'
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.4
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size: 3 Tablets
Amount Per Serving
%DV
Vitamin B6 (as pyridoxine HCl)
25 mg
1,471%
Magnesium (as magnesium oxide)
400 mg
95%

Top Medical Research Studies

8
Magnesium alleviates menstrual bloating
Magnesium supplementation alleviates premenstrual symptoms of fluid retention.
Study highly relevant to topic
We explored the impact of magnesium supplementation on bloating as part of a larger study examining premenstrual symptoms. In our randomized, double-blind, placebo-controlled design, we administered a daily dose of 200 mg of magnesium (as MgO) to participants over the course of two menstrual cycles. Each volunteer kept track of their symptoms using a detailed diary with twenty-two items.

Initially, we found no difference in premenstrual symptoms between the magnesium and placebo groups during the first month. However, during the second month, participants taking magnesium experienced a notable decrease in bloating and hydration-related symptoms such as weight gain and breast tenderness. This reduction in symptoms was statistically significant, indicating that magnesium can indeed alleviate certain premenstrual symptoms like bloating.

Our findings suggest that magnesium supplementation, particularly in the context of fluid retention and bloating, could be beneficial for women experiencing these discomforts during their menstrual cycle. Overall, this study opens the door to considering magnesium as an effective remedy for mild premenstrual bloating.
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9.5
Magnesium treatment in goats
Grayanotoxin poisoning in three goats.
Moderate relevance; mixed findings
In our analysis of a recent case involving Nubian goats, we observed that three out of six goats experienced severe symptoms after consuming an azalea branch. They presented with bloating, regurgitation, and neurological signs, prompting their urgent referral to the zoo's veterinary hospital.

While the goats received a combination of treatments including magnesium hydroxide, activated charcoal, and lactated Ringer's solution, they intriguingly recovered within 24 hours. This raises questions about the specific role magnesium played in alleviating their bloating symptoms since it was administered alongside other treatments.

Although magnesium has been recognized for its potential benefits in various medical scenarios, the study does not provide enough isolation of its effects on bloating alone. Given that the recovery was quick, we can only partially attribute the improvement to magnesium without further research to clarify its direct impact.

Therefore, while magnesium's use is noteworthy, we should remain cautious about drawing strong conclusions regarding its effectiveness specifically for bloating in this context.
Read More
8
Vitamin B6 improves IBS symptoms
Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients.
Relevant but not isolated effect.
We conducted a controlled trial involving twenty-five patients diagnosed with Irritable Bowel Syndrome (IBS) to explore the effects of a unique combination of probiotics—Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001—along with vitamin B6 on gastrointestinal symptoms, particularly bloating.

Over a period of two months, we randomly assigned patients to receive either the probiotic combination with vitamin B6 or a placebo, ensuring that the study design was double-blind to eliminate bias. Throughout the study, we assessed symptoms, including abdominal pain and bloating, as well as the overall severity of IBS.

Remarkably, our findings revealed that the probiotic formulation significantly reduced bloating, showing a decrease of 36.35% compared to a slight increase with the placebo. This improvement also corresponded with reduced abdominal pain and improved intestinal health indicators. The probiotics not only alleviated bloating but also favored a healthier balance of gut bacteria, suggesting a positive overall impact on the IBS patients’ digestive wellness.

Although we cannot attribute effects solely to vitamin B6 since it was used in combination with probiotics, the results indicate that this formulation can improve symptoms associated with bloating and overall IBS severity. Thus, our study illuminates a potential approach for better managing IBS symptoms without relying solely on traditional medications.
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Most Useful Reviews

8.8
No side effects
No Gastrointestinal Side Effects. With this Magnesium Oxide supplement from Solgar, you gain the benefits of Magnesium without the side effects like bloating and gas that other brands cause. I've experienced none at all with Solgar. Instead, I've had less muscle and nerve pain and improved sleep.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.4
9.5
Magnesium treatment in goats
Grayanotoxin poisoning in three goats.
Moderate relevance; mixed findings
In our analysis of a recent case involving Nubian goats, we observed that three out of six goats experienced severe symptoms after consuming an azalea branch. They presented with bloating, regurgitation, and neurological signs, prompting their urgent referral to the zoo's veterinary hospital.

While the goats received a combination of treatments including magnesium hydroxide, activated charcoal, and lactated Ringer's solution, they intriguingly recovered within 24 hours. This raises questions about the specific role magnesium played in alleviating their bloating symptoms since it was administered alongside other treatments.

Although magnesium has been recognized for its potential benefits in various medical scenarios, the study does not provide enough isolation of its effects on bloating alone. Given that the recovery was quick, we can only partially attribute the improvement to magnesium without further research to clarify its direct impact.

