Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 28 Researches
7.4
USERS' SCORE
Medium or Average
Based on 7 Reviews
6.5
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Magnesium (from Magnesium Aspartate)
250 mg
60%
Potassium (from Potassium Aspartate)
99 mg
2%
Taurine (Free-Form)
100 mg
†
Top Medical Research Studies
9
Taurine reduces anxiety, alcohol intake
We explored how taurine, a non-essential amino acid found in energy drinks, influences anxiety and alcohol intake in rats. The study involved both alcohol-naïve rats and those with a history of alcohol consumption, allowing us to see how taurine affects different groups.
Our findings showed that when taurine was administered directly into the brain, it significantly reduced alcohol consumption and preference in the alcohol-experienced rats. This suggests that taurine might help lessen the urge to drink in individuals struggling with alcohol use.
Interestingly, we also observed that taurine had an anxiolytic-like effect across all groups, meaning it seemed to reduce anxiety regardless of the rats' previous alcohol exposure. This dual effect highlights taurine's potential as a therapeutic option for anxiety and alcohol-related issues, making it a fascinating subject for further research.
Our findings showed that when taurine was administered directly into the brain, it significantly reduced alcohol consumption and preference in the alcohol-experienced rats. This suggests that taurine might help lessen the urge to drink in individuals struggling with alcohol use.
Interestingly, we also observed that taurine had an anxiolytic-like effect across all groups, meaning it seemed to reduce anxiety regardless of the rats' previous alcohol exposure. This dual effect highlights taurine's potential as a therapeutic option for anxiety and alcohol-related issues, making it a fascinating subject for further research.
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8
We looked into how taurine, a common amino acid found in the brain, affects anxiety levels. Young mice were given different concentrations of taurine (0.25%, 0.5%, and 1%) in their drinking water for six months to see its potential benefits on memory, cognition, and mood.
Throughout the study, we observed that taurine had a significant effect on improving memory performance and reducing signs of anxiety and depression-like behavior in the mice. In addition to these behavioral changes, taurine also appeared to enhance mitochondrial function, which plays a crucial role in energy and cell health within the brain.
Interestingly, we found no significant difference in anxiety reduction between the various doses of taurine. This suggests that even lower amounts of taurine may be effective. Overall, our findings point towards taurine's potential as a therapeutic option for addressing anxiety and related neurological issues, although further research in humans is necessary to confirm these results.
Throughout the study, we observed that taurine had a significant effect on improving memory performance and reducing signs of anxiety and depression-like behavior in the mice. In addition to these behavioral changes, taurine also appeared to enhance mitochondrial function, which plays a crucial role in energy and cell health within the brain.
Interestingly, we found no significant difference in anxiety reduction between the various doses of taurine. This suggests that even lower amounts of taurine may be effective. Overall, our findings point towards taurine's potential as a therapeutic option for addressing anxiety and related neurological issues, although further research in humans is necessary to confirm these results.
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8
Taurine shows promise against anxiety
We explored the potential of taurine and its derivatives to reduce anxiety in rats that experienced developmental lead (Pb) exposure. The study involved carefully controlled experiments with various treatment groups, including a control group and those exposed to different levels of lead. This allowed us to examine how taurine influenced anxiety levels using established methods for testing behavior.
Although lead exposure did not significantly affect locomotor activity, it did cause increased anxiety in the Elevated Plus Maze (EPM) test. Interestingly, we observed that female rats exhibited more anxious behavior compared to males. However, those that received taurine or its derivatives showed improvement, indicating that these compounds may indeed help alleviate anxiety, particularly in females.
The findings suggest that taurine and its derivatives could serve as promising options for anxiety management, paving the way for further research into their effects on mood disorders. Overall, the results reveal exciting possibilities for using taurine-based treatments to support individuals struggling with anxiety.
Although lead exposure did not significantly affect locomotor activity, it did cause increased anxiety in the Elevated Plus Maze (EPM) test. Interestingly, we observed that female rats exhibited more anxious behavior compared to males. However, those that received taurine or its derivatives showed improvement, indicating that these compounds may indeed help alleviate anxiety, particularly in females.
The findings suggest that taurine and its derivatives could serve as promising options for anxiety management, paving the way for further research into their effects on mood disorders. Overall, the results reveal exciting possibilities for using taurine-based treatments to support individuals struggling with anxiety.
