NOW Supplements Inulin Prebiotic Powder

Inulin improves cardiovascular health

Based on 10 Researches

Zhang K, Zeng Y, Li J, Huang Y, Zhang N, et al. Inulin alleviates atherosclerosis through improving lipid metabolism, inflammation, and gut microbiota in ApoE-knockout mice: the short-chain is more efficacious. Front Pharmacol. 2024;15:1445528. doi:10.3389/fphar.2024.1445528

We investigated how inulin, a type of fiber, affects atherosclerosis, a condition that can lead to serious heart and brain problems. Using ApoE-knockout mice fed a high-fat diet, we tested the effects of two forms of inulin: short-chain and long-chain. By administering these types of inulin for 12 weeks, we aimed to understand their impact on lipid metabolism, inflammation, and gut health.

Our findings revealed that inulin can help protect against atherosclerosis. Specifically, short-chain inulin proved to be more effective than its long-chain counterpart. We saw improvements in lipid metabolism, reduced inflammation, and healthier gut microbiota. This suggests that when it comes to using inulin as a dietary intervention for heart health, short-chain inulin stands out as the more promising option.

Overall, this study highlights the potential of inulin to play a role in managing cardiovascular health, with implications for dietary recommendations. It’s exciting to consider how incorporating this fiber into our diets might support cardiovascular well-being.

Positive results noted

Most Useful Review

8 people found this helpful

Excellent! This is a remarkable supplement for a child with autism. We administer inulin as per the Nemechek protocol and have observed positive results. It effectively regulates intestinal function – easing constipation and strengthening diarrhoea, depending on the dosage. The taste is sweet, and it dissolves well in both drinks and food.

Cold details

Convenient immune support

2 people found this helpful

I trust this brand's supplements completely! I've tried various products and found them to be of excellent quality at a reasonable price. I bought this for immune support during colds, and it has performed excellently. The packaging is tidy, closing securely with capsules that are easy to use.

Colitis details

Calmer stomach symptoms

This product has significantly improved my Colitis symptoms, including diarrhoea, bloating, and gas. My stomach feels noticeably calmer now. It’s also much cheaper than sodium butyrate supplements, working similarly. However, I recommend researching possible liver harm before purchasing.

Depression details

Inulin reduces depression in migraines

Vajdi M, Khorvash F, Askari G. A randomized, double-blind, placebo-controlled parallel trial to test the effect of inulin supplementation on migraine headache characteristics, quality of life and mental health symptoms in women with migraine. Food Funct. 2024;15:10088. doi:10.1039/d4fo02796e

We conducted a randomized double-blind placebo-controlled trial to understand how inulin supplementation influences depression in women prone to migraines. A total of 80 participants, aged between 20 to 50 years, were given either 10 grams of inulin or a placebo daily for 12 weeks.

Throughout the study, we monitored changes in depression, anxiety, stress, and the overall quality of life. Remarkably, we observed significant improvements in mental health for those taking inulin, particularly notable reductions in depression scores. Specifically, participants in the inulin group experienced a drop of about 4.47 points in their depression scores, which was statistically significant.

While the focus of the study was primarily on migraine symptoms, these mental health improvements suggest that inulin could play a supportive role in enhancing emotional well-being for those suffering from migraines. However, it's important to note that we did not see any substantial changes in quality of life scores between the two groups. Overall, our findings advocate for the potential benefits of inulin supplementation on mental health in women facing chronic migraines.

7.5

Improved emotional balance

Most Useful Review

1 people found this helpful

We read an article discussing the benefits of inulin, highlighting the connection between the brain and intestines. A balanced gut, with the right ratio of probiotics and prebiotics, is directly linked to emotional wellbeing, including stress, depression, and overall immunity. We administered inulin to a child alongside probiotics, and it genuinely works. The flavour is pleasant, and the product is long-lasting. Inulin also aids in reducing fat in the liver and muscles, lowers bad cholesterol, and diminishes overall body fat, making it a popular choice for healthy weight loss. A splendid product!

Eczema details

Eczema relief observed

I take it for blood sugar control and to improve my intestinal environment. It seems effective for me. When my blood sugar rises above the norm, eczema appears on my neck. However, upon taking inulin 15 minutes before meals, the eczema disappeared. I was careful not to eat high-carbohydrate foods. My bowel movements have become smoother, and I lost 1 kilogram in a week without any changes to my routine.

Flu details

This is my second order. I believe this prebiotic powder has helped with my reflux, and I am no longer taking reflux medication.

Autism details

35 people found this helpful

My child faces autism, and I decided to try the Nemechek protocol with this inulin. The success has been astounding! For two years, we have been using it daily, and it has significantly cleared his system. We're grateful for this high-quality product!

Brain Tumor details

Bradykinin enhances tumor permeability

Inamura T, Black KL. Bradykinin selectively opens blood-tumor barrier in experimental brain tumors. J Cereb Blood Flow Metab. 1994;14:862.

We investigated the effects of bradykinin on the permeability of tumor capillaries to various substances, including inulin, in a model of RG2 glioma in rats. In this study, bradykinin was administered through the carotid artery to see how it would alter the capillary barrier in brain tumors.

Our findings revealed that bradykinin significantly increased the permeability of tumor vessels to several tracers, including inulin. Specifically, the permeability for inulin was 23.92, compared to just 6.20 in the control group receiving saline. This indicates that bradykinin may play a role in enhancing the ability of substances like inulin to penetrate brain tumors, which could have implications for drug delivery in such conditions.

