Last update
4/17/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
USERS' SCORE
Good
Based on 9 Reviews
8.6
Supplement Facts
Serving Size: 2 Softgels
Amount Per Serving
%DV
Milk Thistle Phospholipid Proprietary BlendMilk thistle extract (fruit) [providing 480 mg silymarin, 180 mg silybin, 48 mg isosilybin A and isosilybin B], phospholipids
760 mg
**
SILIPHOS® phytosome milk thistle extract (fruit) [providing 47.52 mg silybin]
160 mg
**
Top Medical Research Studies
8
We explored the potential of intravenous silibinin, a milk thistle extract, in treating an HIV-HCV coinfected patient who didn't respond to standard therapy. After just two weeks of silibinin treatment, both HCV and HIV levels became undetectable.
While silibinin appeared promising, leading to a trend of increased CD4+ cells, the follow-up showed that HIV levels returned to their previous state after stopping additional therapy.
These findings suggest that while silibinin may help some, more research is needed to understand its benefits fully.
While silibinin appeared promising, leading to a trend of increased CD4+ cells, the follow-up showed that HIV levels returned to their previous state after stopping additional therapy.
These findings suggest that while silibinin may help some, more research is needed to understand its benefits fully.
Read More
8
We directly evaluated the effects of silymarin, or milk thistle extract, on hepatitis C virus (HCV) infection and liver protection.
Our study found that while silymarin does show some promise in reducing oxidative stress and inflammation, it didn't consistently surpass the potency of its individual flavonolignan compounds in battling the virus.
Overall, these findings indicate that silymarin-derived compounds could influence the progression of HCV in certain patients.
However, further research is needed to pinpoint clinical outcomes with standardized doses.
Our study found that while silymarin does show some promise in reducing oxidative stress and inflammation, it didn't consistently surpass the potency of its individual flavonolignan compounds in battling the virus.
Overall, these findings indicate that silymarin-derived compounds could influence the progression of HCV in certain patients.
However, further research is needed to pinpoint clinical outcomes with standardized doses.
Read More
4
We examined the use of silymarin, a popular herbal extract from milk thistle, among participants in the HALT-C Trial, focused on individuals with chronic hepatitis C. Our findings indicated that while many people were eager to utilize silymarin hoping to enhance treatment outcomes, there was no significant effect on liver enzyme levels or hepatitis C virus activity.
However, those taking silymarin reported fewer symptoms and somewhat better quality of life. Ultimately, since this study was observational, we believe more rigorous research is necessary to conclusively determine the benefits of silymarin for hepatitis C patients.
However, those taking silymarin reported fewer symptoms and somewhat better quality of life. Ultimately, since this study was observational, we believe more rigorous research is necessary to conclusively determine the benefits of silymarin for hepatitis C patients.
Read More
Most Useful Reviews
9
Effective liver support
97 people found this helpful
One of the best liver drugs for both prevention and treatment! I occasionally purchase this product for my mother, who suffers from chronic viral hepatitis, as liver support is vital for her. Milk thistle ranks highly among hepatic herbs due to its efficacy. The bioactive compound silybin is not water-soluble, which hinders absorption. However, with phosphatidylcholine encapsulating silybin, its bioavailability for the liver is significantly enhanced, making it ten times more effective than pure silymarin. This results in better protection of liver cells, detoxification, stimulation of healthy cell growth, bile production, and reduced autoimmune reactions. My mother is pleased with the results, confirmed by analyses, taking it at night during optimal liver bioactivity.
Read More
9
Dermatitis relief
10 people found this helpful
Excellent composition! I bought it to support my liver, as I have had hepatitis B since childhood. The liver is the primary barrier against toxins. When overwhelmed, it fails to protect effectively, leading to various health issues, including dermatitis. After a month on ordinary milk thistle, I switched to these capsules, taking two daily before meals. Positive results take at least three months, but remarkably, my dermatitis has cleared for the first time in two years! I maintain a healthy lifestyle, avoiding alcohol. This milk thistle really worked wonders for me! Thank you for reading.
Read More
7.5
Liver health improving
10 people found this helpful
I have hepatitis C and take milk thistle capsules regularly. My liver feels better. The capsule size is convenient, and the ingredients are reliable. I take one capsule twice daily. I've tested this manufacturer's products multiple times, and I trust they will perform well yet again.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
- All Researches
8
We explored the potential of intravenous silibinin, a milk thistle extract, in treating an HIV-HCV coinfected patient who didn't respond to standard therapy. After just two weeks of silibinin treatment, both HCV and HIV levels became undetectable.
While silibinin appeared promising, leading to a trend of increased CD4+ cells, the follow-up showed that HIV levels returned to their previous state after stopping additional therapy.
These findings suggest that while silibinin may help some, more research is needed to understand its benefits fully.
While silibinin appeared promising, leading to a trend of increased CD4+ cells, the follow-up showed that HIV levels returned to their previous state after stopping additional therapy.
These findings suggest that while silibinin may help some, more research is needed to understand its benefits fully.
Read More
8
We directly evaluated the effects of silymarin, or milk thistle extract, on hepatitis C virus (HCV) infection and liver protection.
Our study found that while silymarin does show some promise in reducing oxidative stress and inflammation, it didn't consistently surpass the potency of its individual flavonolignan compounds in battling the virus.
