Zinc
9
Zinc oxide mitigates diarrhea impacts
Zinc Oxide Administration Relieves the Diarrhea of ETEC K88-Infected Piglets by Reducing Ileal Apoptosis and Maintaining Gut Microbial Balance.
Most Relevant Research
We explored how zinc oxide (ZnO), often used as a feed additive, affects diarrhea and gut health in piglets infected with the ETEC K88 strain. Through careful observation, we found that piglets suffering from this infection exhibited significantly increased fecal scores compared to those not affected. The ETEC K88 strain harms the small intestine, leading to a loss of villus height and a decrease in important antioxidant activities.
Our findings revealed that ZnO administration counteracts these negative effects effectively. It not only improved the overall health of the intestine but also enhanced its ability to combat oxidative stress. We also observed a balanced restoration of gut microbiota, as ZnO helped normalize the populations of certain beneficial bacteria altered by the infection.
In summary, our study indicates that ZnO can play a vital role in easing diarrhea in piglets infected with ETEC K88 by reducing intestinal damage, supporting antioxidative defenses, and restoring healthy gut flora.
Our findings revealed that ZnO administration counteracts these negative effects effectively. It not only improved the overall health of the intestine but also enhanced its ability to combat oxidative stress. We also observed a balanced restoration of gut microbiota, as ZnO helped normalize the populations of certain beneficial bacteria altered by the infection.
In summary, our study indicates that ZnO can play a vital role in easing diarrhea in piglets infected with ETEC K88 by reducing intestinal damage, supporting antioxidative defenses, and restoring healthy gut flora.
8.3
Caused diarrhoea
Most Useful Review
I bought this for folliculitis after stopping antibiotics, hoping to boost my immunity. The tablets are small and easy to take. After a week and taking two daily, I experienced diarrhoea, so now I take one at a time. No other side effects noticed.
Vitamins
8
Vitamin D alleviates rotavirus diarrhea
1α,25-hydroxyvitamin D alleviated rotavirus infection induced ferroptosis in IPEC-J2 cells by regulating the ATF3-SLC7A11-GPX4 axis.
Most Relevant Research
We observed that rotavirus infection predominantly affects mature intestinal cells, leading to severe digestive issues, including diarrhea. This research delved into how 1α,25-hydroxyvitamin D (commonly known as vitamin D) might be influential in mitigating these detrimental effects. Various experiments were conducted with IPEC-J2 cells to analyze the impact of rotavirus on cell death and inflammation.
Our findings revealed that rotavirus not only led to cell death but also induced a specific form of cell death called ferroptosis. This situation was characterized by increased reactive oxygen species and decreased mitochondrial activity, factors that can worsen inflammation and damage gut cells. Interestingly, treatment with vitamin D significantly reduced these harmful effects. It appeared to operate through a specific pathway involving key proteins that protect cells from oxidative stress.
In summary, our study suggests that vitamin D has a protective role and inhibits rotavirus-induced cell damage and ferroptosis. By regulating certain cellular pathways, vitamin D may alleviate the intestinal distress caused by rotavirus, offering a potential therapeutic avenue against diarrhea linked to this virus. Overall, this research supports the consideration of vitamin D as a beneficial treatment in managing rotavirus infections and their associated symptoms.
Our findings revealed that rotavirus not only led to cell death but also induced a specific form of cell death called ferroptosis. This situation was characterized by increased reactive oxygen species and decreased mitochondrial activity, factors that can worsen inflammation and damage gut cells. Interestingly, treatment with vitamin D significantly reduced these harmful effects. It appeared to operate through a specific pathway involving key proteins that protect cells from oxidative stress.
In summary, our study suggests that vitamin D has a protective role and inhibits rotavirus-induced cell damage and ferroptosis. By regulating certain cellular pathways, vitamin D may alleviate the intestinal distress caused by rotavirus, offering a potential therapeutic avenue against diarrhea linked to this virus. Overall, this research supports the consideration of vitamin D as a beneficial treatment in managing rotavirus infections and their associated symptoms.
9.5
Magic for tummy troubles
Most Useful Review
I find this product incredibly useful for my children who suffer from stomach ache, diarrhoea, or constipation—it truly works like magic.