It's important to note that the permeability changes observed were limited to the tumor sites and did not affect normal brain tissue. Moreover, once the bradykinin infusion was stopped, the increased permeability returned to baseline levels within 20 minutes, emphasizing the temporary nature of its effect. Overall, our research highlights the potential for using bradykinin to improve the delivery of treatments for brain tumors by temporarily opening up the blood-tumor barrier.

7.5

Gut-brain connection

Most Useful Review

7 people found this helpful

Inulin works wonderfully! We’ve given up probiotics to focus solely on prebiotics, and it has profoundly impacted my life and my children’s. It’s crucial to nourish the existing good bacteria rather than continuously introducing new strains. I've seen improvements in my daughter's concentration and a decrease in her aggressiveness. A healthy gut promotes a healthy brain—this prebiotic is a fantastic choice!

Liver Disease details

Yang Z, Su H, Lv Y, Tao H, Jiang Y, et al. Inulin intervention attenuates hepatic steatosis in rats via modulating gut microbiota and maintaining intestinal barrier function. Food Res Int. 2023;163:112309. doi:10.1016/j.foodres.2022.112309

Inulin improves liver health

We explored how inulin, a prebiotic, can positively influence liver health, particularly in cases of nonalcoholic fatty liver disease (NAFLD). The study involved rats fed a high-sucrose diet, revealing that those receiving inulin showed less liver fat buildup and inflammation compared to a control group. It appeared that inulin helped restore key liver and fat metabolism markers, which play vital roles in managing fat accumulation in the liver.

Moreover, we observed that inulin supplementation improved the gut barrier function. By increasing the levels of certain proteins that help keep our gut intact, inulin seems to help prevent harmful substances from entering the body. This represents a significant advance in understanding not just the direct impact of inulin, but how gut health interconnects with liver conditions.

Our analyses of gut bacteria also yielded encouraging results. Inulin intake led to a rise in beneficial bacteria linked to short-chain fatty acid production, while harmful bacteria were decreased. This shift suggests that inulin may help create a more balanced gut environment, which is crucial for maintaining overall health. In addition to these findings, we noted changes in tryptophan metabolism that may further explain the benefits of inulin. Overall, we feel that inulin holds promise as a dietary intervention for preventing and managing NAFLD in the future.

7.5

Enhances immunity

Most Useful Review

1 people found this helpful

I purchased Inulin for regular bowel movements, and it's a good prebiotic with several noted benefits. The powder is pleasant to drink, with a sweet taste. It may increase immunity, cleanse liver cells, and enhance digestion, allowing better absorption of vitamins and minerals. I recommend it.

Reflux details

It has resolved my issue of reflux and trapped gases, and I find it helpful overall.

Candidiasis details

Highly effective treatment

47 people found this helpful

This is the only product that has ever effectively treated my Candidiasis. I take one teaspoon three times daily, in the middle of meals, with 10-12 ounces of water. Taking it outside mealtimes or without enough water can lead to intestinal discomfort, which I experienced. Give it a month to see its full effect.

Cold Sores details

3 people found this helpful

I use it every day, and it has been very effective for me. One or two teaspoons mixed with drinks and soups, once or twice daily, works well. It's a fine white powder, similar to powdered sugar, and best mixed with warm liquids since it hardens in cold ones. I enjoy it with my morning hot water or tea and sometimes in protein shakes. About an hour after drinking, my stomach starts to feel active. I used to be constipated, only going a few times a week, but now it works consistently. This product is lovely as it helps without causing stomach aches.

Gastritis details

Austarheim I, Nergard CS, Sanogo R, Diallo D, Paulsen BS. Inulin-rich fractions from Vernonia kotschyana roots have anti-ulcer activity. J Ethnopharmacol. 2012;144:82. doi:10.1016/j.jep.2012.08.031

Likely Very Effective

Inulin aids ulcer prevention

We examined the potential effects of inulin-rich extracts from the roots of Vernonia kotschyana on gastritis, particularly its anti-ulcer properties. The roots are recognized in Mali for their traditional use in treating gastric issues like gastritis and ulcers, sold under the name Gastrosedal.

In our research, we analyzed two different water extracts from these roots, from 50°C and 100°C extractions, to see how they could impact stomach ulcers induced in mice. The study highlighted that both extracts contained high levels of inulin—98% in the cooler extract and 83% in the hotter one.

The results were promising, as both VK50-I and VK100-I displayed a significant ability to inhibit ulcer formation in the mice. Interestingly, despite these positive findings, we did not observe any significant immunomodulating activities or toxicity associated with the extracts.

This suggests that inulin may play a vital role in safeguarding the gastrointestinal tract's health, particularly in combating conditions such as gastritis. Overall, our findings support the traditional use of Vernonia kotschyana as a natural remedy for stomach-related ailments.

No stomach problems

Most Useful Review

11 people found this helpful

The best prebiotic; it tastes like cotton candy, maybe even better! It has been a great help for me with gastritis. Three teaspoons a day, and I experience no stomach problems.

Gastroenteritis details

Questionable

Huang W, Deng Z, Lu L, Ouyang Y, Zhong S, et al. Polysaccharides from soybean residue fermented by alleviate DSS-induced gut barrier damage and microbiota disturbance in mice. Food Funct. 2022;13:5739. doi:10.1039/d2fo00137c

Inulin's role in gastroenteritis

In our exploration of how inulin might help with gastroenteritis, we examined its effects using a well-designed study that included mice experiencing symptoms induced by dextran sulfate sodium (DSS). During the study, these mice were divided into groups and treated with either inulin or a different polysaccharide extracted from fermented soybean residue, allowing for comparative analysis.

