Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 39 Researches
7.7
USERS' SCORE
Moderately Good
Based on 53 Reviews
7.7
Supplement Facts
Serving Size:  1 Veg Capsule
Amount Per Serving
%DV
Blend of 10 Strains of Probiotic Bacteria: Lactobacillus acidophilus (La-14), Bifidobacterium lactis (Bl-04),Lactobacillus plantarum (Lp-115), Lactobacillus casei (Lc-11),Lactobacillus rhamnosus (Lr-32), Lactobacillus paracasei (Lpc-37),Bifidobacterium breve (Bb-03), Streptococcus thermophilus (St-21),Lactobacillus salivarius (Ls-33), Bifidobacterium longum (BI-05)
100 Billion CFU
*

Top Medical Research Studies

9
Bifidobacterium lactis alleviates bloating
We conducted a study to see if a fermented dairy product with Bifidobacterium lactis DN-173 010 could help reduce bloating in patients with irritable bowel syndrome (IBS) and constipation. In a controlled trial with 34 participants over four weeks, we found that this probiotic significantly decreased abdominal girth and improved gastrointestinal transit times.

Patients reported feeling less bloated, and symptom severity also decreased. These findings suggest that fostering faster transit times may be an effective method to combat abdominal distension.
Read More
9
Lactobacillus improves bloating symptoms
We conducted a double-blind, placebo-controlled trial to assess how Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 affect bloating in patients with functional bowel disorders.

Over eight weeks, patients reported a noticeable improvement in abdominal bloating when taking probiotics compared to those on a placebo.

Notably, results showed significant relief at four weeks and continued improvement by eight weeks, especially among those with irritable bowel syndrome. This suggests probiotics could be beneficial in managing bloating symptoms.
Read More
9
Lactobacillus acidophilus reduces bloating
We examined how Lactobacillus acidophilus can help treat bloating in patients with dyspepsia due to imbalances in gut bacteria. In a study involving 30 participants, symptoms such as pain, pressure, and bloating were self-reported while objective measures like bowel movements and weight changes were also tracked.

Those affected by antibiotic-induced dysbiosis experienced rapid relief within days. Improvements were noted in symptoms of maldigestion over a week, and remarkable results were observed in patients with radiation enterocolitis. Overall, this probiotic showed promise for alleviating digestive discomfort without notable side effects.
Read More

Most Useful Reviews

9
Gut issues resolved
11 people found this helpful
This is by far the best probiotic I've taken. Unlike previous probiotics, this one has effectively cleared up my stomach issues and significantly reduced my bloating. I also noticed an improvement in my skin, which looks brighter. Although it’s a bit pricey, it's worth it if you have gut problems.
Read More
0
Stopped usage
6 people found this helpful
I experienced abdominal pain, bloating, and severe fatigue after taking this product, leading me to stop after the first pill. Even ten days post-discontinuation, I still have bloating and abdominal pain.
Read More
9
Constipation resolved
5 people found this helpful
This is one of the best probiotics available, made from high-quality ingredients. After considerable use, I felt a marked difference in my gut, with reduced bloating and more effectively absorbed nutrients. I wholeheartedly recommend it.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 39 Researches
7.7
  • All Researches
9
Lactobacillus improves bloating symptoms
We conducted a double-blind, placebo-controlled trial to assess how Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 affect bloating in patients with functional bowel disorders.

Over eight weeks, patients reported a noticeable improvement in abdominal bloating when taking probiotics compared to those on a placebo.

Notably, results showed significant relief at four weeks and continued improvement by eight weeks, especially among those with irritable bowel syndrome. This suggests probiotics could be beneficial in managing bloating symptoms.
Read More
9
SCM-III improves IBS symptoms
We conducted a study examining the effects of a novel symbiotic treatment, SCM-III, on patients with irritable bowel syndrome (IBS). Sixty-eight adults were divided into two groups—one received SCM-III and the other a heat-inactivated version, both for 12 weeks.

Our findings showed that most patients reported significant improvements in bloating and abdominal pain compared to a control group. Over 80% felt the treatment was effective, while less than 5% labelled it ineffective.

Overall, this suggests that certain IBS patients could greatly benefit from symbiotic treatments like SCM-III, though it may require a cyclic use for best results.
Read More
9
Lactobacillus acidophilus reduces bloating
We examined how Lactobacillus acidophilus can help treat bloating in patients with dyspepsia due to imbalances in gut bacteria. In a study involving 30 participants, symptoms such as pain, pressure, and bloating were self-reported while objective measures like bowel movements and weight changes were also tracked.

