5/24/2025
Last update
5/24/2025
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 1 Review
8.4
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin E (as d-alpha Tocopheryl Acetate)
268 mg
1787%
Top Medical Research Studies
7
Vitamin E benefits menopause mood disorders
We explored the effects of vitamin E on anxiety and depression, particularly in the context of menopause-related mood disorders. To conduct this research, we studied ovariectomized mice—an animal model representing estrogen deficiency.
Our findings indicated that ovariectomized mice exhibited behaviors linked to depression and anxiety. Notably, these mice had higher levels of corticosterone, a hormone that signals stress, compared to a control group. We observed that administering α-tocopherol (a form of vitamin E) and tocotrienol-rich palm oil extract significantly reduced these mood disturbances over a two-week period.
While both treatments helped alleviate anxiety and depressive behaviors, tocotrienol-rich palm oil extract showed a more pronounced effect, particularly in mice under chronic stress. Additionally, both forms of vitamin E were effective in lowering elevated corticosterone levels, suggesting that they may help modulate the body’s stress response.
Overall, our research supports the potential of vitamin E as a promising treatment for mood disorders associated with menopause, highlighting its role in improving psychological well-being.
Our findings indicated that ovariectomized mice exhibited behaviors linked to depression and anxiety. Notably, these mice had higher levels of corticosterone, a hormone that signals stress, compared to a control group. We observed that administering α-tocopherol (a form of vitamin E) and tocotrienol-rich palm oil extract significantly reduced these mood disturbances over a two-week period.
While both treatments helped alleviate anxiety and depressive behaviors, tocotrienol-rich palm oil extract showed a more pronounced effect, particularly in mice under chronic stress. Additionally, both forms of vitamin E were effective in lowering elevated corticosterone levels, suggesting that they may help modulate the body’s stress response.
Overall, our research supports the potential of vitamin E as a promising treatment for mood disorders associated with menopause, highlighting its role in improving psychological well-being.
Read More
8
Vitamin E alleviates anxiety symptoms
In our exploration of how vitamin E affects anxiety, we studied male mice that were exposed to heat stress, which is known to trigger symptoms of anxiety and depression. We divided the mice into five groups: a control group, a heat stress group, and three treatment groups that received either vitamin E, coenzyme Q10, or a combination of both.
Over the course of 14 days, the heat-stressed mice underwent daily treatments, and we conducted various behavioral tests to measure signs of anxiety and depression. Remarkably, we discovered that both vitamin E alone and in combination with coenzyme Q10 provided significant relief from anxiety-related behaviors.
This was evident as we observed lowered anxiety levels and decreased despair behaviors in the treated groups compared to those that only experienced heat stress. Additionally, we noted a reduction in serum levels of corticosterone, a hormone associated with stress, which further supports the beneficial effects of vitamin E.
By modulating inflammatory pathways and influencing brain function, vitamin E, along with coenzyme Q10, appears to help counteract the negative emotional impacts of environmental stressors like heat.
Over the course of 14 days, the heat-stressed mice underwent daily treatments, and we conducted various behavioral tests to measure signs of anxiety and depression. Remarkably, we discovered that both vitamin E alone and in combination with coenzyme Q10 provided significant relief from anxiety-related behaviors.
This was evident as we observed lowered anxiety levels and decreased despair behaviors in the treated groups compared to those that only experienced heat stress. Additionally, we noted a reduction in serum levels of corticosterone, a hormone associated with stress, which further supports the beneficial effects of vitamin E.
By modulating inflammatory pathways and influencing brain function, vitamin E, along with coenzyme Q10, appears to help counteract the negative emotional impacts of environmental stressors like heat.
Read More
Most Useful Reviews
7.5
Reduced anxiety
3 people found this helpful
I can feel the effect; this is a repeat purchase for me. Since I began taking this supplement daily, I’ve felt less fatigued. Additionally, it has had an unexpected beauty impact. The adult acne that appeared when my overall skin condition deteriorated has vanished before I realised it. Even through the pandemic, I've managed to consume high-quality natural vitamin E, which has contributed to reducing my anxiety.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
- All Researches
8
Vitamin E alleviates anxiety symptoms
In our exploration of how vitamin E affects anxiety, we studied male mice that were exposed to heat stress, which is known to trigger symptoms of anxiety and depression. We divided the mice into five groups: a control group, a heat stress group, and three treatment groups that received either vitamin E, coenzyme Q10, or a combination of both.
