Last update
4/17/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
USERS' SCORE
Moderately Good
Based on 87 Reviews
7.6
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Milk Thistle Extract(Silybum marianum) (Fruit/Seed)(Standardized to 240 mg Silymarin Flavonoids - equivalent 80%)
300 mg
**
Dandelion Root (Taraxacum officinale)
100 mg
**
Artichoke (Cynara scolymus) (Leaf)
50 mg
**
Top Medical Research Studies
8
We explored the potential of intravenous silibinin, a milk thistle extract, in treating an HIV-HCV coinfected patient who didn't respond to standard therapy. After just two weeks of silibinin treatment, both HCV and HIV levels became undetectable.
While silibinin appeared promising, leading to a trend of increased CD4+ cells, the follow-up showed that HIV levels returned to their previous state after stopping additional therapy.
These findings suggest that while silibinin may help some, more research is needed to understand its benefits fully.
While silibinin appeared promising, leading to a trend of increased CD4+ cells, the follow-up showed that HIV levels returned to their previous state after stopping additional therapy.
These findings suggest that while silibinin may help some, more research is needed to understand its benefits fully.
Read More
8
We directly evaluated the effects of silymarin, or milk thistle extract, on hepatitis C virus (HCV) infection and liver protection.
Our study found that while silymarin does show some promise in reducing oxidative stress and inflammation, it didn't consistently surpass the potency of its individual flavonolignan compounds in battling the virus.
Overall, these findings indicate that silymarin-derived compounds could influence the progression of HCV in certain patients.
However, further research is needed to pinpoint clinical outcomes with standardized doses.
Our study found that while silymarin does show some promise in reducing oxidative stress and inflammation, it didn't consistently surpass the potency of its individual flavonolignan compounds in battling the virus.
Overall, these findings indicate that silymarin-derived compounds could influence the progression of HCV in certain patients.
However, further research is needed to pinpoint clinical outcomes with standardized doses.
Read More
4
We examined the use of silymarin, a popular herbal extract from milk thistle, among participants in the HALT-C Trial, focused on individuals with chronic hepatitis C. Our findings indicated that while many people were eager to utilize silymarin hoping to enhance treatment outcomes, there was no significant effect on liver enzyme levels or hepatitis C virus activity.
However, those taking silymarin reported fewer symptoms and somewhat better quality of life. Ultimately, since this study was observational, we believe more rigorous research is necessary to conclusively determine the benefits of silymarin for hepatitis C patients.
However, those taking silymarin reported fewer symptoms and somewhat better quality of life. Ultimately, since this study was observational, we believe more rigorous research is necessary to conclusively determine the benefits of silymarin for hepatitis C patients.
Read More
Most Useful Reviews
8
Normalised liver tests
237 people found this helpful
Excellent! A very good preparation for the liver. After Covid, my doctor prescribed milk thistle and essential oil to support my liver. Often, drugs prescribed for COVID-19 are hepatotoxic and can overload the liver, potentially leading to drug-induced hepatitis. I think everyone's heard of the advertising favourite, Karsil, which contains silymarin as its active substance. In one capsule of this supplement, there is 300 mg, which is significantly more than Karsil. After a month on this treatment, my tests returned to normal, the heaviness after meals vanished, and I even lost 4kg. Overall, a fantastic product that I highly recommend!
Read More
9
Rejuvenated liver cells
78 people found this helpful
Excellent for restoring the liver! This product acts as a great substitute for Karsil at a reasonable price! It accelerates liver cell regeneration and inhibits enzymes that lead to peroxidation, making it ideal for protecting the liver from alcohol, smoke, and various medications. It also aids in lowering bilirubin levels and enhances bile flow, proving effective against various forms of hepatitis and liver damage from toxic substances. I'm very pleased with the outcomes from using this supplement!
Read More
6
Liver cleansing remedy
51 people found this helpful
My grandmother takes Milk Thistle for liver cleansing after Hepatitis, as it has antiviral and anti-inflammatory properties. We're both pleased with its effects, and I will provide further feedback in the future.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
- All Researches
8
We explored the potential of intravenous silibinin, a milk thistle extract, in treating an HIV-HCV coinfected patient who didn't respond to standard therapy. After just two weeks of silibinin treatment, both HCV and HIV levels became undetectable.
While silibinin appeared promising, leading to a trend of increased CD4+ cells, the follow-up showed that HIV levels returned to their previous state after stopping additional therapy.
These findings suggest that while silibinin may help some, more research is needed to understand its benefits fully.