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Most Useful Reviews
9
Supports relaxation
1 people found this helpful
Magnesium and potassium aspartate are helpful for relieving anxiety, enhancing sleep quality, and relieving muscle tension. It contains taurine and comes with 120 medium-sized capsules in a jar.
Read More
9
Effective for anxiety
1 people found this helpful
Magnesium and potassium aspartate is effective for alleviating anxiety, enhancing sleep and reducing muscle tension. It also contains taurine, and the jar includes 120 medium-sized capsules.
Read More
7.5
Helps anxiety
3 people found this helpful
Magnesium and potassium aspartate effectively address anxiety, supporting sleep and relieving muscle tension. It also contains taurine and features 120 medium-sized capsules in a jar.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 28 Researches
7.4
- All Researches
9
We examined how magnesium, in combination with ibogaine, affects anxiety in veterans with traumatic brain injuries. This was part of a larger study focusing on the wellbeing of Special Operations Forces veterans, who often suffer from mental health issues like anxiety and PTSD after experiencing head trauma.
The study involved 30 male veterans, primarily with mild brain injuries. Researchers used various assessments, including scales for anxiety, to measure changes before treatment and then again one month afterward. The findings were promising, showing considerable improvements in anxiety levels, as well as in depression and PTSD symptoms.
However, it’s important to note that since magnesium was administered alongside ibogaine, we can’t isolate the effects of magnesium alone on anxiety. Although the results were encouraging, we need more controlled clinical trials to fully understand the safety and effectiveness of magnesium treatment on its own.
Overall, while magnesium may play a role in improving anxiety, further research is essential to clarify its specific impact without the influence of other treatments.
The study involved 30 male veterans, primarily with mild brain injuries. Researchers used various assessments, including scales for anxiety, to measure changes before treatment and then again one month afterward. The findings were promising, showing considerable improvements in anxiety levels, as well as in depression and PTSD symptoms.
However, it’s important to note that since magnesium was administered alongside ibogaine, we can’t isolate the effects of magnesium alone on anxiety. Although the results were encouraging, we need more controlled clinical trials to fully understand the safety and effectiveness of magnesium treatment on its own.
Overall, while magnesium may play a role in improving anxiety, further research is essential to clarify its specific impact without the influence of other treatments.
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We aimed to investigate the potential of a food supplement called Blue Calm®, which contains taurine among other ingredients, in treating anxiety linked to alcohol withdrawal in adult zebrafish. Through various tests, we assessed whether this supplement could have a calming effect when given to zebrafish who were experiencing anxiety due to alcohol withdrawal.
During the study, we established the antioxidant properties of Blue Calm® and observed its sedative effects. Importantly, the supplement showed no signs of toxicity during the testing period. Our findings indicated that all tested dosages of Blue Calm® produced an anxiolytic-like effect, suggesting that taurine and the other components may help alleviate symptoms of anxiety during alcohol withdrawal.
Moreover, we explored the interaction of Blue Calm®'s ingredients with the GABA receptor, a critical component in the regulation of anxiety. Our molecular docking analysis confirmed that the primary compounds, including taurine, have effects on the GABAergic system.
Ultimately, while taurine's individual role was not isolated in this study, the results are promising for its anxiolytic potential as part of the Blue Calm® formulation. This work supports further exploration of taurine and similar compounds for therapeutic uses in managing alcohol-induced anxiety.
During the study, we established the antioxidant properties of Blue Calm® and observed its sedative effects. Importantly, the supplement showed no signs of toxicity during the testing period. Our findings indicated that all tested dosages of Blue Calm® produced an anxiolytic-like effect, suggesting that taurine and the other components may help alleviate symptoms of anxiety during alcohol withdrawal.
Moreover, we explored the interaction of Blue Calm®'s ingredients with the GABA receptor, a critical component in the regulation of anxiety. Our molecular docking analysis confirmed that the primary compounds, including taurine, have effects on the GABAergic system.
Ultimately, while taurine's individual role was not isolated in this study, the results are promising for its anxiolytic potential as part of the Blue Calm® formulation. This work supports further exploration of taurine and similar compounds for therapeutic uses in managing alcohol-induced anxiety.
Read More
9
Taurine reduces anxiety, alcohol intake
We explored how taurine, a non-essential amino acid found in energy drinks, influences anxiety and alcohol intake in rats. The study involved both alcohol-naïve rats and those with a history of alcohol consumption, allowing us to see how taurine affects different groups.
