 Garden of Life, MyKind Organics, Organic Plant Calcium, 90 Vegan Tablets | | |
Calcium enhances arthritis therapyHydrolysis of 2D Nanosheets Reverses Rheumatoid Arthritis Through Anti-Inflammation and Osteogenesis. We investigated the potential of 2D layered calcium disilicide nanoparticles (CSNs) to treat rheumatoid arthritis (RA) through their unique properties. CSNs are crafted using a straightforward method of aqueous exfoliation, and their hydrolysis generates several beneficial components including hydrogen gas, alkaline calcium hydroxide (Ca(OH)), and silica.
These components support healing by improving anti-oxidation and reducing inflammation while promoting bone regeneration. The hydrogen gas helps eliminate harmful radicals and can alter macrophage behavior, which is crucial for regulating inflammation. Meanwhile, calcium hydroxide works to balance the acidic environment in the joints, limiting the harmful activity of osteoclasts, the cells that break down bone.
Furthermore, the calcium released can bind with phosphates, aiding in the formation of calcium phosphate, which is essential for bone mineralization. We confirmed these multifaceted benefits through tests on arthritic mice and rabbits, demonstrating that CSNs can provide a promising, biocompatible treatment strategy that enhances therapy beyond just addressing inflammation.
This study emphasizes the importance of calcium and its interactive role in more comprehensive arthritis treatments, fostering both anti-inflammatory and pro-osteogenic effects vital for joint health. Less inflammation Most Useful Review The plant-based calcium and D3 have significantly alleviated my mum's and my inflammation from arthritis and provided an overall sense of wellbeing with quality organic ingredients. |
 Garden of Life, Vitamin Code, RAW Calcium, 120 Vegetarian Capsules | | |
Vitamin D aids rheumatoid arthritisThe role of vitamins D, B12, C, and K in modulating inflammation and disease management in rheumatoid arthritis: a comprehensive review. We explored how vitamin D plays a role in managing rheumatoid arthritis (RA), a condition that causes joint inflammation and discomfort. It's been found that many people with RA often suffer from vitamin D deficiency, which may worsen their symptoms and overall disease severity.
Our review indicates that vitamin D could help modulate immune responses and lower inflammation levels. Supplementing with vitamin D has shown potential in improving various disease activity markers, signaling that it could be a valuable addition to treatment strategies for RA.
Besides vitamin D, we also looked at other important vitamins like B12, C, and K. While vitamin D stands out for its immune benefits, B12 supports energy and neurological health, C helps with collagen production and inflammation reduction, and K contributes to bone health.
Together, these vitamins create a comprehensive approach to managing RA, emphasizing the need for further research to determine the best ways to use them effectively. Recommended for bones Most Useful Review I have taken this supplement for several years due to my knee arthritis. It doesn’t cause any discomfort or constipation, and my digestion is great. I highly recommend it for bone health. |
 Nature's Bounty, Calcium Magnesium Zinc with Vitamin D3, 100 Coated Caplets | | |
Vitamin D aids rheumatoid arthritisThe role of vitamins D, B12, C, and K in modulating inflammation and disease management in rheumatoid arthritis: a comprehensive review. We explored how vitamin D plays a role in managing rheumatoid arthritis (RA), a condition that causes joint inflammation and discomfort. It's been found that many people with RA often suffer from vitamin D deficiency, which may worsen their symptoms and overall disease severity.
Our review indicates that vitamin D could help modulate immune responses and lower inflammation levels. Supplementing with vitamin D has shown potential in improving various disease activity markers, signaling that it could be a valuable addition to treatment strategies for RA.
Besides vitamin D, we also looked at other important vitamins like B12, C, and K. While vitamin D stands out for its immune benefits, B12 supports energy and neurological health, C helps with collagen production and inflammation reduction, and K contributes to bone health.
Together, these vitamins create a comprehensive approach to managing RA, emphasizing the need for further research to determine the best ways to use them effectively. Pain relief Most Useful Review 2 people found this helpful These vitamins REALLY WORK FOR ME! I’ve been taking them for about three weeks and can feel a difference in my body already. I suffer from osteoarthritis, particularly in my knees, and after some research, I found magnesium helps with inflammation. Since starting these vitamins, I've had no pain in my knees or feet and can work longer hours without throbbing pain! |
 Jarrow Formulas, Pantothenic Acid B5, 500 mg, 100 Veggie Caps | | |
Calcium enhances arthritis therapyHydrolysis of 2D Nanosheets Reverses Rheumatoid Arthritis Through Anti-Inflammation and Osteogenesis. We investigated the potential of 2D layered calcium disilicide nanoparticles (CSNs) to treat rheumatoid arthritis (RA) through their unique properties. CSNs are crafted using a straightforward method of aqueous exfoliation, and their hydrolysis generates several beneficial components including hydrogen gas, alkaline calcium hydroxide (Ca(OH)), and silica.
These components support healing by improving anti-oxidation and reducing inflammation while promoting bone regeneration. The hydrogen gas helps eliminate harmful radicals and can alter macrophage behavior, which is crucial for regulating inflammation. Meanwhile, calcium hydroxide works to balance the acidic environment in the joints, limiting the harmful activity of osteoclasts, the cells that break down bone.
Furthermore, the calcium released can bind with phosphates, aiding in the formation of calcium phosphate, which is essential for bone mineralization. We confirmed these multifaceted benefits through tests on arthritic mice and rabbits, demonstrating that CSNs can provide a promising, biocompatible treatment strategy that enhances therapy beyond just addressing inflammation.
This study emphasizes the importance of calcium and its interactive role in more comprehensive arthritis treatments, fostering both anti-inflammatory and pro-osteogenic effects vital for joint health. Long-lasting effects Most Useful Review My husband takes it alongside other medications for rheumatic arthritis. It helps and lasts a long time. I highly recommend it for purchase.   |
 NOW Foods, Pantothenic Acid, 500 mg, 100 Veg Capsules | | |
Calcium enhances arthritis therapyHydrolysis of 2D Nanosheets Reverses Rheumatoid Arthritis Through Anti-Inflammation and Osteogenesis. We investigated the potential of 2D layered calcium disilicide nanoparticles (CSNs) to treat rheumatoid arthritis (RA) through their unique properties. CSNs are crafted using a straightforward method of aqueous exfoliation, and their hydrolysis generates several beneficial components including hydrogen gas, alkaline calcium hydroxide (Ca(OH)), and silica.
These components support healing by improving anti-oxidation and reducing inflammation while promoting bone regeneration. The hydrogen gas helps eliminate harmful radicals and can alter macrophage behavior, which is crucial for regulating inflammation. Meanwhile, calcium hydroxide works to balance the acidic environment in the joints, limiting the harmful activity of osteoclasts, the cells that break down bone.
Furthermore, the calcium released can bind with phosphates, aiding in the formation of calcium phosphate, which is essential for bone mineralization. We confirmed these multifaceted benefits through tests on arthritic mice and rabbits, demonstrating that CSNs can provide a promising, biocompatible treatment strategy that enhances therapy beyond just addressing inflammation.
This study emphasizes the importance of calcium and its interactive role in more comprehensive arthritis treatments, fostering both anti-inflammatory and pro-osteogenic effects vital for joint health. Relieves arthritis pain Most Useful Review The dietary supplement is relatively safe but could be cleaner. Pantothenic acid effectively relieves arthritis pain and supports overall health during illnesses. |
 NOW Foods, Oregano Oil, 90 Softgels | | |
Oregano compound reduces arthritis symptomsA novel heat-shock protein coinducer boosts stress protein Hsp70 to activate T cell regulation of inflammation in autoimmune arthritis. We explored the effects of oregano, specifically its active compound carvacrol, on arthritis. The research aimed to see if boosting heat-shock proteins (HSPs), which help in regulating immune responses, could improve the body’s ability to handle inflammation associated with arthritis.
Through both laboratory and animal studies, we found that carvacrol significantly increased Hsp70 protein levels. This boost in stress proteins led to enhanced T cell responses, which are crucial for fighting inflammation. In practical terms, carvacrol showed an impressive ability to reduce symptoms related to arthritis in mice, helping to maintain a healthy immune response.
Our findings suggest that incorporating carvacrol through dietary means can positively influence how the immune system responds to inflammation. This opens up exciting possibilities for using natural food components in managing autoimmune conditions like arthritis, illustrating the link between diet and immune health. Pain relief observed Most Useful Review 30 people found this helpful Now Foods, Oregano Oil My mother has been using this, and all her pain has subsided in her fingers and toes. She is even giving it to her old dogs for their arthritis, and her vet approved it. She really appreciates this product and has my husband using it as well, who claims it helps him too. |
 NOW Foods, Real Food, Raw Pumpkin Seeds, Unsalted, 16 oz (454 g) | | |
Quercetin reduces arthritis inflammationQuercetin, a Compound of the Total Flavonoids of Schltr., Ameliorates Rheumatoid Arthritis by Targeting TNF-α. In our exploration of how certain natural compounds can impact rheumatoid arthritis (RA), we focused on the total flavonoids derived from Schltr., specifically identifying the effects of quercetin. Our research employed various methods, including cellular and animal models, to examine how these compounds inhibit TNF-α, a key player in inflammation and joint deterioration.
We discovered that quercetin stands out among several compounds, demonstrating a strong ability to reduce TNF-α activity. This reduction corresponds with decreased cellular injury and apoptosis in our models, showcasing quercetin's potential as a protective agent against RA symptoms. Through advanced techniques such as molecular docking and thermal profiling, we verified that quercetin binds to TNF-α, eventually diminishing the inflammatory processes related to arthritis.
The findings suggest that quercetin plays a significant role in suppressing the TNF-α/NF-κB signaling pathway, which is crucial in the development of RA. By blocking certain inflammatory responses, quercetin appears to mitigate pain and joint damage, positioning it as a hopeful candidate for RA treatment. Overall, our investigation highlights quercetin's promising properties as a natural anti-inflammatory agent for those suffering from arthritis. Beneficial for arthritis Most Useful Review 1 people found this helpful The quality is excellent. I have repurchased pumpkin seeds numerous times due to their anti-inflammatory effects, which benefit my periodontal disease and arthritis. They are natural and healthy, making them a long-time staple in my diet. |
 NOW Foods, Niacin, Flush-Free, Double Strength, 500 mg, 180 Veg Capsules | | |
Niacin may lower osteoarthritis riskAssociation between niacin intake and osteoarthritis in the US population based on NHANES 1999-2018. We aimed to understand the relationship between niacin intake and osteoarthritis (OA) by analyzing data from the National Health and Nutrition Examination Survey spanning from 1999 to 2018. With over 30,000 participants in the study and almost 2,000 diagnosed with osteoarthritis, we found some interesting results.
Our analysis used advanced statistical methods to explore how different levels of niacin intake affected the risk of developing OA. What we discovered was that higher niacin intake was consistently associated with a reduced risk of osteoarthritis. In fact, participants in the highest intake group had a remarkable 33% lower risk compared to those in the lowest intake group.
We also noticed that there’s a non-linear relationship; once we reach an inflection point in niacin intake, the way it impacts OA risk changes. The results were particularly striking in Non-Hispanic Black individuals and others in different racial groups.
Overall, this research suggests that by increasing the consumption of niacin-rich foods, we may be able to reduce the risk of developing osteoarthritis. However, further investigations are needed to confirm these findings and explore the potential of niacin as an effective dietary approach to OA prevention and treatment. Provides arthritis relief Most Useful Review 7 people found this helpful Great for arthritis! The flush variety of niacin aids circulation and may reduce allergies. However, I appreciate the non-flush variant as it provides relief from arthritis without the discomfort. I find it essential for my mobility; I can hardly walk without it. It works brilliantly! |
 NOW Foods, Zinc, 50 mg, 250 Tablets | | |
Zinc alleviates arthritis symptomsTherapeutic Dose of Zinc Aspartate and Zinc Citrate Attenuates Disease Activity Indices in Rheumatoid Arthritis. We explored the effects of zinc supplements—specifically zinc aspartate and zinc citrate—on reducing the symptoms of rheumatoid arthritis. In our study, we induced arthritis in male Wistar rats using a collagen-related method and then treated the rats with these zinc compounds over a four-week period. Our objective was to evaluate how these compounds could impact the disease's severity and markers associated with rheumatoid arthritis.
The results were quite promising. Both zinc aspartate and zinc citrate, administered at a therapeutic dose of 50 mg of elemental zinc per day, showed a significant reduction in the clinical symptoms associated with arthritis. Furthermore, these compounds displayed antibacterial properties against Escherichia coli, which is notable since rheumatoid arthritis patients often suffer from increased sensitivity to bacterial infections.
Importantly, we found no adverse effects on liver or kidney function in the rats that received the zinc treatment. This highlights the potential of zinc compounds not only as anti-inflammatory agents but also as preventive measures against microbial growth that can complicate rheumatoid arthritis. Remarkable improvement Most Useful Review 92 people found this helpful My father struggled to get around due to arthritis and eventually needed a walker. After taking this vitamin daily for two weeks, he could walk unaided. My husband also takes this vitamin; whenever he feels unwell, he takes it and within 24 hours, he feels normal again. |
 NOW Foods, Zinc Picolinate, 50 mg, 60 Veg Capsules (50 mg per Capsule) | | |
Zinc alleviates arthritis symptomsTherapeutic Dose of Zinc Aspartate and Zinc Citrate Attenuates Disease Activity Indices in Rheumatoid Arthritis. We explored the effects of zinc supplements—specifically zinc aspartate and zinc citrate—on reducing the symptoms of rheumatoid arthritis. In our study, we induced arthritis in male Wistar rats using a collagen-related method and then treated the rats with these zinc compounds over a four-week period. Our objective was to evaluate how these compounds could impact the disease's severity and markers associated with rheumatoid arthritis.
The results were quite promising. Both zinc aspartate and zinc citrate, administered at a therapeutic dose of 50 mg of elemental zinc per day, showed a significant reduction in the clinical symptoms associated with arthritis. Furthermore, these compounds displayed antibacterial properties against Escherichia coli, which is notable since rheumatoid arthritis patients often suffer from increased sensitivity to bacterial infections.
