Products best matching hypothyroidism

Vitamins

7
Vitamin D and hypothyroidism explored
The Effect of Some Micronutrients Multi-Supplementation on Thyroid Function, Metabolic Features and Quality of Life in Patients Treating With Levothyroxine and Vitamin D: A Double-blind, Randomized Controlled Trial.
Most Relevant Research
We conducted a thoughtful exploration into how vitamin D and other micronutrients might influence hypothyroidism, particularly looking at thyroid function, metabolism, and quality of life. In this double-blind, randomized controlled trial, we involved 104 patients who were already receiving levothyroxine for their hypothyroidism. They were split into two groups; one received a combination of micronutrients, including vitamin D, while the other group received a placebo.

After eight weeks, we observed some impacts on insulin resistance and quality of life among those receiving the micronutrient supplement, suggesting that these nutrients could play a role in improving overall well-being in hypothyroid patients. However, while vitamin D is part of the treatment, we found it challenging to isolate its direct effect due to its combination with other nutrients.

Ultimately, while our findings indicate potential benefits, they also emphasize the need for further clinical trials to confirm these results and better understand the role of vitamin D in managing hypothyroidism.
8.8
Effective treatment
Most Useful Review
With atopic dermatitis, I find the ideal formula is to take D3 and Omega-3 at breakfast, Vitamin A afterwards, and Vitamin E later. For hypothyroidism, Vitamin A acts as a cofactor for iodine. Given its price and quality, Vitamin A is exceptional.

Vitamin Bs

9
Thiamin improves memory in hypothyroidism
Ameliorative effects of thiamin on learning behavior and memory dysfunction in a rat model of hypothyroidism: implication of oxidative stress and acetylcholinesterase.
Most Relevant Research
Our study focused on how thiamin, also known as Vitamin B1, can help with learning and memory issues caused by hypothyroidism. We designed an experiment using 50 rats, which we treated with propylthiouracil to induce hypothyroidism and then supplemented with varying doses of thiamin. Over a period of seven weeks, we assessed the rats’ abilities to remember and learn through standard tests like the Morris water maze and passive avoidance tasks.

We observed that thiamin significantly improved the ability of hypothyroid rats to recall the location of a hidden platform in the water maze. The rats that received higher doses of thiamin spent less time finding the platform and traveled shorter distances compared to those in the hypothyroid group who did not receive the supplement. Similarly, in the passive avoidance test, rats treated with thiamin demonstrated longer delays before entering a dark chamber, indicating improved memory retention.

Additionally, thiamin showed promise in reducing oxidative stress and decreasing acetylcholinesterase activity in the brain. This suggests that thiamin may help to rebalance certain chemicals in the brain, contributing to better memory function. Overall, our findings support the potential benefits of thiamin for addressing learning and memory deficits in cases of hypothyroidism, primarily by improving oxidative status and cholinergic function.
9.5
Stopped hair loss
Most Useful Review
After three months of taking this supplement, my hair loss has stopped, and my nails are stronger. I have chemical sensitivity and hypothyroidism, both of which contribute to hair loss. This supplement has a higher content of ingredients compared to Japanese biotin, and it has helped my hair and skin feel better. I even take more on days with strong chemicals due to its detoxifying properties.

Iron

9.5
Improved energy
Most Useful Review
Super supplement! I've suffered from iron deficiency and hypothyroidism for years. Nothing helped until I tried this chelated iron. It greatly improved my condition, eliminating dizziness and fatigue. I take it regularly and will continue to monitor my ferritin levels. Overall, it’s a fantastic product for managing my iron levels.
9.5
No side effects
Most Useful Review
I highly recommend this iron supplement for hypothyroidism. Previous gentle iron options caused discomfort, but this one does not. I take it daily, and my blood tests now show no deficiency. I keep buying it as it works well without side effects.

