Overview
SCIENTIFIC SCORE
Questionable
Based on 15 Researches
6.9
USERS' SCORE
Good
Based on 12 Reviews
8.7
Supplement Facts
Serving Size: 2 tablets
Amount Per Serving
%DV
Pancreatic EnzymesUsp Units Of Activity:Amylase 81,250 UspProtease 81,250 UspLipase 6,500 Usp
361 mg
**
Trypsin
75 mg
**
Papain
50 mg
**
Bromelain
16 mg
**
Amylase
10 mg
**
Lipase
10 mg
**
Chymotrypsin
2 mg
**
Top Medical Research Studies
8
We conducted a randomized double-blind trial to see if pancreatin could help prevent weight loss in patients with unresectable cancer of the pancreatic head region.
Over eight weeks, 21 patients received either pancreatin or a placebo, alongside dietary counseling.
Those on pancreatin gained weight, while placebo patients lost weight. The results showed a significant difference, suggesting that pancreatin may effectively counteract weight loss during this critical period.
Over eight weeks, 21 patients received either pancreatin or a placebo, alongside dietary counseling.
Those on pancreatin gained weight, while placebo patients lost weight. The results showed a significant difference, suggesting that pancreatin may effectively counteract weight loss during this critical period.
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2
We assessed the effectiveness of pancreatic exocrine replacement therapy (PERT) in preventing weight loss for patients with unresectable pancreatic cancer through a double-blind, randomized trial involving 67 participants.
Each patient received either pancreatin capsules or a placebo for eight weeks. However, the results showed no significant difference in weight loss between the two groups.
Additionally, there was no notable improvement in quality of life or overall survival rates, suggesting that PERT may not be beneficial in this context. Further research is needed to explore who might benefit from PERT.
Each patient received either pancreatin capsules or a placebo for eight weeks. However, the results showed no significant difference in weight loss between the two groups.
Additionally, there was no notable improvement in quality of life or overall survival rates, suggesting that PERT may not be beneficial in this context. Further research is needed to explore who might benefit from PERT.
Read More
9
We explored the potential cancer-fighting properties of lunasin, a peptide found in Soy Bowman Birk Inhibitor Concentrate (BBIC). Our research revealed that lunasin, alongside BBI, plays a significant role in preventing breast cancer.
When administered to mice with human breast cancer, lunasin showed a remarkable capability to reduce tumor rates by up to 49%. In contrast, BBI did not demonstrate any significant effect on tumor development.
This suggests lunasin is the key player in BBIC’s cancer-preventive properties, with BBI primarily serving to protect lunasin from being digested.
When administered to mice with human breast cancer, lunasin showed a remarkable capability to reduce tumor rates by up to 49%. In contrast, BBI did not demonstrate any significant effect on tumor development.
This suggests lunasin is the key player in BBIC’s cancer-preventive properties, with BBI primarily serving to protect lunasin from being digested.
Read More
Most Useful Reviews
9
Effective cancer treatment
79 people found this helpful
Great for digestion, a remarkable cancer treatment and preventative. These enzymes aid digestion and play a crucial role in cancer prevention or treatment. The cancer protein lining must be digested for the immune system to attack, and maintaining enzyme levels is vital. By taking these enzymes, you’re not only improving digestion but also equipping your body with a therapeutic army of enzymes targeting cancer cells. Advise those with cancer to try Apricot seeds that contain b17 to eradicate cancer effectively. Removing protein helps enzymes break down the cancer protein lining, allowing b17 to penetrate and kill cancer cells. Dismiss the naysayers; real stories affirm the healing power of apricot seeds. For anyone battling cancer, consider sharing this essential information.
Read More
9
Immune system support
16 people found this helpful
I took Mega-Zim instead of the German Wobenzym, and it has proven to be even better in terms of enzyme composition. I took 5 tablets four times a day for ten days. It played a crucial role in exposing cancer cells to my immune system, allowing it to fight effectively. I consumed Mega-Zim an hour before meals with warm water, specifically to enrich my blood with enzymes. The quality and results were excellent, and I highly recommend it.
Read More
9
Tumour shrinkage noted
15 people found this helpful
A very good product. I utilised it alongside an anti-cancer regimen, and it was the sole enzyme product I employed. Over a 30-day period, the tumour reduced from 3 cm to 1 cm. This was part of a more extensive protocol involving other supplements and an organic vegetable diet.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 15 Researches
6.9
- All Researches
9
We explored the potential cancer-fighting properties of lunasin, a peptide found in Soy Bowman Birk Inhibitor Concentrate (BBIC). Our research revealed that lunasin, alongside BBI, plays a significant role in preventing breast cancer.
When administered to mice with human breast cancer, lunasin showed a remarkable capability to reduce tumor rates by up to 49%. In contrast, BBI did not demonstrate any significant effect on tumor development.
