Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.9
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.8
Supplement Facts
Serving Size: 2 Softgels
Serving Per Container: 60
Amount Per Serving
%DV
Calories
20
Total Fat
2 g
3%‡
Cholesterol
11 mg
4%‡
Protein
<1 g
Fish Oil Concentrate^
2,000 mg
†
Omega-3 Fatty Acids^
1,200 mg
†
EPA (Eicosapentaenoic acid)^
800 mg
†
DHA (Docosahexaenoic acid)^
400 mg
†
Top Medical Research Studies
9
We investigated the impact of diabetes on the levels of docosahexaenoic acid (DHA), an essential omega 3 fatty acid, in the retina of humans and mice. Our findings revealed that diabetic individuals had significantly lower DHA levels—40% less in peripheral regions and 25% less in the macula—compared to those without diabetes.
Additionally, we observed a reduction of retinal thickness and function in diabetic mice. Although there’s potential for dietary DHA to help with diabetic retinopathy, the current study suggests that diabetes is linked to reduced DHA and related retinal defects.
Additionally, we observed a reduction of retinal thickness and function in diabetic mice. Although there’s potential for dietary DHA to help with diabetic retinopathy, the current study suggests that diabetes is linked to reduced DHA and related retinal defects.
Read More
9
We examined the impact of omega-3 fatty acids from fish oil on diabetes in nonobese Goto-Kakizaki rats. Over eight weeks, these rats received fish oil supplements, while control groups were given plain water.
Our findings revealed that fish oil significantly enhanced glucose tolerance and insulin sensitivity in the diabetic rats. Additionally, it shifted T lymphocyte activity towards more immune-regulating patterns, reducing inflammation and promoting better overall metabolic health.
However, the study primarily involved animal models, so further research is needed to confirm these results in humans.
Our findings revealed that fish oil significantly enhanced glucose tolerance and insulin sensitivity in the diabetic rats. Additionally, it shifted T lymphocyte activity towards more immune-regulating patterns, reducing inflammation and promoting better overall metabolic health.
However, the study primarily involved animal models, so further research is needed to confirm these results in humans.
Read More
9
Omega-3 lowers type 2 diabetes odds
We conducted a study analyzing dietary omega-3 and omega-6 fatty acids and their connection to type 2 diabetes (T2DM) risk. Using data from 8,744 participants, we found that higher omega-3 intake was linked to a 58% lower chance of developing T2DM.
In contrast, a high omega-6 to omega-3 ratio appeared to increase the likelihood of T2DM. However, dietary omega-6 on its own didn’t show a significant effect in relation to diabetes risk. These findings suggest that enhancing omega-3 intake might be beneficial in managing T2DM risk.
In contrast, a high omega-6 to omega-3 ratio appeared to increase the likelihood of T2DM. However, dietary omega-6 on its own didn’t show a significant effect in relation to diabetes risk. These findings suggest that enhancing omega-3 intake might be beneficial in managing T2DM risk.
Read More
Most Useful Reviews
7.5
Reduces systemic inflammation
A good, high-quality omega that lowers cholesterol, alleviates systemic inflammation, and reduces triglycerides in the blood, particularly beneficial for type 2 diabetes.
Read More
7.5
Balances omega ratios
This product is excellent. It perfectly balances the proportions of omega-6 to omega-3, making it ideal for individuals with diabetes and for reducing inflammation in the body.
Read More
6
Great value omega
Excellent! This is not the first time I have ordered this omega. It offers great value for money! The combined intake of EPA-DHA acids reduces the risk of type 2 diabetes, heart disease, and malignancies. These acids also significantly improve learning and memory.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.9
- All Researches
9
We investigated the impact of diabetes on the levels of docosahexaenoic acid (DHA), an essential omega 3 fatty acid, in the retina of humans and mice. Our findings revealed that diabetic individuals had significantly lower DHA levels—40% less in peripheral regions and 25% less in the macula—compared to those without diabetes.
Additionally, we observed a reduction of retinal thickness and function in diabetic mice. Although there’s potential for dietary DHA to help with diabetic retinopathy, the current study suggests that diabetes is linked to reduced DHA and related retinal defects.
Additionally, we observed a reduction of retinal thickness and function in diabetic mice. Although there’s potential for dietary DHA to help with diabetic retinopathy, the current study suggests that diabetes is linked to reduced DHA and related retinal defects.
