Overview

SCIENTIFIC SCORE
Questionable
Based on 12 Researches
6.1
USERS' SCORE
Good
Based on 73 Reviews
8.9
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Vitamin C (from culture of S. cerevisiae)
25 mg
28%
Folate (from culture of S. cerevisiae)
400 mcg DFE
100%
Vitamin B12 (as Methylcobalamin from culture of S. cerevisiae)
500 mcg 
20833%
Iron (from Brown Rice Chelate)
22 mg 
122%
RAW Organic Fruit & Vegetable BlendOrganic Apple (fruit), Organic Beet (root), Organic Broccoli (stalk & flower), Organic Carrot (root), Organic Spinach (leaf), Organic Tomato (fruit), Organic Strawberry (fruit), Organic Tart Cherry (fruit), Organic Blackberry (fruit), Organic Green Bell Pepper (fruit), Organic Brussels Sprout (leaf), Organic Blueberry (fruit), Organic Ginger (root), Organic Garlic (bulb), Organic Green Onion (bulb), Organic Raspberry (fruit), Organic Parsley (leaf), Organic Cauliflower (flower & stem), Organic Red Cabbage (leaf), Organic Kale (leaf), Organic Cucumber (gourd), Organic Celery (stalk), Organic Asparagus Juice (flower & stem)
310 mg
+
RAW Probiotic & Enzyme BlendLipase, Protease, Aspergillopepsin, beta-Glucanase, Cellulase, Bromelain, Phytase, Lactase, Papain, Peptidase, Pectinase, Hemicellulase, Xylanase, [Lactobacillus plantarum, Lactobacillus bulgaricus] (500 Million CFU)
60 mg
+

Top Medical Research Studies

We assessed how iron supplementation impacts blood donors who may suffer from low iron levels. Our analysis included thirty studies with nearly 4,700 participants, focusing on the differences between those receiving iron and those who didn’t.

We found that iron supplements reduced the chances of donors being deferred due to low hemoglobin levels and helped elevate their hemoglobin and iron stores. However, we also noted more side effects, like constipation and nausea, among those taking iron.

These side effects hinder its widespread use, suggesting iron supplements should be targeted to at-risk individuals only.
Read More
8
Infant formula impacts stool consistency
We evaluated how different infant formulas affect the stool characteristics of infants. Two clinical studies focused on infants transitioning from exclusive breastfeeding to formula feeding and those already on formula.

Parents recorded each infant's feeding tolerance, spit-up occurrences, and stool characteristics during the trials. Our findings revealed that the composition of the formula impacts stool consistency.

Specifically, infants consuming formula A exhibited softer stools and more frequent bowel movements compared to those on formula B, which may help lessen concerns about constipation associated with iron-fortified options.
Read More
5
Constipation prevalence linked to iron
We investigated the prevalence and contributing factors of constipation among healthy pregnant women over the course of their pregnancy. Our longitudinal study showed that constipation affects about 24% of women during various stages of pregnancy and even postpartum.

Notably, we found that iron supplementation was linked to a higher risk of constipation. This means that while iron is an important nutrient during pregnancy, it may also contribute to discomfort for some women.

These findings highlight the importance of monitoring bowel health as part of prenatal care.
Read More

Most Useful Reviews

10
Aiding anemia
111 people found this helpful
These pills truly work! They have significantly improved my anemia, as my recent blood test numbers show improvement. I still experience coldness, but my doctor confirms my numbers are getting better. I've just started my second bottle, and best of all, there is NO CONSTIPATION whatsoever!
Read More
10
No constipation
31 people found this helpful
The raw iron room is excellent as it contains no synthetic materials, preventing constipation. Additionally, it includes cofactors that enhance iron absorption and remains in easily digestible forms.
Read More
10
Fast acting supplement.
21 people found this helpful
Great iron supplement!!! Fast acting. After being told by a medical professional that I was severely anaemic, I researched the best type of iron to take. I found this brand because I sought raw iron with natural ingredients. I've experienced a tremendous difference in mood, energy, and overall health, which I put down to these iron supplements, as it was the only change I made. Importantly, they're non-constipating; I noted that most iron supplements warn of constipation. I'm extremely pleased with this product and highly recommend it.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 12 Researches
6.1
  • All Researches
We assessed how iron supplementation impacts blood donors who may suffer from low iron levels. Our analysis included thirty studies with nearly 4,700 participants, focusing on the differences between those receiving iron and those who didn’t.

We found that iron supplements reduced the chances of donors being deferred due to low hemoglobin levels and helped elevate their hemoglobin and iron stores. However, we also noted more side effects, like constipation and nausea, among those taking iron.

