Last update
5/17/2026
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Infographics
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.9
USERS' SCORE
Good
Based on 3 Reviews
8.4
Supplement Facts
Serving Size: 2 Softgels
Amount Per Serving
%DV
Calories
20
Total Fat
2 g
3%**
Saturated Fat
0.5 g
3%**
Polyunsaturated Fat
1 g
†
Monounsaturated Fat
0.5 g
†
Fish Oil Concentrate
2 g (2,000 mg)
†
Eicosapentaenoic Acid (EPA)
360 mg
†
Docosahexaenoic Acid (DHA)
240 mg
†
Top Medical Research Studies
9
We investigated the impact of diabetes on the levels of docosahexaenoic acid (DHA), an essential omega 3 fatty acid, in the retina of humans and mice. Our findings revealed that diabetic individuals had significantly lower DHA levels—40% less in peripheral regions and 25% less in the macula—compared to those without diabetes.
Additionally, we observed a reduction of retinal thickness and function in diabetic mice. Although there’s potential for dietary DHA to help with diabetic retinopathy, the current study suggests that diabetes is linked to reduced DHA and related retinal defects.
Additionally, we observed a reduction of retinal thickness and function in diabetic mice. Although there’s potential for dietary DHA to help with diabetic retinopathy, the current study suggests that diabetes is linked to reduced DHA and related retinal defects.
Read More
9
We examined the impact of omega-3 fatty acids from fish oil on diabetes in nonobese Goto-Kakizaki rats. Over eight weeks, these rats received fish oil supplements, while control groups were given plain water.
Our findings revealed that fish oil significantly enhanced glucose tolerance and insulin sensitivity in the diabetic rats. Additionally, it shifted T lymphocyte activity towards more immune-regulating patterns, reducing inflammation and promoting better overall metabolic health.
However, the study primarily involved animal models, so further research is needed to confirm these results in humans.
Our findings revealed that fish oil significantly enhanced glucose tolerance and insulin sensitivity in the diabetic rats. Additionally, it shifted T lymphocyte activity towards more immune-regulating patterns, reducing inflammation and promoting better overall metabolic health.
However, the study primarily involved animal models, so further research is needed to confirm these results in humans.
Read More
9
Omega-3 lowers type 2 diabetes odds
We conducted a study analyzing dietary omega-3 and omega-6 fatty acids and their connection to type 2 diabetes (T2DM) risk. Using data from 8,744 participants, we found that higher omega-3 intake was linked to a 58% lower chance of developing T2DM.
In contrast, a high omega-6 to omega-3 ratio appeared to increase the likelihood of T2DM. However, dietary omega-6 on its own didn’t show a significant effect in relation to diabetes risk. These findings suggest that enhancing omega-3 intake might be beneficial in managing T2DM risk.
In contrast, a high omega-6 to omega-3 ratio appeared to increase the likelihood of T2DM. However, dietary omega-6 on its own didn’t show a significant effect in relation to diabetes risk. These findings suggest that enhancing omega-3 intake might be beneficial in managing T2DM risk.
Read More
Most Useful Reviews
9
Eased painful periods
I've been taking Omega-3 regularly, and I’m very satisfied. It has alleviated my painful periods, and I manage my diabetes effectively with it. I trust it to fulfil its health benefits!
Read More
7.5
Family health support
Omega-3 aids in reducing diabetes risk, enhances blood circulation, and improves cognitive functions. My family and I take it twice a year, ensuring we maintain our health consistently. It's a worthwhile investment!
Read More
7.5
Blood sugar control
My blood sugar has been above standard recently, and I've discovered that Omega-3 can help lower it. Taking two Omega-3 capsules during meals aids in controlling blood sugar, which is essential for those with diabetes. It also alleviates inflammation post-exercise, making it beneficial for fitness enthusiasts.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.9
- All Researches
9
We investigated the impact of diabetes on the levels of docosahexaenoic acid (DHA), an essential omega 3 fatty acid, in the retina of humans and mice. Our findings revealed that diabetic individuals had significantly lower DHA levels—40% less in peripheral regions and 25% less in the macula—compared to those without diabetes.
Additionally, we observed a reduction of retinal thickness and function in diabetic mice. Although there’s potential for dietary DHA to help with diabetic retinopathy, the current study suggests that diabetes is linked to reduced DHA and related retinal defects.
Additionally, we observed a reduction of retinal thickness and function in diabetic mice. Although there’s potential for dietary DHA to help with diabetic retinopathy, the current study suggests that diabetes is linked to reduced DHA and related retinal defects.
Read More
9
We examined the impact of omega-3 fatty acids from fish oil on diabetes in nonobese Goto-Kakizaki rats. Over eight weeks, these rats received fish oil supplements, while control groups were given plain water.