Our findings showed that when taurine was administered directly into the brain, it significantly reduced alcohol consumption and preference in the alcohol-experienced rats. This suggests that taurine might help lessen the urge to drink in individuals struggling with alcohol use.
Interestingly, we also observed that taurine had an anxiolytic-like effect across all groups, meaning it seemed to reduce anxiety regardless of the rats' previous alcohol exposure. This dual effect highlights taurine's potential as a therapeutic option for anxiety and alcohol-related issues, making it a fascinating subject for further research.
Our findings showed that when taurine was administered directly into the brain, it significantly reduced alcohol consumption and preference in the alcohol-experienced rats. This suggests that taurine might help lessen the urge to drink in individuals struggling with alcohol use.
Interestingly, we also observed that taurine had an anxiolytic-like effect across all groups, meaning it seemed to reduce anxiety regardless of the rats' previous alcohol exposure. This dual effect highlights taurine's potential as a therapeutic option for anxiety and alcohol-related issues, making it a fascinating subject for further research.
Read More
9
Taurine alleviates PTSD-related anxiety
We explored the effects of taurine, a naturally occurring nutrient, on anxiety related to post-traumatic stress disorder (PTSD) in rats. The study involved exposing these animals to stressors followed by a re-stress phase to mimic PTSD symptoms. During this period, we administered various doses of taurine along with a standard antidepressant, paroxetine.
Our findings showed that taurine supplementation significantly improved PTSD-like symptoms in the rats, particularly in reducing anxiety and hyperarousal. In particular, the medium and high doses of taurine demonstrated notable success, as they not only eased anxiety but also enhanced spatial recognition. Additionally, taurine helped restore normal levels of certain key hormones and ions in the blood, which are often disrupted by stress.
Ultimately, our research indicates that taurine may play a beneficial role in managing anxiety associated with PTSD, especially given its impact on the underlying mechanisms like potassium homeostasis and mitochondrial function. This suggests a promising avenue for future treatments targeting anxiety disorders in broader settings.
Our findings showed that taurine supplementation significantly improved PTSD-like symptoms in the rats, particularly in reducing anxiety and hyperarousal. In particular, the medium and high doses of taurine demonstrated notable success, as they not only eased anxiety but also enhanced spatial recognition. Additionally, taurine helped restore normal levels of certain key hormones and ions in the blood, which are often disrupted by stress.
Ultimately, our research indicates that taurine may play a beneficial role in managing anxiety associated with PTSD, especially given its impact on the underlying mechanisms like potassium homeostasis and mitochondrial function. This suggests a promising avenue for future treatments targeting anxiety disorders in broader settings.
Read More
9
In our study, we delved into how taurine, a naturally occurring antioxidant, impacts anxiety, particularly in the context of stress-induced behavioral changes. We used a group of Swiss albino male mice, which were subjected to 6 hours of restraint stress daily for 28 days to simulate chronic stress conditions. The mice were divided into four groups: a control group, a restraint stress group, a group receiving taurine while undergoing stress, and a taurine-only control group.
Our findings revealed that taurine treatment noticeably improved the anxiety-related behaviors of the stressed mice. We assessed this by using several tests designed to gauge behavioral responses, such as the elevated plus-maze and the forced swim test. In those subjected to restraint stress, taurine notably countered the negative effects, restoring normal behavior patterns.
We also found that taurine helped reduce oxidative stress and neuroinflammation in the hippocampus, a key brain area for mood regulation. This is significant since chronic stress can lead to various neurochemical imbalances that contribute to anxiety and depression. By inhibiting certain proteins linked to these processes, taurine demonstrated a protective effect against behavioral anomalies linked to stress.
Thus, our study presents taurine as a promising agent for alleviating anxiety associated with stress, potentially paving the way for future therapies targeting stress-induced conditions.
Our findings revealed that taurine treatment noticeably improved the anxiety-related behaviors of the stressed mice. We assessed this by using several tests designed to gauge behavioral responses, such as the elevated plus-maze and the forced swim test. In those subjected to restraint stress, taurine notably countered the negative effects, restoring normal behavior patterns.
