
Notably, VD-LP did a great job slowing tumor growth in mice and improved their survival rates without causing adverse effects like hypercalcemia, which is often a concern with regular vitamin D3 use. This evidence indicates that liposomal encapsulation of vitamin D3 could offer an effective cancer treatment strategy while minimizing unwanted side effects.
We believe this may pave the way for further research and clinical applications, showcasing vitamin D3 as a valuable addition to cancer therapy.
Read More
9
Vitamin D3 derivatives improve cancer treatment
Synthetic Studies on Vitamin D Derivatives with Diverse but Selective Biological Activities.
We focused on how modified forms of vitamin D3 can positively affect cancer treatment. The study revealed that a specific derivative, known as MART-10, demonstrated significant anti-tumor effects in mouse models. When administered at low doses, this compound showed robust anti-cancer activity against BxpC-3 cancer cells.
Additionally, we explored a new vitamin D analog, AH-1, which was found to enhance bone formation without the usual side effects associated with vitamin D treatments. This is particularly promising for osteoporosis patients. Another derivative named NS-74c even exhibited potent antagonist activity against the vitamin D receptor, indicating a potential for varied therapeutic uses.
Overall, our research highlighted the potential of vitamin D3 derivatives to tackle cancer while minimizing adverse effects. This approach opens new doors for therapeutic options in oncology, providing a glimpse into how modified vitamin D can improve treatment outcomes for patients.
Read More
8
Vitamin D's potential in CRC
Exploration and Identification of Vitamin D and Related Genes as Potential Biomarkers for Colorectal Tumors.
We delved into the intriguing relationship between vitamin D and colorectal cancer (CRC) to uncover how this nutrient might influence cancer development and treatment. The study involved measuring the serum levels of active vitamin D (1,25(OH)D) in different groups, including those with normal conditions, colorectal adenomas (CRA), and colorectal cancer (CRC).
Our findings highlighted a significant drop in vitamin D levels in CRC patients, with levels falling to 19.00 µg/mL compared to 42.99 µg/mL in normal individuals. Additionally, we conducted bioinformatics analysis to pinpoint genes linked to vitamin D and colorectal cancer, testing these using HCT116 and HT29 cell lines.
We observed that vitamin D can inhibit the growth and spread of colon cancer cells, leading to a reduction in the activity of certain cancer-promoting genes. Interestingly, our analysis also showed that a diagnostic model based on five key vitamin D-related genes exhibited high diagnostic efficiency. This reveals vitamin D's potential as a supportive approach for CRC diagnosis and treatment, offering hope for improved cancer management.
Read More
Most Useful Reviews
9
Effective for bone density
4 people found this helpful
This product is great! It's easy to swallow and has no aftertaste. Due to lower bone density from radiation treatment for cancer, I take these alongside calcium supplements, ensuring my Vitamin D intake stays healthy.
Read More
9
Stronger immunity
1 people found this helpful
Vitamin D3 is essential for immunity and bone health, particularly during pandemics. A three-month course improved my energy and mood after I discovered my low levels. This reliable product from Solgar enhances calcium absorption, vascular health, and reduces the risk of cancer. I wholeheartedly recommend it to everyone.
Read More
7.5
Cancer prevention
8 people found this helpful
Taking vitamin D3 is vital to avoid upper respiratory infections and several diseases, including cancer. Regular use can significantly improve health outcomes. Smaller capsules make it easy to integrate into my routine.
We explored the potential of vitamin D-based micelles designed to deliver paclitaxel, a key chemotherapy drug, specifically for pancreatic cancer treatment. This study focuses on developing enzyme-responsive micelles that not only carry paclitaxel but also utilize vitamin D as an integral part of the delivery system.
The micelles are made by combining vitamin D with polyethylene glycol, resulting in tiny structures that can release their drug load when interacting with enzymes typically found in pancreatic cancer cells. We observed that these micelles showed promising results in laboratory settings, enhancing the effectiveness of paclitaxel against aggressive pancreatic cancer cells compared to using paclitaxel alone.
Moreover, we noted that the vitamin D in the micelles may play a dual role: serving as both a hydrophobic core for drug delivery and a contributor to synergetic therapeutic effects. Our findings suggest that leveraging vitamin D in this way could increase the efficacy of existing treatment options for pancreatic cancer patients, which is particularly significant given the challenges currently faced in treating this disease.
Read More
9
Vitamin D3 derivatives improve cancer treatment
Synthetic Studies on Vitamin D Derivatives with Diverse but Selective Biological Activities.