Read More
9
We examined the impact of omega-3 fatty acids from fish oil on diabetes in nonobese Goto-Kakizaki rats. Over eight weeks, these rats received fish oil supplements, while control groups were given plain water.
Our findings revealed that fish oil significantly enhanced glucose tolerance and insulin sensitivity in the diabetic rats. Additionally, it shifted T lymphocyte activity towards more immune-regulating patterns, reducing inflammation and promoting better overall metabolic health.
However, the study primarily involved animal models, so further research is needed to confirm these results in humans.
Our findings revealed that fish oil significantly enhanced glucose tolerance and insulin sensitivity in the diabetic rats. Additionally, it shifted T lymphocyte activity towards more immune-regulating patterns, reducing inflammation and promoting better overall metabolic health.
However, the study primarily involved animal models, so further research is needed to confirm these results in humans.
Read More
9
Omega-3 lowers type 2 diabetes odds
We conducted a study analyzing dietary omega-3 and omega-6 fatty acids and their connection to type 2 diabetes (T2DM) risk. Using data from 8,744 participants, we found that higher omega-3 intake was linked to a 58% lower chance of developing T2DM.
In contrast, a high omega-6 to omega-3 ratio appeared to increase the likelihood of T2DM. However, dietary omega-6 on its own didn’t show a significant effect in relation to diabetes risk. These findings suggest that enhancing omega-3 intake might be beneficial in managing T2DM risk.
In contrast, a high omega-6 to omega-3 ratio appeared to increase the likelihood of T2DM. However, dietary omega-6 on its own didn’t show a significant effect in relation to diabetes risk. These findings suggest that enhancing omega-3 intake might be beneficial in managing T2DM risk.
Read More
9
We aimed to understand if docosahexaenoic acid (DHA) could protect diabetic mice from ischemic stroke. After administering DHA, we observed a significant reduction in brain injury and improved neurological function in these mice after stroke.
The treatment appeared to lower inflammation and cell death, as indicated by less neutrophils in the brain and changes in important proteins. Overall, DHA showed promise in managing stroke's damaging effects in diabetic models, suggesting potential benefits for clinical practice in diabetes care.
The treatment appeared to lower inflammation and cell death, as indicated by less neutrophils in the brain and changes in important proteins. Overall, DHA showed promise in managing stroke's damaging effects in diabetic models, suggesting potential benefits for clinical practice in diabetes care.
Read More
9
Omega-3 reduces inflammation, diabetes risk
We tested the effects of omega-3 fatty acids, specifically EPA and DHA, on diabetes risk factors linked to high levels of "bad" cholesterol. Over a 12-week period, individuals with elevated lipoprotein levels received daily omega-3 supplements.
We found that this intervention significantly reduced inflammation in fat tissue, improving factors like insulin function and fat metabolism. Overall, omega-3 supplementation showed promising results in lowering diabetes risk through its positive effects on inflammatory pathways.
However, while benefits were observed, the results indicated the need for further studies to fully understand the long-term impacts.
We found that this intervention significantly reduced inflammation in fat tissue, improving factors like insulin function and fat metabolism. Overall, omega-3 supplementation showed promising results in lowering diabetes risk through its positive effects on inflammatory pathways.
However, while benefits were observed, the results indicated the need for further studies to fully understand the long-term impacts.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Reduces systemic inflammation
A good, high-quality omega that lowers cholesterol, alleviates systemic inflammation, and reduces triglycerides in the blood, particularly beneficial for type 2 diabetes.
Read More
7.5
Balances omega ratios
This product is excellent. It perfectly balances the proportions of omega-6 to omega-3, making it ideal for individuals with diabetes and for reducing inflammation in the body.
Read More
6
Great value omega
Excellent! This is not the first time I have ordered this omega. It offers great value for money! The combined intake of EPA-DHA acids reduces the risk of type 2 diabetes, heart disease, and malignancies. These acids also significantly improve learning and memory.
Read More
5
Prevention of diabetes
Omega-3 fatty acids diminish the risk of heart and vascular diseases, enhance blood circulation, and improve cognitive functions such as memory and concentration. They also lower blood pressure and are beneficial for the prevention of diabetes mellitus.
Read More
6
Supports diabetes management
Good pure omega that helps with atherosclerosis and diabetes. It normalises cholesterol and contributes to alleviating joint problems.
