5/24/2025
Last update
5/24/2025
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.8
USERS' SCORE
Good
Based on 4 Reviews
8.3
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin E (as d-alpha Tocopheryl Acetate)
268 mg
1787%
Top Medical Research Studies
8
We examined the effects of gamma-tocopherol, a major form of vitamin E, on cancer treatment and prevention. This powerful antioxidant is noted for its ability to combat oxidative stress, which plays a significant role in the development and progression of various cancers.
In several studies, we observed that gamma-tocopherol not only neutralizes harmful reactive oxygen species but also exhibits anti-inflammatory properties. These characteristics help reduce chronic inflammation tied to cancer risks. Furthermore, it has shown the potential to inhibit tumor growth, induce cancer cell death, and restrict blood vessel formation that tumors require to grow.
Specifically, findings indicated that gamma-tocopherol is particularly effective in cancers such as prostate, lung, and colon. With promising results from both preclinical and clinical trials, there is a growing interest in how this natural compound can be beneficial in cancer management.
While we noted excellent tolerance at normal doses, it’s essential to consider careful monitoring at higher levels to avoid any adverse effects. Hence, we believe that ongoing research and advancements in drug delivery methods could further enhance its effectiveness.
In several studies, we observed that gamma-tocopherol not only neutralizes harmful reactive oxygen species but also exhibits anti-inflammatory properties. These characteristics help reduce chronic inflammation tied to cancer risks. Furthermore, it has shown the potential to inhibit tumor growth, induce cancer cell death, and restrict blood vessel formation that tumors require to grow.
Specifically, findings indicated that gamma-tocopherol is particularly effective in cancers such as prostate, lung, and colon. With promising results from both preclinical and clinical trials, there is a growing interest in how this natural compound can be beneficial in cancer management.
While we noted excellent tolerance at normal doses, it’s essential to consider careful monitoring at higher levels to avoid any adverse effects. Hence, we believe that ongoing research and advancements in drug delivery methods could further enhance its effectiveness.
Read More
9
Vitamin E reprograms immune cells
Our study delves into the innovative use of vitamin E as part of a lipid nanosystem to change the behavior of tumor-associated macrophages (TAMs). These immune cells typically foster a pro-cancer environment, and we aimed to see if reprogramming them could impact pancreatic cancer's progression and metastasis, particularly in the liver.
We found that treating M2-polarized macrophages with a nanoemulsion of vitamin E and sphingomyelin made them shift from a pro-tumor state to a more neutral or anti-tumor state. The treatment decreased markers associated with the M2 phenotype, which promotes cancer growth, and increased markers of the M1 phenotype that fight cancer. Notably, when we coupled this treatment with a drug that inhibits TGF-βR1, it led to reduced tumor growth and liver metastasis in models of pancreatic cancer.
This work underscores vitamin E's potential as a part of a broader therapeutic strategy aimed at reprogramming immune cells to better combat cancer. By targeting TAMs, we are opening new avenues for treatments that not only manage the primary tumors but also curb the spread of cancer to other organs, like the liver, which is vital for improving outcomes for patients dealing with aggressive forms of the disease.
We found that treating M2-polarized macrophages with a nanoemulsion of vitamin E and sphingomyelin made them shift from a pro-tumor state to a more neutral or anti-tumor state. The treatment decreased markers associated with the M2 phenotype, which promotes cancer growth, and increased markers of the M1 phenotype that fight cancer. Notably, when we coupled this treatment with a drug that inhibits TGF-βR1, it led to reduced tumor growth and liver metastasis in models of pancreatic cancer.
This work underscores vitamin E's potential as a part of a broader therapeutic strategy aimed at reprogramming immune cells to better combat cancer. By targeting TAMs, we are opening new avenues for treatments that not only manage the primary tumors but also curb the spread of cancer to other organs, like the liver, which is vital for improving outcomes for patients dealing with aggressive forms of the disease.
Read More
9
We observed that vitamin E succinate (VES) has the potential to serve as a tool for fighting cancer, particularly by targeting a protein called fat mass and obesity-associated protein (FTO), which plays a role in tumor growth. This study highlights how VES can act as a degrader of FTO, leading to its suppression, thereby hindering tumor progression and enhancing the effectiveness of immunotherapy.
