5/22/2025
Last update
5/22/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 80 Researches
7.8
USERS' SCORE
Good
Based on 18 Reviews
8.6
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Blend of 10 Strains of Probiotic Bacteria: Lactobacillus acidophilus (La-14), Bifidobacterium lactis (Bl-04),Lactobacillus plantarum (Lp-115), Lactobacillus casei (Lc-11),Lactobacillus rhamnosus (Lr-32), Lactobacillus paracasei (Lpc-37),Bifidobacterium breve (Bb-03), Streptococcus thermophilus (St-21),Lactobacillus salivarius (Ls-33), Bifidobacterium longum (BI-05)
100 Billion CFU
*
Top Medical Research Studies
9.5
Bifidobacterium lactis reduced diarrhea duration
We explored the impact of Bifidobacterium animalis subsp. lactis BLa80 on diarrhea in young children through a well-structured, randomized, double-blinded, placebo-controlled study.
Our findings show that children receiving the probiotic experienced a significantly shorter duration of diarrhea and a higher recovery rate compared to those given a placebo.
Notably, we also observed beneficial changes in gut microbiome composition and gene functions that promote immune response.
This evidence suggests that Bifidobacterium lactis can effectively support recovery from acute diarrhea in children.
Our findings show that children receiving the probiotic experienced a significantly shorter duration of diarrhea and a higher recovery rate compared to those given a placebo.
Notably, we also observed beneficial changes in gut microbiome composition and gene functions that promote immune response.
This evidence suggests that Bifidobacterium lactis can effectively support recovery from acute diarrhea in children.
Read More
9
We explored the impact of Lactobacillus salivarius SNK-6 on treating and preventing diarrhea in pigeons. In our research, we compared healthy pigeons with those infected with specific strains of E. coli known to cause diarrhea. After administering L. salivarius SNK-6, we observed a notable reduction in diarrhea among treated pigeons, while control pigeons still experienced a 10% incidence of diarrhea. This suggests that boosting levels of Lactobacillus can help maintain a healthy balance in the gut, potentially preventing diarrhea in the future.
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9.5
Probiotics improve H. pylori treatments
We analyzed various studies on incorporating probiotics into treatments for Helicobacter pylori (H. pylori) infection. Our findings revealed that adding probiotics like Bifidobacterium longum improved the eradication rate significantly.
Specifically, we noted that the probiotic group experienced fewer side effects, including diarrhea, nausea, and abdominal pain. This suggests that probiotics could not only enhance the effectiveness of H. pylori treatment but also make it more comfortable for patients. Overall, these results support the use of probiotics in gastric therapies.
Specifically, we noted that the probiotic group experienced fewer side effects, including diarrhea, nausea, and abdominal pain. This suggests that probiotics could not only enhance the effectiveness of H. pylori treatment but also make it more comfortable for patients. Overall, these results support the use of probiotics in gastric therapies.
Read More
Most Useful Reviews
10
No more diarrhea
92 people found this helpful
From a small dose of 5 billion to 25 billion, I am now taking 100 billion per day. I feel excellent, with no more issues of diarrhea or constipation in my daily life. I used to constantly need to find a restroom. I highly recommend this supplement for its numerous benefits to overall health.
Read More
9
Normal bowel movement
20 people found this helpful
My personal experience began on the first day I took it. Within three hours, I felt empty and experienced gurgling sounds in my abdomen. After eating, I had gas issues but later returned to normal. There was no diarrhea or constipation, and the bloating subsided significantly. I am grateful for this change.
Read More
8.5
Normal stools again
5 people found this helpful
I tried different routines for taking it, but found that taking it on an empty stomach each morning worked best for me. I often dealt with diarrhoea and loose stools, but after using this product, my stools returned to normal. I’m happy I can now enjoy coffee without concern!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 80 Researches
7.8
- All Researches
9.5
We explored the impact of Lactobacillus acidophilus and L. plantarum on patients suffering from diarrhea-predominant irritable bowel syndrome (IBS-D). In a randomized, single-blinded clinical trial of 100 patients, some received standard IBS treatment alone while others added probiotics to their therapy.
After 12 weeks, both groups saw improvements, but those who took probiotics reported significantly better outcomes. Patients using probiotics experienced greater reductions in IBS symptoms, achieving near complete relief, while some on standard treatment still faced moderate symptoms. This suggests probiotics could enhance IBS management.
