Last update
5/4/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 43 Researches
7.8
USERS' SCORE
Good
Based on 13 Reviews
8
Supplement Facts
Serving Size: 1 Wafer
Amount Per Serving
%DV
Total Carbohydrate
1 g
<1%**
Total Sugars
<1 g
***
Includes <1 g Added Sugars
1%**
Lactobacillus BlendWhich contains 1 Billion Live Culture CFULactobacillus acidophilus La-14® and Bifidobacterium lactis BI-04
4.5 mg
***
Top Medical Research Studies
9
We explored the impact of Bifidobacterium lactis BLa80 on constipation using mice that were induced with functional constipation through loperamide treatment. In our study, we compared BLa80 to a blank group and a positive control.
The results indicated that BLa80 improved intestinal movement, increased fecal moisture, and balanced gut bacteria. It also helped regulate important gut hormones. Overall, BLa80 shows promise as a potential new option for relieving constipation in functional foods.
The results indicated that BLa80 improved intestinal movement, increased fecal moisture, and balanced gut bacteria. It also helped regulate important gut hormones. Overall, BLa80 shows promise as a potential new option for relieving constipation in functional foods.
Read More
9
We investigated the effects of Bifidobacterium lactis subsp. TG11 on loperamide-induced constipation in mice. The mice were grouped into control and treatment categories, receiving different doses of the probiotic.
After treatment, those receiving TG11 showed improved intestinal motility and maintained better fecal water content. Notably, the probiotic also positively affected gut microbiota, increasing beneficial bacteria and promoting short-chain fatty acid production.
Overall, Bifidobacterium lactis TG11 appears effective in alleviating constipation, potentially by enhancing gut health.
After treatment, those receiving TG11 showed improved intestinal motility and maintained better fecal water content. Notably, the probiotic also positively affected gut microbiota, increasing beneficial bacteria and promoting short-chain fatty acid production.
Overall, Bifidobacterium lactis TG11 appears effective in alleviating constipation, potentially by enhancing gut health.
Read More
9
We assessed the effectiveness of Bifidobacterium animalis subsp. lactis XLTG11 in helping children with functional constipation through a well-structured study with a randomized, double-blinded, placebo-controlled design. The children were split into two groups: one received the probiotic treatment alongside conventional care, while the other did not.
Over the treatment period, we saw a consistent increase in bowel movements in the group taking the probiotic, showing higher fecal frequency compared to the control group. Additionally, the beneficial bacteria in their guts improved, which suggests that this treatment is a promising approach for managing constipation in children.
Over the treatment period, we saw a consistent increase in bowel movements in the group taking the probiotic, showing higher fecal frequency compared to the control group. Additionally, the beneficial bacteria in their guts improved, which suggests that this treatment is a promising approach for managing constipation in children.
Read More
Most Useful Reviews
9
Children's relief
4 people found this helpful
Children are delighted! I keep a close eye on my children's gastrointestinal health. These tablets have a subtle fruity flavour, which my children enjoy, making them eager to take them. I give one tablet daily. Although they are described as "wafers", they resemble flat tablets, akin to ascorbic acid. With a billion acidophilus per tablet, the quality is good. The packaging is a simple plastic jar with a convenient lid. Constipation is no longer an issue for my youngest son. If you find this review helpful, please give it a thumbs up. Wishing health and joy to all children on Earth!
Read More
7.5
Improved bowel movement
1 people found this helpful
It’s good; I now have regular bowel movements. I was usually constipated, but since taking this, I feel much better.
Read More
7.5
Supports digestion
1 people found this helpful
This is a good quality supplement for its price, with an excellent size and a rich artificial strawberry flavour that is quite sweet, making it easy for children to take. It significantly aided my digestion and reduced constipation attacks without causing any pain or side effects. The cute, sealed package is an added bonus; I recommend it.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 43 Researches
7.8
- All Researches
9.5
Cultured milk drink relieves constipation
We explored the impact of a cultured milk drink containing Lactobacillus acidophilus on constipation symptoms in adults with constipation-predominant irritable bowel syndrome (IBS-C). Over 30 days, 77 participants drank this yogurt-like beverage daily.
