Last update
4/21/2026
Reviewed By
Infographics
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.9
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.9
Supplement Facts
Serving Size: 1 Fish Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Cholesterol
<5 mg
1%
Vitamin D3 (as Cholecalciferol) (from Lanolin)
25 mcg (1,000 IU)
125%
Fish Oil Concentrate
1.2 g (1,200 mg)
†
Omega-3 Fatty Acids:
Eicosapentaenoic Acid (EPA)
600 mg
†
Docosahexaenoic Acid (DHA)
300 mg
†
Top Medical Research Studies
9
We investigated the impact of diabetes on the levels of docosahexaenoic acid (DHA), an essential omega 3 fatty acid, in the retina of humans and mice. Our findings revealed that diabetic individuals had significantly lower DHA levels—40% less in peripheral regions and 25% less in the macula—compared to those without diabetes.
Additionally, we observed a reduction of retinal thickness and function in diabetic mice. Although there’s potential for dietary DHA to help with diabetic retinopathy, the current study suggests that diabetes is linked to reduced DHA and related retinal defects.
Additionally, we observed a reduction of retinal thickness and function in diabetic mice. Although there’s potential for dietary DHA to help with diabetic retinopathy, the current study suggests that diabetes is linked to reduced DHA and related retinal defects.
Read More
9
We examined the impact of omega-3 fatty acids from fish oil on diabetes in nonobese Goto-Kakizaki rats. Over eight weeks, these rats received fish oil supplements, while control groups were given plain water.
Our findings revealed that fish oil significantly enhanced glucose tolerance and insulin sensitivity in the diabetic rats. Additionally, it shifted T lymphocyte activity towards more immune-regulating patterns, reducing inflammation and promoting better overall metabolic health.
However, the study primarily involved animal models, so further research is needed to confirm these results in humans.
Our findings revealed that fish oil significantly enhanced glucose tolerance and insulin sensitivity in the diabetic rats. Additionally, it shifted T lymphocyte activity towards more immune-regulating patterns, reducing inflammation and promoting better overall metabolic health.
However, the study primarily involved animal models, so further research is needed to confirm these results in humans.
Read More
9
Omega-3 lowers type 2 diabetes odds
We conducted a study analyzing dietary omega-3 and omega-6 fatty acids and their connection to type 2 diabetes (T2DM) risk. Using data from 8,744 participants, we found that higher omega-3 intake was linked to a 58% lower chance of developing T2DM.
In contrast, a high omega-6 to omega-3 ratio appeared to increase the likelihood of T2DM. However, dietary omega-6 on its own didn’t show a significant effect in relation to diabetes risk. These findings suggest that enhancing omega-3 intake might be beneficial in managing T2DM risk.
In contrast, a high omega-6 to omega-3 ratio appeared to increase the likelihood of T2DM. However, dietary omega-6 on its own didn’t show a significant effect in relation to diabetes risk. These findings suggest that enhancing omega-3 intake might be beneficial in managing T2DM risk.
Read More
Most Useful Reviews
7.5
Healthy blood sugar
This supplement has successfully supported healthy blood sugar levels and lowered the risk of diabetes.
Read More
7.5
Prevent diabetes risk
Omega-3 acids regulate hormone production, facilitate oxygen transfer to tissues, support vascular health, and improve digestion. They normalise brain activity and help prevent diabetes and heart disease. Additionally, they assist in cleansing blood vessels from excess "bad" cholesterol, thus averting cholesterol plaque formation and enhancing vessel elasticity.
Read More
7.5
Beneficial for diabetes
Distinguished! After searching, I opted for this. Many recommended it for omega-3s. Occasionally, I feel nauseous, sometimes I don't. Taking it after a meal containing fat aids absorption. One pill daily is beneficial; it promotes heart health and diminishes the risks of cancer, high blood pressure, and diabetes.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.9
- All Researches
9
We investigated the impact of diabetes on the levels of docosahexaenoic acid (DHA), an essential omega 3 fatty acid, in the retina of humans and mice. Our findings revealed that diabetic individuals had significantly lower DHA levels—40% less in peripheral regions and 25% less in the macula—compared to those without diabetes.
Additionally, we observed a reduction of retinal thickness and function in diabetic mice. Although there’s potential for dietary DHA to help with diabetic retinopathy, the current study suggests that diabetes is linked to reduced DHA and related retinal defects.
Additionally, we observed a reduction of retinal thickness and function in diabetic mice. Although there’s potential for dietary DHA to help with diabetic retinopathy, the current study suggests that diabetes is linked to reduced DHA and related retinal defects.
Read More
9
We examined the impact of omega-3 fatty acids from fish oil on diabetes in nonobese Goto-Kakizaki rats. Over eight weeks, these rats received fish oil supplements, while control groups were given plain water.
