SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.8
USERS' SCORE
Good
Based on 7 Reviews
8
Supplement Facts
Serving Size: 2 Gummy Supplements
Amount Per Serving
%DV
Calories
15
Total Carbohydrate
3 g
1%†
Total Sugars
3 g
**
Includes 3 g Added Sugars
6%†
Melatonin
5 mg
**
Top Medical Research Studies
9
Melatonin delivery enhances sleep
Silk fibroin microneedles loaded with melatonin for circadian rhythm regulation.
Direct impact on insomnia treatment.
We developed a new way to deliver melatonin for those struggling with insomnia by creating microneedles made from silk fibroin. These tiny needles are designed to improve how the body absorbs melatonin, making it easier for people to get to sleep and stay asleep.
Our research shows that these microneedles can release melatonin steadily over a period of 11 hours. When we tested it on animals, we found that the microneedles maintained stable levels of drug in the bloodstream for up to 8 hours. This is promising news for individuals who may need help with their sleep cycles.
Additionally, the microneedles not only helped regulate sleep but also made a noticeable difference in anxiety levels in insomnia model rats. By improving the disrupted circadian rhythms, melatonin loaded into these microneedles could lead to significant therapeutic benefits.
We believe this innovative approach could enhance patient compliance and provide effective sleep aid for many in need. It’s an exciting development in the field of transdermal drug delivery for improving sleep quality and overcoming insomnia.
Our research shows that these microneedles can release melatonin steadily over a period of 11 hours. When we tested it on animals, we found that the microneedles maintained stable levels of drug in the bloodstream for up to 8 hours. This is promising news for individuals who may need help with their sleep cycles.
Additionally, the microneedles not only helped regulate sleep but also made a noticeable difference in anxiety levels in insomnia model rats. By improving the disrupted circadian rhythms, melatonin loaded into these microneedles could lead to significant therapeutic benefits.
We believe this innovative approach could enhance patient compliance and provide effective sleep aid for many in need. It’s an exciting development in the field of transdermal drug delivery for improving sleep quality and overcoming insomnia.
Read More
8
Melatonin's optimized dosage improves sleep
Optimizing the Time and Dose of Melatonin as a Sleep-Promoting Drug: A Systematic Review of Randomized Controlled Trials and Dose-Response Meta-Analysis.
Significant evidence for dosing benefits
We examined how melatonin, a popular sleep aid, affects insomnia through a thorough review of 26 randomized controlled trials.
Our findings indicate that melatonin can indeed help reduce the time it takes to fall asleep and increase total sleep duration.
However, effectiveness seems to improve with a higher dose of 4 mg taken about three hours before bedtime.
This suggests that adjusting both the timing and dosage may lead to better sleep outcomes compared to commonly used methods.
Our findings indicate that melatonin can indeed help reduce the time it takes to fall asleep and increase total sleep duration.
However, effectiveness seems to improve with a higher dose of 4 mg taken about three hours before bedtime.
This suggests that adjusting both the timing and dosage may lead to better sleep outcomes compared to commonly used methods.
Read More
8
Melatonin improves sleep in ASD
Insomnia in children affected by autism spectrum disorder: The role of melatonin in treatment.
Effective treatment for insomnia
We explored the effectiveness of melatonin in treating insomnia in children with autism spectrum disorder (ASD). The article reviewed current research and guidelines, emphasizing melatonin's safety and efficacy in this context.
Melatonin, particularly in prolonged-release formulations, shows promise as a long-term solution when traditional behavioral treatments fall short. This treatment option is approved for children aged 2 to 18 with ASD, providing relief from insomnia that affects both young patients and their caregivers.
While the current findings are encouraging, the authors acknowledged that more research is necessary to refine these approaches.
Melatonin, particularly in prolonged-release formulations, shows promise as a long-term solution when traditional behavioral treatments fall short. This treatment option is approved for children aged 2 to 18 with ASD, providing relief from insomnia that affects both young patients and their caregivers.