Importantly, we found no adverse effects on liver or kidney function in the rats that received the zinc treatment. This highlights the potential of zinc compounds not only as anti-inflammatory agents but also as preventive measures against microbial growth that can complicate rheumatoid arthritis. Improved sleep Most Useful Review I purchased these vitamins to strengthen my immune system and support my joints, as I suffer from arthritis. I have recently started taking them and have noticed no negative effects. My sleep has improved, and there’s new hair growth in bald patches. Overall, I’m pleased with the vitamins and would recommend them for arthritis. |
 Jarrow Formulas, Vegan Zinc Balance, 100 Veggie Capsules | | |
Zinc alleviates arthritis symptomsTherapeutic Dose of Zinc Aspartate and Zinc Citrate Attenuates Disease Activity Indices in Rheumatoid Arthritis. We explored the effects of zinc supplements—specifically zinc aspartate and zinc citrate—on reducing the symptoms of rheumatoid arthritis. In our study, we induced arthritis in male Wistar rats using a collagen-related method and then treated the rats with these zinc compounds over a four-week period. Our objective was to evaluate how these compounds could impact the disease's severity and markers associated with rheumatoid arthritis.
The results were quite promising. Both zinc aspartate and zinc citrate, administered at a therapeutic dose of 50 mg of elemental zinc per day, showed a significant reduction in the clinical symptoms associated with arthritis. Furthermore, these compounds displayed antibacterial properties against Escherichia coli, which is notable since rheumatoid arthritis patients often suffer from increased sensitivity to bacterial infections.
Importantly, we found no adverse effects on liver or kidney function in the rats that received the zinc treatment. This highlights the potential of zinc compounds not only as anti-inflammatory agents but also as preventive measures against microbial growth that can complicate rheumatoid arthritis. Healed arthritis Most Useful Review 2 people found this helpful Exellent small and easy to swallow! I have been taking zinc for many years — I've managed to heal my arthritis using only supplements, and zinc is a major mineral in my regimen. |
 Doctor's Best, High Absorption Magnesium, 200 mg, 120 Tablets, (100 mg per Tablet) | | |
Magnesium protects against bone erosionSerum ionized magnesium acts as an independent protective factor against bone erosion in patients with gouty arthritis: a cross-sectional study. We delved into the relationship between magnesium levels and gouty arthritis, a condition known for causing painful flare-ups and damaging joint function. Our research focused on measuring serum ionized magnesium levels in a group of 769 patients and assessing how these levels relate to bone erosion, a serious complication of gout.
Our findings revealed that patients experiencing bone erosion had significantly lower magnesium levels compared to those without erosion. When we categorized magnesium levels into quartiles, the data showed that those in the lowest quartile (Q1) were more likely to have bone erosion compared to patients in higher quartiles. In fact, the prevalence of erosion in the lowest magnesium group was much higher, illustrating a clear connection.
Through detailed analysis, we concluded that higher levels of serum ionized magnesium may serve as a protective factor against bone erosion in gouty arthritis. This suggests that magnesium supplementation could be a promising strategy for individuals suffering from this debilitating condition, potentially helping to slow down or prevent further joint damage. Effective pain relief Most Useful Review 26 people found this helpful I recommend this supplement for arthritis in the knees. After enduring several surgeries and experiencing unbearable pain, I noticed an unbelievable difference just four days after starting this supplement. It provided me with significant relief, better than any painkiller I’ve tried, and restored my knee movement. I truly wish I’d discovered this 40 years ago. |
 NOW Foods, Magnesium Citrate, 400 mg, 120 Veg Capsules (133 mg per Capsule) | | |
Magnesium protects against bone erosionSerum ionized magnesium acts as an independent protective factor against bone erosion in patients with gouty arthritis: a cross-sectional study. We delved into the relationship between magnesium levels and gouty arthritis, a condition known for causing painful flare-ups and damaging joint function. Our research focused on measuring serum ionized magnesium levels in a group of 769 patients and assessing how these levels relate to bone erosion, a serious complication of gout.
Our findings revealed that patients experiencing bone erosion had significantly lower magnesium levels compared to those without erosion. When we categorized magnesium levels into quartiles, the data showed that those in the lowest quartile (Q1) were more likely to have bone erosion compared to patients in higher quartiles. In fact, the prevalence of erosion in the lowest magnesium group was much higher, illustrating a clear connection.
Through detailed analysis, we concluded that higher levels of serum ionized magnesium may serve as a protective factor against bone erosion in gouty arthritis. This suggests that magnesium supplementation could be a promising strategy for individuals suffering from this debilitating condition, potentially helping to slow down or prevent further joint damage. Reduced arthritis pain Most Useful Review 5 people found this helpful I stopped using calcium and now use Magnesium Citrate instead, which was recommended by a friend. My arthritis feels significantly better since I made the switch. |
 NOW Foods, Magnesium Malate, 1,000 mg, 180 Tablets | | |
Magnesium protects against bone erosionSerum ionized magnesium acts as an independent protective factor against bone erosion in patients with gouty arthritis: a cross-sectional study. We delved into the relationship between magnesium levels and gouty arthritis, a condition known for causing painful flare-ups and damaging joint function. Our research focused on measuring serum ionized magnesium levels in a group of 769 patients and assessing how these levels relate to bone erosion, a serious complication of gout.
Our findings revealed that patients experiencing bone erosion had significantly lower magnesium levels compared to those without erosion. When we categorized magnesium levels into quartiles, the data showed that those in the lowest quartile (Q1) were more likely to have bone erosion compared to patients in higher quartiles. In fact, the prevalence of erosion in the lowest magnesium group was much higher, illustrating a clear connection.
Through detailed analysis, we concluded that higher levels of serum ionized magnesium may serve as a protective factor against bone erosion in gouty arthritis. This suggests that magnesium supplementation could be a promising strategy for individuals suffering from this debilitating condition, potentially helping to slow down or prevent further joint damage. Less pain relief Most Useful Review It works well. I have rheumatoid arthritis and I feel less pain when I take magnesium malate. |
 Source Naturals, Magnesium Malate, 3,750 mg, 360 Tablets (1,250 mg per Tablet) | | |
Magnesium protects against bone erosionSerum ionized magnesium acts as an independent protective factor against bone erosion in patients with gouty arthritis: a cross-sectional study. We delved into the relationship between magnesium levels and gouty arthritis, a condition known for causing painful flare-ups and damaging joint function. Our research focused on measuring serum ionized magnesium levels in a group of 769 patients and assessing how these levels relate to bone erosion, a serious complication of gout.
Our findings revealed that patients experiencing bone erosion had significantly lower magnesium levels compared to those without erosion. When we categorized magnesium levels into quartiles, the data showed that those in the lowest quartile (Q1) were more likely to have bone erosion compared to patients in higher quartiles. In fact, the prevalence of erosion in the lowest magnesium group was much higher, illustrating a clear connection.
Through detailed analysis, we concluded that higher levels of serum ionized magnesium may serve as a protective factor against bone erosion in gouty arthritis. This suggests that magnesium supplementation could be a promising strategy for individuals suffering from this debilitating condition, potentially helping to slow down or prevent further joint damage. Pain management success Most Useful Review I consistently use this magnesium as it significantly reduces the pain associated with my rheumatoid arthritis. |
 NOW Foods, Magnesium Caps, 400 mg, 180 Veg Capsules | | |
Magnesium protects against bone erosionSerum ionized magnesium acts as an independent protective factor against bone erosion in patients with gouty arthritis: a cross-sectional study. We delved into the relationship between magnesium levels and gouty arthritis, a condition known for causing painful flare-ups and damaging joint function. Our research focused on measuring serum ionized magnesium levels in a group of 769 patients and assessing how these levels relate to bone erosion, a serious complication of gout.
Our findings revealed that patients experiencing bone erosion had significantly lower magnesium levels compared to those without erosion. When we categorized magnesium levels into quartiles, the data showed that those in the lowest quartile (Q1) were more likely to have bone erosion compared to patients in higher quartiles. In fact, the prevalence of erosion in the lowest magnesium group was much higher, illustrating a clear connection.
Through detailed analysis, we concluded that higher levels of serum ionized magnesium may serve as a protective factor against bone erosion in gouty arthritis. This suggests that magnesium supplementation could be a promising strategy for individuals suffering from this debilitating condition, potentially helping to slow down or prevent further joint damage. Pain disappearance Most Useful Review 4 people found this helpful Magnesium supplementation is essential! It supports the nervous system, cardiovascular system, and cartilage system. For those with joint pain, this is a miracle supplement. My aunt suffers from osteoarthritis, but after taking magnesium daily, her pain has disappeared. I highly recommend it! |
 NOW Foods, Turmeric Curcumin Phytosome With Meriva, 500 mg, 60 Veg Capsules | | |
Curcumin reduces osteoarthritis severityCurcumin alleviates osteoarthritis in mice by suppressing osteoclastogenesis in subchondral bone via inhibiting NF-κB/JNK signaling pathway. We investigated how curcumin, the active compound in turmeric, impacts osteoarthritis (OA) by focusing on its role in reducing the formation of bone-destroying cells called osteoclasts. In our research, we used a mouse model designed to mimic OA by destabilizing the medial meniscus, allowing us to measure the effects of curcumin on joint health.
Our study included three groups of male mice: those who received a vehicle treatment after their surgery, those with OA but also receiving the vehicle, and those with OA that were treated with curcumin. Over the course of eight weeks, we monitored the mice's cartilage and bone structure, looking for any changes.
We found that curcumin significantly suppressed osteoclast formation and bone resorption without harming the cells, suggesting it may be a promising treatment to alleviate arthritis symptoms. Specifically, curcumin inhibited the activation of important signaling pathways that promote osteoclast formation and cartilage degradation. This suggests a new and exciting approach for treating osteoarthritis, offering hope for better management of this chronic condition. Pain relief Most Useful Review 37 people found this helpful Fantastic supplement for arthritis sufferers! I have rheumatoid arthritis in my wrists and knees. I've taken Jarrow and Now brands Curcumin for months, which has significantly reduced my pain and flare-ups. I recently tried the Bio form of Curcumin, and it felt miraculous. Post-taking, I experienced a surge in energy, but beware of overdoing it as I did. Thanks iHerb for the great prices and fresh supplements. |
 Garden of Life, Turmeric, Maximum Strength, 30 Vegan Tablets | | |
Curcumin reduces osteoarthritis severityCurcumin alleviates osteoarthritis in mice by suppressing osteoclastogenesis in subchondral bone via inhibiting NF-κB/JNK signaling pathway. We investigated how curcumin, the active compound in turmeric, impacts osteoarthritis (OA) by focusing on its role in reducing the formation of bone-destroying cells called osteoclasts. In our research, we used a mouse model designed to mimic OA by destabilizing the medial meniscus, allowing us to measure the effects of curcumin on joint health.
Our study included three groups of male mice: those who received a vehicle treatment after their surgery, those with OA but also receiving the vehicle, and those with OA that were treated with curcumin. Over the course of eight weeks, we monitored the mice's cartilage and bone structure, looking for any changes.
We found that curcumin significantly suppressed osteoclast formation and bone resorption without harming the cells, suggesting it may be a promising treatment to alleviate arthritis symptoms. Specifically, curcumin inhibited the activation of important signaling pathways that promote osteoclast formation and cartilage degradation. This suggests a new and exciting approach for treating osteoarthritis, offering hope for better management of this chronic condition. Reduces inflammation Most Useful Review 3 people found this helpful Perfectly, I have been taking this for over two years before bed. It genuinely helps with my arthritis pain and other joint discomfort, allowing me to sleep soundly. This formula is also antioxidant-rich and contains fantastic ingredients. I recommend it for reducing inflammation in your body and improving your well-being. The package is designed for a month’s supply. |
 Jarrow Formulas, Curcumin 95, Turmeric Extract, 500 mg, 120 Veggie Capsules | | |
Curcumin reduces osteoarthritis severityCurcumin alleviates osteoarthritis in mice by suppressing osteoclastogenesis in subchondral bone via inhibiting NF-κB/JNK signaling pathway. We investigated how curcumin, the active compound in turmeric, impacts osteoarthritis (OA) by focusing on its role in reducing the formation of bone-destroying cells called osteoclasts. In our research, we used a mouse model designed to mimic OA by destabilizing the medial meniscus, allowing us to measure the effects of curcumin on joint health.
Our study included three groups of male mice: those who received a vehicle treatment after their surgery, those with OA but also receiving the vehicle, and those with OA that were treated with curcumin. Over the course of eight weeks, we monitored the mice's cartilage and bone structure, looking for any changes.
We found that curcumin significantly suppressed osteoclast formation and bone resorption without harming the cells, suggesting it may be a promising treatment to alleviate arthritis symptoms. Specifically, curcumin inhibited the activation of important signaling pathways that promote osteoclast formation and cartilage degradation. This suggests a new and exciting approach for treating osteoarthritis, offering hope for better management of this chronic condition. Relieves joint pain Most Useful Review 25 people found this helpful This curcumin product is excellent for managing joint pain from arthritis. I wholeheartedly recommend it. |
 Garden of Life, Organics, Extra Strength Turmeric, Inflammatory Response, 60 Vegan Tablets | | |
Curcumin reduces osteoarthritis severityCurcumin alleviates osteoarthritis in mice by suppressing osteoclastogenesis in subchondral bone via inhibiting NF-κB/JNK signaling pathway. We investigated how curcumin, the active compound in turmeric, impacts osteoarthritis (OA) by focusing on its role in reducing the formation of bone-destroying cells called osteoclasts. In our research, we used a mouse model designed to mimic OA by destabilizing the medial meniscus, allowing us to measure the effects of curcumin on joint health.
Our study included three groups of male mice: those who received a vehicle treatment after their surgery, those with OA but also receiving the vehicle, and those with OA that were treated with curcumin. Over the course of eight weeks, we monitored the mice's cartilage and bone structure, looking for any changes.