We focused on how modified forms of vitamin D3 can positively affect cancer treatment. The study revealed that a specific derivative, known as MART-10, demonstrated significant anti-tumor effects in mouse models. When administered at low doses, this compound showed robust anti-cancer activity against BxpC-3 cancer cells.
Additionally, we explored a new vitamin D analog, AH-1, which was found to enhance bone formation without the usual side effects associated with vitamin D treatments. This is particularly promising for osteoporosis patients. Another derivative named NS-74c even exhibited potent antagonist activity against the vitamin D receptor, indicating a potential for varied therapeutic uses.
Overall, our research highlighted the potential of vitamin D3 derivatives to tackle cancer while minimizing adverse effects. This approach opens new doors for therapeutic options in oncology, providing a glimpse into how modified vitamin D can improve treatment outcomes for patients.
Read More
8
Vitamin D analogs in prostate cancer
[New insights of vitamin D-based therapy for prostate cancer].
We explored the potential benefits of a vitamin D analog in treating prostate cancer, which is a major cause of cancer-related deaths among men. Our work focused on understanding how this vitamin D form impacts cancer resistance and the tumor microenvironment. We used the Pten mouse model to observe the therapeutic effects of the vitamin D analog.
One significant finding was that combining this vitamin D analog with the chemotherapy drug docetaxel could overcome resistance seen in some prostate cancer cases. This combination showed promising results in primary cancer spheroids and xenografts from a patient whose cancer had resisted both docetaxel and androgen deprivation therapy.
These insights suggest that vitamin D analogs might offer new and effective strategies for managing advanced prostate cancer, particularly for those patients who have not responded well to standard treatments.
Read More
8
Vitamin D3 offers anti-cancer benefits
Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth.
We investigated the potential of vitamin D3, also known as cholecalciferol, in combating cancer while addressing concerns about its toxicity at higher doses. This study focused on enhancing the effectiveness of vitamin D3 through a clever method called liposomal encapsulation, which helps minimize side effects.
We prepared liposomal vitamin D3 (VD-LP) and conducted various tests to understand its capabilities. We found that this encapsulated form not only maintained high efficiency but also demonstrated improved stability. Our analyses showed that VD-LP had strong effects against cancer cells from colorectal, breast, and prostate cancers. Remarkably, it affected gene expression in immune cells, boosting elements that help fight infections and support the body's defenses.
Notably, VD-LP did a great job slowing tumor growth in mice and improved their survival rates without causing adverse effects like hypercalcemia, which is often a concern with regular vitamin D3 use. This evidence indicates that liposomal encapsulation of vitamin D3 could offer an effective cancer treatment strategy while minimizing unwanted side effects.
We believe this may pave the way for further research and clinical applications, showcasing vitamin D3 as a valuable addition to cancer therapy.
Read More
8
Vitamin D's potential in CRC
Exploration and Identification of Vitamin D and Related Genes as Potential Biomarkers for Colorectal Tumors.
We delved into the intriguing relationship between vitamin D and colorectal cancer (CRC) to uncover how this nutrient might influence cancer development and treatment. The study involved measuring the serum levels of active vitamin D (1,25(OH)D) in different groups, including those with normal conditions, colorectal adenomas (CRA), and colorectal cancer (CRC).
Our findings highlighted a significant drop in vitamin D levels in CRC patients, with levels falling to 19.00 µg/mL compared to 42.99 µg/mL in normal individuals. Additionally, we conducted bioinformatics analysis to pinpoint genes linked to vitamin D and colorectal cancer, testing these using HCT116 and HT29 cell lines.
We observed that vitamin D can inhibit the growth and spread of colon cancer cells, leading to a reduction in the activity of certain cancer-promoting genes. Interestingly, our analysis also showed that a diagnostic model based on five key vitamin D-related genes exhibited high diagnostic efficiency. This reveals vitamin D's potential as a supportive approach for CRC diagnosis and treatment, offering hope for improved cancer management.
This product is great! It's easy to swallow and has no aftertaste. Due to lower bone density from radiation treatment for cancer, I take these alongside calcium supplements, ensuring my Vitamin D intake stays healthy.
Read More
9
Stronger immunity
1 people found this helpful
Vitamin D3 is essential for immunity and bone health, particularly during pandemics. A three-month course improved my energy and mood after I discovered my low levels. This reliable product from Solgar enhances calcium absorption, vascular health, and reduces the risk of cancer. I wholeheartedly recommend it to everyone.