Read More
Frequently Asked Questions
7.5
Reduces systemic inflammation
A good, high-quality omega that lowers cholesterol, alleviates systemic inflammation, and reduces triglycerides in the blood, particularly beneficial for type 2 diabetes.
7.5
Balances omega ratios
This product is excellent. It perfectly balances the proportions of omega-6 to omega-3, making it ideal for individuals with diabetes and for reducing inflammation in the body.
6
Great value omega
Excellent! This is not the first time I have ordered this omega. It offers great value for money! The combined intake of EPA-DHA acids reduces the risk of type 2 diabetes, heart disease, and malignancies. These acids also significantly improve learning and memory.
5
Prevention of diabetes
Omega-3 fatty acids diminish the risk of heart and vascular diseases, enhance blood circulation, and improve cognitive functions such as memory and concentration. They also lower blood pressure and are beneficial for the prevention of diabetes mellitus.
6
Supports diabetes management
Good pure omega that helps with atherosclerosis and diabetes. It normalises cholesterol and contributes to alleviating joint problems.
9
We examined the impact of omega-3 fatty acids from fish oil on diabetes in nonobese Goto-Kakizaki rats. Over eight weeks, these rats received fish oil supplements, while control groups were given plain water.
Our findings revealed that fish oil significantly enhanced glucose tolerance and insulin sensitivity in the diabetic rats. Additionally, it shifted T lymphocyte activity towards more immune-regulating patterns, reducing inflammation and promoting better overall metabolic health.
However, the study primarily involved animal models, so further research is needed to confirm these results in humans.
Our findings revealed that fish oil significantly enhanced glucose tolerance and insulin sensitivity in the diabetic rats. Additionally, it shifted T lymphocyte activity towards more immune-regulating patterns, reducing inflammation and promoting better overall metabolic health.
However, the study primarily involved animal models, so further research is needed to confirm these results in humans.
7
We examined the connection between polyunsaturated fatty acids (PUFAs) and diabetes risk among older Italians in a cross-sectional study. By analyzing data from over 4,400 participants aged 65 and up, we found that higher consumption of omega-3s—especially EPA and DHA—was linked to lower blood glucose levels and decreased diabetes prevalence. Interestingly, while these fats showed beneficial effects, higher body mass index (BMI) values were associated with some omega-6 fats. Overall, our findings suggest dietary PUFAs may play a role in managing diabetes in older adults.
7
We investigated whether a supplement rich in docosahexaenoic acid (DHA) could help reduce harmful lipids in individuals with type 2 diabetes and painful neuropathy. Our study involved 40 participants who took DHA and eicosapentaenoic acid (EPA) daily while attending educational sessions. After three months, we found significant reductions in neurotoxic lipids and an improvement in pain symptoms. This suggests that omega-3 fatty acids may be beneficial in managing diabetic neuropathy, contributing to better overall health.
7
We conducted a study to see how different fish oils impact cholesterol levels in diabetic rats. We fed male Zucker Diabetic Sprague Dawley rats herring oil, anchovy oil, or a control diet over five weeks.
The results showed that those consuming herring oil had a 14% lower total cholesterol concentration compared to the other groups. The herring oil also increased bile acid excretion, indicating some effects on cholesterol metabolism.
However, anchovy oil did not have any significant benefits on cholesterol levels. Overall, herring oil showed promise for lowering cholesterol in this diabetic model.
The results showed that those consuming herring oil had a 14% lower total cholesterol concentration compared to the other groups. The herring oil also increased bile acid excretion, indicating some effects on cholesterol metabolism.
However, anchovy oil did not have any significant benefits on cholesterol levels. Overall, herring oil showed promise for lowering cholesterol in this diabetic model.