These side effects hinder its widespread use, suggesting iron supplements should be targeted to at-risk individuals only.
Read More
8
Iron deficiency linked to constipation
This study examined the connection between gastrointestinal issues, particularly constipation, and depression in patients with iron deficiency anemia (IDA).

Conducted at Trakya University, the case-control study involved 125 IDA patients and 57 healthy individuals.

We found that IDA patients reported constipation significantly more often than the control group, with 56% experiencing this symptom. Additionally, their self-reported intensity of bloating and dyspepsia was notably higher, indicating a clear link between IDA, gastrointestinal discomfort, and potential mental health challenges.
Read More
8
Infant formula impacts stool consistency
We evaluated how different infant formulas affect the stool characteristics of infants. Two clinical studies focused on infants transitioning from exclusive breastfeeding to formula feeding and those already on formula.

Parents recorded each infant's feeding tolerance, spit-up occurrences, and stool characteristics during the trials. Our findings revealed that the composition of the formula impacts stool consistency.

Specifically, infants consuming formula A exhibited softer stools and more frequent bowel movements compared to those on formula B, which may help lessen concerns about constipation associated with iron-fortified options.
Read More
7
Iron's minimal effect on constipation
We explored the effects of low-dose iron supplementation on gastrointestinal complaints, particularly constipation, in pregnant women. Conducting two randomized studies, we aimed to determine how different forms of iron—ferrous fumarate, ferrous bisglycinate, and ferrous sulphate—would affect the frequency of GI issues among healthy women throughout their pregnancy.

Through our investigations, we found that constipation was only significantly associated with higher doses of ferrous fumarate (80 mg/day). Interestingly, women taking lower doses of ferrous fumarate (20-60 mg/day) did not report more GI side effects, indicating that manageable doses of iron may be tolerated without significant worry about constipation.

Among the iron formulas tested, ferrous bisglycinate at 25 mg showed the best profile, resulting in fewer GI complaints overall compared to the others. In fact, it was linked to a lower incidence of black stools, which can often be associated with iron intake. Ultimately, we observed that while low-dose iron supplementation might incur some side effects, they are generally not severe enough to warrant a change in dosage or interruption of treatment.
Read More
We carefully looked at the impact of lactoferrin (Lf) on treating iron deficiency anemia (IDA) in children, especially focusing on its connection to constipation. In an extensive review of 11 studies, including 10 randomized controlled trials, we saw promising results where children receiving Lf showed notable improvements in their hemoglobin and serum ferritin levels compared to those who only received iron or a placebo.

Interestingly, we found that while some adverse effects like constipation, vomiting, and abdominal pain were reported, those treated with Lf experienced a significant decrease in constipation. This suggests that Lf not only helps in boosting iron levels but may also be easier on the digestive system than traditional iron supplements.

Overall, our exploration indicates that incorporating lactoferrin in the treatment of IDA in children not only helps address anemia effectively but also might provide a gentler alternative for the gut. Users considering iron supplements for their children might find lactoferrin to be a beneficial option.
Read More

User Reviews

USERS' SCORE
Good
Based on 73 Reviews
8.9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Aiding anemia
111 people found this helpful
These pills truly work! They have significantly improved my anemia, as my recent blood test numbers show improvement. I still experience coldness, but my doctor confirms my numbers are getting better. I've just started my second bottle, and best of all, there is NO CONSTIPATION whatsoever!
Read More
10
No constipation
31 people found this helpful
The raw iron room is excellent as it contains no synthetic materials, preventing constipation. Additionally, it includes cofactors that enhance iron absorption and remains in easily digestible forms.
Read More
10
Fast acting supplement.
21 people found this helpful
Great iron supplement!!! Fast acting. After being told by a medical professional that I was severely anaemic, I researched the best type of iron to take. I found this brand because I sought raw iron with natural ingredients. I've experienced a tremendous difference in mood, energy, and overall health, which I put down to these iron supplements, as it was the only change I made. Importantly, they're non-constipating; I noted that most iron supplements warn of constipation. I'm extremely pleased with this product and highly recommend it.
Read More
10
No stomach pain
8 people found this helpful
I switched to this supplement as it doesn’t cause stomach pain or constipation like many others. It contains vitamin C to assist with iron absorption, although the iron content is a bit low for severe deficiencies.
Read More
10
Improved symptoms
7 people found this helpful
I’ve been taking this for about 10 days and have noticed improvements in my energy levels, shortness of breath, and complexion. Importantly, I haven't experienced any constipation, and I feel my body is absorbing the iron well.
Read More