We also found that taurine helped reduce oxidative stress and neuroinflammation in the hippocampus, a key brain area for mood regulation. This is significant since chronic stress can lead to various neurochemical imbalances that contribute to anxiety and depression. By inhibiting certain proteins linked to these processes, taurine demonstrated a protective effect against behavioral anomalies linked to stress.
Thus, our study presents taurine as a promising agent for alleviating anxiety associated with stress, potentially paving the way for future therapies targeting stress-induced conditions.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 7 Reviews
6.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Supports relaxation
1 people found this helpful
Magnesium and potassium aspartate are helpful for relieving anxiety, enhancing sleep quality, and relieving muscle tension. It contains taurine and comes with 120 medium-sized capsules in a jar.
Read More
9
Effective for anxiety
1 people found this helpful
Magnesium and potassium aspartate is effective for alleviating anxiety, enhancing sleep and reducing muscle tension. It also contains taurine, and the jar includes 120 medium-sized capsules.
Read More
7.5
Helps anxiety
3 people found this helpful
Magnesium and potassium aspartate effectively address anxiety, supporting sleep and relieving muscle tension. It also contains taurine and features 120 medium-sized capsules in a jar.
Read More
7.5
Alleviates tension
1 people found this helpful
Magnesium and potassium aspartate aids in deterring anxiety, promotes sleep, and diminishes muscle tension. With taurine included, you'll find 120 medium-sized capsules in the jar.
Read More
7.5
Muscle tension relief
Magnesium and potassium aspartate works well for relieving anxiety, supporting sleep, and alleviating muscle tension. Also containing taurine, the jar has 120 medium-sized capsules.
Read More
Frequently Asked Questions
9
Supports relaxation
1 people found this helpful
Magnesium and potassium aspartate are helpful for relieving anxiety, enhancing sleep quality, and relieving muscle tension. It contains taurine and comes with 120 medium-sized capsules in a jar.
9
Effective for anxiety
1 people found this helpful
Magnesium and potassium aspartate is effective for alleviating anxiety, enhancing sleep and reducing muscle tension. It also contains taurine, and the jar includes 120 medium-sized capsules.
7.5
Helps anxiety
3 people found this helpful
Magnesium and potassium aspartate effectively address anxiety, supporting sleep and relieving muscle tension. It also contains taurine and features 120 medium-sized capsules in a jar.
7
We conducted a systematic review to evaluate how magnesium might help with anxiety. As self-treatment with supplements grows in popularity, we focused on the clinical evidence surrounding magnesium’s effects on anxiety and sleep disorders.
Through our thorough search, we found 15 studies that fit our strict criteria. Most of these studies showed at least some improvement in either anxiety levels or sleep quality. In fact, five out of eight studies looking at sleep-related outcomes noted positive changes, while five out of seven studies focused on anxiety reported improvements in self-reported anxiety.
Despite the encouraging findings, we have to approach these results with caution. The studies varied in terms of dosage, formulation, and duration of magnesium treatment. Plus, some included other active ingredients that make it hard to know magnesium’s exact impact. Interestingly, two of the studies that didn’t show improvement involved populations with other health concerns, highlighting the need for further investigation.
Overall, it seems like magnesium might be a useful supplement for those dealing with mild anxiety, especially if they have low magnesium levels to begin with. However, larger and more rigorous trials are essential to truly confirm its effectiveness and determine the best types and doses for use.
Through our thorough search, we found 15 studies that fit our strict criteria. Most of these studies showed at least some improvement in either anxiety levels or sleep quality. In fact, five out of eight studies looking at sleep-related outcomes noted positive changes, while five out of seven studies focused on anxiety reported improvements in self-reported anxiety.
Despite the encouraging findings, we have to approach these results with caution. The studies varied in terms of dosage, formulation, and duration of magnesium treatment. Plus, some included other active ingredients that make it hard to know magnesium’s exact impact. Interestingly, two of the studies that didn’t show improvement involved populations with other health concerns, highlighting the need for further investigation.
Overall, it seems like magnesium might be a useful supplement for those dealing with mild anxiety, especially if they have low magnesium levels to begin with. However, larger and more rigorous trials are essential to truly confirm its effectiveness and determine the best types and doses for use.
7
We examined the link between magnesium oxide and anxiety-like behavior in mice. The research focused on how a specific type of bacteria in the gut, known as sulfate-reducing bacteria (SRB), might contribute to anxiety. When we introduced these bacteria into the mice, they exhibited increased signs of anxiety, which we measured using a test called the open field test.
