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Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
1 g (1,000 mg)
1111%
Citrus Bioflavonoid Complex
100 mg
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Rutin Powder (from Sophora japonica Flower Bud)
25 mg
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The product is found useful for the following medical conditions
Common Cold
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.4
USERS' SCORE
Excellent
Based on 122 Reviews
9
8
Vitamin C reduces cold severity
Vitamin C reduces the severity of common colds: a meta-analysis.
Most Relevant Research
We explored how vitamin C affects the severity of common colds through a comprehensive review of available studies. By including only randomized, placebo-controlled trials where participants received at least 1 gram of vitamin C daily, we aimed to investigate both the overall duration of colds and the intensity of symptoms experienced.
Our analysis found that vitamin C significantly reduced the severity of cold symptoms by about 15%. Interestingly, it appears that the benefits are more pronounced for those experiencing severe symptoms compared to mild ones. In specific comparisons, vitamin C didn’t substantially affect the duration of mild symptoms but had a notable impact on how long severe symptoms lasted.
This insight is crucial, as the common cold often leads to absenteeism at work and school, with more severe symptoms playing a key role in this setback. By highlighting vitamin C's greater effectiveness against intense cold symptoms, we suggest that future research should continue to look into how this vitamin can be utilized in managing cold severity.
Our analysis found that vitamin C significantly reduced the severity of cold symptoms by about 15%. Interestingly, it appears that the benefits are more pronounced for those experiencing severe symptoms compared to mild ones. In specific comparisons, vitamin C didn’t substantially affect the duration of mild symptoms but had a notable impact on how long severe symptoms lasted.
This insight is crucial, as the common cold often leads to absenteeism at work and school, with more severe symptoms playing a key role in this setback. By highlighting vitamin C's greater effectiveness against intense cold symptoms, we suggest that future research should continue to look into how this vitamin can be utilized in managing cold severity.
9.5
Supports recovery
Most Useful Review
It’s essential for connective tissue and immunity! Due to the coronavirus pandemic, I bought this supplement to support my immune system and improve collagen absorption. This vitamin is well-known for its crucial role in combatting the common cold.
Autoimmune Disorder
SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8
USERS' SCORE
Good
Based on 16 Reviews
8.9
9
Vitamin C impacts autoimmune response
Ascorbic acid alleviates rheumatoid arthritis by inhibiting the production of autoantibodies.
Most Relevant Research
We investigated how vitamin C, also known as ascorbic acid, might impact autoimmune disorders like rheumatoid arthritis. Through a study involving a mouse model of collagen-induced arthritis, we administered vitamin C or a placebo solution and observed the effects on the immune response and disease progression.
Notably, the research showed that mice given vitamin C experienced a significant delay in the onset of arthritis and a reduction in disease severity. This suggests that vitamin C can play a critical role in managing autoimmune conditions by minimizing the production of autoantibodies, which are harmful antibodies that mistakenly attack the body's tissues.
Our findings revealed that vitamin C reduced the number of plasma cells and decreased antibody production in response to immunization. This indicates that vitamin C influences the immune system's response at a cellular level, helping to prevent the emergence of autoreactive plasma cells. We also discovered that the mechanism behind this effect involved inhibiting the Stat3 signaling pathway, leading to less activation of autoreactive immune components.
Ultimately, these results highlight the potential of vitamin C not just as a nutrient, but as a strategic tool in managing autoimmune disorders. By simply supplementing with vitamin C, there may be a way to intervene positively in the progression of diseases like rheumatoid arthritis.
Notably, the research showed that mice given vitamin C experienced a significant delay in the onset of arthritis and a reduction in disease severity. This suggests that vitamin C can play a critical role in managing autoimmune conditions by minimizing the production of autoantibodies, which are harmful antibodies that mistakenly attack the body's tissues.
Our findings revealed that vitamin C reduced the number of plasma cells and decreased antibody production in response to immunization. This indicates that vitamin C influences the immune system's response at a cellular level, helping to prevent the emergence of autoreactive plasma cells. We also discovered that the mechanism behind this effect involved inhibiting the Stat3 signaling pathway, leading to less activation of autoreactive immune components.
Ultimately, these results highlight the potential of vitamin C not just as a nutrient, but as a strategic tool in managing autoimmune disorders. By simply supplementing with vitamin C, there may be a way to intervene positively in the progression of diseases like rheumatoid arthritis.
9.5
Nails improved
Most Useful Review
Vitamin D3 significantly helped me. After my second birth, I experienced problems with my nails and a lack of energy. Following my sister's advice, I started taking this vitamin (one tablet every two days), and within a week, I felt energised. I was able to clean my whole flat and engage with my children more. Even with sun exposure, I wasn't feeling well, but after a month of taking Vitamin D3, the improvements were noticeable. My nails are now smoother!
