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SCIENTIFIC SCORE
Questionable
Based on 11 Researches
6.6
USERS' SCORE
Good
Based on 254 Reviews
8.9
Supplement Facts
Serving Size: 3 Veg Capsules
Amount Per Serving
%DV
Magnesium (elemental) (from 2,667 mg Magnesium Citrate)
400 mg
95%
Top Medical Research Studies
4
Effectiveness of magnesium on constipation
Effect of reduced daily magnesium oxide doses on laxative effect: a single-center retrospective study.
Study directly addresses magnesium use
We explored how changing the frequency of magnesium oxide (MgO) doses influences its effectiveness in relieving constipation. In this study, we looked at 11 patients who had been regularly using MgO to manage their bowel movements and decided to reduce their daily dose frequency over two weeks.
Initially, patients were taking magnesium three times a day, but we reduced this to either two or one dose per day while keeping the total amount the same. We found that the average number of bowel movements dropped from 7.6 to 6.6 in this period. However, this change wasn't statistically significant, indicating that it may not be clinically meaningful.
Additionally, we measured stool consistency using the Bristol Stool Form Scale and noted no significant difference before and after the dosage adjustment. Our findings suggest that reducing the number of doses does not impact the laxative effect of magnesium oxide. This implies that patients can comfortably manage their magnesium intake without sacrificing effectiveness.
Initially, patients were taking magnesium three times a day, but we reduced this to either two or one dose per day while keeping the total amount the same. We found that the average number of bowel movements dropped from 7.6 to 6.6 in this period. However, this change wasn't statistically significant, indicating that it may not be clinically meaningful.
Additionally, we measured stool consistency using the Bristol Stool Form Scale and noted no significant difference before and after the dosage adjustment. Our findings suggest that reducing the number of doses does not impact the laxative effect of magnesium oxide. This implies that patients can comfortably manage their magnesium intake without sacrificing effectiveness.
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9
Magnesium effectively aids constipation
The effect of food, vitamin, or mineral supplements on chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials.
Direct assessment of magnesium's effect
We investigated how magnesium supplements affect chronic constipation through a systematic review of randomized controlled trials. The analysis included eight studies with a total of 787 participants. We focused on magnesium oxide among other treatment options and assessed its effectiveness in increasing stool frequency and improving consistency.
The findings were quite promising for magnesium oxide. Our results showed that participants who took magnesium experienced a boost in bowel movements, with an average increase of about 3.7 additional movements per week. This improvement in stool consistency was also noteworthy, scoring higher on the Bristol stool chart.
While other supplements like senna and kiwifruit were explored, they didn't significantly enhance symptoms of constipation in this analysis. Therefore, we suggest that magnesium oxide stands out in this study as a worthwhile option for managing chronic constipation. But it’s essential to remember that further research could help confirm these findings and explore the effects of whole food alternatives.
The findings were quite promising for magnesium oxide. Our results showed that participants who took magnesium experienced a boost in bowel movements, with an average increase of about 3.7 additional movements per week. This improvement in stool consistency was also noteworthy, scoring higher on the Bristol stool chart.
While other supplements like senna and kiwifruit were explored, they didn't significantly enhance symptoms of constipation in this analysis. Therefore, we suggest that magnesium oxide stands out in this study as a worthwhile option for managing chronic constipation. But it’s essential to remember that further research could help confirm these findings and explore the effects of whole food alternatives.
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5
MgO Treatment During Pregnancy
No association between major congenital malformations and exposure to Kampo medicines containing rhubarb rhizome: A Japanese database study.
Study assesses magnesium's effects
We explored the safety of magnesium oxide (MgO) as a treatment for constipation during pregnancy, particularly in comparison to Kampo medicines containing rhubarb rhizome. In this study, we analyzed a large database of Japanese health insurance claims, focusing on pregnant women who were prescribed either MgO or Kampo medicines in the first trimester.
Among the 75,398 infants examined, we found that about 6% were diagnosed with major congenital malformations (MCMs) within their first year. From the data, there were 9,852 infants born to women prescribed MgO, with 6.9% having MCMs, while for those prescribed Kampo medicines, 6.2% reported MCMs.
The statistical analysis showed no significant difference in the risks of MCMs between infants whose mothers took MgO and those who used Kampo medicines. Essentially, we did not find any strong evidence suggesting that magnesium treatment for constipation has a greater risk of leading to congenital malformations compared to Kampo medicines. Therefore, this study provides important reassurance about the safety of using magnesium during early pregnancy.
Among the 75,398 infants examined, we found that about 6% were diagnosed with major congenital malformations (MCMs) within their first year. From the data, there were 9,852 infants born to women prescribed MgO, with 6.9% having MCMs, while for those prescribed Kampo medicines, 6.2% reported MCMs.
The statistical analysis showed no significant difference in the risks of MCMs between infants whose mothers took MgO and those who used Kampo medicines. Essentially, we did not find any strong evidence suggesting that magnesium treatment for constipation has a greater risk of leading to congenital malformations compared to Kampo medicines. Therefore, this study provides important reassurance about the safety of using magnesium during early pregnancy.