Frequently Asked Questions

10
Improved symptoms
7 people found this helpful
I’ve been taking this for about 10 days and have noticed improvements in my energy levels, shortness of breath, and complexion. Importantly, I haven't experienced any constipation, and I feel my body is absorbing the iron well.
9
Reduced constipation
4 people found this helpful
Good. Initially, my iron deficiency anaemia was problematic. I experienced severe menstrual symptoms, including headaches and nausea. I thought I felt weak, but it turned out to be related to my iron levels, as I had constipation issues. However, after starting on iron supplements, my menstrual symptoms improved significantly, and I no longer experience constipation. It’s easy to take just one capsule a day.
10
No gastrointestinal discomfort
6 people found this helpful
This brand consistently delivers quality, and their iron supplement does not cause gastrointestinal discomfort or constipation. It effectively increases iron levels and has a balanced composition in terms of its cofactors.
0
Super constipated
4 people found this helpful
This product makes me extremely constipated and had no effect on my iron levels in blood tests.
9
Less fatigue
3 people found this helpful
After being diagnosed with anaemia, I tried this supplement and found that it lessened my fatigue during my periods, without causing the constipation typically experienced with prescribed iron.
9
No constipation
3 people found this helpful
This is far better than the iron from pharmacies that always causes constipation. This natural iron has worked wonders for me.
9
Improved breathing
2 people found this helpful
I've had low blood cell counts and difficulty breathing. Taking this after lunch has helped, and I've experienced no constipation, even with my digestive issues. This product is fantastic; I also take RAW probiotics and enzymes.
10
No constipation benefits
4 people found this helpful
This iron supplement has been wonderful as it hasn’t upset my stomach or caused constipation, unlike previous ones. It works well with other vitamins and is effective for my iron needs.
7.5
Supports without issues
2 people found this helpful
If you struggle with standard iron absorption, try this. It supported my ferritin and haemoglobin during pregnancy without causing constipation as other medications have. Iron is a complex supplement, but I recommend starting with this one and monitoring your tests.
4
Iron supplementation effects on constipation
We examined how different types of iron supplementation affect pregnant women, particularly focusing on potential constipation as a side effect. In a systematic review and meta-analysis, we gathered data from 26 studies involving nearly 4,400 participants to compare daily and intermittent iron supplementation.

Interestingly, we found that daily oral iron supplementation was associated with a higher occurrence of constipation compared to intermittent supplementation. The adjusted odds ratio for constipation was 1.95, indicating a nearly two-fold increase in risk for those taking daily iron. However, our analysis revealed that both daily and intermittent iron supplements could increase hemoglobin levels effectively, showing no significant difference in overall efficacy.

Ultimately, while daily iron supplementation led to better ferritin levels, women experienced more adverse effects such as nausea, diarrhea, and constipation. This suggests that intermittent iron supplementation could be a more favorable option, especially for those who are sensitive to the side effects associated with daily doses.
We carefully looked at the impact of lactoferrin (Lf) on treating iron deficiency anemia (IDA) in children, especially focusing on its connection to constipation. In an extensive review of 11 studies, including 10 randomized controlled trials, we saw promising results where children receiving Lf showed notable improvements in their hemoglobin and serum ferritin levels compared to those who only received iron or a placebo.

Interestingly, we found that while some adverse effects like constipation, vomiting, and abdominal pain were reported, those treated with Lf experienced a significant decrease in constipation. This suggests that Lf not only helps in boosting iron levels but may also be easier on the digestive system than traditional iron supplements.

Overall, our exploration indicates that incorporating lactoferrin in the treatment of IDA in children not only helps address anemia effectively but also might provide a gentler alternative for the gut. Users considering iron supplements for their children might find lactoferrin to be a beneficial option.
5
Constipation prevalence linked to iron
We investigated the prevalence and contributing factors of constipation among healthy pregnant women over the course of their pregnancy. Our longitudinal study showed that constipation affects about 24% of women during various stages of pregnancy and even postpartum.

Notably, we found that iron supplementation was linked to a higher risk of constipation. This means that while iron is an important nutrient during pregnancy, it may also contribute to discomfort for some women.

These findings highlight the importance of monitoring bowel health as part of prenatal care.
2
Iron treatment does not worsen constipation
We examined how sucroferric oxyhydroxide (SFOH), an iron-based phosphate binder, affects gastrointestinal symptoms, including constipation, in hemodialysis patients. Our study involved six patients over eight weeks and revealed no significant changes in constipation scores, remaining stable throughout the treatment.

