Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 47 Researches
7.4
USERS' SCORE
Good
Based on 3 Reviews
8.4
Supplement Facts
Serving Size: 2 Soft Gels
Amount Per Serving
%DV
Calories
20
Total Fat
2 g
3%
Saturated Fat
0 g
0%
Trans Fat
0 g
†
Vitamin D3 (cholecalciferol)
25 mcg (1000 IU)
125%
Total Omega-3s♦
1280 mg
†
EPA (Eicosapentaenoic Acid)
650 mg
†
DHA (Docosahexaenoic Acid)
450 mg
†
Top Medical Research Studies
8
We explored the impact of a high omega-3, low omega-6 diet with fish oil on men with prostate cancer under active surveillance. In a year-long study involving 100 participants, those following the omega-rich regimen showed a notable 15% decrease in the Ki-67 index, a key marker for cancer progression.
In contrast, the control group experienced an increase in this index. While the diet showed promise in slowing down potential cancer growth, no significant differences were noted in other cancer-related measurements. Our findings encourage further research on dietary strategies in prostate cancer management.
In contrast, the control group experienced an increase in this index. While the diet showed promise in slowing down potential cancer growth, no significant differences were noted in other cancer-related measurements. Our findings encourage further research on dietary strategies in prostate cancer management.
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8
We investigated the potential of vitamin D3, also known as cholecalciferol, in combating cancer while addressing concerns about its toxicity at higher doses. This study focused on enhancing the effectiveness of vitamin D3 through a clever method called liposomal encapsulation, which helps minimize side effects.
We prepared liposomal vitamin D3 (VD-LP) and conducted various tests to understand its capabilities. We found that this encapsulated form not only maintained high efficiency but also demonstrated improved stability. Our analyses showed that VD-LP had strong effects against cancer cells from colorectal, breast, and prostate cancers. Remarkably, it affected gene expression in immune cells, boosting elements that help fight infections and support the body's defenses.
Notably, VD-LP did a great job slowing tumor growth in mice and improved their survival rates without causing adverse effects like hypercalcemia, which is often a concern with regular vitamin D3 use. This evidence indicates that liposomal encapsulation of vitamin D3 could offer an effective cancer treatment strategy while minimizing unwanted side effects.
We believe this may pave the way for further research and clinical applications, showcasing vitamin D3 as a valuable addition to cancer therapy.
We prepared liposomal vitamin D3 (VD-LP) and conducted various tests to understand its capabilities. We found that this encapsulated form not only maintained high efficiency but also demonstrated improved stability. Our analyses showed that VD-LP had strong effects against cancer cells from colorectal, breast, and prostate cancers. Remarkably, it affected gene expression in immune cells, boosting elements that help fight infections and support the body's defenses.
Notably, VD-LP did a great job slowing tumor growth in mice and improved their survival rates without causing adverse effects like hypercalcemia, which is often a concern with regular vitamin D3 use. This evidence indicates that liposomal encapsulation of vitamin D3 could offer an effective cancer treatment strategy while minimizing unwanted side effects.
We believe this may pave the way for further research and clinical applications, showcasing vitamin D3 as a valuable addition to cancer therapy.
Read More
9
We explored the potential of omega-3 fatty acids in managing pancreatic cancer using a specially designed mouse model that closely mimics human disease. Our study found that a diet enriched with omega-3s significantly reduced tumor size, lung and liver metastasis, and even suggested improved survival rates when compared to controls.
Additionally, these fatty acids altered tumor composition and induced cancer cell death without hindering cell growth. Importantly, our research points to omega-3s as promising dietary interventions that could help tackle this aggressive cancer.
Additionally, these fatty acids altered tumor composition and induced cancer cell death without hindering cell growth. Importantly, our research points to omega-3s as promising dietary interventions that could help tackle this aggressive cancer.