Cold Sores
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 23 Reviews
8.9
9
Vitamin C alleviates cold sores
Topical treatment of recurrent mucocutaneous herpes with ascorbic acid-containing solution.
Most Relevant Research
We investigated how an ascorbic acid-based solution could help treat recurrent cold sores, also known as mucocutaneous herpes. This study was carefully designed as a randomized, double-blind, placebo-controlled trial, which helps ensure the results are reliable and trustworthy.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
9.5
Quick recovery
Most Useful Review
This helps enormously with colds. I take it at the first signs, and it’s an excellent remedy!
Chronic Cough
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 7 Reviews
8.8
9.5
Fast outcome
Most Useful Review
The quality of this vitamin C is exceptional. It has helped me alleviate sore throat, runny nose, and chronic cough efficiently. It is well absorbed, doesn't cause heartburn, and works rapidly.
Allergies
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 12 Reviews
8.7
8
Pleuran and Vitamin C aid asthma
Beneficial effects of pleuran on asthma control and respiratory tract-infection frequency in children with perennial asthma.
Most Relevant Research
We conducted a thorough evaluation of how vitamin C, when combined with pleuran, impacts asthma control and respiratory issues in children suffering from perennial asthma. The study was meticulously designed as a double-blind, placebo-controlled trial involving 230 children aged 7 to 17 years. This means that neither the participants nor the researchers knew who was receiving the active treatment or the placebo, ensuring the findings were reliable.
The results were promising, especially for children under 12 years. They showed significant improvements in asthma control compared to those receiving only the placebo treatment. Meanwhile, older children (12 years and above) experienced fewer respiratory infections with the combination treatment. Overall, by the end of the 48 weeks, a majority of children on the pleuran and vitamin C treatment reported better asthma control compared to those on the placebo.
While the combination of pleuran and vitamin C was indeed beneficial for managing asthma, we must note that the study did not specifically isolate the effect of vitamin C alone on allergies or asthma. Thus, it is hard to draw definitive conclusions about vitamin C's effectiveness independently from pleuran. However, the approach suggested that using these supplements together could offer a helpful boost in managing asthma symptoms.
The results were promising, especially for children under 12 years. They showed significant improvements in asthma control compared to those receiving only the placebo treatment. Meanwhile, older children (12 years and above) experienced fewer respiratory infections with the combination treatment. Overall, by the end of the 48 weeks, a majority of children on the pleuran and vitamin C treatment reported better asthma control compared to those on the placebo.
While the combination of pleuran and vitamin C was indeed beneficial for managing asthma, we must note that the study did not specifically isolate the effect of vitamin C alone on allergies or asthma. Thus, it is hard to draw definitive conclusions about vitamin C's effectiveness independently from pleuran. However, the approach suggested that using these supplements together could offer a helpful boost in managing asthma symptoms.
9.5
Cold prevention
Most Useful Review
High dosage of vitamin C as ascorbic acid (1000 mg) with added citrus bioflavonoids and rutin enhances its effect. I usually purchase this before the cold season and take 1000 mg daily at the first signs of illness. This dosage helps alleviate cold symptoms but should not be taken daily for more than 2-3 weeks. A continuous dosage should be between 250-500 mg to avoid issues.
Blood Clot
SCIENTIFIC SCORE
Questionable
Based on 6 Researches
6.7
USERS' SCORE
Good
Based on 10 Reviews
8.7
9
Vitamin C enhances blood clotting
Ascorbic acid improves thrombotic function of platelets during living donor liver transplantation by modulating the function of the E3 ubiquitin ligases c-Cbl and Cbl-b.
Most Relevant Research
We sought to understand how ascorbic acid, commonly known as vitamin C, impacts blood clotting during living donor liver transplantation (LDLT). In our study, we analyzed blood samples from 21 recipients before and after their surgeries.
We employed a well-structured approach, using rotational thromboelastography (TEG) and western blot analysis to scrutinize fibrinolysis and the functionality of specific proteins involved in clotting. Blood samples were tested in three distinct groups, one receiving vitamin C, to see its effects on clot rigidity and fibrinolysis.
Our findings revealed that ascorbic acid notably reduced fibrinolysis, which refers to the breakdown of blood clots, and improved the rigidity of the clots formed. Additionally, we observed that levels of a protein called Cbl-b were higher in those receiving vitamin C, while another protein, c-Cbl, showed reduced phosphorylation. These functional changes might explain how vitamin C supports better clotting during surgeries.
This study indicates that vitamin C could be a beneficial treatment to consider during LDLT to manage hyperfibrinolysis, thus promoting better outcomes for patients undergoing these complex procedures.
