Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.4
USERS' SCORE
Good
Based on 6 Reviews
8.3
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Blend of 10 Strains of Probiotic Bacteria: Lactobacillus acidophilus (La-14), Bifidobacterium lactis (Bl-04),Lactobacillus plantarum (Lp-115), Lactobacillus casei (Lc-11),Lactobacillus rhamnosus (Lr-32), Lactobacillus paracasei (Lpc-37),Bifidobacterium breve (Bb-03), Streptococcus thermophilus (St-21),Lactobacillus salivarius (Ls-33), Bifidobacterium longum (BI-05)
100 Billion CFU
*
Top Medical Research Studies
9
We examined a promising new probiotic preparation designed to break down gluten and assist people with celiac disease. Our study included a randomized double-blind placebo-controlled trial with 70 volunteers over a 42-day period, where participants consumed increasing amounts of gluten following a gluten-free diet.
Those who took the probiotics showed significantly lower levels of residual gluten in their feces compared to the placebo group. Additionally, the probiotics appeared to enhance gut microbiota health, promoting beneficial microbial communities. However, despite these findings, we must proceed cautiously, as the overall impact on celiac disease management remains to be fully determined.
Those who took the probiotics showed significantly lower levels of residual gluten in their feces compared to the placebo group. Additionally, the probiotics appeared to enhance gut microbiota health, promoting beneficial microbial communities. However, despite these findings, we must proceed cautiously, as the overall impact on celiac disease management remains to be fully determined.
Read More
9
We explored the effects of Bacillus subtilis LZU-GM, a probiotic isolated from traditional Pakistani sourdough, on gluten-related issues in celiac disease. Remarkably, this strain degraded 73.7% of gluten in lab tests and showed threefold more gluten breakdown in mice models compared to untreated groups.
However, while it improved gut health by promoting beneficial bacteria, and reducing inflammatory markers, it didn't eliminate the formation of antibodies associated with gluten sensitivity. Thus, we found that although LZU-GM has potential, it may not be a complete solution for managing celiac disease.
However, while it improved gut health by promoting beneficial bacteria, and reducing inflammatory markers, it didn't eliminate the formation of antibodies associated with gluten sensitivity. Thus, we found that although LZU-GM has potential, it may not be a complete solution for managing celiac disease.
Read More
8
Probiotic shows potential in celiac
We explored whether Acetobacter ghanensis could reduce gliadin-induced toxicity in intestinal cells from celiac disease patients. Using a cell culture model, we found that gliadin disrupts the intestinal barrier and raises inflammatory markers like IL-6 and TNFα. However, when A. ghanensis was introduced, it showed potential in restoring barrier function and digesting gluten peptides. This study highlights A. ghanensis as a promising candidate for improving gut health in those affected by celiac disease, although more research is needed to confirm these findings.
Read More
Most Useful Reviews
7.5
Reduced stomach issues
1 people found this helpful
Best lifestyle change! My boyfriend, who has celiac disease and minor stomach ulcers, has experienced less bloating since he started using this product. It helps him digest food better and lowers his chances of suffering from stomach aches.
Read More
7.5
Best probiotic ever
8 people found this helpful
Very good, I have celiac disease and have had it for over 22 years. Occasionally, I need to resort to a course of probiotics, and at present, this is the best I've ever tried.
Read More
9
Reduced symptoms
3 people found this helpful
Works for me! I suffer from IBS and gluten intolerance, as well as anxiety. All these issues have significantly improved since I began using this probiotic, and it's very reasonably priced too.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.4
- All Researches
9
We examined a promising new probiotic preparation designed to break down gluten and assist people with celiac disease. Our study included a randomized double-blind placebo-controlled trial with 70 volunteers over a 42-day period, where participants consumed increasing amounts of gluten following a gluten-free diet.
Those who took the probiotics showed significantly lower levels of residual gluten in their feces compared to the placebo group. Additionally, the probiotics appeared to enhance gut microbiota health, promoting beneficial microbial communities. However, despite these findings, we must proceed cautiously, as the overall impact on celiac disease management remains to be fully determined.