Next, we explored the effect of magnesium oxide on the growth of these bacteria in both lab settings and in real-life scenarios involving psychological stress, specifically using a water avoidance stress model. Remarkably, we found that magnesium oxide effectively inhibited the growth of SRB and the production of a byproduct called hydrogen sulfide in a dose-dependent manner.
Mice subjected to stress developed an overgrowth of SRB and displayed amplified anxiety-like behavior. However, those fed a magnesium oxide-enriched diet showed reduced levels of both SRB and anxiety. Our findings suggest that magnesium may play a significant role in mitigating anxiety by altering gut bacteria dynamics.
Next, we explored the effect of magnesium oxide on the growth of these bacteria in both lab settings and in real-life scenarios involving psychological stress, specifically using a water avoidance stress model. Remarkably, we found that magnesium oxide effectively inhibited the growth of SRB and the production of a byproduct called hydrogen sulfide in a dose-dependent manner.
Mice subjected to stress developed an overgrowth of SRB and displayed amplified anxiety-like behavior. However, those fed a magnesium oxide-enriched diet showed reduced levels of both SRB and anxiety. Our findings suggest that magnesium may play a significant role in mitigating anxiety by altering gut bacteria dynamics.
8
Magnesium's role in anxiety treatment
We explored the effects of magnesium sulfate and labetalol on managing pregnancy-induced hypertension (PIH) and their potential influence on anxiety and depression among patients. In our study, we examined data from patients diagnosed with PIH from July 2020 to July 2023 at two hospitals in Chengdu, China.
Among the 219 participants, we found that 36.1% experienced anxiety and depression. We divided patients into two groups based on treatment: one group received magnesium sulfate and labetalol, while the other group received standard treatment. It was notable that those in the magnesium sulfate and labetalol group reported significant improvements in anxiety and depression levels, as measured by the Edinburgh Postnatal Depression Scale and the Generalized Anxiety Disorder 7 scale.
However, when evaluating blood pressure control, the effectiveness was similar across both groups, which means the treatment did not significantly impact blood pressure outcomes. Overall, this research points to the possibility that magnesium sulfate and labetalol can not only help manage high blood pressure in pregnant women but may also indirectly alleviate feelings of anxiety and depression.
Among the 219 participants, we found that 36.1% experienced anxiety and depression. We divided patients into two groups based on treatment: one group received magnesium sulfate and labetalol, while the other group received standard treatment. It was notable that those in the magnesium sulfate and labetalol group reported significant improvements in anxiety and depression levels, as measured by the Edinburgh Postnatal Depression Scale and the Generalized Anxiety Disorder 7 scale.
However, when evaluating blood pressure control, the effectiveness was similar across both groups, which means the treatment did not significantly impact blood pressure outcomes. Overall, this research points to the possibility that magnesium sulfate and labetalol can not only help manage high blood pressure in pregnant women but may also indirectly alleviate feelings of anxiety and depression.
7
In our quest to understand how magnesium influences anxiety, we conducted a randomized double-blind controlled trial involving 120 adults diagnosed with major depressive disorder (MDD). Participants took either a combination of probiotics, magnesium orotate, and coenzyme Q10 or a placebo for eight weeks.
At the end of the treatment period, we observed that those taking the combination showed significantly lower rates of major depressive episodes compared to those taking the placebo. However, this difference did not persist by the 8-week follow-up. While there was a notable reduction in self-reported symptoms of anxiety and stress during the treatment, this result also lacks long-term significance.
Ultimately, while our findings suggest that magnesium in combination with probiotics and coenzyme Q10 might help alleviate anxiety symptoms for a brief period, the persistent effects are unclear as we found no enduring benefits in the longer term.
At the end of the treatment period, we observed that those taking the combination showed significantly lower rates of major depressive episodes compared to those taking the placebo. However, this difference did not persist by the 8-week follow-up. While there was a notable reduction in self-reported symptoms of anxiety and stress during the treatment, this result also lacks long-term significance.
Ultimately, while our findings suggest that magnesium in combination with probiotics and coenzyme Q10 might help alleviate anxiety symptoms for a brief period, the persistent effects are unclear as we found no enduring benefits in the longer term.