We found that curcumin significantly suppressed osteoclast formation and bone resorption without harming the cells, suggesting it may be a promising treatment to alleviate arthritis symptoms. Specifically, curcumin inhibited the activation of important signaling pathways that promote osteoclast formation and cartilage degradation. This suggests a new and exciting approach for treating osteoarthritis, offering hope for better management of this chronic condition. Improves joint mobility Most Useful Review 8 people found this helpful Excellent composition! I drank this for a month due to my rheumatoid arthritis, and my SOE dropped significantly, leading to less pain and improved joint mobility. I almost forget my joint issues now! |
 NOW Foods, Turmeric & Bromelain, 90 Veg Capsules | | |
Bromelain shows promise against arthritisExploration of bromelain laden nanostructured lipid carriers: An oral platform for bromelain delivery in rheumatoid arthritis management. We explored a new way to deliver bromelain, a natural enzyme, using nanostructured lipid carriers (Br-NCs).
Our research aimed to improve bromelain's stability and effectiveness in managing rheumatoid arthritis.
The study showed that Br-NCs significantly reduced joint swelling and stiffness in preclinical trials.
These carriers also enhanced bromelain's shelf-life and showed promise as a novel treatment option for arthritis. Pain relief achieved Most Useful Review 2 people found this helpful It’s effective! Since I began taking this dietary supplement not long ago, I have already noticed a difference. My rheumatoid arthritis pain has diminished, and my hands are functioning better. The discomfort from rheumatism has subsided. However, I didn’t like that the capsules do have a slight wakefulness effect. The powder inside is yellow, reminiscent of turmeric. |
 NOW Foods, Turmeric Curcumin Gels, 475 mg, 120 Softgels | | |
Supports joint health Most Useful Review Fine turmeric curcumin capsules are well-regarded for their anti-inflammatory and antioxidant properties. Many users report enhanced overall health, particularly those with joint issues. Curcumin aids in reducing joint pain and inflammation, making it beneficial for those with arthritis. The capsules are more convenient than pure turmeric but require piperine for better absorption. Notably, some users find the effects noticeable only after several weeks of regular intake. Overall, these capsules are seen as an effective, natural remedy for joint health. Highly recommended Most Useful Review Great product from a reliable manufacturer with good quality, and the capsules are easy to swallow. Having bought it for arthritis, I experienced significant relief. I highly recommend it. |
 Solgar, Turmeric Root Extract, 400 mg, 60 Vegetable Capsules | | |
Tremendous help Most Useful Review My husband suffers from arthritis, and this turmeric has been tremendously helpful for him. It alleviates his pain, and he is very satisfied with this product. Muscle inflammation aid Most Useful Review Excellent for arthritis and muscle inflammation. |
 Herb Pharm, Turmeric, 616 mg, 1 fl oz (30 ml) | | |
Pain relief Most Useful Review 4 people found this helpful I began using turmeric extract years ago for my arthritis pain in my hips. The pain has vanished, and I continue to take it for maintenance. It also boosts my immune system and keeps me well. Each evening, I consume one eye dropper of the turmeric extract in a cup with honey and non-dairy milk. It helps me achieve a peaceful sleep. Effective for hands Most Useful Review 1 people found this helpful מצוין! It really helps with my arthritis in my hands and is easy to use in a hot beverage. |
 Himalaya, Turmeric 95 with Curcumin, 60 Vegetarian Capsules | | |
Pain relief noted Most Useful Review 10 people found this helpful Omsk High quality turmeric from the well-known brand Himalaya acts as an anti-inflammatory agent, effective not just for joints. It significantly alleviated my pain, including rheumatoid arthritis. The swelling in my hands has subsided - the pain has ceased. I took it for two months continuously and will definitely use it again in six months! I highly recommend it!!! Joint pain relief Most Useful Review 2 people found this helpful My husband and I have been taking it regularly for a few weeks, and we've genuinely noticed the benefits. Inflammations, aches, and pains have lessened, and there's no more bloating. I sent some to my mother-in-law, and she has experienced improvements in her joint pains from arthritis. We're now recommending it to all our friends! |
 NOW Foods, Magnesium & Calcium, 250 Tablets | | |
Magnesium protects against bone erosionSerum ionized magnesium acts as an independent protective factor against bone erosion in patients with gouty arthritis: a cross-sectional study. We delved into the relationship between magnesium levels and gouty arthritis, a condition known for causing painful flare-ups and damaging joint function. Our research focused on measuring serum ionized magnesium levels in a group of 769 patients and assessing how these levels relate to bone erosion, a serious complication of gout.
Our findings revealed that patients experiencing bone erosion had significantly lower magnesium levels compared to those without erosion. When we categorized magnesium levels into quartiles, the data showed that those in the lowest quartile (Q1) were more likely to have bone erosion compared to patients in higher quartiles. In fact, the prevalence of erosion in the lowest magnesium group was much higher, illustrating a clear connection.
Through detailed analysis, we concluded that higher levels of serum ionized magnesium may serve as a protective factor against bone erosion in gouty arthritis. This suggests that magnesium supplementation could be a promising strategy for individuals suffering from this debilitating condition, potentially helping to slow down or prevent further joint damage. Saved me Most Useful Review This excellent magnesium has been a lifesaver for my arthritis. I frequently called an ambulance due to seizures, but this supplement has made a huge difference. After trying another option from the pharmacy that didn’t work, I’ll definitely order more. I can now live calmly, knowing this magnesium is helping me. |
 Solgar, Calcium Magnesium Plus Zinc, 250 Tablets | | |
Magnesium protects against bone erosionSerum ionized magnesium acts as an independent protective factor against bone erosion in patients with gouty arthritis: a cross-sectional study. We delved into the relationship between magnesium levels and gouty arthritis, a condition known for causing painful flare-ups and damaging joint function. Our research focused on measuring serum ionized magnesium levels in a group of 769 patients and assessing how these levels relate to bone erosion, a serious complication of gout.
Our findings revealed that patients experiencing bone erosion had significantly lower magnesium levels compared to those without erosion. When we categorized magnesium levels into quartiles, the data showed that those in the lowest quartile (Q1) were more likely to have bone erosion compared to patients in higher quartiles. In fact, the prevalence of erosion in the lowest magnesium group was much higher, illustrating a clear connection.
Through detailed analysis, we concluded that higher levels of serum ionized magnesium may serve as a protective factor against bone erosion in gouty arthritis. This suggests that magnesium supplementation could be a promising strategy for individuals suffering from this debilitating condition, potentially helping to slow down or prevent further joint damage. High-quality supplement Most Useful Review The quality is high, and the quantity is substantial; it has helped me significantly with arthritis. |
 NOW Foods, Calcium & Magnesium, 250 Tablets | | |
Magnesium protects against bone erosionSerum ionized magnesium acts as an independent protective factor against bone erosion in patients with gouty arthritis: a cross-sectional study. We delved into the relationship between magnesium levels and gouty arthritis, a condition known for causing painful flare-ups and damaging joint function. Our research focused on measuring serum ionized magnesium levels in a group of 769 patients and assessing how these levels relate to bone erosion, a serious complication of gout.
Our findings revealed that patients experiencing bone erosion had significantly lower magnesium levels compared to those without erosion. When we categorized magnesium levels into quartiles, the data showed that those in the lowest quartile (Q1) were more likely to have bone erosion compared to patients in higher quartiles. In fact, the prevalence of erosion in the lowest magnesium group was much higher, illustrating a clear connection.
Through detailed analysis, we concluded that higher levels of serum ionized magnesium may serve as a protective factor against bone erosion in gouty arthritis. This suggests that magnesium supplementation could be a promising strategy for individuals suffering from this debilitating condition, potentially helping to slow down or prevent further joint damage. Significant pain relief Most Useful Review 14 people found this helpful Very effective calcium! I've previously tried pharmaceutical calcium products, but this one truly surprised me. I took it with vitamin D3 for my knee and hip joint issues stemming from a meniscus operation. After consuming half a jar, I experienced incredible relief. I used to hobble, but now I can run slowly every day. The frequent pain has vanished, and I’m delighted. Despite scepticism towards reviews like this, I’m now sharing my own. I’ve forgotten about my arthritis and took this for myself as well. |
 Life Extension, Bio-Quercetin, 30 Vegetarian Capsules | | |
Quercetin nanoparticles reduce senescenceNanoparticle-delivered quercetin exhibits enhanced efficacy in eliminating iron-overloaded senescent chondrocytes. We explored the effects of quercetin, a natural compound with potential benefits for treating osteoarthritis (OA), specifically focusing on its ability to target damaged chondrocytes, the cartilage cells that play a crucial role in joint health. In our study, we utilized specialized nanoparticles to increase the effectiveness of quercetin, overcoming its usual limitations related to absorption and bioavailability.
Our research involved subjecting human chondrocytes to conditions that mimic OA. Afterward, we treated them with either free quercetin or our quercetin-loaded nanoparticles (Q-NP). We found that the Q-NP not only allowed for better cellular absorption but also selectively induced apoptosis, or programmed cell death, in senescent chondrocytes. This is significant because eliminating these unhealthy cells could pave the way for healthier joint repair and function.
In addition to promoting cell death in the right cells, Q-NP led to an increase in oxidative stress and reduced key markers of cellular aging. We also noted that the treatment halted the cell cycle in cells that needed to be eliminated. Overall, our findings suggest that enhancing quercetin delivery through nanoparticles holds great promise for improving osteoarthritis outcomes by actively removing harmful senescent cells from joint tissues. Pain relief observed Most Useful Review 1 people found this helpful I purchased this for my children’s arthritis. Combining it with other arthritis supplements has significantly reduced their pain, particularly during the worst mornings. I struggled to hold a cup of coffee due to the pain, but now I experience none. I'm hopeful for further improvement and will certainly repurchase. |
 NOW Foods, Quercetin with Bromelain, 120 Veg Capsules | | |
Quercetin nanoparticles reduce senescenceNanoparticle-delivered quercetin exhibits enhanced efficacy in eliminating iron-overloaded senescent chondrocytes. We explored the effects of quercetin, a natural compound with potential benefits for treating osteoarthritis (OA), specifically focusing on its ability to target damaged chondrocytes, the cartilage cells that play a crucial role in joint health. In our study, we utilized specialized nanoparticles to increase the effectiveness of quercetin, overcoming its usual limitations related to absorption and bioavailability.
Our research involved subjecting human chondrocytes to conditions that mimic OA. Afterward, we treated them with either free quercetin or our quercetin-loaded nanoparticles (Q-NP). We found that the Q-NP not only allowed for better cellular absorption but also selectively induced apoptosis, or programmed cell death, in senescent chondrocytes. This is significant because eliminating these unhealthy cells could pave the way for healthier joint repair and function.
In addition to promoting cell death in the right cells, Q-NP led to an increase in oxidative stress and reduced key markers of cellular aging. We also noted that the treatment halted the cell cycle in cells that needed to be eliminated. Overall, our findings suggest that enhancing quercetin delivery through nanoparticles holds great promise for improving osteoarthritis outcomes by actively removing harmful senescent cells from joint tissues. Significant relief Most Useful Review 119 people found this helpful Quercetin and bromelain are potent natural ingredients that alleviate allergic and inflammatory disorders, including arthritis. They help mitigate asthma, eczema, and other conditions. As someone suffering from arthritis, Raynaud's syndrome, and various allergies, I find Quercetin a real lifesaver. I take it regularly and wholeheartedly recommend it! |
 NOW Foods, Glutathione, 500 mg, 60 Veg Capsules | | |
Silymarin shows anti-arthritis potentialAnti-inflammatory and anti-arthritic activities of silymarin acting through inhibition of 5-lipoxygenase. We evaluated the anti-inflammatory and anti-arthritic properties of silymarin, derived from the Silybum marianum plant. In our study, we found that silymarin significantly reduced inflammation and arthritis symptoms in rat models. The research suggests that this effect occurs through the inhibition of a specific enzyme, 5-lipoxygenase.
While these results showcase the potential of silymarin, it's important to note that further research is needed to fully understand its effectiveness in humans. Knee pain relief Most Useful Review 6 people found this helpful I'm delighted to share my review on the 30 tablets I purchased. The results were so impressive that I ordered another 60 tablets. Initially bought to improve my skin, I noticed after about 15 days that my knee pain, shoulder pain related to osteoarthritis, and resting pain in my shoulder blades and arms from cervical spondylotic radiculopathy completely disappeared. I was astonished by the unexpected effects of the glutathione and peony mochi! While I still feel some pain when moving, the resting pain has vanished, allowing me to sleep very well. My hands have also become much fairer. |
 21st Century, Calcium Citrate + D3 Maximum, 75 Tablets | | |
Vitamin D3's role in OA prevention1,25-Dihydroxyvitamin D Deficiency Accelerates Aging-related Osteoarthritis via Downregulation of Sirt1 in Mice. We explored the link between vitamin D3 and knee osteoarthritis (OA) by examining both young and older mice. Our findings revealed that a deficiency in vitamin D3, specifically the active form known as 1,25(OH)D, significantly sped up the development of age-related OA. This included issues such as cartilage damage and increased chondrocyte senescence.
When we supplemented with vitamin D3, we were pleased to see a reversal of these negative changes in OA phenotypes among the test mice. It not only improved cartilage health but also countered oxidative stress and cell aging associated with OA.
Our research highlights the important role of vitamin D3 in maintaining joint health and its potential to help prevent or slow down the onset of OA through mechanisms involving Sirt1, a gene linked to aging and cellular health. This suggests that ensuring sufficient levels of vitamin D3 could be a useful strategy for those at risk of developing arthritis. Helps with osteoarthritis Most Useful Review Excellent! This citrate formula genuinely aids with osteoarthritis. I buy it regularly; however, it's disappointing that the 1kg cans have been discontinued, leaving only smaller sizes available. |
 NOW Foods, C-1000 with Bioflavonoids, 250 Veg Capsules | | |
Vitamin C's role in arthritis managementThe role of vitamins D, B12, C, and K in modulating inflammation and disease management in rheumatoid arthritis: a comprehensive review. We explored the role of vitamin C in addressing arthritis symptoms, particularly its effect on joint inflammation. Vitamin C is known for its antioxidant properties, and we found that it plays a crucial role in collagen synthesis. This feature is important as collagen forms the structural basis of our joints.
What excited us was the possibility that vitamin C could help reduce inflammation in patients with rheumatoid arthritis. Given that inflammation is a major factor in the discomfort and damage associated with this condition, any reduction could significantly enhance the quality of life for those affected.