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Most Useful Reviews
9.5
Enhanced serenity
Calmness, only calmness. After a few weeks on 400 mg of magnesium daily, my psychosis improved. I observed various deficiency symptoms such as insomnia and cramps. I consulted an endocrinologist who confirmed my magnesium deficiency. Now, I feel much calmer and can communicate better with my child, resulting in happiness for both of us.
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9.5
Effective stool softener
Magnesium citrate is more effective for stool softening and calming than magnesium glycinate. I take it regularly, and it helps with constipation while promoting relaxation. I recommend it—just one tablet before bed works wonders!
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9.5
Restful sleep
I’ve been wanting to order magnesium for ages. Using it before bed, I was shocked to find I started getting enough sleep. I now wake up feeling refreshed and energetic, and it helps with my constipation too. I recommend it!
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Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 11 Researches
6.6
9
Magnesium aids constipation, boosts brain
Defecation after magnesium supplementation enhances cognitive performance in triathletes.
Moderate relevance to magnesium effects
We explored the relationship between magnesium supplementation, defecation, and cognitive performance in elite triathletes. In a carefully designed crossover trial, participants undertook cognitive tests after taking magnesium oxide and after defecation. This study highlighted an interesting potential connection between the state of our digestive system and cognitive abilities.
We found that after magnesium-induced defecation, participants completed cognitive tasks more quickly compared to when they had not defecated. Specifically, the average completion time for the cognitive test dropped significantly after defecation when magnesium was involved. While this suggests that magnesium can aid in relieving constipation, its role in improving overall cognitive function during athletics is also noteworthy.
Although we observed an increase in cognitive performance following magnesium supplementation, it’s important to note that no significant changes in blood flow or oxygen levels were detected in the brain during the test. Instead, we noted decreased oxygen levels in the digestive region, hinting at an increased demand for energy there.
Overall, our findings suggest a potential new avenue for enhancing cognitive function in athletes through magnesium to improve constipation. However, the direct effects of magnesium solely on constipation require further investigation.
We found that after magnesium-induced defecation, participants completed cognitive tasks more quickly compared to when they had not defecated. Specifically, the average completion time for the cognitive test dropped significantly after defecation when magnesium was involved. While this suggests that magnesium can aid in relieving constipation, its role in improving overall cognitive function during athletics is also noteworthy.
Although we observed an increase in cognitive performance following magnesium supplementation, it’s important to note that no significant changes in blood flow or oxygen levels were detected in the brain during the test. Instead, we noted decreased oxygen levels in the digestive region, hinting at an increased demand for energy there.
Overall, our findings suggest a potential new avenue for enhancing cognitive function in athletes through magnesium to improve constipation. However, the direct effects of magnesium solely on constipation require further investigation.
Read More
9
Magnesium effectively aids constipation
The effect of food, vitamin, or mineral supplements on chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials.
Direct assessment of magnesium's effect
We investigated how magnesium supplements affect chronic constipation through a systematic review of randomized controlled trials. The analysis included eight studies with a total of 787 participants. We focused on magnesium oxide among other treatment options and assessed its effectiveness in increasing stool frequency and improving consistency.
The findings were quite promising for magnesium oxide. Our results showed that participants who took magnesium experienced a boost in bowel movements, with an average increase of about 3.7 additional movements per week. This improvement in stool consistency was also noteworthy, scoring higher on the Bristol stool chart.
While other supplements like senna and kiwifruit were explored, they didn't significantly enhance symptoms of constipation in this analysis. Therefore, we suggest that magnesium oxide stands out in this study as a worthwhile option for managing chronic constipation. But it’s essential to remember that further research could help confirm these findings and explore the effects of whole food alternatives.
The findings were quite promising for magnesium oxide. Our results showed that participants who took magnesium experienced a boost in bowel movements, with an average increase of about 3.7 additional movements per week. This improvement in stool consistency was also noteworthy, scoring higher on the Bristol stool chart.
While other supplements like senna and kiwifruit were explored, they didn't significantly enhance symptoms of constipation in this analysis. Therefore, we suggest that magnesium oxide stands out in this study as a worthwhile option for managing chronic constipation. But it’s essential to remember that further research could help confirm these findings and explore the effects of whole food alternatives.
Read More
9
Magnesium aids cancer patient care
Oral application of magnesium-L-threonate enhances analgesia and reduces the dosage of opioids needed in advanced cancer patients-A randomized, double-blind, placebo-controlled trial.
Addresses magnesium's role in constipation
We conducted a randomized, double-blind trial to assess how magnesium-L-threonate, a new compound, might help relieve constipation while enhancing the pain relief effects of opioids in patients with advanced cancer. During the study, patients receiving this treatment were compared with those taking a placebo, allowing us to clearly see the differences in outcomes.