9.5
Eliminated diarrhoea
Most Useful Review
Super-agent! If not for these drops, we would likely still suffer from Staphylococcus aureus in the intestine. After 1.5 years of disappointing treatments, I discovered that a strong immune system is vital. I ordered this Echinacea without alcohol or harmful substances, sufficient for two 14-day courses. After just a week, the diarrhoea vanished completely. It’s straightforward and effective. Now, I always have it on hand for my child's vulnerable phase at nursery. I highly recommend it for children with fragile immune systems.
9.5
Effective for diarrhoea
Most Useful Review
I highly recommend psyllium for weight loss and gastrointestinal issues. It's a natural adsorbent that cleanses the intestines. The effects were noticeable soon after starting; my bowel movements became regular, and it lessened my appetite. It has also improved my skin condition, and I've seen a decrease in weight. I suggest including psyllium in your diet!
Slippery Elm
9.5
Relieves diarrhoea
Most Useful Review
I use slippery elm for gastrointestinal issues and heartburn. It's effective for both diarrhoea and constipation by forming a soothing gel. It helped me during poisoning episodes and relieved colic pain.
9.5
Stops diarrhoea
Most Useful Review
I discovered slippery elm for my irritable bowel syndrome. It quickly stopped my diarrhoea. I take two capsules with each meal, and while the taste is odd, it does the job effectively.
Probiotics
8
Probiotics reduce diarrhea in piglets
Supplementation with probiotics co-cultivation improves the reproductive performance in a sow-piglet model by mother-infant microbiota transmission and placental mTOR signaling.
Most Relevant Research
We investigated how maternal supplementation with a probiotic blend during pregnancy affects offspring outcomes. By using 40 pregnant sows, we divided them into two groups—one received a regular diet, while the other was supplemented with Lactobacillus acidophilus and Bacillus subtilis.
Results showed that the group receiving the probiotic experienced significantly lower rates of diarrhea and improved birth and weaning weights. Additionally, the supplementation improved colostrum quality and the beneficial bacteria transferred to the piglets, which supports their overall health and development. The study highlights the positive impact of maternal nutrition on offspring health.
Results showed that the group receiving the probiotic experienced significantly lower rates of diarrhea and improved birth and weaning weights. Additionally, the supplementation improved colostrum quality and the beneficial bacteria transferred to the piglets, which supports their overall health and development. The study highlights the positive impact of maternal nutrition on offspring health.
9.5
Quickly alleviates diarrhea
Most Useful Review
Boulardy saccharomycetes are a must-have for any home. After my father suffered from severe diarrhea owing to antibiotic treatment, I persuaded the doctor to prescribe this probiotic. Remarkably, his condition improved to a normal stool within a day. My kitten also benefited from these capsules, and it resolved her digestive issues quickly. Even during my pregnancy, these helped alleviate my nighttime heartburn. Boulardi is invaluable for everyone, and I recommend it for effective relief from diarrhea and digestive issues.
Potassium
8.3
Muscle cramps reduced
Most Useful Review
An elderly relative experienced muscle cramps and other issues after prolonged diarrhoea. The doctor recommended potassium for fluid balance. They don’t consume potassium-rich foods due to a low-carb diet. The small capsules are easy to swallow, and after following the therapist’s advice, muscle weakness decreased.
8.8
Potassium supplements needed
Most Useful Review
Long-term diarrhoea leads to a potassium deficiency, so potassium supplements are necessary. At this price, it’s economical to buy a month's supply.
Polygonum Cuspidatum Complex
9.5
No side effects
Most Useful Review
I have a sensitive digestive system and was concerned about diarrhoea based on reviews. However, this product did not cause me any digestive issues. I highly recommend it.
8
Weight loss impact
Most Useful Review
After taking this product, I initially lost weight and had regular bowel movements. However, increasing my dosage led to diarrhoea and gas, so I reduced it back to one tablet a day. I'm pleased with the results and continue taking it.
Oregano
7
Oregano's limited effect on diarrhea
Potential benefits of early-life supplementation of liquid feed with fennel (Foeniculum vulgare) seeds or oregano (Origanum vulgare) leaves on growth, health, and blood metabolites in Holstein dairy calves.