Read More
Most Useful Reviews
9
Prevented recurrence
6 people found this helpful
Using for 10+ years. A wellness physician suggested these pills for my wellbeing. Every woman should take Vitamin D supplements, and I believe these are the best on the market. I had two rounds of breast cancer and have not experienced a recurrence since starting them.
Read More
7.5
Improved immunity
Twist promotes muscle tone, boosts immunity, and is essential for thyroid function and normal blood clotting. It also helps restore nerve membranes, regulates blood pressure, and prevents cancer cell growth.
Read More
6
Cancer prevention
Norm aids the body in restoring protective membranes around the nerves, regulates blood pressure and heartbeat, and prevents the growth of cancer cells.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 47 Researches
7.4
- All Researches
9.5
Omega-3 fatty acids inhibit tumors
We conducted a study to explore the effects of high doses of omega-3 fatty acids—specifically eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)—on tumor formation in a model of neuroblastoma, a challenging pediatric cancer. Using a syngeneic mouse model, we administered these fatty acids at doses equivalent to those safely tolerable in humans.
After the gavage, we introduced neuro-2a cells that were prone to tumor development. Our observations revealed that both DHA and EPA completely halted tumor formation in the treated mice, in stark contrast to the control group where half of the mice did develop tumors. Intriguingly, we also noticed that arachidonic acid (another fatty acid) actually promoted tumor growth, suggesting that it might counteract the positive effects of EPA.
Overall, these findings indicate that ultra-high doses of omega-3 fatty acids, particularly DHA and EPA, could offer a promising, low-toxicity treatment for neuroblastoma by blocking tumorigenesis. This research highlights the potential for incorporating dietary fatty acids into cancer therapies, especially for high-risk pediatric patients who currently face limited options.
After the gavage, we introduced neuro-2a cells that were prone to tumor development. Our observations revealed that both DHA and EPA completely halted tumor formation in the treated mice, in stark contrast to the control group where half of the mice did develop tumors. Intriguingly, we also noticed that arachidonic acid (another fatty acid) actually promoted tumor growth, suggesting that it might counteract the positive effects of EPA.
Overall, these findings indicate that ultra-high doses of omega-3 fatty acids, particularly DHA and EPA, could offer a promising, low-toxicity treatment for neuroblastoma by blocking tumorigenesis. This research highlights the potential for incorporating dietary fatty acids into cancer therapies, especially for high-risk pediatric patients who currently face limited options.
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9
We explored the potential of omega-3 fatty acids in managing pancreatic cancer using a specially designed mouse model that closely mimics human disease. Our study found that a diet enriched with omega-3s significantly reduced tumor size, lung and liver metastasis, and even suggested improved survival rates when compared to controls.
Additionally, these fatty acids altered tumor composition and induced cancer cell death without hindering cell growth. Importantly, our research points to omega-3s as promising dietary interventions that could help tackle this aggressive cancer.
Additionally, these fatty acids altered tumor composition and induced cancer cell death without hindering cell growth. Importantly, our research points to omega-3s as promising dietary interventions that could help tackle this aggressive cancer.
Read More
We investigated the role of alpha-linolenic acid (ALA), a plant-based omega-3 found in perilla seed oil, in preventing colitis-associated colorectal cancer (CRC) using a mouse model.
Mice were given different diets, while only the control group received soybean oil.
The results showed that those on a 5% perilla seed oil diet had fewer tumors and lower markers of inflammation compared to those on fish oil or soybean oil.
Overall, perilla seed oil appeared to help slow tumor progression and restore gut health.
Mice were given different diets, while only the control group received soybean oil.
The results showed that those on a 5% perilla seed oil diet had fewer tumors and lower markers of inflammation compared to those on fish oil or soybean oil.
Overall, perilla seed oil appeared to help slow tumor progression and restore gut health.