However, while vitamin C shows promise due to its supportive functions, we must remember that the evidence concerning its direct effectiveness on arthritis specifically is still evolving. The correlation between vitamin C intake and reduced joint inflammation points to a beneficial role, but more detailed studies are necessary to solidify these findings and determine optimal dosages.
Overall, our review highlights that while vitamin C may indeed support joint health and aid in managing inflammation, further research is essential to fully understand its impact and to evaluate how it can be integrated into arthritis management strategies effectively. Joint pain relief Most Useful Review 1 people found this helpful In one capsule, not only essential vitamin C, but also rutin and bioflavonoids. Rutin is known for its protective role for ascorbic acid (vitamin C) due to its antioxidant properties, which fend off excessive oxidation. Preparations from sophora are recommended for strengthening blood vessels. I have arthritis and can definitely say that my joints have become much less painful. This vitamin is particularly useful during heightened virus activity. My whole family takes it as an additional source of body protection, and we rarely suffer from respiratory illnesses. I appreciate the convenient dosage and reasonable pricing of this company's products, and I wholeheartedly recommend it. |
 NOW Foods, E-400 with Mixed Tocopherols, 268 mg (400 IU), 100 Softgels | | |
Reduces arthritis risks Most Useful Review Vitamin E is a powerful antioxidant that protects cells from oxidative damage. It strengthens the immune system, protects cells from premature ageing, reduces inflammation, and may lower the risk of diseases linked to oxidative stress, including arthritis, cataracts, and Alzheimer's disease. Supports arthritis treatment Most Useful Review Since I have rheumatoid arthritis, I always take vitamin E. |
 NOW Foods, MK-7 Vitamin K-2 , 100 mcg, 120 Veg Capsules | | |
No signs of arthritis Most Useful Review A great product! I have been using vitamin K2 (MK7) for many years and recommend it for maintaining low calcium levels in the blood by supporting its return to the bones and teeth. At age 77, I have no signs of arthritis. Safe and effective Most Useful Review I recommend using it with a prescription. It is safe and tremendously beneficial for my arthritis and bones. The package is of excellent size and high quality. |
 NOW Foods, Garlic Oil, 1,500 mg, 250 Softgels | | |
Garlic exosomes benefit osteoarthritisGarlic-derived Exosomes Alleviate Osteoarthritis Through Inhibiting the MAPK Signaling Pathway. In our exploration of garlic's potential benefits for arthritis, we focused on a type of tiny particle called garlic-derived exosomes (GDEs). These particles come from garlic and have shown promise in reducing inflammation in various health issues. We specifically examined how they affect osteoarthritis (OA), a condition that impacts millions by causing joint pain and stiffness.
Our study involved both laboratory and animal models. We treated chondrocytes, the cells in cartilage, with a pro-inflammatory substance while exposing them to GDEs. We found that the garlic-derived particles helped to boost the levels of beneficial cartilage components while inhibiting harmful enzymes that break down cartilage. Additionally, GDEs appeared to reduce the activity of key signaling pathways related to inflammation.
On the animal side, we used a surgical model to simulate OA and injected GDEs directly into the knee joints of mice. The results were encouraging; the GDEs alleviated pain and improved how the mice moved. Histological examinations revealed less joint destruction, suggesting that these garlic particles could indeed help slow the progression of OA without causing toxicity.
Overall, our findings indicate that garlic-derived exosomes hold potential as a treatment for osteoarthritis, making it a significant area for future research into disease-modifying therapies. Consistently excellent Most Useful Review Excellent product and service, as always. It's particularly beneficial for managing my arthritis. |
 Doctor's Best, High Absorption CoQ10 with BioPerine®, 100 mg, 120 Veggie Caps | | |
CoQ10 shows promise for RAEffects of coenzyme Q10 supplementation on matrix metalloproteinases and DAS-28 in patients with rheumatoid arthritis: a randomized, double-blind, placebo-controlled clinical trial. We explored the effects of Coenzyme Q10 (CoQ10) supplementation on rheumatoid arthritis (RA) patients in a well-structured study. Fifty-four individuals diagnosed with RA were divided into two groups: one received 100 mg of CoQ10 daily, while the other group received a placebo for two months. This randomized and double-blind setup helped ensure that the findings would be credible and free from bias.
Our findings revealed some noteworthy changes in the CoQ10 group. There was a significant reduction in serum levels of matrix metalloproteinase-3 (MMP-3), which is linked to inflammation and tissue remodeling, alongside improvements in clinical indicators like swollen joint count and the disease activity score (DAS-28). Essentially, participants taking CoQ10 experienced a decrease in pain levels and tenderness in their joints, suggesting that CoQ10 may offer additional benefits for managing RA symptoms.
However, the study also showed slight improvements in the placebo group, indicating that factors like natural variability and placebo effects could play a role in treatment outcomes. While CoQ10 touted some advantages over the placebo, the reduction in MMP-3 levels signifies a potentially therapeutic area worth further exploration.
In conclusion, CoQ10 may serve as a complementary approach for those dealing with the challenges of rheumatoid arthritis, supporting both clinical symptoms and biomarkers of inflammation. Significant improvement Most Useful Review 4 people found this helpful This product is excellent, particularly for the elderly and those with arthritis and muscle inflammation. After suffering from widespread pain in my back and joints, my condition improved significantly after taking it for over a month. I take 200 mg per day with breakfast and recommend it strongly. |
 Doctor's Best, High Potency Serrapeptase, 120,000 SPU, 270 Veggie Caps | | |
Improves mobility Most Useful Review 120 people found this helpful I included enzyme therapy in my book on chronic illness. Serrapeptase, a powerful anti-inflammatory, has noticeably improved my knee joint mobility and reduced chronic inflammation after six weeks. I appreciate the potency and value of this product, which has proven effective against issues like arthritis. Relieves joint pain Most Useful Review 34 people found this helpful Taking Serrapeptase with Bromelain and Nattokinase has been transformative for my rheumatoid arthritis. The quality and dosage of these supplements are excellent, and I've experienced a significant reduction in pain after a couple of weeks. I wholeheartedly recommend these for anyone seeking relief. |
 Doctor's Best, Nattokinase, 2,000 FUs, 270 Veggie Caps | | |
Pain reduction achieved Most Useful Review 34 people found this helpful I'm taking nattokinase alongside Serrapeptase and Bromelain three times a day away from food; these have become my best allies in battling rheumatoid arthritis. The quality, size, and dosage of these products are excellent. After a few weeks, my pain subsided, and I wholeheartedly recommend them. You'll soon notice the benefits and return to a normal life. Pain relief noted Most Useful Review This product is of excellent quality. When used alongside serrapeptase and curcumin, it alleviates bone pain and reduces inflammation linked to arthritis. Additionally, vitamin D3 enhances the effects. |
 NOW Foods, Boron, 3 mg, 250 Veg Capsules | | |
AN3485 shows promise for arthritisInhibition of Toll-like receptor-mediated inflammation in vitro and in vivo by a novel benzoxaborole. We investigated the effectiveness of a novel compound, AN3485, on inflammation linked to arthritis. By administering AN3485 to mice, we discovered that it significantly reduced key inflammatory markers involved in arthritis over a 20-day period.
Our results showed that the compound successfully inhibited several pro-inflammatory cytokines, thus demonstrating its potential as a treatment for arthritis.
Overall, AN3485 may offer a promising pathway for managing arthritis and other inflammatory conditions. Minimises arthritis effects Most Useful Review 3 people found this helpful I take Boron to reduce the effects of arthritis, primarily in my hands. It appears to be effective where nothing else has helped. The delivery was timely as I was running low on capsules. It’s a good quality product, and Boron, being a mineral, is essential. |
 NOW Foods, Milk Thistle Extract with Turmeric, 150 mg, 120 Veg Capsules | | |
Silymarin shows anti-arthritis potentialAnti-inflammatory and anti-arthritic activities of silymarin acting through inhibition of 5-lipoxygenase. We evaluated the anti-inflammatory and anti-arthritic properties of silymarin, derived from the Silybum marianum plant. In our study, we found that silymarin significantly reduced inflammation and arthritis symptoms in rat models. The research suggests that this effect occurs through the inhibition of a specific enzyme, 5-lipoxygenase.
While these results showcase the potential of silymarin, it's important to note that further research is needed to fully understand its effectiveness in humans. Enhances joint mobility Most Useful Review Curcumin may alleviate pain and enhance joint mobility in those with arthritis. Furthermore, turmeric may aid digestion by stimulating bile production and breaking down fats efficiently. |
 NOW Foods, Milk Thistle Extract, Double Strength, 300 mg, 200 Veg Capsules | | |
Silymarin shows anti-arthritis potentialAnti-inflammatory and anti-arthritic activities of silymarin acting through inhibition of 5-lipoxygenase. We evaluated the anti-inflammatory and anti-arthritic properties of silymarin, derived from the Silybum marianum plant. In our study, we found that silymarin significantly reduced inflammation and arthritis symptoms in rat models. The research suggests that this effect occurs through the inhibition of a specific enzyme, 5-lipoxygenase.
While these results showcase the potential of silymarin, it's important to note that further research is needed to fully understand its effectiveness in humans. Reduced pain effectively Most Useful Review 8 people found this helpful Working. I have to take various supplements and medications due to arthritis. It's tough on my liver, but after a week of this product, I noticed a reduction in both weight and pain. I recommend it. |
 Jarrow Formulas, Vegan Hyaluronic Acid, 120 mg, 60 Veggie Capsules (60 mg per Capsule) | | |
Hyaluronic acid eases shoulder arthritisRetrospective evaluation of the efficacy of ultrasound-guided intra-articular hyaluronic-acid-based injections (Hyalubrix) in patients with glenohumeral osteoarthritis. We explored the impact of hyaluronic acid (HA) injections, specifically a formulation called Hyalubrix®, on patients suffering from glenohumeral osteoarthritis (GH-OA). The condition often leads to painful and disabling shoulder issues, and we aimed to find out if these injections could provide relief and improve overall quality of life.
By analyzing data collected from standard clinical practice, we focused on how patients rated their pain and shoulder function. Tools such as the Simple Shoulder Test and the Euro-Quality of Life Health Assessment allowed us to track their progress over time. We observed that more than half of the patients reported complete pain relief, while nearly 28% experienced a significant decrease in their discomfort. Such improvements led to noticeable boosts in overall joint function and quality of life.
Our findings affirm that hyaluronic acid injections can be a highly beneficial treatment option for individuals grappling with GH-OA. The positive responses from patients highlight the potential of this therapy to enhance not just physical function but also daily living. Knee pain relief Most Useful Review 11 people found this helpful This product helps relieve knee pain from arthritis. It works remarkably well. |
 NOW Foods, Hyaluronic Acid, Double Strength, 100 mg, 60 Veg Capsules | | |
Hyaluronic acid eases shoulder arthritisRetrospective evaluation of the efficacy of ultrasound-guided intra-articular hyaluronic-acid-based injections (Hyalubrix) in patients with glenohumeral osteoarthritis. We explored the impact of hyaluronic acid (HA) injections, specifically a formulation called Hyalubrix®, on patients suffering from glenohumeral osteoarthritis (GH-OA). The condition often leads to painful and disabling shoulder issues, and we aimed to find out if these injections could provide relief and improve overall quality of life.
By analyzing data collected from standard clinical practice, we focused on how patients rated their pain and shoulder function. Tools such as the Simple Shoulder Test and the Euro-Quality of Life Health Assessment allowed us to track their progress over time. We observed that more than half of the patients reported complete pain relief, while nearly 28% experienced a significant decrease in their discomfort. Such improvements led to noticeable boosts in overall joint function and quality of life.
Our findings affirm that hyaluronic acid injections can be a highly beneficial treatment option for individuals grappling with GH-OA. The positive responses from patients highlight the potential of this therapy to enhance not just physical function but also daily living. Effective for arthritis Most Useful Review 102 people found this helpful A worthy competitor to medicinal chondroprotectors! The order arrived in 4 days, well packed, with the product matching the description and expiry date. The capsules are medium-sized, easy to take, and have a yeasty smell. I find this medication beneficial for my arthritis; the crunch in my knee joint disappears, and any discomfort subsides during exertion. My skin feels more hydrated, and fine wrinkles are less apparent. The convenient dosage of 100mg, when combined with adequate hydration and vitamin C, proves effective. |
 Doctor's Best, Hyaluronic Acid + Chondroitin Sulfate with BioCell Collagen, 180 Veggie Capsules | | |
Hyaluronic acid eases shoulder arthritisRetrospective evaluation of the efficacy of ultrasound-guided intra-articular hyaluronic-acid-based injections (Hyalubrix) in patients with glenohumeral osteoarthritis. We explored the impact of hyaluronic acid (HA) injections, specifically a formulation called Hyalubrix®, on patients suffering from glenohumeral osteoarthritis (GH-OA). The condition often leads to painful and disabling shoulder issues, and we aimed to find out if these injections could provide relief and improve overall quality of life.
By analyzing data collected from standard clinical practice, we focused on how patients rated their pain and shoulder function. Tools such as the Simple Shoulder Test and the Euro-Quality of Life Health Assessment allowed us to track their progress over time. We observed that more than half of the patients reported complete pain relief, while nearly 28% experienced a significant decrease in their discomfort. Such improvements led to noticeable boosts in overall joint function and quality of life.
Our findings affirm that hyaluronic acid injections can be a highly beneficial treatment option for individuals grappling with GH-OA. The positive responses from patients highlight the potential of this therapy to enhance not just physical function but also daily living. Eliminates arthritis pain Most Useful Review 25 people found this helpful Unbelievable! After using this for 30 days, the pain in my hands from arthritis vanished, and I regained 100% use of them. Great stuff! |
 Schiff, Glucosamine HCl, 2,000 mg, 150 Coated Tablets (1,000 mg per Tablet) | | |
Hyaluronic acid eases shoulder arthritisRetrospective evaluation of the efficacy of ultrasound-guided intra-articular hyaluronic-acid-based injections (Hyalubrix) in patients with glenohumeral osteoarthritis. We explored the impact of hyaluronic acid (HA) injections, specifically a formulation called Hyalubrix®, on patients suffering from glenohumeral osteoarthritis (GH-OA). The condition often leads to painful and disabling shoulder issues, and we aimed to find out if these injections could provide relief and improve overall quality of life.