Those affected by antibiotic-induced dysbiosis experienced rapid relief within days. Improvements were noted in symptoms of maldigestion over a week, and remarkable results were observed in patients with radiation enterocolitis. Overall, this probiotic showed promise for alleviating digestive discomfort without notable side effects.
Read More
9
Probiotics improve allergy symptoms
We evaluated the effects of a combined probiotic treatment on food allergies in children aged 4 to 5. In our study, 92 children participated, where one group took probiotics containing Lactobacillus rhamnosus GG for 21 days, while the other group did not.

The children on probiotics experienced significant improvements in skin and gastrointestinal symptoms, including a decrease in bloating. Their IgE levels also dropped notably, suggesting an overall healthier immune response. The control group showed no significant changes.

Overall, lactobacillus rhamnosus proved beneficial for reducing allergy symptoms and improving gut health.
Read More
We investigated how a combination of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001, along with vitamin B6, affects bloating in patients with irritable bowel syndrome (IBS). In a well-structured crossover trial involving 25 IBS patients, we found that this formula significantly reduced bloating by about 36% compared to a placebo. Additionally, patients experienced reduced abdominal pain and improved gut health. Overall, this treatment shows promise for alleviating IBS symptoms and enhancing gut health.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 53 Reviews
7.7
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Gut issues resolved
11 people found this helpful
This is by far the best probiotic I've taken. Unlike previous probiotics, this one has effectively cleared up my stomach issues and significantly reduced my bloating. I also noticed an improvement in my skin, which looks brighter. Although it’s a bit pricey, it's worth it if you have gut problems.
Read More
0
Stopped usage
6 people found this helpful
I experienced abdominal pain, bloating, and severe fatigue after taking this product, leading me to stop after the first pill. Even ten days post-discontinuation, I still have bloating and abdominal pain.
Read More
9
Constipation resolved
5 people found this helpful
This is one of the best probiotics available, made from high-quality ingredients. After considerable use, I felt a marked difference in my gut, with reduced bloating and more effectively absorbed nutrients. I wholeheartedly recommend it.
Read More
9
Candida relief
4 people found this helpful
Balanced Gut! This product helps with candida and extreme bloating. It has been a significant help!
Read More
9
Bloating improved
3 people found this helpful
After using this product regularly, my colon disorder and bloating resolved. I am grateful that my stomach has returned to normal.
Read More

Frequently Asked Questions

9
Bloating relief
2 people found this helpful
An excellent probiotic. I've ordered it multiple times. It significantly alleviates my gut issues and bloating within a week of intake, making food easier to digest. Nutrition plays a role too; otherwise, no probiotic will be effective.
9
Bloating improvement
Just great! This is the best probiotic I’ve tried, with a very good combination of bacteria types and quantities. One capsule at night is effective; within days, I noticed improvements in intestinal function, and bloating disappeared. Highly recommend!
2
No improvement noted
I am not satisfied. I finished half of the can and saw only a slight difference. I felt that my bloating had decreased and the gas subsided.
9
Bloating improved
3 people found this helpful
After using this product regularly, my colon disorder and bloating resolved. I am grateful that my stomach has returned to normal.
9
Digestive improvement
1 people found this helpful
I trust the NOW company for probiotics. Alongside taking this, I also consume plantain fibre and pectin to nourish the new bacteria. I've noticed improved stool consistency, better digestion, and no bloating.
0
Stopped usage
6 people found this helpful
I experienced abdominal pain, bloating, and severe fatigue after taking this product, leading me to stop after the first pill. Even ten days post-discontinuation, I still have bloating and abdominal pain.
9
Eliminated bloating
This probiotic is excellent! It’s easy to use with just one capsule daily. It has eliminated bloating and improved my gastrointestinal function.
4
Lactobacillus acidophilus reduces flatus
We used a rigorous clinical trial to investigate the impact of Lactobacillus acidophilus on bloating and other IBS symptoms. Involving 80 patients diagnosed with IBS, we followed a double-blind, placebo-controlled approach over eight weeks.

While the treatment did not significantly relieve abdominal pain, we noted a marked decrease in flatus and overall symptom scores at eight weeks. This suggests that while lactobacillus acidophilus may not help with all IBS symptoms, it could be beneficial for reducing bloating-related discomfort.
8
Probiotics alleviate bloating in IBS
We examined how multispecies probiotics, including Lactobacillus acidophilus, affect bloating in individuals with irritable bowel syndrome (IBS). In a randomized, double-blind trial, 49 IBS patients were split into two groups: one received probiotics and the other a placebo for four weeks.