We observed that inulin acted as a positive control, showing potential benefits similar to the compounds being tested from soybean residue. However, since the effects of inulin were evaluated concurrently with another polysaccharide, it’s challenging to completely disentangle its specific contributions to improvements in symptoms like weight loss and gut barrier integrity.

Notably, the findings indicated that inulin, along with other treatments, helped to enhance gut barrier function and lower inflammation indicators in the mice. This suggests that while inulin holds promise, the precise extent of its individual effects on gastroenteritis need further investigation to make definitive claims.

Improved appetite noted

Most Useful Review

My daughter faced gut issues after a bout of gastroenteritis. Despite trying digestive enzymes and many probiotics, none were successful. However, this solution effectively reduced her bloating and enhanced her appetite. It also tastes lovely.

Hypothyroidism details

Supports bowel recovery

102 people found this helpful

Very good for supporting bowel function and recovery from hypothyroidism. It has a slightly sweet, marshmallow-like flavour and can be taken directly by mouth with a little water, giving it a lollipop effect as it doesn't dissolve well and remains in the package when mixed with water.

Obesity details

Reimer RA, Theis S, Zanzer YC. The effects of chicory inulin-type fructans supplementation on weight management outcomes: systematic review, meta-analysis, and meta-regression of randomized controlled trials. Am J Clin Nutr. 2024;120:1245. doi:10.1016/j.ajcnut.2024.09.019

Chicory ITFs aid weight management

We examined how inulin-type fructans (ITFs) from chicory can help manage weight. In a thorough systematic review that considered studies up until early 2023, we identified 32 trials that looked at the effects of chicory ITF supplementation on various weight-related outcomes.

The results were promising. Participants taking chicory ITFs experienced a significant reduction in body weight, with an average loss of about 0.97 kg compared to those receiving a placebo. We also noted decreases in body mass index (BMI), fat mass, and waist circumference. For those who continued the supplementation for more than eight weeks, there was an additional reduction in body fat percentage.

Interestingly, we did not find that the type of ITF or the dosage significantly affected these outcomes. Moreover, these benefits appeared consistent regardless of participants' health status. However, we should mention that there was notable variability in the results for body weight and body fat percentage, which suggests some differences in individual responses to the treatment.

Effective pairing

Most Useful Review

Excellent! Combining inulin with probiotics proves very effective for visceral obesity.

Yeast Infection details

Probiotics and prebiotics against yeast

Chantanawilas P, Pahumunto N, Thananimit S, Teanpaisan R. Anticandidal Activity of Various Probiotic Lactobacillus Strains and Their Efficacy Enhanced by Prebiotic Supplementation. Curr Microbiol. 2024;81:271. doi:10.1007/s00284-024-03800-y

We explored the anticandidal potential of several probiotic Lactobacillus strains in combating yeast infections, particularly focusing on the role of inulin and some fruits as prebiotics. Our study assessed how these prebiotics influenced the growth and effectiveness of the probiotic strains against Candida, a common yeast responsible for infections.

We found that the anticandidal activity varied among the different Lactobacillus strains, with non-adjusted cell-free supernatants (CFSs) being the most effective. Notably, strains like Lacticaseibacillus rhamnosus SD11 showed strong results against yeast, especially when combined with 2% mangosteen as a prebiotic. This combination not only promoted the growth of beneficial probiotic bacteria but also enhanced the production of short-chain fatty acids and antioxidants, which are vital for fighting off yeast.

However, while the study highlights the positive effects of probiotics and the benefits of prebiotics like mangosteen, it does not isolate inulin's specific impact on yeast infection. Therefore, while we observed a boost in anticandidal activity with prebiotic supplementation, particularly mangosteen, we cannot definitively conclude inulin's individual effectiveness without further focused research.

Skin infection rescue

Most Useful Review

49 people found this helpful

Helped worked wonders for my dog! My three-year-old female pit bull has suffered from severe allergies and yeast/bacterial infections of the skin for nearly two years. I had to give her multiple doses of Benadryl daily just to manage the itch. I tried various treatments that only provided temporary relief. After researching probiotics, I added some Inulin powder with a plant enzyme probiotic to her diet. This has been a lifesaver. She no longer chews, licks, or scratches excessively. A quality product that delivered the results I wanted. Will buy again!

Bone Pain details

Immune and bone support

Inulin is primarily purchased for intestinal health, but in our family, we observed its significant impact on immune system strengthening and my mother's bone pain has also ceased since she started taking it.

Cancer details

Inulin's effects on colonic fibrosis

Based on 14 Researches

Ji K, Zhang M, Du L, Wang J, Liu Y, et al. Exploring the Role of Inulin in Targeting the Gut Microbiota: An Innovative Strategy for Alleviating Colonic Fibrosis Induced By Irradiation. J Agric Food Chem. 2024;72:5710. doi:10.1021/acs.jafc.3c03432

We explored the effects of inulin supplements on colonic fibrosis caused by radiation therapy for treating pelvic and abdominal cancers. Chronic radiation enteropathy often leads to difficult gastrointestinal issues, and understanding how inulin can help is crucial.

In our study, we found that inulin seems to promote the growth of beneficial bacteria in the gut, which in turn boosts the production of short-chain fatty acids (SCFAs). By conducting experiments on mice with chronic radiation enteropathy, we discovered that when we transplanted gut microbiota and their metabolites from inulin-treated mice, the levels of colonic fibrosis significantly decreased.

