We explored the connection between zinc deficiency and anemia through the case of an 18-year-old woman who faced a series of health issues, including urinary tract infections and insulin dysfunction. After a thorough assessment, she was diagnosed with zinc deficiency, shedding light on how this overlooked issue can impact overall health.
What stood out to us was the rapid recovery the patient experienced after beginning oral zinc supplementation. Zinc plays a critical role in numerous bodily functions, including immune support and protein regulation. By addressing her deficiency, we observed significant improvement in her symptoms, including anemia.
The patient’s diet contained high levels of substances that were inhibiting her zinc absorption, which likely contributed to her condition. This case emphasizes the importance of recognizing zinc deficiency as a potential underlying cause for unexplained health issues, particularly anemia. Prompt diagnosis and treatment can lead to a complete turnaround in the patient's health.
By sharing this experience, we hope to raise awareness among clinicians about the vital role of zinc in managing anemia and encourage timely interventions for patients showing diverse symptoms.
Read More
9
Zinc improves clozapine-related anemia
Successful Clozapine Treatment for Treatment-Resistant Schizophrenia With Zinc Deficiency Severe Anemia: A Case Report.
We observed an intriguing case involving a 51-year-old woman diagnosed with treatment-resistant schizophrenia (TRS) who developed severe anemia while undergoing clozapine therapy. This case highlights the complex relationship between clozapine, a potent antipsychotic, and zinc deficiency. Through identifying zinc deficiency as a possible contributing factor to the anemia, we explored how zinc supplementation could play a pivotal role in restoring hemoglobin levels.
Following zinc supplementation, we noted impressive improvements in her hemoglobin, allowing the patient to continue her clozapine at a therapeutic dosage. Remarkably, she has shown stability since, with no signs of recurrent anemia. While clozapine can lead to various complications, including anemia, this case suggests that addressing zinc levels may be critical for patients receiving this treatment.
However, we must acknowledge that the exact mechanism linking zinc deficiency and clozapine-related anemia remains unclear. Thus, further investigation is warranted to fully understand this relationship and the potential of zinc in managing anemia, particularly in patients on clozapine.
Read More
8
Zinc aids anemia reduction
Nutritional Management of Low Birth Weight and Preterm Infants in Low- and Low Middle-Income Countries.
We explored the impact of zinc treatment on anemia, particularly focusing on preterm and low birth weight infants in low- and middle-income countries. Previous evidence suggested a strong correlation between zinc supplementation and the reduction of anemia rates.
Our review revealed that adding zinc, along with other micronutrients, seems to show promising benefits. Specifically, it can help reduce levels of anemia in vulnerable populations, contributing to better health outcomes.
What's important to note is that benefits from zinc supplementation were often accompanied by other nutrients, making it challenging to isolate its specific effectiveness. Nevertheless, the consensus indicates that zinc, along with iron and vitamin A, plays a supportive role in promoting overall growth and reducing complications related to anemia.
Therefore, while we didn't claim that zinc alone is a catch-all solution, it does hold significant promise when combined with a broader nutritional strategy. This highlights the essential need for ongoing research into micronutrient supplementation in these high-risk groups.
Read More
Most Useful Reviews
9
Improved energy levels
1 people found this helpful
If you have anemia, this is for you! I have been using this product for many years. I take it during my period or when I feel fatigued, but I recommend that others who are anemic take the same brand of RAW iron and vitamin B12 daily. I have recommended it to several friends who are also anemic, and they all say it helps them feel better and get up in the morning. The quality is very good, but the price and frequent stock shortages are an issue.
Read More
7.5
Improved atopy symptoms
7 people found this helpful
It was good for a shortage of zinc. I started drinking this whilst breastfeeding due to symptoms of zinc deficiency. Before childbirth, I took a supplement for pregnant women which improved my anemia, and now I drink this to help my son with atopy. My condition improved comparatively, and my son's atopy noticeably improved as well. I believe only zinc wasn't the sole improvement but it certainly played a significant role alongside other supplements.
Read More
9
Raised iron levels
I take it for anaemia. It has significantly raised my iron and ferritin levels.