By the end of the study, we found that 68% of the probiotics group reported significant relief from IBS symptoms, including reduced bloating. Fecal analysis indicated beneficial changes in gut bacteria from the probiotics, highlighting their potential role in improving IBS symptoms.
8
Lactobacillus reduces bloating effectively
We investigated how Lactobacillus acidophilus affects bloating in patients following Roux-en-Y gastric bypass surgery. In a randomized, double-blind, placebo-controlled trial, patients received either probiotic supplements or placebo for 90 days. While both groups experienced similar rates of small intestine bacterial overgrowth (SIBO), those in the probiotic group reported significantly less bloating. They also noted increased abdominal pain initially, but that decreased over time, along with more episodes of soft stools and nausea. Hence, probiotics effectively reduce bloating without impacting SIBO levels.
7
Synbiotic improves gastrointestinal comfort
This randomized, double-blind study tested the effects of a synbiotic supplement featuring Lactobacillus acidophilus on gut health in 36 healthy adults. Over six weeks, participants taking the synbiotic reported improved gastrointestinal well-being and bowel habits compared to those who received a placebo.

While there were notable benefits in symptoms like bloating and digestive discomfort, immunological parameters did not show significant changes. This suggests that while the synbiotic could enhance gut comfort, its effects on inflammation levels appear limited.
9
Lactobacillus improves bloating symptoms
We conducted a double-blind, placebo-controlled trial to assess how Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 affect bloating in patients with functional bowel disorders.

Over eight weeks, patients reported a noticeable improvement in abdominal bloating when taking probiotics compared to those on a placebo.

Notably, results showed significant relief at four weeks and continued improvement by eight weeks, especially among those with irritable bowel syndrome. This suggests probiotics could be beneficial in managing bloating symptoms.
We investigated how a combination of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001, along with vitamin B6, affects bloating in patients with irritable bowel syndrome (IBS). In a well-structured crossover trial involving 25 IBS patients, we found that this formula significantly reduced bloating by about 36% compared to a placebo. Additionally, patients experienced reduced abdominal pain and improved gut health. Overall, this treatment shows promise for alleviating IBS symptoms and enhancing gut health.