References
- Strodl E, Bambling M, Parnam S, Ritchie G, Cramb S, et al. Probiotics and magnesium orotate for the treatment of major depressive disorder: a randomised double blind controlled trial. Sci Rep. 2024;14:20841. doi:10.1038/s41598-024-71093-z
- Coffman CN, Carroll-Portillo A, Alcock J, Singh SB, Rumsey K, et al. Magnesium Oxide Reduces Anxiety-like Behavior in Mice by Inhibiting Sulfate-Reducing Bacteria. Microorganisms. 2024;12. doi:10.3390/microorganisms12071429
- Rawji A, Peltier MR, Mourtzanakis K, Awan S, Rana J, et al. Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review. Cureus. 2024;16:e59317. doi:10.7759/cureus.59317
- Wang S, Zhang J, Zhu T, Xie X, Xia X, et al. Efficacy of Magnesium Sulfate and Labetalol in the Treatment of Pregnancy-Induced Hypertension and Its Effect on Anxiety and Depression: A Retrospective Cohort Study. Alpha Psychiatry. 2024;25:243. doi:10.5152/alphapsychiatry.2024.231342
- Abdel Rady MM, Osman AM, Abo Elfadl GM, Ahmed HM, Sayed S, et al. Effects of intravenous single-bolus lidocaine infusion versus intravenous single-bolus magnesium sulfate infusion on postoperative pain, emotional status, and quality of life in patients undergoing spine fusion surgery: a randomized study. Minerva Anestesiol. 2024;90:397. doi:10.23736/S0375-9393.24.17868-6
- Cetin A, Ozdemir E, Golgeli A, Taskiran AS, Karabulut S, et al. The effect of magnesium sulfate on memory and anxiety-like behavior in a rat model: an investigation of its neuronal molecular mechanisms. Neurol Res. 2024;46:752. doi:10.1080/01616412.2024.2352234
- Mititelu-Tartau L, Bogdan M, Pavel LL, Rezus C, Foia CI, et al. Anxiolytic-like Activity, Antioxidant Properties, and Facilitatory Effects on the Short-Term Memory Retention of Molsidomine in Rats. Life (Basel). 2024;14. doi:10.3390/life14030306
- Cherian KN, Keynan JN, Anker L, Faerman A, Brown RE, et al. Magnesium-ibogaine therapy in veterans with traumatic brain injuries. Nat Med. 2024;30:373. doi:10.1038/s41591-023-02705-w
- Pickering G, Noah L, Pereira B, Goubayon J, Leray V, et al. Assessing brain function in stressed healthy individuals following the use of a combination of green tea, Rhodiola, magnesium, and B vitamins: an fMRI study. Front Nutr. 2023;10:1211321. doi:10.3389/fnut.2023.1211321
- Hajri L, Othman H, Ghodbane S, Sakly M, Abdelmelek H, et al. Neuroprotective effects of magnesium against stress induced by hydrogen peroxide in Wistar rat. Biomarkers. 2023;28:538. doi:10.1080/1354750X.2023.2246104
- Li Z, Chen K, Shao Q, Lu H, Zhang X, et al. Nanoparticulate MgH ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress. J Neuroinflammation. 2023;20:16. doi:10.1186/s12974-023-02696-y
- Proskurnina EV, Liaukovich KM, Bychkovskaya LS, Mikheev IV, Alshanskaia EI, et al. Salivary Antioxidant Capacity and Magnesium in Generalized Anxiety Disorder. Metabolites. 2023;13. doi:10.3390/metabo13010073
- Rezaei H, Wang HW, Tian W, Zhao J, Najibi A, et al. Long-term taurine supplementation regulates brain mitochondrial dynamics in mice. Basic Clin Pharmacol Toxicol. 2025;136:e14101. doi:10.1111/bcpt.14101
- Marques LDS, Rocha YMD, Nascimento GAD, Santos SAAR, Vieira NCG, et al. Potential of the Blue Calm® food supplement in the treatment of alcohol withdrawal-induced anxiety in adult zebrafish (Danio rerio). Neurochem Int. 2024;175:105706. doi:10.1016/j.neuint.2024.105706