Post-treatment, a staggering 97.4% of participants reported improvement in their symptoms, including decreased intestinal transit time and lower fecal pH. Notably, the levels of inflammatory cytokines also dropped significantly, suggesting potential benefits of this treatment for IBS-C patients.
Post-treatment, a staggering 97.4% of participants reported improvement in their symptoms, including decreased intestinal transit time and lower fecal pH. Notably, the levels of inflammatory cytokines also dropped significantly, suggesting potential benefits of this treatment for IBS-C patients.
Read More
9
Probiotics improve constipation symptoms
We conducted a randomized, placebo-controlled trial involving 92 children aged 4 to 12 with functional constipation. Over four weeks, we provided one group with a probiotic chewable tablet containing specific strains and compared their experiences to a placebo group.
The findings were promising; the probiotic group reported a significant improvement in stool frequency and a decrease in hard defecation. Specifically, hard stools decreased from 43% to 14%, while normal defecation increased from 56% to 80%. This study highlights the potential of probiotics as a valuable option for managing constipation in children.
The findings were promising; the probiotic group reported a significant improvement in stool frequency and a decrease in hard defecation. Specifically, hard stools decreased from 43% to 14%, while normal defecation increased from 56% to 80%. This study highlights the potential of probiotics as a valuable option for managing constipation in children.
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9
We evaluated how lactobacillus acidophilus, both alone and in a mix with other bacteria, might relieve constipation caused by loperamide in rats. Over 14 days, we noticed that the groups receiving probiotics had significantly heavier and wetter stools compared to control animals.
Notably, the CKDBP group, a blend of multiple bacteria, showed the greatest improvement in intestinal transit. Measures like mucosal length and mucus secretion were also significantly enhanced in all probiotic-treated groups, highlighting their potential to alleviate constipation symptoms effectively.
Notably, the CKDBP group, a blend of multiple bacteria, showed the greatest improvement in intestinal transit. Measures like mucosal length and mucus secretion were also significantly enhanced in all probiotic-treated groups, highlighting their potential to alleviate constipation symptoms effectively.
Read More
9
We explored the impact of Bifidobacterium lactis BLa80 on constipation using mice that were induced with functional constipation through loperamide treatment. In our study, we compared BLa80 to a blank group and a positive control.
The results indicated that BLa80 improved intestinal movement, increased fecal moisture, and balanced gut bacteria. It also helped regulate important gut hormones. Overall, BLa80 shows promise as a potential new option for relieving constipation in functional foods.
The results indicated that BLa80 improved intestinal movement, increased fecal moisture, and balanced gut bacteria. It also helped regulate important gut hormones. Overall, BLa80 shows promise as a potential new option for relieving constipation in functional foods.
Read More
9
We investigated the effects of Bifidobacterium lactis subsp. TG11 on loperamide-induced constipation in mice. The mice were grouped into control and treatment categories, receiving different doses of the probiotic.
After treatment, those receiving TG11 showed improved intestinal motility and maintained better fecal water content. Notably, the probiotic also positively affected gut microbiota, increasing beneficial bacteria and promoting short-chain fatty acid production.
Overall, Bifidobacterium lactis TG11 appears effective in alleviating constipation, potentially by enhancing gut health.
After treatment, those receiving TG11 showed improved intestinal motility and maintained better fecal water content. Notably, the probiotic also positively affected gut microbiota, increasing beneficial bacteria and promoting short-chain fatty acid production.
Overall, Bifidobacterium lactis TG11 appears effective in alleviating constipation, potentially by enhancing gut health.
Read More
User Reviews
USERS' SCORE
Good
Based on 13 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Children's relief
4 people found this helpful
Children are delighted! I keep a close eye on my children's gastrointestinal health. These tablets have a subtle fruity flavour, which my children enjoy, making them eager to take them. I give one tablet daily. Although they are described as "wafers", they resemble flat tablets, akin to ascorbic acid. With a billion acidophilus per tablet, the quality is good. The packaging is a simple plastic jar with a convenient lid. Constipation is no longer an issue for my youngest son. If you find this review helpful, please give it a thumbs up. Wishing health and joy to all children on Earth!