References

  1. Xie P, Luo M, Deng X, Fan J, Xiong L. Outcome-Specific Efficacy of Different Probiotic Strains and Mixtures in Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis. Nutrients. 2023;15. 10.3390/nu15173856
  2. Wagner NRF, Ramos MRZ, de Oliveira Carlos L, da Cruz MRR, Taconeli CA, et al. Effects of Probiotics Supplementation on Gastrointestinal Symptoms and SIBO after Roux-en-Y Gastric Bypass: a Prospective, Randomized, Double-Blind, Placebo-Controlled Trial. Obes Surg. 2021;31:143. 10.1007/s11695-020-04900-x
  3. Maixent JM, Pons O, Sennoune SR, Sadrin S. Clinical effects of Lactobacillus strains as probiotics in the treatment of irritable bowel syndrome. Results from the LAPIBSS trial: Future objectives. Cell Mol Biol (Noisy-le-grand). 2020;66:211.
  4. Sadrin S, Sennoune S, Gout B, Marque S, Moreau J, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis. 2020;52:534. 10.1016/j.dld.2019.12.009
  5. Wang MC, Zaydi AI, Lin WH, Lin JS, Liong MT, et al. Putative Probiotic Strains Isolated from Kefir Improve Gastrointestinal Health Parameters in Adults: a Randomized, Single-Blind, Placebo-Controlled Study. Probiotics Antimicrob Proteins. 2020;12:840. 10.1007/s12602-019-09615-9
  6. Airaksinen K, Yeung N, Lyra A, Lahtinen SJ, Huttunen T, et al. The effect of a probiotic blend on gastrointestinal symptoms in constipated patients: a double blind, randomised, placebo controlled 2-week trial. Benef Microbes. 2019;10:617. 10.3920/BM2018.0163
  7. Georgescu D, Ancusa OE, Georgescu LA, Ionita I, Reisz D. Nonmotor gastrointestinal disorders in older patients with Parkinson's disease: is there hope?. Clin Interv Aging. 2016;11:1601.
  8. Ringel-Kulka T, Goldsmith JR, Carroll IM, Barros SP, Palsson O, et al. Lactobacillus acidophilus NCFM affects colonic mucosal opioid receptor expression in patients with functional abdominal pain - a randomised clinical study. Aliment Pharmacol Ther. 2014;40:200. 10.1111/apt.12800
  9. Yoon JS, Sohn W, Lee OY, Lee SP, Lee KN, et al. Effect of multispecies probiotics on irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. J Gastroenterol Hepatol. 2014;29:52. 10.1111/jgh.12322
  10. Andresen V, Layer P, Menge D, Keller J. [Efficacy of freeze-dried Lactobacilli in functional diarrhoe: a pilot study]. Dtsch Med Wochenschr. 2012;137:1792. 10.1055/s-0032-1305295
  11. Ringel-Kulka T, Palsson OS, Maier D, Carroll I, Galanko JA, et al. Probiotic bacteria Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 versus placebo for the symptoms of bloating in patients with functional bowel disorders: a double-blind study. J Clin Gastroenterol. 2011;45:518. 10.1097/MCG.0b013e31820ca4d6
  12. Nova E, Viadel B, Wärnberg J, Carreres JE, Marcos A. Beneficial effects of a synbiotic supplement on self-perceived gastrointestinal well-being and immunoinflammatory status of healthy adults. J Med Food. 2011;14:79. 10.1089/jmf.2008.0328
  13. Tsuchiya J, Barreto R, Okura R, Kawakita S, Fesce E, et al. Single-blind follow-up study on the effectiveness of a symbiotic preparation in irritable bowel syndrome. Chin J Dig Dis. 2004;5:169.
  14. Molin G. Probiotics in foods not containing milk or milk constituents, with special reference to Lactobacillus plantarum 299v. Am J Clin Nutr. 2001;73:380S. 10.1093/ajcn/73.2.380s
  15. Gaón D, Doweck Y, Gómez Zavaglia A, Ruiz Holgado A, Oliver G. [Lactose digestion by milk fermented with Lactobacillus acidophilus and Lactobacillus casei of human origin]. Medicina (B Aires). 1995;55:237.
  16. Kocián J. [Lactobacilli in the treatment of dyspepsia due to dysmicrobia of various causes]. Vnitr Lek. 1994;40:79.
  17. Kwon H, Nam EH, Kim H, Jo H, Bang WY, et al. Effect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial. Sci Rep. 2024;14:22384. 10.1038/s41598-024-72887-x
  18. Vorobieva OA, Shih EV, Drozdov VN, Shikh NV. [The results of the use of a combined probiotic ( and spp. ВB-12) in children with gastrointestinal and skin manifestations of food allergy]. Vopr Pitan. 2023;92:79. 10.33029/0042-8833-2023-92-3-79-86
  19. Bonfrate L, Di Palo DM, Celano G, Albert A, Vitellio P, et al. Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients. Eur J Clin Invest. 2020;50:e13201. 10.1111/eci.13201
  20. Lai HH, Chiu CH, Kong MS, Chang CJ, Chen CC. Probiotic : Effective for Managing Childhood Diarrhea by Altering Gut Microbiota and Attenuating Fecal Inflammatory Markers. Nutrients. 2019;11. 10.3390/nu11051150
  21. Vitellio P, Celano G, Bonfrate L, Gobbetti M, Portincasa P, et al. Effects of and on Gut Microbiota in Patients with Lactose Intolerance and Persisting Functional Gastrointestinal Symptoms: A Randomised, Double-Blind, Cross-Over Study. Nutrients. 2019;11. 10.3390/nu11040886