We employed a well-structured approach, using rotational thromboelastography (TEG) and western blot analysis to scrutinize fibrinolysis and the functionality of specific proteins involved in clotting. Blood samples were tested in three distinct groups, one receiving vitamin C, to see its effects on clot rigidity and fibrinolysis.
Our findings revealed that ascorbic acid notably reduced fibrinolysis, which refers to the breakdown of blood clots, and improved the rigidity of the clots formed. Additionally, we observed that levels of a protein called Cbl-b were higher in those receiving vitamin C, while another protein, c-Cbl, showed reduced phosphorylation. These functional changes might explain how vitamin C supports better clotting during surgeries.
This study indicates that vitamin C could be a beneficial treatment to consider during LDLT to manage hyperfibrinolysis, thus promoting better outcomes for patients undergoing these complex procedures.
9.5
Improved blood vessels
Most Useful Review
These vitamins are excellent for collagen formation, which benefits the skin, ligaments, and blood vessels. My facial inflammation has subsided, and my complexion improved. My mother's leg pain has stopped, and vitamin C has strengthened my bleeding gums. Healing of wounds and bruises has accelerated too.
Hypothyroidism
SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8
USERS' SCORE
Good
Based on 2 Reviews
8.7
7
Vitamin C may lower hypothyroidism risk
Association between total vitamin C intake and hypothyroidism among Hashimoto thyroiditis: National Health and Nutrition Examination Survey, 2007-2012.
Most Relevant Research
We set out to examine how total vitamin C intake might influence hypothyroidism in individuals with Hashimoto thyroiditis, using data from the National Health and Nutrition Examination Survey conducted between 2007 and 2012. Our study utilized multivariate logistic regression and restricted cubic spline analyses to uncover possible associations.
What we found was quite intriguing. There was a clear negative linear relationship between total vitamin C intake and hypothyroidism. Specifically, participants who consumed higher amounts of vitamin C had a significantly lower likelihood of developing hypothyroidism. Those in the top quartile of vitamin C intake were about 60% less likely to have hypothyroidism compared to those in the lowest quartile.
This pattern remained consistent across different age groups and sexes, further emphasizing the potential benefits of vitamin C for individuals with Hashimoto's. Our findings suggest that increasing vitamin C intake may be a simple and effective strategy for reducing the risk of hypothyroidism in those affected. The data indicates that consuming between 4.57 and 1258.9 mg/day of vitamin C could be beneficial.
Overall, our research adds to the understanding of how antioxidants like vitamin C can play a role in thyroid health, encouraging us to consider dietary sources of this vital vitamin for those managing Hashimoto's thyroiditis.
What we found was quite intriguing. There was a clear negative linear relationship between total vitamin C intake and hypothyroidism. Specifically, participants who consumed higher amounts of vitamin C had a significantly lower likelihood of developing hypothyroidism. Those in the top quartile of vitamin C intake were about 60% less likely to have hypothyroidism compared to those in the lowest quartile.
This pattern remained consistent across different age groups and sexes, further emphasizing the potential benefits of vitamin C for individuals with Hashimoto's. Our findings suggest that increasing vitamin C intake may be a simple and effective strategy for reducing the risk of hypothyroidism in those affected. The data indicates that consuming between 4.57 and 1258.9 mg/day of vitamin C could be beneficial.
Overall, our research adds to the understanding of how antioxidants like vitamin C can play a role in thyroid health, encouraging us to consider dietary sources of this vital vitamin for those managing Hashimoto's thyroiditis.
9.5
Increased energy
Most Useful Review
Excellent! I really liked the vitamin D from this manufacturer; I feel energised and active from early morning to late evening, and sometimes even at night. The apathy associated with hypothyroidism has vanished! I have a large jar that will last me a long time, and the small gelatin capsules are convenient to take. I highly recommend it! đź‘Ť
Pneumonia
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.7
9.5
Improved recovery speed
Most Useful Review
After my dad became seriously ill with pneumonia, he was hospitalised. The doctor recommended vitamin D, C, and zinc, but we couldn't find the correct dosage locally, so I ordered it here. Within three days of taking the vitamins, my dad began to improve — his temperature fell, he regained his colour, and his breathing became easier. The doctor was astonished at his rapid recovery for his age and acknowledged that the vitamins certainly played a role.
Chronic Fatigue Syndrome
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7
USERS' SCORE
Good
Based on 17 Reviews
8.6
7
Vitamin C aids immune function
The clinical course of interstitial pneumonia alias chronic fatigue syndrome under the control of megadose vitamin C infusion system with dehydroepiandrosterone-cortisol annex.
Most Relevant Research
We examined how a combination of megadose vitamin C infusions and other treatments might help manage chronic fatigue syndrome, particularly in the context of interstitial pneumonia. Our findings were based on nearly a decade of treating patients, allowing us to gather valuable insights.