Read More
7.5
Improved bowel movement
1 people found this helpful
It’s good; I now have regular bowel movements. I was usually constipated, but since taking this, I feel much better.
Read More
7.5
Supports digestion
1 people found this helpful
This is a good quality supplement for its price, with an excellent size and a rich artificial strawberry flavour that is quite sweet, making it easy for children to take. It significantly aided my digestion and reduced constipation attacks without causing any pain or side effects. The cute, sealed package is an added bonus; I recommend it.
Read More
9
Gastrointestinal help
They are tasty and help relieve constipation while improving gastrointestinal absorption.
Read More
9
Children's digestion enhanced
I give this to my children first thing in the morning to aid their digestion. My daughter often suffers from constipation, and the quality of this product is excellent. The taste is delightful, making it a good nutritional supplement that provides benefits.
Read More
Frequently Asked Questions
7.5
Improved bowel movement
1 people found this helpful
It’s good; I now have regular bowel movements. I was usually constipated, but since taking this, I feel much better.
7.5
Stomach issues relief
These chewable tablets are delicious and have significantly improved my stomach problems. They aid in easing constipation effectively.
9
Children's relief
4 people found this helpful
Children are delighted! I keep a close eye on my children's gastrointestinal health. These tablets have a subtle fruity flavour, which my children enjoy, making them eager to take them. I give one tablet daily. Although they are described as "wafers", they resemble flat tablets, akin to ascorbic acid. With a billion acidophilus per tablet, the quality is good. The packaging is a simple plastic jar with a convenient lid. Constipation is no longer an issue for my youngest son. If you find this review helpful, please give it a thumbs up. Wishing health and joy to all children on Earth!
7.5
Supports digestion
1 people found this helpful
This is a good quality supplement for its price, with an excellent size and a rich artificial strawberry flavour that is quite sweet, making it easy for children to take. It significantly aided my digestion and reduced constipation attacks without causing any pain or side effects. The cute, sealed package is an added bonus; I recommend it.
7.5
Good for kids
1 people found this helpful
These probiotics are excellent! I've always taken probiotics to avoid constipation, and this one suits kids perfectly due to its strawberry flavour. I'm pleased with my choice.
6
Caution advised
These chewable tablets have a slight strawberry flavour but can be powdery. They may cause loose stools if overconsumed, so those who rarely experience constipation should be cautious.
9
Gastrointestinal help
They are tasty and help relieve constipation while improving gastrointestinal absorption.
7
We explored the effects of two different probiotic formulations designed to tackle functional constipation in adults. Participants took an oral sachet daily for 30 days in a randomized, double-blind trial.
Both probiotic mixes improved constipation symptoms by increasing the frequency of bowel movements and enhancing stool quality. However, no significant differences were found among the treatment groups. Overall, the probiotics were safe, with only one report of abdominal pain in a participant.
Both probiotic mixes improved constipation symptoms by increasing the frequency of bowel movements and enhancing stool quality. However, no significant differences were found among the treatment groups. Overall, the probiotics were safe, with only one report of abdominal pain in a participant.
7
We studied the effects of multistrain probiotics on constipation in elderly nursing home residents. Sixty participants took either a specific probiotic mixture or a placebo over 12 weeks in a double-blind setup.
While there was a slight but not statistically significant increase in stool frequency overall, those receiving probiotics showed a notable increase in stool frequency post-day 71 when laxative use was considered.
Overall, the probiotics were well tolerated and deemed safe for treating functional constipation in this population.
While there was a slight but not statistically significant increase in stool frequency overall, those receiving probiotics showed a notable increase in stool frequency post-day 71 when laxative use was considered.
Overall, the probiotics were well tolerated and deemed safe for treating functional constipation in this population.
