Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 29 Researches
8.1
USERS' SCORE
Good
Based on 3 Reviews
8.8
Supplement Facts
Serving Size: One (1) Tablet
Amount Per Serving
%DV
Calories
0
Total Carbohydrate
<1 g
<1%+
Total Sugars
0 g
**
Incl. 0 g Added Sugars
0%+
Xylitol
<1 g
**
Lactobacillus rhamnosus GG
53 mg (10 billion CFUs)
**
Top Medical Research Studies
9
We explored how lactic acid bacteria (LAB) can combat the harmful effects of Candida albicans, the fungus responsible for yeast infections. Through our study, we found that the supernatant from LAB like Lactobacillus crispatus and L. gasseri effectively inhibited the growth and harmful activity of C. albicans.
Specifically, L. gasseri showed exceptional ability in preventing the formation of biofilms and hyphae, crucial stages in fungal development. Additionally, the metabolites produced by these bacteria downregulated key genes associated with C. albicans, reinforcing their role in maintaining vaginal health.
Overall, while the findings are promising, further research is needed to confirm the clinical effectiveness of these metabolites in treating or preventing yeast infections.
Specifically, L. gasseri showed exceptional ability in preventing the formation of biofilms and hyphae, crucial stages in fungal development. Additionally, the metabolites produced by these bacteria downregulated key genes associated with C. albicans, reinforcing their role in maintaining vaginal health.
Overall, while the findings are promising, further research is needed to confirm the clinical effectiveness of these metabolites in treating or preventing yeast infections.
Read More
8
We explored how Limosilactobacillus fermentum KBL674 impacts vaginal candidiasis, commonly caused by Candida albicans. In a mouse model, this probiotic strain significantly inhibited C. albicans growth and alleviated symptoms like tissue swelling and immune response. Interestingly, many of the administered L. fermentum KBL674 didn't remain in the gut; it altered gut bacteria diversity, linking these changes to reduced yeast infection severity. Overall, our findings suggest that L. fermentum KBL674 may offer a promising approach to help manage yeast infections.
Read More
8
We investigated how lactobacillus probiotics could restore the vaginal and gut microbiota of pregnant women dealing with vaginal candidiasis. In a well-structured randomized study with 78 participants, we compared a probiotic with a placebo over eight weeks.
Our findings showed that those receiving the probiotic had stable microbiota, unlike those on the placebo, who experienced significant shifts. This suggests lactobacillus can help maintain a healthy microbial balance, which is essential for health during pregnancy. Overall, lactobacillus probiotics offer promising benefits in managing yeast infections.
Our findings showed that those receiving the probiotic had stable microbiota, unlike those on the placebo, who experienced significant shifts. This suggests lactobacillus can help maintain a healthy microbial balance, which is essential for health during pregnancy. Overall, lactobacillus probiotics offer promising benefits in managing yeast infections.
Read More
Most Useful Reviews
10
Effective anti-yeast treatment
This product works wonders - a must when on antibiotics. All I can say is that it saved my behind, and I mean that literally. Last year, I ended up on antibiotics twice for over a month each time. The first time, I suffered during and for a couple of months after the course of Septra DS. My bowels felt awful and a yeast infection was taking its toll. I needed medication to resolve it. The second time I took Septra, I knew I needed three of these every day alongside a weaker option. It was like night and day. I had no issues whatsoever - no burning or pain, just regularity. Whenever my digestive tract isn't right, I take this again. It's a wonder pill, and I swear by it!
Read More
9.5
Helps prevent yeast infections
Recommended by a nurse, this product effectively keeps yeast infections at bay when using a prescription antibiotic. It works wonderfully!
Read More
9.5
Supports yeast infection recovery
This product was recommended to me by my doctor at Mayo Clinic as I will be taking several antibiotics for many months due to a serious disease. I believe it will help prevent oral thrush and yeast infections. I'm quite satisfied with this purchase and the price!
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 29 Researches
8.1
- All Researches
9.5
We investigated the potential of a specific strain of Lactobacillus gasseri, named VHProbi E09, to treat vaginitis and fight off common pathogens causing yeast infections. Through laboratory tests, we found that this strain effectively inhibited the growth of harmful bacteria and yeast by over 99%.
Additionally, it prevented these pathogens from adhering to vaginal cells, showing promise for future clinical applications. While these results are promising, further research is necessary to fully understand its effectiveness in clinical settings and its role in restoring normal vaginal flora.