Read More
9
Vitamin D3 derivatives improve cancer treatment
We focused on how modified forms of vitamin D3 can positively affect cancer treatment. The study revealed that a specific derivative, known as MART-10, demonstrated significant anti-tumor effects in mouse models. When administered at low doses, this compound showed robust anti-cancer activity against BxpC-3 cancer cells.
Additionally, we explored a new vitamin D analog, AH-1, which was found to enhance bone formation without the usual side effects associated with vitamin D treatments. This is particularly promising for osteoporosis patients. Another derivative named NS-74c even exhibited potent antagonist activity against the vitamin D receptor, indicating a potential for varied therapeutic uses.
Overall, our research highlighted the potential of vitamin D3 derivatives to tackle cancer while minimizing adverse effects. This approach opens new doors for therapeutic options in oncology, providing a glimpse into how modified vitamin D can improve treatment outcomes for patients.
Additionally, we explored a new vitamin D analog, AH-1, which was found to enhance bone formation without the usual side effects associated with vitamin D treatments. This is particularly promising for osteoporosis patients. Another derivative named NS-74c even exhibited potent antagonist activity against the vitamin D receptor, indicating a potential for varied therapeutic uses.
Overall, our research highlighted the potential of vitamin D3 derivatives to tackle cancer while minimizing adverse effects. This approach opens new doors for therapeutic options in oncology, providing a glimpse into how modified vitamin D can improve treatment outcomes for patients.
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9
We developed a special hydrogel that mixes different components including eicosapentaenoic acid (EPA) to study its effects on cancer treatment. The hydrogel helps target the tumor environment more effectively due to its unique structure.
In our exploration, we noted that this hydrogel encouraged processes like lipid peroxidation and the production of reactive oxygen species, which are known to trigger a type of cell death called ferroptosis. Additionally, it promoted apoptosis, another way cancer cells can die, and supported an immune response in the tumor area.
As we observed, the hydrogel not only worked well in laboratory tests but also showed significant promise in reducing both primary tumors and metastatic growth in live models. This suggests that EPA can play a notable role when combined with innovative treatments, paving the way for better immune responses against tumors.
However, it is essential to highlight that since the study combined EPA with multiple components, isolating its individual impact might be challenging. Thus, while our findings are promising, we must approach the specific benefits of EPA cautiously as part of this comprehensive treatment strategy.
In our exploration, we noted that this hydrogel encouraged processes like lipid peroxidation and the production of reactive oxygen species, which are known to trigger a type of cell death called ferroptosis. Additionally, it promoted apoptosis, another way cancer cells can die, and supported an immune response in the tumor area.
As we observed, the hydrogel not only worked well in laboratory tests but also showed significant promise in reducing both primary tumors and metastatic growth in live models. This suggests that EPA can play a notable role when combined with innovative treatments, paving the way for better immune responses against tumors.
However, it is essential to highlight that since the study combined EPA with multiple components, isolating its individual impact might be challenging. Thus, while our findings are promising, we must approach the specific benefits of EPA cautiously as part of this comprehensive treatment strategy.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Prevented recurrence
6 people found this helpful
Using for 10+ years. A wellness physician suggested these pills for my wellbeing. Every woman should take Vitamin D supplements, and I believe these are the best on the market. I had two rounds of breast cancer and have not experienced a recurrence since starting them.
Read More
7.5
Improved immunity
Twist promotes muscle tone, boosts immunity, and is essential for thyroid function and normal blood clotting. It also helps restore nerve membranes, regulates blood pressure, and prevents cancer cell growth.
Read More
6
Cancer prevention
Norm aids the body in restoring protective membranes around the nerves, regulates blood pressure and heartbeat, and prevents the growth of cancer cells.
Read More
Frequently Asked Questions
7.5
Improved immunity
Twist promotes muscle tone, boosts immunity, and is essential for thyroid function and normal blood clotting. It also helps restore nerve membranes, regulates blood pressure, and prevents cancer cell growth.
6
Cancer prevention
Norm aids the body in restoring protective membranes around the nerves, regulates blood pressure and heartbeat, and prevents the growth of cancer cells.