Meanwhile, we noticed a significant reduction in serum phosphorus levels and a marked improvement in diarrhea scores. This suggests that while SFOH effectively managed phosphorus levels, it did not worsen constipation, which is a reassuring finding for patients concerned about gastrointestinal side effects.
7
Iron's minimal effect on constipation
We explored the effects of low-dose iron supplementation on gastrointestinal complaints, particularly constipation, in pregnant women. Conducting two randomized studies, we aimed to determine how different forms of iron—ferrous fumarate, ferrous bisglycinate, and ferrous sulphate—would affect the frequency of GI issues among healthy women throughout their pregnancy.

Through our investigations, we found that constipation was only significantly associated with higher doses of ferrous fumarate (80 mg/day). Interestingly, women taking lower doses of ferrous fumarate (20-60 mg/day) did not report more GI side effects, indicating that manageable doses of iron may be tolerated without significant worry about constipation.

Among the iron formulas tested, ferrous bisglycinate at 25 mg showed the best profile, resulting in fewer GI complaints overall compared to the others. In fact, it was linked to a lower incidence of black stools, which can often be associated with iron intake. Ultimately, we observed that while low-dose iron supplementation might incur some side effects, they are generally not severe enough to warrant a change in dosage or interruption of treatment.

References

  1. Milman NT, Bergholt T. Low-Dose Prophylactic Oral Iron Supplementation (Ferrous Fumarate, Ferrous Bisglycinate, and Ferrous Sulphate) in Pregnancy Is Not Associated With Clinically Significant Gastrointestinal Complaints: Results From Two Randomized Studies. J Pregnancy. 2024;2024:1716798. doi:10.1155/2024/1716798
  2. Banerjee A, Athalye S, Shingade P, Khargekar V, Mahajan N, et al. Efficacy of daily versus intermittent oral iron supplementation for prevention of anaemia among pregnant women: a systematic review and meta-analysis. EClinicalMedicine. 2024;74:102742. doi:10.1016/j.eclinm.2024.102742
  3. June D, Konstantin AT, Lumbanradja LA, Aryani A, Hengky A. Lactoferrin as treatment for iron-deficiency anemia in children: a systematic review. Turk J Pediatr. 2023;65:543. doi:10.24953/turkjped.2022.670
  4. Suzuki D, Ichie T, Hayashi H, Sugiura Y, Sugiyama T. Efficacy of sucroferric oxyhydroxide treatment in Japanese hemodialysis patients and its effect on gastrointestinal symptoms. Pharmazie. 2017;72:118. doi:10.1691/ph.2017.6848
  5. Abdel Moety GAF, Ali AM, Fouad R, Ramadan W, Belal DS, et al. Amino acid chelated iron versus an iron salt in the treatment of iron deficiency anemia with pregnancy: A randomized controlled study. Eur J Obstet Gynecol Reprod Biol. 2017;210:242. doi:10.1016/j.ejogrb.2017.01.003
  6. Pamuk GE, Uyanik MS, Top MS, Tapan U, Ak R, et al. Gastrointestinal symptoms are closely associated with depression in iron deficiency anemia: a comparative study. Ann Saudi Med. 2015;35:31. doi:10.5144/0256-4947.2015.31
  7. Smith GA, Fisher SA, Doree C, Di Angelantonio E, Roberts DJ. Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors. Cochrane Database Syst Rev. 2014;2014:CD009532. doi:10.1002/14651858.CD009532.pub2
  8. Pereira DI, Couto Irving SS, Lomer MC, Powell JJ. A rapid, simple questionnaire to assess gastrointestinal symptoms after oral ferrous sulphate supplementation. BMC Gastroenterol. 2014;14:103. doi:10.1186/1471-230X-14-103
  9. Bradley CS, Kennedy CM, Turcea AM, Rao SS, Nygaard IE. Constipation in pregnancy: prevalence, symptoms, and risk factors. Obstet Gynecol. 2007;110:1351.
  10. Singhal A, Morley R, Abbott R, Fairweather-Tait S, Stephenson T, et al. Clinical safety of iron-fortified formulas. Pediatrics. 2000;105:E38.
  11. Lloyd B, Halter RJ, Kuchan MJ, Baggs GE, Ryan AS, et al. Formula tolerance in postbreastfed and exclusively formula-fed infants. Pediatrics. 1999;103:E7.
  12. García-Milla P, Peñalver R, Nieto G. Formulation and Physical-Chemical Analysis of Functional Muffin Made with Inulin, Moringa, and Cacao Adapted for Elderly People with Parkinson's Disease. Antioxidants (Basel). 2024;13. doi:10.3390/antiox13060683
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