  22. Hayes SR, Vargas AJ. Probiotics for the Prevention of Pediatric Antibiotic-Associated Diarrhea. Explore (NY). 2016;12:463. 10.1016/j.explore.2016.08.015
  23. Goldenberg JZ, Lytvyn L, Steurich J, Parkin P, Mahant S, et al. Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database Syst Rev. 2015. 10.1002/14651858.CD004827.pub4
  24. Hauser G, Salkic N, Vukelic K, JajacKnez A, Stimac D. Probiotics for standard triple Helicobacter pylori eradication: a randomized, double-blind, placebo-controlled trial. Medicine (Baltimore). 2015;94:e685. 10.1097/MD.0000000000000685
  25. Tanashat M, Abuelazm M, Abouzid M, Al-Ajlouni YA, Ramadan A, et al. Efficacy of probiotics regimens for Helicobacter pylori eradication: A systematic review, pairwise, and network meta-analysis of randomized controlled trials. Clin Nutr ESPEN. 2025;65:424. 10.1016/j.clnesp.2024.11.016
  26. Srivastava S, Basak U, Naghibi M, Vijayakumar V, Parihar R, et al. A randomized double-blind, placebo-controlled trial to evaluate the safety and efficacy of live CECT 7347 (ES1) and heat-treated CECT 7347 (HT-ES1) in participants with diarrhea-predominant irritable bowel syndrome. Gut Microbes. 2024;16:2338322. 10.1080/19490976.2024.2338322
  27. Lenoir M, Wienke J, Fardao-Beyler F, Roese N. An 8-Week Course of Bifidobacterium longum 35624 Is Associated with a Reduction in the Symptoms of Irritable Bowel Syndrome. Probiotics Antimicrob Proteins. 2025;17:315. 10.1007/s12602-023-10151-w
  28. Miyoshi M, Kadoguchi H, Usami M, Hori Y. Synbiotics Improved Stool Form via Changes in the Microbiota and Short-Chain Fatty Acids in Hemodialysis Patients. Kobe J Med Sci. 2021;67:E112.
  29. Zhang C, Jiang J, Tian F, Zhao J, Zhang H, et al. Meta-analysis of randomized controlled trials of the effects of probiotics on functional constipation in adults. Clin Nutr. 2020;39:2960. 10.1016/j.clnu.2020.01.005
  30. Chen JC, Lee WJ, Tsou JJ, Liu TP, Tsai PL. Effect of probiotics on postoperative quality of gastric bypass surgeries: a prospective randomized trial. Surg Obes Relat Dis. 2016;12:57. 10.1016/j.soard.2015.07.010
  31. Colecchia A, Vestito A, La Rocca A, Pasqui F, Nikiforaki A, et al. Effect of a symbiotic preparation on the clinical manifestations of irritable bowel syndrome, constipation-variant. Results of an open, uncontrolled multicenter study. Minerva Gastroenterol Dietol. 2006;52:349.
  32. Lan W, Yang H, Zhong Z, Luo C, Huang Q, et al. subsp. LPL-RH improves postoperative gastrointestinal symptoms and nutrition indexes by regulating the gut microbiota in patients with valvular heart disease: a randomized controlled trial. Food Funct. 2024;15:7605. 10.1039/d4fo01471e
  33. Şahin K, Şahintürk Y, Köker G, Özçelik Köker G, Bostan F, et al. Metformin with Versus without Concomitant Probiotic Therapy in Newly Diagnosed Patients with Type 2 Diabetes or Prediabetes: A Comparative Analysis in Relation to Glycemic Control, Gastrointestinal Side Effects, and Treatment Compliance. Turk J Gastroenterol. 2022;33:925. 10.5152/tjg.2022.211063
  34. Shin CM, Choi YJ, Lee DH, Moon JS, Kim TY, et al. Validity and safety of ID-JPL934 in lower gastrointestinal symptom improvement. Sci Rep. 2021;11:13046. 10.1038/s41598-021-92007-3
  35. Marteau P, Le Nevé B, Quinquis L, Pichon C, Whorwell PJ, et al. Consumption of a Fermented Milk Product Containing CNCM I-2494 in Women Complaining of Minor Digestive Symptoms: Rapid Response Which Is Independent of Dietary Fibre Intake or Physical Activity. Nutrients. 2019;11. 10.3390/nu11010092
  36. Baştürk A, Artan R, Yılmaz A. Efficacy of synbiotic, probiotic, and prebiotic treatments for irritable bowel syndrome in children: A randomized controlled trial. Turk J Gastroenterol. 2016;27:439. 10.5152/tjg.2016.16301
  37. Del Piano M, Carmagnola S, Anderloni A, Andorno S, Ballarè M, et al. The use of probiotics in healthy volunteers with evacuation disorders and hard stools: a double-blind, randomized, placebo-controlled study. J Clin Gastroenterol. 2010;44 Suppl 1:S30. 10.1097/MCG.0b013e3181ee31c3
  38. Agrawal A, Houghton LA, Morris J, Reilly B, Guyonnet D, et al. Clinical trial: the effects of a fermented milk product containing Bifidobacterium lactis DN-173 010 on abdominal distension and gastrointestinal transit in irritable bowel syndrome with constipation. Aliment Pharmacol Ther. 2009;29:104. 10.1111/j.1365-2036.2008.03853.x
  39. Guyonnet D, Chassany O, Ducrotte P, Picard C, Mouret M, et al. Effect of a fermented milk containing Bifidobacterium animalis DN-173 010 on the health-related quality of life and symptoms in irritable bowel syndrome in adults in primary care: a multicentre, randomized, double-blind, controlled trial. Aliment Pharmacol Ther. 2007;26:475.
image