Over the course of 14 days, the heat-stressed mice underwent daily treatments, and we conducted various behavioral tests to measure signs of anxiety and depression. Remarkably, we discovered that both vitamin E alone and in combination with coenzyme Q10 provided significant relief from anxiety-related behaviors.
This was evident as we observed lowered anxiety levels and decreased despair behaviors in the treated groups compared to those that only experienced heat stress. Additionally, we noted a reduction in serum levels of corticosterone, a hormone associated with stress, which further supports the beneficial effects of vitamin E.
By modulating inflammatory pathways and influencing brain function, vitamin E, along with coenzyme Q10, appears to help counteract the negative emotional impacts of environmental stressors like heat.
Over the course of 14 days, the heat-stressed mice underwent daily treatments, and we conducted various behavioral tests to measure signs of anxiety and depression. Remarkably, we discovered that both vitamin E alone and in combination with coenzyme Q10 provided significant relief from anxiety-related behaviors.
This was evident as we observed lowered anxiety levels and decreased despair behaviors in the treated groups compared to those that only experienced heat stress. Additionally, we noted a reduction in serum levels of corticosterone, a hormone associated with stress, which further supports the beneficial effects of vitamin E.
By modulating inflammatory pathways and influencing brain function, vitamin E, along with coenzyme Q10, appears to help counteract the negative emotional impacts of environmental stressors like heat.
Read More
7
Vitamin E benefits menopause mood disorders
We explored the effects of vitamin E on anxiety and depression, particularly in the context of menopause-related mood disorders. To conduct this research, we studied ovariectomized mice—an animal model representing estrogen deficiency.
Our findings indicated that ovariectomized mice exhibited behaviors linked to depression and anxiety. Notably, these mice had higher levels of corticosterone, a hormone that signals stress, compared to a control group. We observed that administering α-tocopherol (a form of vitamin E) and tocotrienol-rich palm oil extract significantly reduced these mood disturbances over a two-week period.
While both treatments helped alleviate anxiety and depressive behaviors, tocotrienol-rich palm oil extract showed a more pronounced effect, particularly in mice under chronic stress. Additionally, both forms of vitamin E were effective in lowering elevated corticosterone levels, suggesting that they may help modulate the body’s stress response.
Overall, our research supports the potential of vitamin E as a promising treatment for mood disorders associated with menopause, highlighting its role in improving psychological well-being.
Our findings indicated that ovariectomized mice exhibited behaviors linked to depression and anxiety. Notably, these mice had higher levels of corticosterone, a hormone that signals stress, compared to a control group. We observed that administering α-tocopherol (a form of vitamin E) and tocotrienol-rich palm oil extract significantly reduced these mood disturbances over a two-week period.
While both treatments helped alleviate anxiety and depressive behaviors, tocotrienol-rich palm oil extract showed a more pronounced effect, particularly in mice under chronic stress. Additionally, both forms of vitamin E were effective in lowering elevated corticosterone levels, suggesting that they may help modulate the body’s stress response.
Overall, our research supports the potential of vitamin E as a promising treatment for mood disorders associated with menopause, highlighting its role in improving psychological well-being.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Reduced anxiety
3 people found this helpful
I can feel the effect; this is a repeat purchase for me. Since I began taking this supplement daily, I’ve felt less fatigued. Additionally, it has had an unexpected beauty impact. The adult acne that appeared when my overall skin condition deteriorated has vanished before I realised it. Even through the pandemic, I've managed to consume high-quality natural vitamin E, which has contributed to reducing my anxiety.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Mahmoudi J, Kazmi S, Vatandoust S, Athari SZ, Sadigh-Eteghad S, et al. Coenzyme Q10 and vitamin E alleviate heat stress-induced mood disturbances in male mice: Modulation of inflammatory pathways and the HPA axis. Behav Brain Res. 2025;476:115259. 10.1016/j.bbr.2024.115259
- Liang G, Kow ASF, Lee YZ, Yusof R, Tham CL, et al. Ameliorative effect of α-tocopherol and tocotrienol-rich palm oil extract on menopause-associated mood disorder in ovariectomized mice. Biochem Biophys Res Commun. 2024;734:150443. 10.1016/j.bbrc.2024.150443