By analyzing data collected from standard clinical practice, we focused on how patients rated their pain and shoulder function. Tools such as the Simple Shoulder Test and the Euro-Quality of Life Health Assessment allowed us to track their progress over time. We observed that more than half of the patients reported complete pain relief, while nearly 28% experienced a significant decrease in their discomfort. Such improvements led to noticeable boosts in overall joint function and quality of life.
Our findings affirm that hyaluronic acid injections can be a highly beneficial treatment option for individuals grappling with GH-OA. The positive responses from patients highlight the potential of this therapy to enhance not just physical function but also daily living. Pain-free existence Most Useful Review 1 people found this helpful Over a year ago, I began to suffer from arthritis, which led to a cortisone shot. I tried various glucosamine brands but none were effective. This product, however, is genuinely impressive, allowing me to live pain-free. I highly recommend it. My family doctor mentioned that other patients have had similar experiences, although some have said it doesn't work. |
 Osteo Bi-Flex, Joint Health, Triple Strength, 40 Coated Tablets | | |
Glucosamine and exercise enhance arthritis treatmentNutrition supplementation combined with exercise versus exercise alone in treating knee osteoarthritis: a double-blinded, randomised, placebo-controlled trial. We sought to determine whether a combination of a nutrition supplement, including glucosamine and chondroitin, along with supervised exercise, is more effective for knee osteoarthritis than exercise alone.
In a six-month double-blinded trial involving 65 participants, those who took the supplement experienced significant improvements in pain and stiffness earlier compared to those receiving a placebo.
This suggests that using glucosamine chondroitin supplementation along with exercise could be a more efficient treatment strategy for arthritis in the knee. Pain relief effective Most Useful Review 8 people found this helpful I regularly purchase this medication for my mother, aged 69, who has suffered from arthritis for over 15 years. She is very pleased with its effects, which surpass those of sulfasalazine, with fewer side effects. She takes it for two months, then has a break for two months while continuing Boswellia. After her first dose, she felt relief by the seventh day. Now, her hand joints are less inflamed and more comfortable. |
 Animal, Flex, Comprehensive Joint Care, 44 Pill Packs | | |
Glucosamine and exercise enhance arthritis treatmentNutrition supplementation combined with exercise versus exercise alone in treating knee osteoarthritis: a double-blinded, randomised, placebo-controlled trial. We sought to determine whether a combination of a nutrition supplement, including glucosamine and chondroitin, along with supervised exercise, is more effective for knee osteoarthritis than exercise alone.
In a six-month double-blinded trial involving 65 participants, those who took the supplement experienced significant improvements in pain and stiffness earlier compared to those receiving a placebo.
This suggests that using glucosamine chondroitin supplementation along with exercise could be a more efficient treatment strategy for arthritis in the knee. Joint pain relief Most Useful Review 172 people found this helpful  RECOMMEND! These are the best vitamins for my joints. After suffering from knee pain, I tried various treatments, but nothing worked until an athlete recommended Animal Flex. Following the suggested regimen, my knee pain vanished. Doctors labelled it as arthritis, yet after two years of taking this supplement, they declared I am fine now. I recommend it highly—this regimen is effective for us! |
 NOW Foods, Glucosamine & MSM, 60 Veg Capsules | | |
N-Acetyl Glucosamine reduces arthritisCollagen-induced arthritis: severity and immune response attenuation using multivalent N-acetyl glucosamine. We aimed to understand how N-acetyl glucosamine (GlcNAc), a compound known for its anti-inflammatory properties, affects the development and severity of collagen-induced arthritis (CIA). Our investigation involved applying a special multivalent GlcNAc-terminated glycoconjugate and assessing its influence through various methodologies.
The results were promising. We observed that GlcNAc treatment significantly reduced inflammation at the site of arthritis, notably decreasing the presence of immune cells that contribute to the disease. Furthermore, it appeared to hinder the activation of other immune cells, which are often involved in the production of harmful pro-inflammatory molecules.
Additionally, GlcNAc treatment not only delayed the onset of arthritis symptoms but also eased the severity of these symptoms in many cases. We found that about 18% to 31% of participants treated with GlcNAc completely avoided any arthritis symptoms. Overall, our findings support a new approach to managing arthritis by focusing on the glycobiological aspects of treatment, presenting GlcNAc as a potential therapeutic option for those suffering from this debilitating condition. Symptoms improved noted Most Useful Review Glucosamine effectively improves arthritis symptoms. |
 Doctor's Best, Glucosamine Chondroitin MSM with OptiMSM®, 240 Capsules | | |
MSM improves knee osteoarthritis symptomsEfficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. We conducted a randomized, double-blind, placebo-controlled trial exploring the effects of methylsulfonylmethane (MSM) on knee osteoarthritis pain. Fifty adults aged 40 to 76 participated, taking either MSM or a placebo for 12 weeks.
While MSM did show improvements in pain and physical function, there was no significant effect on stiffness or overall symptom scores. This means that while MSM might help with certain aspects of osteoarthritis, the overall benefits and long-term safety need more research. Knee pain relief Most Useful Review 383 people found this helpful Mum had severe knee joint pain when walking, and after a month of taking chondroprotectors, the pain disappeared. I ordered different brands, and this one from NOW seemed most effective. For added efficiency, I also got Boswellia extract, which I highly recommend. |
 NOW Foods, Vegetarian Glucosamine & MSM, 120 Veg Capsules | | |
N-Acetyl Glucosamine reduces arthritisCollagen-induced arthritis: severity and immune response attenuation using multivalent N-acetyl glucosamine. We aimed to understand how N-acetyl glucosamine (GlcNAc), a compound known for its anti-inflammatory properties, affects the development and severity of collagen-induced arthritis (CIA). Our investigation involved applying a special multivalent GlcNAc-terminated glycoconjugate and assessing its influence through various methodologies.
The results were promising. We observed that GlcNAc treatment significantly reduced inflammation at the site of arthritis, notably decreasing the presence of immune cells that contribute to the disease. Furthermore, it appeared to hinder the activation of other immune cells, which are often involved in the production of harmful pro-inflammatory molecules.
Additionally, GlcNAc treatment not only delayed the onset of arthritis symptoms but also eased the severity of these symptoms in many cases. We found that about 18% to 31% of participants treated with GlcNAc completely avoided any arthritis symptoms. Overall, our findings support a new approach to managing arthritis by focusing on the glycobiological aspects of treatment, presenting GlcNAc as a potential therapeutic option for those suffering from this debilitating condition. Confidence restored Most Useful Review 8 people found this helpful I bought this for my 66-year-old grandmother to assist with her arthritis. After taking it for a long time, she’s not afraid to handle heavy or fragile items. Her confidence when moving has returned, and it lasts for two months without side effects. If this review helps, please put YES! |
 NOW Foods, Glucosamine & Chondroitin with MSM, 180 Veg Capsules | | |
N-Acetyl Glucosamine reduces arthritisCollagen-induced arthritis: severity and immune response attenuation using multivalent N-acetyl glucosamine. We aimed to understand how N-acetyl glucosamine (GlcNAc), a compound known for its anti-inflammatory properties, affects the development and severity of collagen-induced arthritis (CIA). Our investigation involved applying a special multivalent GlcNAc-terminated glycoconjugate and assessing its influence through various methodologies.
The results were promising. We observed that GlcNAc treatment significantly reduced inflammation at the site of arthritis, notably decreasing the presence of immune cells that contribute to the disease. Furthermore, it appeared to hinder the activation of other immune cells, which are often involved in the production of harmful pro-inflammatory molecules.
Additionally, GlcNAc treatment not only delayed the onset of arthritis symptoms but also eased the severity of these symptoms in many cases. We found that about 18% to 31% of participants treated with GlcNAc completely avoided any arthritis symptoms. Overall, our findings support a new approach to managing arthritis by focusing on the glycobiological aspects of treatment, presenting GlcNAc as a potential therapeutic option for those suffering from this debilitating condition. Improved mobility Most Useful Review 9 people found this helpful My knees were suffering from arthritis for a long time. After ordering these tablets, I can now confidently say they work wonderfully! I can now walk up the stairs without difficulty. |
 NOW Foods, Folic Acid, 800 mcg, 250 Tablets | | |
Folic acid lowers inflammatory painLong-term folic acid treatment relieves chronic inflammatory pain and pain-induced anxiety by reducing MMP2 expression in rats. We investigated the effects of folic acid on chronic inflammatory pain, especially in the context of arthritis. Adult rats were used in our study, and we induced inflammatory pain by injecting a substance called complete Freund's adjuvant (CFA) into their hind paws. Through behavioral tests, we assessed pain responses by measuring how long it took for the rats to withdraw their paws from painful stimuli.
Our findings showed that the CFA injections not only caused significant pain but also increased the expression of Matrix metalloproteinase 2 (MMP2), a protein associated with inflammation. Notably, MMP2 was primarily found in nerve cells rather than glial cells, indicating its crucial role in the pain pathway.
In an exciting twist, we discovered that long-term treatment with folic acid managed to reduce the overexpression of MMP2. This led to lasting relief from chronic inflammatory pain for the rats and also alleviated pain-related anxiety. These results suggest that folic acid could be a promising therapeutic option for managing chronic inflammatory pain and anxiety in arthritis patients, allowing for better pain management in the long term. Excellent quality Most Useful Review Excellent! This supplement is ideal for anyone with immune diseases. My mother suffers from rheumatoid arthritis, and it’s of high quality. It should not be cut. |
 NOW Foods, Vitamin D-3, Max Potency, 50,000 IU, 50 Softgels | | |
Vitamin D aids rheumatoid arthritisThe role of vitamins D, B12, C, and K in modulating inflammation and disease management in rheumatoid arthritis: a comprehensive review. We explored how vitamin D plays a role in managing rheumatoid arthritis (RA), a condition that causes joint inflammation and discomfort. It's been found that many people with RA often suffer from vitamin D deficiency, which may worsen their symptoms and overall disease severity.
Our review indicates that vitamin D could help modulate immune responses and lower inflammation levels. Supplementing with vitamin D has shown potential in improving various disease activity markers, signaling that it could be a valuable addition to treatment strategies for RA.
Besides vitamin D, we also looked at other important vitamins like B12, C, and K. While vitamin D stands out for its immune benefits, B12 supports energy and neurological health, C helps with collagen production and inflammation reduction, and K contributes to bone health.
Together, these vitamins create a comprehensive approach to managing RA, emphasizing the need for further research to determine the best ways to use them effectively. Improved immunity Most Useful Review 10 people found this helpful The most crucial vitamin the body requires is vitamin D3, especially for those with arthritis or other immune disorders. It has significantly helped me as a rheumatoid arthritis sufferer by enhancing immunity and alleviating pain. I take it with a fatty meal, along with K2, to improve absorption and support calcium utilisation in the bones. The capsules are natural and of high quality, and they're reasonably priced. |
 Jarrow Formulas, Vitamin D3, 125 mcg (5,000 IU), 100 Softgels | | |
Vitamin D aids rheumatoid arthritisThe role of vitamins D, B12, C, and K in modulating inflammation and disease management in rheumatoid arthritis: a comprehensive review. We explored how vitamin D plays a role in managing rheumatoid arthritis (RA), a condition that causes joint inflammation and discomfort. It's been found that many people with RA often suffer from vitamin D deficiency, which may worsen their symptoms and overall disease severity.
Our review indicates that vitamin D could help modulate immune responses and lower inflammation levels. Supplementing with vitamin D has shown potential in improving various disease activity markers, signaling that it could be a valuable addition to treatment strategies for RA.
Besides vitamin D, we also looked at other important vitamins like B12, C, and K. While vitamin D stands out for its immune benefits, B12 supports energy and neurological health, C helps with collagen production and inflammation reduction, and K contributes to bone health.
Together, these vitamins create a comprehensive approach to managing RA, emphasizing the need for further research to determine the best ways to use them effectively. High-quality relief Most Useful Review 27 people found this helpful During this challenging year due to COVID-19, I started taking vitamin D on my rheumatologist's advice. It works well against my rheumatoid arthritis and prevents colds and viruses. Having used other brands, I find Jarrow's quality outstanding. The delivery to Kazakhstan is also good, and everything is well packaged. |
 NOW Foods, Vitamin D-3, High Potency, 5,000 IU, 120 Softgels | | |
Vitamin D aids rheumatoid arthritisThe role of vitamins D, B12, C, and K in modulating inflammation and disease management in rheumatoid arthritis: a comprehensive review. We explored how vitamin D plays a role in managing rheumatoid arthritis (RA), a condition that causes joint inflammation and discomfort. It's been found that many people with RA often suffer from vitamin D deficiency, which may worsen their symptoms and overall disease severity.
Our review indicates that vitamin D could help modulate immune responses and lower inflammation levels. Supplementing with vitamin D has shown potential in improving various disease activity markers, signaling that it could be a valuable addition to treatment strategies for RA.
Besides vitamin D, we also looked at other important vitamins like B12, C, and K. While vitamin D stands out for its immune benefits, B12 supports energy and neurological health, C helps with collagen production and inflammation reduction, and K contributes to bone health.
Together, these vitamins create a comprehensive approach to managing RA, emphasizing the need for further research to determine the best ways to use them effectively. Improved arthritis symptoms Most Useful Review 50 people found this helpful This is a superb product that has substantially improved my health and well-being. My mood has enhanced, and I no longer require medication for my arthritis. It's also been incredibly helpful during severe colds or flu. |
 NOW Foods, Cod Liver Oil, 650 mg, 250 Softgels | | |
Cod liver oil reduces arthritis symptomsEffect of cod liver oil on symptoms of rheumatoid arthritis. In a recent study, we examined the effectiveness of cod liver oil in alleviating symptoms of rheumatoid arthritis. Forty-three participants took 1 gram of cod liver oil daily for three months. The results were promising.