Our findings revealed that fish oil significantly enhanced glucose tolerance and insulin sensitivity in the diabetic rats. Additionally, it shifted T lymphocyte activity towards more immune-regulating patterns, reducing inflammation and promoting better overall metabolic health.
However, the study primarily involved animal models, so further research is needed to confirm these results in humans.
Our findings revealed that fish oil significantly enhanced glucose tolerance and insulin sensitivity in the diabetic rats. Additionally, it shifted T lymphocyte activity towards more immune-regulating patterns, reducing inflammation and promoting better overall metabolic health.
However, the study primarily involved animal models, so further research is needed to confirm these results in humans.
Read More
9
Omega-3 lowers type 2 diabetes odds
We conducted a study analyzing dietary omega-3 and omega-6 fatty acids and their connection to type 2 diabetes (T2DM) risk. Using data from 8,744 participants, we found that higher omega-3 intake was linked to a 58% lower chance of developing T2DM.
In contrast, a high omega-6 to omega-3 ratio appeared to increase the likelihood of T2DM. However, dietary omega-6 on its own didn’t show a significant effect in relation to diabetes risk. These findings suggest that enhancing omega-3 intake might be beneficial in managing T2DM risk.
In contrast, a high omega-6 to omega-3 ratio appeared to increase the likelihood of T2DM. However, dietary omega-6 on its own didn’t show a significant effect in relation to diabetes risk. These findings suggest that enhancing omega-3 intake might be beneficial in managing T2DM risk.
Read More
9
We aimed to understand if docosahexaenoic acid (DHA) could protect diabetic mice from ischemic stroke. After administering DHA, we observed a significant reduction in brain injury and improved neurological function in these mice after stroke.
The treatment appeared to lower inflammation and cell death, as indicated by less neutrophils in the brain and changes in important proteins. Overall, DHA showed promise in managing stroke's damaging effects in diabetic models, suggesting potential benefits for clinical practice in diabetes care.
The treatment appeared to lower inflammation and cell death, as indicated by less neutrophils in the brain and changes in important proteins. Overall, DHA showed promise in managing stroke's damaging effects in diabetic models, suggesting potential benefits for clinical practice in diabetes care.
Read More
9
Omega-3 reduces inflammation, diabetes risk
We tested the effects of omega-3 fatty acids, specifically EPA and DHA, on diabetes risk factors linked to high levels of "bad" cholesterol. Over a 12-week period, individuals with elevated lipoprotein levels received daily omega-3 supplements.
We found that this intervention significantly reduced inflammation in fat tissue, improving factors like insulin function and fat metabolism. Overall, omega-3 supplementation showed promising results in lowering diabetes risk through its positive effects on inflammatory pathways.
However, while benefits were observed, the results indicated the need for further studies to fully understand the long-term impacts.
We found that this intervention significantly reduced inflammation in fat tissue, improving factors like insulin function and fat metabolism. Overall, omega-3 supplementation showed promising results in lowering diabetes risk through its positive effects on inflammatory pathways.
However, while benefits were observed, the results indicated the need for further studies to fully understand the long-term impacts.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Healthy blood sugar
This supplement has successfully supported healthy blood sugar levels and lowered the risk of diabetes.
Read More
7.5
Prevent diabetes risk
Omega-3 acids regulate hormone production, facilitate oxygen transfer to tissues, support vascular health, and improve digestion. They normalise brain activity and help prevent diabetes and heart disease. Additionally, they assist in cleansing blood vessels from excess "bad" cholesterol, thus averting cholesterol plaque formation and enhancing vessel elasticity.
Read More
7.5
Beneficial for diabetes
Distinguished! After searching, I opted for this. Many recommended it for omega-3s. Occasionally, I feel nauseous, sometimes I don't. Taking it after a meal containing fat aids absorption. One pill daily is beneficial; it promotes heart health and diminishes the risks of cancer, high blood pressure, and diabetes.
Read More
7.5
Prevents diabetes issues
Omegas (fatty acids) are crucial for maintaining beauty, youth, and health, as they reduce heart disease risks, enhance blood circulation, and improve mental performance, memory, and concentration. They also help lower blood pressure and prevent diabetes. Gelatin capsules are easy to swallow. I recommend it to everyone!