When VES binds to both FTO and an associated protein called DTX2, it boosts the interaction between them. This ultimately promotes the process that marks FTO for degradation. In animal models, treatment with VES resulted in reduced tumor size and a significant improvement in the immune response against tumors, suggesting a promising avenue for enhancing cancer treatment strategies.
Furthermore, reducing FTO levels increased the methylation of a specific gene, LIF, involved in regulating immune responses, which allowed melanoma cells to become more susceptible to T cell attacks. Overall, these findings shed light on how VES not only degrades FTO but also holds the potential to improve outcomes for patients undergoing cancer therapies.
When VES binds to both FTO and an associated protein called DTX2, it boosts the interaction between them. This ultimately promotes the process that marks FTO for degradation. In animal models, treatment with VES resulted in reduced tumor size and a significant improvement in the immune response against tumors, suggesting a promising avenue for enhancing cancer treatment strategies.
Furthermore, reducing FTO levels increased the methylation of a specific gene, LIF, involved in regulating immune responses, which allowed melanoma cells to become more susceptible to T cell attacks. Overall, these findings shed light on how VES not only degrades FTO but also holds the potential to improve outcomes for patients undergoing cancer therapies.
Read More
Most Useful Reviews
9
Supports cancer prevention
1 people found this helpful
Vitamin E is a fat-soluble vitamin known for its antioxidant and radioprotective properties. It aids in the synthesis of heme and proteins, cell proliferation, and cellular metabolism. It enhances tissue oxygen consumption, supports heart function, and contributes to red blood cell formation. Vitamin E boosts the immune system, combats oxidative stress, and plays a preventive role against cancer. Overall, it is of good quality, well-packaged, and contributes to a calm nervous system as well as fast metabolism.
Read More
7.5
Effective pain relief
1 people found this helpful
It has previously been prescribed for breast disease. I believe it was effective as I took it alongside vitamin A, which alleviated the pain from mastopathy. This time, I wish to continue using it to prevent cancer.
Read More
7.5
Promotes general health
1 people found this helpful
I consistently take vitamin E due to its numerous benefits, especially for women over 40. It aids in detoxifying the body from harmful substances, enhances resistance to viruses, slows ageing, rejuvenates cells, benefits the nervous system, stabilises blood pressure, and reduces the risk of cancer, blood clots, pigmentation, and cardiovascular diseases.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.8
- All Researches
9
This study focuses on the innovative use of self-assembled nanoparticles to improve cancer treatment, particularly for triple-negative breast cancer. By leveraging computer-aided strategies, researchers identified key properties that guide the creation of these nanoparticles.
We observed that vitamin E, when combined with hydroxychloroquine and bortezomib, resulted in a unique nanoparticle formulation. This formulation not only helps reduce harmful M2-type tumor-associated macrophages but also induces a process known as immunogenic cell death in tumor cells.
In experiments conducted on mouse models, the nanoparticles displayed promising results. They effectively decreased levels of regulatory T cells and transforming growth factor-β while enhancing the presence of cytotoxic T lymphocytes. Moreover, they inhibited the secretion of a pro-inflammatory factor known as Interleukin-6, which can contribute to tumor growth and poor immune response.
The combination of vitamin E and other compounds showcases a dual modulation approach, potentially reprogramming the tumor microenvironment to enhance chemotherapy combined with immunotherapy.
However, while the study highlights potential benefits, it also suggests that isolating vitamin E's effect in cancer treatment is challenging due to its application alongside other treatments.
We observed that vitamin E, when combined with hydroxychloroquine and bortezomib, resulted in a unique nanoparticle formulation. This formulation not only helps reduce harmful M2-type tumor-associated macrophages but also induces a process known as immunogenic cell death in tumor cells.
In experiments conducted on mouse models, the nanoparticles displayed promising results. They effectively decreased levels of regulatory T cells and transforming growth factor-β while enhancing the presence of cytotoxic T lymphocytes. Moreover, they inhibited the secretion of a pro-inflammatory factor known as Interleukin-6, which can contribute to tumor growth and poor immune response.