We observed that the long-term use of this treatment system significantly reduced the risk of pneumonia recurrence. It also appeared to help prevent the emergence of certain cancers in older patients suffering from interstitial pneumonia. Surprisingly, we found a link between interstitial pneumonia and an increased risk of depression, likely driven by prolonged glucocorticoid use.
While some patients showed promise under this treatment, those battling both interstitial pneumonia and depression responded less favorably. We suggested that increasing the amount of dehydroepiandrosterone in the treatment could be beneficial. Throughout our experience, we noted that the characteristics of chronic fatigue syndrome align closely with those of interstitial pneumonia, arguing against the notion that they should be viewed as separate conditions.
Overall, our approach not only alleviated inflammation but did not suppress the fibrotic processes in the long run. We made modifications to the treatment to lower the risks of vascular complications. The main strength of our treatment lies in creating a hormonal environment that helps tackle immune deficiencies using vitamin C, which faces lower resistance in the body compared to steroid treatments.
We observed that the long-term use of this treatment system significantly reduced the risk of pneumonia recurrence. It also appeared to help prevent the emergence of certain cancers in older patients suffering from interstitial pneumonia. Surprisingly, we found a link between interstitial pneumonia and an increased risk of depression, likely driven by prolonged glucocorticoid use.
While some patients showed promise under this treatment, those battling both interstitial pneumonia and depression responded less favorably. We suggested that increasing the amount of dehydroepiandrosterone in the treatment could be beneficial. Throughout our experience, we noted that the characteristics of chronic fatigue syndrome align closely with those of interstitial pneumonia, arguing against the notion that they should be viewed as separate conditions.
Overall, our approach not only alleviated inflammation but did not suppress the fibrotic processes in the long run. We made modifications to the treatment to lower the risks of vascular complications. The main strength of our treatment lies in creating a hormonal environment that helps tackle immune deficiencies using vitamin C, which faces lower resistance in the body compared to steroid treatments.
9.5
Alleviates withdrawal symptoms
Most Useful Review
I love that this product includes bioflavonoids, as they enhance the benefits of vitamin C. I'm using it to manage withdrawal symptoms from benzodiazepines, improve adrenal fatigue, and provide an antioxidant effect. It has helped me immensely. I take 5g a day in divided doses.
Gout
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 1 Review
8.6
8
Dietary Vitamin C and Gout
Association between dietary vitamin C intake and gout among American adults.
Most Relevant Research
We investigated the potential relationship between dietary vitamin C intake and gout among American adults using data from the National Health and Nutrition Examination Survey conducted between 2013 and 2018. This study included participants over the age of 20 and looked at various factors, including the incidence of gout and levels of vitamin C intake.
Our findings revealed that 5% of the 12,589 participants reported experiencing gout. Interestingly, those consuming higher amounts of dietary vitamin C showed a lower likelihood of developing gout. Specifically, individuals in the highest intake group had an odds ratio of 0.77 for having gout, suggesting an inverse relationship between vitamin C intake and gout occurrence.
We noted that this relationship exhibited an L-shaped pattern, indicating that increased vitamin C consumption may be linked to reduced gout risk, particularly among different sex groups. However, when we examined vitamin C supplements, no significant association with gout was observed. Overall, our research highlights the potential benefits of dietary vitamin C in preventing gout, while underscoring the need for more focused studies in this area.
Our findings revealed that 5% of the 12,589 participants reported experiencing gout. Interestingly, those consuming higher amounts of dietary vitamin C showed a lower likelihood of developing gout. Specifically, individuals in the highest intake group had an odds ratio of 0.77 for having gout, suggesting an inverse relationship between vitamin C intake and gout occurrence.
We noted that this relationship exhibited an L-shaped pattern, indicating that increased vitamin C consumption may be linked to reduced gout risk, particularly among different sex groups. However, when we examined vitamin C supplements, no significant association with gout was observed. Overall, our research highlights the potential benefits of dietary vitamin C in preventing gout, while underscoring the need for more focused studies in this area.
9.5
Effective pain relief
Most Useful Review
I found these soft, easy-to-swallow capsules to be the best remedy for gout. The effects of vitamin C can be felt within weeks, especially during a gout attack, as it eases pain and is proven to reduce uric acid levels when taken at 500 mg or more for one to two months.
Lung Cancer
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.9
USERS' SCORE
Good
Based on 3 Reviews
8.6
9
Vitamin C reduces lung cancer spread
Vitamin C Inhibited Pulmonary Metastasis through Activating Nrf2/HO-1 Pathway.
Most Relevant Research
We explored the effects of vitamin C on lung cancer, particularly its ability to inhibit pulmonary metastasis—meaning the spread of cancer to the lungs. Using an H22 pulmonary metastasis mouse model, we observed that vitamin C administration, both intraperitoneally and orally, showed promising results.
