Last update
4/18/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
USERS' SCORE
Good
Based on 18 Reviews
8.1
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Calories
5
Total Carbohydrate
1 g
<1%**
Milk Thistle Extract (Silybum marianum)(Fruit/Seeds) (Standardized to 240 mg Silymarin Flavonoids - equivalent 80%)
300 mg
†
Turmeric (Curcuma longa) (Root)
700 mg
†
Top Medical Research Studies
8
We explored the potential of intravenous silibinin, a milk thistle extract, in treating an HIV-HCV coinfected patient who didn't respond to standard therapy. After just two weeks of silibinin treatment, both HCV and HIV levels became undetectable.
While silibinin appeared promising, leading to a trend of increased CD4+ cells, the follow-up showed that HIV levels returned to their previous state after stopping additional therapy.
These findings suggest that while silibinin may help some, more research is needed to understand its benefits fully.
While silibinin appeared promising, leading to a trend of increased CD4+ cells, the follow-up showed that HIV levels returned to their previous state after stopping additional therapy.
These findings suggest that while silibinin may help some, more research is needed to understand its benefits fully.
Read More
8
We directly evaluated the effects of silymarin, or milk thistle extract, on hepatitis C virus (HCV) infection and liver protection.
Our study found that while silymarin does show some promise in reducing oxidative stress and inflammation, it didn't consistently surpass the potency of its individual flavonolignan compounds in battling the virus.
Overall, these findings indicate that silymarin-derived compounds could influence the progression of HCV in certain patients.
However, further research is needed to pinpoint clinical outcomes with standardized doses.
Our study found that while silymarin does show some promise in reducing oxidative stress and inflammation, it didn't consistently surpass the potency of its individual flavonolignan compounds in battling the virus.
Overall, these findings indicate that silymarin-derived compounds could influence the progression of HCV in certain patients.
However, further research is needed to pinpoint clinical outcomes with standardized doses.
Read More
4
We examined the use of silymarin, a popular herbal extract from milk thistle, among participants in the HALT-C Trial, focused on individuals with chronic hepatitis C. Our findings indicated that while many people were eager to utilize silymarin hoping to enhance treatment outcomes, there was no significant effect on liver enzyme levels or hepatitis C virus activity.
However, those taking silymarin reported fewer symptoms and somewhat better quality of life. Ultimately, since this study was observational, we believe more rigorous research is necessary to conclusively determine the benefits of silymarin for hepatitis C patients.
However, those taking silymarin reported fewer symptoms and somewhat better quality of life. Ultimately, since this study was observational, we believe more rigorous research is necessary to conclusively determine the benefits of silymarin for hepatitis C patients.
Read More
Most Useful Reviews
8
Protects liver cells
15 people found this helpful
Silymarin helps reduce damage in the liver caused by medications, protects against toxins, and addresses fatty liver. After using it for some time, I noticed impressive results in my liver health.
Read More
7
Improves liver function
3 people found this helpful
This drug is effective for treating acute or chronic hepatitis, liver cirrhosis, and digestive disorders. However, be cautious if you have high bilirubin or gallstones. The bitterness in the mouth and heaviness in the side diminish, and liver enzyme levels improve. Starting with one tablet before meals is recommended, gradually increasing as needed.
Read More
7
Supports liver health
3 people found this helpful
Milk thistle is beneficial for your liver! The formulation combining turmeric and milk thistle is excellent. I undertake a two-month course multiple times yearly. It cleanses blood vessels and eliminates toxins from the body, proving beneficial for many, especially for hepatitis and obesity. Milk thistle boasts anti-inflammatory and antioxidant properties, lowers blood sugar, and stimulates bile production.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
- All Researches
8
We explored the potential of intravenous silibinin, a milk thistle extract, in treating an HIV-HCV coinfected patient who didn't respond to standard therapy. After just two weeks of silibinin treatment, both HCV and HIV levels became undetectable.
While silibinin appeared promising, leading to a trend of increased CD4+ cells, the follow-up showed that HIV levels returned to their previous state after stopping additional therapy.
These findings suggest that while silibinin may help some, more research is needed to understand its benefits fully.
While silibinin appeared promising, leading to a trend of increased CD4+ cells, the follow-up showed that HIV levels returned to their previous state after stopping additional therapy.
These findings suggest that while silibinin may help some, more research is needed to understand its benefits fully.
Read More
8
We directly evaluated the effects of silymarin, or milk thistle extract, on hepatitis C virus (HCV) infection and liver protection.
Our study found that while silymarin does show some promise in reducing oxidative stress and inflammation, it didn't consistently surpass the potency of its individual flavonolignan compounds in battling the virus.