After 12 weeks, both groups saw improvements, but those who took probiotics reported significantly better outcomes. Patients using probiotics experienced greater reductions in IBS symptoms, achieving near complete relief, while some on standard treatment still faced moderate symptoms. This suggests probiotics could enhance IBS management.
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9.5
We explored the impact of Lactobacillus acidophilus and L. plantarum on patients suffering from diarrhea-predominant irritable bowel syndrome (IBS-D). In a randomized, single-blinded clinical trial of 100 patients, some received standard IBS treatment alone while others added probiotics to their therapy.
After 12 weeks, both groups saw improvements, but those who took probiotics reported significantly better outcomes. Patients using probiotics experienced greater reductions in IBS symptoms, achieving near complete relief, while some on standard treatment still faced moderate symptoms. This suggests probiotics could enhance IBS management.
After 12 weeks, both groups saw improvements, but those who took probiotics reported significantly better outcomes. Patients using probiotics experienced greater reductions in IBS symptoms, achieving near complete relief, while some on standard treatment still faced moderate symptoms. This suggests probiotics could enhance IBS management.
Read More
9.5
Lactobacillus shows promise for diarrhea
We aimed to explore how Lactobacillus acidophilus can help relieve diarrhea symptoms associated with irritable bowel syndrome (IBS) and antibiotic-associated diarrhea (AAD).
In a study with 54 patients, those taking the probiotic Neobiotic Lactobalance® for 21 days saw significant reductions in diarrhea severity and abdominal pain, with scores dropping impressively on the Gastrointestinal Symptom Rating Scale.
Fecal analysis indicated improved intestinal health, highlighting Lactobacillus's potential benefits for those struggling with these conditions.
In a study with 54 patients, those taking the probiotic Neobiotic Lactobalance® for 21 days saw significant reductions in diarrhea severity and abdominal pain, with scores dropping impressively on the Gastrointestinal Symptom Rating Scale.
Fecal analysis indicated improved intestinal health, highlighting Lactobacillus's potential benefits for those struggling with these conditions.
Read More
9.5
Probiotics improve H. pylori treatments
We analyzed various studies on incorporating probiotics into treatments for Helicobacter pylori (H. pylori) infection. Our findings revealed that adding probiotics like Bifidobacterium longum improved the eradication rate significantly.
Specifically, we noted that the probiotic group experienced fewer side effects, including diarrhea, nausea, and abdominal pain. This suggests that probiotics could not only enhance the effectiveness of H. pylori treatment but also make it more comfortable for patients. Overall, these results support the use of probiotics in gastric therapies.
Specifically, we noted that the probiotic group experienced fewer side effects, including diarrhea, nausea, and abdominal pain. This suggests that probiotics could not only enhance the effectiveness of H. pylori treatment but also make it more comfortable for patients. Overall, these results support the use of probiotics in gastric therapies.
Read More
9.5
We conducted a randomized double-blind, placebo-controlled trial with 200 participants to see how well the probiotic CECT 7347 (ES1) and its heat-treated version (HT-ES1) could help those suffering from diarrhea-predominant irritable bowel syndrome (IBS-D). After 12 weeks of treatment, both ES1 and HT-ES1 showed significant improvements in symptom severity, with marked reductions in IBS-SSS scores compared to the placebo.
Secondary benefits included better stool consistency and quality of life, making these treatments promising options for managing IBS-D symptoms. These findings reflect meaningful advancements in probiotic and postbiotic solutions.
Secondary benefits included better stool consistency and quality of life, making these treatments promising options for managing IBS-D symptoms. These findings reflect meaningful advancements in probiotic and postbiotic solutions.
Read More
User Reviews
USERS' SCORE
Good
Based on 18 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
10
No more diarrhea
92 people found this helpful
From a small dose of 5 billion to 25 billion, I am now taking 100 billion per day. I feel excellent, with no more issues of diarrhea or constipation in my daily life. I used to constantly need to find a restroom. I highly recommend this supplement for its numerous benefits to overall health.
Read More
9
Normal bowel movement
20 people found this helpful
My personal experience began on the first day I took it. Within three hours, I felt empty and experienced gurgling sounds in my abdomen. After eating, I had gas issues but later returned to normal. There was no diarrhea or constipation, and the bloating subsided significantly. I am grateful for this change.
