' 
SCIENTIFIC SCORE
Questionable
Based on 14 Researches
6.6
USERS' SCORE
Good
Based on 1 Review
8.6
Supplement Facts
Serving Size: 4 Capsules
Serving Per Container: 30
Amount Per Serving
%DV
Vitamin C (from culture of S. cerevisiae)
50 mg
56%
Vitamin D (as D3 from culture of S. cerevisiae)
40 mcg (1,600 IU)
200%
Vitamin K (from culture of S. cerevisiae)
120 mcg
100%
Calcium (naturally occurring from Algae)
1,100 mg
85%
Magnesium (from Algae and Dead Sea minerals)
357 mg
85%
Vitamin K (as K2 MK-7)
50 mcg
+
Strontium (naturally occurring from Algae)
3.8 mg
+
Boron (from Brown Rice Chelate)
3 mg
+
Silica (naturally occurring from Algae)
2.2 mg
+
Vanadium (naturally occurring from Algae)
25 mcg
+
Raw Probiotic & Enzyme BlendLipase, Protease, Aspergillopepsin, beta-Glucanase, Cellulase, Bromelain, Phytase, Lactase, Papain, Peptidase, Pectinase, Hemicellulase, Xylanase, [Lactobacillus bulgaricus, Lactobacillus plantarum] (500 Million CFU).
64 mg
+
Top Medical Research Studies
9
Vitamin D improves thyroid function
Effects of vitamin D supplementation on autoantibodies and thyroid function in patients with Hashimoto's thyroiditis: A systematic review and meta-analysis.
Directly assesses vitamin D's effects
We conducted a thorough exploration of how vitamin D supplementation can affect hypothyroidism, particularly in patients with Hashimoto's thyroiditis (HT). Our findings draw from a meta-analysis of twelve randomized controlled trials, involving a total of 862 participants. These studies compared the effects of vitamin D against placebo or no treatment, focusing on various thyroid function indicators and autoantibodies.
The results were promising. We found that vitamin D supplementation significantly reduced the levels of anti-thyroid antibodies, specifically thyroid peroxidase antibodies (TPO-Ab) and thyroglobulin antibodies (TG-Ab). Additionally, it appeared to enhance thyroid function by lowering thyroid-stimulating hormone (TSH) levels and increasing free triiodothyronine (FT3) and free thyroxine (FT4) levels.
Notably, we observed that active forms of vitamin D, like calcitriol, were more effective in reducing TPO-Ab compared to the more common D2 and D3 forms. We also noted that longer treatment durations, particularly those exceeding 12 weeks, led to greater improvements in thyroid hormone levels and antibody reductions.
Overall, our study suggests that vitamin D may play a beneficial role in managing Hashimoto’s thyroiditis, potentially helping to modulate immune responses and improve thyroid function.
The results were promising. We found that vitamin D supplementation significantly reduced the levels of anti-thyroid antibodies, specifically thyroid peroxidase antibodies (TPO-Ab) and thyroglobulin antibodies (TG-Ab). Additionally, it appeared to enhance thyroid function by lowering thyroid-stimulating hormone (TSH) levels and increasing free triiodothyronine (FT3) and free thyroxine (FT4) levels.
Notably, we observed that active forms of vitamin D, like calcitriol, were more effective in reducing TPO-Ab compared to the more common D2 and D3 forms. We also noted that longer treatment durations, particularly those exceeding 12 weeks, led to greater improvements in thyroid hormone levels and antibody reductions.
Overall, our study suggests that vitamin D may play a beneficial role in managing Hashimoto’s thyroiditis, potentially helping to modulate immune responses and improve thyroid function.
Read More
9
Vitamin D aids hypothyroid complications
Potential therapeutic impacts of vitamin D on hypothyroid-induced heart and kidney fibrosis and oxidative status in male rat.
Highly relevant to hypothyroid treatment
We investigated how vitamin D supplementation affects hypothyroidism, focusing on its impact on heart and kidney health. In our study, we used forty male Wistar rats, dividing them into four groups: control, hypothyroid, and hypothyroid treated with two doses of vitamin D. After six weeks, we examined various biochemical markers and evaluated fibrosis in the heart and kidneys.
