Medical Researches
Possibly Effective
Based on 32 Researches
We investigated the effects of Lactobacillus rhamnosus (LRJ-1) on constipation in mice. The study revealed that oral treatment with LRJ-1 led to significant improvements in constipation by increasing levels of a gut compound called γ-aminobutyric acid (GABA).
We also found that the beneficial impact of LRJ-1 was linked to the growth of specific intestinal bacteria and the activation of certain nerve pathways in the gut. While these findings are promising, they confirm the potential of LRJ-1 in addressing constipation through its influence on gut health.
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Probiotic improves IBS-C symptomsEffect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial.
High relevance for constipation treatment
We examined the effects of Lacticaseibacillus rhamnosus IDCC 3201 on patients suffering from irritable bowel syndrome with constipation (IBS-C). In a robust study involving 30 participants, we used a randomized, double-blind, placebo-controlled design.
After eight weeks of treatment, the probiotic group reported significant improvements in bowel activities and discomfort linked to constipation. Notably, symptoms like abdominal bloating also improved.
Our findings suggest that this probiotic might help enhance gut health by promoting beneficial microbes and their metabolites.
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We examined the effects of Lacticaseibacillus rhamnosus VHProbi®M15 on constipation caused by sucralfate in mice. In a controlled study, groups of mice were either untreated, constipated, or given treatments with M15 or a standard laxative.
Our findings showed that M15 improved fecal water content and intestinal movement compared to untreated mice. Additionally, it helped restore gut health and boosted certain neurotransmitters related to digestion. Overall, M15 showed promise in alleviating constipation symptoms in this mouse model.
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We investigated the impact of environmental pollutants on gut motility and whether Lactobacillus rhamnosus GG (LGG) could help restore normal function.
Exposed to pollutants, zebrafish showed reduced intestinal movement alongside decreased serotonin levels.
However, when treated with LGG, the zebrafish exhibited a significant improvement in gut motility through enhanced serotonin secretion.
This suggests that LGG may offer a probiotic solution to gut dysmotility caused by pollutants by rebuilding serotonin levels.
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Synbiotics effective for child constipationInvestigation of the efficacy of synbiotics in the treatment of functional constipation in children: a randomized double-blind placebo-controlled study.
Strong relevance, significant findings
We examined whether synbiotics, which include Lactobacillus rhamnosus and other beneficial bacteria, help relieve functional constipation in children aged 4 to 18. In a controlled study, one group received synbiotics while the other received a placebo for four weeks.
At the end of the treatment, we saw a significant improvement in defecation frequency and abdominal pain in the synbiotic group compared to the placebo group. In fact, two-thirds of children using synbiotics reported complete relief, highlighting their effectiveness.
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User Reviews
Good for babies. My baby is thriving without constipation or colic.
Wonderful, my child had constipation but after three days of use, her bowel movements returned to normal. Alhamdulillah.
An excellent probiotic for babies. We used it for a year in mixtures or porridge. It helped eliminate constipation and normalised her stools.
An incredible remedy; it helped tremendously with colic and stopped my baby’s constipation. I highly recommend it.
Restored intestinal health
These probiotics are highly effective for my baby’s constipation and restoring microflora, plus it contains Vitamin D, which is crucial for growth.