Read More
7.5
Cancer prevention
8 people found this helpful
Taking vitamin D3 is vital to avoid upper respiratory infections and several diseases, including cancer. Regular use can significantly improve health outcomes. Smaller capsules make it easy to integrate into my routine.
Read More
7.5
Improved immunity
6 people found this helpful
I regularly take vitamin D3 from Solgar, particularly during the autumn-winter period. A blood test revealed my levels were significantly low. This vitamin promotes bone health, immunity, and overall well-being. After normalising my vitamin D levels, I noticed improvements in my sleep and the condition of my hair and nails. I recommend this vitamin to everyone as a preventative measure.
Read More
7.5
Promotes health
6 people found this helpful
Like D3, it can prevent serious illnesses, including cancer. The ease of swallowing the small tablets makes them convenient. Combining with fatty foods aids absorption. I maintain a regular dosage for optimal health benefits.
Cancer is a complex group of diseases characterized by uncontrolled growth and spread of abnormal cells in the body. These cells can form tumors, invade nearby tissues, and metastasize to other parts of the body via the bloodstream or lymphatic system. While cancer can affect nearly any part of the body, it is classified into various types, including carcinomas, sarcomas, leukemia, and lymphomas, each originating from different types of cells. Risk factors for developing cancer can include genetic predisposition, lifestyle choices such as smoking and diet, environmental exposures, and certain infections.
Diagnosis typically involves medical imaging, biopsies, and a thorough review of personal and family health histories. Treatment options vary widely depending on the type and stage of cancer and may include surgery, chemotherapy, radiation therapy, immunotherapy, and targeted therapies. Early detection is crucial and can significantly improve treatment outcomes, leading to better survival rates. As awareness and research continue to advance, new methods for prevention, detection, and treatment of cancer are consistently being developed, offering hope to those affected by this challenging disease.
Vitamin D is a fat-soluble vitamin that's essential for maintaining healthy bones and teeth, supporting immune system function, and facilitating normal cell growth and development. It plays a crucial role in calcium absorption in the gut, which is vital for bone health. Unlike most vitamins, our bodies can produce Vitamin D when exposed to sunlight, specifically UVB rays, which is why it’s often referred to as the "sunshine vitamin." However, depending on your geographical location, lifestyle, and skin type, getting sufficient Vitamin D from the sun alone can be challenging, particularly during the winter months.
In addition to sunlight, Vitamin D can be obtained from certain foods such as fatty fish (like salmon and mackerel), fish liver oils, and fortified foods like milk and cereals. Some individuals may also consider supplements, especially if they're at risk for deficiency. Insufficient vitamin D levels are linked to various health issues, including rickets in children, osteomalacia in adults, and even an increased risk of chronic diseases. Regularly checking your vitamin D levels and consulting with a healthcare professional can help ensure you're meeting your needs for optimal health.
While there is ongoing research into the role of vitamin D in cancer prevention and treatment, the findings remain inconclusive. Some studies suggest that adequate levels of vitamin D may be associated with a lower risk of certain cancers, such as colorectal cancer and breast cancer, potentially due to its role in regulating cell growth and differentiation. However, definitive evidence proving that vitamin D supplements can prevent or successfully treat cancer is still lacking.
It’s important to approach the idea of using vitamin D as a cancer treatment with caution. Current guidelines recommend obtaining vitamin D primarily through safe sun exposure and diet. If you’re considering vitamin D supplementation, particularly for cancer-related purposes, it’s crucial to consult with a healthcare provider. They can provide personalized advice based on individual health needs and the latest research, ensuring that any approach to cancer management is both safe and effective.
Based on user reviews, the timeline for seeing results from taking vitamin D3 when dealing with serious health issues such as cancer may vary significantly among individuals. Users often report noticeable improvements after a period ranging from one month to three months of consistent use. For instance, one user mentioned that after a three-month course, they experienced increased energy and improved mood after addressing their low vitamin D levels Read Review. Another user highlighted that normalizing their vitamin D levels led to better sleep and improved overall well-being, indicating that results may continue to improve as levels are optimized Read Review.
Overall, while some users might notice benefits sooner, it is generally recommended to maintain regular dosing over a couple of months for optimal results. Regularly monitoring your vitamin D levels through blood tests could also aid in understanding how the supplement is impacting your health Read Review.