Most Relevant Research
We investigated the effects of early-life supplementation of liquid feed with oregano leaf powder (OLP) on the health of Holstein dairy calves. Over the course of the study, we assessed not only growth performance but also health indicators, with a particular focus on diarrhea, a common issue in young calves.
The calves in the study were randomly assigned to receive either a standard liquid feed or one supplemented with OLP. While OLP treatment helped in decreasing the duration of diarrhea, it did not show a significant impact on the overall frequency of diarrhea episodes when compared to the control group receiving no supplementation.
Interestingly, calves that were supplemented with OLP experienced less severe health challenges compared to those without supplementation. Our results suggest that while OLP may not reduce the number of diarrhea days, it does contribute positively to the overall health and well-being of calves during this vulnerable stage.
In contrast, we also looked at fennel seed powder (FSP) as a supplement, which exhibited more noticeable benefits in growth and health parameters. This highlights the complexity of using herbal treatments, as oregano's effectiveness appears to be more limited in comparison to fennel.
The calves in the study were randomly assigned to receive either a standard liquid feed or one supplemented with OLP. While OLP treatment helped in decreasing the duration of diarrhea, it did not show a significant impact on the overall frequency of diarrhea episodes when compared to the control group receiving no supplementation.
Interestingly, calves that were supplemented with OLP experienced less severe health challenges compared to those without supplementation. Our results suggest that while OLP may not reduce the number of diarrhea days, it does contribute positively to the overall health and well-being of calves during this vulnerable stage.
In contrast, we also looked at fennel seed powder (FSP) as a supplement, which exhibited more noticeable benefits in growth and health parameters. This highlights the complexity of using herbal treatments, as oregano's effectiveness appears to be more limited in comparison to fennel.
8.8
Improved diarrhoea
Most Useful Review
Works on sibo. My diarrhoea has improved significantly.
Proprietary Blendmanna Fraxinus Ornus L)
9.5
Effective stool regulation
Most Useful Review
This tincture is fantastic! I have perfectly formed stools, and no diarrhoea. It truly is the best remedy.
8.8
Digestive discomfort relief
Most Useful Review
Good quality herbal preparation. It helps with digestion, relieving constipation and reducing diarrhoea symptoms. It also improves general well-being and supports skin health without artificial additives. I recommend it for overall health.
Vitamin B Complex
9.5
No side effects
Most Useful Review
This essential supplement is of high quality and does not cause diarrhoea or bloating as seen with some Russian vitamins.
Most Useful Review
Omega 3
8
Fatty acids combat swine viruses
DHA and EPA inhibit porcine coronavirus replication by alleviating ER stress.
Most Relevant Research
Our exploration into the impact of fatty acids, specifically eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), on porcine coronaviruses revealed noteworthy findings. We found that these acids significantly reduce the viral load of several dangerous porcine viruses, including the ones responsible for diarrhea in pigs, like porcine epidemic diarrhea virus (PEDV). This reduction occurs during viral replication, rather than hindering the virus's ability to enter the cells, indicating a specific action against the viral lifecycle.
We confirmed that both DHA and EPA help in reducing inflammation and lowering reactive oxygen species (ROS) levels within cells infected by these viruses. By doing so, they also enhance the overall antioxidant capacity of the cells, providing a protective effect against the stress caused by the viruses. Overall, our findings suggest that EPA, along with DHA, could play a critical role in developing new approaches to managing infection and, consequently, controlling outbreaks of diarrhea-causing viruses in the swine industry.
These findings are particularly relevant as we look for effective treatments to combat the viral threats facing livestock and, by extension, the agricultural economy. Thus, the antiviral properties of these fatty acids provide a promising avenue for future research and therapeutic development.
We confirmed that both DHA and EPA help in reducing inflammation and lowering reactive oxygen species (ROS) levels within cells infected by these viruses. By doing so, they also enhance the overall antioxidant capacity of the cells, providing a protective effect against the stress caused by the viruses. Overall, our findings suggest that EPA, along with DHA, could play a critical role in developing new approaches to managing infection and, consequently, controlling outbreaks of diarrhea-causing viruses in the swine industry.
These findings are particularly relevant as we look for effective treatments to combat the viral threats facing livestock and, by extension, the agricultural economy. Thus, the antiviral properties of these fatty acids provide a promising avenue for future research and therapeutic development.