Ubiquinol

8.8
Improves energy levels
Most Useful Review
I take this alongside Omega-3 and CLA to enhance my metabolism and energy levels, as I tend to tire easily due to chronic hypothyroidism. Ubiquinol is also advised for kidney and vascular diseases. I feel better on this supplement. I take it after meals, and the gel capsules are easy to swallow, without causing any side effects.
9.5
Increases strength
Most Useful Review
I have completely lost my thyroid gland due to hypothyroidism. For two years, I’ve taken ubiquinol with omega daily. It provides me with strength and energy, even during fasting. Many of my friends now take it. It’s an essential supplement for memory and brain function, replacing my previous medications, and I always stock up on it.

L Theanine

7
Myo-inositol's limited impact on thyroid
Role of Supplementation with Selenium and Myo-Inositol Versus Selenium Alone in Patients of Autoimmune Thyroiditis: A Systematic Review and Meta-Analysis.
Most Relevant Research
We explored the effectiveness of myo-inositol in combination with selenium for treating autoimmune thyroiditis (AIT) and how this combination impacts thyroid hormone levels. Through a systematic review and meta-analysis of various studies, we found that supplementing selenium with myo-inositol led to a significant reduction in thyroid-stimulating hormone (TSH) levels compared to taking selenium alone. Additionally, we observed a notable decline in thyroglobulin antibodies (TgAb) in the combined treatment group.

However, it’s important to note that while TSH and TgAb levels showed improvement, the levels of thyroid peroxidase antibodies (TPOAb), T3, and T4 were not significantly affected by the addition of myo-inositol. This indicates that while there can be benefits to using inositol alongside selenium, it doesn’t appear to have a strong standalone effect on hypothyroidism. Our findings suggest the need for further research to fully understand the role of myo-inositol in thyroid health and its potential contributions to restoring a healthy thyroid function.
8.8
Improved concentration
Most Useful Review
I have hypothyroidism but enjoy coffee in the morning, paired with L-Theanine, which enhances the effect. Caffeine alone causes a sharp energy spike followed by a drop, whereas combining it with L-Theanine results in a smoother, longer-lasting boost in focus and mood. It aids my memory, suppresses appetite, and doesn’t induce drowsiness. Occasionally, I take it with melatonin at night to help me sleep, always on an empty stomach for greater potency. I love it and always keep it stocked!

Eicosapentaenoic Acid

9
Eicosapentaenoic Acid supports brain development
Anti-apoptotic role of omega-3-fatty acids in developing brain: perinatal hypothyroid rat cerebellum as apoptotic model.
Most Relevant Research
We investigated the role of eicosapentaenoic acid (EPA), an omega-3 fatty acid, in the context of hypothyroidism and its effects on brain development. Our study used a rat model where hypothyroidism was induced, allowing us to examine how EPA influences neuronal health during this critical phase of development.

Through our research, we found that supplementing EPA, along with docosahexaenoic acid (DHA), significantly reduced signs of neuronal apoptosis, which is a controlled process of cell death that can be detrimental when excessive. Specifically, we observed decreases in DNA fragmentation and activation of an important mediator of cell death—caspase-3—in the cerebella of hypothyroid pups.

One of the key findings highlighted that EPA helped counteract increases in a pro-apoptotic protein called Bax. At the same time, levels of protective proteins, such as Bcl-2 and Bcl-x(L), were restored, which are crucial in promoting cell survival. Additionally, EPA supplementation normalized several important signaling pathways affected by thyroid hormone deficiency, which play vital roles in neuronal health.

Overall, our findings contribute valuable insight into how eicosapentaenoic acid can offer protective benefits for brain development during periods of stress caused by hypothyroidism, illuminating potential therapeutic pathways for ongoing investigations.
9.5
Essential for treatment
Most Useful Review
My endocrinologist recommended this brand of Omega 3 for treating my hypothyroidism as fish oil is crucial for my condition.

Probiotics

7
Brewer's yeast mitigates adrenal atrophy
Protective effect of Brewer's yeast on methimazole-induced-adrenal atrophy (a stereological study).
Most Relevant Research
We explored the protective role of brewer's yeast in combating the harmful effects of methimazole-induced hypothyroidism. In a study involving 48 rats, we divided them into control and experimental groups to assess the impact of methimazole and brewer's yeast on adrenal glands.