References
- Sugasini D, Yalagala PCR, Park JC, Ma G, Farooq Z, et al. Retinal Docosahexaenoic Acid Is Significantly Reduced in Diabetic Humans and Mice: Possible Relationship to Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2024;65:39. doi:10.1167/iovs.65.14.39
- Lobato TB, Santos ESS, Iser-Bem PN, Falcão HS, Gimenes GM, et al. Omega-3 Fatty Acids Weaken Lymphocyte Inflammatory Features and Improve Glycemic Control in Nonobese Diabetic Goto-Kakizaki Rats. Nutrients. 2024;16. doi:10.3390/nu16234106
- Coelho-Júnior HJ, Álvarez-Bustos A, Picca A, Calvani R, Rodriguez-Mañas L, et al. Dietary Intake of Polyunsaturated Fatty Acids Is Associated with Blood Glucose and Diabetes in Community-Dwelling Older Adults. Nutrients. 2024;16. doi:10.3390/nu16234087
- Durán AM, Zamora F, De León M. Dietary Docosahexaenoic Acid-Rich Supplementation Decreases Neurotoxic Lipid Mediators in Participants with Type 2 Diabetes and Neuropathic Pain. Nutrients. 2024;16. doi:10.3390/nu16234025
- Soria-Utrilla V, Sasso CV, Romero-Zerbo SY, Adarve-Castro A, López-Urdiales R, et al. Biomarkers of oxidation, inflammation and intestinal permeability in persons with diabetes mellitus with parenteral nutrition: A multicenter randomized trial. Clin Nutr. 2025;44:155. doi:10.1016/j.clnu.2024.11.044
- You Y, Sarkar S, Deiter C, Elliott EC, Nicora CD, et al. Reduction of Chemokine CXCL9 Expression by Omega-3 Fatty Acids via ADP-Ribosylhydrolase ARH3 in MIN6 Insulin-Producing Cells. Proteomics. 2025;25:e202400053. doi:10.1002/pmic.202400053
- Shakiba E, Pasdar Y, Asoudeh F, Najafi F, Saber A, et al. The relationship of dietary omega-3 fatty acid and omega-6 to omega-3 ratio intake and likelihood of type 2 diabetes in a cross-sectional study. BMC Endocr Disord. 2024;24:259. doi:10.1186/s12902-024-01787-y
- Liu C, Guo J, Guan L, Li C, Hu X, et al. Docosahexaenoic acid protects against ischemic stroke in diabetic mice by inhibiting inflammatory responses and apoptosis. Exp Neurol. 2025;385:115075. doi:10.1016/j.expneurol.2024.115075
- Bayat M, Koohpeyma F, Montazeri-Najafabady N, Dabbaghmanesh MH, Asmarian N, et al. The effects of modest intake of soy milk enriched with Lactobacillus casei and omega-3 on the testis parameters in diabetic rats: a stereological study. Int Urol Nephrol. 2025;57:1123. doi:10.1007/s11255-024-04243-x
- Xia J, Yin S, Yu J, Wang J, Jin X, et al. Improvement in Glycolipid Metabolism Parameters After Supplementing Fish Oil-Derived Omega-3 Fatty Acids Is Associated with Gut Microbiota and Lipid Metabolites in Type 2 Diabetes Mellitus. Nutrients. 2024;16. doi:10.3390/nu16213755
- Lamantia V, Bissonnette S, Beaudry M, Cyr Y, Rosiers CD, et al. EPA and DHA inhibit LDL-induced upregulation of human adipose tissue NLRP3 inflammasome/IL-1β pathway and its association with diabetes risk factors. Sci Rep. 2024;14:27146. doi:10.1038/s41598-024-73672-6
- Li J, Nan W, Huang X, Meng H, Wang S, et al. Eicosapentaenoic acid induces macrophage Mox polarization to prevent diabetic cardiomyopathy. EMBO Rep. 2024;25:5507. doi:10.1038/s44319-024-00271-x
- Schuchardt JP, Hahn A, Greupner T, Tintle NL, Westra J, et al. Higher docosahexaenoic acid proportions in blood are inversely associated with the prevalence of prediabetes: Evidence from the UK Biobank. Nutr Res. 2024;131:62. doi:10.1016/j.nutres.2024.09.009
- Rimmen EV, Mjøs SA, Søfteland E, Gudbrandsen OA. Intake of herring oil, but not of anchovy oil, resulted in a lower serum cholesterol concentration in male Zucker Diabetic Sprague Dawley rats. Br J Nutr. 2024;132:547. doi:10.1017/S0007114524001454
- Muzammil K, Khaleel AQ, Merza MS, Kyada A, Ariffin IA, et al. The effects of ω-3 fatty acids on inflammatory and oxidative stress markers in patients with Type 2 diabetes mellitus: A systematic review and meta-analysis of controlled trials. Prostaglandins Other Lipid Mediat. 2024;175:106887. doi:10.1016/j.prostaglandins.2024.106887
- Ao Y, Ye H, Liu X, Li Y, Liu H, et al. Fish oil supplementation in relation to the risk of chronic kidney disease among patients with diabetes. Diabetes Obes Metab. 2024;26:5283. doi:10.1111/dom.15880