Scientific research reveals promising findings regarding the role of vitamin D in cancer treatment and prevention, particularly in relation to various cancer types. For instance, a study indicated that a vitamin D analog could enhance the effectiveness of chemotherapy in prostate cancer by overcoming treatment resistance, especially when combined with the drug docetaxel [1]. Furthermore, observational research has shown that lower vitamin D levels might be linked to an increased risk of breast cancer, suggesting that supplementation could serve as a preventive measure [2].
Additionally, several studies have explored the therapeutic potential of enhanced formulations of vitamin D, such as liposomal encapsulation, which has shown effectiveness against colorectal, breast, and prostate cancers without significant side effects [5]. Other investigations pointed toward vitamin D's mechanisms that inhibit growth in colon cancer cells and contribute to immune responses against aggressive tumors like glioblastoma [10]. These collective findings support the notion that vitamin D may play a vital role in cancer management, but further research, including well-designed clinical trials, is essential to establish definitive conclusions on its efficacy.
Based on user reviews, many individuals have reported a range of improvements in their symptoms after incorporating vitamin D3 into their routines. Notably, several users experienced enhanced energy levels and mood stabilization after addressing their vitamin D deficiencies. One user mentioned that after a three-month course of vitamin D3, they saw improvements in both energy and mood, highlighting its impact on overall vitality Read Review. Another user noted that normalizing their vitamin D levels led to better sleep and improvements in the condition of their hair and nails, aligning with the comprehensive health benefits often associated with adequate vitamin D intake Read Review.
Additionally, a number of users emphasized the role of vitamin D3 in bolstering immunity and potentially reducing the risk of serious diseases, including respiratory infections and cancer Read Review. Regular users have attested to the importance of maintaining consistent vitamin D levels, suggesting that while individual results can vary, a continuous regimen often leads to noticeable health benefits. It is generally recommended to consume vitamin D3 with fatty foods to aid absorption, further empowering users in their quest for improved health Read Review.
Based on user reviews, many individuals have reported positive experiences when combining vitamin D3 with other supplements in their efforts to handle cancer. A notable number of users emphasized the importance of vitamin C and zinc alongside vitamin D, as they believe these combinations are critical for managing overall health and providing immunity support during illness Read Review. Users found that maintaining adequate levels of these vitamins can potentially help prevent serious health issues, including cancer, by enhancing immune function and protecting against infections Read Review.
Moreover, some users expressed the significance of ensuring that vitamin D3 is taken with fatty foods to aid absorption, further enhancing its effectiveness Read Review. Regular use of vitamin D3, possibly in conjunction with other supplements, appears to be a common approach among users looking to optimize their health outcomes, particularly in the context of cancer prevention and management Read Review. Overall, while user experiences may vary, many regard this combination of supplements as beneficial for strengthening immunity and overall well-being.
Based on user reviews, many individuals emphasize the importance of maintaining optimal levels of Vitamin D for health benefits, particularly concerning cancer prevention. Several reviewers reported that taking Vitamin D3 regularly improved their overall well-being, noting its potential protective effects against serious illnesses, including cancer Read Review. Users also highlighted the role of Vitamin D in enhancing immunity and promoting bone health Read Review.
Additionally, some individuals mentioned the significance of dosage and timing for optimal effectiveness. One reviewer pointed out that combining Vitamin D with fatty foods aids absorption, which can enhance its health benefits Read Review. Moreover, there were indications that higher doses may lead to increased energy levels and reduced symptoms for some users, suggesting a correlation between dosage and positive health outcomes Read Review. Overall, while precise dosing recommendations were not specified, there is a consensus on the necessity of regular Vitamin D intake for cancer risk reduction and overall health enhancements.
9
Stronger immunity
1 people found this helpful
Vitamin D3 is essential for immunity and bone health, particularly during pandemics. A three-month course improved my energy and mood after I discovered my low levels. This reliable product from Solgar enhances calcium absorption, vascular health, and reduces the risk of cancer. I wholeheartedly recommend it to everyone.
7.5
Improved immunity
6 people found this helpful
I regularly take vitamin D3 from Solgar, particularly during the autumn-winter period. A blood test revealed my levels were significantly low. This vitamin promotes bone health, immunity, and overall well-being. After normalising my vitamin D levels, I noticed improvements in my sleep and the condition of my hair and nails. I recommend this vitamin to everyone as a preventative measure.
7.5
Cancer prevention
8 people found this helpful
Taking vitamin D3 is vital to avoid upper respiratory infections and several diseases, including cancer. Regular use can significantly improve health outcomes. Smaller capsules make it easy to integrate into my routine.