We observed an intriguing case involving a 51-year-old woman diagnosed with treatment-resistant schizophrenia (TRS) who developed severe anemia while undergoing clozapine therapy. This case highlights the complex relationship between clozapine, a potent antipsychotic, and zinc deficiency. Through identifying zinc deficiency as a possible contributing factor to the anemia, we explored how zinc supplementation could play a pivotal role in restoring hemoglobin levels.
Following zinc supplementation, we noted impressive improvements in her hemoglobin, allowing the patient to continue her clozapine at a therapeutic dosage. Remarkably, she has shown stability since, with no signs of recurrent anemia. While clozapine can lead to various complications, including anemia, this case suggests that addressing zinc levels may be critical for patients receiving this treatment.
However, we must acknowledge that the exact mechanism linking zinc deficiency and clozapine-related anemia remains unclear. Thus, further investigation is warranted to fully understand this relationship and the potential of zinc in managing anemia, particularly in patients on clozapine.
Read More
9
Zinc deficiency linked to anemia
Zinc Deficiency Presenting With Diverse Symptoms in a Young Patient: A Case Report.
We explored the connection between zinc deficiency and anemia through the case of an 18-year-old woman who faced a series of health issues, including urinary tract infections and insulin dysfunction. After a thorough assessment, she was diagnosed with zinc deficiency, shedding light on how this overlooked issue can impact overall health.
What stood out to us was the rapid recovery the patient experienced after beginning oral zinc supplementation. Zinc plays a critical role in numerous bodily functions, including immune support and protein regulation. By addressing her deficiency, we observed significant improvement in her symptoms, including anemia.
The patient’s diet contained high levels of substances that were inhibiting her zinc absorption, which likely contributed to her condition. This case emphasizes the importance of recognizing zinc deficiency as a potential underlying cause for unexplained health issues, particularly anemia. Prompt diagnosis and treatment can lead to a complete turnaround in the patient's health.
By sharing this experience, we hope to raise awareness among clinicians about the vital role of zinc in managing anemia and encourage timely interventions for patients showing diverse symptoms.
Read More
8
Zinc improves anaemia outcomes
Predictors of Anaemia Among Young Children Receiving Daily Micronutrient Powders (MNPs) for 24 Weeks in Bangladesh: A Secondary Analysis of the Zinc in Powders Trial.
We set out to explore how zinc, through micronutrient powders (MNPs), influences anaemia in young children, particularly in Bangladesh, where high rates of anaemia persist. In a well-structured trial, we observed children aged 9-11 months receiving daily doses of MNPs for 24 weeks. Initially, a staggering 54.1% of these children had anaemia, characterized by low hemoglobin levels.
At the end of the study, anaemia prevalence decreased to 32.6%, indicating some positive effects of the MNPs, which included zinc as one of their components. However, while we found various factors associated with anaemia—like underweight status and frequent illness—it's crucial to note that we could not isolate the specific impact of zinc on anaemia from other nutritional interventions included in the powders.
Overall, we acknowledged that while MNPs contribute to addressing anaemia, they should be part of a broader strategy that encompasses other factors impacting health and nutrition. This comprehensive approach ensures effective prevention and control of anaemia in vulnerable populations.
Read More
8
Zinc aids anemia reduction
Nutritional Management of Low Birth Weight and Preterm Infants in Low- and Low Middle-Income Countries.
We explored the impact of zinc treatment on anemia, particularly focusing on preterm and low birth weight infants in low- and middle-income countries. Previous evidence suggested a strong correlation between zinc supplementation and the reduction of anemia rates.
Our review revealed that adding zinc, along with other micronutrients, seems to show promising benefits. Specifically, it can help reduce levels of anemia in vulnerable populations, contributing to better health outcomes.
What's important to note is that benefits from zinc supplementation were often accompanied by other nutrients, making it challenging to isolate its specific effectiveness. Nevertheless, the consensus indicates that zinc, along with iron and vitamin A, plays a supportive role in promoting overall growth and reducing complications related to anemia.
Therefore, while we didn't claim that zinc alone is a catch-all solution, it does hold significant promise when combined with a broader nutritional strategy. This highlights the essential need for ongoing research into micronutrient supplementation in these high-risk groups.
