' 
![]()
SCIENTIFIC SCORE
Possibly Effective
Based on 54 Researches
7.6
USERS' SCORE
Good
Based on 215 Reviews
8
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Proprietary Probiotic BlendLacticaseibacillus rhamnosus R0011Lactobacillus helvetius R0052Pediococcus acidilactici R1001Lacticaseibacillus casei R0215Bifidobacterium longum BB536Lactiplantibacillus plantarum R1012Bifidobacterium breve R0070Lactococcus lactis subsp. lactis R1058
131 mg (10 Billion CFU)
†
Top Medical Research Studies
9
Probiotic improves IBS-C symptoms
Effect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial.
High relevance for constipation treatment
We examined the effects of Lacticaseibacillus rhamnosus IDCC 3201 on patients suffering from irritable bowel syndrome with constipation (IBS-C). In a robust study involving 30 participants, we used a randomized, double-blind, placebo-controlled design.
After eight weeks of treatment, the probiotic group reported significant improvements in bowel activities and discomfort linked to constipation. Notably, symptoms like abdominal bloating also improved.
Our findings suggest that this probiotic might help enhance gut health by promoting beneficial microbes and their metabolites.
After eight weeks of treatment, the probiotic group reported significant improvements in bowel activities and discomfort linked to constipation. Notably, symptoms like abdominal bloating also improved.
Our findings suggest that this probiotic might help enhance gut health by promoting beneficial microbes and their metabolites.
Read More
9
BLa80 shows promise for constipation
subsp. BLa80 alleviates constipation in mice through modulating the stem cell factor (SCF)/c-Kit pathway and the gut microbiota.
Relevance score indicates high potential
We explored the impact of Bifidobacterium lactis BLa80 on constipation using mice that were induced with functional constipation through loperamide treatment. In our study, we compared BLa80 to a blank group and a positive control.
The results indicated that BLa80 improved intestinal movement, increased fecal moisture, and balanced gut bacteria. It also helped regulate important gut hormones. Overall, BLa80 shows promise as a potential new option for relieving constipation in functional foods.
The results indicated that BLa80 improved intestinal movement, increased fecal moisture, and balanced gut bacteria. It also helped regulate important gut hormones. Overall, BLa80 shows promise as a potential new option for relieving constipation in functional foods.
Read More
9
Bifidobacterium lactis alleviates constipation
subsp. TG11 ameliorates loperamide-induced constipation in mice by modulating gut microbiota.
Relevant animal model study
We investigated the effects of Bifidobacterium lactis subsp. TG11 on loperamide-induced constipation in mice. The mice were grouped into control and treatment categories, receiving different doses of the probiotic.
After treatment, those receiving TG11 showed improved intestinal motility and maintained better fecal water content. Notably, the probiotic also positively affected gut microbiota, increasing beneficial bacteria and promoting short-chain fatty acid production.
Overall, Bifidobacterium lactis TG11 appears effective in alleviating constipation, potentially by enhancing gut health.
After treatment, those receiving TG11 showed improved intestinal motility and maintained better fecal water content. Notably, the probiotic also positively affected gut microbiota, increasing beneficial bacteria and promoting short-chain fatty acid production.
Overall, Bifidobacterium lactis TG11 appears effective in alleviating constipation, potentially by enhancing gut health.
Read More
Most Useful Reviews
9.5
Best for constipation
I take these every morning on an empty stomach and am very pleased with the results. Bloating has decreased, and my digestion has improved, allowing for regular visits to the restroom. When I stop, constipation returns. After trying various probiotics, I find this one to be the best quality.
Read More
9.5
Beneficial probiotics
These probiotics are trustworthy and help maintain intestinal flora. They enhance digestion, combat flatulence, and promote regularity, making them ideal for preventive care. I appreciate the well-sealed capsules that dissolve effectively in the intestines.
Read More
9.5
Child's improvement
This is the most effective probiotic I have tried. After giving it to my child, who suffered from constipation, they now go to the toilet easily every day. I highly recommend it.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 54 Researches
7.6
9
Lactobacillus rhamnosus reduces constipation
LRJ-1 alleviates constipation through promoting gut -derived γ-aminobutyric acid production.
Study highlights gut therapy relevance.
We investigated the effects of Lactobacillus rhamnosus (LRJ-1) on constipation in mice. The study revealed that oral treatment with LRJ-1 led to significant improvements in constipation by increasing levels of a gut compound called γ-aminobutyric acid (GABA).
We also found that the beneficial impact of LRJ-1 was linked to the growth of specific intestinal bacteria and the activation of certain nerve pathways in the gut. While these findings are promising, they confirm the potential of LRJ-1 in addressing constipation through its influence on gut health.