9
We explored the potential of omega-3 fatty acids in managing pancreatic cancer using a specially designed mouse model that closely mimics human disease. Our study found that a diet enriched with omega-3s significantly reduced tumor size, lung and liver metastasis, and even suggested improved survival rates when compared to controls.
Additionally, these fatty acids altered tumor composition and induced cancer cell death without hindering cell growth. Importantly, our research points to omega-3s as promising dietary interventions that could help tackle this aggressive cancer.
Additionally, these fatty acids altered tumor composition and induced cancer cell death without hindering cell growth. Importantly, our research points to omega-3s as promising dietary interventions that could help tackle this aggressive cancer.
7
Omega-3s may reduce cancer risk
We examined the connection between omega-3 fatty acids in the blood and the risk of colorectal cancer among UK Biobank participants. Our analysis showed that higher levels of omega-3s were linked to a decreased risk of developing colorectal cancer, especially in males and for proximal colon cancers.
Interestingly, the relationship was nonlinear, suggesting that benefits plateau at higher omega-3 concentrations. This study could influence nutritional guidelines if our findings are supported by further research in various populations.
Interestingly, the relationship was nonlinear, suggesting that benefits plateau at higher omega-3 concentrations. This study could influence nutritional guidelines if our findings are supported by further research in various populations.
8
We examined the relationship between docosahexaenoic acid (DHA) and the risk of developing non-small cell lung cancer (NSCLC) through an extensive analysis of 249,132 participants over an average of 12 years. This large-scale, prospective study aimed to shed light on how different fatty acids, particularly DHA, might influence cancer risk.
During the follow-up, we learned that 1,460 participants were diagnosed with NSCLC. Our findings revealed that higher levels of DHA, along with linoleic acid (LA) and omega-3 fatty acids, were linked to a lower risk of developing this form of cancer. We found that increased concentrations of both DHA and LA appeared to significantly delay the onset of NSCLC.
Additionally, our analysis suggested that the relationship between these fatty acids and cancer risk varied among different groups based on factors like smoking status, gender, and body mass index. These findings provide promising insights into how dietary adjustments involving specific fatty acids could potentially lower the risk of NSCLC.
During the follow-up, we learned that 1,460 participants were diagnosed with NSCLC. Our findings revealed that higher levels of DHA, along with linoleic acid (LA) and omega-3 fatty acids, were linked to a lower risk of developing this form of cancer. We found that increased concentrations of both DHA and LA appeared to significantly delay the onset of NSCLC.
Additionally, our analysis suggested that the relationship between these fatty acids and cancer risk varied among different groups based on factors like smoking status, gender, and body mass index. These findings provide promising insights into how dietary adjustments involving specific fatty acids could potentially lower the risk of NSCLC.
7
We conducted a systematic review to evaluate how omega-3 supplementation affects the nutritional status of patients with pancreatic cancer. By examining multiple clinical trials, we found that omega-3s are generally safe and well-tolerated.
Most studies indicated that these supplements can help stabilize or increase body weight and reduce inflammation. This suggests that omega-3 fish oil may provide crucial support for those battling pancreatic cancer, enhancing their overall well-being.
Most studies indicated that these supplements can help stabilize or increase body weight and reduce inflammation. This suggests that omega-3 fish oil may provide crucial support for those battling pancreatic cancer, enhancing their overall well-being.
8
We examined the impact of omega-3 fish oil on chemotherapy-induced peripheral neuropathy (CIPN) in mice. Our findings indicate that this fish oil supplementation effectively prevented hypersensitivity caused by common chemotherapy drugs.
Over 30 days, it reduced neuroinflammation, which seems to be a key factor in mitigating pain and discomfort linked to treatments like paclitaxel and oxaliplatin.
By normalizing certain biochemical parameters, omega-3 fish oil holds potential to enhance the quality of life for cancer survivors facing CIPN.