Overall, these findings indicate that silymarin-derived compounds could influence the progression of HCV in certain patients.
However, further research is needed to pinpoint clinical outcomes with standardized doses.
Our study found that while silymarin does show some promise in reducing oxidative stress and inflammation, it didn't consistently surpass the potency of its individual flavonolignan compounds in battling the virus.
Overall, these findings indicate that silymarin-derived compounds could influence the progression of HCV in certain patients.
However, further research is needed to pinpoint clinical outcomes with standardized doses.
Read More
4
We examined the use of silymarin, a popular herbal extract from milk thistle, among participants in the HALT-C Trial, focused on individuals with chronic hepatitis C. Our findings indicated that while many people were eager to utilize silymarin hoping to enhance treatment outcomes, there was no significant effect on liver enzyme levels or hepatitis C virus activity.
However, those taking silymarin reported fewer symptoms and somewhat better quality of life. Ultimately, since this study was observational, we believe more rigorous research is necessary to conclusively determine the benefits of silymarin for hepatitis C patients.
However, those taking silymarin reported fewer symptoms and somewhat better quality of life. Ultimately, since this study was observational, we believe more rigorous research is necessary to conclusively determine the benefits of silymarin for hepatitis C patients.
Read More
User Reviews
USERS' SCORE
Good
Based on 18 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
8
Protects liver cells
15 people found this helpful
Silymarin helps reduce damage in the liver caused by medications, protects against toxins, and addresses fatty liver. After using it for some time, I noticed impressive results in my liver health.
Read More
7
Improves liver function
3 people found this helpful
This drug is effective for treating acute or chronic hepatitis, liver cirrhosis, and digestive disorders. However, be cautious if you have high bilirubin or gallstones. The bitterness in the mouth and heaviness in the side diminish, and liver enzyme levels improve. Starting with one tablet before meals is recommended, gradually increasing as needed.
Read More
7
Supports liver health
3 people found this helpful
Milk thistle is beneficial for your liver! The formulation combining turmeric and milk thistle is excellent. I undertake a two-month course multiple times yearly. It cleanses blood vessels and eliminates toxins from the body, proving beneficial for many, especially for hepatitis and obesity. Milk thistle boasts anti-inflammatory and antioxidant properties, lowers blood sugar, and stimulates bile production.
Read More
7
Facilitates digestion
1 people found this helpful
Excellent digestion! Having suffered from hepatitis for years, Silymarin has allowed me to function normally regarding my digestion and bowel movements.
Read More
9
Alleviates spasms
I find the Now Foods Silymarin supplement a "magic wand" during gastrointestinal flare-ups. It improves liver function, detoxes the body, and significantly alleviates spasms linked to hepatitis and other conditions.
Read More
Frequently Asked Questions
9
No more fatty hepatitis
I had fatty hepatitis in my liver, but after prolonged, regular use, ultrasound confirmed it was no longer present.
9
Essential family purchase
Rescue for individuals experiencing liver and biliary tract issues. I previously took pharmacy chophytol, which is rather costly with scanty dosages. My aunt suffers from medicinal hepatitis following polychemotherapy, and silymarin has aided in normalising her liver parameters, allowing her to continue her treatment course. This has become a staple purchase in my family!
8
Protects liver cells
15 people found this helpful
Silymarin helps reduce damage in the liver caused by medications, protects against toxins, and addresses fatty liver. After using it for some time, I noticed impressive results in my liver health.
7
Supports liver health
This product is particularly useful for liver support. I use it because I had hepatitis C, and my doctor highly recommended it. It's the best supplement for individuals who consume excessive alcohol or take various medications. It aids detoxification for the liver and the entire body. The capsules are small and flavourless.
9
Improved liver function
Great complex! I ordered it for my husband to support his liver, as he had hepatitis A in childhood. We constantly help his liver and gallbladder. It works well, especially combined with turmeric, a powerful anti-inflammatory agent! His eyes are white again! We make regular purchases!
References
- Payer BA, Reiberger T, Rutter K, Beinhardt S, Staettermayer AF, et al. Successful HCV eradication and inhibition of HIV replication by intravenous silibinin in an HIV-HCV coinfected patient. J Clin Virol. 2010;49:131. 10.1016/j.jcv.2010.07.006
- Polyak SJ, Morishima C, Lohmann V, Pal S, Lee DY, et al. Identification of hepatoprotective flavonolignans from silymarin. Proc Natl Acad Sci U S A. 2010;107:5995. 10.1073/pnas.0914009107
- Seeff LB, Curto TM, Szabo G, Everson GT, Bonkovsky HL, et al. Herbal product use by persons enrolled in the hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial. Hepatology. 2008;47:605. PubMed