7.5
Cancer reduction
I take vitamin D3 regularly, especially during the pandemic, as it’s associated with a reduced risk of several serious conditions, including cancer. The tablets are easy to swallow, and I ensure they are consumed with fatty foods for better absorption.
9
Preventive measure
Vitamin D, alongside vitamin C and zinc, is critical in managing health during colds and preventing various serious health issues, including cancer. Maintaining optimal levels protects against infections and supports overall immune function.
7.5
Promotes health
6 people found this helpful
Like D3, it can prevent serious illnesses, including cancer. The ease of swallowing the small tablets makes them convenient. Combining with fatty foods aids absorption. I maintain a regular dosage for optimal health benefits.
7.5
Hormonal effects
Vitamin D is unique as it acts like a hormone. My energy levels increased, and symptoms diminished when I took higher doses. This nutrient is crucial as deficiency links to various conditions, including cancer. Optimising vitamin D intake is vital for health.
8
Vitamin D analogs in prostate cancer
[New insights of vitamin D-based therapy for prostate cancer].
We explored the potential benefits of a vitamin D analog in treating prostate cancer, which is a major cause of cancer-related deaths among men. Our work focused on understanding how this vitamin D form impacts cancer resistance and the tumor microenvironment. We used the Pten mouse model to observe the therapeutic effects of the vitamin D analog.
One significant finding was that combining this vitamin D analog with the chemotherapy drug docetaxel could overcome resistance seen in some prostate cancer cases. This combination showed promising results in primary cancer spheroids and xenografts from a patient whose cancer had resisted both docetaxel and androgen deprivation therapy.
These insights suggest that vitamin D analogs might offer new and effective strategies for managing advanced prostate cancer, particularly for those patients who have not responded well to standard treatments.
5
Vitamin D's role in breast disease
Levels of Serum 25-Hydroxy Vitamin D in Benign and Malignant Breast Disease Patients: An Observational Study.
We conducted an observational study to examine the levels of vitamin D in female patients with benign and malignant breast diseases. The research aimed to determine if there is a significant difference in vitamin D levels between those with non-cancerous conditions and those diagnosed with breast cancer.
During the study, we analyzed adult female patients admitted to a surgical department. Importantly, we excluded those who had taken vitamin D supplements recently or who had prior vitamin D deficiencies. By measuring serum vitamin D levels through a specific testing method, we were able to gather meaningful data about their relationship to breast health.
Our findings indicated a notable difference in average vitamin D levels when comparing the two groups. This suggests that inadequate vitamin D could be linked to an increased risk of developing breast cancer. Therefore, we explored the potential benefits of vitamin D supplementation as a preventive measure against breast cancer—though we acknowledge that larger and more controlled studies are essential to draw firm conclusions.
At the same time, we recognize that vitamin D has effects beyond bone health, and it is crucial to consider these broader impacts when discussing its role in cancer risk.
7
Vitamin D3 contributes to cancer treatment
Curcumin and vitamin D3 release from calcium phosphate enhances bone regeneration.
We explored the potential of vitamin D3 as part of a treatment combination with curcumin, examining its effects on human osteosarcoma cells. The study involved using calcium phosphate materials loaded with both curcumin and vitamin D3, which were then tested in a specific 3D-printed format designed to promote bone health.
Our observations indicated that as part of this combination, vitamin D3 plays a supportive role. We found that using these loaded materials improved the survival of bone-forming cells (osteoblasts) over an 11-day period. Additionally, the combination treatment significantly increased new bone formation when compared to control groups.
However, it's important to note that the study's focus on the dual impact of curcumin and vitamin D3 limits our ability to assess the isolated effects of vitamin D3 alone. The results showed a decrease in the proliferation of osteosarcoma cells, highlighting the potential anti-cancer properties of the treatment combination. Yet, these findings suggest that while vitamin D3 contributes positively, more research is needed to fully understand its effectiveness on its own.
8
Vitamin D3 enhances glioma treatment
Enhanced Antiglioma Effect by a Vitamin D3-Inserted Lipid Hybrid Neutrophil Membrane Biomimetic Multimodal Nanoplatform.
We developed an innovative treatment approach using a special type of nanoplatform that combines vitamin D3 with neutrophil membranes and chemotherapy medication doxorubicin. This platform was specifically designed to target glioblastoma, which is known as one of the most aggressive and challenging brain cancers.
Not only did we find that this treatment method was effective in delivering chemotherapy and promoting cell death in tumor cells, but we also observed that it significantly boosted the immune response against cancer. The combination activated a specific immune pathway, leading to increased production of important signaling molecules that can help fight tumors. This resulted in a shift from an immune-resistant environment to one more responsive to treatment, encouraging immune cells to attack the cancer more effectively.