This suggests lunasin is the key player in BBIC’s cancer-preventive properties, with BBI primarily serving to protect lunasin from being digested.
When administered to mice with human breast cancer, lunasin showed a remarkable capability to reduce tumor rates by up to 49%. In contrast, BBI did not demonstrate any significant effect on tumor development.
This suggests lunasin is the key player in BBIC’s cancer-preventive properties, with BBI primarily serving to protect lunasin from being digested.
Read More
9
We examined the impact of porcine pancreatic enzyme extracts (PPE) on human pancreatic cancer in mice. Mice with transplanted cancer cells received PPE in their drinking water. The results showed that those treated with PPE lived significantly longer and had smaller tumors compared to untreated mice.
Interestingly, while PPE helped improve survival and reduced tumor size, the study found no notable differences in certain tumor growth factors or cell death rates between the two groups. This suggests that the nutritional benefits of PPE contributed to the observed outcomes.
Interestingly, while PPE helped improve survival and reduced tumor size, the study found no notable differences in certain tumor growth factors or cell death rates between the two groups. This suggests that the nutritional benefits of PPE contributed to the observed outcomes.
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9
We examined how pancreatin and other treatments affect fat absorption in patients suffering from pancreatic steatorrhoea. Over 45 patients were divided into four groups and treated with various medications for two to four weeks.
Interestingly, patients receiving high-lipase pancreatin had a notable reduction in fat excretion, showing it was more effective than sodium bicarbonate and proton pump inhibitors. However, all treatments were beneficial for mild cases. For more severe conditions, a greater dose of pancreatin paired with an acid-reducing agent could be necessary.
Interestingly, patients receiving high-lipase pancreatin had a notable reduction in fat excretion, showing it was more effective than sodium bicarbonate and proton pump inhibitors. However, all treatments were beneficial for mild cases. For more severe conditions, a greater dose of pancreatin paired with an acid-reducing agent could be necessary.
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8
We evaluated the effects of protein hydrolysates from three medicinal plants—Matricaria chamomilla, Ziziphora clinopodioides, and Cressa cretica—on cancer cells. Our methodology involved extracting and partially purifying the proteins, followed by treatment with pancreatin.
We found that these hydrolysates displayed both cytotoxic and antioxidant properties. Particularly, C. cretica showed cytotoxic activity against breast cancer cells, although it did not affect healthy cells significantly.
While the results are promising, especially for M. chamomilla in terms of cancer cell suppression, we must note that further research is needed before we can consider these findings as concrete breakthroughs in cancer therapy.
We found that these hydrolysates displayed both cytotoxic and antioxidant properties. Particularly, C. cretica showed cytotoxic activity against breast cancer cells, although it did not affect healthy cells significantly.
While the results are promising, especially for M. chamomilla in terms of cancer cell suppression, we must note that further research is needed before we can consider these findings as concrete breakthroughs in cancer therapy.
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8
We designed a study to evaluate if porcine pancreatic extract could help manage pancreatic cancer in hamsters. The hamsters were put on a high-fat diet, and after developing insulin resistance, one group received the extract while the other group drank plain water.
After 43 weeks, we found that the hamsters treated with the extract had fewer pancreatic tumors and lower insulin levels compared to the control group. However, there was no significant difference in blood glucose levels. Overall, these findings suggest that porcine pancreatic extract may inhibit the growth of pancreatic cancer.
After 43 weeks, we found that the hamsters treated with the extract had fewer pancreatic tumors and lower insulin levels compared to the control group. However, there was no significant difference in blood glucose levels. Overall, these findings suggest that porcine pancreatic extract may inhibit the growth of pancreatic cancer.
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User Reviews
USERS' SCORE
Good
Based on 12 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective cancer treatment
79 people found this helpful
Great for digestion, a remarkable cancer treatment and preventative. These enzymes aid digestion and play a crucial role in cancer prevention or treatment. The cancer protein lining must be digested for the immune system to attack, and maintaining enzyme levels is vital. By taking these enzymes, you’re not only improving digestion but also equipping your body with a therapeutic army of enzymes targeting cancer cells. Advise those with cancer to try Apricot seeds that contain b17 to eradicate cancer effectively. Removing protein helps enzymes break down the cancer protein lining, allowing b17 to penetrate and kill cancer cells. Dismiss the naysayers; real stories affirm the healing power of apricot seeds. For anyone battling cancer, consider sharing this essential information.
Read More
9
Immune system support
16 people found this helpful
I took Mega-Zim instead of the German Wobenzym, and it has proven to be even better in terms of enzyme composition. I took 5 tablets four times a day for ten days. It played a crucial role in exposing cancer cells to my immune system, allowing it to fight effectively. I consumed Mega-Zim an hour before meals with warm water, specifically to enrich my blood with enzymes. The quality and results were excellent, and I highly recommend it.