We also found that the beneficial impact of LRJ-1 was linked to the growth of specific intestinal bacteria and the activation of certain nerve pathways in the gut. While these findings are promising, they confirm the potential of LRJ-1 in addressing constipation through its influence on gut health.
Read More
9
Probiotic improves IBS-C symptoms
Effect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial.
High relevance for constipation treatment
We examined the effects of Lacticaseibacillus rhamnosus IDCC 3201 on patients suffering from irritable bowel syndrome with constipation (IBS-C). In a robust study involving 30 participants, we used a randomized, double-blind, placebo-controlled design.
After eight weeks of treatment, the probiotic group reported significant improvements in bowel activities and discomfort linked to constipation. Notably, symptoms like abdominal bloating also improved.
Our findings suggest that this probiotic might help enhance gut health by promoting beneficial microbes and their metabolites.
After eight weeks of treatment, the probiotic group reported significant improvements in bowel activities and discomfort linked to constipation. Notably, symptoms like abdominal bloating also improved.
Our findings suggest that this probiotic might help enhance gut health by promoting beneficial microbes and their metabolites.
Read More
9
M15 alleviates sucralfate-induced constipation
Probiotic potential of Lacticaseibacillus rhamnosus VHProbi M15 on sucralfate-induced constipation in mice.
Study relevance: Moderate
We examined the effects of Lacticaseibacillus rhamnosus VHProbi®M15 on constipation caused by sucralfate in mice. In a controlled study, groups of mice were either untreated, constipated, or given treatments with M15 or a standard laxative.
Our findings showed that M15 improved fecal water content and intestinal movement compared to untreated mice. Additionally, it helped restore gut health and boosted certain neurotransmitters related to digestion. Overall, M15 showed promise in alleviating constipation symptoms in this mouse model.
Our findings showed that M15 improved fecal water content and intestinal movement compared to untreated mice. Additionally, it helped restore gut health and boosted certain neurotransmitters related to digestion. Overall, M15 showed promise in alleviating constipation symptoms in this mouse model.
Read More
9
Lactobacillus rhamnosus restores gut motility
Lactobacillus rhamnosus GG normalizes gut dysmotility induced by environmental pollutants via affecting serotonin level in zebrafish larvae.
Relevant findings on gut health
We investigated the impact of environmental pollutants on gut motility and whether Lactobacillus rhamnosus GG (LGG) could help restore normal function.
Exposed to pollutants, zebrafish showed reduced intestinal movement alongside decreased serotonin levels.
However, when treated with LGG, the zebrafish exhibited a significant improvement in gut motility through enhanced serotonin secretion.
This suggests that LGG may offer a probiotic solution to gut dysmotility caused by pollutants by rebuilding serotonin levels.
Exposed to pollutants, zebrafish showed reduced intestinal movement alongside decreased serotonin levels.
However, when treated with LGG, the zebrafish exhibited a significant improvement in gut motility through enhanced serotonin secretion.
This suggests that LGG may offer a probiotic solution to gut dysmotility caused by pollutants by rebuilding serotonin levels.
Read More
9
Synbiotics effective for child constipation
Investigation of the efficacy of synbiotics in the treatment of functional constipation in children: a randomized double-blind placebo-controlled study.
Strong relevance, significant findings
We examined whether synbiotics, which include Lactobacillus rhamnosus and other beneficial bacteria, help relieve functional constipation in children aged 4 to 18. In a controlled study, one group received synbiotics while the other received a placebo for four weeks.
At the end of the treatment, we saw a significant improvement in defecation frequency and abdominal pain in the synbiotic group compared to the placebo group. In fact, two-thirds of children using synbiotics reported complete relief, highlighting their effectiveness.
At the end of the treatment, we saw a significant improvement in defecation frequency and abdominal pain in the synbiotic group compared to the placebo group. In fact, two-thirds of children using synbiotics reported complete relief, highlighting their effectiveness.
Read More
User Reviews
USERS' SCORE
Good
Based on 215 Reviews
8
10
Effective for constipation
Since I started taking this product on an empty stomach, I've noticed a significant improvement in my terrible constipation. Farting has also increased, but my stools are much better now. I wish to continue this forever.
10
Restored bowel routine
After switching to this supplement, I was able to go to the restroom comfortably and consistently after just four days. Now, I take one capsule each morning and no longer struggle with constipation.
10
Daily bowel movements
Initially, I thought I was just less regular, but this product made me realise I'd been living with constipation my entire life. I now have regular bowel movements almost every day, and my digestion and skin appear to be improving as well.
10
Maintains regularity
This is my favourite supplement that I take daily. It keeps my intestines healthy, and I never experience constipation while using it.
10
Constipation resolved
My constipation was cured! It worked effectively when nothing else did!