Over 30 days, it reduced neuroinflammation, which seems to be a key factor in mitigating pain and discomfort linked to treatments like paclitaxel and oxaliplatin.
By normalizing certain biochemical parameters, omega-3 fish oil holds potential to enhance the quality of life for cancer survivors facing CIPN.
References
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- Melato J, Goldoni FC, Benvenutti L, Corrêa TP, Remor AP, et al. Omega-3-Enriched Fish oil reduces the chemotherapy-induced peripheral neuropathy in mice. Neuropharmacology. 2025;271:110384. 10.1016/j.neuropharm.2025.110384
- Cheniti H, Kadi A, Agred R, Kadi Y, Djeradi MK, et al. Fish Oil's Preventive Effect on Two-Stage Skin Carcinogenesis in Swiss Albino Mice: Involvement of NF-ҝB Pathways and Oxidative Stress in a Dose- and Route Dependent Manner. Mol Nutr Food Res. 2025;69:e202400630. 10.1002/mnfr.202400630
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- Garay MI, Mazo T, Ferrero V, Barotto NN, Lagares C, et al. Novel inhibitory effect of Omega-3 fatty acids regulating pancreatic cancer progression. Carcinogenesis. 2025;46. 10.1093/carcin/bgae081
- Aldoori J, Zulyniak MA, Toogood GJ, Hull MA. Plasma n-3 Polyunsaturated Fatty Acid Levels and Colorectal Cancer Risk in the UK Biobank: Evidence of Nonlinearity, as Well as Tumor Site- and Sex-Specificity. Cancer Epidemiol Biomarkers Prev. 2025;34:394. 10.1158/1055-9965.EPI-24-1154
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- Almassri HF, Abdul Kadir A, Srour M, Foo LH. The effects of Omega-3 fatty acids and vitamin D supplementation on the quality of life and blood inflammation markers in newly diagnosed breast cancer women: An open-labelled randomised controlled trial. Clin Nutr ESPEN. 2025;65:64. 10.1016/j.clnesp.2024.11.014
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- Machuca J, Wirkus J, Ead AS, Vahmani P, Matsukuma KE, et al. Dietary ω-3 Fatty Acids Mitigate Intestinal Barrier Integrity Alterations in Mice Fed a High-Fat Diet: Implications for Pancreatic Carcinogenesis. J Nutr. 2025;155:197. 10.1016/j.tjnut.2024.10.054
- Zhang Y, Sun Y, Song S, Khankari NK, Brenna JT, et al. Associations of plasma omega-6 and omega-3 fatty acids with overall and 19 site-specific cancers: A population-based cohort study in UK Biobank. Int J Cancer. 2025;156:1154. 10.1002/ijc.35226
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- Xu N, Lin H, Ding X, Wang P, Lin JM. Isotope tracing-assisted chip-based solid-phase extraction mass spectrometry for monitoring metabolic changes and vitamin D3 regulation in cells. Talanta. 2025;288:127754. 10.1016/j.talanta.2025.127754