Read More
9
Tumour shrinkage noted
15 people found this helpful
A very good product. I utilised it alongside an anti-cancer regimen, and it was the sole enzyme product I employed. Over a 30-day period, the tumour reduced from 3 cm to 1 cm. This was part of a more extensive protocol involving other supplements and an organic vegetable diet.
Read More
9
No digestive issues
5 people found this helpful
I often experience diarrhoea from enzymes, but these caused no problems at all. I felt much better after taking them, and they were recommended by my cancer options doctor.
Read More
9
Effective treatment support
2 people found this helpful
I purchased this drug as part of my treatment protocol. The enzymes have significantly improved my condition; bloating has ceased, and my stomach feels normal again. This product, with its high pancreatin content, is affordable and beneficial in cancer treatment.
Read More
Frequently Asked Questions
9
Immune system support
16 people found this helpful
I took Mega-Zim instead of the German Wobenzym, and it has proven to be even better in terms of enzyme composition. I took 5 tablets four times a day for ten days. It played a crucial role in exposing cancer cells to my immune system, allowing it to fight effectively. I consumed Mega-Zim an hour before meals with warm water, specifically to enrich my blood with enzymes. The quality and results were excellent, and I highly recommend it.
9
Effective treatment support
2 people found this helpful
I purchased this drug as part of my treatment protocol. The enzymes have significantly improved my condition; bloating has ceased, and my stomach feels normal again. This product, with its high pancreatin content, is affordable and beneficial in cancer treatment.
7.5
Dosage adjustment benefits
6 people found this helpful
I began with 2 tablets to test my body's reaction and increased to 6-8 daily. It's crucial to take these enzymes on an empty stomach, as they assist in combating cancer cells. I felt more energetic and found significant relief, especially after ensuring proper hydration. I do recommend avoiding cold water as it may drain energy, particularly when managing autoimmunity.
7.5
Energy restoration
1 people found this helpful
I started with 2 tablets and increased to 6-8 daily. Enzymes are most effective on an empty stomach for fighting cancer cells. After taking them, I had more energy and less pain despite my busy work schedule. A noticeable change in stool and smell occurred, but I managed well overall with no significant side effects.
9
Improved wellbeing
1 people found this helpful
I often have diarrhoea when taking enzymes, but these have caused no issues, leaving me feeling significantly better. They were also recommended by my cancer options doctor.
7
We explored the potential of peptides derived from soybean and cowpea proteins to inhibit breast and prostate cancer cell growth. After hydrolyzing these proteins with pancreatin, the resulting peptides showed promise in laboratory tests. Notably, one peptide, VIPAAY, demonstrated a strong ability to interact with the Bcl-2 protein, similar to a popular cancer drug called Venetoclax. However, while initial findings are encouraging, further research is necessary to confirm these results and understand their true impact on cancer treatment.
7
Jackfruit leaf hydrolysates reduce cancer cell viability
We evaluated how jackfruit leaf protein hydrolysates, produced using pepsin and pancreatin, affect cancer cells and oxidative stress. Our analysis revealed that these hydrolysates had peptide sizes ranging from 20 to 25 kDa. While we didn't observe significant toxicity on normal cells, the hydrolysates showed promising results in reducing cancer cell viability. Specifically, the 240-minute pancreatin hydrolysate reduced cervical cancer cell viability by 23%, along with notable reductions in ovarian and liver cancer cells. The hydrolysates also protected against oxidative stress, showcasing their potential for safe use in plant-based therapies.
7
We observed the promising effects of Kluyveromyces marxianus PCH397, a yeast strain derived from yak milk, on various health conditions. This study highlighted its strong probiotic traits, showing impressive survivability through digestive conditions.
Notably, it spurred insulin uptake in fat cells, which could aid in type 2 diabetes treatment. We also noted its ability to reduce lipid buildup and increase antioxidant activity. Importantly, the yeast's extracts appeared to effectively slow the growth of colorectal cancer cells, indicating its potential therapeutic role against obesity, diabetes, and cancer.
Notably, it spurred insulin uptake in fat cells, which could aid in type 2 diabetes treatment. We also noted its ability to reduce lipid buildup and increase antioxidant activity. Importantly, the yeast's extracts appeared to effectively slow the growth of colorectal cancer cells, indicating its potential therapeutic role against obesity, diabetes, and cancer.
9
We explored the potential cancer-fighting properties of lunasin, a peptide found in Soy Bowman Birk Inhibitor Concentrate (BBIC). Our research revealed that lunasin, alongside BBI, plays a significant role in preventing breast cancer.
When administered to mice with human breast cancer, lunasin showed a remarkable capability to reduce tumor rates by up to 49%. In contrast, BBI did not demonstrate any significant effect on tumor development.