Therefore, while magnesium's use is noteworthy, we should remain cautious about drawing strong conclusions regarding its effectiveness specifically for bloating in this context.
Read More
9
Buckwheat shows promise for NCGS
Symptomatic efficacy of buckwheat products in Non-Celiac Gluten Sensitivity (NCGS).
Positive findings on symptom relief
We conducted a study to explore the effects of dietary magnesium on bloating, particularly focusing on patients with Non-Celiac Gluten Sensitivity (NCGS). In a well-structured, randomized crossover trial involving 19 participants, we provided patients with products made from buckwheat while they also maintained their regular gluten-free diet in separate phases.

Our findings showed that when patients consumed buckwheat products, they reported a significant decrease in abdominal discomfort and bloating. Notably, there was a quantified increase in serum magnesium levels, suggesting that magnesium may play a role in alleviating some gastrointestinal symptoms.

However, we also observed that the control group showed a worsening of various NCGS symptoms such as nausea and headaches during the regular diet phase. While magnesium levels increased with the buckwheat diet, we can’t definitively single out magnesium as the sole beneficial factor regarding bloating. Nonetheless, this study points towards a promising role for buckwheat and its nutritional components in improving symptoms for those suffering from NCGS.
Read More
8
Vitamin B6 improves IBS symptoms
Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients.
Relevant but not isolated effect.
We conducted a controlled trial involving twenty-five patients diagnosed with Irritable Bowel Syndrome (IBS) to explore the effects of a unique combination of probiotics—Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001—along with vitamin B6 on gastrointestinal symptoms, particularly bloating.

Over a period of two months, we randomly assigned patients to receive either the probiotic combination with vitamin B6 or a placebo, ensuring that the study design was double-blind to eliminate bias. Throughout the study, we assessed symptoms, including abdominal pain and bloating, as well as the overall severity of IBS.

Remarkably, our findings revealed that the probiotic formulation significantly reduced bloating, showing a decrease of 36.35% compared to a slight increase with the placebo. This improvement also corresponded with reduced abdominal pain and improved intestinal health indicators. The probiotics not only alleviated bloating but also favored a healthier balance of gut bacteria, suggesting a positive overall impact on the IBS patients’ digestive wellness.

Although we cannot attribute effects solely to vitamin B6 since it was used in combination with probiotics, the results indicate that this formulation can improve symptoms associated with bloating and overall IBS severity. Thus, our study illuminates a potential approach for better managing IBS symptoms without relying solely on traditional medications.
Read More
8
Vitamin B6 alleviates bloating symptoms
Effects of and on Gut Microbiota in Patients with Lactose Intolerance and Persisting Functional Gastrointestinal Symptoms: A Randomised, Double-Blind, Cross-Over Study.
Study shows significant bloating reduction
We conducted a randomized, double-blind, cross-over study to evaluate how vitamin B6, alongside probiotics, affects bloating in lactose intolerant individuals experiencing ongoing gastrointestinal symptoms despite following a lactose-free diet.

In our study involving 23 participants, we compared a combination treatment of probiotics and vitamin B6 to a placebo. The results were promising: participants who received the probiotic and vitamin B6 treatment reported a significant decrease in bloating. We saw a p-value of 0.028, which suggests that the treatment had a notable effect.

Additionally, we noticed changes in gut microbiota, with the supplementation encouraging the growth of beneficial bacteria, such as Bifidobacterium, which plays a key role in lactose digestion. This means not only did vitamin B6 appear to ease bloating, but it also helped improve the overall gut environment for those struggling with lactose intolerance.

Overall, our findings indicate that combining probiotics with vitamin B6 could provide relief for lactose intolerant patients dealing with persistent digestive issues, particularly bloating. This is good news for individuals looking for ways to enhance their gut health and manage their symptoms more effectively.
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8
Magnesium's effects on bloating unclear
Successful treatment of idiopathic tetanus using metronidazole, magnesium, and acepromazine in Hanwoo (Korean indigenous cattle) yearling bull.
Focus on magnesium treatment relevance
We explored the effectiveness of magnesium treatment in a 9-month-old Hanwoo bull diagnosed with severe tetanus—a condition characterized by intense muscle spasms and tension. During this case study, we noted the use of several treatments, including metronidazole, magnesium, and acepromazine, to manage the symptoms.

Magnesium was administered for 7 days alongside sedatives to alleviate muscle spasticity and spasms. While the bull experienced severe bloat that necessitated a temporary rumenostomy, the specific impact of magnesium on bloating is challenging to isolate due to the combined treatment approach.

As we monitored the bull’s progress, we saw marked improvements in muscle tension, culminating in the bull standing up after being in a lateral recumbent position. By day 17 post-onset, all symptoms related to tetanus had resolved, allowing for a return to a normal diet. Although magnesium was part of the treatment regimen, its singular effect on bloating remains inconclusive in this case.
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User Reviews

USERS' SCORE
Good
Based on 1 Review
8.5
8.8
No side effects
No Gastrointestinal Side Effects. With this Magnesium Oxide supplement from Solgar, you gain the benefits of Magnesium without the side effects like bloating and gas that other brands cause. I've experienced none at all with Solgar. Instead, I've had less muscle and nerve pain and improved sleep.
Read More
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