Overview

SCIENTIFIC SCORE
Questionable
Based on 7 Researches
6.6
USERS' SCORE
Moderately Good
Based on 16 Reviews
7.6
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Zinc(from 270 mg Zinc Picolinate)
50 mg
455% 

Top Medical Research Studies

9
Zinc deficiency linked to anemia
We explored the connection between zinc deficiency and anemia through the case of an 18-year-old woman who faced a series of health issues, including urinary tract infections and insulin dysfunction. After a thorough assessment, she was diagnosed with zinc deficiency, shedding light on how this overlooked issue can impact overall health.

What stood out to us was the rapid recovery the patient experienced after beginning oral zinc supplementation. Zinc plays a critical role in numerous bodily functions, including immune support and protein regulation. By addressing her deficiency, we observed significant improvement in her symptoms, including anemia.

The patient’s diet contained high levels of substances that were inhibiting her zinc absorption, which likely contributed to her condition. This case emphasizes the importance of recognizing zinc deficiency as a potential underlying cause for unexplained health issues, particularly anemia. Prompt diagnosis and treatment can lead to a complete turnaround in the patient's health.

By sharing this experience, we hope to raise awareness among clinicians about the vital role of zinc in managing anemia and encourage timely interventions for patients showing diverse symptoms.
Read More
We observed an intriguing case involving a 51-year-old woman diagnosed with treatment-resistant schizophrenia (TRS) who developed severe anemia while undergoing clozapine therapy. This case highlights the complex relationship between clozapine, a potent antipsychotic, and zinc deficiency. Through identifying zinc deficiency as a possible contributing factor to the anemia, we explored how zinc supplementation could play a pivotal role in restoring hemoglobin levels.

Following zinc supplementation, we noted impressive improvements in her hemoglobin, allowing the patient to continue her clozapine at a therapeutic dosage. Remarkably, she has shown stability since, with no signs of recurrent anemia. While clozapine can lead to various complications, including anemia, this case suggests that addressing zinc levels may be critical for patients receiving this treatment.

However, we must acknowledge that the exact mechanism linking zinc deficiency and clozapine-related anemia remains unclear. Thus, further investigation is warranted to fully understand this relationship and the potential of zinc in managing anemia, particularly in patients on clozapine.
Read More
We explored the impact of zinc treatment on anemia, particularly focusing on preterm and low birth weight infants in low- and middle-income countries. Previous evidence suggested a strong correlation between zinc supplementation and the reduction of anemia rates.

Our review revealed that adding zinc, along with other micronutrients, seems to show promising benefits. Specifically, it can help reduce levels of anemia in vulnerable populations, contributing to better health outcomes.

What's important to note is that benefits from zinc supplementation were often accompanied by other nutrients, making it challenging to isolate its specific effectiveness. Nevertheless, the consensus indicates that zinc, along with iron and vitamin A, plays a supportive role in promoting overall growth and reducing complications related to anemia.

Therefore, while we didn't claim that zinc alone is a catch-all solution, it does hold significant promise when combined with a broader nutritional strategy. This highlights the essential need for ongoing research into micronutrient supplementation in these high-risk groups.
Read More

Most Useful Reviews

7.5
Improved immunity
108 people found this helpful
One of the best forms of zinc. The capsule size is average and easy to swallow. I noticed significant improvements; my hair grows faster, my skin looks healthier, and my sebum production has decreased. Additionally, my immunity has enhanced, and I no longer catch colds from my sick child. However, it's essential not to overdo it, as too much zinc can lead to copper deficiency and subsequent anaemia.
Read More
6
Supports skin health
13 people found this helpful
Zinc is crucial for the body, acting as a powerful antioxidant that supports hormone production and wound healing. A deficiency can negatively affect skin, hair, and metabolism. Adequate zinc intake, through diet or supplements, can help correct anaemia and skin conditions, while also promoting testosterone formation. A balanced diet is essential for overall health and zinc levels.
Read More
6
Copper is essential
7 people found this helpful
This bioavailable form can be harmful in high doses. Excess zinc over time may deplete copper, leading to anaemia. Copper is essential for forming healthy red blood cells. Zinc is crucial for various bodily functions and helps with acne by balancing cortisol levels, but I found the high dosage too much for me.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 7 Researches
6.6
  • All Researches
We observed an intriguing case involving a 51-year-old woman diagnosed with treatment-resistant schizophrenia (TRS) who developed severe anemia while undergoing clozapine therapy. This case highlights the complex relationship between clozapine, a potent antipsychotic, and zinc deficiency. Through identifying zinc deficiency as a possible contributing factor to the anemia, we explored how zinc supplementation could play a pivotal role in restoring hemoglobin levels.