Through the research, we found that intraperitoneal injections of vitamin C led to an increase in crucial proteins like Nrf2 and HO-1, which are known to help combat cancer. This process resulted in increased cell death in cancer cells through DNA damage and apoptosis, mimicking the effects seen when using pro-oxidant treatments in cells lacking the p53 protein—a critical tumor suppressor.
Furthermore, oral vitamin C not only activated these protective pathways but also spurred the expression of p53 in healthy tumor cells, showcasing its potential as an antimetastatic agent. We noted that vitamin C reduced the proliferation and migration of lung cancer cells while being gentler on normal cells, suggesting a safer therapeutic profile.
Overall, this study highlights vitamin C's dual role in both bolstering the body's defenses against cancer and directly inhibiting the spread of lung cancer, paving the way for its consideration in clinical treatments for pulmonary metastasis.
Through the research, we found that intraperitoneal injections of vitamin C led to an increase in crucial proteins like Nrf2 and HO-1, which are known to help combat cancer. This process resulted in increased cell death in cancer cells through DNA damage and apoptosis, mimicking the effects seen when using pro-oxidant treatments in cells lacking the p53 protein—a critical tumor suppressor.
Furthermore, oral vitamin C not only activated these protective pathways but also spurred the expression of p53 in healthy tumor cells, showcasing its potential as an antimetastatic agent. We noted that vitamin C reduced the proliferation and migration of lung cancer cells while being gentler on normal cells, suggesting a safer therapeutic profile.
Overall, this study highlights vitamin C's dual role in both bolstering the body's defenses against cancer and directly inhibiting the spread of lung cancer, paving the way for its consideration in clinical treatments for pulmonary metastasis.
9.5
Effective against cancer
Most Useful Review
Affordable and highly effective, particularly for lung cancer therapy. Vitamin C is ineffective without bioflavonoids, which many people overlook, and producers often exploit. However, these capsules have proven very beneficial in combating lung cancer, effectively disrupting cancer cells.
Tinnitus
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Pain relief
Most Useful Review
Amazing. It helps me manage significant pain and offers relief for my almost non-existent tinnitus. Can't live without it!
Back Pain
SCIENTIFIC SCORE
Questionable
Based on 4 Researches
5.3
USERS' SCORE
Good
Based on 2 Reviews
8.5
4
Vitamin C's limited impact on pain
The Efficacy of Vitamin C on Postoperative Outcomes after Posterior Lumbar Interbody Fusion: A Randomized, Placebo-Controlled Trial.
Most Relevant Research
We conducted a year-long study to investigate the effects of vitamin C on postoperative pain and recovery after a specific type of spine surgery known as posterior lumbar interbody fusion (PLIF). In this randomized, placebo-controlled trial, we worked with 123 patients, dividing them into two groups: one receiving vitamin C and the other a placebo.
Our main focus was to see how vitamin C influenced lower back pain measured by a visual analogue scale. While we found that there was no significant difference in pain levels at the one-year mark between the two groups, there was a silver lining. We observed that vitamin C appeared to enhance functional improvement, especially within the first three months after surgery.
So, while vitamin C didn’t seem to directly reduce pain intensity after surgery, it could play a role in supporting early recovery and everyday function. This finding may encourage further exploration into vitamin C's potential benefits in postoperative care for patients undergoing spine surgeries.
Our main focus was to see how vitamin C influenced lower back pain measured by a visual analogue scale. While we found that there was no significant difference in pain levels at the one-year mark between the two groups, there was a silver lining. We observed that vitamin C appeared to enhance functional improvement, especially within the first three months after surgery.
So, while vitamin C didn’t seem to directly reduce pain intensity after surgery, it could play a role in supporting early recovery and everyday function. This finding may encourage further exploration into vitamin C's potential benefits in postoperative care for patients undergoing spine surgeries.
9.5
Effective treatment noted
Most Useful Review
During the epidemic, I avoided visiting the dentist. When I experienced bleeding gums or mouth sores, I took high doses of Vitamin C every hour or two. Within a day or two, the pain subsided significantly. For over three years, I’ve been taking around seven high-dose Vitamin C capsules daily and my overall health is excellent. I rarely need any medication and haven’t caught the flu.
Heart Disease
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.8
USERS' SCORE
Good
Based on 1 Review
8.5
7
Vitamin C's uncertain heart benefits
Role of Vitamins in Cardiovascular Health: Know Your Facts - Part 1.
Most Relevant Research
We aimed to understand the role of vitamin C in heart disease and its potential cardioprotective effects. Vitamin C is renowned for its antioxidant properties, which means it fights off harmful substances in our body, potentially reducing the risk of heart issues.
Our analysis revealed that vitamin C could play a meaningful role in supporting cardiovascular health. While the evidence is promising, it is important to be cautious, as clinical studies have shown mixed results regarding its effectiveness.