Additionally, it prevented these pathogens from adhering to vaginal cells, showing promise for future clinical applications. While these results are promising, further research is necessary to fully understand its effectiveness in clinical settings and its role in restoring normal vaginal flora.
Read More
9.5
We investigated how Lactobacillus rhamnosus Lcr35, contained in the GYNOPHILUS product, can combat yeast infections like Candida. This study showed that the product’s formulation, enhanced by sodium thiosulfate, improves its ability to kill yeast cells.
Remarkably, after 48 hours of co-culturing, the yeast’s viability dropped to zero. The presence of odor-active sulfur compounds, specifically S-methyl thioacetate, was linked to this antifungal effect.
Interestingly, achieving the full antifungal impact relies on these sulfur components.
Remarkably, after 48 hours of co-culturing, the yeast’s viability dropped to zero. The presence of odor-active sulfur compounds, specifically S-methyl thioacetate, was linked to this antifungal effect.
Interestingly, achieving the full antifungal impact relies on these sulfur components.
Read More
9
We examined a new treatment, VAGINNE, derived from beneficial species to tackle vulvovaginal candidiasis (VVC). Using a mouse model, we observed that VAGINNE improved the balance of the vaginal microbiome while reducing harmful yeast growth.
Additionally, it lowered inflammatory markers in both vaginal tissue and blood, suggesting an anti-inflammatory effect. Our histological analysis showed better tissue integrity in treated mice compared to those without treatment.
These results indicate that VAGINNE can be a promising, side-effect-free alternative to conventional antifungals for managing VVC, especially in cases where drugs fail or cause issues.
Additionally, it lowered inflammatory markers in both vaginal tissue and blood, suggesting an anti-inflammatory effect. Our histological analysis showed better tissue integrity in treated mice compared to those without treatment.
These results indicate that VAGINNE can be a promising, side-effect-free alternative to conventional antifungals for managing VVC, especially in cases where drugs fail or cause issues.
Read More
9
We aimed to understand if adding probiotics to standard antifungal treatment improves outcomes for vulvovaginal candidiasis (VVC). In our study, 60 women diagnosed with VVC were divided into two groups.
One group received just antifungal medication, while the other received both antifungal and probiotic treatments.
Results indicated that those who took probiotics alongside their antifungal showed better improvement and had lower relapse rates. This suggests that probiotics can be a beneficial addition to standard yeast infection treatments.
One group received just antifungal medication, while the other received both antifungal and probiotic treatments.
Results indicated that those who took probiotics alongside their antifungal showed better improvement and had lower relapse rates. This suggests that probiotics can be a beneficial addition to standard yeast infection treatments.
Read More
9
We explored how lactic acid bacteria (LAB) can combat the harmful effects of Candida albicans, the fungus responsible for yeast infections. Through our study, we found that the supernatant from LAB like Lactobacillus crispatus and L. gasseri effectively inhibited the growth and harmful activity of C. albicans.
Specifically, L. gasseri showed exceptional ability in preventing the formation of biofilms and hyphae, crucial stages in fungal development. Additionally, the metabolites produced by these bacteria downregulated key genes associated with C. albicans, reinforcing their role in maintaining vaginal health.
Overall, while the findings are promising, further research is needed to confirm the clinical effectiveness of these metabolites in treating or preventing yeast infections.
Specifically, L. gasseri showed exceptional ability in preventing the formation of biofilms and hyphae, crucial stages in fungal development. Additionally, the metabolites produced by these bacteria downregulated key genes associated with C. albicans, reinforcing their role in maintaining vaginal health.
Overall, while the findings are promising, further research is needed to confirm the clinical effectiveness of these metabolites in treating or preventing yeast infections.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.8
- All Reviews
- Positive Reviews
- Negative Reviews
10
Effective anti-yeast treatment
This product works wonders - a must when on antibiotics. All I can say is that it saved my behind, and I mean that literally. Last year, I ended up on antibiotics twice for over a month each time. The first time, I suffered during and for a couple of months after the course of Septra DS. My bowels felt awful and a yeast infection was taking its toll. I needed medication to resolve it. The second time I took Septra, I knew I needed three of these every day alongside a weaker option. It was like night and day. I had no issues whatsoever - no burning or pain, just regularity. Whenever my digestive tract isn't right, I take this again. It's a wonder pill, and I swear by it!
Read More
9.5
Helps prevent yeast infections
Recommended by a nurse, this product effectively keeps yeast infections at bay when using a prescription antibiotic. It works wonderfully!