Our findings revealed that hypothyroidism led to an increase in markers of kidney damage, like creatinine and urea, alongside elevated levels of oxidative stress markers in both heart and kidney tissues. Interestingly, we noticed that vitamin D treatment significantly reduced these harmful effects. The administration of vitamin D improved oxidative stress levels and decreased fibrosis in the heart and kidneys.
In conclusion, our study underlines the potential of vitamin D as a beneficial therapeutic option for alleviating some complications associated with hypothyroidism, particularly concerning tissue fibrosis and oxidative stress. This reinforces the idea that vitamin D could play a vital role in managing health issues related to thyroid hormone deficits.
Our findings revealed that hypothyroidism led to an increase in markers of kidney damage, like creatinine and urea, alongside elevated levels of oxidative stress markers in both heart and kidney tissues. Interestingly, we noticed that vitamin D treatment significantly reduced these harmful effects. The administration of vitamin D improved oxidative stress levels and decreased fibrosis in the heart and kidneys.
In conclusion, our study underlines the potential of vitamin D as a beneficial therapeutic option for alleviating some complications associated with hypothyroidism, particularly concerning tissue fibrosis and oxidative stress. This reinforces the idea that vitamin D could play a vital role in managing health issues related to thyroid hormone deficits.
Read More
8
Vitamin D's impact on hypothyroidism
Relationship between vitamin D and adolescents' hypothyroidism - a cross-sectional study.
Study shows correlation, not treatment
We aimed to understand how vitamin D, specifically measured as 25(OH)D, correlates with hypothyroidism in adolescents. Our study involved 180 participants from West Kazakhstan, and we carefully analyzed their blood samples for key indicators, including thyroid-stimulating hormone (TSH) and free thyroxine (T4).
The results were quite striking. We found that adolescents with low levels of vitamin D had significantly higher TSH levels and lower free T4 levels compared to those with normal vitamin D levels. Our data indicated that those who were vitamin D deficient were more likely to have both subclinical and clinical hypothyroidism.
Additionally, there was a noteworthy negative correlation between vitamin D levels and TSH, meaning as vitamin D decreased, TSH increased. Conversely, a positive correlation between vitamin D and free T4 suggested that higher vitamin D levels are associated with better thyroid function.
While this study shows a definite link between vitamin D deficiency and hypothyroidism in adolescents, it does not directly establish vitamin D treatment as a solution. The findings highlight the importance of maintaining adequate vitamin D levels for potential thyroid health, yet further research is needed to explore treatment effectiveness.
The results were quite striking. We found that adolescents with low levels of vitamin D had significantly higher TSH levels and lower free T4 levels compared to those with normal vitamin D levels. Our data indicated that those who were vitamin D deficient were more likely to have both subclinical and clinical hypothyroidism.
Additionally, there was a noteworthy negative correlation between vitamin D levels and TSH, meaning as vitamin D decreased, TSH increased. Conversely, a positive correlation between vitamin D and free T4 suggested that higher vitamin D levels are associated with better thyroid function.
While this study shows a definite link between vitamin D deficiency and hypothyroidism in adolescents, it does not directly establish vitamin D treatment as a solution. The findings highlight the importance of maintaining adequate vitamin D levels for potential thyroid health, yet further research is needed to explore treatment effectiveness.
Read More
Most Useful Reviews
9.5
Improved condition
The best 👍 My husband has hypothyroidism, and after starting this, his condition improved significantly. I will continue ordering it^^
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 14 Researches
6.6
- All Researches
9
Vitamin D aids hypothyroid complications
Potential therapeutic impacts of vitamin D on hypothyroid-induced heart and kidney fibrosis and oxidative status in male rat.
Highly relevant to hypothyroid treatment
We investigated how vitamin D supplementation affects hypothyroidism, focusing on its impact on heart and kidney health. In our study, we used forty male Wistar rats, dividing them into four groups: control, hypothyroid, and hypothyroid treated with two doses of vitamin D. After six weeks, we examined various biochemical markers and evaluated fibrosis in the heart and kidneys.
Our findings revealed that hypothyroidism led to an increase in markers of kidney damage, like creatinine and urea, alongside elevated levels of oxidative stress markers in both heart and kidney tissues. Interestingly, we noticed that vitamin D treatment significantly reduced these harmful effects. The administration of vitamin D improved oxidative stress levels and decreased fibrosis in the heart and kidneys.
