Overview
Top Medical Research Studies
The results were impressive, showing that the nanogel not only improved drug retention in the skin but also noticeably reduced psoriasis symptoms in an animal model. While the treatment showed promise, our findings highlight its potential rather than guaranteeing complete efficacy.
Overall, this innovative approach may lead to more effective topical therapies for those struggling with psoriasis.
The results showed that the lecithin organogel significantly reduced psoriasis symptoms compared to both oral apremilast and standard topical treatments. This suggests that lecithin organogel could be an effective delivery method for treating psoriatic skin conditions.
The study found that this gel effectively penetrated deeper skin layers and led to a significant reduction in psoriasis symptoms, as measured by the PASI score.
Importantly, there were few side effects reported, making it a potentially safer option compared to traditional treatments. Overall, this hybrid nanostructured gel seems promising in treating psoriasis effectively.
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The results were impressive, showing that the nanogel not only improved drug retention in the skin but also noticeably reduced psoriasis symptoms in an animal model. While the treatment showed promise, our findings highlight its potential rather than guaranteeing complete efficacy.
Overall, this innovative approach may lead to more effective topical therapies for those struggling with psoriasis.
The results showed that the lecithin organogel significantly reduced psoriasis symptoms compared to both oral apremilast and standard topical treatments. This suggests that lecithin organogel could be an effective delivery method for treating psoriatic skin conditions.
In fact, we noted a significant increase in drug retention in the skin layers, which translated to better visual and histological improvements in psoriasis symptoms. Overall, the findings suggest that lecithin nanoparticles could offer a more effective way to manage psoriasis.
The study found that this gel effectively penetrated deeper skin layers and led to a significant reduction in psoriasis symptoms, as measured by the PASI score.
Importantly, there were few side effects reported, making it a potentially safer option compared to traditional treatments. Overall, this hybrid nanostructured gel seems promising in treating psoriasis effectively.
User Reviews
- All Reviews
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Frequently Asked Questions
Psoriasis is a chronic autoimmune condition that primarily affects the skin, leading to the rapid growth of skin cells that accumulate, forming scales and red patches that can be itchy and sometimes painful. These changes occur due to an abnormal immune response that accelerates the skin renewal process. The disease can vary in severity, with some individuals experiencing mild flare-ups while others endure more severe symptoms. Psoriasis commonly appears on the elbows, knees, scalp, and lower back, but it can occur anywhere on the body.
There are several types of psoriasis, with plaque psoriasis being the most common form, characterized by raised, inflamed patches covered with silvery-white scales. Other types include guttate, inverse, pustular, and erythrodermic psoriasis. While the exact cause of psoriasis is still not entirely understood, it is believed to involve genetic, environmental, and immune system factors. Treatments vary widely and can range from topical medications and phototherapy to systemic treatments aimed at reducing inflammation and slowing skin cell turnover. If you suspect you have psoriasis, consulting a healthcare provider is advisable to explore the most appropriate treatment options.
Lecithin is a natural substance that is found in various plant and animal tissues, primarily derived from soybeans, eggs, or sunflower seeds. It is a phospholipid, which means it contains both a hydrophilic (water-attracting) and hydrophobic (water-repellent) component. This unique structure makes lecithin an excellent emulsifier, which allows it to blend ingredients that typically don't mix well together, such as oil and water. As a result, it is commonly used in food products, cosmetics, and nutritional supplements to improve texture, stability, and shelf life.
In food products, lecithin can be found in a wide range of items, from chocolates to baked goods, providing a smoother mouthfeel and enhancing flavor distribution. Additionally, lecithin plays a role in promoting better absorption of certain nutrients in the body, which has led to its popularity as a dietary supplement. While lecithin is generally considered safe for consumption, those with soy allergies should opt for alternatives like sunflower lecithin. Whether you're a home cook looking to improve your dishes or someone interested in the potential health benefits, understanding lecithin's versatile uses can enhance your culinary and nutritional knowledge.