While the current findings are encouraging, the authors acknowledged that more research is necessary to refine these approaches.
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Most Useful Reviews
8.3
Positive results with melatonin
These are working for me so far. I had previously tried another melatonin brand without success. A friend recommended these, and they've helped me fall asleep within 15 minutes every night. I'm very happy with them as I struggle with insomnia, and I haven’t experienced any side effects.
Read More
8
Eased my insomnia
But I truly enjoy these gummies. Initially, I bought them for my kids as they struggle to fall asleep, often staying awake until 2am. However, I find myself using them more frequently due to my severe insomnia, which can leave me awake for 4-5 days straight. These gummies definitely aid my sleep. I've tried many forms of melatonin, but these have a pleasant taste (keep them out of children's reach!). I can take two and within 30 minutes, I'm relaxed and drifting off. While they don't completely knock me out, I still wake during the night to tend to my children if necessary. They've markedly improved my sleep quality, leaving me less fatigued throughout the day.
Read More
10
Improved my sleep
Greatly improved my sleep! I have struggled with insomnia for nearly six years. About 10 months ago, I decided to try these, and it has been one of my greatest decisions ever. My main issues were getting to sleep and staying asleep. Now, I take one gummy each night (two if I need to wake up earlier) and about 85% of the time, I sleep through the night. If I do wake, it's only 1-2 times compared to the usual 7-8 times without melatonin. These gummies have significantly improved my overall sleep and have even regulated my sleep cycle. I've tried another brand in pill form, but these work much faster. I'm on my second bottle and will likely continue purchasing after I run out.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.8
- All Researches
9
Melatonin delivery enhances sleep
Silk fibroin microneedles loaded with melatonin for circadian rhythm regulation.
Direct impact on insomnia treatment.
We developed a new way to deliver melatonin for those struggling with insomnia by creating microneedles made from silk fibroin. These tiny needles are designed to improve how the body absorbs melatonin, making it easier for people to get to sleep and stay asleep.
Our research shows that these microneedles can release melatonin steadily over a period of 11 hours. When we tested it on animals, we found that the microneedles maintained stable levels of drug in the bloodstream for up to 8 hours. This is promising news for individuals who may need help with their sleep cycles.
Additionally, the microneedles not only helped regulate sleep but also made a noticeable difference in anxiety levels in insomnia model rats. By improving the disrupted circadian rhythms, melatonin loaded into these microneedles could lead to significant therapeutic benefits.
We believe this innovative approach could enhance patient compliance and provide effective sleep aid for many in need. It’s an exciting development in the field of transdermal drug delivery for improving sleep quality and overcoming insomnia.
Our research shows that these microneedles can release melatonin steadily over a period of 11 hours. When we tested it on animals, we found that the microneedles maintained stable levels of drug in the bloodstream for up to 8 hours. This is promising news for individuals who may need help with their sleep cycles.
Additionally, the microneedles not only helped regulate sleep but also made a noticeable difference in anxiety levels in insomnia model rats. By improving the disrupted circadian rhythms, melatonin loaded into these microneedles could lead to significant therapeutic benefits.
We believe this innovative approach could enhance patient compliance and provide effective sleep aid for many in need. It’s an exciting development in the field of transdermal drug delivery for improving sleep quality and overcoming insomnia.
Read More
9
Melatonin's Potential in Insomnia Treatment
Highly relevant study findings
We aimed to understand the impact of melatonin on insomnia, focusing on its ability to improve sleep quality. The study methodically assessed the isolated effects of melatonin without interference from other treatments. This design allowed us to clearly see how melatonin worked on its own.
Throughout the study, we observed that melatonin could effectively decrease the time it takes to fall asleep and enhance overall sleep duration. Participants reported improvements in their sleep patterns, suggesting that melatonin has a beneficial effect for those struggling with insomnia.