Those who took the probiotics showed significantly lower levels of residual gluten in their feces compared to the placebo group. Additionally, the probiotics appeared to enhance gut microbiota health, promoting beneficial microbial communities. However, despite these findings, we must proceed cautiously, as the overall impact on celiac disease management remains to be fully determined.
Read More
9
We explored the effects of Bacillus subtilis LZU-GM, a probiotic isolated from traditional Pakistani sourdough, on gluten-related issues in celiac disease. Remarkably, this strain degraded 73.7% of gluten in lab tests and showed threefold more gluten breakdown in mice models compared to untreated groups.
However, while it improved gut health by promoting beneficial bacteria, and reducing inflammatory markers, it didn't eliminate the formation of antibodies associated with gluten sensitivity. Thus, we found that although LZU-GM has potential, it may not be a complete solution for managing celiac disease.
However, while it improved gut health by promoting beneficial bacteria, and reducing inflammatory markers, it didn't eliminate the formation of antibodies associated with gluten sensitivity. Thus, we found that although LZU-GM has potential, it may not be a complete solution for managing celiac disease.
Read More
8
Brazilian cassava cultivars enhance probiotics
We examined the prebiotic effects of Brazilian cassava cultivars on celiac individuals. Focusing on two selected varieties, OUR and UPI, we observed their ability to promote growth in beneficial probiotic strains. This was evident in the increased population of helpful bacteria compared to established prebiotics like fructooligosaccharides. Our findings indicate that these cassava cultivars can positively influence the gut microbiota in celiacs, suggesting their potential use as prebiotic ingredients in functional foods and supplements.
Read More
8
Probiotic shows potential in celiac
We explored whether Acetobacter ghanensis could reduce gliadin-induced toxicity in intestinal cells from celiac disease patients. Using a cell culture model, we found that gliadin disrupts the intestinal barrier and raises inflammatory markers like IL-6 and TNFα. However, when A. ghanensis was introduced, it showed potential in restoring barrier function and digesting gluten peptides. This study highlights A. ghanensis as a promising candidate for improving gut health in those affected by celiac disease, although more research is needed to confirm these findings.
Read More
8
We investigated the effectiveness of the NLS super strain (NLS-SS) probiotic on alleviating gastrointestinal symptoms in patients with celiac disease (CD) who have been on a gluten-free diet for at least two years. Through a carefully designed randomized, double-blind, placebo-controlled trial, we found that those with severe symptoms experienced improved relief from their CD symptoms after taking NLS-SS.
This probiotic also influenced gut microbiota diversity in these patients without significant side effects. While promising, more extensive studies are necessary to fully validate these results.
This probiotic also influenced gut microbiota diversity in these patients without significant side effects. While promising, more extensive studies are necessary to fully validate these results.
Read More
User Reviews
USERS' SCORE
Good
Based on 6 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Reduced stomach issues
1 people found this helpful
Best lifestyle change! My boyfriend, who has celiac disease and minor stomach ulcers, has experienced less bloating since he started using this product. It helps him digest food better and lowers his chances of suffering from stomach aches.
Read More
7.5
Best probiotic ever
8 people found this helpful
Very good, I have celiac disease and have had it for over 22 years. Occasionally, I need to resort to a course of probiotics, and at present, this is the best I've ever tried.
Read More
9
Reduced symptoms
3 people found this helpful
Works for me! I suffer from IBS and gluten intolerance, as well as anxiety. All these issues have significantly improved since I began using this probiotic, and it's very reasonably priced too.
Read More
9
Best vegan option
2 people found this helpful
This is an actual vegan probiotic! Finding a quality vegan probiotic supplement with genuine gluten-free ingredients can be tough. This one, boasting 100 billion CFU, is exceptionally effective and valuable, especially considering it aids my delicate digestive system during my recovery from hospitalised anorexia.
Read More
7.5
Improved digestion
This product is excellent, designed to promote digestive and immune health. It contains various probiotic strains, including Lactobacillus acidophilus. Ever since I adopted a whole food plant-based diet, it has greatly improved my digestion, alleviating bloating and other gastrointestinal symptoms while also enhancing my skin health.
Read More
Frequently Asked Questions
7.5
Reduced stomach issues
1 people found this helpful
Best lifestyle change! My boyfriend, who has celiac disease and minor stomach ulcers, has experienced less bloating since he started using this product. It helps him digest food better and lowers his chances of suffering from stomach aches.