- Jo Y, Kushram P, Bose S. Curcumin and vitamin D3 release from calcium phosphate enhances bone regeneration. Biomater Sci. 2025. 10.1039/d4bm01188k
- Ezcurra-Hualde M, Zalba S, Bella Á, Arrizabalaga L, Risson A, et al. Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Front Immunol. 2025;16:1529007. 10.3389/fimmu.2025.1529007
- Wang L, Xu R, Wang M, Wang M, Su S, et al. Exploration and Identification of Vitamin D and Related Genes as Potential Biomarkers for Colorectal Tumors. Onco Targets Ther. 2025;18:129. 10.2147/OTT.S495066
- Evans H, Greenhough A, Perry L, Lasanta G, Gonzalez CM, et al. Hypoxia Compromises the Differentiation of Human Osteosarcoma Cells to CAR-R, a Hydroxylated Derivative of Lithocholic Acid and Potent Agonist of the Vitamin D Receptor. Int J Mol Sci. 2025;26. 10.3390/ijms26010365
- Kittaka A. Synthetic Studies on Vitamin D Derivatives with Diverse but Selective Biological Activities. Chem Pharm Bull (Tokyo). 2025;73:1. 10.1248/cpb.c24-00598
- He W, Lv W, Liu L, Gong Y, Song K, et al. Enhanced Antiglioma Effect by a Vitamin D3-Inserted Lipid Hybrid Neutrophil Membrane Biomimetic Multimodal Nanoplatform. ACS Nano. 2024;18:35559. 10.1021/acsnano.4c13470
- Maturana-Ramiìrez A, Aitken-Saavedra J, Rojas-Zúñiga G, Rojas-Alcayaga G, Espinoza-Santander I, et al. Hypovitaminosis D in patients with oral squamous cell carcinoma: Is a risk factor of developing this neoplasia?. Med Oral Patol Oral Cir Bucal. 2025;30:e24. 10.4317/medoral.26692
- García-Martínez JM, Chocarro-Calvo A, Martínez-Useros J, Regueira-Acebedo N, Fernández-Aceñero MJ, et al. SIRT1 Mediates the Antagonism of Wnt/β-Catenin Pathway by Vitamin D in Colon Carcinoma Cells. Int J Biol Sci. 2024;20:5495. 10.7150/ijbs.95875
- Elçi MP, Fatsa T, Ören S, Miser Salihoğlu E, Akaydın S. Investigation of the Effects of Polyunsaturated Fatty Acid Ratios in Human SH-SY5Y Cells by Methods. Turk J Pharm Sci. 2025;22:10. 10.4274/tjps.galenos.2024.40583
- Babaeenezhad E, Khosravi P, Moradi Sarabi M. Dietary polyunsaturated fatty acids affect PPARγ promoter methylation status and regulate the PPARγ/COX2 pathway in some colorectal cancer cell lines. Genes Nutr. 2025;20:2. 10.1186/s12263-025-00764-x
- Patel V, Li YN, Benhamou LE, Park HG, Raleigh M, et al. Ultra-High Dose Oral ω3 Eicosapentaenoic Acid (EPA), Docosahexaenoic Acid (DHA), or Oxidation-Resistant Deuterated DHA Block Tumorigenesis in a -Driven Neuroblastoma Model. Cancers (Basel). 2025;17. 10.3390/cancers17030362
- Alharthy FH, Alsughayyir J, Alfhili MA. Eicosapentaenoic Acid Triggers Phosphatidylserine Externalization in the Erythrocyte Membrane through Calcium Signaling and Anticholinesterase Activity. Physiol Res. 2024;73:1075.
