'
SCIENTIFIC SCORE
Possibly Effective
Based on 32 Researches
7.8
USERS' SCORE
Good
Based on 22 Reviews
8.2
Supplement Facts
Serving Size: Five (5) Drops
Amount Per Serving
%DV
Calories
0
 
Total Carbohydrate
0 g
0%
Total Sugars
0 g
**
Incl. 0 g Added Sugars
 
**
Vitamin D (as cholecalciferol)
10 mcg (400 IU)
100%
Probiotic Blend
29 mg (2.5 billion CFUs)
 
Lactobacillus rhamnosus GG
 
**
Bifidobacterium animalis subsp. lactis (BB-12®)
 
**

Top Medical Research Studies

9
Probiotic improves IBS-C symptoms
Effect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial.
High relevance for constipation treatment
We examined the effects of Lacticaseibacillus rhamnosus IDCC 3201 on patients suffering from irritable bowel syndrome with constipation (IBS-C). In a robust study involving 30 participants, we used a randomized, double-blind, placebo-controlled design.

After eight weeks of treatment, the probiotic group reported significant improvements in bowel activities and discomfort linked to constipation. Notably, symptoms like abdominal bloating also improved.

Our findings suggest that this probiotic might help enhance gut health by promoting beneficial microbes and their metabolites.
Read More
9
BLa80 shows promise for constipation
subsp. BLa80 alleviates constipation in mice through modulating the stem cell factor (SCF)/c-Kit pathway and the gut microbiota.
Relevance score indicates high potential
We explored the impact of Bifidobacterium lactis BLa80 on constipation using mice that were induced with functional constipation through loperamide treatment. In our study, we compared BLa80 to a blank group and a positive control.

The results indicated that BLa80 improved intestinal movement, increased fecal moisture, and balanced gut bacteria. It also helped regulate important gut hormones. Overall, BLa80 shows promise as a potential new option for relieving constipation in functional foods.
Read More
9
Bifidobacterium lactis alleviates constipation
subsp. TG11 ameliorates loperamide-induced constipation in mice by modulating gut microbiota.
Relevant animal model study
We investigated the effects of Bifidobacterium lactis subsp. TG11 on loperamide-induced constipation in mice. The mice were grouped into control and treatment categories, receiving different doses of the probiotic.

After treatment, those receiving TG11 showed improved intestinal motility and maintained better fecal water content. Notably, the probiotic also positively affected gut microbiota, increasing beneficial bacteria and promoting short-chain fatty acid production.

Overall, Bifidobacterium lactis TG11 appears effective in alleviating constipation, potentially by enhancing gut health.
Read More

Most Useful Reviews

9
Cut back Miralax
A blessing for my daughter's tummy issues. My daughter experienced constipation since switching to formula at three months. Her nutritionist suggested these probiotics, which have been tremendously helpful. At 14 months, we have significantly reduced her Miralax usage, and since starting the probiotics, we haven’t had any ER visits for impacted stools. For babies with gastrointestinal problems, consider discussing this product with your child's paediatrician or nutritionist.
Read More
9.5
Eliminated constipation
Good for babies. My baby is thriving without constipation or colic.
Read More
9.5
Regulated stools
Wonderful, my child had constipation but after three days of use, her bowel movements returned to normal. Alhamdulillah.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 32 Researches
7.8
9
Lactobacillus rhamnosus reduces constipation
LRJ-1 alleviates constipation through promoting gut -derived γ-aminobutyric acid production.
Study highlights gut therapy relevance.
We investigated the effects of Lactobacillus rhamnosus (LRJ-1) on constipation in mice. The study revealed that oral treatment with LRJ-1 led to significant improvements in constipation by increasing levels of a gut compound called γ-aminobutyric acid (GABA).

We also found that the beneficial impact of LRJ-1 was linked to the growth of specific intestinal bacteria and the activation of certain nerve pathways in the gut. While these findings are promising, they confirm the potential of LRJ-1 in addressing constipation through its influence on gut health.
Read More
9
Probiotic improves IBS-C symptoms
Effect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial.
High relevance for constipation treatment
We examined the effects of Lacticaseibacillus rhamnosus IDCC 3201 on patients suffering from irritable bowel syndrome with constipation (IBS-C). In a robust study involving 30 participants, we used a randomized, double-blind, placebo-controlled design.

After eight weeks of treatment, the probiotic group reported significant improvements in bowel activities and discomfort linked to constipation. Notably, symptoms like abdominal bloating also improved.

Our findings suggest that this probiotic might help enhance gut health by promoting beneficial microbes and their metabolites.
Read More
9
M15 alleviates sucralfate-induced constipation
Probiotic potential of Lacticaseibacillus rhamnosus VHProbi M15 on sucralfate-induced constipation in mice.
Study relevance: Moderate
We examined the effects of Lacticaseibacillus rhamnosus VHProbi®M15 on constipation caused by sucralfate in mice. In a controlled study, groups of mice were either untreated, constipated, or given treatments with M15 or a standard laxative.

Our findings showed that M15 improved fecal water content and intestinal movement compared to untreated mice. Additionally, it helped restore gut health and boosted certain neurotransmitters related to digestion. Overall, M15 showed promise in alleviating constipation symptoms in this mouse model.
Read More
9
Lactobacillus rhamnosus restores gut motility
Lactobacillus rhamnosus GG normalizes gut dysmotility induced by environmental pollutants via affecting serotonin level in zebrafish larvae.
Relevant findings on gut health
We investigated the impact of environmental pollutants on gut motility and whether Lactobacillus rhamnosus GG (LGG) could help restore normal function.

Exposed to pollutants, zebrafish showed reduced intestinal movement alongside decreased serotonin levels.

However, when treated with LGG, the zebrafish exhibited a significant improvement in gut motility through enhanced serotonin secretion.

This suggests that LGG may offer a probiotic solution to gut dysmotility caused by pollutants by rebuilding serotonin levels.
Read More
9
Synbiotics effective for child constipation
Investigation of the efficacy of synbiotics in the treatment of functional constipation in children: a randomized double-blind placebo-controlled study.
Strong relevance, significant findings
We examined whether synbiotics, which include Lactobacillus rhamnosus and other beneficial bacteria, help relieve functional constipation in children aged 4 to 18. In a controlled study, one group received synbiotics while the other received a placebo for four weeks.

At the end of the treatment, we saw a significant improvement in defecation frequency and abdominal pain in the synbiotic group compared to the placebo group. In fact, two-thirds of children using synbiotics reported complete relief, highlighting their effectiveness.
Read More

User Reviews

USERS' SCORE
Good
Based on 22 Reviews
8.2
9.5
Eliminated constipation
Good for babies. My baby is thriving without constipation or colic.
9.5
Regulated stools
Wonderful, my child had constipation but after three days of use, her bowel movements returned to normal. Alhamdulillah.
9.5
Solved constipation
An excellent probiotic for babies. We used it for a year in mixtures or porridge. It helped eliminate constipation and normalised her stools.
9.5
Miracle remedy
An incredible remedy; it helped tremendously with colic and stopped my baby’s constipation. I highly recommend it.
9.5
Restored intestinal health
These probiotics are highly effective for my baby’s constipation and restoring microflora, plus it contains Vitamin D, which is crucial for growth.
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