This suggests lunasin is the key player in BBIC’s cancer-preventive properties, with BBI primarily serving to protect lunasin from being digested.
When administered to mice with human breast cancer, lunasin showed a remarkable capability to reduce tumor rates by up to 49%. In contrast, BBI did not demonstrate any significant effect on tumor development.
This suggests lunasin is the key player in BBIC’s cancer-preventive properties, with BBI primarily serving to protect lunasin from being digested.
References
- Philadelpho BO, Santiago VG, Santos JEMD, Silva MBCE, De Grandis RA, et al. Soybean β-Conglycinin and Cowpea β-Vignin Peptides Inhibit Breast and Prostate Cancer Cell Growth: An In Silico and In Vitro Approach. Foods. 2024;13. doi:10.3390/foods13213508
- Calderón-Chiu C, Ragazzo-Sánchez JA, Ordaz-Hernández A, Herrera-Martínez M. Jackfruit Leaf Protein Hydrolysates Obtained by Enzymatic Hydrolysis of Leaf Protein Concentrate with Pepsin and Pancreatin: Molecular Weight, Cytotoxicity, Antiproliferative Activity, and Oxidative Stress. Plant Foods Hum Nutr. 2024;79:685. doi:10.1007/s11130-024-01203-9
- Akbarmehr A, Peighambardoust SH, Ghanbarzadeh B, Sarabandi K. Physicochemical, antioxidant, antimicrobial, and in vitro cytotoxic activities of corn pollen protein hydrolysates obtained by different peptidases. Food Sci Nutr. 2023;11:2403. doi:10.1002/fsn3.3252
- Nag D, Goel A, Padwad Y, Singh D. In Vitro Characterisation Revealed Himalayan Dairy Kluyveromyces marxianus PCH397 as Potential Probiotic with Therapeutic Properties. Probiotics Antimicrob Proteins. 2023;15:761. doi:10.1007/s12602-021-09874-5
- Taghizadeh MS, Niazi A, Moghadam A, Afsharifar AR. The potential application of the protein hydrolysates of three medicinal plants: cytotoxicity and functional properties. J Food Sci. 2020;85:3160. doi:10.1111/1750-3841.15379
- Kim H, Yoon YS, Han Y, Kwon W, Kim SW, et al. Effects of Pancreatic Enzyme Replacement Therapy on Body Weight and Nutritional Assessments After Pancreatoduodenectomy in a Randomized Trial. Clin Gastroenterol Hepatol. 2020;18:926. doi:10.1016/j.cgh.2019.08.061
- Woo SM, Joo J, Kim SY, Park SJ, Han SS, et al. Efficacy of pancreatic exocrine replacement therapy for patients with unresectable pancreatic cancer in a randomized trial. Pancreatology. 2016;16:1099. doi:10.1016/j.pan.2016.09.001
- Nozawa F, Yalniz M, Saruc M, Standop J, Egami H, et al. Effects of porcine pancreatic enzymes on the pancreas of hamsters. Part 2: carcinogenesis studies. JOP. 2012;13:482. doi:10.6092/1590-8577/663
- Saruc M, Nozawa F, Yalniz M, Itami A, Pour PM. Effects of porcine pancreatic enzymes on the pancreas of hamsters. Part 1: basic studies. JOP. 2012;13:476. doi:10.6092/1590-8577/522
- Hsieh CC, Hernández-Ledesma B, Jeong HJ, Park JH, de Lumen BO. Complementary roles in cancer prevention: protease inhibitor makes the cancer preventive peptide lunasin bioavailable. PLoS One. 2010;5:e8890. doi:10.1371/journal.pone.0008890
- Saruc M, Standop S, Standop J, Nozawa F, Itami A, et al. Pancreatic enzyme extract improves survival in murine pancreatic cancer. Pancreas. 2004;28:401.
- Kriváchy P, Bálint A, Máté M, Ihász M. [Result of Panzytrat 25000 therapy following total gastrectomy]. Orv Hetil. 1999;140:2107.
- Bruno MJ, Haverkort EB, Tijssen GP, Tytgat GN, van Leeuwen DJ. Placebo controlled trial of enteric coated pancreatin microsphere treatment in patients with unresectable cancer of the pancreatic head region. Gut. 1998;42:92.
- Nakamura T, Takebe K, Kudoh K, Ishii M, Imamura K, et al. Effects of pancreatic digestive enzymes, sodium bicarbonate, and a proton pump inhibitor on steatorrhoea caused by pancreatic diseases. J Int Med Res. 1995;23:37.
- Zavadova E, Desser L, Mohr T. Stimulation of reactive oxygen species production and cytotoxicity in human neutrophils in vitro and after oral administration of a polyenzyme preparation. Cancer Biother. 1995;10:147.