Overall, the use of vitamin D3 in this multimodal strategy shows great promise for enhancing cancer therapy, opening the door for further exploration into its potential for improving glioma treatment outcomes and possibly developing more effective immune therapies.
References
Len-Tayon K, Metzger D, Laverny G. [New insights of vitamin D-based therapy for prostate cancer]. Med Sci (Paris). 2025;41:154. doi:10.1051/medsci/2025011
Soni D, Tiwari A, Kushwah PS, Dubey S, Khan S. Levels of Serum 25-Hydroxy Vitamin D in Benign and Malignant Breast Disease Patients: An Observational Study. Cureus. 2025;17:e78283. doi:10.7759/cureus.78283
Peixoto D, Ravasco JM, Blanco-Fernandez B, Veiga F, Concheiro A, et al. Enzyme-responsive vitamin D-based micelles for paclitaxel-controlled delivery and synergistic pancreatic cancer therapy. Mater Today Bio. 2025;31:101555. doi:10.1016/j.mtbio.2025.101555
Xu N, Lin H, Ding X, Wang P, Lin JM. Isotope tracing-assisted chip-based solid-phase extraction mass spectrometry for monitoring metabolic changes and vitamin D3 regulation in cells. Talanta. 2025;288:127754. doi:10.1016/j.talanta.2025.127754
Jo Y, Kushram P, Bose S. Curcumin and vitamin D3 release from calcium phosphate enhances bone regeneration. Biomater Sci. 2025. doi:10.1039/d4bm01188k
Ezcurra-Hualde M, Zalba S, Bella Á, Arrizabalaga L, Risson A, et al. Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Front Immunol. 2025;16:1529007. doi:10.3389/fimmu.2025.1529007
Wang L, Xu R, Wang M, Wang M, Su S, et al. Exploration and Identification of Vitamin D and Related Genes as Potential Biomarkers for Colorectal Tumors. Onco Targets Ther. 2025;18:129. doi:10.2147/OTT.S495066
Evans H, Greenhough A, Perry L, Lasanta G, Gonzalez CM, et al. Hypoxia Compromises the Differentiation of Human Osteosarcoma Cells to CAR-R, a Hydroxylated Derivative of Lithocholic Acid and Potent Agonist of the Vitamin D Receptor. Int J Mol Sci. 2025;26. doi:10.3390/ijms26010365
Kittaka A. Synthetic Studies on Vitamin D Derivatives with Diverse but Selective Biological Activities. Chem Pharm Bull (Tokyo). 2025;73:1. doi:10.1248/cpb.c24-00598
He W, Lv W, Liu L, Gong Y, Song K, et al. Enhanced Antiglioma Effect by a Vitamin D3-Inserted Lipid Hybrid Neutrophil Membrane Biomimetic Multimodal Nanoplatform. ACS Nano. 2024;18:35559. doi:10.1021/acsnano.4c13470
Almassri HF, Abdul Kadir A, Srour M, Foo LH. The Effects of Omega-3 Fatty Acids and Vitamin D Supplementation on the Nutritional Status of Women with Breast Cancer in Palestine: An Open-Label Randomized Controlled Trial. Nutrients. 2024;16. doi:10.3390/nu16223960
Maturana-Ramiìrez A, Aitken-Saavedra J, Rojas-Zúñiga G, Rojas-Alcayaga G, Espinoza-Santander I, et al. Hypovitaminosis D in patients with oral squamous cell carcinoma: Is a risk factor of developing this neoplasia?. Med Oral Patol Oral Cir Bucal. 2025;30:e24. doi:10.4317/medoral.26692
Almassri HF, Abdul Kadir A, Srour M, Foo LH. The effects of Omega-3 fatty acids and vitamin D supplementation on the quality of life and blood inflammation markers in newly diagnosed breast cancer women: An open-labelled randomised controlled trial. Clin Nutr ESPEN. 2025;65:64. doi:10.1016/j.clnesp.2024.11.014
García-Martínez JM, Chocarro-Calvo A, Martínez-Useros J, Regueira-Acebedo N, Fernández-Aceñero MJ, et al. SIRT1 Mediates the Antagonism of Wnt/β-Catenin Pathway by Vitamin D in Colon Carcinoma Cells. Int J Biol Sci. 2024;20:5495. doi:10.7150/ijbs.95875