Following zinc supplementation, we noted impressive improvements in her hemoglobin, allowing the patient to continue her clozapine at a therapeutic dosage. Remarkably, she has shown stability since, with no signs of recurrent anemia. While clozapine can lead to various complications, including anemia, this case suggests that addressing zinc levels may be critical for patients receiving this treatment.

However, we must acknowledge that the exact mechanism linking zinc deficiency and clozapine-related anemia remains unclear. Thus, further investigation is warranted to fully understand this relationship and the potential of zinc in managing anemia, particularly in patients on clozapine.
Read More
9
Zinc deficiency linked to anemia
We explored the connection between zinc deficiency and anemia through the case of an 18-year-old woman who faced a series of health issues, including urinary tract infections and insulin dysfunction. After a thorough assessment, she was diagnosed with zinc deficiency, shedding light on how this overlooked issue can impact overall health.

What stood out to us was the rapid recovery the patient experienced after beginning oral zinc supplementation. Zinc plays a critical role in numerous bodily functions, including immune support and protein regulation. By addressing her deficiency, we observed significant improvement in her symptoms, including anemia.

The patient’s diet contained high levels of substances that were inhibiting her zinc absorption, which likely contributed to her condition. This case emphasizes the importance of recognizing zinc deficiency as a potential underlying cause for unexplained health issues, particularly anemia. Prompt diagnosis and treatment can lead to a complete turnaround in the patient's health.

By sharing this experience, we hope to raise awareness among clinicians about the vital role of zinc in managing anemia and encourage timely interventions for patients showing diverse symptoms.
Read More
8
Zinc improves anaemia outcomes
We set out to explore how zinc, through micronutrient powders (MNPs), influences anaemia in young children, particularly in Bangladesh, where high rates of anaemia persist. In a well-structured trial, we observed children aged 9-11 months receiving daily doses of MNPs for 24 weeks. Initially, a staggering 54.1% of these children had anaemia, characterized by low hemoglobin levels.

At the end of the study, anaemia prevalence decreased to 32.6%, indicating some positive effects of the MNPs, which included zinc as one of their components. However, while we found various factors associated with anaemia—like underweight status and frequent illness—it's crucial to note that we could not isolate the specific impact of zinc on anaemia from other nutritional interventions included in the powders.

Overall, we acknowledged that while MNPs contribute to addressing anaemia, they should be part of a broader strategy that encompasses other factors impacting health and nutrition. This comprehensive approach ensures effective prevention and control of anaemia in vulnerable populations.
Read More
We explored the impact of zinc treatment on anemia, particularly focusing on preterm and low birth weight infants in low- and middle-income countries. Previous evidence suggested a strong correlation between zinc supplementation and the reduction of anemia rates.

Our review revealed that adding zinc, along with other micronutrients, seems to show promising benefits. Specifically, it can help reduce levels of anemia in vulnerable populations, contributing to better health outcomes.

What's important to note is that benefits from zinc supplementation were often accompanied by other nutrients, making it challenging to isolate its specific effectiveness. Nevertheless, the consensus indicates that zinc, along with iron and vitamin A, plays a supportive role in promoting overall growth and reducing complications related to anemia.

Therefore, while we didn't claim that zinc alone is a catch-all solution, it does hold significant promise when combined with a broader nutritional strategy. This highlights the essential need for ongoing research into micronutrient supplementation in these high-risk groups.
Read More
4
Zinc's uncertain effect on anemia
We examined how zinc supplementation affects anemia in people living with HIV who are on antiretroviral therapy. This review included various studies that looked at the relationship between zinc intake and anemia outcomes.

Overall, the findings suggest that zinc supplementation had little to no significant effect on hemoglobin levels, which is one of the key indicators of anemia. Although the study indicated some uncertainty regarding its impact, we found that as serum zinc levels increased by 10 µg/dL, the expected increase in CD4 lymphocyte count slightly decreased.