- Miranda-Páez A, Marichal-Cancino BA, Sánchez-Castillo H, Vázquez-León P. Acute taurine reduced alcohol intake and preference in alcohol-experienced, but not in alcohol-näive rats by central mechanisms. Behav Brain Res. 2024;463:114892. doi:10.1016/j.bbr.2024.114892
- Ichikawa S, Abe R, Fujimoto H, Higashi K, Zang L, et al. administration alters zebrafish anxiety-like behavior gut microbial taurine metabolism. Front Microbiol. 2023;14:1079187. doi:10.3389/fmicb.2023.1079187
- Cruz GB, Vasquez MA, Cabañas E, Joseph JN, Skeen JC, et al. Developmental Lead Exposure in Rats Causes Sex-Dependent Changes in Neurobiological and Anxiety-Like Behaviors that Are Improved by Taurine Co-treatment. Adv Exp Med Biol. 2022;1370:461. doi:10.1007/978-3-030-93337-1_43
- Neuwirth LS, Emenike BU, Cruz GB, Cabañas E, Vasquez MA, et al. Taurine-Derived Compounds Produce Anxiolytic Effects in Rats Following Developmental Lead Exposure. Adv Exp Med Biol. 2022;1370:445. doi:10.1007/978-3-030-93337-1_42
- Chudzik A, Słowik T, Kochalska K, Pankowska A, Łazorczyk A, et al. Continuous Ingestion of JB-1 during Chronic Stress Ensures Neurometabolic and Behavioural Stability in Rats. Int J Mol Sci. 2022;23. doi:10.3390/ijms23095173
- Stefanello FV, Müller TE, Franscescon F, Quadros VA, Souza TP, et al. Taurine modulates behavioral effects of intermittent ethanol exposure without changing brain monoamine oxidase activity in zebrafish: Attenuation of shoal- and anxiety-like responses, and abolishment of memory acquisition deficit. Pharmacol Biochem Behav. 2021;209:173256. doi:10.1016/j.pbb.2021.173256
- Bhattacharjee A, Prajapati SK, Krishnamurthy S. Supplementation of taurine improves ionic homeostasis and mitochondrial function in the rats exhibiting post-traumatic stress disorder-like symptoms. Eur J Pharmacol. 2021;908:174361. doi:10.1016/j.ejphar.2021.174361
- Pyrzanowska J, Joniec-Maciejak I, Blecharz-Klin K, Piechal A, Mirowska-Guzel D, et al. Aspalathus linearis infusion affects hole-board test behaviour and amino acid concentration in the brain. Neurosci Lett. 2021;747:135680. doi:10.1016/j.neulet.2021.135680
- Pulcinelli RR, de Paula LF, Nietiedt NA, Bandiera S, Hansen AW, et al. Taurine enhances voluntary alcohol intake and promotes anxiolytic-like behaviors in rats. Alcohol. 2020;88:55. doi:10.1016/j.alcohol.2020.07.004
- Jangra A, Rajput P, Dwivedi DK, Lahkar M. Amelioration of Repeated Restraint Stress-Induced Behavioral Deficits and Hippocampal Anomalies with Taurine Treatment in Mice. Neurochem Res. 2020;45:731. doi:10.1007/s11064-019-02945-8
- Fontana BD, Duarte T, Müller TE, Canzian J, Ziani PR, et al. Concomitant taurine exposure counteracts ethanol-induced changes in locomotor and anxiety-like responses in zebrafish. Psychopharmacology (Berl). 2020;237:735. doi:10.1007/s00213-019-05410-0
- Francisco EDS, Mendes-da-Silva RF, de Castro CBL, Soares GSF, Guedes RCA. Taurine/Pilocarpine Interaction in the Malnourished Rat Brain: A Behavioral, Electrophysiological, and Immunohistochemical Analysis. Front Neurosci. 2019;13:981. doi:10.3389/fnins.2019.00981
- Park E, Elidrissi A, Schuller-Levis G, Chadman KK. Taurine Partially Improves Abnormal Anxiety in Taurine-Deficient Mice. Adv Exp Med Biol. 2019;1155:905. doi:10.1007/978-981-13-8023-5_76
- Neuwirth LS, Emenike BU, Barrera ED, Hameed N, Rubi S, et al. Assessing the Anxiolytic Properties of Taurine-Derived Compounds in Rats Following Developmental Lead Exposure: A Neurodevelopmental and Behavioral Pharmacological Pilot Study. Adv Exp Med Biol. 2019;1155:801. doi:10.1007/978-981-13-8023-5_69