Our findings showed that methimazole led to reduced adrenal size and lower cortisol levels. However, when brewer's yeast was administered alongside methimazole, it significantly lessened these adverse effects, suggesting a natural remedy might help safeguard adrenal health during hypothyroidism treatment.
9.5
Reduced insulin level
Most Useful Review
This berberine was prescribed by my endocrinologist. I had hypothyroidism with insulin resistance. After six months of taking omega-3, D3, magnesium, MCT oil, folic acid, and having 1-2 meals a day, my insulin level decreased from 31.1 to 15.2. While I aim for further reduction, I believe this is a good result. Additionally, I've lost weight through swimming and walking 10,000 steps daily. Importantly, all my thyroid hormones are now normal!

Fish Oil

8
Omega 3 protects against thyroid damage
Omega 3 fatty acids preserve testicular function by ameliorating BPF-induced dysthyroidism: role of p53/Bcl-2 signaling and proton pump activities.
Most Relevant Research
We observed the effects of Omega 3 fatty acids (O3FA) on hypothyroidism caused by the endocrine-disrupting chemical Bisphenol F (BPF) in a controlled study with male Wistar rats. The rats were divided into four groups: a control group, a BPF-only group, and two intervention groups receiving different doses of O3FA alongside BPF.

Our findings revealed that both low and high doses of O3FA significantly improved sperm quality, hormonal levels, and antioxidant defenses, which were adversely affected by BPF. Notably, the treatment with O3FA restored important enzymes and prevented harmful increases in certain inflammatory markers, showing its protective role against testicular dysfunction linked to thyroid issues.

Overall, this study indicates that incorporating Omega 3 fatty acids could be an effective strategy to counteract the negative impacts of BPF-induced hypothyroidism and support male reproductive health.
9.5
Improved well-being
Most Useful Review
Chewable tablets are delightful! I have hypothyroidism and high homocysteine. I take this B12 alongside other supplements, and after a month, I feel fantastic! The dosage is optimal, replenishing my deficiency while reducing homocysteine. I regularly remember to take it because they taste good, and B12 is better absorbed sublingually through the oral mucosa. A great addition!

Zinc

7
Zinc's uncertain role in hypothyroidism
The Effect of Some Micronutrients Multi-Supplementation on Thyroid Function, Metabolic Features and Quality of Life in Patients Treating With Levothyroxine and Vitamin D: A Double-blind, Randomized Controlled Trial.
Most Relevant Research
We conducted a study to investigate the effects of micronutrient supplementation, including zinc, on thyroid function and overall quality of life in patients with hypothyroidism. Our trial involved 104 participants who were receiving levothyroxine and vitamin D. They were randomly assigned to either a group that received a mix of essential nutrients or a placebo group over eight weeks.

We measured various health markers before and after this period, including thyroid hormone levels, cholesterol, insulin resistance, and blood pressure. Our findings suggested that the group receiving the micronutrient supplement experienced improvements in insulin resistance and overall quality of life. However, it’s important to note that the specific effects of zinc alone are somewhat difficult to isolate, as it was part of a combination of nutrients being tested.

Ultimately, while the study indicates potential benefits of micronutrient supplementation for thyroid function in hypothyroid patients, further trials are necessary to clearly define the role of zinc and other nutrients in this context.
8.8
Improved life quality
Most Useful Review
I have hypothyroidism and a zinc deficiency, resulting in various health issues. I experience hair loss, fatigue, and more. Zinc intake is crucial for thyroid function and hormone regulation. I opt for zinc chelate as its bioavailability is higher. While other medications also contribute to my treatment, zinc has significantly enhanced my quality of life. I also provide it to my family to bolster their immunity.