Lecithin, a fatty substance found in various foods and can also be taken as a supplement, has been studied for its potential health benefits, including its role in skin health. Some proponents suggest that lecithin may help with psoriasis due to its properties as an emulsifier and its ability to support healthy skin barrier function. However, there is currently limited scientific research directly linking lecithin supplementation to significant improvements in psoriasis symptoms. While some individuals may report anecdotal benefits, it is essential to approach lecithin as a complementary option rather than a standalone treatment for psoriasis.
If you are considering lecithin for psoriasis management, it's advisable to consult a healthcare professional first. They can offer personalized guidance based on your specific condition and help you explore effective, evidence-based treatments. Remember, managing psoriasis often requires a multifaceted approach that typically includes prescribed medications, lifestyle modifications, and sometimes dietary adjustments. Always prioritize treatments that are supported by clinical evidence to ensure the best outcomes for your skin health.
Based on user reviews, individuals taking sunflower lecithin for psoriasis generally report seeing varying degrees of improvement in their condition within a time frame of two weeks to two months. For instance, one user noted a significant boost after just two weeks of use, stating it was "a definite must-try" for psoriasis management (Read Review). Another user experienced marked improvements after two months, with most psoriasis spots vanishing (Read Review).
Additionally, several users mentioned continuous or cyclical use of the supplement, allowing them to maintain or achieve remission from psoriasis over time (Read Review). It's important to note that each individual's response might vary, and while some see quick improvements, others may experience more gradual effects. Thus, for optimal results, consistency and patience in use are key.
This supplement shows promise for treating psoriasis, backed by various scientific studies that suggest its effectiveness. One study explored curcumin combined with lecithin, revealing that patients receiving this treatment alongside standard steroid therapy experienced significant improvements in psoriasis severity and reduced inflammatory markers after 12 weeks [7]. Furthermore, a clinical trial on antioxidant supplements, including coenzyme Q10, vitamin E, and selenium, indicated noticeable clinical improvements in severe psoriasis patients compared to a placebo group [8].
Other innovative treatments, such as couple of gels formulated with lecithin and adjunct compounds, have demonstrated similarly encouraging results. For instance, lecithin-chitosan hybrid nanoparticles facilitated enhanced drug delivery for tacrolimus, leading to greater retention in skin layers and improved visual outcomes in psoriasis [5]. The incorporation of gold nanoparticles with lecithin also showed significant anti-psoriatic effects, indicating a potential pathway to enhance treatment efficacy [4]. These cumulative findings highlight that certain supplements and formulations are gaining traction in the research community for supporting the management of psoriasis.
Based on user reviews, many individuals have reported significant improvements in their psoriasis symptoms after taking sunflower lecithin. For instance, one user noted a remarkable reduction in psoriasis spots after just two months of continuous use, stating that almost all their spots vanished (Read Review). Others reported entering remission from their psoriasis, as well as positive changes in associated conditions such as nail psoriasis (Read Review).
Several users have highlighted the importance of consistent intake for maintaining or achieving improvement, with reports ranging from noticeable changes within as little as two weeks (Read Review) to significant effects lasting beyond a month after stopping the supplement (Read Review). However, while many have experienced beneficial outcomes, it's important to note that individual results can vary; some users experienced worsening symptoms or found the large capsule size inconvenient (Read Review). Overall, users appreciate how sunflower lecithin complements other treatment methods, contributing to improved skin health and overall well-being.
Based on user reviews, many individuals reported positive experiences when combining sunflower lecithin with other supplements for managing psoriasis. One user shared that the supplement, when used alongside omega and vitamin D, had "amazing" effects, leading to clear skin with no traces of psoriasis even after a month of stopping the first course (Read Review). Another user noted that they incorporated sunflower lecithin as a supportive measure after more potent liver medications, suggesting that it complements existing treatments effectively (Read Review).
Additionally, several users mentioned their nutritionist's recommendations for continuous use of sunflower lecithin in their psoriasis therapy, indicating its perceived value in conjunction with other treatments (Read Review). Overall, it appears that combining sunflower lecithin with other nutrients or therapies may enhance the overall effects on skin health, with users expressing satisfaction regarding their improvements when taking a more holistic approach to their psoriasis management.