The combination of vitamin E and other compounds showcases a dual modulation approach, potentially reprogramming the tumor microenvironment to enhance chemotherapy combined with immunotherapy.
However, while the study highlights potential benefits, it also suggests that isolating vitamin E's effect in cancer treatment is challenging due to its application alongside other treatments.
Read More
9
Vitamin E reprograms immune cells
Our study delves into the innovative use of vitamin E as part of a lipid nanosystem to change the behavior of tumor-associated macrophages (TAMs). These immune cells typically foster a pro-cancer environment, and we aimed to see if reprogramming them could impact pancreatic cancer's progression and metastasis, particularly in the liver.
We found that treating M2-polarized macrophages with a nanoemulsion of vitamin E and sphingomyelin made them shift from a pro-tumor state to a more neutral or anti-tumor state. The treatment decreased markers associated with the M2 phenotype, which promotes cancer growth, and increased markers of the M1 phenotype that fight cancer. Notably, when we coupled this treatment with a drug that inhibits TGF-βR1, it led to reduced tumor growth and liver metastasis in models of pancreatic cancer.
This work underscores vitamin E's potential as a part of a broader therapeutic strategy aimed at reprogramming immune cells to better combat cancer. By targeting TAMs, we are opening new avenues for treatments that not only manage the primary tumors but also curb the spread of cancer to other organs, like the liver, which is vital for improving outcomes for patients dealing with aggressive forms of the disease.
We found that treating M2-polarized macrophages with a nanoemulsion of vitamin E and sphingomyelin made them shift from a pro-tumor state to a more neutral or anti-tumor state. The treatment decreased markers associated with the M2 phenotype, which promotes cancer growth, and increased markers of the M1 phenotype that fight cancer. Notably, when we coupled this treatment with a drug that inhibits TGF-βR1, it led to reduced tumor growth and liver metastasis in models of pancreatic cancer.
This work underscores vitamin E's potential as a part of a broader therapeutic strategy aimed at reprogramming immune cells to better combat cancer. By targeting TAMs, we are opening new avenues for treatments that not only manage the primary tumors but also curb the spread of cancer to other organs, like the liver, which is vital for improving outcomes for patients dealing with aggressive forms of the disease.
Read More
9
We observed that vitamin E succinate (VES) has the potential to serve as a tool for fighting cancer, particularly by targeting a protein called fat mass and obesity-associated protein (FTO), which plays a role in tumor growth. This study highlights how VES can act as a degrader of FTO, leading to its suppression, thereby hindering tumor progression and enhancing the effectiveness of immunotherapy.
When VES binds to both FTO and an associated protein called DTX2, it boosts the interaction between them. This ultimately promotes the process that marks FTO for degradation. In animal models, treatment with VES resulted in reduced tumor size and a significant improvement in the immune response against tumors, suggesting a promising avenue for enhancing cancer treatment strategies.
Furthermore, reducing FTO levels increased the methylation of a specific gene, LIF, involved in regulating immune responses, which allowed melanoma cells to become more susceptible to T cell attacks. Overall, these findings shed light on how VES not only degrades FTO but also holds the potential to improve outcomes for patients undergoing cancer therapies.
When VES binds to both FTO and an associated protein called DTX2, it boosts the interaction between them. This ultimately promotes the process that marks FTO for degradation. In animal models, treatment with VES resulted in reduced tumor size and a significant improvement in the immune response against tumors, suggesting a promising avenue for enhancing cancer treatment strategies.
Furthermore, reducing FTO levels increased the methylation of a specific gene, LIF, involved in regulating immune responses, which allowed melanoma cells to become more susceptible to T cell attacks. Overall, these findings shed light on how VES not only degrades FTO but also holds the potential to improve outcomes for patients undergoing cancer therapies.
Read More
9
Vitamin E enhances cancer treatment
In our exploration of breast cancer treatments, we investigated how nanoparticles infused with vitamin E could effectively deliver cancer medications. Our study specifically focused on drug-resistant HER2-positive breast cancer, which is challenging to treat due to its tendency to develop resistance to standard therapies.