Omega 3

9
Omega 3 aids testicular function
Omega 3 fatty acids preserve testicular function by ameliorating BPF-induced dysthyroidism: role of p53/Bcl-2 signaling and proton pump activities.
Most Relevant Research
We explored the impact of omega 3 fatty acids (O3FA) on hypothyroidism triggered by bisphenol F (BPF), a chemical known to disrupt endocrine functions. The study involved 20 male Wistar rats, divided into groups to either receive BPF, O3FA, or a combination of both for a duration of 28 days. This design helped us assess the protective effects of O3FA against hypothyroidism-related testicular dysfunction.

Our findings revealed that both low and high doses of O3FA were effective in improving various indicators of reproductive health. Specifically, we observed enhancements in sperm quality and hormone levels, including testosterone and luteinizing hormone. Additionally, O3FA increased antioxidant defenses and reduced harmful markers associated with oxidative stress.

On a cellular level, we noted that O3FA countered BPF's adverse effects on critical processes in the body, including energy production and apoptosis (cell death). This was linked to restoring a balance between proteins that promote cell survival and those that trigger cell death. Overall, the study underscores the potential of omega 3 fatty acids as a therapeutic intervention for testicular dysfunction arising from hypothyroidism.
9.5
Miraculous skin improvement
Most Useful Review
My first omega-3, recommended by my endocrinologist, needed for my hypothyroidism. Initially, my skin was extremely dry and sensitive, but after taking Omega for about a month, I noticed a significant improvement. My skin now remains better hydrated even after washing. I take two capsules daily after meals. I previously tried Finnish and Norwegian omega, but I prefer this one, despite the large capsule size. Highly recommend it!

Ginkgo

7
Ginkgo biloba supports hypothyroidism treatment
Treatment with Ginkgo biloba supplement modulates oxidative disturbances, inflammation and vascular functions in oxygen deprived hypothyroid mice: Involvement of endothelin-1/NO signaling pathways.
Most Relevant Research
We investigated how Ginkgo biloba could help balance some of the challenges faced by hypothyroid mice under conditions of oxygen deprivation. In our study, we divided male Swiss mice into five groups, where some received Ginkgo biloba, while others were treated with Levothyroxine or were left untreated as controls.

We observed that Ginkgo biloba didn’t boost thyroid hormone levels, but it helped keep TSH levels steady. After treatment, the mice showed lower blood glucose, decreased oxidative stress, and inflammation, indicating a positive shift in their biochemical balance. This suggests Ginkgo biloba may reduce harmful effects related to hypoxia and hypothyroidism.

Importantly, we noticed Ginkgo biloba affected the signaling pathways involving endothelin-1 and nitric oxide in the aorta, which are crucial for vascular health. Overall, Ginkgo biloba appears to act as a therapeutic candidate, potentially offering a natural way to support cardiovascular function in hypothyroid conditions affected by low oxygen levels.
9.5
Improved focus
Most Useful Review
Promotes clarity and focus! After battling brain fog due to hypothyroidism for years, I was eager for a solution. My grades in my postgraduate course were barely average as I struggled to form sentences for assignments and often forgot what I had read. However, with this brand, I felt energised, focused, and my memory improved significantly. I have a positive experience every time I take it, regardless of breaks in usage. It works anytime I take it.

Vitamin D3

8
Vitamin D3 improves thyroid function
Effects of vitamin D supplementation on autoantibodies and thyroid function in patients with Hashimoto's thyroiditis: A systematic review and meta-analysis.
Most Relevant Research
We evaluated the effects of vitamin D3 supplementation on hypothyroidism, specifically in patients with Hashimoto's thyroiditis (HT). Our analysis involved 12 randomized controlled trials, comparing the outcomes of individuals receiving vitamin D3 against those given a placebo or no treatment at all.

Through this thorough examination, we found that vitamin D3 did promote significant improvements in thyroid function and immune response. Specifically, we observed a reduction in two key antibodies: anti-thyroid peroxidase (TPO-Ab) and thyroglobulin antibody (TG-Ab). These reductions suggest a positive effect on the autoimmune process involved in Hashimoto's thyroiditis.