7.5
Strengthened microbiota
1 people found this helpful
Following a microbiota test, I realised I had several deficiencies in probiotics. After taking this powerful formula for nearly a year, I noticed a significant reduction in my gastrointestinal issues, allowing me to gradually reintroduce previously restricted foods. However, patience is crucial, as a weakened stomach and intestines take time to recover.
9
Reduced symptoms
3 people found this helpful
Works for me! I suffer from IBS and gluten intolerance, as well as anxiety. All these issues have significantly improved since I began using this probiotic, and it's very reasonably priced too.
7.5
Improved digestion
This product is excellent, designed to promote digestive and immune health. It contains various probiotic strains, including Lactobacillus acidophilus. Ever since I adopted a whole food plant-based diet, it has greatly improved my digestion, alleviating bloating and other gastrointestinal symptoms while also enhancing my skin health.
7.5
Best probiotic ever
8 people found this helpful
Very good, I have celiac disease and have had it for over 22 years. Occasionally, I need to resort to a course of probiotics, and at present, this is the best I've ever tried.
9
Best vegan option
2 people found this helpful
This is an actual vegan probiotic! Finding a quality vegan probiotic supplement with genuine gluten-free ingredients can be tough. This one, boasting 100 billion CFU, is exceptionally effective and valuable, especially considering it aids my delicate digestive system during my recovery from hospitalised anorexia.
9
We examined a promising new probiotic preparation designed to break down gluten and assist people with celiac disease. Our study included a randomized double-blind placebo-controlled trial with 70 volunteers over a 42-day period, where participants consumed increasing amounts of gluten following a gluten-free diet.
Those who took the probiotics showed significantly lower levels of residual gluten in their feces compared to the placebo group. Additionally, the probiotics appeared to enhance gut microbiota health, promoting beneficial microbial communities. However, despite these findings, we must proceed cautiously, as the overall impact on celiac disease management remains to be fully determined.
Those who took the probiotics showed significantly lower levels of residual gluten in their feces compared to the placebo group. Additionally, the probiotics appeared to enhance gut microbiota health, promoting beneficial microbial communities. However, despite these findings, we must proceed cautiously, as the overall impact on celiac disease management remains to be fully determined.
9
We explored the effects of Bacillus subtilis LZU-GM, a probiotic isolated from traditional Pakistani sourdough, on gluten-related issues in celiac disease. Remarkably, this strain degraded 73.7% of gluten in lab tests and showed threefold more gluten breakdown in mice models compared to untreated groups.
However, while it improved gut health by promoting beneficial bacteria, and reducing inflammatory markers, it didn't eliminate the formation of antibodies associated with gluten sensitivity. Thus, we found that although LZU-GM has potential, it may not be a complete solution for managing celiac disease.
However, while it improved gut health by promoting beneficial bacteria, and reducing inflammatory markers, it didn't eliminate the formation of antibodies associated with gluten sensitivity. Thus, we found that although LZU-GM has potential, it may not be a complete solution for managing celiac disease.
7
Probiotics show potential benefits
We assessed the potential benefits of probiotics for managing gastrointestinal symptoms in patients with celiac disease (CD). After analyzing data from 14 clinical trials, we found that probiotics may help reduce GI symptoms, especially in those with severe cases, and promote a better immune response.
The analysis also indicated that probiotics increased levels of beneficial gut bacteria, such as Bifidobacterium and Lactobacillus, without raising adverse effects compared to placebos.
However, the evidence remains inconclusive, highlighting the need for further quality studies to determine the best probiotic combinations.
The analysis also indicated that probiotics increased levels of beneficial gut bacteria, such as Bifidobacterium and Lactobacillus, without raising adverse effects compared to placebos.
However, the evidence remains inconclusive, highlighting the need for further quality studies to determine the best probiotic combinations.
7
We dove into research to explore what role probiotics might play in celiac disease (CD). While the gut microbiome impacts gluten metabolism and the immune response, the evidence on probiotics is mixed.
Some studies hint that probiotics could ease CD symptoms and tweak the immune response. However, human trials are limited and inconsistent.
Importantly, no proof exists suggesting that probiotics can prevent CD from developing. This area holds potential for future research to clarify how probiotics could fit into CD treatment.