Additionally, administering these metabolites led to a drop in the expression of genes related to fibrosis and collagen production in mouse embryonic fibroblast cells. It appears that these inulin-derived metabolites also inhibit the pathways involved in the production of the extracellular matrix. Overall, our findings highlight the promise of inulin as a novel approach to help mitigate chronic radiation-induced colonic fibrosis.

7.5

Boosts immune system

Most Useful Review

6 people found this helpful

I chose Inulin over other prebiotics after consulting with my gastroenterologist. It reaches the bowels where beneficial bacteria grow and inhibits certain fats' growth. Inulin serves as a valuable dietary fibre and helps reduce the risk of cancer while enhancing immune functions. If this review has helped you, please give it a thumbs up. Thank you!

Cholecystitis details

Effective gallbladder support

I highly recommend taking inulin as it significantly aids lazy bowels and is beneficial for gallbladder stasis and high sugar levels. In today's diet, where refined products dominate, we often lack fibre. NOW Foods produces quality supplements at reasonable prices, and I found this product particularly effective. My constipation has vanished, my intestines are functioning well, and my gastrointestinal issues have improved. Additionally, the taste is enjoyable.

Insomnia details

Constipation alleviated

Improve constipation and insomnia. This product has significantly enhanced my sleep quality.

Common Cold details

Effective for constipation

37 people found this helpful

I thought that oligosaccharides might help adjust the intestinal environment of my eldest daughter, who has suffered from constipation. I incorporated inulin, which acts as an oligosaccharide, into her diet, placing it in her food as it’s slightly sweet. The Now Foods inulin offers good value for money, though it dissolves poorly in cold items. Thankfully, my daughter's constipation has improved, and the unpleasant smell post-defecation has been reduced, indicating its effectiveness.

Diabetes details

1 people found this helpful

To prevent diabetes, I take inulin before meals as it moderates sugar absorption, aiding in maintaining stable levels.

Leg Cramps details

Works brilliantly! Inulin is excellent for your "internal plumbing". I've used it for years without any side effects. There’s no cramping and no urgent trips to the bathroom. It works gently and consistently. A good product.

Sleep Apnea details

Dramatic sleep improvement

4 people found this helpful

We’re on the second bottle and after just a week noticed a dramatic improvement in sleep quality. After watching a documentary by Dr Moseley, who tested gut health, prebiotic fibre, and sleep, we decided to try Inulin before bed, and yes, it works. Also helps with dream recall and those early morning wake-ups.

Ulcer details

Inulin alleviates ulcerative colitis

Based on 10 Researches

Zhou J, Wang J, Li D, Zhang Z, Wang C, et al. An inulin-type fructan CP-A from alleviates TNBS-induced ulcerative colitis based on serum-untargeted metabolomics. Am J Physiol Gastrointest Liver Physiol. 2024;326:G216. doi:10.1152/ajpgi.00214.2023

We investigated how inulin-type fructan CP-A, a key component found in certain polysaccharides, influences ulcerative colitis (UC), an inflammatory disease marked by symptoms like abdominal pain, diarrhea, and bloody stools. To conduct this research, we used a rat model treated with 2,4,6-trinitrobenzene sulfonic acid (TNBS) to simulate UC and an in vitro model with colonic epithelial cells exposed to lipopolysaccharides (LPS) to better understand the cellular response.

Through our experiments, we discovered that CP-A significantly lessens colonic injuries and reduces markers associated with inflammation, such as interleukin-8 and tumor necrosis factor-alpha. Furthermore, we observed improvements in levels of protective substances like interleukin-10 and transforming growth factor-beta after treatment with CP-A. In our in vitro tests, CP-A effectively lowered nitric oxide and interleukin-1 beta production following LPS stimulation, indicating a reduction in inflammatory responses.

Our metabolic analysis revealed a connection between CP-A therapy and the mammalian target of rapamycin (mTOR) signaling pathway. Both in vivo and in vitro validations suggested that this pathway plays a critical role in CP-A's ability to alleviate UC by inhibiting inflammation-related signaling mechanisms. These findings can pave the way for new treatment approaches for patients suffering from ulcerative colitis, suggesting that inulin-type fructan CP-A holds therapeutic promise in managing and potentially improving this challenging condition.

7.5

Supports gut health

Most Useful Review

4 people found this helpful

Inulin is essential for everyone! It consists of fructose molecules and is often prescribed by doctors to moderately lower blood sugar levels. However, it also serves another important role. After taking antibiotics and experiencing intestinal issues, I needed to restore my health. Leaky gut syndrome hinders food absorption and weakens immunity, prompting my search for methods to improve microflora. Instead of relying on bacteria capsules, which contain foreign pig intestinal bacteria, I prefer to cultivate beneficial bacteria in my own intestines. Inulin, a prebiotic, supports this growth. By consuming it regularly, I can foster my own beneficial bacteria, which convert inulin into short-chain fatty acids that nourish colon cells and heal the intestinal lining, relieving ulcers and other issues. I use one teaspoon dissolved in water at night, combined with an Acidophilus capsule for faster results.

Urinary Tract Infection details

Kuzmin IV, Slesarevskaya MN, Al-Shukri SH. [Antiadhesive strategy for non-antibacterial prophylaxis of recurrent lower urinary tract infections]. Urologiia. 2021.