Our findings revealed that fish oil significantly enhanced glucose tolerance and insulin sensitivity in the diabetic rats. Additionally, it shifted T lymphocyte activity towards more immune-regulating patterns, reducing inflammation and promoting better overall metabolic health.
However, the study primarily involved animal models, so further research is needed to confirm these results in humans.
Our findings revealed that fish oil significantly enhanced glucose tolerance and insulin sensitivity in the diabetic rats. Additionally, it shifted T lymphocyte activity towards more immune-regulating patterns, reducing inflammation and promoting better overall metabolic health.
However, the study primarily involved animal models, so further research is needed to confirm these results in humans.
Read More
9
Omega-3 lowers type 2 diabetes odds
We conducted a study analyzing dietary omega-3 and omega-6 fatty acids and their connection to type 2 diabetes (T2DM) risk. Using data from 8,744 participants, we found that higher omega-3 intake was linked to a 58% lower chance of developing T2DM.
In contrast, a high omega-6 to omega-3 ratio appeared to increase the likelihood of T2DM. However, dietary omega-6 on its own didn’t show a significant effect in relation to diabetes risk. These findings suggest that enhancing omega-3 intake might be beneficial in managing T2DM risk.
In contrast, a high omega-6 to omega-3 ratio appeared to increase the likelihood of T2DM. However, dietary omega-6 on its own didn’t show a significant effect in relation to diabetes risk. These findings suggest that enhancing omega-3 intake might be beneficial in managing T2DM risk.
Read More
9
We aimed to understand if docosahexaenoic acid (DHA) could protect diabetic mice from ischemic stroke. After administering DHA, we observed a significant reduction in brain injury and improved neurological function in these mice after stroke.
The treatment appeared to lower inflammation and cell death, as indicated by less neutrophils in the brain and changes in important proteins. Overall, DHA showed promise in managing stroke's damaging effects in diabetic models, suggesting potential benefits for clinical practice in diabetes care.
The treatment appeared to lower inflammation and cell death, as indicated by less neutrophils in the brain and changes in important proteins. Overall, DHA showed promise in managing stroke's damaging effects in diabetic models, suggesting potential benefits for clinical practice in diabetes care.
Read More
9
Omega-3 reduces inflammation, diabetes risk
We tested the effects of omega-3 fatty acids, specifically EPA and DHA, on diabetes risk factors linked to high levels of "bad" cholesterol. Over a 12-week period, individuals with elevated lipoprotein levels received daily omega-3 supplements.
We found that this intervention significantly reduced inflammation in fat tissue, improving factors like insulin function and fat metabolism. Overall, omega-3 supplementation showed promising results in lowering diabetes risk through its positive effects on inflammatory pathways.
However, while benefits were observed, the results indicated the need for further studies to fully understand the long-term impacts.
We found that this intervention significantly reduced inflammation in fat tissue, improving factors like insulin function and fat metabolism. Overall, omega-3 supplementation showed promising results in lowering diabetes risk through its positive effects on inflammatory pathways.
However, while benefits were observed, the results indicated the need for further studies to fully understand the long-term impacts.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Eased painful periods
I've been taking Omega-3 regularly, and I’m very satisfied. It has alleviated my painful periods, and I manage my diabetes effectively with it. I trust it to fulfil its health benefits!
Read More
7.5
Family health support
Omega-3 aids in reducing diabetes risk, enhances blood circulation, and improves cognitive functions. My family and I take it twice a year, ensuring we maintain our health consistently. It's a worthwhile investment!
Read More
7.5
Blood sugar control
My blood sugar has been above standard recently, and I've discovered that Omega-3 can help lower it. Taking two Omega-3 capsules during meals aids in controlling blood sugar, which is essential for those with diabetes. It also alleviates inflammation post-exercise, making it beneficial for fitness enthusiasts.
Read More
Frequently Asked Questions
7.5
Blood sugar control
My blood sugar has been above standard recently, and I've discovered that Omega-3 can help lower it. Taking two Omega-3 capsules during meals aids in controlling blood sugar, which is essential for those with diabetes. It also alleviates inflammation post-exercise, making it beneficial for fitness enthusiasts.
9
Eased painful periods
I've been taking Omega-3 regularly, and I’m very satisfied. It has alleviated my painful periods, and I manage my diabetes effectively with it. I trust it to fulfil its health benefits!