8.8
No bad breath
Most Useful Review
It tastes excellent, does not cause bad breath, and I’ve not experienced any diarrhoea.
Lactoferrin
7
Lactoferrin alleviates PEDV diarrhea
Lactoferrin exhibits PEDV antiviral activity by interfering with spike-heparan sulfate proteoglycans binding and activating mucosal immune response.
Most Relevant Research
This study aimed to understand how lactoferrin can help reduce the impact of Porcine Epidemic Diarrhea Virus (PEDV), which causes severe diarrhea and high mortality in neonatal piglets. By investigating both laboratory and animal models, we observed that lactoferrin possesses antiviral properties that can inhibit PEDV replication.
Specifically, we found that lactoferrin may work by blocking the virus from binding to specific proteins on the surface of piglet cells. Additionally, our findings indicated that lactoferrin can enhance the immune response in piglets, boosting their intestinal defenses against the virus.
Overall, these results suggest that incorporating lactoferrin into the diets of pregnant sows could provide a layer of protection for their piglets against severe diarrhea caused by PEDV. By improving both direct antiviral action and immune function, lactoferrin represents a promising avenue for minimizing the devastation of this viral infection in young pigs.
Specifically, we found that lactoferrin may work by blocking the virus from binding to specific proteins on the surface of piglet cells. Additionally, our findings indicated that lactoferrin can enhance the immune response in piglets, boosting their intestinal defenses against the virus.
Overall, these results suggest that incorporating lactoferrin into the diets of pregnant sows could provide a layer of protection for their piglets against severe diarrhea caused by PEDV. By improving both direct antiviral action and immune function, lactoferrin represents a promising avenue for minimizing the devastation of this viral infection in young pigs.
9.5
Odour reduction
Most Useful Review
This is a supplement I frequently buy. Although the price has increased, I continue taking it for my intestinal health. Unless I consume a lot of fatty foods or desserts, I no longer notice any stool odour. I believe this has also eliminated body odour, particularly noticeable in summer. I even give a small amount to my dog, and he too has benefited from reduced stool odour. However, caution is advised when administering it to pets.
Fish Oil
8
Fatty acids combat swine viruses
DHA and EPA inhibit porcine coronavirus replication by alleviating ER stress.
Most Relevant Research
Our exploration into the impact of fatty acids, specifically eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), on porcine coronaviruses revealed noteworthy findings. We found that these acids significantly reduce the viral load of several dangerous porcine viruses, including the ones responsible for diarrhea in pigs, like porcine epidemic diarrhea virus (PEDV). This reduction occurs during viral replication, rather than hindering the virus's ability to enter the cells, indicating a specific action against the viral lifecycle.
We confirmed that both DHA and EPA help in reducing inflammation and lowering reactive oxygen species (ROS) levels within cells infected by these viruses. By doing so, they also enhance the overall antioxidant capacity of the cells, providing a protective effect against the stress caused by the viruses. Overall, our findings suggest that EPA, along with DHA, could play a critical role in developing new approaches to managing infection and, consequently, controlling outbreaks of diarrhea-causing viruses in the swine industry.
These findings are particularly relevant as we look for effective treatments to combat the viral threats facing livestock and, by extension, the agricultural economy. Thus, the antiviral properties of these fatty acids provide a promising avenue for future research and therapeutic development.
We confirmed that both DHA and EPA help in reducing inflammation and lowering reactive oxygen species (ROS) levels within cells infected by these viruses. By doing so, they also enhance the overall antioxidant capacity of the cells, providing a protective effect against the stress caused by the viruses. Overall, our findings suggest that EPA, along with DHA, could play a critical role in developing new approaches to managing infection and, consequently, controlling outbreaks of diarrhea-causing viruses in the swine industry.
These findings are particularly relevant as we look for effective treatments to combat the viral threats facing livestock and, by extension, the agricultural economy. Thus, the antiviral properties of these fatty acids provide a promising avenue for future research and therapeutic development.