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- Frankhouser DE, DeWess T, Snodgrass IF, Cole RM, Steck S, et al. Randomized dose-response trial of n-3 fatty acids in hormone receptor negative breast cancer survivors- impact on breast adipose oxylipin and DNA methylation patterns. medRxiv. 2024. 10.1101/2024.09.16.24313691
- Ormiston K, Fitzgerald J, Andridge R, Lustberg MB, DeVries AC, et al. Low sucrose diets protect long-term memory and EPA & DHA enriched diets alter insulin resistance in a mouse model of chemotherapy. Nutr Res. 2024;131:39. 10.1016/j.nutres.2024.09.004
- Ormiston K, Melink Z, Andridge R, Lustberg M, Courtney DeVries A, et al. Dietary EPA and DHA enrichment of a high fat diet during doxorubicin-based chemotherapy attenuated neuroinflammatory gene expression in the brain of C57bl/6 ovariectomized mice. Brain Behav Immun. 2025;123:370. 10.1016/j.bbi.2024.09.021
- Chua AV, Hernandez ARB, Mendoza MJL, San Juan MD. Omega-3 Fatty Acids Increase Weight and Quality of Life Scores in Patients With Advanced Non-Small Cell Lung Cancer and Cancer Cachexia: A Meta-Analysis. Integr Cancer Ther. 2024;23:15347354241275052. 10.1177/15347354241275052
- Virani S, Afreen S, Perthiani A, Sangster E, Lanka N, et al. The Impact of Dietary Unsaturated Fat or the Mediterranean Diet on Women Diagnosed With Breast Cancer: A Systematic Review. Cureus. 2024;16:e65362. 10.7759/cureus.65362
- Gholamalizadeh M, Tajadod S, Majidi N, Aghakhaninejad Z, Mahmoudi Z, et al. Associations between diet and nutritional supplements and colorectal cancer: A systematic review. JGH Open. 2024;8:e13108. 10.1002/jgh3.13108
- Chen X, Jiang T, Li Y, Zhang Y, Chen J, et al. Carrageenan-ferrocene-eicosapentaenoic acid composite hydrogel induce ferroptosis and apoptosis for anti-tumor recurrence and metastasis. Int J Biol Macromol. 2024;276:133942. 10.1016/j.ijbiomac.2024.133942
- Babar MU, Nassar AF, Nie X, Zhang T, He J, et al. Is Lipid Metabolism of Value in Cancer Research and Treatment? Part II: Role of Specialized Pro-Resolving Mediators in Inflammation, Infections, and Cancer. Metabolites. 2024;14. 10.3390/metabo14060314
- Zhang Z, Zhou Q, Li Z, Huang F, Mo K, et al. DTX2 attenuates Lenvatinib-induced ferroptosis by suppressing docosahexaenoic acid biosynthesis through HSD17B4-dependent peroxisomal β-oxidation in hepatocellular carcinoma. Drug Resist Updat. 2025;81:101224. 10.1016/j.drup.2025.101224
- Teng Y, Luo C, Qiu X, Mu J, Sriwastva MK, et al. Plant-nanoparticles enhance anti-PD-L1 efficacy by shaping human commensal microbiota metabolites. Nat Commun. 2025;16:1295. 10.1038/s41467-025-56498-2
- Wang X, Ishimatsu K, Li J, Wen X, Ou W, et al. APT imaging of hepatocellular carcinoma signals an effective therapeutic response in advance of tumor shrinkage. Hepat Oncol. 2024;11:2389031. 10.1080/20450923.2024.2389031
- Olkhovik DM, Silkina MO, Razumovskaya AV, Klycheva KV, Fatkulin AA, et al. Omega-3 Docosahexaenoic Acid as a Promising Inducer of Ferroptosis: Dynamics of Action in Prostate and Colorectal Cancer Models. Dokl Biochem Biophys. 2025. 10.1134/S160767292460132X
- Lin HL, Lin QY, Feng JN, Zheng WE, Yang C, et al. Plasma fatty acid levels and risk of non-small cell lung cancer: a large-scale prospective cohort study. Front Nutr. 2024;11:1462300. 10.3389/fnut.2024.1462300
- La Vecchia S, Fontana S, Salaroglio IC, Anobile DP, Digiovanni S, et al. Increasing membrane polyunsaturated fatty acids sensitizes non-small cell lung cancer to anti-PD-1/PD-L1 immunotherapy. Cancer Lett. 2024;604:217221. 10.1016/j.canlet.2024.217221
- Huang J, Li J, He L, Miao J, Zhu M, et al. The association between plasma fatty acids and risk of lung cancer: a prospective cohort study of the UK Biobank. J Clin Endocrinol Metab. 2024. 10.1210/clinem/dgae609
- Lin SC, Tsai YC, Chen YL, Lin HK, Huang YC, et al. Un-methylation of NUDT21 represses docosahexaenoic acid biosynthesis contributing to enzalutamide resistance in prostate cancer. Drug Resist Updat. 2024;77:101144. 10.1016/j.drup.2024.101144
