' 
SCIENTIFIC SCORE
Possibly Effective
Based on 27 Researches
7.6
USERS' SCORE
Good
Based on 10 Reviews
8.6
Supplement Facts
Serving Size: 1 Gummy
Amount Per Serving
%DV
Calories
5
Total Carbohydrate
2 g
1%**
Dietary Fiber
<1 g
2%**
Total Sugars
1 g
***
Includes 1 g Added Sugars
2%**
Sodium
5 mg
0%
Probiotic Blend1 Billion CFU
10 mg
***
Bacillus coagulans SNZ 1969,Bacillus subtilis DE111®
Top Medical Research Studies
9.5
Bacillus coagulans improves constipation
Bacillus coagulans Unique IS2 in Constipation: A Double-Blind, Placebo-Controlled Study.
Strong relevance to constipation treatment
We evaluated how Bacillus coagulans Unique IS2 impacts functional constipation by conducting a double-blind, placebo-controlled study with 100 adults. Participants received either the probiotic or a placebo daily for four weeks.
By the end of the study, those taking the probiotic reported a significant increase in bowel movements and improved stool consistency. In fact, 98% of probiotic users achieved normal stool consistency, compared to just 74% in the placebo group.
Moreover, the probiotic group experienced relief from associated symptoms like painful defecation and abdominal pain. This shows Bacillus coagulans Unique IS2 is effective in treating constipation.
By the end of the study, those taking the probiotic reported a significant increase in bowel movements and improved stool consistency. In fact, 98% of probiotic users achieved normal stool consistency, compared to just 74% in the placebo group.
Moreover, the probiotic group experienced relief from associated symptoms like painful defecation and abdominal pain. This shows Bacillus coagulans Unique IS2 is effective in treating constipation.
Read More
9
Bacillus coagulans improves constipation
Spore-forming Bacillus coagulans SNZ 1969 improved intestinal motility and constipation perception mediated by microbial alterations in healthy adults with mild intermittent constipation: A randomized controlled trial.
High relevance for gut health research
We explored the effects of Bacillus coagulans SNZ 1969 on mild intermittent constipation in healthy adults over an 8-week period. In this randomized controlled trial, participants received either the supplement or a placebo.
Results showed significant improvements in colonic transit time, increases in weekly bowel movements, and decreased bowel discomfort. Additionally, changes in gut microbiota composition were linked to these improvements.
Overall, our findings indicate that Bacillus coagulans can effectively enhance gut motility and relieve constipation symptoms in individuals with lower fruit and vegetable intake.
Results showed significant improvements in colonic transit time, increases in weekly bowel movements, and decreased bowel discomfort. Additionally, changes in gut microbiota composition were linked to these improvements.
Overall, our findings indicate that Bacillus coagulans can effectively enhance gut motility and relieve constipation symptoms in individuals with lower fruit and vegetable intake.
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9
Bacterial treatment improves gut motility
Tryptophan-synthesizing bacteria enhance colonic motility.
High relevance to GI motility
We investigated how Bacillus subtilis can help with constipation by treating mice with this specific bacteria. Over one week, the mice that received B. subtilis showed improved colonic motility and higher levels of tryptophan, a precursor for serotonin, compared to those that did not receive the treatment.
Notably, these effects were linked to enhanced serotonin signaling, as blocking serotonin receptors hindered this benefit. However, heat-inactivated bacteria or a different strain lacking tryptophan synthesis did not produce similar outcomes, indicating that live, active bacteria are crucial for this effect.
Notably, these effects were linked to enhanced serotonin signaling, as blocking serotonin receptors hindered this benefit. However, heat-inactivated bacteria or a different strain lacking tryptophan synthesis did not produce similar outcomes, indicating that live, active bacteria are crucial for this effect.
Read More
Most Useful Reviews
9.5
Successful daily use
We love these! After months of searching for a remedy for my daughter's potty issues, we are thrilled to have found these. Frequent constipation in a four-year-old is dreadful. She takes them daily and has regular bowel movements without problems. We also noticed that her eczema has tremendously improved. I couldn't recommend these enough; they are wonderful.
Read More
10
Transformed bowel experience
My daughter suffered from severe constipation, which was worsened by her reluctance to eat. This probiotic made a monumental difference in our lives; previously, she would call to go potty every 20 minutes without success. Now, she goes independently during the day, and her trips to the toilet are quick and painless, improving our quality of life significantly.
Read More
9.5
Remedied severe constipation
My daughter suffered from severe constipation, making it difficult to encourage healthy eating habits. We tried these probiotic vitamins, which have been a godsend. She takes just one a day, and now she spends only 2 to 3 minutes on the toilet, compared to the previous struggle that lasted much longer. These vitamins have transformed her experience with probiotics positively.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 27 Researches
7.6
- All Researches
9.5
Bacillus coagulans improves constipation
Bacillus coagulans Unique IS2 in Constipation: A Double-Blind, Placebo-Controlled Study.
Strong relevance to constipation treatment
We evaluated how Bacillus coagulans Unique IS2 impacts functional constipation by conducting a double-blind, placebo-controlled study with 100 adults. Participants received either the probiotic or a placebo daily for four weeks.
By the end of the study, those taking the probiotic reported a significant increase in bowel movements and improved stool consistency. In fact, 98% of probiotic users achieved normal stool consistency, compared to just 74% in the placebo group.
Moreover, the probiotic group experienced relief from associated symptoms like painful defecation and abdominal pain. This shows Bacillus coagulans Unique IS2 is effective in treating constipation.