9.5
Health improvements
Most Useful Review
Taking Omega-3 in tailored doses can lead to beneficial changes, such as reducing the risk of atherosclerosis and enhancing digestion. It may also normalise the menstrual cycle, improve sperm quality, and support heart health. Notably, Omega-3 may enhance cognitive skills and strengthen immunity, leading to better overall well-being and potentially alleviating issues like diarrhoea.
Protein
9
Probiotics enhance piglet growth
Dietary supplementation with alleviates diarrhea and improves growth performance and immune function in weaned piglets fed a high-protein diet.
Most Relevant Research
We set out to investigate how dietary protein influences diarrhea in weaned piglets. In our study, we divided 96 piglets into three groups: one on a low-protein diet, another on a high-protein diet, and the last on a high-protein diet enriched with probiotics.
Over 21 days, we observed significant differences in growth performance and diarrhea scores among the groups. The piglets receiving the high-protein diet with probiotics showed better average daily gains and higher feed intake compared to those on the low-protein diet. Interestingly, those on the high-protein diet alone had more frequent diarrhea episodes than those on the low-protein diet, while the addition of probiotics noticeably reduced diarrhea.
We also noticed improvements in nutrient digestibility and lower inflammatory markers in piglets that consumed the probiotic-enriched high-protein diet. They exhibited a healthier gut microbiota, with increased levels of beneficial bacteria that help with digestion and butyrate production, which is great for gut health.
Overall, our findings suggest that adding probiotics to a high-protein diet can effectively alleviate diarrhea and boost growth in weaned piglets, offering insights into improving livestock health and performance using dietary strategies.
Over 21 days, we observed significant differences in growth performance and diarrhea scores among the groups. The piglets receiving the high-protein diet with probiotics showed better average daily gains and higher feed intake compared to those on the low-protein diet. Interestingly, those on the high-protein diet alone had more frequent diarrhea episodes than those on the low-protein diet, while the addition of probiotics noticeably reduced diarrhea.
We also noticed improvements in nutrient digestibility and lower inflammatory markers in piglets that consumed the probiotic-enriched high-protein diet. They exhibited a healthier gut microbiota, with increased levels of beneficial bacteria that help with digestion and butyrate production, which is great for gut health.
Overall, our findings suggest that adding probiotics to a high-protein diet can effectively alleviate diarrhea and boost growth in weaned piglets, offering insights into improving livestock health and performance using dietary strategies.
Most Useful Review
Magnesium
9.5
Magnesium shows potential for diarrhea
Mg2+ supplementation treats secretory diarrhea in mice by activating calcium-sensing receptor in intestinal epithelial cells.
Most Relevant Research
We explored the impact of magnesium on secretory diarrhea, particularly in the context of cholera, a significant global health issue. The focus was on understanding how magnesium, often overlooked, could serve as an effective treatment option. In our study, we found that increasing levels of magnesium can significantly inhibit chloride secretion in intestinal cells, which is crucial during episodes of diarrhea.
We observed that magnesium, at concentrations typically seen in stool, reduced this secretory process by a remarkable 65%. This effect primarily occurs through a specific receptor in the intestinal cells known as the calcium-sensing receptor (CaSR). Interestingly, we noted that magnesium also counteracted Cl- secretion triggered by cholera toxin and other enterotoxins by about 50%.
Using mouse models, we saw that administering magnesium effectively decreased fluid loss associated with cholera by 40%. In a model mimicking the intestinal environment during cholera, adding magnesium not only curbed fluid secretion but also reversed it, promoting absorption instead. Given that patients suffering from cholera often have negligible magnesium levels in their stool, our findings suggest that oral magnesium supplementation could be a simple but effective therapeutic strategy for managing cholera and potentially other forms of secretory diarrhea.
We observed that magnesium, at concentrations typically seen in stool, reduced this secretory process by a remarkable 65%. This effect primarily occurs through a specific receptor in the intestinal cells known as the calcium-sensing receptor (CaSR). Interestingly, we noted that magnesium also counteracted Cl- secretion triggered by cholera toxin and other enterotoxins by about 50%.
Using mouse models, we saw that administering magnesium effectively decreased fluid loss associated with cholera by 40%. In a model mimicking the intestinal environment during cholera, adding magnesium not only curbed fluid secretion but also reversed it, promoting absorption instead. Given that patients suffering from cholera often have negligible magnesium levels in their stool, our findings suggest that oral magnesium supplementation could be a simple but effective therapeutic strategy for managing cholera and potentially other forms of secretory diarrhea.