We observed significant reductions in morning stiffness, with an impressive 52.4% improvement. Additionally, patients reported a 42.7% decrease in painful joints and a 40% reduction in swollen joints. Pain intensity also saw a notable decline of 67.5%.
When asked about their experience, 68% of patients rated the treatment as "good" or "very good" in terms of effectiveness, and an impressive 95% found it tolerable. While some patients reported nonsevere side effects, three of those reactions might have been linked to the cod liver oil.
Overall, we find that cod liver oil could be a beneficial addition to treatment options for those suffering from rheumatoid arthritis. Game-changer for health Most Useful Review I’ve been using NOW Foods Cod Liver Oil, 650 mg, for a while, and it’s transformed my overall health. It significantly reduces inflammation, improving my joint health and alleviating arthritis-related pain. I've also experienced a decrease in anxiety and depression. The softgels are small and easy to swallow, making them a convenient choice. The quality is evident, and I've noticed benefits to my skin and hair, alongside cardiovascular support from the Vitamins A and D3. I highly recommend this product for those seeking natural health improvements. |
 Carlson, Wild Norwegian Cod Liver Oil, 16.9 fl oz (500 ml) | | |
Cod liver oil reduces arthritis symptomsEffect of cod liver oil on symptoms of rheumatoid arthritis. In a recent study, we examined the effectiveness of cod liver oil in alleviating symptoms of rheumatoid arthritis. Forty-three participants took 1 gram of cod liver oil daily for three months. The results were promising.
We observed significant reductions in morning stiffness, with an impressive 52.4% improvement. Additionally, patients reported a 42.7% decrease in painful joints and a 40% reduction in swollen joints. Pain intensity also saw a notable decline of 67.5%.
When asked about their experience, 68% of patients rated the treatment as "good" or "very good" in terms of effectiveness, and an impressive 95% found it tolerable. While some patients reported nonsevere side effects, three of those reactions might have been linked to the cod liver oil.
Overall, we find that cod liver oil could be a beneficial addition to treatment options for those suffering from rheumatoid arthritis. Pain relief Most Useful Review 2 people found this helpful I broke both my feet in my youth, resulting in significant arthritis. Since I began taking cod liver oil three months ago, it has alleviated most of the pain in my feet and improved my overall wellbeing. |
 NOW Foods, Glucosamine Sulfate, 750 mg, 240 Veg Capsules | | |
N-Acetyl Glucosamine reduces arthritisCollagen-induced arthritis: severity and immune response attenuation using multivalent N-acetyl glucosamine. We aimed to understand how N-acetyl glucosamine (GlcNAc), a compound known for its anti-inflammatory properties, affects the development and severity of collagen-induced arthritis (CIA). Our investigation involved applying a special multivalent GlcNAc-terminated glycoconjugate and assessing its influence through various methodologies.
The results were promising. We observed that GlcNAc treatment significantly reduced inflammation at the site of arthritis, notably decreasing the presence of immune cells that contribute to the disease. Furthermore, it appeared to hinder the activation of other immune cells, which are often involved in the production of harmful pro-inflammatory molecules.
Additionally, GlcNAc treatment not only delayed the onset of arthritis symptoms but also eased the severity of these symptoms in many cases. We found that about 18% to 31% of participants treated with GlcNAc completely avoided any arthritis symptoms. Overall, our findings support a new approach to managing arthritis by focusing on the glycobiological aspects of treatment, presenting GlcNAc as a potential therapeutic option for those suffering from this debilitating condition. Significant pain relief Most Useful Review 6 people found this helpful This is the first supplement that has truly improved my shoulder pain stemming from post-traumatic shoulder arthritis. Initially sceptical due to past failures with other products, I noticed a significant improvement after 3-4 weeks. I'm now almost pain-free and no longer need NSAIDs. I take 1.5g daily in the morning, increasing to 3g on more active days. Occasionally, I experience some reflux, which is manageable by taking the supplement with food. I highly recommend it to anyone suffering from arthritis, but patience is key as the effects take a few weeks to become apparent. |
 21st Century, Gelatin, 600 mg, 100 Capsules | | |
Gelatin nanoparticles show OA promiseDevelopment and functional evaluation of a hyaluronic acid coated nano-formulation with kaempferol as a novel intra-articular agent for Knee Osteoarthritis treatment. We investigated a new treatment for knee osteoarthritis using hyaluronic acid-coated gelatin nanoparticles loaded with kaempferol. This combination aimed to reduce inflammation and restore cartilage.
In our study, we found that these nanoparticles effectively improved joint health in preclinical models by lowering harmful inflammatory markers and enhancing cartilage thickness.
The results show promise for this innovative approach, indicating potential benefits in managing knee osteoarthritis symptoms. Joint relief Most Useful Review 5 people found this helpful Gelatin is crucial for healthy hair, skin, and cartilage. It contains amino acids that are well absorbed, nourishing joints and relieving arthritis pain, while also improving mobility. |
 Nordic Naturals, Omega-3, Great Lemon, 690 mg, 120 Soft Gels (345 mg per Soft Gel) | | |
Omega-3 benefits joint health in RAEffects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials. We analyzed various trials to see how omega-3 fish oil affects rheumatoid arthritis (RA). Our research included 18 randomized controlled studies with 1,018 RA patients. The results showed omega-3 supplementation significantly increased beneficial omega-3 fatty acids, like EPA and DHA, and reduced triglycerides and tender joint count.
However, it didn't lead to significant changes in some inflammation markers and overall disease activity. While there are positive outcomes regarding certain symptoms, we found no remarkable evidence for its effectiveness in reducing inflammation levels. Improved arthritic joint Most Useful Review 4 people found this helpful Excellent! There is just a slight lemony aftertaste, which is not unpleasant. I've only been taking this for a short time, so I'm not sure yet about my cholesterol. However, within a few days, I noticed a significant improvement in my arthritic finger joint, which had been troublesome due to the cold winter weather. Despite the drastic changes in temperature, my joint feels fine. Additionally, I have experienced better energy levels and digestion. I take one in the morning and one before dinner, and I'm very pleased with the results! |
 Natrol, Omega-3 Fish Oil, Lemon, 1,000 mg, 150 Softgels | | |
Omega-3 benefits joint health in RAEffects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials. We analyzed various trials to see how omega-3 fish oil affects rheumatoid arthritis (RA). Our research included 18 randomized controlled studies with 1,018 RA patients. The results showed omega-3 supplementation significantly increased beneficial omega-3 fatty acids, like EPA and DHA, and reduced triglycerides and tender joint count.
However, it didn't lead to significant changes in some inflammation markers and overall disease activity. While there are positive outcomes regarding certain symptoms, we found no remarkable evidence for its effectiveness in reducing inflammation levels. Joint health Most Useful Review 8 people found this helpful Fish oil is beneficial for the brain and boosts the immune system. It lowers blood pressure and improves joint mobility, which is vital for those suffering from arthritis. My therapist recommended it to stabilise my cholesterol. This is a high-quality product at a reasonable price. Our family takes it daily, and we notice no side effects. Highly recommended for everyone! |
 Solgar, Omega 3, EPA & DHA, Triple Strength, 950 mg, 100 Softgels | | |
Omega-3 benefits joint health in RAEffects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials. We analyzed various trials to see how omega-3 fish oil affects rheumatoid arthritis (RA). Our research included 18 randomized controlled studies with 1,018 RA patients. The results showed omega-3 supplementation significantly increased beneficial omega-3 fatty acids, like EPA and DHA, and reduced triglycerides and tender joint count.
However, it didn't lead to significant changes in some inflammation markers and overall disease activity. While there are positive outcomes regarding certain symptoms, we found no remarkable evidence for its effectiveness in reducing inflammation levels. Joint pain relief Most Useful Review 119 people found this helpful I buy this Omega-3 for my mother, who suffers from arthritis. Since she began taking it in winter, her joint and muscle pain has significantly improved. |
 Jarrow Formulas, Fish Oil, EPA-DHA Balance®, 120 Softgels | | |
Omega-3 benefits joint health in RAEffects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials. We analyzed various trials to see how omega-3 fish oil affects rheumatoid arthritis (RA). Our research included 18 randomized controlled studies with 1,018 RA patients. The results showed omega-3 supplementation significantly increased beneficial omega-3 fatty acids, like EPA and DHA, and reduced triglycerides and tender joint count.
However, it didn't lead to significant changes in some inflammation markers and overall disease activity. While there are positive outcomes regarding certain symptoms, we found no remarkable evidence for its effectiveness in reducing inflammation levels. Pain relief provided Most Useful Review This quality product, made from natural ingredients, is especially vital for older people. Omega-3 fatty acids help maintain healthy joints, relieve pain during flare-ups, and assist with rheumatoid arthritis. |
 Doctor's Best, Purified & Clear Omega 3 Fish Oil, 2,000 mg, 120 Marine Softgels (1,000 mg per Softgel) | | |
Omega-3 benefits joint health in RAEffects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials. We analyzed various trials to see how omega-3 fish oil affects rheumatoid arthritis (RA). Our research included 18 randomized controlled studies with 1,018 RA patients. The results showed omega-3 supplementation significantly increased beneficial omega-3 fatty acids, like EPA and DHA, and reduced triglycerides and tender joint count.
However, it didn't lead to significant changes in some inflammation markers and overall disease activity. While there are positive outcomes regarding certain symptoms, we found no remarkable evidence for its effectiveness in reducing inflammation levels. Alleviates pain Most Useful Review I currently take this supplement for my arthritis pain and inflammation, alongside other supplements. It has been beneficial in managing my condition. |
 NOW Foods, Ultra Omega 3-D, 600 EPA / 300 DHA, 90 Fish Softgels | | |
Omega-3 benefits joint health in RAEffects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials. We analyzed various trials to see how omega-3 fish oil affects rheumatoid arthritis (RA). Our research included 18 randomized controlled studies with 1,018 RA patients. The results showed omega-3 supplementation significantly increased beneficial omega-3 fatty acids, like EPA and DHA, and reduced triglycerides and tender joint count.
However, it didn't lead to significant changes in some inflammation markers and overall disease activity. While there are positive outcomes regarding certain symptoms, we found no remarkable evidence for its effectiveness in reducing inflammation levels. Reduced inflammation Most Useful Review This is a fantastic Omega 3 supplement that benefits my rheumatoid arthritis significantly when taken consistently. It is good value for money, with a large package for less than other brands, and helps decrease inflammation. |
 NOW Foods, Omega-3 Fish Oil, 1,000 mg, 180 EPA - 120 DHA, 100 Softgels | | |
Omega-3 benefits joint health in RAEffects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials. We analyzed various trials to see how omega-3 fish oil affects rheumatoid arthritis (RA). Our research included 18 randomized controlled studies with 1,018 RA patients. The results showed omega-3 supplementation significantly increased beneficial omega-3 fatty acids, like EPA and DHA, and reduced triglycerides and tender joint count.
However, it didn't lead to significant changes in some inflammation markers and overall disease activity. While there are positive outcomes regarding certain symptoms, we found no remarkable evidence for its effectiveness in reducing inflammation levels. Improves arthritis mobility Most Useful Review 1 people found this helpful Excellent for arthritis! I have advanced post-traumatic arthritis in my ankle, and Now Foods Omega-3 has helped eliminate pain and improve mobility. Highly recommended! |
 NOW Foods, MSM, 1,500 mg, 200 Tablets | | |
MSM improves knee osteoarthritis symptomsEfficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. We conducted a randomized, double-blind, placebo-controlled trial exploring the effects of methylsulfonylmethane (MSM) on knee osteoarthritis pain. Fifty adults aged 40 to 76 participated, taking either MSM or a placebo for 12 weeks.
While MSM did show improvements in pain and physical function, there was no significant effect on stiffness or overall symptom scores. This means that while MSM might help with certain aspects of osteoarthritis, the overall benefits and long-term safety need more research. Fingers straightened Most Useful Review 4 people found this helpful My fingers have straightened since I began taking MSM. Rheumatoid arthritis has considerable inhibiting power. |
 Doctor's Best, MSM with OptiMSM®, 3,000 mg, 360 Capsules (1,000 mg per Capsule) | | |
MSM improves knee osteoarthritis symptomsEfficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. We conducted a randomized, double-blind, placebo-controlled trial exploring the effects of methylsulfonylmethane (MSM) on knee osteoarthritis pain. Fifty adults aged 40 to 76 participated, taking either MSM or a placebo for 12 weeks.
While MSM did show improvements in pain and physical function, there was no significant effect on stiffness or overall symptom scores. This means that while MSM might help with certain aspects of osteoarthritis, the overall benefits and long-term safety need more research. Inflammation relief Most Useful Review 10 people found this helpful I bought this for my mother, who has arthritis. On the second day of taking it, she mentioned that an inflammation in her leg, which had been present for years, had subsided. |
 Jarrow Formulas, Vegan MSM, 1,000 mg, 200 Veggie Capsules | | |
MSM improves knee osteoarthritis symptomsEfficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. We conducted a randomized, double-blind, placebo-controlled trial exploring the effects of methylsulfonylmethane (MSM) on knee osteoarthritis pain. Fifty adults aged 40 to 76 participated, taking either MSM or a placebo for 12 weeks.
While MSM did show improvements in pain and physical function, there was no significant effect on stiffness or overall symptom scores. This means that while MSM might help with certain aspects of osteoarthritis, the overall benefits and long-term safety need more research. Joint pain decrease Most Useful Review 5 people found this helpful MSM helps with my friend’s psoriatic arthritis. She suffers unbearable pain, and long-term painkiller use is harmful to her liver. After reading reviews on IHerb, I ordered these tablets, finding them convenient. Improvements were evident within days, as joint pain significantly decreased. She takes two tablets in the morning and evening. |
 NOW Foods, MSM, Methylsulfonylmethane, 1,000 mg, 120 Veg Capsules | | |
MSM improves knee osteoarthritis symptomsEfficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. We conducted a randomized, double-blind, placebo-controlled trial exploring the effects of methylsulfonylmethane (MSM) on knee osteoarthritis pain. Fifty adults aged 40 to 76 participated, taking either MSM or a placebo for 12 weeks.