9.5
Cultured milk drink relieves constipation
We explored the impact of a cultured milk drink containing Lactobacillus acidophilus on constipation symptoms in adults with constipation-predominant irritable bowel syndrome (IBS-C). Over 30 days, 77 participants drank this yogurt-like beverage daily.
Post-treatment, a staggering 97.4% of participants reported improvement in their symptoms, including decreased intestinal transit time and lower fecal pH. Notably, the levels of inflammatory cytokines also dropped significantly, suggesting potential benefits of this treatment for IBS-C patients.
Post-treatment, a staggering 97.4% of participants reported improvement in their symptoms, including decreased intestinal transit time and lower fecal pH. Notably, the levels of inflammatory cytokines also dropped significantly, suggesting potential benefits of this treatment for IBS-C patients.
References
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- Šola KF, Vladimir-Knežević S, Hrabač P, Mucalo I, Saso L, et al. The effect of multistrain probiotics on functional constipation in the elderly: a randomized controlled trial. Eur J Clin Nutr. 2022;76:1675. 10.1038/s41430-022-01189-0
- Lydia A, Indra TA, Rizka A, Abdullah M. The effects of synbiotics on indoxyl sulphate level, constipation, and quality of life associated with constipation in chronic haemodialysis patients: a randomized controlled trial. BMC Nephrol. 2022;23:259. 10.1186/s12882-022-02890-9
- Mokhtar NM, Jaafar NM, Alfian E, Mohd Rathi ND, Abdul Rani R, et al. Clinical assessment and cytokines level in constipation-predominant irritable bowel syndrome participants treated with Lactobacillus-containing cultured milk drink. Acta Gastroenterol Belg. 2021;84:585. 10.51821/84.4.009
- Martoni CJ, Evans M, Chow CT, Chan LS, Leyer G. Impact of a probiotic product on bowel habits and microbial profile in participants with functional constipation: A randomized controlled trial. J Dig Dis. 2019;20:435. 10.1111/1751-2980.12797
- Airaksinen K, Yeung N, Lyra A, Lahtinen SJ, Huttunen T, et al. The effect of a probiotic blend on gastrointestinal symptoms in constipated patients: a double blind, randomised, placebo controlled 2-week trial. Benef Microbes. 2019;10:617. 10.3920/BM2018.0163
- Magro DO, de Oliveira LM, Bernasconi I, Ruela Mde S, Credidio L, et al. Effect of yogurt containing polydextrose, Lactobacillus acidophilus NCFM and Bifidobacterium lactis HN019: a randomized, double-blind, controlled study in chronic constipation. Nutr J. 2014;13:75. 10.1186/1475-2891-13-75
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- Tabbers MM, de Milliano I, Roseboom MG, Benninga MA. Is Bifidobacterium breve effective in the treatment of childhood constipation? Results from a pilot study. Nutr J. 2011;10:19. 10.1186/1475-2891-10-19
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- Drouault-Holowacz S, Bieuvelet S, Burckel A, Cazaubiel M, Dray X, et al. A double blind randomized controlled trial of a probiotic combination in 100 patients with irritable bowel syndrome. Gastroenterol Clin Biol. 2008;32:147. 10.1016/j.gcb.2007.06.001
- Astegiano M, Pellicano R, Terzi E, Simondi D, Rizzetto M. Treatment of irritable bowel syndrome. A case control experience. Minerva Gastroenterol Dietol. 2006;52:359. PubMed
- Tsuchiya J, Barreto R, Okura R, Kawakita S, Fesce E, et al. Single-blind follow-up study on the effectiveness of a symbiotic preparation in irritable bowel syndrome. Chin J Dig Dis. 2004;5:169. PubMed