Read More
9.5
Supports yeast infection recovery
This product was recommended to me by my doctor at Mayo Clinic as I will be taking several antibiotics for many months due to a serious disease. I believe it will help prevent oral thrush and yeast infections. I'm quite satisfied with this purchase and the price!
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Nachum Z, Suleiman A, Colodner R, Battino S, Wattad M, et al. Oral Probiotics to Prevent Recurrent Vulvovaginal Infections During Pregnancy-Multicenter Double-Blind, Randomized, Placebo-Controlled Trial. Nutrients. 2025;17. doi:10.3390/nu17030460
- Horng HC, Xu JW, Kuo YS, Chen YS, Chiu YH, et al. Dual Mechanisms of Action: Anti-Candida and Anti-Inflammatory Potential of Fermentation Broth in Treating Vulvovaginal Candidiasis. J Fungi (Basel). 2024;11. doi:10.3390/jof11010018
- Thekho AJ, Mendiratta V, Garg T, Kaur R, Yadav V. Role of Probiotic in Vulvovaginal Candidiasis: A Randomised Controlled Non-blinded Trial from India. Indian J Dermatol. 2024;69:422. doi:10.4103/ijd.ijd_193_24
- Bae WY, Lee YJ, Jo S, Shin SL, Kim TR, et al. Effects of LM1215 on and . Yonsei Med J. 2024;65:727. doi:10.3349/ymj.2023.0490
- Jang SJ, Jo EJ, Lee C, Cho BR, Shin YJ, et al. Limosilactobacillus fermentum KBL674 Alleviates Vaginal Candidiasis. Probiotics Antimicrob Proteins. 2024. doi:10.1007/s12602-024-10403-3
- Vazquez-Munoz R, Thompson A, Sobue T, Dongari-Bagtzoglou A. is a dominant in the murine oral mucosa and has chitinase activity that compromises fungal cell wall integrity. mBio. 2024;15:e0241624. doi:10.1128/mbio.02416-24
- Zhang J, Li K, Cao T, Duan Z. Characterization of a Lactobacillus gasseri strain as a probiotic for female vaginitis. Sci Rep. 2024;14:14426. doi:10.1038/s41598-024-65550-y
- Elsayes SA, El Attar MS, ElHadary A, Aboulela AG, Essawy MM, et al. Antimycotic prophylaxis with multispecies probiotics against oral candidiasis in new complete denture wearers: A randomized clinical trial. J Prosthet Dent. 2024. doi:10.1016/j.prosdent.2024.05.018
- Zahedifard T, Khadivzadeh T, Rakhshkhorshid M. The Role of Probiotics in the Treatment of Vulvovaginal Candidiasis: A Systematic Review and Meta-Analysis. Ethiop J Health Sci. 2023;33:881. doi:10.4314/ejhs.v33i5.18
- Sookkhee S, Khamnoi P, Sastraruji T, Boonkum S, Wikan N, et al. Synergistic Inhibition of Synbiotic Cultures among Lactobacilli and Plant Extracts against Vaginal Discharge Causing . Nutrients. 2024;16. doi:10.3390/nu16091372
- Ang XY, Roslan NS, Ahmad N, Yusof SM, Abdullah N, et al. Lactobacillus probiotics restore vaginal and gut microbiota of pregnant women with vaginal candidiasis. Benef Microbes. 2023;14:421. doi:10.1163/18762891-20220103
- Bertarello C, Savio D, Morelli L, Bouzalov S, Davidova D, et al. Efficacy and safety of Lactobacillus plantarum P 17630 strain soft vaginal capsule in vaginal candidiasis: a randomized non-inferiority clinical trial. Eur Rev Med Pharmacol Sci. 2024;28:384. doi:10.26355/eurrev_202401_34927
- Faustino M, Pereira JO, Pereira AM, Oliveira AS, Ferreira CMH, et al. Vaginal prevention of Candida albicans: synergistic effect of lactobacilli and mannan oligosaccharides (MOS). Appl Microbiol Biotechnol. 2024;108:73. doi:10.1007/s00253-023-12909-2
- Das S, Konwar BK. Inhibiting pathogenicity of vaginal Candida albicans by lactic acid bacteria and MS analysis of their extracellular compounds. APMIS. 2024;132:161. doi:10.1111/apm.13365
- Deshkar S, Yeole P, Mahore J, Shinde A, Giram P. Polyelectrolyte-Complex-Based Hydrogel Inserts for Vaginal Delivery of Posaconazole and Probiotics. Gels. 2023;9. doi:10.3390/gels9110851