We developed nanoparticles from human serum albumin linked with vitamin E, designed to encapsulate and deliver targeted cancer drugs. Through sophisticated methods, including infrared spectroscopy and cell viability assays, we confirmed that the nanoparticles efficiently bound the drugs and released them over time.
Our results revealed that combining these vitamin E-laden nanoparticles—specifically Lapatinib and Letrozole—in a carefully designed ratio led to a substantial reduction in tumor growth. This combination not only outperformed individual treatments but also proved effective in drug-resistant cell lines, showcasing the potential of vitamin E as a vehicle for enhancing cancer therapy.
Overall, while the study highlighted the promising role of vitamin E in this innovative drug delivery approach, it primarily emphasized the combined effects of the therapies rather than isolating vitamin E's impact alone.
We developed nanoparticles from human serum albumin linked with vitamin E, designed to encapsulate and deliver targeted cancer drugs. Through sophisticated methods, including infrared spectroscopy and cell viability assays, we confirmed that the nanoparticles efficiently bound the drugs and released them over time.
Our results revealed that combining these vitamin E-laden nanoparticles—specifically Lapatinib and Letrozole—in a carefully designed ratio led to a substantial reduction in tumor growth. This combination not only outperformed individual treatments but also proved effective in drug-resistant cell lines, showcasing the potential of vitamin E as a vehicle for enhancing cancer therapy.
Overall, while the study highlighted the promising role of vitamin E in this innovative drug delivery approach, it primarily emphasized the combined effects of the therapies rather than isolating vitamin E's impact alone.
Read More
8
We examined the effects of gamma-tocopherol, a major form of vitamin E, on cancer treatment and prevention. This powerful antioxidant is noted for its ability to combat oxidative stress, which plays a significant role in the development and progression of various cancers.
In several studies, we observed that gamma-tocopherol not only neutralizes harmful reactive oxygen species but also exhibits anti-inflammatory properties. These characteristics help reduce chronic inflammation tied to cancer risks. Furthermore, it has shown the potential to inhibit tumor growth, induce cancer cell death, and restrict blood vessel formation that tumors require to grow.
Specifically, findings indicated that gamma-tocopherol is particularly effective in cancers such as prostate, lung, and colon. With promising results from both preclinical and clinical trials, there is a growing interest in how this natural compound can be beneficial in cancer management.
While we noted excellent tolerance at normal doses, it’s essential to consider careful monitoring at higher levels to avoid any adverse effects. Hence, we believe that ongoing research and advancements in drug delivery methods could further enhance its effectiveness.
In several studies, we observed that gamma-tocopherol not only neutralizes harmful reactive oxygen species but also exhibits anti-inflammatory properties. These characteristics help reduce chronic inflammation tied to cancer risks. Furthermore, it has shown the potential to inhibit tumor growth, induce cancer cell death, and restrict blood vessel formation that tumors require to grow.
Specifically, findings indicated that gamma-tocopherol is particularly effective in cancers such as prostate, lung, and colon. With promising results from both preclinical and clinical trials, there is a growing interest in how this natural compound can be beneficial in cancer management.
While we noted excellent tolerance at normal doses, it’s essential to consider careful monitoring at higher levels to avoid any adverse effects. Hence, we believe that ongoing research and advancements in drug delivery methods could further enhance its effectiveness.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Supports cancer prevention
1 people found this helpful
Vitamin E is a fat-soluble vitamin known for its antioxidant and radioprotective properties. It aids in the synthesis of heme and proteins, cell proliferation, and cellular metabolism. It enhances tissue oxygen consumption, supports heart function, and contributes to red blood cell formation. Vitamin E boosts the immune system, combats oxidative stress, and plays a preventive role against cancer. Overall, it is of good quality, well-packaged, and contributes to a calm nervous system as well as fast metabolism.
Read More
7.5
Effective pain relief
1 people found this helpful
It has previously been prescribed for breast disease. I believe it was effective as I took it alongside vitamin A, which alleviated the pain from mastopathy. This time, I wish to continue using it to prevent cancer.