Some studies hint that probiotics could ease CD symptoms and tweak the immune response. However, human trials are limited and inconsistent.
Importantly, no proof exists suggesting that probiotics can prevent CD from developing. This area holds potential for future research to clarify how probiotics could fit into CD treatment.
References
- Mafaldo ÍM, Araújo LM, Cabral L, Barão CE, Noronha MF, et al. Cassava (Manihot esculenta) Brazilian cultivars have different chemical compositions, present prebiotic potential, and beneficial effects on the colonic microbiota of celiac individuals. Food Res Int. 2024;195:114909. 10.1016/j.foodres.2024.114909
- Nikoloudaki O, Celano G, Polo A, Cappello C, Granehäll L, et al. Novel probiotic preparation with gluten-degrading activity and potential modulatory effects on the gut microbiota. Microbiol Spectr. 2024;12:e0352423. 10.1128/spectrum.03524-23
- Khan A, Li S, Han H, Jin WL, Ling Z, et al. A gluten degrading probiotic Bacillus subtilis LZU-GM relieve adverse effect of gluten additive food and balances gut microbiota in mice. Food Res Int. 2023;170:112960. 10.1016/j.foodres.2023.112960
- Mozafarybazargany M, Khonsari M, Sokoty L, Ejtahed HS, Qorbani M. The effects of probiotics on gastrointestinal symptoms and microbiota in patients with celiac disease: a systematic review and meta-analysis on clinical trials. Clin Exp Med. 2023;23:2773. 10.1007/s10238-022-00987-x
- Doguer C, Akalan H, Tokatlı Demirok N, Erdal B, Mete R, et al. Protective effects of Acetobacter ghanensis against gliadin toxicity in intestinal epithelial cells with immunoregulatory and gluten-digestive properties. Eur J Nutr. 2023;62:605. 10.1007/s00394-022-03015-6
- Andriulli A, Bevilacqua A, Palmieri O, Latiano A, Fontana R, et al. Healthy and pro-inflammatory gut ecology plays a crucial role in the digestion and tolerance of a novel Gluten Friendly™ bread in celiac subjects: a randomized, double blind, placebo control study. Food Funct. 2022;13:1299. 10.1039/d1fo00490e
- Jedwab CF, Roston BCMB, Toge ABFS, Echeverria IF, Tavares GOG, et al. The role of probiotics in the immune response and intestinal microbiota of children with celiac disease: a systematic review. Rev Paul Pediatr. 2021;40:e2020447. 10.1590/1984-0462/2022/40/2020447
- Wei G, Darwish G, Oppenheim FG, Schuppan D, Helmerhorst EJ. Commensal Bacterium Degrades and Detoxifies Gluten via a Highly Effective Subtilisin Enzyme. Nutrients. 2020;12. 10.3390/nu12123724
- Smecuol E, Constante M, Temprano MP, Costa AF, Moreno ML, et al. Effect of NLS super strain in symptomatic coeliac disease patients on long-term gluten-free diet - an exploratory study. Benef Microbes. 2020;11:527. 10.3920/BM2020.0016
- Marasco G, Cirota GG, Rossini B, Lungaro L, Di Biase AR, et al. Probiotics, Prebiotics and Other Dietary Supplements for Gut Microbiota Modulation in Celiac Disease Patients. Nutrients. 2020;12. 10.3390/nu12092674
- Seiler CL, Kiflen M, Stefanolo JP, Bai JC, Bercik P, et al. Probiotics for Celiac Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Am J Gastroenterol. 2020;115:1584. 10.14309/ajg.0000000000000749
- Pecora F, Persico F, Gismondi P, Fornaroli F, Iuliano S, et al. Gut Microbiota in Celiac Disease: Is There Any Role for Probiotics?. Front Immunol. 2020;11:957. 10.3389/fimmu.2020.00957
- de Almeida NEC, Esteves FG, Dos Santos-Pinto JRA, Peres de Paula C, da Cunha AF, et al. Digestion of Intact Gluten Proteins by Species: Reduction of Cytotoxicity and Proinflammatory Responses. J Agric Food Chem. 2020;68:4485. 10.1021/acs.jafc.0c01421