Additionally, we noted improvements in thyroid hormone levels, including free thyroxine (FT4) and free triiodothyronine (FT3), while thyroid-stimulating hormone (TSH) levels showed a decrease. These findings indicate that vitamin D3 supplementation may benefit thyroid health and help manage hypothyroidism more effectively.

For those considering vitamin D3 as a treatment option, particularly those who have been on vitamin D for longer than 12 weeks, the results suggest a more pronounced effect on improving antibody levels and thyroid function. Thus, there appears to be a compelling case for vitamin D3 as a supportive treatment in managing Hashimoto's thyroiditis and related hypothyroidism.
8.8
Improved mood
Most Useful Review
The mood has improved, and my TTG has decreased. I have hypothyroidism, and after taking vitamin D, my levels rose, leading to better well-being. A doctor prescribed 50,000 IU (one tablet every other day) for three weeks, with a follow-up on vitamin D levels due to individual digestibility variations.

Magnesium

7
Magnesium's role in hypothyroidism
The Effect of Some Micronutrients Multi-Supplementation on Thyroid Function, Metabolic Features and Quality of Life in Patients Treating With Levothyroxine and Vitamin D: A Double-blind, Randomized Controlled Trial.
Most Relevant Research
We explored how magnesium, as part of a broader supplementation strategy, influences thyroid function and overall well-being in patients with hypothyroidism. In a well-structured study, 104 individuals receiving traditional treatment with levothyroxine and vitamin D were randomly divided into two groups. One group received a combination of essential micronutrients, including magnesium, while the other received placebos over an 8-week period.

Our observations highlighted changes in insulin resistance and quality of life after the intervention, suggesting that micronutrient supplementation could have a bearing on these aspects of health. However, the specifics regarding magnesium's isolated effect on thyroid function were less clear due to the multi-nutritional approach taken in this trial.

While we acknowledge promising results related to quality of life, we must clarify that the study does not provide concrete evidence that magnesium alone significantly improves thyroid function. Further, more focused clinical trials are necessary to ascertain the role of magnesium, allowing for a better understanding of its potential benefits in hypothyroid patients.
9.5
Effective supplement
Most Useful Review
After being diagnosed with hypothyroidism and trying hormonal therapy with no improvement, I decided to try magnesium. I've been taking it for less than a week, and I already feel better—no more freezing limbs or constipation. This supplement genuinely works!

Coenzyme Q10

7
Coenzyme Q10 shows potential benefits
Proof of concept of the WOMED model of benign thyroid disease: Restitution of thyroid morphology after correction of physical and psychological stressors and magnesium supplementation.
Most Relevant Research
We explored the effects of a combination of magnesium, selenium, and coenzyme Q10 on the thyroid morphology in patients suffering from benign thyroid diseases, specifically looking at both hyperthyroidism and hypothyroidism. Our study involved 8 patients who received standard pharmacological treatment but also underwent additional therapy at our private institution.

Over a period of 2 to 4 years, we observed some remarkable changes. Initially, we addressed musculoskeletal issues and psychological stressors in our patients. Following this, thyroid morphology started to normalize, with improvements visible through ultrasound imaging. Notably, thyroid antibody levels declined in most patients, suggesting a positive response to the treatment.

However, it's essential to highlight that we could not assess the isolated impact of coenzyme Q10 on hypothyroidism specifically, as it was part of a broader treatment regimen. While we saw promising results, we encountered limited success in two cases where chronic thyroiditis had persisted for over ten years, suggesting that factors like fibrosis may influence treatment outcomes.

Overall, despite the small sample size, our findings challenge the idea that thyroid issues are perpetually autoimmune and irreversible, opening up new avenues for therapeutic options for patients with thyroid diseases.
9.5
Supports thyroid recovery
Most Useful Review
I have bought this product multiple times for heart health. My husband has taken it for over five years, witnessing substantial improvement in his heart condition. I started it this year for my hypothyroidism and hyperlipidemia, and it appears to aid in restoring thyroid function while protecting cardiovascular health.