Read More
8.5
Normal stools again
5 people found this helpful
I tried different routines for taking it, but found that taking it on an empty stomach each morning worked best for me. I often dealt with diarrhoea and loose stools, but after using this product, my stools returned to normal. I’m happy I can now enjoy coffee without concern!
Read More
9
Diarrhea resolved
4 people found this helpful
Excellent products! After years of suffering from symptoms related to candida overgrowth, I often experienced daily diarrhoea. Fortunately, within about a month of starting the 100 billion probiotics, my diarrhoea disappeared.
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7.5
Reduced frequency
4 people found this helpful
My intestinal condition has greatly improved! The frequency of my diarrhoea has significantly decreased. Combining it with dietary fibre has helped harden my stools, making bowel movements easier. I’ve also noticed a reduction in my hay fever symptoms.
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Frequently Asked Questions
9
Normal bowel movement
20 people found this helpful
My personal experience began on the first day I took it. Within three hours, I felt empty and experienced gurgling sounds in my abdomen. After eating, I had gas issues but later returned to normal. There was no diarrhea or constipation, and the bloating subsided significantly. I am grateful for this change.
9
Significant improvement
I’ve been delighted with this product. I suffer from irritable bowel syndrome and endured constant diarrhoea despite trying numerous solutions. After taking this probiotic for a week, I noticed improvement. I am very pleased and will continue using it.
9
Diarrhea resolved
4 people found this helpful
Excellent products! After years of suffering from symptoms related to candida overgrowth, I often experienced daily diarrhoea. Fortunately, within about a month of starting the 100 billion probiotics, my diarrhoea disappeared.
7.5
Reduced frequency
4 people found this helpful
My intestinal condition has greatly improved! The frequency of my diarrhoea has significantly decreased. Combining it with dietary fibre has helped harden my stools, making bowel movements easier. I’ve also noticed a reduction in my hay fever symptoms.
7.5
First effective probiotic
1 people found this helpful
As someone who had dealt with loose stools and diarrhoea from childhood, I struggled to find an effective probiotic until now. Previously, various brands failed to help until I tried this one, which gradually helped my stools become normal. However, the effects began to lessen over time, prompting me to rotate with another brand, which also provided positive results.
10
No more diarrhea
92 people found this helpful
From a small dose of 5 billion to 25 billion, I am now taking 100 billion per day. I feel excellent, with no more issues of diarrhea or constipation in my daily life. I used to constantly need to find a restroom. I highly recommend this supplement for its numerous benefits to overall health.
8.5
Normal stools again
5 people found this helpful
I tried different routines for taking it, but found that taking it on an empty stomach each morning worked best for me. I often dealt with diarrhoea and loose stools, but after using this product, my stools returned to normal. I’m happy I can now enjoy coffee without concern!
7.5
Regulated bowel movement
3 people found this helpful
It is a product I regularly purchase. Among the lactic acid bacteria available, it boasts one of the highest counts of guaranteed bacteria and performs excellently. My husband, who suffered from diarrhoea, began to have normal bowel movements after taking this product with super enzymes. Although I frequently experience diarrhoea and gas, I find this product effective. However, it must be refrigerated and is not ideal for summer purchases.
0
Worsened diarrhoea
I found Now Foods to be quite economical, yet after consuming it, my diarrhoea worsened...
10
Eliminated diarrhoea quickly
1 people found this helpful
After trying this product recommended by a friend, I found it vastly superior to the previous 30-billion strain I used. My diarrhoea, which persisted with the latter, disappeared within a week. While everyone's experience may differ, I noticed a significant improvement. I suggest trying the 100 billion product for those with bowel discomfort.
4
Strong initial effects
1 people found this helpful
This is a very powerful probiotic. Initially, I experienced diarrhoea for a couple of days after starting it, but then my bowel movements returned to normal. I would definitely recommend it for serious cases with its 100 billion bacteria count.
9
Lactobacillus acidophilus aids diarrhea recovery
We explored the impact of Lactobacillus acidophilus paired with montmorillonite powder on children suffering from rotavirus enteritis. In a study involving 94 kids, we divided them into two groups. One received standard care, while the other got the probiotic treatment as well. After five days, we found that children receiving the compound had faster relief from diarrhea, vomiting, fever, and dehydration. While there was an improvement in inflammatory responses, the difference in C-reactive protein levels wasn’t significant, and both groups reported a similar rate of side effects.