Overall, these findings indicate that silymarin-derived compounds could influence the progression of HCV in certain patients.
However, further research is needed to pinpoint clinical outcomes with standardized doses.
Our study found that while silymarin does show some promise in reducing oxidative stress and inflammation, it didn't consistently surpass the potency of its individual flavonolignan compounds in battling the virus.
Overall, these findings indicate that silymarin-derived compounds could influence the progression of HCV in certain patients.
However, further research is needed to pinpoint clinical outcomes with standardized doses.
Read More
4
We examined the use of silymarin, a popular herbal extract from milk thistle, among participants in the HALT-C Trial, focused on individuals with chronic hepatitis C. Our findings indicated that while many people were eager to utilize silymarin hoping to enhance treatment outcomes, there was no significant effect on liver enzyme levels or hepatitis C virus activity.
However, those taking silymarin reported fewer symptoms and somewhat better quality of life. Ultimately, since this study was observational, we believe more rigorous research is necessary to conclusively determine the benefits of silymarin for hepatitis C patients.
However, those taking silymarin reported fewer symptoms and somewhat better quality of life. Ultimately, since this study was observational, we believe more rigorous research is necessary to conclusively determine the benefits of silymarin for hepatitis C patients.
Read More
User Reviews
USERS' SCORE
Good
Based on 9 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective liver support
97 people found this helpful
One of the best liver drugs for both prevention and treatment! I occasionally purchase this product for my mother, who suffers from chronic viral hepatitis, as liver support is vital for her. Milk thistle ranks highly among hepatic herbs due to its efficacy. The bioactive compound silybin is not water-soluble, which hinders absorption. However, with phosphatidylcholine encapsulating silybin, its bioavailability for the liver is significantly enhanced, making it ten times more effective than pure silymarin. This results in better protection of liver cells, detoxification, stimulation of healthy cell growth, bile production, and reduced autoimmune reactions. My mother is pleased with the results, confirmed by analyses, taking it at night during optimal liver bioactivity.
Read More
9
Dermatitis relief
10 people found this helpful
Excellent composition! I bought it to support my liver, as I have had hepatitis B since childhood. The liver is the primary barrier against toxins. When overwhelmed, it fails to protect effectively, leading to various health issues, including dermatitis. After a month on ordinary milk thistle, I switched to these capsules, taking two daily before meals. Positive results take at least three months, but remarkably, my dermatitis has cleared for the first time in two years! I maintain a healthy lifestyle, avoiding alcohol. This milk thistle really worked wonders for me! Thank you for reading.
Read More
7.5
Liver health improving
10 people found this helpful
I have hepatitis C and take milk thistle capsules regularly. My liver feels better. The capsule size is convenient, and the ingredients are reliable. I take one capsule twice daily. I've tested this manufacturer's products multiple times, and I trust they will perform well yet again.
Read More
10
Hepatitis elimination
This product effectively eliminates hepatitis and can remove the hepatitis virus from the body.
Read More
9
Effective medicine
I bought this for my mother who has hepatitis B. It turns out that this milk thistle is a good treatment for hepatitis and remarkably effective.
Read More
Frequently Asked Questions
9
Dermatitis relief
10 people found this helpful
Excellent composition! I bought it to support my liver, as I have had hepatitis B since childhood. The liver is the primary barrier against toxins. When overwhelmed, it fails to protect effectively, leading to various health issues, including dermatitis. After a month on ordinary milk thistle, I switched to these capsules, taking two daily before meals. Positive results take at least three months, but remarkably, my dermatitis has cleared for the first time in two years! I maintain a healthy lifestyle, avoiding alcohol. This milk thistle really worked wonders for me! Thank you for reading.
7.5
Improved condition
After taking this, my hepatitis has improved significantly.
7.5
Liver health improving
10 people found this helpful
I have hepatitis C and take milk thistle capsules regularly. My liver feels better. The capsule size is convenient, and the ingredients are reliable. I take one capsule twice daily. I've tested this manufacturer's products multiple times, and I trust they will perform well yet again.
7.5
Liver function normal
This seems very effective for liver health. I have been consistently taking it since I acquired acute hepatitis and despite high liver function tests, my levels have returned to normal.
7.5
Effective treatment evidence
Milk thistle (silymarin) has proven efficacy. It helps prevent liver damage from anti-tuberculosis drugs, aids in lipid regulation, and is beneficial in non-alcoholic fatty liver disease, chemoradiotherapy-induced mucositis, chronic hepatitis B, diabetes, and chronic hepatitis C.
6
Stabilising toxins
Long-term use stabilises hepatitis B toxins and the ingredients are of high quality.
References
- Payer BA, Reiberger T, Rutter K, Beinhardt S, Staettermayer AF, et al. Successful HCV eradication and inhibition of HIV replication by intravenous silibinin in an HIV-HCV coinfected patient. J Clin Virol. 2010;49:131. 10.1016/j.jcv.2010.07.006
- Polyak SJ, Morishima C, Lohmann V, Pal S, Lee DY, et al. Identification of hepatoprotective flavonolignans from silymarin. Proc Natl Acad Sci U S A. 2010;107:5995. 10.1073/pnas.0914009107
- Seeff LB, Curto TM, Szabo G, Everson GT, Bonkovsky HL, et al. Herbal product use by persons enrolled in the hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial. Hepatology. 2008;47:605. PubMed
