' 
SCIENTIFIC SCORE
Moderately Effective
Based on 24 Researches
8.2
USERS' SCORE
Excellent
Based on 143 Reviews
9
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Proprietary Probiotic Blend
134 mg (1 Billion CFU§)
†
Lactobacillus rhamnosus (GR-1®)
Lactobacillus reuteri (RC-14®)
Top Medical Research Studies
9
Lactobacillus rhamnosus shows promise
Lactobacillus rhamnosus intake can prevent the development of Candidiasis.
Relevant study on infection prevention
This study examined how Lactobacillus rhamnosus could impact the development of yeast infections, specifically candidiasis. By using immunosuppressed mice, we created various groups to see if taking this probiotic before or during Candida exposure made a difference.
The results were promising: the group that took the probiotic 14 days beforehand showed significantly lower levels of Candida. We also noted reduced inflammation in tissues from these mice. While some cytokine levels were lower across the board, the differences weren't statistically significant. Overall, lactobacillus rhamnosus appears to be a potentially effective preventive measure against yeast infections.
The results were promising: the group that took the probiotic 14 days beforehand showed significantly lower levels of Candida. We also noted reduced inflammation in tissues from these mice. While some cytokine levels were lower across the board, the differences weren't statistically significant. Overall, lactobacillus rhamnosus appears to be a potentially effective preventive measure against yeast infections.
Read More
9
L. reuteri shows antifungal potential
Limosilactobacillus reuteri 29A Cell-Free Supernatant Antibiofilm and Antagonistic Effects in Murine Model of Vulvovaginal Candidiasis.
High relevance for treatment options
We looked into how Lactobacillus reuteri 29A can combat yeast infections, specifically vulvovaginal candidiasis. The study examined its cell-free supernatant (CFS) for its ability to disrupt and inhibit biofilms formed by Candida species in both lab settings and in mice.
What we found was promising—the CFS effectively weakened established fungal biofilms and showed no harm to healthy tissues in mice. This suggests that L. reuteri could be a beneficial addition to treating or preventing vaginal yeast infections.
What we found was promising—the CFS effectively weakened established fungal biofilms and showed no harm to healthy tissues in mice. This suggests that L. reuteri could be a beneficial addition to treating or preventing vaginal yeast infections.
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8
Lactobacillus may aid yeast infection treatment
Anti-Candida activity of beneficial vaginal lactobacilli in in vitro assays and in a murine experimental model.
Moderate relevance score
We examined how lactobacilli, particularly Lactobacillus rhamnosus, impact the battle against yeast infections like vulvovaginal candidiasis (VVC). In our study, thirty strains were tested in the lab, revealing that some were effective at inhibiting Candida growth, mainly through organic acids.
In a murine model, the preventive-therapeutic use of L. rhamnosus showed significant promise, reducing fungal presence and associated inflammation. However, we found mixed results, as some testing methods showed no anti-Candida activity. Overall, lactobacilli could be beneficial, but more research is needed.
In a murine model, the preventive-therapeutic use of L. rhamnosus showed significant promise, reducing fungal presence and associated inflammation. However, we found mixed results, as some testing methods showed no anti-Candida activity. Overall, lactobacilli could be beneficial, but more research is needed.
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Most Useful Reviews
9.5
Chronic yeast infection relief
Kicked a chronic yeast infection! Instead of using antifungals, probiotics were my answer. I struggled for almost four months with a stubborn infection, tested for various conditions, but nothing helped. I previously used Culturelle without success for my yeast infection because it doesn't colonise the vaginal tract. Femdophilus is the game-changer—it has the right strains. After both oral and vaginal use, relief was almost immediate, and I plan to continue it long-term.
Read More
9.5
Significant health difference.
This is such a life saviour. After battling BV throughout my second pregnancy, I found that antibiotics were ineffective. Since starting these probiotics, I have seen a significant health improvement, along with dietary changes. If you're fighting BV or yeast infections, I urge you to try this; it can truly change your life!
Read More
9.5
No more infections
The capsules are small and easy to take. These are a true life saver! After battling constant yeast and bacterial infections for years, I decided to try this probiotic. I took it daily and, incredibly, I haven’t had an infection again for almost a year! I'm being proactive and purchased another bottle just in case. They’ve never upset my stomach, making them absolutely worth it!
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 24 Researches
8.2
- All Researches
9.5
Lactobacillus rhamnosus shows promise
Identification of sulfur components enhancing the anti-Candida effect of Lactobacillus rhamnosus Lcr35.
High relevance to yeast infections
We investigated how Lactobacillus rhamnosus Lcr35, contained in the GYNOPHILUS product, can combat yeast infections like Candida. This study showed that the product’s formulation, enhanced by sodium thiosulfate, improves its ability to kill yeast cells.
Remarkably, after 48 hours of co-culturing, the yeast’s viability dropped to zero. The presence of odor-active sulfur compounds, specifically S-methyl thioacetate, was linked to this antifungal effect.
Interestingly, achieving the full antifungal impact relies on these sulfur components.
Remarkably, after 48 hours of co-culturing, the yeast’s viability dropped to zero. The presence of odor-active sulfur compounds, specifically S-methyl thioacetate, was linked to this antifungal effect.
Interestingly, achieving the full antifungal impact relies on these sulfur components.
Read More
9
Lactobacillus rhamnosus shows promise
Anticandidal Activity of Various Probiotic Lactobacillus Strains and Their Efficacy Enhanced by Prebiotic Supplementation.
High relevance for Candida treatment.