Read More
7.5
Promotes general health
1 people found this helpful
I consistently take vitamin E due to its numerous benefits, especially for women over 40. It aids in detoxifying the body from harmful substances, enhances resistance to viruses, slows ageing, rejuvenates cells, benefits the nervous system, stabilises blood pressure, and reduces the risk of cancer, blood clots, pigmentation, and cardiovascular diseases.
Read More
7.5
Cancer-fighting antioxidant
1 people found this helpful
E-400 Vitamin E is a powerful antioxidant with tocopheryl acetate and provides benefits not only in fighting cancer but also for skin and hair health. The capsules are round, red, and odourless, and a consistent dosage of one capsule per day suffices to enjoy its advantages.
Read More
Frequently Asked Questions
7.5
Effective pain relief
1 people found this helpful
It has previously been prescribed for breast disease. I believe it was effective as I took it alongside vitamin A, which alleviated the pain from mastopathy. This time, I wish to continue using it to prevent cancer.
9
Supports cancer prevention
1 people found this helpful
Vitamin E is a fat-soluble vitamin known for its antioxidant and radioprotective properties. It aids in the synthesis of heme and proteins, cell proliferation, and cellular metabolism. It enhances tissue oxygen consumption, supports heart function, and contributes to red blood cell formation. Vitamin E boosts the immune system, combats oxidative stress, and plays a preventive role against cancer. Overall, it is of good quality, well-packaged, and contributes to a calm nervous system as well as fast metabolism.
7.5
Promotes general health
1 people found this helpful
I consistently take vitamin E due to its numerous benefits, especially for women over 40. It aids in detoxifying the body from harmful substances, enhances resistance to viruses, slows ageing, rejuvenates cells, benefits the nervous system, stabilises blood pressure, and reduces the risk of cancer, blood clots, pigmentation, and cardiovascular diseases.
7.5
Cancer-fighting antioxidant
1 people found this helpful
E-400 Vitamin E is a powerful antioxidant with tocopheryl acetate and provides benefits not only in fighting cancer but also for skin and hair health. The capsules are round, red, and odourless, and a consistent dosage of one capsule per day suffices to enjoy its advantages.
8
We examined the effects of gamma-tocopherol, a major form of vitamin E, on cancer treatment and prevention. This powerful antioxidant is noted for its ability to combat oxidative stress, which plays a significant role in the development and progression of various cancers.
In several studies, we observed that gamma-tocopherol not only neutralizes harmful reactive oxygen species but also exhibits anti-inflammatory properties. These characteristics help reduce chronic inflammation tied to cancer risks. Furthermore, it has shown the potential to inhibit tumor growth, induce cancer cell death, and restrict blood vessel formation that tumors require to grow.
Specifically, findings indicated that gamma-tocopherol is particularly effective in cancers such as prostate, lung, and colon. With promising results from both preclinical and clinical trials, there is a growing interest in how this natural compound can be beneficial in cancer management.
While we noted excellent tolerance at normal doses, it’s essential to consider careful monitoring at higher levels to avoid any adverse effects. Hence, we believe that ongoing research and advancements in drug delivery methods could further enhance its effectiveness.
In several studies, we observed that gamma-tocopherol not only neutralizes harmful reactive oxygen species but also exhibits anti-inflammatory properties. These characteristics help reduce chronic inflammation tied to cancer risks. Furthermore, it has shown the potential to inhibit tumor growth, induce cancer cell death, and restrict blood vessel formation that tumors require to grow.
Specifically, findings indicated that gamma-tocopherol is particularly effective in cancers such as prostate, lung, and colon. With promising results from both preclinical and clinical trials, there is a growing interest in how this natural compound can be beneficial in cancer management.
While we noted excellent tolerance at normal doses, it’s essential to consider careful monitoring at higher levels to avoid any adverse effects. Hence, we believe that ongoing research and advancements in drug delivery methods could further enhance its effectiveness.
9
We observed that vitamin E succinate (VES) has the potential to serve as a tool for fighting cancer, particularly by targeting a protein called fat mass and obesity-associated protein (FTO), which plays a role in tumor growth. This study highlights how VES can act as a degrader of FTO, leading to its suppression, thereby hindering tumor progression and enhancing the effectiveness of immunotherapy.