Read More
4
Zinc's uncertain effect on anemia
Effect of Micronutrients on HIV-Related Clinical Outcomes Among Adults Living With HIV on Antiretroviral Therapy: Systematic Review and Meta-analysis.
We examined how zinc supplementation affects anemia in people living with HIV who are on antiretroviral therapy. This review included various studies that looked at the relationship between zinc intake and anemia outcomes.
Overall, the findings suggest that zinc supplementation had little to no significant effect on hemoglobin levels, which is one of the key indicators of anemia. Although the study indicated some uncertainty regarding its impact, we found that as serum zinc levels increased by 10 µg/dL, the expected increase in CD4 lymphocyte count slightly decreased.
This means that while zinc may play a role in immune health, its direct effect on alleviating anemia in this population is not clearly defined. It’s important to note that the evidence surrounding zinc and its impact on hemoglobin concentration remains inconclusive, and further research is needed to clarify its role.
If you have anemia, this is for you! I have been using this product for many years. I take it during my period or when I feel fatigued, but I recommend that others who are anemic take the same brand of RAW iron and vitamin B12 daily. I have recommended it to several friends who are also anemic, and they all say it helps them feel better and get up in the morning. The quality is very good, but the price and frequent stock shortages are an issue.
Read More
7.5
Improved atopy symptoms
7 people found this helpful
It was good for a shortage of zinc. I started drinking this whilst breastfeeding due to symptoms of zinc deficiency. Before childbirth, I took a supplement for pregnant women which improved my anemia, and now I drink this to help my son with atopy. My condition improved comparatively, and my son's atopy noticeably improved as well. I believe only zinc wasn't the sole improvement but it certainly played a significant role alongside other supplements.
Read More
9
Raised iron levels
I take it for anaemia. It has significantly raised my iron and ferritin levels.
Read More
7.5
Supports hair and nails
3 people found this helpful
Zinc in an excellent dose of 30mg. More than 50 mg per day is not recommended. It helps significantly with hair, skin, nails, and as part of complex therapy for anaemia. Can also be beneficial for men's health. Thank you, iHerb! I’m very happy with the purchase.
Read More
7.5
Improved nail health
I order regularly; after taking this, the white stripes on my nails disappeared and both the colour and structure of my nails improved. It is included in my therapy for anaemia. The product is gentle on my stomach and not irritating.
Anemia is a medical condition characterized by a deficiency of red blood cells or hemoglobin in the blood, which can result in reduced oxygen flow to the body's organs. The most common type of anemia is iron-deficiency anemia, which occurs when the body does not have enough iron to produce adequate hemoglobin. Other types can arise from chronic diseases, genetic conditions, or a lack of certain vitamins such as B12 or folate. Symptoms often include fatigue, weakness, pale skin, and shortness of breath, particularly during physical activity.
Diagnosing anemia typically involves blood tests to measure levels of red blood cells, hemoglobin concentration, and other related factors. Treatment varies depending on the underlying cause but may include dietary changes, supplements, or medications. In some cases, more serious interventions may be necessary, such as blood transfusions or treatments for associated conditions. If you suspect you have anemia, it's essential to consult a healthcare professional for appropriate evaluation and management.
Zinc is a versatile metal known for its various applications in industry and health. It is a bluish-white metallic element represented by the symbol Zn and atomic number 30 on the periodic table. Zinc is primarily used for galvanizing steel to prevent rusting, in the manufacturing of alloys, and as a component in batteries. Additionally, zinc plays a crucial role in biological processes, making it an essential trace element in the human diet. It is involved in immune function, protein synthesis, wound healing, and DNA synthesis, highlighting its importance in maintaining overall health and well-being.
Zinc plays a crucial role in multiple bodily functions, including immune response and cell division, but its direct impact on anemia is more complex. While zinc deficiency can lead to various health issues, including some forms of anemia, it is not a primary treatment for anemia itself. The most common type of anemia, iron-deficiency anemia, requires an increased intake of iron along with other supportive vitamins such as vitamin B12 and folic acid. Zinc does contribute to overall nutritional balance and can support hematopoiesis (the production of blood cells), but increasing zinc intake alone is not a solution for those suffering from anemia.