So, while vitamin C might contribute positively to heart health, more solid evidence is required to fully confirm these effects. Overall, we learned that while there are positive indicators, we should be careful about over-relying on vitamin C as a sole preventive measure for heart disease.
Our analysis revealed that vitamin C could play a meaningful role in supporting cardiovascular health. While the evidence is promising, it is important to be cautious, as clinical studies have shown mixed results regarding its effectiveness.
So, while vitamin C might contribute positively to heart health, more solid evidence is required to fully confirm these effects. Overall, we learned that while there are positive indicators, we should be careful about over-relying on vitamin C as a sole preventive measure for heart disease.
8.8
Improved heart health
Most Useful Review
Vitamin C has greatly benefitted my sister, who suffers from stomach issues and high acidity. We sourced this product based on its positive reviews and our doctor's approval. I’ve been taking vitamin C for some time; it acts as a good antioxidant. My sister's health has noticeably improved, especially her immune system. Although the capsules are large, they are not difficult to swallow. This vitamin contributes to protecting heart health and managing blood pressure and cholesterol levels. The packaging is reliable, and the quality is satisfactory.
Knee Pain
SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.9
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Vitamin C for knee pain relief
Skeletal manifestations of scurvy: a case report from dubai.
Most Relevant Research
We observed an intriguing case involving a 4.5-year-old boy who developed significant knee pain due to a rare nutritional deficiency, scurvy. This condition stemmed from his exclusive intake of meat over the past two years, resulting in skeletal issues and inflammation in multiple joints, including his knees.
Upon examination, the child exhibited several symptoms, including pain, swelling, and an inability to walk. Standard blood tests primarily indicated anemia, but X-rays revealed alarming conditions related to scurvy, such as delayed bone age and severe osteopenia. This alarming picture led us to the conclusion that vitamin C deficiency was the underlying culprit behind his knee pain and skeletal issues.
After initiating vitamin C therapy, we noted a remarkable reduction in pain and swelling over the next two months. The child’s condition improved significantly, allowing him to walk again, and follow-up X-rays confirmed the positive changes in his bone health. This case clearly illustrates how vitamin C can effectively alleviate knee pain related to scurvy and reinforces the importance of proper nutrition for overall skeletal health.
Upon examination, the child exhibited several symptoms, including pain, swelling, and an inability to walk. Standard blood tests primarily indicated anemia, but X-rays revealed alarming conditions related to scurvy, such as delayed bone age and severe osteopenia. This alarming picture led us to the conclusion that vitamin C deficiency was the underlying culprit behind his knee pain and skeletal issues.
After initiating vitamin C therapy, we noted a remarkable reduction in pain and swelling over the next two months. The child’s condition improved significantly, allowing him to walk again, and follow-up X-rays confirmed the positive changes in his bone health. This case clearly illustrates how vitamin C can effectively alleviate knee pain related to scurvy and reinforces the importance of proper nutrition for overall skeletal health.
8.8
Pain relief achieved
Most Useful Review
During the epidemic, I did not visit the dentist. When I experienced bleeding gums or mouth sores, I took high doses of vitamin C every couple of hours. Within one or two days, the pain subsided. I have been taking around seven capsules of high-dose vitamin C daily for over three years, and I feel well. I do not require any other medication and have not had the flu.
Leg Cramps
SCIENTIFIC SCORE
Questionable
Based on 1 Research
5
USERS' SCORE
Good
Based on 5 Reviews
8.5
5
Leg cramps treatment comparison
Calcium and magnesium status in pregnant women. A comparison between treatment with calcium and vitamin C in pregnant women with leg cramps.
Most Relevant Research
We explored the effects of vitamin C on leg cramps in a group of 60 pregnant women through a double-blind trial. Participants received either calcium or vitamin C (1 g twice daily) as treatment. Our observations revealed that there was no significant difference in clinical improvement between the two treatment groups.
Notably, 14 patients experienced complete relief from symptoms, while 27 reported significant improvement regardless of which treatment they received. Unfortunately, 17 participants found their symptoms unchanged, and only two noticed an increase in leg cramps during the treatment period.
Throughout the study, we measured serum levels of total and ionized calcium, total magnesium, and albumin, but these parameters did not show significant changes in either treatment group. We also didn’t identify any biochemical differences when comparing the effectiveness of vitamin C and calcium for alleviating cramps.
Ultimately, our findings suggest that vitamin C may not be an effective solution for leg cramps in pregnant women, as both treatments yielded similar results with minimal biochemical changes.
Notably, 14 patients experienced complete relief from symptoms, while 27 reported significant improvement regardless of which treatment they received. Unfortunately, 17 participants found their symptoms unchanged, and only two noticed an increase in leg cramps during the treatment period.