References
- Sugasini D, Yalagala PCR, Park JC, Ma G, Farooq Z, et al. Retinal Docosahexaenoic Acid Is Significantly Reduced in Diabetic Humans and Mice: Possible Relationship to Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2024;65:39. 10.1167/iovs.65.14.39
- Lobato TB, Santos ESS, Iser-Bem PN, Falcão HS, Gimenes GM, et al. Omega-3 Fatty Acids Weaken Lymphocyte Inflammatory Features and Improve Glycemic Control in Nonobese Diabetic Goto-Kakizaki Rats. Nutrients. 2024;16. 10.3390/nu16234106
- Coelho-Júnior HJ, Álvarez-Bustos A, Picca A, Calvani R, Rodriguez-Mañas L, et al. Dietary Intake of Polyunsaturated Fatty Acids Is Associated with Blood Glucose and Diabetes in Community-Dwelling Older Adults. Nutrients. 2024;16. 10.3390/nu16234087
- Durán AM, Zamora F, De León M. Dietary Docosahexaenoic Acid-Rich Supplementation Decreases Neurotoxic Lipid Mediators in Participants with Type 2 Diabetes and Neuropathic Pain. Nutrients. 2024;16. 10.3390/nu16234025
- Soria-Utrilla V, Sasso CV, Romero-Zerbo SY, Adarve-Castro A, López-Urdiales R, et al. Biomarkers of oxidation, inflammation and intestinal permeability in persons with diabetes mellitus with parenteral nutrition: A multicenter randomized trial. Clin Nutr. 2025;44:155. 10.1016/j.clnu.2024.11.044
- You Y, Sarkar S, Deiter C, Elliott EC, Nicora CD, et al. Reduction of Chemokine CXCL9 Expression by Omega-3 Fatty Acids via ADP-Ribosylhydrolase ARH3 in MIN6 Insulin-Producing Cells. Proteomics. 2025;25:e202400053. 10.1002/pmic.202400053
- Shakiba E, Pasdar Y, Asoudeh F, Najafi F, Saber A, et al. The relationship of dietary omega-3 fatty acid and omega-6 to omega-3 ratio intake and likelihood of type 2 diabetes in a cross-sectional study. BMC Endocr Disord. 2024;24:259. 10.1186/s12902-024-01787-y
- Liu C, Guo J, Guan L, Li C, Hu X, et al. Docosahexaenoic acid protects against ischemic stroke in diabetic mice by inhibiting inflammatory responses and apoptosis. Exp Neurol. 2025;385:115075. 10.1016/j.expneurol.2024.115075
- Bayat M, Koohpeyma F, Montazeri-Najafabady N, Dabbaghmanesh MH, Asmarian N, et al. The effects of modest intake of soy milk enriched with Lactobacillus casei and omega-3 on the testis parameters in diabetic rats: a stereological study. Int Urol Nephrol. 2025;57:1123. 10.1007/s11255-024-04243-x
- Xia J, Yin S, Yu J, Wang J, Jin X, et al. Improvement in Glycolipid Metabolism Parameters After Supplementing Fish Oil-Derived Omega-3 Fatty Acids Is Associated with Gut Microbiota and Lipid Metabolites in Type 2 Diabetes Mellitus. Nutrients. 2024;16. 10.3390/nu16213755
- Lamantia V, Bissonnette S, Beaudry M, Cyr Y, Rosiers CD, et al. EPA and DHA inhibit LDL-induced upregulation of human adipose tissue NLRP3 inflammasome/IL-1β pathway and its association with diabetes risk factors. Sci Rep. 2024;14:27146. 10.1038/s41598-024-73672-6
- Li J, Nan W, Huang X, Meng H, Wang S, et al. Eicosapentaenoic acid induces macrophage Mox polarization to prevent diabetic cardiomyopathy. EMBO Rep. 2024;25:5507. 10.1038/s44319-024-00271-x
- Schuchardt JP, Hahn A, Greupner T, Tintle NL, Westra J, et al. Higher docosahexaenoic acid proportions in blood are inversely associated with the prevalence of prediabetes: Evidence from the UK Biobank. Nutr Res. 2024;131:62. 10.1016/j.nutres.2024.09.009
- Rimmen EV, Mjøs SA, Søfteland E, Gudbrandsen OA. Intake of herring oil, but not of anchovy oil, resulted in a lower serum cholesterol concentration in male Zucker Diabetic Sprague Dawley rats. Br J Nutr. 2024;132:547. 10.1017/S0007114524001454
- Muzammil K, Khaleel AQ, Merza MS, Kyada A, Ariffin IA, et al. The effects of ω-3 fatty acids on inflammatory and oxidative stress markers in patients with Type 2 diabetes mellitus: A systematic review and meta-analysis of controlled trials. Prostaglandins Other Lipid Mediat. 2024;175:106887. 10.1016/j.prostaglandins.2024.106887
- Ao Y, Ye H, Liu X, Li Y, Liu H, et al. Fish oil supplementation in relation to the risk of chronic kidney disease among patients with diabetes. Diabetes Obes Metab. 2024;26:5283. 10.1111/dom.15880