If you suspect or have been diagnosed with anemia, it's essential to consult with a healthcare professional to determine the most appropriate treatment plan tailored specifically to your needs. They may recommend dietary changes, supplements, or other interventions based on the type and underlying causes of anemia. In summary, while zinc can play a supportive role in maintaining overall health and could potentially impact certain types of anemia derived from deficiencies, it should not be seen as a standalone solution for managing this condition.
Based on user reviews, the time it typically takes to see results from taking this supplement for anemia varies, but many users report noticeable improvements in their iron levels and overall well-being within a relatively short period. For instance, one user mentioned that the product has significantly raised their iron and ferritin levels, suggesting effectiveness in improving anemia symptoms Read Review. Another reviewer highlighted using the supplement during specific times, which helped them feel better and more energized Read Review.
While individual experiences may differ, it appears that consistent daily use of the supplement can lead to positive outcomes. Users often combine it with other nutrients such as vitamin B12 for compounded benefits, indicating that overall dietary habits may also influence the speed and extent of improvements Read Review. Therefore, it is advisable to monitor your progress after a few weeks of consistent intake to better gauge its effectiveness on your anemia.
The scientific research surrounding zinc supplementation for anemia presents a mixed picture. A study focusing on young Bangladeshi children demonstrated that micronutrient powders containing zinc led to a notable decrease in anemia prevalence, from 54.1% to 32.6% over 24 weeks. However, it was difficult to pinpoint zinc’s specific contribution since the intervention also included other crucial nutrients [1]. Similarly, a case study involving a patient on clozapine therapy who developed severe anemia highlighted zinc's potential benefits; her hemoglobin levels improved after zinc supplementation, suggesting a positive impact on her condition [2].
On the other hand, research examining the effect of zinc in adults with HIV on antiretroviral therapy revealed that zinc supplementation had little to no significant effect on hemoglobin levels [4]. Another review suggested that zinc alone may not be the sole solution for reducing anemia, although it plays a role alongside other critical nutrients [3]. Therefore, while zinc shows promise in certain settings, its isolated effectiveness in anemia management is inconclusive, indicating a need for further research to clarify its role within broader nutritional strategies.
Users have reported a variety of improvements in their symptoms after using the supplement for anemia. Many have emphasized how their iron levels have significantly increased, with one user specifically noting that their iron and ferritin levels rose considerably, marking a clear benefit in managing anemia symptoms Read Review. Additional feedback highlights that users feel more energized and capable of facing daily activities, especially during times of fatigue, such as menstrual cycles, suggesting enhanced vitality overall Read Review.
Moreover, some users have noted ancillary benefits such as improvements in hair, skin, and nail health, with one individual mentioning the disappearance of white stripes on their nails Read Review. Others connected the supplement's efficacy not just to the iron content but also to a synergistic effect with additional nutrients like zinc, indicating that a holistic approach to supplementation could yield even better results Read Review. While these anecdotal accounts provide a promising outlook, it's essential to keep in mind that individual results may vary based on personal health conditions, dietary habits, and adherence to recommended dosages.
Users have shared insights about the benefits of combining this supplement with other products to manage anemia more effectively. Specifically, one user highlighted the importance of taking RAW iron and vitamin B12 daily as a complementary strategy for those dealing with anemia, noting that this combination helps them feel more energized, particularly during periods of fatigue Read Review. This sentiment is echoed by another reviewer who discussed the coexistence of zinc supplementation alongside their existing regimen, suggesting that the addition of zinc improved their overall condition and played a significant role in alleviating symptoms Read Review.
Moreover, several reviews pointed to the broader benefits of zinc as part of complex therapy aimed at tackling anemia. Users have reported that zinc, when taken at appropriate doses, not only supports anemia management but also positively influences hair, skin, and nail health Read Review. This integrative approach appears to enhance the supplement's effectiveness, leading to comprehensive improvements in overall well-being for individuals facing iron deficiency Read Review.
Users report a positive experience when incorporating Zinc into their regimen for treating anemia, with many experiencing notable improvements in their health. One user highlighted that a dosage of 30mg of Zinc was effective, emphasizing that doses higher than 50mg may not be advisable (Read Review). Another user mentioned that Zinc, when combined with other supplements, played a significant role in improving their anemia symptoms (Read Review).