In conclusion, our study underlines the potential of vitamin D as a beneficial therapeutic option for alleviating some complications associated with hypothyroidism, particularly concerning tissue fibrosis and oxidative stress. This reinforces the idea that vitamin D could play a vital role in managing health issues related to thyroid hormone deficits.
Our findings revealed that hypothyroidism led to an increase in markers of kidney damage, like creatinine and urea, alongside elevated levels of oxidative stress markers in both heart and kidney tissues. Interestingly, we noticed that vitamin D treatment significantly reduced these harmful effects. The administration of vitamin D improved oxidative stress levels and decreased fibrosis in the heart and kidneys.
In conclusion, our study underlines the potential of vitamin D as a beneficial therapeutic option for alleviating some complications associated with hypothyroidism, particularly concerning tissue fibrosis and oxidative stress. This reinforces the idea that vitamin D could play a vital role in managing health issues related to thyroid hormone deficits.
Read More
9
Vitamin D improves thyroid function
Effects of vitamin D supplementation on autoantibodies and thyroid function in patients with Hashimoto's thyroiditis: A systematic review and meta-analysis.
Directly assesses vitamin D's effects
We conducted a thorough exploration of how vitamin D supplementation can affect hypothyroidism, particularly in patients with Hashimoto's thyroiditis (HT). Our findings draw from a meta-analysis of twelve randomized controlled trials, involving a total of 862 participants. These studies compared the effects of vitamin D against placebo or no treatment, focusing on various thyroid function indicators and autoantibodies.
The results were promising. We found that vitamin D supplementation significantly reduced the levels of anti-thyroid antibodies, specifically thyroid peroxidase antibodies (TPO-Ab) and thyroglobulin antibodies (TG-Ab). Additionally, it appeared to enhance thyroid function by lowering thyroid-stimulating hormone (TSH) levels and increasing free triiodothyronine (FT3) and free thyroxine (FT4) levels.
Notably, we observed that active forms of vitamin D, like calcitriol, were more effective in reducing TPO-Ab compared to the more common D2 and D3 forms. We also noted that longer treatment durations, particularly those exceeding 12 weeks, led to greater improvements in thyroid hormone levels and antibody reductions.
Overall, our study suggests that vitamin D may play a beneficial role in managing Hashimoto’s thyroiditis, potentially helping to modulate immune responses and improve thyroid function.
The results were promising. We found that vitamin D supplementation significantly reduced the levels of anti-thyroid antibodies, specifically thyroid peroxidase antibodies (TPO-Ab) and thyroglobulin antibodies (TG-Ab). Additionally, it appeared to enhance thyroid function by lowering thyroid-stimulating hormone (TSH) levels and increasing free triiodothyronine (FT3) and free thyroxine (FT4) levels.
Notably, we observed that active forms of vitamin D, like calcitriol, were more effective in reducing TPO-Ab compared to the more common D2 and D3 forms. We also noted that longer treatment durations, particularly those exceeding 12 weeks, led to greater improvements in thyroid hormone levels and antibody reductions.
Overall, our study suggests that vitamin D may play a beneficial role in managing Hashimoto’s thyroiditis, potentially helping to modulate immune responses and improve thyroid function.
Read More
9
Vitamin D aids Hashimoto's outcomes
Therapeutic effect of vitamin D in Hashimoto's thyroiditis: a prospective, randomized and controlled clinical trial in China.
Study effectively explores supplementation impact
We aimed to investigate the effects of Vitamin D supplements on women recently diagnosed with Hashimoto's Thyroiditis (HT), a condition that can lead to hypothyroidism. This study was carefully structured as a randomized clinical trial that included a control group for comparison, allowing us to draw clearer conclusions about the effectiveness of Vitamin D.
Over six months, we observed that women receiving Vitamin D experienced significant health benefits. Specifically, those treated saw a notable decrease in Thyroid Peroxidase Antibody (TPOAb) levels, which is a marker of thyroid inflammation. Additionally, markers of thyroid function, such as Free Triiodothyronine (FT3) and Free Thyroxine (FT4), increased, while Thyroid-Stimulating Hormone (TSH) levels decreased. This combination of changes suggests that Vitamin D can help slow the progression of hypothyroidism and enhance thyroid function.
Overall, these findings indicate that Vitamin D supplementation can be a useful adjunct in managing Hashimoto's Thyroiditis, potentially leading to improved health outcomes for patients with this condition.