Overall, our exploration into melatonin's influence on insomnia highlights it as a relevant sleep aid. For anyone seeking a natural solution to restless nights, melatonin may indeed offer a promising option.
Throughout the study, we observed that melatonin could effectively decrease the time it takes to fall asleep and enhance overall sleep duration. Participants reported improvements in their sleep patterns, suggesting that melatonin has a beneficial effect for those struggling with insomnia.
Overall, our exploration into melatonin's influence on insomnia highlights it as a relevant sleep aid. For anyone seeking a natural solution to restless nights, melatonin may indeed offer a promising option.
Read More
9
Melatonin enhances sleep and heart health
Unlocking the Heart's Guardian: Exploring Melatonin's Impact on the Cardiovascular System.
Highly relevant to insomnia treatment
We observed how melatonin, often linked to better sleep, shows promising potential beyond just treating insomnia. Recent studies spotlight its effectiveness in promoting restful sleep with minimal side effects, making it a popular choice for people struggling with sleep issues.
Over time, we’ve noticed an uptick in melatonin use in the United States, shifting from 0.08% in 2005-2006 to about 0.28% in 2017-2018. This increase corresponds with growing recognition of melatonin's role in not just managing sleep disorders, but also in supporting muscle recovery and enhancing physical performance.
We also found that individuals with various cardiovascular conditions often have lower melatonin levels, which may contribute to higher risks of heart-related incidents. This connection suggests melatonin may have protective effects on heart health, in addition to its sleep benefits.
Overall, our exploration leads us to conclude that melatonin serves as both a sleep aid and a possible guardian for cardiovascular health, encouraging further research into its multiple benefits.
Over time, we’ve noticed an uptick in melatonin use in the United States, shifting from 0.08% in 2005-2006 to about 0.28% in 2017-2018. This increase corresponds with growing recognition of melatonin's role in not just managing sleep disorders, but also in supporting muscle recovery and enhancing physical performance.
We also found that individuals with various cardiovascular conditions often have lower melatonin levels, which may contribute to higher risks of heart-related incidents. This connection suggests melatonin may have protective effects on heart health, in addition to its sleep benefits.
Overall, our exploration leads us to conclude that melatonin serves as both a sleep aid and a possible guardian for cardiovascular health, encouraging further research into its multiple benefits.
Read More
9
Ramelteon as insomnia treatment
Treatment of Depression-Related Circadian Rhythm Sleep-Wake Disorder (CRSWD) With Melatonin Receptor Agonist Ramelteon: A Case Report.
High relevance to insomnia treatment
We explored how the melatonin receptor agonist ramelteon could help a high school student struggling with delayed sleep-wake phase disorder (DSWPD) coupled with depression. This particular condition is a type of insomnia where the body’s internal clock is out of sync with the external world, often leading to significant challenges in daily life.
The treatment showcased positive outcomes, as the patient experienced improved sleep patterns after using ramelteon. These improvements enabled the student to re-engage with school, achieve university goals, and eventually secure employment after graduation. This case suggests that melatonin could be a valuable option for addressing insomnia, especially in individuals also facing depressive symptoms.
Overall, our observations point to the potential of ramelteon as a promising treatment for those experiencing circadian rhythm sleep disorders alongside depression, emphasizing the need for further clinical exploration in this area.
The treatment showcased positive outcomes, as the patient experienced improved sleep patterns after using ramelteon. These improvements enabled the student to re-engage with school, achieve university goals, and eventually secure employment after graduation. This case suggests that melatonin could be a valuable option for addressing insomnia, especially in individuals also facing depressive symptoms.
Overall, our observations point to the potential of ramelteon as a promising treatment for those experiencing circadian rhythm sleep disorders alongside depression, emphasizing the need for further clinical exploration in this area.
Read More
9
Melatonin shows promise for insomnia
Temazepam or Melatonin Versus Placebo for the Treatment of Insomnia in Advanced Cancer: A Three-Arm, Double-Blind, Phase III, Multicenter, Randomized Clinical Trial.