We examined the effectiveness of various Lactobacillus strains, particularly Lactobacillus rhamnosus, against yeast infections caused by Candida. Through our analysis, we found that live probiotic cells and their cell-free supernatants showed strong anticandidal activity.
Notably, L. rhamnosus SD11 was especially effective, particularly when supplemented with prebiotics like mangosteen, leading to improved growth and metabolic activity. This suggests that combining probiotics and prebiotics might be a promising alternative treatment for Candida infections.
Notably, L. rhamnosus SD11 was especially effective, particularly when supplemented with prebiotics like mangosteen, leading to improved growth and metabolic activity. This suggests that combining probiotics and prebiotics might be a promising alternative treatment for Candida infections.
Read More
9
Probiotic shows potential against fungus
Lactobacillus rhamnosus Lcr35 as an effective treatment for preventing Candida albicans infection in the invertebrate model Caenorhabditis elegans: First mechanistic insights.
Relevant for antifungal strategies
We investigated the effectiveness of Lactobacillus rhamnosus Lcr35® against Candida albicans using lab models. The study showed that this probiotic significantly reduced fungal growth and adhesion in cell cultures.
In the nematode model, it helped improve worm survival rates, even against detectable yeast. The probiotic appeared to suppress the fungus's virulence while also activating the worm's immune responses. Overall, the findings suggest that Lcr35® could be a promising strategy for combatting yeast infections.
In the nematode model, it helped improve worm survival rates, even against detectable yeast. The probiotic appeared to suppress the fungus's virulence while also activating the worm's immune responses. Overall, the findings suggest that Lcr35® could be a promising strategy for combatting yeast infections.
Read More
9
Lactobacillus rhamnosus shows promise
Lactobacillus rhamnosus intake can prevent the development of Candidiasis.
Relevant study on infection prevention
This study examined how Lactobacillus rhamnosus could impact the development of yeast infections, specifically candidiasis. By using immunosuppressed mice, we created various groups to see if taking this probiotic before or during Candida exposure made a difference.
The results were promising: the group that took the probiotic 14 days beforehand showed significantly lower levels of Candida. We also noted reduced inflammation in tissues from these mice. While some cytokine levels were lower across the board, the differences weren't statistically significant. Overall, lactobacillus rhamnosus appears to be a potentially effective preventive measure against yeast infections.
The results were promising: the group that took the probiotic 14 days beforehand showed significantly lower levels of Candida. We also noted reduced inflammation in tissues from these mice. While some cytokine levels were lower across the board, the differences weren't statistically significant. Overall, lactobacillus rhamnosus appears to be a potentially effective preventive measure against yeast infections.
Read More
9
Potential ally against Candida infections
Immunomodulatory effects and anti-Candida activity of lactobacilli in macrophages and in invertebrate model of Galleria mellonella.
Highly relevant to fungal treatment
We explored how Lactobacillus rhamnosus (LR) can aid in fighting Candida infections. The study tested LR and other lactobacilli in both mouse macrophages and Galleria mellonella larvae.
Results showed that LR significantly boosted immune responses and enhanced larvae survival against Candida. In particular, it reduced yeast counts, showcasing its potential as an adjunct treatment for managing yeast infections.
Ultimately, LR stood out for its anti-Candida effects, making it a promising ally against these tough fungal threats.
Results showed that LR significantly boosted immune responses and enhanced larvae survival against Candida. In particular, it reduced yeast counts, showcasing its potential as an adjunct treatment for managing yeast infections.
Ultimately, LR stood out for its anti-Candida effects, making it a promising ally against these tough fungal threats.
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User Reviews
USERS' SCORE
Excellent
Based on 143 Reviews
9
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Chronic yeast infection relief
Kicked a chronic yeast infection! Instead of using antifungals, probiotics were my answer. I struggled for almost four months with a stubborn infection, tested for various conditions, but nothing helped. I previously used Culturelle without success for my yeast infection because it doesn't colonise the vaginal tract. Femdophilus is the game-changer—it has the right strains. After both oral and vaginal use, relief was almost immediate, and I plan to continue it long-term.
Read More
9.5
Significant health difference.
This is such a life saviour. After battling BV throughout my second pregnancy, I found that antibiotics were ineffective. Since starting these probiotics, I have seen a significant health improvement, along with dietary changes. If you're fighting BV or yeast infections, I urge you to try this; it can truly change your life!
Read More
9.5
No more infections
The capsules are small and easy to take. These are a true life saver! After battling constant yeast and bacterial infections for years, I decided to try this probiotic. I took it daily and, incredibly, I haven’t had an infection again for almost a year! I'm being proactive and purchased another bottle just in case. They’ve never upset my stomach, making them absolutely worth it!
Read More
9.5
Year-long infection resolved
Year-long yeast infection GONE! I had an ongoing yeast infection for almost a year caused by candida glabrata, resistant to most treatments. I utilized various remedies with no success. I finally began taking these probiotics and introduced a diet change while also using diflucan sporadically. Maintaining good hygiene helped too, and now, after two weeks, I’m infection-free. I’m continuing this regimen for maintenance, and I’m incredibly thankful to have finally dealt with the root cause of my recurrent yeast infection.
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9.5
Relief on third day
I wish I could give this more stars! Like many women here, I have experienced chronic yeast infections and BV issues, particularly while on antibiotics for Boils. After just three days of taking this product, I noticed a remarkable difference—no more itching and the funny odour is gone! I cannot express how happy I am; every woman knows how unsexy it feels when things aren't right down there. My confidence is regained, and I will definitely let other women know about this incredible product! However, I did notice I seemed to urinate more, but I’m not certain if that was due to the medication. I will be purchasing more!
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