Users report varying dosages for lecithin in treating psoriasis, with some taking one capsule per meal as a starting point. For instance, one user has observed significant improvements after consistently taking one capsule with each meal over two months, noting that almost all psoriasis spots vanished during that time (Read Review). Another user mentioned taking lecithin in cycles, suggesting flexibility in dosage depending on personal health needs and specific treatment goals (Read Review).
Several reviews emphasize the importance of consistency in taking lecithin, with improvements often noticed within a few weeks to a couple of months. One account highlights that after three weeks of use, noticeable fading of psoriatic plaques occurred, offering evidence that a longer-term commitment may yield better results (Read Review). Another user has been taking the supplement for seven years, indicating a long-term preventative strategy alongside addressing flare-ups (Read Review). Overall, while there are suggestions of specific dosages, user experiences suggest tailoring the intake of lecithin capsules to individual lifestyles and health situations.
After 12 weeks, we found that those who took curcumin experienced greater improvement in their psoriasis severity scores. Additionally, their serum levels of the inflammatory marker IL-22 were significantly reduced. Thus, curcumin can be an effective complement to traditional treatments for psoriasis.
Our findings indicated that those who received the antioxidants showed noticeable clinical improvement compared to the placebo group. This suggests that incorporating these antioxidants in treatment could support psoriasis management effectively.
In fact, we noted a significant increase in drug retention in the skin layers, which translated to better visual and histological improvements in psoriasis symptoms. Overall, the findings suggest that lecithin nanoparticles could offer a more effective way to manage psoriasis.
References
- Mujtaba MA, Gangane P, Ali A, Chaudhari S, Kaleem M, et al. Karanjin-loaded soya lecithin-based ethosomal nanogel for the therapeutic intervention of psoriasis: formulation development, factorial design based-optimization,andassessment. Biomed Mater. 2024;19. doi:10.1088/1748-605X/ad5e51
- Bule P, Kadkanje P, Kshirsagar R, Puppala ER, Naidu VGM, et al. Formulation characterization of lecithin organogel as topical drug delivery system for psoriasis: In-vitro permeation and preclinical evaluation. Drug Dev Res. 2024;85:e22191. doi:10.1002/ddr.22191
- Hazari SA, Sheikh A, Abourehab MAS, Tulbah AS, Kesharwani P. Self-assembled Gallic acid loaded lecithin-chitosan hybrid nanostructured gel as a potential tool against imiquimod-induced psoriasis. Environ Res. 2023;234:116562. doi:10.1016/j.envres.2023.116562
- Fereig S, El-Zaafarany GM, Arafa MG, Abdel-Mottaleb MMA. Boosting the anti-inflammatory effect of self-assembled hybrid lecithin-chitosan nanoparticles via hybridization with gold nanoparticles for the treatment of psoriasis: elemental mapping and modeling. Drug Deliv. 2022;29:1726. doi:10.1080/10717544.2022.2081383
- Fereig SA, El-Zaafarany GM, Arafa MG, Abdel-Mottaleb MMA. Self-assembled tacrolimus-loaded lecithin-chitosan hybrid nanoparticles for in vivo management of psoriasis. Int J Pharm. 2021;608:121114. doi:10.1016/j.ijpharm.2021.121114
- Doppalapudi S, Jain A, Chopra DK, Khan W. Psoralen loaded liposomal nanocarriers for improved skin penetration and efficacy of topical PUVA in psoriasis. Eur J Pharm Sci. 2017;96:515. doi:10.1016/j.ejps.2016.10.025
- Antiga E, Bonciolini V, Volpi W, Del Bianco E, Caproni M. Oral Curcumin (Meriva) Is Effective as an Adjuvant Treatment and Is Able to Reduce IL-22 Serum Levels in Patients with Psoriasis Vulgaris. Biomed Res Int. 2015;2015:283634. doi:10.1155/2015/283634
- Kharaeva Z, Gostova E, De Luca C, Raskovic D, Korkina L. Clinical and biochemical effects of coenzyme Q(10), vitamin E, and selenium supplementation to psoriasis patients. Nutrition. 2009;25:295. doi:10.1016/j.nut.2008.08.015