While silibinin appeared promising, leading to a trend of increased CD4+ cells, the follow-up showed that HIV levels returned to their previous state after stopping additional therapy.
These findings suggest that while silibinin may help some, more research is needed to understand its benefits fully.
Read More
8
We directly evaluated the effects of silymarin, or milk thistle extract, on hepatitis C virus (HCV) infection and liver protection.
Our study found that while silymarin does show some promise in reducing oxidative stress and inflammation, it didn't consistently surpass the potency of its individual flavonolignan compounds in battling the virus.
Overall, these findings indicate that silymarin-derived compounds could influence the progression of HCV in certain patients.
However, further research is needed to pinpoint clinical outcomes with standardized doses.
Our study found that while silymarin does show some promise in reducing oxidative stress and inflammation, it didn't consistently surpass the potency of its individual flavonolignan compounds in battling the virus.
Overall, these findings indicate that silymarin-derived compounds could influence the progression of HCV in certain patients.
However, further research is needed to pinpoint clinical outcomes with standardized doses.
Read More
4
We examined the use of silymarin, a popular herbal extract from milk thistle, among participants in the HALT-C Trial, focused on individuals with chronic hepatitis C. Our findings indicated that while many people were eager to utilize silymarin hoping to enhance treatment outcomes, there was no significant effect on liver enzyme levels or hepatitis C virus activity.
However, those taking silymarin reported fewer symptoms and somewhat better quality of life. Ultimately, since this study was observational, we believe more rigorous research is necessary to conclusively determine the benefits of silymarin for hepatitis C patients.
However, those taking silymarin reported fewer symptoms and somewhat better quality of life. Ultimately, since this study was observational, we believe more rigorous research is necessary to conclusively determine the benefits of silymarin for hepatitis C patients.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 87 Reviews
7.6
- All Reviews
- Positive Reviews
- Negative Reviews
8
Normalised liver tests
237 people found this helpful
Excellent! A very good preparation for the liver. After Covid, my doctor prescribed milk thistle and essential oil to support my liver. Often, drugs prescribed for COVID-19 are hepatotoxic and can overload the liver, potentially leading to drug-induced hepatitis. I think everyone's heard of the advertising favourite, Karsil, which contains silymarin as its active substance. In one capsule of this supplement, there is 300 mg, which is significantly more than Karsil. After a month on this treatment, my tests returned to normal, the heaviness after meals vanished, and I even lost 4kg. Overall, a fantastic product that I highly recommend!
Read More
9
Rejuvenated liver cells
78 people found this helpful
Excellent for restoring the liver! This product acts as a great substitute for Karsil at a reasonable price! It accelerates liver cell regeneration and inhibits enzymes that lead to peroxidation, making it ideal for protecting the liver from alcohol, smoke, and various medications. It also aids in lowering bilirubin levels and enhances bile flow, proving effective against various forms of hepatitis and liver damage from toxic substances. I'm very pleased with the outcomes from using this supplement!
Read More
6
Liver cleansing remedy
51 people found this helpful
My grandmother takes Milk Thistle for liver cleansing after Hepatitis, as it has antiviral and anti-inflammatory properties. We're both pleased with its effects, and I will provide further feedback in the future.
Read More
6
Improved skin condition
34 people found this helpful
I have a history of liver cancer and hepatitis B. I've undergone surgery twice to remove liver tumours and took milk thistle with lecithin to help repair my liver. Within a few weeks, I noticed a significant improvement; my skin rashes diminished, and my wounds healed faster.
Read More
6
Lowered liver indicators
32 people found this helpful
I completed a month-long course of this supplement for cholestasis. Though I didn't see any immediate effects, my sister, who has liver issues, experienced a decline in her liver indicators after using it for a month. This supplement, combined with other liver-supporting products, may yield ongoing benefits for liver health.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Payer BA, Reiberger T, Rutter K, Beinhardt S, Staettermayer AF, et al. Successful HCV eradication and inhibition of HIV replication by intravenous silibinin in an HIV-HCV coinfected patient. J Clin Virol. 2010;49:131. 10.1016/j.jcv.2010.07.006
- Polyak SJ, Morishima C, Lohmann V, Pal S, Lee DY, et al. Identification of hepatoprotective flavonolignans from silymarin. Proc Natl Acad Sci U S A. 2010;107:5995. 10.1073/pnas.0914009107
- Seeff LB, Curto TM, Szabo G, Everson GT, Bonkovsky HL, et al. Herbal product use by persons enrolled in the hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial. Hepatology. 2008;47:605. PubMed