Inulin's role in UTI prevention

We investigated the effectiveness of a biological additive, Ecocystin, which includes inulin and D-mannose, aimed at preventing recurrent lower urinary tract infections (LUTI) in women. The study included 74 women aged between 21 and 75 years, all of whom had experienced recurrent LUTIs. After initial treatment, participants were divided into two groups. The main group received Ecocystin, while the control group did not receive any supplementation.

Over the course of the study, we monitored clinical indicators and gathered results at various intervals: on the third day, and again after three and six months. Notably, the inclusion of D-mannose in Ecocystin was highlighted for its antiadhesive properties, which can help prevent bacteria from sticking to urinary tract walls. While inulin was part of the formulation as a prebiotic, the isolation of its effects in the context of this study is challenging given its combination with D-mannose.

Our findings indicated that Ecocystin was effective in reducing the recurrence of LUTIs, presenting it as a viable alternative to traditional antibiotic treatments. Given the rising concerns over antibiotic resistance, remedies that employ mechanisms like those provided by D-mannose are increasingly important in urinary health.

7.5

Restores microflora

Most Useful Review

1 people found this helpful

The gastrointestinal tract says "THANKS"! The primary action of inulin is its probiotic capacity; it restores microflora positively affecting my digestive tract. This promotes proper metabolism and a feeling of lightness in the morning. I highly recommend it to everyone who values their well-being.

Anxiety details

Inulin reduces anxiety in migraines

Based on 10 Researches

We conducted a fascinating study to understand how inulin supplementation might affect anxiety levels in women suffering from migraines. By design, this was a randomized, double-blind, placebo-controlled trial involving 80 women aged 20 to 50 years old. Participants received either 10 grams of inulin daily or a placebo for 12 weeks.

Our results showed promising findings regarding anxiety. Specifically, we observed a significant decrease in anxiety levels among those taking inulin, with a reduction of 4.37 points compared to the placebo group. This indicates that inulin may play a role in enhancing mental well-being in those experiencing migraine headaches.

It's worth noting that while we found improvements in anxiety and other mental health symptoms such as stress and depression, the quality of life scores did not show a significant difference between the two groups. This could suggest that while inulin helps with anxiety, it might not immediately influence overall quality of life in women with migraines.

Such findings are encouraging and suggest that inulin supplementation can provide a natural avenue to alleviate some mental health challenges associated with migraine episodes. We believe further research could shed more light on these effects.

Brain clarity regained

Most Useful Review

9 people found this helpful

There is a noticeable result! I had colon issues and began taking a teaspoon of inulin each day with green tea, which was delightful—like childhood toffee. I soon increased it to two teaspoons, and the entire jar was gone within weeks. The effects were almost immediate: my stool improved, and bloating and flatulence vanished. As a bonus, my mental clarity improved, and my anxiety diminished. My mood has brightened significantly! I will certainly purchase more.

Autoimmune Disorder details

Inulin protects against type 1 diabetes

Based on 12 Researches

Guimarães JB, Rodrigues VF, Pereira ÍS, Manso GMDC, Elias-Oliveira J, et al. Inulin prebiotic ameliorates type 1 diabetes dictating regulatory T cell homing via CCR4 to pancreatic islets and butyrogenic gut microbiota in murine model. J Leukoc Biol. 2024;115:483. doi:10.1093/jleuko/qiad132

We explored how inulin, a type of prebiotic fiber, impacts the immune response in the context of type 1 diabetes (T1D) using a specific mouse model. Our findings showed that mice treated with inulin alongside a chemical that induces diabetes, called streptozotocin, did not develop the disease. In fact, these mice had lower blood glucose levels, reduced inflammation in their pancreas, and more balanced insulin levels compared to those not receiving inulin.

The mice that received inulin also demonstrated an interesting change in their gut health, showcasing an increase in beneficial bacteria like Bifidobacterium and Akkermansia muciniphila, as well as higher levels of butyrate, a short-chain fatty acid crucial for gut health. This improved gut microbiota seemed to support regulatory T cells, which play an important role in immune regulation.

Specifically, we noted that inulin helped recruit these regulatory T cells into the pancreas, a site critical for managing the immune response in diabetes. This recruitment depended on a specific pathway involving something known as CCR4. When we looked at mice lacking this CCR4 receptor, the beneficial effects of inulin were significantly reduced, highlighting its importance.

Overall, these findings suggest that inulin could be a promising nutritional strategy for enhancing immune health and potentially protecting against autoimmune conditions like T1D.

Effective for constipation

Most Useful Review

117 people found this helpful

I ordered this for my mother, age 76, multiple times. The benefits have been immense! At her age, constipation can be an issue, so finding a safe, regular remedy is essential. This fibre works wonders—she now has a daily bowel movement, and her gastrointestinal tract thanks the manufacturer for this remarkable and affordable product. One teaspoon daily is all she needs. The taste is slightly sweet, and we combine it with Paradise Herbs Zelenka for even better results. I will definitely order again.

Blood Clot details

More effective than probiotics

29 people found this helpful

I’ve taken probiotics but added inulin after dinner recently. I find that mornings now come with bowel movements more easily; inulin is significantly more effective than probiotics alone. My average fasting blood sugar dropped from 7 to 5.5 after just two days of inulin. As someone who injects insulin daily, this improvement is fantastic news for me.