While MSM did show improvements in pain and physical function, there was no significant effect on stiffness or overall symptom scores. This means that while MSM might help with certain aspects of osteoarthritis, the overall benefits and long-term safety need more research. Reduces joint pain Most Useful Review 61 people found this helpful Very good additive! MSM is an organic sulphur compound with anti-inflammatory effects. I purchased it for my mother, who suffers from arthritis, and she has experienced some relief in her joint pain and sinus issues. I also tried it for my allergies, and it has significantly reduced my morning cough and improved my breathing. I even found relief from severe bloating that previous medications couldn't alleviate. |
 NOW Foods, UC-II® Joint Health with Undenatured Type II Collagen, 120 Capsules | | |
Collagen may alleviate knee OA symptomsEffect of collagen supplementation on knee osteoarthritis: an updated systematic review and meta-analysis of randomised controlled trials. We explored the effects of collagen-based supplements on knee osteoarthritis (OA) by analyzing data from 11 randomized controlled trials, involving 870 participants.
The findings demonstrated that those taking collagen experienced significant improvements in both function and pain scores compared to a placebo group.
Specifically, results indicated an average reduction in pain and improved functionality, suggesting that collagen supplementation can be beneficial for managing OA symptoms. Relief from joints Most Useful Review 3 people found this helpful I have rheumatoid arthritis, and this collagen is my saviour. After a month, my joints felt relief, and I strongly recommend it! |
 NOW Foods, BioCell Collagen®, Hydrolyzed Type II, 120 Veg Capsules | | |
Hyaluronic acid eases shoulder arthritisRetrospective evaluation of the efficacy of ultrasound-guided intra-articular hyaluronic-acid-based injections (Hyalubrix) in patients with glenohumeral osteoarthritis. We explored the impact of hyaluronic acid (HA) injections, specifically a formulation called Hyalubrix®, on patients suffering from glenohumeral osteoarthritis (GH-OA). The condition often leads to painful and disabling shoulder issues, and we aimed to find out if these injections could provide relief and improve overall quality of life.
By analyzing data collected from standard clinical practice, we focused on how patients rated their pain and shoulder function. Tools such as the Simple Shoulder Test and the Euro-Quality of Life Health Assessment allowed us to track their progress over time. We observed that more than half of the patients reported complete pain relief, while nearly 28% experienced a significant decrease in their discomfort. Such improvements led to noticeable boosts in overall joint function and quality of life.
Our findings affirm that hyaluronic acid injections can be a highly beneficial treatment option for individuals grappling with GH-OA. The positive responses from patients highlight the potential of this therapy to enhance not just physical function but also daily living. Wonderful relief Most Useful Review This is good collagen. I purchased it for my mother who has arthritis, and it has helped her wonderfully with decreased joint pain. |
 Doctor's Best, High Potency Bromelain, 500 mg, 90 Veggie Caps | | |
Bromelain shows promise against arthritisExploration of bromelain laden nanostructured lipid carriers: An oral platform for bromelain delivery in rheumatoid arthritis management. We explored a new way to deliver bromelain, a natural enzyme, using nanostructured lipid carriers (Br-NCs).
Our research aimed to improve bromelain's stability and effectiveness in managing rheumatoid arthritis.
The study showed that Br-NCs significantly reduced joint swelling and stiffness in preclinical trials.
These carriers also enhanced bromelain's shelf-life and showed promise as a novel treatment option for arthritis. Positive effects noted Most Useful Review Arthritis really works. |
 NOW Foods, Double Strength DHA-500 Fish Oil, 180 Softgels | | |
Eicosapentaenoic acid aids arthritisEffects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials. We explored the effects of eicosapentaenoic acid (EPA), a key component of omega-3 fatty acids, on patients with rheumatoid arthritis (RA). This analysis gathered data from eighteen randomized controlled trials involving over a thousand RA patients, ensuring a comprehensive look at its impact.
Our findings revealed that EPA supplementation significantly increased levels of both eicosapentaenoic acid and docosahexaenoic acid (DHA). Additionally, we noted a reduction in the omega-6 to omega-3 fatty acid ratio, which is beneficial for overall health.
Moreover, we observed that EPA led to a decrease in triglyceride levels and tender joint counts among RA patients. However, while there were slight decreases in markers of inflammation, such as erythrocyte sedimentation rate and C-reactive protein, these changes were not statistically significant.
Overall, our analysis supports the idea that EPA has positive effects on lipid profiles and joint tenderness for those with RA, although not all inflammatory markers showed significant improvement. Arthritis improvement Most Useful Review 1 people found this helpful I highly recommend this Omega 3 package. It’s excellent for arthritis and heart health, with great taste and quality. It lowers cholesterol, improves lifespan, and has beneficial ingredients. |
 Nature's Way, Black Elderberry, 1,150 mg, 100 Vegan Capsules (575 mg per Capsule) | | |
Elderberry shows promise for arthritisEfficacy and short-term safety of topical Dwarf Elder (Sambucus ebulus L.) versus diclofenac for knee osteoarthritis: A randomized, double-blind, active-controlled trial. We explored the effectiveness of Dwarf Elder, or Sambucus ebulus, in treating knee osteoarthritis (OA) by conducting a randomized, double-blind clinical trial. In this study, we compared topical S. ebulus gel to a 1% diclofenac gel, known for its anti-inflammatory properties. Seventy-nine patients participated, applying the treatment three times a day for four weeks.
Throughout the trial, we measured changes in knee pain using a visual analogue scale and assessed functional improvements with the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire.
Our findings suggest that topical S. ebulus gel might effectively ease knee OA symptoms. However, we noted that further research with larger groups is essential to confirm the long-term efficacy and safety of this natural remedy. Overall, while the initial results are promising, more extensive trials will provide a clearer perspective on the true potential of elderberry in managing knee osteoarthritis. Immunity boost Most Useful Review 10 people found this helpful Elderberry helps improve immunity and is beneficial for colds and arthritis. I take 2 capsules with vitamin C and D, and echinacea to recover quickly. During a mild illness, elderberry proved invaluable. I believe it’s essential to have elderberry at home as a remedy for colds. I highly recommend it! |
 Solgar, Evening Primrose Oil, 1,300 mg, 60 Softgels | | |
EPO shows symptom relief potentialEffects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: a double blind placebo controlled study. This study explored whether evening primrose oil (EPO) could replace non-steroidal anti-inflammatory drugs (NSAIDs) for people with rheumatoid arthritis (RA).
Over 12 months, we noticed that patients taking EPO showed notable subjective improvements and were able to reduce their NSAID intake.
However, a follow-up after three months of placebo indicated that while they felt better initially, their symptoms returned.
Importantly, EPO didn't change underlying disease progression, meaning it may not be a cure but can support symptom relief. Anti-inflammatory benefits Most Useful Review 1 people found this helpful This oil effectively reduces PMS and menopause pain and is useful for chronic skin ailments like eczema and acne. Evening Primrose Oil serves as an anti-inflammatory agent, proving advantageous for arthritis. I wholeheartedly recommend this brand. |
 Jarrow Formulas, Evening Primrose, 1,300 mg, 60 Softgels | | |
EPO shows symptom relief potentialEffects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: a double blind placebo controlled study. This study explored whether evening primrose oil (EPO) could replace non-steroidal anti-inflammatory drugs (NSAIDs) for people with rheumatoid arthritis (RA).
Over 12 months, we noticed that patients taking EPO showed notable subjective improvements and were able to reduce their NSAID intake.
However, a follow-up after three months of placebo indicated that while they felt better initially, their symptoms returned.
Importantly, EPO didn't change underlying disease progression, meaning it may not be a cure but can support symptom relief. Manages arthritis symptoms Most Useful Review 5 people found this helpful Primula oil regulates hormones and helps with various ailments, including arthritis and menstrual disorders. It has a positive effect on high blood pressure and is effective against eczema and diabetes. I took it to restore my cycle and was pleased with the results. My skin did become quite oily, so I will try another course in winter. |
 NOW Foods, Super Primrose, 1,300 mg, 120 Softgels | | |
EPO shows symptom relief potentialEffects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: a double blind placebo controlled study. This study explored whether evening primrose oil (EPO) could replace non-steroidal anti-inflammatory drugs (NSAIDs) for people with rheumatoid arthritis (RA).
Over 12 months, we noticed that patients taking EPO showed notable subjective improvements and were able to reduce their NSAID intake.
However, a follow-up after three months of placebo indicated that while they felt better initially, their symptoms returned.
Importantly, EPO didn't change underlying disease progression, meaning it may not be a cure but can support symptom relief. Improves arthritis symptoms Most Useful Review 54 people found this helpful This oil is fantastic! It’s rich in gamma-linolenic acid and helps alleviate menstrual and menopausal symptoms, skin issues, arthritis, and improves fertility. I've noticed an improvement in my skin's elasticity and moisture. For best results, it's advised to take the capsules for 12 weeks. Stay healthy! |
 Sports Research, Omega-3 Fish Oil, Triple Strength , 30 Softgels | | |
Eicosapentaenoic acid aids arthritisEffects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials. We explored the effects of eicosapentaenoic acid (EPA), a key component of omega-3 fatty acids, on patients with rheumatoid arthritis (RA). This analysis gathered data from eighteen randomized controlled trials involving over a thousand RA patients, ensuring a comprehensive look at its impact.
Our findings revealed that EPA supplementation significantly increased levels of both eicosapentaenoic acid and docosahexaenoic acid (DHA). Additionally, we noted a reduction in the omega-6 to omega-3 fatty acid ratio, which is beneficial for overall health.
Moreover, we observed that EPA led to a decrease in triglyceride levels and tender joint counts among RA patients. However, while there were slight decreases in markers of inflammation, such as erythrocyte sedimentation rate and C-reactive protein, these changes were not statistically significant.
Overall, our analysis supports the idea that EPA has positive effects on lipid profiles and joint tenderness for those with RA, although not all inflammatory markers showed significant improvement. Pain relief Most Useful Review 115 people found this helpful Despite the high price, I find this omega-3 to be the best available in terms of quality and ingredients. It effectively alleviates my arthritis pain when combined with vitamin D and curcumin, and even enhances my focus, which I had been losing due to my condition. |
 Jarrow Formulas, N-A-G, 700 mg, 120 Veggie Capsules | | |
Potential OA treatment advancementsNovel phosphoramidate prodrugs of N-acetyl-(D)-glucosamine with antidegenerative activity on bovine and human cartilage explants. We explored the potential of N-acetyl-(D)-glucosamine, a compound often used as a dietary supplement for osteoarthritis (OA), to provide effective relief from this chronic joint condition. Our research focused on a series of newly developed prodrugs, specifically targeting ways to enhance the compound's absorption and effectiveness within the body.
We found that some modified versions of N-acetyl-(D)-glucosamine, known as O-3 and O-4 phosphate prodrugs, demonstrated significant chondroprotective effects in vitro. In simple terms, this means they helped protect and support cartilage health, which is vital for those suffering from OA. Notably, the prodrugs that included a specific amino acid called (L)-proline were particularly effective, even outperforming earlier versions.
Overall, our findings suggest that these novel compounds hold promise as new leads in the search for more effective treatments for osteoarthritis. They signify a positive step toward improving the management of this painful and degenerative joint disease. Pain relief Most Useful Review 15 people found this helpful I discovered this supplement by chance on the iHerb website. I suffer from various food allergies, digestive issues, and arthritis. After a difficult weekend with an upset stomach and aching arthritis, I began taking this supplement. My stomach felt soothed immediately, and my arthritis pain vanished. I can hardly believe the improvement in my arthritis and digestion. I have no plans to stop taking this supplement. |
 NOW Foods, Cat's Claw, 500 mg, 250 Veg Capsules | | |
Cat's claw benefits knee arthritisEfficacy and safety of freeze-dried cat's claw in osteoarthritis of the knee: mechanisms of action of the species Uncaria guianensis. We conducted a study to determine whether cat's claw, a medicinal plant from the Amazon, could effectively treat osteoarthritis of the knee. With 45 participants, we divided them into two groups—30 received freeze-dried Uncaria guianensis, while 15 were given a placebo. Over four weeks, we monitored their health through various assessments, including pain levels and any potential side effects.
Our findings indicated that cat's claw showed no harmful effects on participants' blood or liver function when compared to the placebo. Importantly, those taking cat's claw reported significant reductions in pain during activity and improvements in assessment scores within the first week. However, we did note that pain relief during rest or at night, as well as changes in knee circumference, were not significantly impacted in this short time frame.