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- Liao Y, Wang Y, Huang W, Wang J, Guo M, et al. L. acidophilus/L. johnsonii ratio affects slow transit constipation in rats. Sci Rep. 2024;14:21088. 10.1038/s41598-024-71945-8
- Gan D, Chen J, Tang X, Xiao L, Martoni CJ, et al. Impact of a probiotic chewable tablet on stool habits and microbial profile in children with functional constipation: A randomized controlled clinical trial. Front Microbiol. 2022;13:985308. 10.3389/fmicb.2022.985308
- Lin B, Zhao F, Liu Y, Wu X, Feng J, et al. Randomized Clinical Trial: Probiotics Alleviated Oral-Gut Microbiota Dysbiosis and Thyroid Hormone Withdrawal-Related Complications in Thyroid Cancer Patients Before Radioiodine Therapy Following Thyroidectomy. Front Endocrinol (Lausanne). 2022;13:834674. 10.3389/fendo.2022.834674
- Leventogiannis K, Gkolfakis P, Spithakis G, Tsatali A, Pistiki A, et al. Effect of a Preparation of Four Probiotics on Symptoms of Patients with Irritable Bowel Syndrome: Association with Intestinal Bacterial Overgrowth. Probiotics Antimicrob Proteins. 2019;11:627. 10.1007/s12602-018-9401-3
- Kim BK, Choi IS, Kim J, Han SH, Suh HJ, et al. Effects of Fermented Milk with Mixed Strains as a Probiotic on the Inhibition of Loperamide-Induced Constipation. Korean J Food Sci Anim Resour. 2017;37:906. 10.5851/kosfa.2017.37.6.906
- Choi SC, Kim BJ, Rhee PL, Chang DK, Son HJ, et al. Probiotic Fermented Milk Containing Dietary Fiber Has Additive Effects in IBS with Constipation Compared to Plain Probiotic Fermented Milk. Gut Liver. 2011;5:22. 10.5009/gnl.2011.5.1.22
- Nova E, Viadel B, Wärnberg J, Carreres JE, Marcos A. Beneficial effects of a synbiotic supplement on self-perceived gastrointestinal well-being and immunoinflammatory status of healthy adults. J Med Food. 2011;14:79. 10.1089/jmf.2008.0328
- Zhu S, Guo Z, Liu L, Gao Y, Bai L, et al. Complex Probiotics Relieve Constipation Through Regulation of the Intestinal Microbiota in Kittens. Microorganisms. 2025;13. 10.3390/microorganisms13030563
- Zhang Z, Li J, Wan Z, Fang S, Zhao Y, et al. subsp. BLa80 alleviates constipation in mice through modulating the stem cell factor (SCF)/c-Kit pathway and the gut microbiota. Food Funct. 2025;16:2347. 10.1039/d4fo06350c
- Ma W, Zhao Y, Liu Y, Wang Y, Yu S, et al. subsp. TG11 ameliorates loperamide-induced constipation in mice by modulating gut microbiota. Front Microbiol. 2025;16:1525887. 10.3389/fmicb.2025.1525887
- Zhang C, Wang L, Liu X, Wang G, Zhao J, et al. subsp. relieves loperamide hydrochloride-induced constipation in mice by enhancing bile acid dissociation. Food Funct. 2025;16:297. 10.1039/d4fo04660a
- Salo E, Roche D, Gomez-Martinez VB, Cruz-Domenech JM, Garcia-Mora LG, et al. Bifidobacterium animalis subsp. lactis BLa80 regulates the intestinal habit in adults with chronic constipation: a multicentre, randomised, double-blind, placebo-controlled study. Benef Microbes. 2024;15:679. 10.1163/18762891-bja00038
- Lan W, Yang H, Zhong Z, Luo C, Huang Q, et al. subsp. LPL-RH improves postoperative gastrointestinal symptoms and nutrition indexes by regulating the gut microbiota in patients with valvular heart disease: a randomized controlled trial. Food Funct. 2024;15:7605. 10.1039/d4fo01471e