Hypertension details

Inulin reduces pulmonary hypertension effects

Based on 6 Researches

USERS' SCORE

Good

Based on 3 Reviews

Pakhomov NV, Kostyunina DS, Macori G, Dillon E, Brady T, et al. High-Soluble-Fiber Diet Attenuates Hypoxia-Induced Vascular Remodeling and the Development of Hypoxic Pulmonary Hypertension. Hypertension. 2023;80:2372. doi:10.1161/HYPERTENSIONAHA.123.20914

We explored how a high-soluble-fiber diet, specifically one rich in inulin, impacts pulmonary hypertension in a controlled study involving mice. After feeding them diets with either 0% or 16.9% inulin, we exposed the mice to hypoxic conditions for 21 days, aiming to see if inulin could lessen the effects of pulmonary hypertension brought on by low oxygen levels.

Our findings showed that the mice on the high-soluble-fiber diet experienced lower right ventricular systolic pressure and reduced pulmonary vascular resistance compared to those on the low-fiber diet. Notably, this dietary change altered the gut microbiome, promoting bacteria that produce beneficial short-chain fatty acids and decreasing harmful bacteria associated with disease. We also observed a decrease in certain inflammatory immune cells in the lungs, which may contribute to the positive effects on vascular remodeling.

This study presents exciting evidence that a high-soluble-fiber diet, particularly one rich in inulin, may have the potential to mitigate the effects of pulmonary hypertension caused by hypoxia. These results suggest that dietary choices can play a significant role in managing vascular health and highlight the significance of nutrients like inulin in improving overall lung function.

7.5

Positive digestive effects

Most Useful Review

By optimising inulin in my diet, I have found it can help reduce the risk of developing arterial hypertension and other cardiovascular diseases. I also noticed inulin's beneficial effects on the digestive system, promoting the growth of healthy intestinal microflora and enhancing digestion.

Rash details

28 people found this helpful

Recommend for everyone! I use inulin as part of the Nemechek protocol for my son. He enjoys the sweetened water. The therapy has yielded excellent results: his stool improved, and he no longer complains of tummy pain; the rash and crusts on his body have disappeared. I take inulin with water every morning in a minimal dose and noticed I am less drawn to sweets, which has always been a struggle for me in managing my weight.

Atrial Septal Defect details

Improvement in digestion

591 people found this helpful

Works!!! A child with atrial septal defect had significant gastrointestinal issues. We started a protocol using INULIN, and after over a month, the terrible flatulence and constant burping have ceased. The stools are now regular with good consistency and colour. I'm very pleased with this inulin's effectiveness, especially as it’s also reasonably priced without quality compromise! I've started using it too and will continue to order this product. I highly recommend it!

Pelvic Pain details

44 people found this helpful

After four years of unsuccessful treatment for stomach pain and a course of antibiotics, I began using probiotics to restore my microflora with Inulin as food for beneficial bacteria. I take one teaspoon twice daily in green tea or chicory milk, and it has helped eliminate rumbling and bloating, providing a sense of comfort. I also incorporated Doctovit, which aids the healing of the gastrointestinal tract and supports enzyme production. If you find my review helpful, a like would be appreciated!

Bacterial Infection details

Healthy microflora restored

Combining a prebiotic and probiotic has significantly improved my gut health. After starting this regimen, I noticed a normal stool pattern, reduced skin rashes, and an uplifted mood. Initially, I experienced bloating, but this subsided after a few days. A month later, bacterial culture tests indicated a healthy intestinal microflora, but those with IBS should start cautiously with small amounts.

Chronic Cough details

I have tried numerous solutions to maintain regular bowel movements, but I have found soft and gentle inulin to be highly effective for over a year. It operates naturally and without chemicals. If you suffer from chronic and long-lasting constipation, I recommend giving it a try—I take it at night.

Constipation details

Inulin aids constipation and depression

Zou H, Gao H, Liu Y, Zhang Z, Zhao J, et al. Dietary inulin alleviated constipation induced depression and anxiety-like behaviors: Involvement of gut microbiota and microbial metabolite short-chain fatty acid. Int J Biol Macromol. 2024;259:129420. doi:10.1016/j.ijbiomac.2024.129420

We investigated how dietary inulin can help manage constipation, particularly its role in alleviating related symptoms of depression and anxiety. To do this, we used male CD-1 mice and induced constipation through a specific medication.

With inulin incorporated into a standard diet, we observed a notable improvement in constipated mice. They experienced an increase in both the weight and moisture content of their feces, indicating better bowel function.

Beyond physical improvements, we also found that inulin treatment helped reduce behaviors associated with depression and anxiety. This was linked to a decrease in neuro-inflammation and protection against cellular damage in the brain's synapses. Importantly, inulin also supported gut health by enhancing the gut barrier and altering gut microbiota for the better.

While the gut microbiome reshaping was promising, we observed that when we depleted the gut microbiota with antibiotics, the benefits of inulin on mood were significantly diminished. Furthermore, inulin treatment boosted the levels of beneficial short-chain fatty acids (SCFAs), which were also shown to help improve depressive behavior when administered separately.

In conclusion, dietary inulin presents a valuable nutritional strategy for preventing depression linked to constipation by influencing both the gut microbiome and its metabolites.

Effective for constipation

Most Useful Review

190 people found this helpful

Great intestinal support! I bought this inulin to use with a probiotic from CGN. I drink the probiotic at night and inulin when I remember. Inulin nourishes beneficial intestinal flora. Previously, I suffered from constipation, sometimes going 4-5 days without a visit to the toilet, relying solely on Dufalac. Now, after combining the probiotic and inulin, my intestines are more active in the morning. Even while taking iron, which is known to cause constipation, this combination has worked wonders!