Over six months, we observed that women receiving Vitamin D experienced significant health benefits. Specifically, those treated saw a notable decrease in Thyroid Peroxidase Antibody (TPOAb) levels, which is a marker of thyroid inflammation. Additionally, markers of thyroid function, such as Free Triiodothyronine (FT3) and Free Thyroxine (FT4), increased, while Thyroid-Stimulating Hormone (TSH) levels decreased. This combination of changes suggests that Vitamin D can help slow the progression of hypothyroidism and enhance thyroid function.
Overall, these findings indicate that Vitamin D supplementation can be a useful adjunct in managing Hashimoto's Thyroiditis, potentially leading to improved health outcomes for patients with this condition.
Read More
9
Magnesium improves hypothyroid inflammation
Effect of magnesium sulfate and thyroxine on inflammatory markers in a rat model of hypothyroidism.
Combines treatments complicates results
We explored the interaction between magnesium sulfate and levothyroxine in managing inflammation related to hypothyroidism. In this study, we used 60 male rats, dividing them into six different groups. These included normals, those given magnesium, hypothyroid rats, and various combinations of treatments with levothyroxine and magnesium.
Our findings showed that hypothyroidism led to an increase in inflammatory markers such as C-reactive protein and interleukin-6, while decreasing vital thyroid hormones. When we treated hypothyroid rats with either levothyroxine or magnesium, these inflammatory markers significantly decreased.
Notably, the rats that received a combination of both treatments experienced the most significant reduction in inflammation. This suggests that chronic low-grade inflammation in hypothyroid conditions might elevate the risk of cardiovascular diseases. Overall, using magnesium and levothyroxine together seems to be more effective in reducing inflammation compared to either treatment alone.
Our findings showed that hypothyroidism led to an increase in inflammatory markers such as C-reactive protein and interleukin-6, while decreasing vital thyroid hormones. When we treated hypothyroid rats with either levothyroxine or magnesium, these inflammatory markers significantly decreased.
Notably, the rats that received a combination of both treatments experienced the most significant reduction in inflammation. This suggests that chronic low-grade inflammation in hypothyroid conditions might elevate the risk of cardiovascular diseases. Overall, using magnesium and levothyroxine together seems to be more effective in reducing inflammation compared to either treatment alone.
Read More
8
Vitamin D's impact on hypothyroidism
Relationship between vitamin D and adolescents' hypothyroidism - a cross-sectional study.
Study shows correlation, not treatment
We aimed to understand how vitamin D, specifically measured as 25(OH)D, correlates with hypothyroidism in adolescents. Our study involved 180 participants from West Kazakhstan, and we carefully analyzed their blood samples for key indicators, including thyroid-stimulating hormone (TSH) and free thyroxine (T4).
The results were quite striking. We found that adolescents with low levels of vitamin D had significantly higher TSH levels and lower free T4 levels compared to those with normal vitamin D levels. Our data indicated that those who were vitamin D deficient were more likely to have both subclinical and clinical hypothyroidism.
Additionally, there was a noteworthy negative correlation between vitamin D levels and TSH, meaning as vitamin D decreased, TSH increased. Conversely, a positive correlation between vitamin D and free T4 suggested that higher vitamin D levels are associated with better thyroid function.
While this study shows a definite link between vitamin D deficiency and hypothyroidism in adolescents, it does not directly establish vitamin D treatment as a solution. The findings highlight the importance of maintaining adequate vitamin D levels for potential thyroid health, yet further research is needed to explore treatment effectiveness.
The results were quite striking. We found that adolescents with low levels of vitamin D had significantly higher TSH levels and lower free T4 levels compared to those with normal vitamin D levels. Our data indicated that those who were vitamin D deficient were more likely to have both subclinical and clinical hypothyroidism.
Additionally, there was a noteworthy negative correlation between vitamin D levels and TSH, meaning as vitamin D decreased, TSH increased. Conversely, a positive correlation between vitamin D and free T4 suggested that higher vitamin D levels are associated with better thyroid function.
While this study shows a definite link between vitamin D deficiency and hypothyroidism in adolescents, it does not directly establish vitamin D treatment as a solution. The findings highlight the importance of maintaining adequate vitamin D levels for potential thyroid health, yet further research is needed to explore treatment effectiveness.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Improved condition
The best 👍 My husband has hypothyroidism, and after starting this, his condition improved significantly. I will continue ordering it^^