When VES binds to both FTO and an associated protein called DTX2, it boosts the interaction between them. This ultimately promotes the process that marks FTO for degradation. In animal models, treatment with VES resulted in reduced tumor size and a significant improvement in the immune response against tumors, suggesting a promising avenue for enhancing cancer treatment strategies.
Furthermore, reducing FTO levels increased the methylation of a specific gene, LIF, involved in regulating immune responses, which allowed melanoma cells to become more susceptible to T cell attacks. Overall, these findings shed light on how VES not only degrades FTO but also holds the potential to improve outcomes for patients undergoing cancer therapies.
When VES binds to both FTO and an associated protein called DTX2, it boosts the interaction between them. This ultimately promotes the process that marks FTO for degradation. In animal models, treatment with VES resulted in reduced tumor size and a significant improvement in the immune response against tumors, suggesting a promising avenue for enhancing cancer treatment strategies.
Furthermore, reducing FTO levels increased the methylation of a specific gene, LIF, involved in regulating immune responses, which allowed melanoma cells to become more susceptible to T cell attacks. Overall, these findings shed light on how VES not only degrades FTO but also holds the potential to improve outcomes for patients undergoing cancer therapies.
7
We explored the relationship between dietary intake and the incidence of digestive system cancers, focusing specifically on vitamin E's impact. The study comprised a vast group of over 30,000 adults, gathered through the National Health and Nutrition Examination Survey, covering ten years of data from 2007 to 2018. Interestingly, our findings suggested that vitamin E intake negatively related to the development of hepatocellular carcinoma, a type of liver cancer.
While these results indicate a potentially protective effect of vitamin E concerning this specific cancer type, it’s important to note that the overall associations with other types of digestive cancers were less clear. We found no remarkable correlations between vitamin E and other digestive cancers, emphasizing the complexity of dietary influences on cancer risks. More research is essential to fully untangle these relationships and validate our findings further.
While these results indicate a potentially protective effect of vitamin E concerning this specific cancer type, it’s important to note that the overall associations with other types of digestive cancers were less clear. We found no remarkable correlations between vitamin E and other digestive cancers, emphasizing the complexity of dietary influences on cancer risks. More research is essential to fully untangle these relationships and validate our findings further.
9
Vitamin E enhances cancer treatment
In our exploration of breast cancer treatments, we investigated how nanoparticles infused with vitamin E could effectively deliver cancer medications. Our study specifically focused on drug-resistant HER2-positive breast cancer, which is challenging to treat due to its tendency to develop resistance to standard therapies.
We developed nanoparticles from human serum albumin linked with vitamin E, designed to encapsulate and deliver targeted cancer drugs. Through sophisticated methods, including infrared spectroscopy and cell viability assays, we confirmed that the nanoparticles efficiently bound the drugs and released them over time.
Our results revealed that combining these vitamin E-laden nanoparticles—specifically Lapatinib and Letrozole—in a carefully designed ratio led to a substantial reduction in tumor growth. This combination not only outperformed individual treatments but also proved effective in drug-resistant cell lines, showcasing the potential of vitamin E as a vehicle for enhancing cancer therapy.
Overall, while the study highlighted the promising role of vitamin E in this innovative drug delivery approach, it primarily emphasized the combined effects of the therapies rather than isolating vitamin E's impact alone.
We developed nanoparticles from human serum albumin linked with vitamin E, designed to encapsulate and deliver targeted cancer drugs. Through sophisticated methods, including infrared spectroscopy and cell viability assays, we confirmed that the nanoparticles efficiently bound the drugs and released them over time.
Our results revealed that combining these vitamin E-laden nanoparticles—specifically Lapatinib and Letrozole—in a carefully designed ratio led to a substantial reduction in tumor growth. This combination not only outperformed individual treatments but also proved effective in drug-resistant cell lines, showcasing the potential of vitamin E as a vehicle for enhancing cancer therapy.
Overall, while the study highlighted the promising role of vitamin E in this innovative drug delivery approach, it primarily emphasized the combined effects of the therapies rather than isolating vitamin E's impact alone.