Throughout the study, we measured serum levels of total and ionized calcium, total magnesium, and albumin, but these parameters did not show significant changes in either treatment group. We also didn’t identify any biochemical differences when comparing the effectiveness of vitamin C and calcium for alleviating cramps.
Ultimately, our findings suggest that vitamin C may not be an effective solution for leg cramps in pregnant women, as both treatments yielded similar results with minimal biochemical changes.
9.5
Improved skin condition
Most Useful Review
These vitamins are excellent for collagen production, benefiting skin, ligaments, and blood vessels. My facial inflammation has resolved and my mother's leg cramps no longer trouble her. Vitamin C has also strengthened my teeth and sped up healing. I have reduced sweet consumption as well.
Liver Disease
SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.9
USERS' SCORE
Good
Based on 3 Reviews
8.5
9
Vitamin C reduces liver injury
The Effect of Ascorbic Acid on Hepatic Ischaemia-Reperfusion Injury in Wistar Rats: An Experimental Study.
Most Relevant Research
We evaluated how vitamin C, also known as ascorbic acid, can help protect the liver during procedures that temporarily cut off blood flow—a process known as ischaemia followed by reperfusion. In this study, we used thirty-six male Wistar rats, split into control groups and experimental ones. Each group received the same total dose of vitamin C, administered at different times: either before the ischaemia, before the reperfusion, or both.
Our findings showed that the animals given vitamin C before both the ischaemia and reperfusion had improved outcomes. They had lower levels of liver enzymes, indicating less liver damage, and showed reduced inflammation. Additionally, their portal blood flow was better when compared to the other groups. Overall, our results suggest that administering vitamin C at specific times can significantly reduce liver injury associated with ischaemia-reperfusion.
This study highlights the potential of vitamin C as a protective agent in situations where liver damage is a concern during surgeries or treatments involving blood flow disruption.
Our findings showed that the animals given vitamin C before both the ischaemia and reperfusion had improved outcomes. They had lower levels of liver enzymes, indicating less liver damage, and showed reduced inflammation. Additionally, their portal blood flow was better when compared to the other groups. Overall, our results suggest that administering vitamin C at specific times can significantly reduce liver injury associated with ischaemia-reperfusion.
This study highlights the potential of vitamin C as a protective agent in situations where liver damage is a concern during surgeries or treatments involving blood flow disruption.
9.5
Supporting liver detoxification
Most Useful Review
I take this with iron to enhance absorption, and I notice the benefits during blood tests for ferritin. It's crucial when feeling unwell or chilled. I was thankful to have it during a recent illness, as it assisted in detoxifying and cleansing my liver. Combined with other vitamins, it boosts their effects. I've recommended it to friends, all of whom are pleased.
Cardiovascular Disease
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
USERS' SCORE
Good
Based on 2 Reviews
8.4
7
Vitamin C enhances NK cell proliferation
Proliferation capability of natural killer cells upon cytokines stimulation correlated negatively with serum lactate dehydrogenase level in coronary artery disease patients.
Most Relevant Research
We explored the effects of vitamin C on natural killer (NK) cell activity in patients with coronary artery disease (CAD). Our research involved isolating NK cells from 29 CAD patients and treating them with various stimulatory factors, including ascorbic acid—better known as vitamin C.
What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.
Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.
Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.
Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.
Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
7
Supports cardiovascular health
Most Useful Review
This quantity is substantial as I consumed a lot and bought this much. There are no issues with the ingredients and quality; they are consistent, and the effect is satisfactory. Some inflammations were alleviated. Vitamin C is a water-soluble vitamin, crucial for decomposing skin melanin, thus preventing pigmentation and treating melasma. It assists with collagen synthesis, promotes wound healing, and helps with cardiovascular disease.
Pelvic Pain
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.1
9.5
Effective pain relief
Most Useful Review
During the epidemic, I didn’t visit the dentist. When I experienced bleeding gums or mouth sores, I took high doses of vitamin C every couple of hours. Within a day or two, the pain disappeared, and I felt better. I have been consuming around seven vitamin C capsules daily for over three years, and I remain in good health without any medication or flu.
Diarrhea
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6.5
USERS' SCORE
Moderately Good
Based on 15 Reviews
7.4
9
Vitamin C improves diarrheic calf health
Does vitamin C supplementation in milk improve growth and health of diarrheic calves?
Most Relevant Research
We investigated how adding vitamin C to milk influences the growth and health of young calves, particularly those experiencing diarrhea. The study involved 48 Holstein calves, which were sorted into two groups based on their health status: healthy calves and those with diarrhea. Each calf was fed the same amount of pasteurized milk and monitored until they reached 74 days of age.