Several reviewers indicated that the Zinc supplements not only helped with anemia but also contributed to general health improvements, impacting areas like hair, skin, and nails. One user specifically noted a significant increase in their iron and ferritin levels after taking the supplement (Read Review). Overall, while users found Zinc beneficial, the consensus seems to be that it's often most effective when part of a multi-supplement approach tailored to individual needs.
9
Raised iron levels
I take it for anaemia. It has significantly raised my iron and ferritin levels.
9
Improved energy levels
1 people found this helpful
If you have anemia, this is for you! I have been using this product for many years. I take it during my period or when I feel fatigued, but I recommend that others who are anemic take the same brand of RAW iron and vitamin B12 daily. I have recommended it to several friends who are also anemic, and they all say it helps them feel better and get up in the morning. The quality is very good, but the price and frequent stock shortages are an issue.
7.5
Improved nail health
I order regularly; after taking this, the white stripes on my nails disappeared and both the colour and structure of my nails improved. It is included in my therapy for anaemia. The product is gentle on my stomach and not irritating.
7.5
Improved atopy symptoms
7 people found this helpful
It was good for a shortage of zinc. I started drinking this whilst breastfeeding due to symptoms of zinc deficiency. Before childbirth, I took a supplement for pregnant women which improved my anemia, and now I drink this to help my son with atopy. My condition improved comparatively, and my son's atopy noticeably improved as well. I believe only zinc wasn't the sole improvement but it certainly played a significant role alongside other supplements.
7.5
Supports hair and nails
3 people found this helpful
Zinc in an excellent dose of 30mg. More than 50 mg per day is not recommended. It helps significantly with hair, skin, nails, and as part of complex therapy for anaemia. Can also be beneficial for men's health. Thank you, iHerb! I’m very happy with the purchase.
8
Zinc improves anaemia outcomes
Predictors of Anaemia Among Young Children Receiving Daily Micronutrient Powders (MNPs) for 24 Weeks in Bangladesh: A Secondary Analysis of the Zinc in Powders Trial.
We set out to explore how zinc, through micronutrient powders (MNPs), influences anaemia in young children, particularly in Bangladesh, where high rates of anaemia persist. In a well-structured trial, we observed children aged 9-11 months receiving daily doses of MNPs for 24 weeks. Initially, a staggering 54.1% of these children had anaemia, characterized by low hemoglobin levels.
At the end of the study, anaemia prevalence decreased to 32.6%, indicating some positive effects of the MNPs, which included zinc as one of their components. However, while we found various factors associated with anaemia—like underweight status and frequent illness—it's crucial to note that we could not isolate the specific impact of zinc on anaemia from other nutritional interventions included in the powders.
Overall, we acknowledged that while MNPs contribute to addressing anaemia, they should be part of a broader strategy that encompasses other factors impacting health and nutrition. This comprehensive approach ensures effective prevention and control of anaemia in vulnerable populations.
9
Zinc improves clozapine-related anemia
Successful Clozapine Treatment for Treatment-Resistant Schizophrenia With Zinc Deficiency Severe Anemia: A Case Report.
We observed an intriguing case involving a 51-year-old woman diagnosed with treatment-resistant schizophrenia (TRS) who developed severe anemia while undergoing clozapine therapy. This case highlights the complex relationship between clozapine, a potent antipsychotic, and zinc deficiency. Through identifying zinc deficiency as a possible contributing factor to the anemia, we explored how zinc supplementation could play a pivotal role in restoring hemoglobin levels.
Following zinc supplementation, we noted impressive improvements in her hemoglobin, allowing the patient to continue her clozapine at a therapeutic dosage. Remarkably, she has shown stability since, with no signs of recurrent anemia. While clozapine can lead to various complications, including anemia, this case suggests that addressing zinc levels may be critical for patients receiving this treatment.
However, we must acknowledge that the exact mechanism linking zinc deficiency and clozapine-related anemia remains unclear. Thus, further investigation is warranted to fully understand this relationship and the potential of zinc in managing anemia, particularly in patients on clozapine.