9
We conducted a multi-hospital study to tackle the common issue of antibiotic-associated diarrhea (AAD). By comparing probiotics, specifically Lactobacillus rhamnosus GG and Bifidobacterium longum BB536, with a placebo among 340 adult patients, we aimed to find out if these friendly bacteria could help.
Our findings revealed that probiotics significantly lowered both the incidence and duration of AAD compared to the placebo group. Patients reported positive outcomes, indicating high adherence to the treatment as well.
Our findings revealed that probiotics significantly lowered both the incidence and duration of AAD compared to the placebo group. Patients reported positive outcomes, indicating high adherence to the treatment as well.
8
Bifidobacterium lactis shows promise
We investigated whether Bifidobacterium lactis CCT 7858 could help reduce antibiotic-related diarrhea in hospitalized patients. In a rigorous double-blind, randomized, placebo-controlled trial with 104 participants, we found that a significant percentage—about 74.5%—of those taking the probiotic experienced no diarrhea. Additionally, fewer patients reported abdominal distension in the B. lactis group compared to the placebo. While this strain showed promise in alleviating gastrointestinal discomfort, it’s essential to note that some secondary outcomes were modest. Overall, B. lactis appears safe and may offer notable benefits alongside antibiotics.
We assessed whether a multispecies probiotic could help prevent antibiotic-associated diarrhea (AAD) in children. This randomized, quadruple-blind, placebo-controlled trial involved 350 young patients receiving broad-spectrum antibiotics.
Our findings revealed that while the probiotic did not lower the risk of AAD under the strictest criteria, it did help reduce overall diarrhea rates during antibiotic treatment and for a week afterward. This emphasizes how the definition of AAD can impact trial results and interpretations.
Our findings revealed that while the probiotic did not lower the risk of AAD under the strictest criteria, it did help reduce overall diarrhea rates during antibiotic treatment and for a week afterward. This emphasizes how the definition of AAD can impact trial results and interpretations.
References
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- Hashem B, Gaston M, Carlisle JD, Van Wick P. COMPARISON OF HAND-REARED PRONGHORN () MILK REPLACER COMPOSITIONS AND GROWTH RATES. J Zoo Wildl Med. 2024;55:1056. 10.1638/2023-0112
- Wei Q, Song LY, Rao R, Yang HW, Wen YP, et al. The Impact of Combined Therapy with Lactobacillus acidophilus and Montmorillonite Powder on the Inflammatory Response in Pediatric Rotavirus Enteritis. Int Arch Allergy Immunol. 2024. 10.1159/000542593
- Jeong JJ, Jin YJ, Ganesan R, Park HJ, Min BH, et al. Multistrain Probiotics Alleviate Diarrhea by Modulating Microbiome-Derived Metabolites and Serotonin Pathway. Probiotics Antimicrob Proteins. 2024. 10.1007/s12602-024-10232-4
- Alharbi BF, Alateek AA. Investigating the influence of probiotics in preventing Traveler's diarrhea: Meta-analysis based systematic review. Travel Med Infect Dis. 2024;59:102703. 10.1016/j.tmaid.2024.102703
- Miranda-Yuquilema J, Taboada J, Once V, Coyago M, Briñez W. Effect of Agroindustrial Waste Substrate Fermented with Lactic Acid Bacteria and Yeast on Changes in the Gut Microbiota of Guinea Pigs. Microorganisms. 2024;12. 10.3390/microorganisms12010133
- Shanshal SA, Alsaaty MH, Al-Qazaz H, Al-Zidan RN. Two Lactobacilli strains as adjuvant therapy in the management of irritable bowel syndrome: a randomized control trial. Ceska Slov Farm. 2024;72:233.
- Shanshal SA, Alsaaty MH, Al-Qazaz H, Al-Zidan RN. Two Lactobacilli strains as adjuvant therapy in the management of irritable bowel syndrome: a randomized control trial. Ceska Slov Farm. 2024;73:233.