9.5
No diarrhea issue
Most Useful Review
Delivery took six days, which I found impressive. I ordered magnesium glycinate for my mother, as it's better absorbed and doesn't cause diarrhoea. She's using it to prevent arthrosis and anaemia. The size is manageable, and I appreciate the quality packaging from Doctor's Best. I plan to explore more products from this brand. The effect of magnesium is easily noticeable.
Vitamin C
9
Vitamin C improves diarrheic calf health
Does vitamin C supplementation in milk improve growth and health of diarrheic calves?
Most Relevant Research
We investigated how adding vitamin C to milk influences the growth and health of young calves, particularly those experiencing diarrhea. The study involved 48 Holstein calves, which were sorted into two groups based on their health status: healthy calves and those with diarrhea. Each calf was fed the same amount of pasteurized milk and monitored until they reached 74 days of age.
Calves that received vitamin C showed an impressive increase in weight by weaning—74.3 kg compared to 72.2 kg for those without vitamin C. Additionally, calves treated with vitamin C demonstrated improved blood antioxidant levels, suggesting better overall health. Notably, calves suffering from diarrhea benefitted significantly from the vitamin C, needing fewer days of medication for treatment compared to those who did not receive the supplement.
The research highlights that vitamin C can play a critical role in supporting the health of calves during episodes of diarrhea. This is especially relevant for those that faced even mild cases early in life, as they seemed to gain the most benefits from the supplementation. Overall, it appears that vitamin C can positively impact both growth and health in calves suffering from diarrhea.
Calves that received vitamin C showed an impressive increase in weight by weaning—74.3 kg compared to 72.2 kg for those without vitamin C. Additionally, calves treated with vitamin C demonstrated improved blood antioxidant levels, suggesting better overall health. Notably, calves suffering from diarrhea benefitted significantly from the vitamin C, needing fewer days of medication for treatment compared to those who did not receive the supplement.
The research highlights that vitamin C can play a critical role in supporting the health of calves during episodes of diarrhea. This is especially relevant for those that faced even mild cases early in life, as they seemed to gain the most benefits from the supplementation. Overall, it appears that vitamin C can positively impact both growth and health in calves suffering from diarrhea.
9.5
Effective dosage
Most Useful Review
Best Vitamin C; water-soluble vitamins have a short effect but are effective long-term. Normal vitamin C causes diarrhoea, yet this 5g dose was okay.
Xylitol
8
Adapting to xylitol
Most Useful Review
I will never return to sugar after using this. It tastes just like sugar, is beneficial, and stable for baking. However, my body needed 1-2 weeks to adjust, and consuming over 60 grams can cause diarrhoea, though this stops once you're used to it.
8
Gradual consumption recommended
Most Useful Review
Xylitol is the best sugar substitute for a keto diet and beneficial for dental health. Gradual consumption is essential to avoid diarrhoea. If you find my review helpful, please give it a thumbs up.
Iron
9
Iron enhances piglet gut health
Dietary Fe-Gly supplementation attenuates enterotoxigenic (ETEC)-induced inflammation response and intestinal barrier dysfunction in piglets.
Most Relevant Research
We explored how adding iron, specifically Fe-Gly, to piglets' diets could help combat diarrhea caused by enterotoxigenic E. coli (ETEC) infections. In our study, we administered 50 mg of Fe-Gly to weaned piglets that had been infected, monitoring their growth, diarrhea rates, and overall gut health.
We observed remarkable improvements in the piglets' growth performance, with increases in average daily feed intake and daily gain by over 30%. Most notably, the rate of diarrhea significantly decreased by 40%. Additionally, we found that this iron supplementation raised the levels of total iron binding capacity in piglet serum, suggesting better iron transport and utilization.
Beyond growth metrics, the addition of Fe-Gly also showed potential in alleviating intestinal damage incurred from the ETEC challenge. As a result, we conclude that Fe-Gly not only meets daily iron needs but also reduces the iron available for harmful gut bacteria, promoting better intestinal health in piglets suffering from infections.