Osteoporosis details

Inulin shows promise against osteoporosis

Based on 13 Researches

Zhang D, Zhang S, Jiang K, Li T, Yan C. Bioassay-guided isolation and evaluation of anti-osteoporotic polysaccharides from Morinda officinalis. J Ethnopharmacol. 2020;261:113113. doi:10.1016/j.jep.2020.113113

We investigated how inulin from Morinda officinalis can help with osteoporosis, particularly looking at its different polysaccharide fractions. Using a well-established ovariectomized rat model, we discovered that these polysaccharides, especially the fractions MO50 and MOW50-1, significantly protected against bone loss.

The study showed that when these polysaccharides were administered at a dosage of 400 mg/kg/day, rats experienced less bone deterioration and improved bone quality. Specifically, we noticed enhancements in the structure of trabecular bone, as well as lower levels of markers that indicate bone turnover.

Through careful bioactivity-guided isolation, we identified two specific inulin-type fructans, which were linked to the potential anti-osteoporotic benefits. Particularly, one of these fructans (MOW50-1) encouraged the differentiation of bone-forming cells, suggesting it could play a role in promoting bone health.

Overall, our findings emphasize the promising potential of inulin from Morinda officinalis as a natural option for helping with osteoporosis management and prevention.

7.5

Improves calcium absorption

Most Useful Review

In addition to its prebiotic effects, inulin significantly increases calcium absorption, reducing osteoporosis risk. It influences lipid metabolism, decreasing atherosclerosis risk and possibly preventing type II diabetes, with preliminary data suggesting anticarcinogenic effects. Inulin also combats functional constipation and nourishes beneficial gut bacteria to maintain microbiota balance.

Weight Loss details

Stimulates metabolism support

7 people found this helpful

Inulin nourishes beneficial gut bacteria, boosts metabolism, and aids the absorption of minerals such as calcium and magnesium, thus supporting bone health. It helps lower cholesterol and controls appetite while promoting weight loss. Incorporating 1-1.5 teaspoons into my yoghurt yields impressive intestinal regularity, effectively working like clockwork.

Food Poisoning details

Babu US, Sommers K, Harrison LM, Balan KV. Effects of fructooligosaccharide-inulin on Salmonella-killing and inflammatory gene expression in chicken macrophages. Vet Immunol Immunopathol. 2012;149:92. doi:10.1016/j.vetimm.2012.05.003

FOS-inulin aids Salmonella defense

Our study aimed to explore how a prebiotic called fructooligosaccharide (FOS)-inulin affects chickens' ability to combat food poisoning caused by Salmonella Enteritidis (SE). We focused on chicken macrophages, which are important immune cells that help eliminate this pathogen. Using an in vitro model, we treated the HD11 macrophage cell line with FOS-inulin and assessed its ability to phagocytose and kill SE, as well as the production of inflammatory markers.

The results were quite revealing. After treatment with FOS-inulin, we found that the HD11 cells contained significantly fewer viable SE compared to those that were untreated, suggesting that this prebiotic supports macrophage function in eliminating the bacteria. However, it’s worth noting that FOS-inulin did not appear to influence the overall phagocytosis process or the production of nitric oxide, a key player in the immune response.

Additionally, we observed that levels of IL-1β, an important inflammatory cytokine, were significantly reduced in macrophages treated with FOS-inulin. This indicates that FOS-inulin can help modulate the innate immune response, making it potentially beneficial for enhancing the body's defense against foodborne pathogens while also reducing excessive inflammation.

Long-term relief

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8 people found this helpful

This product has improved my constipation, which I have struggled with for 20-30 years. Having only one bowel movement every two to three days, I was in search of effective remedies. Prebiotics are crucial for gut health, and this one pairs well with probiotics, enhancing results. I recommend taking 2-4 teaspoons daily; you’ll notice clear improvements after one or two days!

Irritable Bowel Syndrome details

Questionable

Inulin aids IBS-C symptom management

Bărboi OB, Ciortescu I, Chirilă I, Anton C, Drug V. Effect of inulin in the treatment of irritable bowel syndrome with constipation (Review). Exp Ther Med. 2020;20:185. doi:10.3892/etm.2020.9315

We explored the impact of inulin on irritable bowel syndrome (IBS), particularly focusing on its effect for those suffering from constipation. IBS is a widespread issue that brings significant social and financial burdens.

Our investigation revealed that inulin appears to play a beneficial role in managing symptoms by influencing bowel movements and improving stool consistency. It does this by altering the gut microbiota, which is increasingly recognized as an important factor in gastrointestinal health.

However, while the positive outcomes of inulin for IBS patients with constipation seem promising, more large-scale, randomized clinical trials are necessary to strengthen this evidence. It’s essential to ensure the findings are backed by solid data so that patients can confidently consider inulin as a viable treatment option.

Effective against bowel issues

Most Useful Review

35 people found this helpful

In my experience with dietary supplements, inulin offered a remarkable outcome for my persistent bowel issues. After just a couple of days, I forgot about my belly discomfort. My mother uses a teaspoon daily for complete bowel normalisation. It’s surprisingly economical!

Nausea details

After eating, I experienced no nausea or discomfort, which was quite satisfactory.