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- Drozdov VN, Shikh EV, Astapovskii AA, Khalaidzheva KN, Solovieva SA, et al. [Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with irritable bowel syndrome with diarrhea and antibiotic-associated diarrhea]. Vopr Pitan. 2023;92:92. 10.33029/0042-8833-2023-92-4-92-103
- Lukasik J, Dierikx T, Besseling-van der Vaart I, de Meij T, Szajewska H. Multispecies Probiotic for the Prevention of Antibiotic-Associated Diarrhea in Children: A Randomized Clinical Trial. JAMA Pediatr. 2022;176:860. 10.1001/jamapediatrics.2022.1973
- Huang R, Xing HY, Liu HJ, Chen ZF, Tang BB. Efficacy of probiotics in the treatment of acute diarrhea in children: a systematic review and meta-analysis of clinical trials. Transl Pediatr. 2021;10:3248. 10.21037/tp-21-511
- Gandhar JS, De UK, Kala A, Malik YS, Yadav S, et al. Efficacy of Microencapsulated Probiotic as Adjunct Therapy on Resolution of Diarrhea, Copper-Zinc Homeostasis, Immunoglobulins, and Inflammatory Markers in Serum of Spontaneous Rotavirus-Infected Diarrhoetic Calves. Probiotics Antimicrob Proteins. 2022;14:1054. 10.1007/s12602-021-09862-9
- Kumar M, Kala A, Chaudhary LC, Agarwal N, Kochewad SA. Microencapsulated and Lyophilized Lactobacillus acidophilus Improved Gut Health and Immune Status of Preruminant Calves. Probiotics Antimicrob Proteins. 2022;14:523. 10.1007/s12602-021-09821-4
- Chorawala MR, Chauhan S, Patel R, Shah G. Cell Wall Contents of Probiotics (Lactobacillus species) Protect Against Lipopolysaccharide (LPS)-Induced Murine Colitis by Limiting Immuno-inflammation and Oxidative Stress. Probiotics Antimicrob Proteins. 2021;13:1005. 10.1007/s12602-020-09738-4
- Gunaratnam S, Diarra C, Paquette PD, Ship N, Millette M, et al. The Acid-Dependent and Independent Effects of Lactobacillus acidophilus CL1285, Lacticaseibacillus casei LBC80R, and Lacticaseibacillus rhamnosus CLR2 on Clostridioides difficile R20291. Probiotics Antimicrob Proteins. 2021;13:949. 10.1007/s12602-020-09729-5
- Shin I, Kang Y, Ahn J, Kim Y, Nam J, et al. The potential probiotic role of Lacticaseibacillus rhamnosus on growth performance, gut health, and immune responses of weaned pigs. J Anim Sci. 2025. 10.1093/jas/skaf089
- Chen K, Zeng K, Jin S, Ma Y, Cai L, et al. LRa05 in the treatment of acute diarrhea in children: a randomized controlled trial. Front Nutr. 2024;11:1479186. 10.3389/fnut.2024.1479186
- Gwee KA, Lee WRW, Chua Q, Chiou FK, Aw MM, et al. The evidence for probiotics in the treatment of digestive disorders in the pediatric population. J Gastroenterol Hepatol. 2025;40:41. 10.1111/jgh.16809
- Shah J, Adnan SH, Yousaf MS, Din SJU, Haq MU, et al. A Multi-Hospital Comparative Study on the Efficacy of Probiotics Versus Placebo in Preventing Antibiotic-Associated Diarrhea in Adult Patients. Cureus. 2024;16:e70881. 10.7759/cureus.70881
- Shawky LM, Abo El Wafa SM, Behery M, Bahr MH, Abu Alnasr MT, et al. Lactobacillus rhamnosus GG and Tannic Acid Synergistically Promote the Gut Barrier Integrity in a Rat Model of Experimental Diarrhea via Selective Immunomodulatory Cytokine Targeting. Mol Nutr Food Res. 2024;68:e2400295. 10.1002/mnfr.202400295