4
Zinc's uncertain effect on anemia
Effect of Micronutrients on HIV-Related Clinical Outcomes Among Adults Living With HIV on Antiretroviral Therapy: Systematic Review and Meta-analysis.
We examined how zinc supplementation affects anemia in people living with HIV who are on antiretroviral therapy. This review included various studies that looked at the relationship between zinc intake and anemia outcomes.
Overall, the findings suggest that zinc supplementation had little to no significant effect on hemoglobin levels, which is one of the key indicators of anemia. Although the study indicated some uncertainty regarding its impact, we found that as serum zinc levels increased by 10 µg/dL, the expected increase in CD4 lymphocyte count slightly decreased.
This means that while zinc may play a role in immune health, its direct effect on alleviating anemia in this population is not clearly defined. It’s important to note that the evidence surrounding zinc and its impact on hemoglobin concentration remains inconclusive, and further research is needed to clarify its role.
8
Zinc aids anemia reduction
Nutritional Management of Low Birth Weight and Preterm Infants in Low- and Low Middle-Income Countries.
We explored the impact of zinc treatment on anemia, particularly focusing on preterm and low birth weight infants in low- and middle-income countries. Previous evidence suggested a strong correlation between zinc supplementation and the reduction of anemia rates.
Our review revealed that adding zinc, along with other micronutrients, seems to show promising benefits. Specifically, it can help reduce levels of anemia in vulnerable populations, contributing to better health outcomes.
What's important to note is that benefits from zinc supplementation were often accompanied by other nutrients, making it challenging to isolate its specific effectiveness. Nevertheless, the consensus indicates that zinc, along with iron and vitamin A, plays a supportive role in promoting overall growth and reducing complications related to anemia.
Therefore, while we didn't claim that zinc alone is a catch-all solution, it does hold significant promise when combined with a broader nutritional strategy. This highlights the essential need for ongoing research into micronutrient supplementation in these high-risk groups.
References
Thompson L, Arnold C, Peerson J, Long JM, Westcott JLE, et al. Predictors of Anaemia Among Young Children Receiving Daily Micronutrient Powders (MNPs) for 24 Weeks in Bangladesh: A Secondary Analysis of the Zinc in Powders Trial. Matern Child Nutr. 2025. doi:10.1111/mcn.13806
Matsuo-Yamamoto K, Uenishi S, Ishiyama Y, Yamada S, Kitabata Y, et al. Successful Clozapine Treatment for Treatment-Resistant Schizophrenia With Zinc Deficiency Severe Anemia: A Case Report. Neuropsychopharmacol Rep. 2025;45:e12526. doi:10.1002/npr2.12526
Azhar M, Yasin R, Hanif S, Bughio SA, Das JK, et al. Nutritional Management of Low Birth Weight and Preterm Infants in Low- and Low Middle-Income Countries. Neonatology. 2025;122:209. doi:10.1159/000542154
Okoka EM, Kuyebi MA, Oyadiran OT, Okusanya TR, Onaku E, et al. Effect of Micronutrients on HIV-Related Clinical Outcomes Among Adults Living With HIV on Antiretroviral Therapy: Systematic Review and Meta-analysis. Nutr Rev. 2024. doi:10.1093/nutrit/nuae171
Vicente IST, Fleuri LF, Xavier WDS, Guimarães MG, de Carvalho PLPF, et al. The Effects of Dietary Orange Peel Fragments Enriched with Zinc and Vitamins C and E on the Antioxidant and Immune Responses of Nile Tilapia under Stress Conditions. Animals (Basel). 2024;14. doi:10.3390/ani14202962
Inoue M. Zinc Deficiency Presenting With Diverse Symptoms in a Young Patient: A Case Report. Cureus. 2024;16:e66034. doi:10.7759/cureus.66034
Mohammad Shafiee S, Amiri F, Yousefi F, Akbari Nasab N. Pro-Oxidant/ Antioxidant Balance Correlates with Red Blood Cell Indices and Anemia Severity in the Anemic Patients. Rep Biochem Mol Biol. 2024;12:609. doi:10.61186/rbmb.12.4.609