- ElFeky DS, Awad AR, Shamseldeen AM, Mowafy HL, Hosny SA. Comparing the therapeutic potentials of vs. against vulvovaginal candidiasis in female rats: an study. Front Microbiol. 2023;14:1222503. doi:10.3389/fmicb.2023.1222503
- Chantanawilas P, Pahumunto N, Thananimit S, Teanpaisan R. Anticandidal Activity of Various Probiotic Lactobacillus Strains and Their Efficacy Enhanced by Prebiotic Supplementation. Curr Microbiol. 2024;81:271. doi:10.1007/s00284-024-03800-y
- Pimentel MMNSC, de Carvalho Alves J, Pinheiro LHS, Roselino MN. Potential Action of Probiotics Against Fungi of the Genus : A Bibliographic Review. Recent Pat Biotechnol. 2023;17:198. doi:10.2174/1872208317666221027093644
- Spaggiari L, Sala A, Ardizzoni A, De Seta F, Singh DK, et al. Lactobacillus acidophilus, L. plantarum, L. rhamnosus, and L. reuteri Cell-Free Supernatants Inhibit Candida parapsilosis Pathogenic Potential upon Infection of Vaginal Epithelial Cells Monolayer and in a Transwell Coculture System . Microbiol Spectr. 2022;10:e0269621. doi:10.1128/spectrum.02696-21
- Dausset C, Bornes S, Miquel S, Kondjoyan N, Angenieux M, et al. Identification of sulfur components enhancing the anti-Candida effect of Lactobacillus rhamnosus Lcr35. Sci Rep. 2020;10:17074. doi:10.1038/s41598-020-74027-7
- Kumherová M, Veselá K, Kosová M, Mašata J, Horáčková Š, et al. Novel Potential Probiotic Lactobacilli for Prevention and Treatment of Vulvovaginal Infections. Probiotics Antimicrob Proteins. 2021;13:163. doi:10.1007/s12602-020-09675-2
- Poupet C, Saraoui T, Veisseire P, Bonnet M, Dausset C, et al. Lactobacillus rhamnosus Lcr35 as an effective treatment for preventing Candida albicans infection in the invertebrate model Caenorhabditis elegans: First mechanistic insights. PLoS One. 2019;14:e0216184. doi:10.1371/journal.pone.0216184
- Lee X, Vergara C, Lozano CP. Severity of Candida-associated denture stomatitis is improved in institutionalized elders who consume Lactobacillus rhamnosus SP1. Aust Dent J. 2019;64:229. doi:10.1111/adj.12692
- De Gregorio PR, Silva JA, Marchesi A, Nader-Macías MEF. Anti-Candida activity of beneficial vaginal lactobacilli in in vitro assays and in a murine experimental model. FEMS Yeast Res. 2019;19. doi:10.1093/femsyr/foz008
- Leão MVP, Tavares TAA, Gonçalves E Silva CR, Dos Santos SSF, Junqueira JC, et al. Lactobacillus rhamnosus intake can prevent the development of Candidiasis. Clin Oral Investig. 2018;22:2511. doi:10.1007/s00784-018-2347-8
- Rossoni RD, Dos Santos Velloso M, Figueiredo LMA, Martins CP, Jorge AOC, et al. Clinical strains of Lactobacillus reduce the filamentation of Candida albicans and protect Galleria mellonella against experimental candidiasis. Folia Microbiol (Praha). 2018;63:307. doi:10.1007/s12223-017-0569-9
- Tan Y, Leonhard M, Moser D, Ma S, Schneider-Stickler B. Inhibitory effect of probiotic lactobacilli supernatants on single and mixed non-albicans Candida species biofilm. Arch Oral Biol. 2018;85:40. doi:10.1016/j.archoralbio.2017.10.002
- Mailänder-Sánchez D, Braunsdorf C, Grumaz C, Müller C, Lorenz S, et al. Antifungal defense of probiotic Lactobacillus rhamnosus GG is mediated by blocking adhesion and nutrient depletion. PLoS One. 2017;12:e0184438. doi:10.1371/journal.pone.0184438
- de Oliveira FE, Rossoni RD, de Barros PP, Begnini BE, Junqueira JC, et al. Immunomodulatory effects and anti-Candida activity of lactobacilli in macrophages and in invertebrate model of Galleria mellonella. Microb Pathog. 2017;110:603. doi:10.1016/j.micpath.2017.08.006