- JanssenDuijghuijsen L, van den Belt M, Rijnaarts I, Vos P, Guillemet D, et al. Acacia fiber or probiotic supplements to relieve gastrointestinal complaints in patients with constipation-predominant IBS: a 4-week randomized double-blinded placebo-controlled intervention trial. Eur J Nutr. 2024;63:1983. 10.1007/s00394-024-03398-8
- Chen K, Zhou Z, Nie Y, Cao Y, Yang P, et al. Adjunctive efficacy of Bifidobacterium animalis subsp. lactis XLTG11 for functional constipation in children. Braz J Microbiol. 2024;55:1317. 10.1007/s42770-024-01276-3
- Lu Y, Zhou X, Wu Y, Cui Q, Tian X, et al. Metabolites 13,14-Dihydro-15-keto-PGE2 Participates in Bifidobacterium animalis F1-7 to Alleviate Opioid-Induced Constipation by 5-HT Pathway. Mol Nutr Food Res. 2024;68:e2200846. 10.1002/mnfr.202200846
- Skrzydło-Radomańska B, Prozorow-Król B, Kurzeja-Mirosław A, Cichoż-Lach H, Laskowska K, et al. The Efficacy and Safety of Single-Strain Probiotic Formulations Containing or in Adult Patients with Irritable Bowel Syndrome-A Randomized Double-Blind Placebo-Controlled Three-Arm Interventional Trial. J Clin Med. 2023;12. 10.3390/jcm12144838
- Watanabe M, Maruo T, Suzuki T. Effects of intake of subsp. FC on constipation symptoms and immune system in healthy participants with mild constipation: a double-blind, placebo-controlled study. Int J Food Sci Nutr. 2023;74:695. 10.1080/09637486.2023.2236805
- Jeong JJ, Ganesan R, Jin YJ, Park HJ, Min BH, et al. Multi-strain probiotics alleviate loperamide-induced constipation by adjusting the microbiome, serotonin, and short-chain fatty acids in rats. Front Microbiol. 2023;14:1174968. 10.3389/fmicb.2023.1174968
- Lai H, Li Y, He Y, Chen F, Mi B, et al. Effects of dietary fibers or probiotics on functional constipation symptoms and roles of gut microbiota: a double-blinded randomized placebo trial. Gut Microbes. 2023;15:2197837. 10.1080/19490976.2023.2197837
- Cui H, Wang Q, Feng C, Guo C, Zhang J, et al. Positive effect of subsp VHProbi YB11 in improving gastrointestinal movement of mice having constipation. Front Microbiol. 2022;13:1040371. 10.3389/fmicb.2022.1040371
- van der Schoot A, Helander C, Whelan K, Dimidi E. Probiotics and synbiotics in chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials. Clin Nutr. 2022;41:2759. 10.1016/j.clnu.2022.10.015
- Noda M, Danshiitsoodol N, Kanno K, Sugiyama M. Silk-derived sericin/fibroin mixture drink fermented with plant-derived BM32-1 improves constipation and related microbiota: a randomized, double-blind, and placebo-controlled clinical trial. Biosci Microbiota Food Health. 2024;43:282. 10.12938/bmfh.2023-102
- Tan Q, Hu J, Zhou Y, Wan Y, Zhang C, et al. Inhibitory Effect of subsp. HFY14 on Diphenoxylate-Induced Constipation in Mice by Regulating the VIP-cAMP-PKA-AQP3 Signaling Pathway. Drug Des Devel Ther. 2021;15:1971. 10.2147/DDDT.S309675
- Gotoh Y, Nanba F, Shioya N, Sugimura H, Suzuki T. A dose-finding study for a supplement containing subsp. FC in healthy adults with mild constipation. Biosci Microbiota Food Health. 2020;39:19. 10.12938/bmfh.19-009
- Ozaki K, Maruo T, Kosaka H, Mori M, Mori H, et al. The effects of fermented milk containing Lactococcus lactis subsp. cremoris FC on defaecation in healthy young Japanese women: a double-blind, placebo-controlled study. Int J Food Sci Nutr. 2018;69:762. 10.1080/09637486.2017.1417977
- Higashikawa F, Noda M, Awaya T, Nomura K, Oku H, et al. Improvement of constipation and liver function by plant-derived lactic acid bacteria: a double-blind, randomized trial. Nutrition. 2010;26:367. 10.1016/j.nut.2009.05.008