Calves that received vitamin C showed an impressive increase in weight by weaning—74.3 kg compared to 72.2 kg for those without vitamin C. Additionally, calves treated with vitamin C demonstrated improved blood antioxidant levels, suggesting better overall health. Notably, calves suffering from diarrhea benefitted significantly from the vitamin C, needing fewer days of medication for treatment compared to those who did not receive the supplement.
The research highlights that vitamin C can play a critical role in supporting the health of calves during episodes of diarrhea. This is especially relevant for those that faced even mild cases early in life, as they seemed to gain the most benefits from the supplementation. Overall, it appears that vitamin C can positively impact both growth and health in calves suffering from diarrhea.
Calves that received vitamin C showed an impressive increase in weight by weaning—74.3 kg compared to 72.2 kg for those without vitamin C. Additionally, calves treated with vitamin C demonstrated improved blood antioxidant levels, suggesting better overall health. Notably, calves suffering from diarrhea benefitted significantly from the vitamin C, needing fewer days of medication for treatment compared to those who did not receive the supplement.
The research highlights that vitamin C can play a critical role in supporting the health of calves during episodes of diarrhea. This is especially relevant for those that faced even mild cases early in life, as they seemed to gain the most benefits from the supplementation. Overall, it appears that vitamin C can positively impact both growth and health in calves suffering from diarrhea.
9.5
Quick recovery
Most Useful Review
I order it for the whole family; when someone has a cold, we take 1g every hour. If diarrhoea occurs, we adjust the dosage. This approach helps everyone recover swiftly.
Bone Pain
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.1
9.5
No bone pain
Most Useful Review
During the epidemic, I avoided the dentist. When dealing with bleeding gums or mouth sores, I took a high dose of vitamin C, which alleviated my pain within a day or two. For over three years, I've taken about seven high-dose vitamin C capsules daily. My health has been excellent—I haven't taken any other medication and haven't caught the flu.
Heartburn
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Moderately Good
Based on 20 Reviews
7
8
Vitamin C reduces heartburn symptoms
The safety and efficacy of 2% vitamin C solution spray for relief of mucosal irritation caused by Lugol chromoendoscopy: a multicenter, randomized, double-blind, parallel trial.
Most Relevant Research
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
9.5
No heartburn observed
Most Useful Review
I've just started taking these capsules, which do not cause any heartburn, making them suitable for older individuals or those with stomach issues. The large dose is effective; I feel invigorated, more productive, and my mood has improved. It seems to have enhanced my memory and skin appearance too.
Chest Pain
SCIENTIFIC SCORE
Moderately Effective
Based on 13 Researches
8.3
USERS' SCORE
Medium or Average
Based on 12 Reviews
6.8
9
Vitamin C improves coronary response
Effect of ascorbic acid on endothelial dysfunction of epicardial coronary arteries in chronic smokers assessed by cold pressor testing.
Most Relevant Research
We explored the effects of vitamin C on chest pain in chronic smokers experiencing endothelial dysfunction. In our study, 31 patients, who were undergoing diagnostic catheterization without significant coronary artery issues, participated in a controlled trial. They were given either an IV infusion of 3 grams of ascorbic acid (vitamin C) or a placebo saline solution before undergoing a cold pressor test to assess their coronary artery response.
The results were telling. Smokers typically showed a decrease in luminal area—an indicator of blood flow—during the cold pressor test. However, after infusing vitamin C, this response shifted positively, demonstrating improved blood flow through a vasodilation effect. On the other hand, those who received the placebo did not experience significant changes.
This means that for chronic smokers, acute administration of vitamin C appears to enhance the function of the endothelium, which is vital for proper blood vessel health and managing chest pain. Ultimately, we observed that vitamin C may help prevent the inactivation of nitric oxide, a compound that supports healthy blood flow, and this effect could be crucial for managing cardiovascular health in smokers.
The results were telling. Smokers typically showed a decrease in luminal area—an indicator of blood flow—during the cold pressor test. However, after infusing vitamin C, this response shifted positively, demonstrating improved blood flow through a vasodilation effect. On the other hand, those who received the placebo did not experience significant changes.
This means that for chronic smokers, acute administration of vitamin C appears to enhance the function of the endothelium, which is vital for proper blood vessel health and managing chest pain. Ultimately, we observed that vitamin C may help prevent the inactivation of nitric oxide, a compound that supports healthy blood flow, and this effect could be crucial for managing cardiovascular health in smokers.
9.5
Improves chest symptoms
Most Useful Review
The capsules are large and taste sour. I took them after breakfast with some water to avoid pain, unlike when I took them on an empty stomach. The quantity is excellent, and they wonderfully alleviate my chest pain. After I received the Covid vaccine and felt unwell, this product helped with the fatigue lasting only one day. Additionally, my skin improved significantly, with red acne spots beginning to fade. I recommend it; just remember to keep it in the fridge.