As the trial progressed, we noticed significant improvements in the group taking magnesium-L-threonate. Notably, this treatment not only helped in managing pain more effectively but also significantly alleviated opioid-induced constipation—a common side effect of opioid use. The data indicated that patients on magnesium-L-threonate required lower doses of opioids for pain management while enjoying better gastrointestinal comfort.
Overall, our findings suggest that magnesium-L-threonate is a promising option in the palliative care landscape for cancer patients, addressing both pain relief and constipation, which can greatly enhance their quality of life.
As the trial progressed, we noticed significant improvements in the group taking magnesium-L-threonate. Notably, this treatment not only helped in managing pain more effectively but also significantly alleviated opioid-induced constipation—a common side effect of opioid use. The data indicated that patients on magnesium-L-threonate required lower doses of opioids for pain management while enjoying better gastrointestinal comfort.
Overall, our findings suggest that magnesium-L-threonate is a promising option in the palliative care landscape for cancer patients, addressing both pain relief and constipation, which can greatly enhance their quality of life.
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8
Magnesium's role in constipation treatment
Effect of magnesium oxide with probiotics on bowel movements in elderly orthopedic patients with chronic constipation: a retrospective chart review.
Magnesium's effects on constipation evaluated
We aimed to understand how magnesium, particularly when combined with probiotics, influences bowel movements in elderly orthopedic patients suffering from chronic constipation. A retrospective chart review allowed us to analyze various patient records, focusing specifically on the treatments they received and the outcomes.
Magnesium is often talked about as a potential remedy for constipation because it can help draw water into the intestines, making it easier to pass stools. However, since our study also involved probiotics, which can also impact gut health, it becomes harder to isolate the specific effects of magnesium alone.
After reviewing the data, we observed that the combination of magnesium and probiotics did not show a significant advantage in improving bowel movements for the patients involved. This indicates that while magnesium may play a supportive role, its effectiveness on constipation could vary depending on individual circumstances and may not be as pronounced when combined with other treatments.
Overall, this study serves as a reminder of the complexity of managing constipation, especially in the elderly population, where multiple factors can come into play.
Magnesium is often talked about as a potential remedy for constipation because it can help draw water into the intestines, making it easier to pass stools. However, since our study also involved probiotics, which can also impact gut health, it becomes harder to isolate the specific effects of magnesium alone.
After reviewing the data, we observed that the combination of magnesium and probiotics did not show a significant advantage in improving bowel movements for the patients involved. This indicates that while magnesium may play a supportive role, its effectiveness on constipation could vary depending on individual circumstances and may not be as pronounced when combined with other treatments.
Overall, this study serves as a reminder of the complexity of managing constipation, especially in the elderly population, where multiple factors can come into play.
Read More
7
Magnesium aids constipation relief
Coadministration of Lactulose with Probiotics Ameliorates Loperamide-Induced Constipation in Mice.
Evaluates magnesium's role in constipation
We investigated how well magnesium, when combined with lactulose and probiotics, helps relieve constipation in mice. To do this, we induced constipation using loperamide and closely monitored various factors like stool number, water content, and gastrointestinal transit time.
Our findings indicated that using magnesium alongside lactulose improved fecal characteristics significantly. This combination also enhanced the production of short-chain fatty acids, which are beneficial for gut health. While magnesium’s individual effect isn’t isolated in our study, it showed promising results as part of a broader treatment strategy for constipation.
Overall, our research supports the idea that magnesium can play a supportive role when combined with other treatments, possibly leading to more effective management of constipation.
Our findings indicated that using magnesium alongside lactulose improved fecal characteristics significantly. This combination also enhanced the production of short-chain fatty acids, which are beneficial for gut health. While magnesium’s individual effect isn’t isolated in our study, it showed promising results as part of a broader treatment strategy for constipation.
Overall, our research supports the idea that magnesium can play a supportive role when combined with other treatments, possibly leading to more effective management of constipation.
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User Reviews
USERS' SCORE
Good
Based on 254 Reviews
8.9
10
Constipation relief
Magnesium citrate has been my salvation for years of intestinal problems and constipation. Despite trying numerous remedies and consulting various doctors, nothing worked. After taking 4 capsules daily—2 with meals and 2 before bed—the results have been fantastic. It’s convenient having small capsules that are easy to swallow. I’m very satisfied with this product and will reorder.
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10
Constipation relief
After regularly taking medication for severe constipation, I found magnesium citrate to be effective, and I’m grateful to no longer need the hospital. I will continue its use for additional health benefits.
10
Excellent product
This product has benefited me greatly. It helped me sleep, alleviated my bone pain, and addressed my constipation issues. I highly recommend it; the Now Food brand is fantastic.
10
Helps with constipation
I've been taking this magnesium for over a year. It has virtually eliminated my constipation and decreased my headaches.
10
Effective relief
I tried various methods for constipation relief without success, but magnesium proved effective. I wonder if taking magnesium makes it harder to gain weight.