In our lab tests, both U. guianensis and U. tomentosa demonstrated equivalent abilities to neutralize harmful free radicals and inhibit the production of TNFalpha, an inflammatory marker. Although cat's claw did reduce the release of another inflammatory substance, PGE2, this effect required higher concentrations than needed for TNFalpha inhibition. Overall, our study suggests that cat's claw could be an effective natural treatment option for managing knee osteoarthritis symptoms. Effective for inflammation Most Useful Review 2 people found this helpful I have used cat's claw for years to combat inflammation resulting from arthritis. It works well for me. This is my first purchase of this brand: the price was reasonable and delivery was prompt. |
 NOW Foods, Flax Oil, 1,000 mg, 100 Softgels | | |
Effective arthritis management Most Useful Review 1 people found this helpful I’ve used various brands of flax oil over the years, but Now Flax Oil veggie softgels are my favourite. They're convenient and come in a 1,000 mg size, which is perfect for managing my arthritis. I will never voluntarily stop using this supplement or brand. Beneficial for health Most Useful Review Flaxseed oil is rich in Omega 3, which I use for my heart, arthritis, and cholesterol. I've experienced great benefits, even for memory, hair, and skin. The product is vegetarian, high quality, and reasonably priced. I highly recommend flax oil for those with arthritis. |
 Solgar, Omega 3-6-9, 1,300 mg, 120 Softgels | | |
Effective for arthritis Most Useful Review 2 people found this helpful Excellent. I am very pleased. After six months of breastfeeding, my joints began to ache, particularly my left thumb, which virtually ceased to function. I felt chills and discomfort similar to ARVI. I began taking omega combined with collagen, and within three days, I noticed an improvement. A month later, I regained movement in my finger. I regret not using these supplements from the beginning, as I believe I’ve developed arthritis. I am satisfied; it did not affect my baby, and I experienced no allergic reactions. The packaging was intact, the fishy smell was evident, and the capsules were not stuck together. All is perfect. High-quality supplement Most Useful Review Frankly, this is one of the best types of Omega available. The product effectively supports hair, heart, and arthritis health. I am very satisfied with the quality and will certainly order again. |
 Solgar, Skin, Nails & Hair, Advanced MSM Formula, 60 Tablets | | |
Significant hair improvement Most Useful Review 6 people found this helpful I purchased this supplement in despair due to my rheumatoid arthritis and hair loss, both undesired effects of this disease. To my amazement, after just 3-4 days of taking 2 capsules a day, I noticed a significant reduction in hair fall, which ceased completely after 10 days. My joint condition also improved significantly, despite not taking other joint supplements like MSM, hyaluronic acid, or curcumin. The inclusion of L-lysine (as HCl) in "Skin, Nails and Hair" was likely beneficial. After two months, my hair regained its shine, my nails no longer flaked, and my joints felt much better. Effective arthritis management Most Useful Review The MSM formula combined with Collagen Type 2 is excellent for managing arthritis. |
 NOW Foods, Super Omega 3-6-9, 1,200 mg, 90 Softgels | | |
Eases arthritis pain Most Useful Review Now Foods' "Super Omega 3-6-9" is a valuable product due to its high content of unsaturated fatty acids. Cold-pressed flaxseed oils retain essential nutrients and reduce inflammation, which helps alleviate pain associated with arthritis and lowers cholesterol levels. Helps arthritis significantly Most Useful Review 3 people found this helpful Fast delivery and excellent quality. This supplement is a remedy for everything! It helps regulate my female cycle, improves skin, and reduces hair loss. I’ve noticed that it alleviates pain during arthritis flare-ups, fights bone mass loss, and eases inflammation. |
 Nature's Way, Mega-Zyme, Systemic Enzymes, 100 Tablets | | |
Reduced pain significantly Most Useful Review 10 people found this helpful These proteolytic enzymes taken on an empty stomach are effective for managing autoimmune manifestations, particularly arthritis. I've used them for a month and noticed improved bowel movements, reduced swelling, and enhanced overall wellbeing. I no longer experience headaches, and my back and legs don't hurt after exertion. While I believe this treatment should be part of a comprehensive approach, these enzymes are crucial to my progress. Pain relief noticed Most Useful Review 2 people found this helpful This treatment works flawlessly for my rheumatoid arthritis, alleviating pain and muscle spasms in my joints. |
 Solgar, No. 7, Advanced Joint Support Complex, 90 Vegetable Capsules | | |
Effective pain relief Most Useful Review 129 people found this helpful Good day! I tried a plant extract supplement instead of my usual arthritis prevention protocol. I experienced positive results; after two weeks, the pain in my shoulder disappeared and didn't return for six months. I highly recommend this supplement based on my experience! Supports joint health Most Useful Review 94 people found this helpful Complex N 7 is effective for bursitis, helping alleviate pain and swelling due to arthritis. After using this product, my discomfort and swelling improved significantly, allowing greater mobility in my joints. I will continue taking it regularly. |
 NOW Foods, Mega D-3 & MK-7, 5,000 IU / 180 mcg, 60 Capsules | | |
Remarkable effectiveness Most Useful Review Excellent product! It has helped my rheumatoid arthritis pain by 99%. Soreness eased Most Useful Review Taking the added mk-7 has improved the vitamin D3 levels, effectively reducing my arthritis stiffness and pain. It has been beneficial for both my husband and me. |
 NOW Foods, Sunflower Lecithin, 1,200 mg, 200 Softgels | | |
Calms nervous system Most Useful Review I want to share my experience with Lecithin from sunflower. It’s a remarkable drug that effectively promotes bile flow. My husband takes it alongside other medications for rheumatic arthritis. It calms the nervous system without needing sedatives. Constipation resolves, and clarity of thought improves. It really is a godsend! Condition has improved Most Useful Review I take this lecithin to normalise bile flow as I have a gallbladder issue and follow an autoimmune protocol due to rheumatoid arthritis. My pain on the right side and hypochondrium barely bothers me anymore. I also take medications to help my liver function since I'm on cytostatics. My condition has greatly improved! |
 Doctor's Best, NAC Detox Regulators with Seleno Excell®, 60 Veggie Caps | | |
Combats arthritis inflammation Most Useful Review 2 people found this helpful Acetylcysteine improves kidney function and boosts immunity. Its strong anti-inflammatory properties make it effective against arthritis. It also acts as an antidote for paracetamol poisoning and can aid in various poisonings, including aldehydes and phenols found in polluted environments. Supports overall health Most Useful Review 1 people found this helpful NAC is a wonderful aid for antioxidant production! I've researched ways to heal from rheumatoid arthritis and chronic lung inflammation. This has really reduced inflammation, alleviated joint pain, and improved my breathing. I’m so grateful to have found this product. |
 NOW Foods, Rutin, 450 mg, 100 Veg Capsules | | |
Relieves leg pain Most Useful Review Great product at an excellent price! I use it to strengthen blood vessels and improve circulation while relieving arthritis symptoms. After using it for five days, my legs feel much better. Supports inflammation reduction Most Useful Review Vitamin P is utilised in alternative medicine to enhance vitamin C effects, support circulation, act as an antioxidant, and treat arthritis and other inflammatory conditions. |
 Herb Pharm, Arnica Oil, 1 fl oz (30 ml) | | |
Effective for pain Most Useful Review Arnica Oil is very effective for arthritis pain and works well. I've also used it for bruises and other aches. Relieves joint pain Most Useful Review I find that it better relieves the arthritis in my knees and hands, making me feel good overall. |
 Life Extension, Super Selenium Complex & Vitamin E, 200 mcg, 100 Vegetarian Capsules | | |
Relieves joint pain Most Useful Review Selenium and E are minerals and trace elements that can relieve joint pain in rheumatoid arthritis. Improves joint mobility Most Useful Review I asked for selenium due to its numerous benefits. It aids in improving joint mobility and is recommended for rheumatoid arthritis. I'm optimistic it will help me, and I recommend it. |
 NOW Foods, Selenium, 100 mcg, 100 Tablets | | |
Relieves arthritis symptoms Most Useful Review 3 people found this helpful I am very pleased with this product. The quality is excellent, and it contains natural ingredients suitable for everyone. It compensates for the benefits of fish due to its omega content, regulates cholesterol levels, and notably relieves arthritis symptoms. The packaging is impressive, and the formula enhances skin and heart health, as well as providing essential minerals. It's a wonderful supplement that I would gladly use again. Supports arthritis treatment Most Useful Review Selenium is utilised throughout the body, playing a significant role in cancer defence and immune response against various viruses. It's also helpful for cardiovascular health and in reducing the risk of sudden coronary death. Importantly, it helps manage rheumatoid arthritis due to its anti-inflammatory properties. Selenium is involved in thyroid hormone production and improves insulin use in diabetes. Additionally, it promotes gastrointestinal health, making it beneficial in many areas of treatment and well-being. |
 NOW Foods, Certified Organic Spirulina, Double Strength, 1,000 mg, 120 Tablets | | |
Effective for arthritis Most Useful Review I'm optimistic about its effect on arthritis. I take it because it is beneficial for knee arthritis, and I consume fatty meat along with it after meals. Healing action noted Most Useful Review 1 people found this helpful Provides a beneficial effect on the gastrointestinal tract, functioning as a prebiotic and promoting healthy microflora. It assists in combating allergies and eases symptoms of allergic rhinitis by reducing cellular reactions to allergens. This product offers antioxidant protection through compounds that effectively neutralise oxidative damage from free radicals. Additionally, it aids in lowering cholesterol and blood pressure, alongside controlling diabetes. Its healing properties also extend to arthritis. |
 NOW Foods, Stinging Nettle Root Extract, 250 mg, 90 Veg Capsules | | |
Works effectively Most Useful Review 9 people found this helpful Now Foods Stinging Nettle Root Extract, 250 mg, works really well for arthritis. Significant improvement Most Useful Review 1 people found this helpful I am Mommy Rebekah, aged 62. Last year, I suffered from degenerative arthritis in my right finger, causing stiffness and discomfort each morning. Since taking this product, I have experienced significant improvement. |
 NOW Foods, Essential Oils, Peppermint, 4 fl oz (118 ml) | | |
Effective for knee pain Most Useful Review I use it to massage my knee affected by arthritis, and it is very effective. Calms arthritis pain Most Useful Review Love the scent. I use it in my humidifier to fragrance my home. Peppermint has a relaxing quality that soothes the senses. I appreciate the benefits it provides when added to lotion to ease my arthritis. Great price too. |
 NOW Foods, Essential Oils, Ginger, 1 fl oz (30 ml) | | |
Significant pain reduction Most Useful Review I had severe pain in my hands due to arthritis, feeling as if my fingers would break. After applying this ginger oil nightly before bed, I began to feel a difference within a week. After a month, most of the pain had vanished. I keep it by my bedside. Regular pain relief Most Useful Review I use it regularly as it's effective for relieving arthritis pain. |
 Doctor's Best, Alpha-Lipoic Acid 600, 600 mg, 180 Veggie Caps | | |
Pain relief noted Most Useful Review 6 people found this helpful I started taking this supplement about two months ago to assist with arthritis in my fingers and sciatica pain. I can't pinpoint when the pain subsided; one day I just realised, “wow, I haven’t had pain in a while!” ALA, combined with specific exercises for my sciatica, has provided me with considerable relief. The arthritis in my fingers is nearly gone. Game changer experience Most Useful Review 2 people found this helpful This is my third bottle of Doctor's Best Alpha-Lipoic Acid. It has been transformative for managing my arthritis, especially in my fingers (being vegan has likely helped too). I highly recommend it for anyone with mild arthritis. |
 Green Foods, Green Magma®, Barley Grass Juice Powder, 10.6 oz (300 g) | | |
Extended arthritis relief Most Useful Review 1 people found this helpful Green Magma is a vital part of my daily routine. My grandmother claims it reversed her rheumatoid arthritis when she began taking two doses a day 30 years ago, with symptoms eventually fading. Although the arthritis resurfaced after 30 years, if she's right, it granted her those extra years. I started using it after learning from her and another healthy family member. I consume it every morning before my workout, and I believe it contributes to my overall energy and wellness throughout the day. We certainly need more greens in our diet! I appreciate that Green Magma is derived from a single plant, unlike some brands that mix many herbs, making digestion easier and tastier. Improved arthritis control Most Useful Review I can't go a day without Green Magma. It energises me and helps manage my rheumatoid arthritis. I truly notice the difference when I skip it. |
 NOW Foods, Alfalfa, 650 mg, 500 Tablets | | |
Wonders for arthritis Most Useful Review 1 people found this helpful I have been taking alfalfa for over 30 years, and it has done wonders for my arthritis. Helps with arthritis Most Useful Review 1 people found this helpful I purchased this for my 90-year-old mother-in-law, who knits all the time, and it assists her with arthritis in her hands. She swears by it. |
 ChildLife Essentials, Essentials, Echinacea, Natural Orange, 1 fl oz (30 ml) | | |
Inflammation reduction Most Useful Review Preparations containing echinacea help reduce systemic inflammation in arthritis. Its anti-inflammatory and immunomodulatory effects are beneficial against respiratory diseases, including asthma. Anti-inflammatory benefits Most Useful Review Echinacea preparations reduce systemic inflammation in arthritis, while its anti-inflammatory properties aid in combating respiratory conditions. |
 Citrucel, Methylcellulose Fiber Therapy for Irregularity, 180 Fiber Caplets | | |
Pain relief achieved Most Useful Review 533 people found this helpful It helps with arthritis! Animal Flex is a substantial can containing 44 sachets, each with 8 tablets and capsules. I ordered it for my mother, aged 64, who suffers from knee, lower back, and shoulder pain. After trying various pills and hospital treatments, nothing worked until we tried Animal Flex. Initially sceptical, my mother soon found relief after a few weeks, experiencing less pain and improved sleep without the need for painkillers. Though after some time, we did have to resume pain medication, this product shows success in severe cases, especially for arthritis sufferers. Effective anti-inflammatory Most Useful Review 246 people found this helpful I chose to buy this specific phytosomal curcumin, Meriva, which is a patented formula combined with lecithin phospholipids. This formula addresses curcumin's main issue – its bioavailability – and ensures a consistent release. Studies have shown Meriva to be 29 times more digestible than regular curcumin powder. It significantly benefits arthritis sufferers, particularly in managing rheumatoid arthritis and osteoarthritis. I hope this review proves useful; I am thankful for others' feedback as it has guided my choices. |
 NOW Foods, Resveratrol, 200 mg, 120 Veg Capsules | | |
Reduces arthritis symptoms Most Useful Review 7 people found this helpful Resveratrol is a powerful natural antioxidant that supports heart health and combats conditions like coronary heart disease and arteriosclerosis. It also lowers cholesterol, alleviates arthritis, and has anti-aging properties for the skin. Now Foods offers convenient 200 mg capsules, which can be taken throughout the day for those requiring higher doses. I highly recommend this product! Supports arthritis treatment Most Useful Review 3 people found this helpful This powerful antioxidant from grape seeds is suitable for those favouring natural remedies. Resveratrol may lower blood pressure, which is pertinent for those with low pressure. Weight loss requires a calorie deficit, but this supplement also slows cognitive decline and could enhance insulin sensitivity while easing arthritis pain. Thus, older individuals may benefit significantly. |
 NOW Foods, Solutions, Glucosamine, MSM & Arnica, Liposome Lotion, 8 fl oz (237 ml) | | |
Effective pain relief Most Useful Review 11 people found this helpful I find this product very effective for my arthritis. I struggled to sleep due to pain, but this cream alleviates it enough for a good night's rest. Although it doesn't last long, the relief it provides allows me to feel better until morning. While the smell isn't pleasant, the benefits outweigh this, and I will continue using it. Magical results Most Useful Review 10 people found this helpful This cream worked wonders for my rheumatoid arthritis. After using it only twice, I experienced remarkable relief in my swollen elbows. I’m incredibly grateful for this product and its effectiveness. |