This means that while zinc may play a role in immune health, its direct effect on alleviating anemia in this population is not clearly defined. It’s important to note that the evidence surrounding zinc and its impact on hemoglobin concentration remains inconclusive, and further research is needed to clarify its role.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 16 Reviews
7.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Improved immunity
108 people found this helpful
One of the best forms of zinc. The capsule size is average and easy to swallow. I noticed significant improvements; my hair grows faster, my skin looks healthier, and my sebum production has decreased. Additionally, my immunity has enhanced, and I no longer catch colds from my sick child. However, it's essential not to overdo it, as too much zinc can lead to copper deficiency and subsequent anaemia.
Read More
6
Supports skin health
13 people found this helpful
Zinc is crucial for the body, acting as a powerful antioxidant that supports hormone production and wound healing. A deficiency can negatively affect skin, hair, and metabolism. Adequate zinc intake, through diet or supplements, can help correct anaemia and skin conditions, while also promoting testosterone formation. A balanced diet is essential for overall health and zinc levels.
Read More
6
Copper is essential
7 people found this helpful
This bioavailable form can be harmful in high doses. Excess zinc over time may deplete copper, leading to anaemia. Copper is essential for forming healthy red blood cells. Zinc is crucial for various bodily functions and helps with acne by balancing cortisol levels, but I found the high dosage too much for me.
Read More
7.5
Fatigue reduction
2 people found this helpful
I struggled with anaemia, so I resorted to supplements for support while in hospital. I feel less tired since I began taking them, and I believe these ingredients are beneficial for anaemia. Once I recover, I’ll switch to a formula with fewer ingredients.
Read More
7.5
Improved immunity
1 people found this helpful
One of the best forms of zinc. The capsules are average-sized and easily swallowed. I noticed a quick improvement in my zinc levels; my hair grew faster, and my skin improved. I also experienced fewer colds from my sick child, which was common before. However, it’s essential not to overuse this supplement, as it could lead to copper deficiency and ultimately, anaemia.
Read More

Frequently Asked Questions

7.5
Fatigue reduction
2 people found this helpful
I struggled with anaemia, so I resorted to supplements for support while in hospital. I feel less tired since I began taking them, and I believe these ingredients are beneficial for anaemia. Once I recover, I’ll switch to a formula with fewer ingredients.
6
Monitor iron levels
This zinc works well, but I closely monitor my iron levels, as it can induce anaemia. I wouldn’t recommend a 50 mg dosage for everyone, as it's therapeutic rather than preventative. I take it after meals to avoid nausea. I alternate between this and iron supplements; within two weeks, my skin feels soft and velvety.
6
Copper is essential
7 people found this helpful
This bioavailable form can be harmful in high doses. Excess zinc over time may deplete copper, leading to anaemia. Copper is essential for forming healthy red blood cells. Zinc is crucial for various bodily functions and helps with acne by balancing cortisol levels, but I found the high dosage too much for me.
7.5
Improved immunity
108 people found this helpful
One of the best forms of zinc. The capsule size is average and easy to swallow. I noticed significant improvements; my hair grows faster, my skin looks healthier, and my sebum production has decreased. Additionally, my immunity has enhanced, and I no longer catch colds from my sick child. However, it's essential not to overdo it, as too much zinc can lead to copper deficiency and subsequent anaemia.
7.5
Improved immunity
1 people found this helpful
One of the best forms of zinc. The capsules are average-sized and easily swallowed. I noticed a quick improvement in my zinc levels; my hair grew faster, and my skin improved. I also experienced fewer colds from my sick child, which was common before. However, it’s essential not to overuse this supplement, as it could lead to copper deficiency and ultimately, anaemia.
7.5
Energy boost
Zinc aids in fighting illnesses and colds. I always keep it on hand. It also helps with my iron deficiency anaemia, boosting my energy and strength significantly.
7.5
Skin and hair benefits
This is my go-to for colds and runny noses, particularly as an antiviral. I also use it alongside iron and Vitamin C for anaemia. Zinc is vital for skin, nails, and hair health. Overall, the price and quality are excellent.
7.5
Reduces zinc deficiency
The best form of zinc for absorption. It’s vital to address zinc deficiency, particularly in cases of anaemia, but do not take iron and zinc together. Zinc helps me through the cold season and improves acne and oily scalp. I take it for three months and then have a break for three months.
7.5
High dosage caution
149 people found this helpful
This is a decent source of zinc. I’ve found Zinc Picolinate absorbs better than Zinc Citrate or Zinc Gluconate. Just be aware that long-term high doses can lead to copper deficiency, resulting in anaemia and neurological issues. I now take it occasionally, as a lower dose or copper supplementation would be better.
8
Zinc improves anaemia outcomes
We set out to explore how zinc, through micronutrient powders (MNPs), influences anaemia in young children, particularly in Bangladesh, where high rates of anaemia persist. In a well-structured trial, we observed children aged 9-11 months receiving daily doses of MNPs for 24 weeks. Initially, a staggering 54.1% of these children had anaemia, characterized by low hemoglobin levels.

At the end of the study, anaemia prevalence decreased to 32.6%, indicating some positive effects of the MNPs, which included zinc as one of their components. However, while we found various factors associated with anaemia—like underweight status and frequent illness—it's crucial to note that we could not isolate the specific impact of zinc on anaemia from other nutritional interventions included in the powders.