Heartburn details

Effective for digestion

Definitely yes! Inulin suits me in all respects. It gently lowers sugar and improves digestion. After taking it, I am not bothered by heaviness in the right hypochondrium, my pancreas does not hurt, and there is no heartburn or belching. I like Inulin for its effectiveness. You cannot find such drugs in a pharmacy. It is a wonderful supplement for the intestines, containing fibre, which aids in constipation relief. The quality of this brand is excellent, and the packaging is convenient, with tangible benefits. In addition, inulin is used to make cheeses, serving as a medium for developing beneficial bacteria. I recommend it!

High Cholesterol details

Wang Y, Nan X, Zhao Y, Jiang L, Wang H, et al. Dietary supplementation with inulin improves lactation performance and serum lipids by regulating the rumen microbiome and metabolome in dairy cows. Anim Nutr. 2021;7:1189. doi:10.1016/j.aninu.2021.09.007

Inulin lowers cholesterol in cows

In our quest to understand the effects of inulin on high cholesterol levels, we explored a study involving sixteen Holstein dairy cows. These cows were divided into two groups, receiving either no inulin or 200 grams of inulin per day over a six-week period. By carefully analyzing the samples collected from milk, serum, and rumen fluid at the end, we discovered some significant findings related to cholesterol.

Notably, supplementing the cows’ diet with inulin resulted in reduced total cholesterol and triglycerides in their serum. Specifically, total cholesterol levels fell by about 8%, and triglycerides decreased by around 10%. The research highlighted that while the milk yield and its quality improved, so did the health of the cows in terms of serum lipid levels.

We also observed that inulin led to changes in the composition of beneficial bacteria within the rumen, which are known to promote health and efficient digestion. This adjustment in gut microbiome may play a crucial role in lowering cholesterol levels, providing a compelling case for the benefits of inulin for managing high cholesterol, particularly in dairy cows.

Overall, the study suggests that incorporating inulin into the diet of dairy cows not only boosts lactation performance but also importantly contributes to lowering cholesterol, presenting a dual benefit for dairy farmers and animal health.

Constipation relief achieved

Most Useful Review

4 people found this helpful

I highly recommend this organic inulin, which nourishes gut bacteria. Most immune cells are concentrated in the gut, so nourishing these bacteria is vital. This inulin has a slight sweetness and easily dissolves in hot water, making it convenient. It has improved my gastrointestinal health significantly, resolving constipation issues effortlessly. If you appreciate my comment, kindly give it a like. Thank you! ☺️

Bloating details

Holscher HD, Doligale JL, Bauer LL, Gourineni V, Pelkman CL, et al. Gastrointestinal tolerance and utilization of agave inulin by healthy adults. Food Funct. 2014;5:1142. doi:10.1039/c3fo60666j

Questionable

Based on 12 Researches

Agave inulin shows mild bloating

We examined the effects of agave inulin on gastrointestinal tolerance, particularly focusing on bloating, in a structured study. This research utilized a randomized, double-blind, placebo-controlled crossover trial, involving 29 healthy adults across three periods, each lasting 21 days with one-week breaks in between.

Participants consumed either 5.0 g or 7.5 g of agave inulin, or a placebo, while we surveyed them for gastrointestinal symptoms. Interestingly, we found that while both doses led to slight increases in bloating and other symptoms like flatulence, the overall intensity remained low on a scale of 0 to 12.

For example, bloating and flatulence were reported slightly more frequently with the inulin, but our scores indicated minimal discomfort. Additionally, we noted improvements in bowel movements, with softer stools and more frequent visits to the bathroom, especially at the higher dosage. Remarkably, diarrhea was not more common with inulin consumption compared to the placebo.

Overall, our findings suggest that while agave inulin can cause some bloating, it's not significant enough to deter its use. Instead, it seems to offer potential benefits in terms of digestive health without major gastrointestinal issues.

Great for digestion

Most Useful Review

35 people found this helpful

I have been taking inulin for six months. After starting this supplement, my stomach improved, and the longstanding bloating ceased. Additionally, my blood sugar levels have decreased. My sister, aged 90, also took inulin and experienced enhancements in her stomach function and overall well-being, reflected in increased energy levels.

Chronic Fatigue Syndrome details

3 people found this helpful

I'm very satisfied with this product. I alternate it with live bacteria, and it’s fantastic! I have irritable bowel syndrome and partial indigestibility, but thanks to inulin, I regularly go to the toilet without discomfort. I love the taste! I prepare it by dissolving spoons in half a glass of water overnight, and I've already purchased three jars!

Headache details

Inulin helps reduce migraines

We conducted a randomized double-blind placebo-controlled trial to explore the impact of inulin supplementation on migraines in women aged 20 to 50. Over the course of 12 weeks, 80 participants were split into two groups: one received 10 grams of inulin daily, while the other received a placebo.

Our findings revealed significant improvements in several migraine characteristics for those taking inulin. Specifically, we observed reductions in the severity, duration, and frequency of headache attacks, as well as improvements in mental health symptoms, such as depression, anxiety, and stress levels. The inulin group experienced a notable drop in their headache impact test scores, indicating a positive shift in their daily lives.

However, it’s important to note that we did not see a significant change in quality of life scores between the two groups. Overall, our study provides compelling evidence that inulin supplementation could be beneficial for women struggling with migraine symptoms, but further research is essential to confirm these findings.

7.5

Less headaches

Most Useful Review

3 people found this helpful

After taking lecithin for 2-3 months, I noticed I felt less tired at work during busy periods, and my headaches became less frequent. The taste is pleasant when mixed with food; I found it easier to take by chewing the powder after or during a meal. I consumed half a teaspoon daily, sometimes a full spoon. I didn’t encounter any side effects.

Diarrhea details