Read More
4
Reduced diabetes risk
Omega 3 supplements promote heart health by lowering bad cholesterol levels and reducing heart disease risk. They also possess anti-inflammatory properties that aid in reducing bodily inflammation. DHA is vital for brain health and believed to support brain function as one ages. Moreover, omega-3s reduce the likelihood of developing chronic diseases, including type 2 diabetes, while also aiding skin health and supporting growth and development in children and fetuses.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Sugasini D, Yalagala PCR, Park JC, Ma G, Farooq Z, et al. Retinal Docosahexaenoic Acid Is Significantly Reduced in Diabetic Humans and Mice: Possible Relationship to Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2024;65:39. 10.1167/iovs.65.14.39
- Lobato TB, Santos ESS, Iser-Bem PN, Falcão HS, Gimenes GM, et al. Omega-3 Fatty Acids Weaken Lymphocyte Inflammatory Features and Improve Glycemic Control in Nonobese Diabetic Goto-Kakizaki Rats. Nutrients. 2024;16. 10.3390/nu16234106
- Coelho-Júnior HJ, Álvarez-Bustos A, Picca A, Calvani R, Rodriguez-Mañas L, et al. Dietary Intake of Polyunsaturated Fatty Acids Is Associated with Blood Glucose and Diabetes in Community-Dwelling Older Adults. Nutrients. 2024;16. 10.3390/nu16234087
- Durán AM, Zamora F, De León M. Dietary Docosahexaenoic Acid-Rich Supplementation Decreases Neurotoxic Lipid Mediators in Participants with Type 2 Diabetes and Neuropathic Pain. Nutrients. 2024;16. 10.3390/nu16234025
- Soria-Utrilla V, Sasso CV, Romero-Zerbo SY, Adarve-Castro A, López-Urdiales R, et al. Biomarkers of oxidation, inflammation and intestinal permeability in persons with diabetes mellitus with parenteral nutrition: A multicenter randomized trial. Clin Nutr. 2025;44:155. 10.1016/j.clnu.2024.11.044
- You Y, Sarkar S, Deiter C, Elliott EC, Nicora CD, et al. Reduction of Chemokine CXCL9 Expression by Omega-3 Fatty Acids via ADP-Ribosylhydrolase ARH3 in MIN6 Insulin-Producing Cells. Proteomics. 2025;25:e202400053. 10.1002/pmic.202400053
- Shakiba E, Pasdar Y, Asoudeh F, Najafi F, Saber A, et al. The relationship of dietary omega-3 fatty acid and omega-6 to omega-3 ratio intake and likelihood of type 2 diabetes in a cross-sectional study. BMC Endocr Disord. 2024;24:259. 10.1186/s12902-024-01787-y
- Liu C, Guo J, Guan L, Li C, Hu X, et al. Docosahexaenoic acid protects against ischemic stroke in diabetic mice by inhibiting inflammatory responses and apoptosis. Exp Neurol. 2025;385:115075. 10.1016/j.expneurol.2024.115075
- Bayat M, Koohpeyma F, Montazeri-Najafabady N, Dabbaghmanesh MH, Asmarian N, et al. The effects of modest intake of soy milk enriched with Lactobacillus casei and omega-3 on the testis parameters in diabetic rats: a stereological study. Int Urol Nephrol. 2025;57:1123. 10.1007/s11255-024-04243-x
- Xia J, Yin S, Yu J, Wang J, Jin X, et al. Improvement in Glycolipid Metabolism Parameters After Supplementing Fish Oil-Derived Omega-3 Fatty Acids Is Associated with Gut Microbiota and Lipid Metabolites in Type 2 Diabetes Mellitus. Nutrients. 2024;16. 10.3390/nu16213755
- Lamantia V, Bissonnette S, Beaudry M, Cyr Y, Rosiers CD, et al. EPA and DHA inhibit LDL-induced upregulation of human adipose tissue NLRP3 inflammasome/IL-1β pathway and its association with diabetes risk factors. Sci Rep. 2024;14:27146. 10.1038/s41598-024-73672-6
- Li J, Nan W, Huang X, Meng H, Wang S, et al. Eicosapentaenoic acid induces macrophage Mox polarization to prevent diabetic cardiomyopathy. EMBO Rep. 2024;25:5507. 10.1038/s44319-024-00271-x
- Schuchardt JP, Hahn A, Greupner T, Tintle NL, Westra J, et al. Higher docosahexaenoic acid proportions in blood are inversely associated with the prevalence of prediabetes: Evidence from the UK Biobank. Nutr Res. 2024;131:62. 10.1016/j.nutres.2024.09.009
- Rimmen EV, Mjøs SA, Søfteland E, Gudbrandsen OA. Intake of herring oil, but not of anchovy oil, resulted in a lower serum cholesterol concentration in male Zucker Diabetic Sprague Dawley rats. Br J Nutr. 2024;132:547. 10.1017/S0007114524001454
- Muzammil K, Khaleel AQ, Merza MS, Kyada A, Ariffin IA, et al. The effects of ω-3 fatty acids on inflammatory and oxidative stress markers in patients with Type 2 diabetes mellitus: A systematic review and meta-analysis of controlled trials. Prostaglandins Other Lipid Mediat. 2024;175:106887. 10.1016/j.prostaglandins.2024.106887
- Ao Y, Ye H, Liu X, Li Y, Liu H, et al. Fish oil supplementation in relation to the risk of chronic kidney disease among patients with diabetes. Diabetes Obes Metab. 2024;26:5283. 10.1111/dom.15880