References
- Es-Sai B, Wahnou H, Benayad S, Rabbaa S, Laaziouez Y, et al. Gamma-Tocopherol: A Comprehensive Review of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties. Molecules. 2025;30. 10.3390/molecules30030653
- Qin X, Ge L, Wu S, Li W. Association of dietary intake with cancer of the digestive system: a cross-sectional study. Front Nutr. 2025;12:1539401. 10.3389/fnut.2025.1539401
- Shan X, Cai Y, Zhu B, Sun X, Zhou L, et al. Computer-Aided Design of Self-Assembled Nanoparticles to Enhance Cancer Chemoimmunotherapy via Dual-Modulation Strategy. Adv Healthc Mater. 2025. 10.1002/adhm.202404261
- Kadhim AH, El Arbi M, Muhammed HA. Vitamin E improves the reproductive system of male rats exposed to busulfan chemotherapy. Cell Mol Biol (Noisy-le-grand). 2025;70:175. 10.14715/cmb/2024.70.12.24
- Palencia-Campos A, Ruiz-Cañas L, Abal-Sanisidro M, López-Gil JC, Batres-Ramos S, et al. Reprogramming tumor-associated macrophages with lipid nanosystems reduces PDAC tumor burden and liver metastasis. J Nanobiotechnology. 2024;22:795. 10.1186/s12951-024-03010-5
- Cheng X, Cheng L, He J, Wang Y, Lin X, et al. The Mediating Role of Oxidative Stress on the Association Between Oxidative Balance Score and Cancer-Related Cognitive Impairment in Lung Cancer Patients: A Cross-Sectional Study. Nutrients. 2024;16. 10.3390/nu16234090
- Cui YH, Wei J, Fan H, Li W, Zhao L, et al. Targeting DTX2/UFD1-mediated FTO degradation to regulate antitumor immunity. Proc Natl Acad Sci U S A. 2024;121:e2407910121. 10.1073/pnas.2407910121
- Zhang W, Song L, Zhou Y, Sun J, Li C, et al. Study on the inhibition of non-small cell lung cancer mediated by chitosan-based gene carrier delivering STAT3-shRNA. Int J Biol Macromol. 2025;284:138211. 10.1016/j.ijbiomac.2024.138211
- Are V, Das S, P S S, Biswas S. Combination therapy of Lapatinib/Letrozole-based protein-vitamin nanoparticles to enhance the therapeutic effectiveness in drug-resistant breast cancer. Colloids Surf B Biointerfaces. 2025;247:114399. 10.1016/j.colsurfb.2024.114399
- Wen XY, Cao MM, Zhang ZY, Xie N, Wei ZY, et al. [The role of endoplasmic reticulum IP(3)R calcium channel in vitamin E succinate induced autophagy of human gastric cancer cell]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2025;43:180. 10.3760/cma.j.cn121094-20240125-00037
- Satapathy D, Dutta TK, Chatterjee A, Yadav SK, Dutta S, et al. Ameliorating arsenic toxicity in young goats: assessing vitamin E and Saccharomyces cerevisiae on feed intake, carcass quality, mineral profiles in tissues and impending health risks to humans. Environ Geochem Health. 2025;47:141. 10.1007/s10653-025-02439-3
- Paganini V, Cesari A, Tampucci S, Chetoni P, Burgalassi S, et al. Nanostructured Strategies for Melanoma Treatment-Part I: Design and Optimization of Curcumin-Loaded Micelles for Enhanced Anticancer Activity. Pharmaceuticals (Basel). 2025;18. 10.3390/ph18030327
- Onali T, Slabá H, Jian C, Koivumäki T, Päivärinta E, et al. Berry supplementation in healthy volunteers modulates gut microbiota, increases fecal polyphenol metabolites and reduces viability of colon cancer cells exposed to fecal water- a randomized controlled trial. J Nutr Biochem. 2025. 10.1016/j.jnutbio.2025.109906
- Falsetti I, Palmini G, Zonefrati R, Vasa K, Donati S, et al. Antiproliferative Role of Natural and Semi-Synthetic Tocopherols on Colorectal Cancer Cells Overexpressing the Estrogen Receptor β. Int J Mol Sci. 2025;26. 10.3390/ijms26052305