We observed remarkable improvements in the piglets' growth performance, with increases in average daily feed intake and daily gain by over 30%. Most notably, the rate of diarrhea significantly decreased by 40%. Additionally, we found that this iron supplementation raised the levels of total iron binding capacity in piglet serum, suggesting better iron transport and utilization.
Beyond growth metrics, the addition of Fe-Gly also showed potential in alleviating intestinal damage incurred from the ETEC challenge. As a result, we conclude that Fe-Gly not only meets daily iron needs but also reduces the iron available for harmful gut bacteria, promoting better intestinal health in piglets suffering from infections.
9.5
No diarrhea experienced
Most Useful Review
The best iron I have ever used. I experienced no side effects, and my analysis showed everything was fine. I used to have low haemoglobin, but now all indicators, including iron, are normal. The usual iron caused constant diarrhoea, which I do not recall with this product.
Coenzyme Q10
7
Riboflavin may improve symptoms
Therapeutic trial in the first three Asian cases of ethylmalonic encephalopathy: response to riboflavin.
Most Relevant Research
We observed three Korean girls suffering from ethylmalonic encephalopathy, marking the first known cases in Asia. Through treatment with riboflavin and coenzyme Q10, we noted slight improvements in their motor functions, cognitive behaviors, and notably, their chronic mucoid diarrhea.
Although the improvements were modest, the connection between these treatments and their impact on diarrhea is intriguing. It's worth mentioning that since both riboflavin and coenzyme Q10 were used in the study, we cannot definitively isolate the effects of coenzyme Q10 on diarrhea alone.
The precise cause of ethylmalonic encephalopathy is still unclear, but our findings suggest that riboflavin may offer some benefit. Overall, while we didn't see a significant breakthrough regarding diarrhea, the potential of these treatments warrants further exploration to understand their full effects.
Although the improvements were modest, the connection between these treatments and their impact on diarrhea is intriguing. It's worth mentioning that since both riboflavin and coenzyme Q10 were used in the study, we cannot definitively isolate the effects of coenzyme Q10 on diarrhea alone.
The precise cause of ethylmalonic encephalopathy is still unclear, but our findings suggest that riboflavin may offer some benefit. Overall, while we didn't see a significant breakthrough regarding diarrhea, the potential of these treatments warrants further exploration to understand their full effects.
Most Useful Review
Calcium
8
Light coffee may ease diarrhea
Antispasmodic Activity of Light-Roasted Coffee Extract and Its Potential Use in Gastrointestinal Motility Disorders.
Most Relevant Research
We investigated how extracts from light, medium, and dark roasted coffee beans affect contractions in the ileum, which is part of the intestine. The aim was to see if these coffee extracts could help manage gastrointestinal motility disorders like diarrhea.
During our experiments, we noticed that all coffee extracts reduced spontaneous contractions of rat ileum tissue in a dose-dependent manner. However, it was the light coffee extract that stood out, showing the most significant reduction in ileal contractions, especially at higher concentrations.
Our findings suggested that the antispasmodic effects of light coffee might be linked to its ability to inhibit calcium influx or interfere with calcium signaling pathways, which are crucial in muscle contractions. We found that certain compounds in the light coffee, such as chlorogenic acid and caffeine, likely contributed to this effect. Overall, our study indicates that light-roasted coffee has the potential to help manage conditions related to intestinal spasms and diarrhea.
During our experiments, we noticed that all coffee extracts reduced spontaneous contractions of rat ileum tissue in a dose-dependent manner. However, it was the light coffee extract that stood out, showing the most significant reduction in ileal contractions, especially at higher concentrations.
Our findings suggested that the antispasmodic effects of light coffee might be linked to its ability to inhibit calcium influx or interfere with calcium signaling pathways, which are crucial in muscle contractions. We found that certain compounds in the light coffee, such as chlorogenic acid and caffeine, likely contributed to this effect. Overall, our study indicates that light-roasted coffee has the potential to help manage conditions related to intestinal spasms and diarrhea.
9
Softens stool
Most Useful Review
After eliminating dairy due to lactose intolerance, I realised the importance of calcium, which this supplement provides along with magnesium for better absorption. It effectively softens stool without causing diarrhoea, although the tablet size is quite large.