Study directly evaluates melatonin's effects.
We conducted a multicenter trial to explore how melatonin and temazepam affect insomnia in patients with advanced cancer. In our study, we compared these treatments to a placebo among individuals reporting an insomnia severity index (ISI) score above 11.
A total of 21 participants were randomly assigned to receive either temazepam, melatonin, or a placebo. We found that both temazepam and melatonin offered significant improvements in sleep quality compared to the placebo group, with the adjusted mean difference in ISI scores indicating a meaningful reduction in insomnia symptoms.
It’s important to note, however, that neither treatment led to improvements in the overall quality of life. Participants tolerated both melatonin and temazepam well, which is a positive indication for their use in managing sleep disturbances among cancer patients. These findings suggest that melatonin can have a beneficial effect on insomnia in this population, but further studies with larger groups are needed to confirm these results.
A total of 21 participants were randomly assigned to receive either temazepam, melatonin, or a placebo. We found that both temazepam and melatonin offered significant improvements in sleep quality compared to the placebo group, with the adjusted mean difference in ISI scores indicating a meaningful reduction in insomnia symptoms.
It’s important to note, however, that neither treatment led to improvements in the overall quality of life. Participants tolerated both melatonin and temazepam well, which is a positive indication for their use in managing sleep disturbances among cancer patients. These findings suggest that melatonin can have a beneficial effect on insomnia in this population, but further studies with larger groups are needed to confirm these results.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
8.3
Positive results with melatonin
These are working for me so far. I had previously tried another melatonin brand without success. A friend recommended these, and they've helped me fall asleep within 15 minutes every night. I'm very happy with them as I struggle with insomnia, and I haven’t experienced any side effects.
Read More
8
Eased my insomnia
But I truly enjoy these gummies. Initially, I bought them for my kids as they struggle to fall asleep, often staying awake until 2am. However, I find myself using them more frequently due to my severe insomnia, which can leave me awake for 4-5 days straight. These gummies definitely aid my sleep. I've tried many forms of melatonin, but these have a pleasant taste (keep them out of children's reach!). I can take two and within 30 minutes, I'm relaxed and drifting off. While they don't completely knock me out, I still wake during the night to tend to my children if necessary. They've markedly improved my sleep quality, leaving me less fatigued throughout the day.
Read More
10
Improved my sleep
Greatly improved my sleep! I have struggled with insomnia for nearly six years. About 10 months ago, I decided to try these, and it has been one of my greatest decisions ever. My main issues were getting to sleep and staying asleep. Now, I take one gummy each night (two if I need to wake up earlier) and about 85% of the time, I sleep through the night. If I do wake, it's only 1-2 times compared to the usual 7-8 times without melatonin. These gummies have significantly improved my overall sleep and have even regulated my sleep cycle. I've tried another brand in pill form, but these work much faster. I'm on my second bottle and will likely continue purchasing after I run out.
Read More
6.8
Better sleep quality
Review from a chronic insomniac. In my early 30s, I've suffered from insomnia for as long as I remember. I fall asleep easily but wake after 2-4 hours and am awake for hours. After becoming fed up, I tried melatonin gummies, as I dislike pills. They helped me fall asleep quickly; however, I still awaken but can now return to sleep within 30 minutes instead of hours, which I am very pleased about. They taste great too, like candy! Some claim the bottle is misleading, but it clearly states that one serving is 5mg, with two gummies equalling one serving.
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7.5
Helps with wakefulness
Helps me fall back to sleep after waking. I've struggled with insomnia for years, primarily with returning to sleep after waking. This melatonin really assists with that. I take two chews before bed and another before turning off the lights, significantly improving my sleep quality. They taste good, though can be a bit dried out when ordered from Amazon.
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Frequently Asked Questions
No FAQs are available for this product and symptom.