- Anvarifard P, Anbari M, Ghalichi F, Ghoreishi Z, Zarezadeh M. The effectiveness of probiotics as an adjunct therapy in patients under mechanical ventilation: an umbrella systematic review and meta-analysis. Food Funct. 2024;15:5737. 10.1039/d3fo04653b
- Abdulah DM, Sulaiman SJ, Ahmed ZW. Effect of probiotics plus zinc supplementation on clinical outcomes of infants and children with acute infectious diarrhea: a randomized controlled trial. Clin Exp Pediatr. 2024;67:203. 10.3345/cep.2023.01340
- Waitzberg D, Guarner F, Hojsak I, Ianiro G, Polk DB, et al. Can the Evidence-Based Use of Probiotics (Notably Saccharomyces boulardii CNCM I-745 and Lactobacillus rhamnosus GG) Mitigate the Clinical Effects of Antibiotic-Associated Dysbiosis?. Adv Ther. 2024;41:901. 10.1007/s12325-024-02783-3
- Saviano A, Petruzziello C, Cancro C, Macerola N, Petti A, et al. The Efficacy of a Mix of Probiotics ( LMG P-27481 and GG ATCC 53103) in Preventing Antibiotic-Associated Diarrhea and Infection in Hospitalized Patients: Single-Center, Open-Label, Randomized Trial. Microorganisms. 2024;12. 10.3390/microorganisms12010198
- Poeta M, Cioffi V, Tarallo A, Damiano C, Lo Vecchio A, et al. Postbiotic Preparation of against Diarrhea and Oxidative Stress Induced by Spike Protein of SARS-CoV-2 in Human Enterocytes. Antioxidants (Basel). 2023;12. 10.3390/antiox12101878
- Mego M, Danis R, Chovanec J, Jurisova S, Bystricky B, et al. Randomized double-blind, placebo-controlled multicenter phase III study of prevention of irinotecan-induced diarrhea by a probiotic mixture containing Bifidobacterium BB-12 LGG in colorectal cancer patients. Front Oncol. 2023;13:1168654. 10.3389/fonc.2023.1168654
- Yang Q, Hu Z, Lei Y, Li X, Xu C, et al. Overview of systematic reviews of probiotics in the prevention and treatment of antibiotic-associated diarrhea in children. Front Pharmacol. 2023;14:1153070. 10.3389/fphar.2023.1153070
- Niu H, Zhou X, Liu P, Wu Y, Lyu L, et al. Lactobacillus rhamnosus MN-431 Metabolic Tryptophan Alleviates Complementary Food-Induced Diarrhea through PXR-NF-κB Pathway and AHR-Th17 Cell Response Pathways. Mol Nutr Food Res. 2023;67:e2200530. 10.1002/mnfr.202200530
- Li J, Li Q, Wu Q, Gao N, Wang Z, et al. Exopolysaccharides of Lactobacillus rhamnosus GG ameliorate Salmonella typhimurium-induced intestinal inflammation via the TLR4/NF-κB/MAPK pathway. J Anim Sci Biotechnol. 2023;14:23. 10.1186/s40104-023-00830-7
- He Q, Lu S, Wang J, Xu C, Qu W, et al. and Berberine Alleviated Yak Calves' Diarrhea via Accommodating Oxidation Resistance, Inflammatory Factors, and Intestinal Microbiota. Animals (Basel). 2024;14. 10.3390/ani14162419
- Fan W, Zhu Y, Hou H, Yao J, Zhu L, et al. Treatment and prevention of pigeon diarrhea through the application of Lactobacillus SNK-6. Poult Sci. 2024;103:103476. 10.1016/j.psj.2024.103476
- Cuevas-Gómez I, de Andrés J, Cardenas N, Espinosa-Martos I, Jiménez E. Feed supplementation with Ligilactobacillus salivarius PS21603 optimises intestinal morphology and gut microbiota composition in weaned piglets. Benef Microbes. 2024;15:195. 10.1163/18762891-bja00001
- Molina RA, Villar MD, Miranda MH, Maldonado NC, Vignolo GM, et al. A multi-strain probiotic promoted recovery of puppies from gastroenteritis in a randomized, double-blind, placebo-controlled study. Can Vet J. 2023;64:666.