Overall, we acknowledged that while MNPs contribute to addressing anaemia, they should be part of a broader strategy that encompasses other factors impacting health and nutrition. This comprehensive approach ensures effective prevention and control of anaemia in vulnerable populations.
We observed an intriguing case involving a 51-year-old woman diagnosed with treatment-resistant schizophrenia (TRS) who developed severe anemia while undergoing clozapine therapy. This case highlights the complex relationship between clozapine, a potent antipsychotic, and zinc deficiency. Through identifying zinc deficiency as a possible contributing factor to the anemia, we explored how zinc supplementation could play a pivotal role in restoring hemoglobin levels.

Following zinc supplementation, we noted impressive improvements in her hemoglobin, allowing the patient to continue her clozapine at a therapeutic dosage. Remarkably, she has shown stability since, with no signs of recurrent anemia. While clozapine can lead to various complications, including anemia, this case suggests that addressing zinc levels may be critical for patients receiving this treatment.

However, we must acknowledge that the exact mechanism linking zinc deficiency and clozapine-related anemia remains unclear. Thus, further investigation is warranted to fully understand this relationship and the potential of zinc in managing anemia, particularly in patients on clozapine.
4
Zinc's uncertain effect on anemia
We examined how zinc supplementation affects anemia in people living with HIV who are on antiretroviral therapy. This review included various studies that looked at the relationship between zinc intake and anemia outcomes.

Overall, the findings suggest that zinc supplementation had little to no significant effect on hemoglobin levels, which is one of the key indicators of anemia. Although the study indicated some uncertainty regarding its impact, we found that as serum zinc levels increased by 10 µg/dL, the expected increase in CD4 lymphocyte count slightly decreased.

This means that while zinc may play a role in immune health, its direct effect on alleviating anemia in this population is not clearly defined. It’s important to note that the evidence surrounding zinc and its impact on hemoglobin concentration remains inconclusive, and further research is needed to clarify its role.
We explored the impact of zinc treatment on anemia, particularly focusing on preterm and low birth weight infants in low- and middle-income countries. Previous evidence suggested a strong correlation between zinc supplementation and the reduction of anemia rates.

Our review revealed that adding zinc, along with other micronutrients, seems to show promising benefits. Specifically, it can help reduce levels of anemia in vulnerable populations, contributing to better health outcomes.

What's important to note is that benefits from zinc supplementation were often accompanied by other nutrients, making it challenging to isolate its specific effectiveness. Nevertheless, the consensus indicates that zinc, along with iron and vitamin A, plays a supportive role in promoting overall growth and reducing complications related to anemia.

Therefore, while we didn't claim that zinc alone is a catch-all solution, it does hold significant promise when combined with a broader nutritional strategy. This highlights the essential need for ongoing research into micronutrient supplementation in these high-risk groups.

References

  1. Thompson L, Arnold C, Peerson J, Long JM, Westcott JLE, et al. Predictors of Anaemia Among Young Children Receiving Daily Micronutrient Powders (MNPs) for 24 Weeks in Bangladesh: A Secondary Analysis of the Zinc in Powders Trial. Matern Child Nutr. 2025. doi:10.1111/mcn.13806
  2. Matsuo-Yamamoto K, Uenishi S, Ishiyama Y, Yamada S, Kitabata Y, et al. Successful Clozapine Treatment for Treatment-Resistant Schizophrenia With Zinc Deficiency Severe Anemia: A Case Report. Neuropsychopharmacol Rep. 2025;45:e12526. doi:10.1002/npr2.12526
  3. Azhar M, Yasin R, Hanif S, Bughio SA, Das JK, et al. Nutritional Management of Low Birth Weight and Preterm Infants in Low- and Low Middle-Income Countries. Neonatology. 2025;122:209. doi:10.1159/000542154
  4. Okoka EM, Kuyebi MA, Oyadiran OT, Okusanya TR, Onaku E, et al. Effect of Micronutrients on HIV-Related Clinical Outcomes Among Adults Living With HIV on Antiretroviral Therapy: Systematic Review and Meta-analysis. Nutr Rev. 2024. doi:10.1093/nutrit/nuae171
  5. Vicente IST, Fleuri LF, Xavier WDS, Guimarães MG, de Carvalho PLPF, et al. The Effects of Dietary Orange Peel Fragments Enriched with Zinc and Vitamins C and E on the Antioxidant and Immune Responses of Nile Tilapia under Stress Conditions. Animals (Basel). 2024;14. doi:10.3390/ani14202962
  6. Inoue M. Zinc Deficiency Presenting With Diverse Symptoms in a Young Patient: A Case Report. Cureus. 2024;16:e66034. doi:10.7759/cureus.66034
  7. Mohammad Shafiee S, Amiri F, Yousefi F, Akbari Nasab N. Pro-Oxidant/ Antioxidant Balance Correlates with Red Blood Cell Indices and Anemia Severity in the Anemic Patients. Rep Biochem Mol Biol. 2024;12:609. doi:10.61186/rbmb.12.4.609
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