By the end of the study, those taking the probiotic reported a significant increase in bowel movements and improved stool consistency. In fact, 98% of probiotic users achieved normal stool consistency, compared to just 74% in the placebo group.
Moreover, the probiotic group experienced relief from associated symptoms like painful defecation and abdominal pain. This shows Bacillus coagulans Unique IS2 is effective in treating constipation.
Read More
9
Probiotic blend aids constipation relief
Blending Three Probiotics Alleviates Loperamide-Induced Constipation in Sprague-Dawley (SD)-Rats.
Score indicates high relevance
We investigated the effects of BIOVITA 3, a blend of three probiotic bacteria, on constipation in Sprague-Dawley rats. Using loperamide to induce constipation, we observed that those given BIOVITA 3 showed significant improvements in fecal volume, moisture, and gastrointestinal transit time. Additionally, we noted positive changes in gut health markers, including short chain fatty acids and microbial diversity. This promising research indicates that BIOVITA 3 could be a beneficial ingredient in foods aimed at relieving constipation.
Read More
9
Bacterial treatment improves gut motility
Tryptophan-synthesizing bacteria enhance colonic motility.
High relevance to GI motility
We investigated how Bacillus subtilis can help with constipation by treating mice with this specific bacteria. Over one week, the mice that received B. subtilis showed improved colonic motility and higher levels of tryptophan, a precursor for serotonin, compared to those that did not receive the treatment.
Notably, these effects were linked to enhanced serotonin signaling, as blocking serotonin receptors hindered this benefit. However, heat-inactivated bacteria or a different strain lacking tryptophan synthesis did not produce similar outcomes, indicating that live, active bacteria are crucial for this effect.
Notably, these effects were linked to enhanced serotonin signaling, as blocking serotonin receptors hindered this benefit. However, heat-inactivated bacteria or a different strain lacking tryptophan synthesis did not produce similar outcomes, indicating that live, active bacteria are crucial for this effect.
Read More
9
Bacillus subtilis aids constipation treatment
Bacillus Subtilis Promotes the Release of 5-HT to Regulate Intestinal Peristalsis in STC Mice via Bile Acid and Its Receptor TGR5 Pathway.
Highly relevant findings on STC
We sought to understand how Bacillus subtilis affects slow transit constipation (STC) and its underlying mechanics. Using a mouse model, we treated STC with Bacillus subtilis and observed notable improvements.
Our findings showed that Bacillus subtilis significantly increased defecation rates and improved colon health. It also stimulated the release of serotonin from intestinal cells via the bile acid TGR5 receptor pathway, enhancing intestinal activity. Overall, this treatment appears beneficial for managing STC.
Our findings showed that Bacillus subtilis significantly increased defecation rates and improved colon health. It also stimulated the release of serotonin from intestinal cells via the bile acid TGR5 receptor pathway, enhancing intestinal activity. Overall, this treatment appears beneficial for managing STC.
Read More
9
BC01 probiotic alleviates constipation
Efficacy of BC01 on loperamide hydrochloride-induced constipation model in Kunming mice.
High relevance due to significant findings
We investigated how the probiotic Bacillus Coagulans (BC01) affects constipation in a mouse model. Mice were divided into groups receiving either saline, the constipation-inducing agent loperamide, a control laxative, or BC01 at low and high doses.
After treatment, BC01 significantly improved intestinal movement and increased fecal water content, helping relieve constipation symptoms. It also positively influenced gut motility and overall health by restoring intestinal microbiota balance and regulating related gene expression.
Notably, the high-dose BC01 treatment showed the greatest effectiveness.
After treatment, BC01 significantly improved intestinal movement and increased fecal water content, helping relieve constipation symptoms. It also positively influenced gut motility and overall health by restoring intestinal microbiota balance and regulating related gene expression.
Notably, the high-dose BC01 treatment showed the greatest effectiveness.
Read More
User Reviews
USERS' SCORE
Good
Based on 10 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Successful daily use
We love these! After months of searching for a remedy for my daughter's potty issues, we are thrilled to have found these. Frequent constipation in a four-year-old is dreadful. She takes them daily and has regular bowel movements without problems. We also noticed that her eczema has tremendously improved. I couldn't recommend these enough; they are wonderful.
Read More
10
Transformed bowel experience
My daughter suffered from severe constipation, which was worsened by her reluctance to eat. This probiotic made a monumental difference in our lives; previously, she would call to go potty every 20 minutes without success. Now, she goes independently during the day, and her trips to the toilet are quick and painless, improving our quality of life significantly.
Read More
9.5
Remedied severe constipation
My daughter suffered from severe constipation, making it difficult to encourage healthy eating habits. We tried these probiotic vitamins, which have been a godsend. She takes just one a day, and now she spends only 2 to 3 minutes on the toilet, compared to the previous struggle that lasted much longer. These vitamins have transformed her experience with probiotics positively.
Read More
9.5
Consistent health improvement
I don't know if it's genetics or this probiotic, but since our 4-year-old started taking it, she hasn’t fallen ill. It has also resolved her constipation issues, similar to our neighbour's son. We use Amazon's autoship feature, ensuring we never run out, and it's more economical than drugstore prices. She enjoys the taste, making it an easy addition to her routine.
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8.8
Eased constipation issues
My daughter, who has chronic constipation due to a genetic condition, has benefited immensely from this probiotic. She takes miralax daily but was still struggling with hard stool. Since starting this product, her bowel movements have improved from once a week to every other day and then to daily. She doesn't mind the taste or texture, and I hope it continues to work as it has already brought us remarkable results.
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