- Cuevas-Gómez I, de Andrés J, Cardenas N, Espinosa-Martos I, Jiménez E. Safety assessment and characterisation of PS21603 as potential feed additive for swine. Benef Microbes. 2022;13:397. 10.3920/BM2022.0020
- Sun Z, Li H, Li Y, Qiao J. , a Potential Probiotic to Improve the Health of LPS-Challenged Piglet Intestine by Alleviating Inflammation as Well as Oxidative Stress in a Dose-Dependent Manner During Weaning Transition. Front Vet Sci. 2020;7:547425. 10.3389/fvets.2020.547425
- Azagra-Boronat I, Massot-Cladera M, Knipping K, Garssen J, Ben Amor K, et al. Strain-Specific Probiotic Properties of Bifidobacteria and Lactobacilli for the Prevention of Diarrhea Caused by Rotavirus in a Preclinical Model. Nutrients. 2020;12. 10.3390/nu12020498
- Sayan H, Assavacheep P, Angkanaporn K, Assavacheep A. Effect of Lactobacillus salivarius on growth performance, diarrhea incidence, fecal bacterial population and intestinal morphology of suckling pigs challenged with F4+ enterotoxigenic Escherichia coli. Asian-Australas J Anim Sci. 2018;31:1308. 10.5713/ajas.17.0746
- Skórka A, Pieścik-Lech M, Kołodziej M, Szajewska H. To add or not to add probiotics to infant formulae? An updated systematic review. Benef Microbes. 2017;8:717. 10.3920/BM2016.0233
- Maldonado NC, Chiaraviglio J, Bru E, De Chazal L, Santos V, et al. Effect of Milk Fermented with Lactic Acid Bacteria on Diarrheal Incidence, Growth Performance and Microbiological and Blood Profiles of Newborn Dairy Calves. Probiotics Antimicrob Proteins. 2018;10:668. 10.1007/s12602-017-9308-4
- Lomasney KW, Cryan JF, Hyland NP. Converging effects of a Bifidobacterium and Lactobacillus probiotic strain on mouse intestinal physiology. Am J Physiol Gastrointest Liver Physiol. 2014;307:G241. 10.1152/ajpgi.00401.2013
- Tsai CC, Lin PP, Hsieh YM. Three Lactobacillus strains from healthy infant stool inhibit enterotoxigenic Escherichia coli grown in vitro. Anaerobe. 2008;14:61. 10.1016/j.anaerobe.2007.11.003
- Casey PG, Gardiner GE, Casey G, Bradshaw B, Lawlor PG, et al. A five-strain probiotic combination reduces pathogen shedding and alleviates disease signs in pigs challenged with Salmonella enterica Serovar Typhimurium. Appl Environ Microbiol. 2007;73:1858.
- Sartor RB. Probiotic therapy of intestinal inflammation and infections. Curr Opin Gastroenterol. 2005;21:44.
- Tanashat M, Abuelazm M, Abouzid M, Al-Ajlouni YA, Ramadan A, et al. Efficacy of probiotics regimens for Helicobacter pylori eradication: A systematic review, pairwise, and network meta-analysis of randomized controlled trials. Clin Nutr ESPEN. 2025;65:424. 10.1016/j.clnesp.2024.11.016
- Moreno-Muñoz JA, Ojeda JD, López JJ. A Probiotic Bacterium with Activity against the Most Frequent Bacteria and Viruses Causing Pediatric Diarrhea: subsp. CECT 7210 ( IM1). Microorganisms. 2024;12. 10.3390/microorganisms12061183
- Srivastava S, Basak U, Naghibi M, Vijayakumar V, Parihar R, et al. A randomized double-blind, placebo-controlled trial to evaluate the safety and efficacy of live CECT 7347 (ES1) and heat-treated CECT 7347 (HT-ES1) in participants with diarrhea-predominant irritable bowel syndrome. Gut Microbes. 2024;16:2338322. 10.1080/19490976.2024.2338322
- Lenoir M, Wienke J, Fardao-Beyler F, Roese N. An 8-Week Course of Bifidobacterium longum 35624 Is Associated with a Reduction in the Symptoms of Irritable Bowel Syndrome. Probiotics Antimicrob Proteins. 2025;17:315. 10.1007/s12602-023-10151-w
- Chen K, Jin S, Ma Y, Cai L, Xu P, et al. Adjunctive efficacy of Lactis XLTG11 for Acute diarrhea in children: A randomized, blinded, placebo-controlled study. Nutrition. 2023;111:112052. 10.1016/j.nut.2023.112052
- Li W, Zhang S, Wang Y, Bian H, Yu S, et al. Complex probiotics alleviate ampicillin-induced antibiotic-associated diarrhea in mice. Front Microbiol. 2023;14:1156058. 10.3389/fmicb.2023.1156058
- Mizutani Y, Kawamoto S, Takahashi M, Doi H, Wakida K, et al. Efficacy and Safety of Synbiotics in Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation: A Randomized, Double-blinded, Placebo-controlled Pilot Study. Intern Med. 2023;62:2949. 10.2169/internalmedicine.1314-22
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