5/10/2025
Last update
5/10/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 59 Researches
7.5
USERS' SCORE
Good
Based on 15 Reviews
8.4
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Women's Care Probiotic Blend
50 Billion CFU 222 mg
***
Bifido Probiotic BlendBifidobacterium lactis BI-04®, Bifidobacterium lactis DSM 15954, Bifidobacterium infantis Bi-26™
26 Billion CFU
Lacto Probiotic BlendLactobacillus reuteri RC-14®, Lactobacillus plantarum Lp-115®, Lactobacillus rhamnosus GG, Lactobacillus rhamnosus GR-1®, Lactococcus lactis LI-23™, Lactobacillus casei Lc-11®, Lactobacillus paracasei Lpc-37®, Lactobacillus acidophilus La-14®, Lactobacillus brevis Lbr-35™
24 Billion CFU
Top Medical Research Studies
9
We explored the impact of Bifidobacterium lactis BLa80 on constipation using mice that were induced with functional constipation through loperamide treatment. In our study, we compared BLa80 to a blank group and a positive control.
The results indicated that BLa80 improved intestinal movement, increased fecal moisture, and balanced gut bacteria. It also helped regulate important gut hormones. Overall, BLa80 shows promise as a potential new option for relieving constipation in functional foods.
The results indicated that BLa80 improved intestinal movement, increased fecal moisture, and balanced gut bacteria. It also helped regulate important gut hormones. Overall, BLa80 shows promise as a potential new option for relieving constipation in functional foods.
Read More
9
We investigated the effects of Bifidobacterium lactis subsp. TG11 on loperamide-induced constipation in mice. The mice were grouped into control and treatment categories, receiving different doses of the probiotic.
After treatment, those receiving TG11 showed improved intestinal motility and maintained better fecal water content. Notably, the probiotic also positively affected gut microbiota, increasing beneficial bacteria and promoting short-chain fatty acid production.
Overall, Bifidobacterium lactis TG11 appears effective in alleviating constipation, potentially by enhancing gut health.
After treatment, those receiving TG11 showed improved intestinal motility and maintained better fecal water content. Notably, the probiotic also positively affected gut microbiota, increasing beneficial bacteria and promoting short-chain fatty acid production.
Overall, Bifidobacterium lactis TG11 appears effective in alleviating constipation, potentially by enhancing gut health.
Read More
9
We assessed the effectiveness of Bifidobacterium animalis subsp. lactis XLTG11 in helping children with functional constipation through a well-structured study with a randomized, double-blinded, placebo-controlled design. The children were split into two groups: one received the probiotic treatment alongside conventional care, while the other did not.
Over the treatment period, we saw a consistent increase in bowel movements in the group taking the probiotic, showing higher fecal frequency compared to the control group. Additionally, the beneficial bacteria in their guts improved, which suggests that this treatment is a promising approach for managing constipation in children.
Over the treatment period, we saw a consistent increase in bowel movements in the group taking the probiotic, showing higher fecal frequency compared to the control group. Additionally, the beneficial bacteria in their guts improved, which suggests that this treatment is a promising approach for managing constipation in children.
Read More
Most Useful Reviews
10
Improved digestion
7 people found this helpful
I felt much better after using this probiotic. At 45 years old and suffering from constipation, I struggled to find the right one. After trying four different types, Ultimate Flora worked brilliantly; I had regular bowel movements every day. I highly recommend it.
Read More
9
Reduced bloating
3 people found this helpful
Recommended by my gynecologist for recurring infections, I've noticed improved digestion and less bloating. On days I take the recommended amount, I feel comfortable and free of constipation. The taste is sweet and comes in small, thick capsules.
Read More
10
Effective for UTIs
1 people found this helpful
This is the only brand that has genuinely helped with my UTI and didn't cause constipation. Though it's a bit pricey, it’s worth it to avoid doctor visits. Fast absorption and beneficial for gut health. I've just ordered two more bottles.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 59 Researches
7.5
- All Researches
9.5
Lactobacillus improves IBS-C symptoms
We investigated how a cultured milk drink containing Lactobacillus acidophilus affects symptoms of constipation in individuals with irritable bowel syndrome (IBS-C). Over 30 days, participants consumed the drink daily.
At the end of the study, an impressive 97.4% of IBS-C participants reported improvement in their constipation-related symptoms. We also noticed reductions in intestinal transit time and pro-inflammatory cytokines linked to IBS. Overall, this suggests that including this cultured milk drink may be a beneficial addition to IBS-C treatment plans.
At the end of the study, an impressive 97.4% of IBS-C participants reported improvement in their constipation-related symptoms. We also noticed reductions in intestinal transit time and pro-inflammatory cytokines linked to IBS. Overall, this suggests that including this cultured milk drink may be a beneficial addition to IBS-C treatment plans.
Read More
9
We explored the impact of Bifidobacterium lactis BLa80 on constipation using mice that were induced with functional constipation through loperamide treatment. In our study, we compared BLa80 to a blank group and a positive control.
The results indicated that BLa80 improved intestinal movement, increased fecal moisture, and balanced gut bacteria. It also helped regulate important gut hormones. Overall, BLa80 shows promise as a potential new option for relieving constipation in functional foods.
The results indicated that BLa80 improved intestinal movement, increased fecal moisture, and balanced gut bacteria. It also helped regulate important gut hormones. Overall, BLa80 shows promise as a potential new option for relieving constipation in functional foods.
Read More
9
We investigated the effects of Bifidobacterium lactis subsp. TG11 on loperamide-induced constipation in mice. The mice were grouped into control and treatment categories, receiving different doses of the probiotic.
After treatment, those receiving TG11 showed improved intestinal motility and maintained better fecal water content. Notably, the probiotic also positively affected gut microbiota, increasing beneficial bacteria and promoting short-chain fatty acid production.
Overall, Bifidobacterium lactis TG11 appears effective in alleviating constipation, potentially by enhancing gut health.
After treatment, those receiving TG11 showed improved intestinal motility and maintained better fecal water content. Notably, the probiotic also positively affected gut microbiota, increasing beneficial bacteria and promoting short-chain fatty acid production.
Overall, Bifidobacterium lactis TG11 appears effective in alleviating constipation, potentially by enhancing gut health.
Read More
9
Bifidobacterium lactis effective for constipation
We assessed how Bifidobacterium animalis subsp. lactis BLa80 could help adults struggling with chronic constipation. In a multicentre, randomised, double-blind, placebo-controlled trial involving 46 participants, we compared the effects of the probiotic against a placebo over 12 weeks.
Our findings revealed that those taking the probiotic experienced a significant improvement in stool consistency and a reduction in constipation symptoms. By weeks 8 and 12, their stool types shifted towards more normal classifications on the Bristol scale, while constipation rates increased in the placebo group.
This highlights the potential of Bifidobacterium lactis as a helpful solution for managing constipation.
Our findings revealed that those taking the probiotic experienced a significant improvement in stool consistency and a reduction in constipation symptoms. By weeks 8 and 12, their stool types shifted towards more normal classifications on the Bristol scale, while constipation rates increased in the placebo group.
This highlights the potential of Bifidobacterium lactis as a helpful solution for managing constipation.
Read More
9
We assessed the effectiveness of Bifidobacterium animalis subsp. lactis XLTG11 in helping children with functional constipation through a well-structured study with a randomized, double-blinded, placebo-controlled design. The children were split into two groups: one received the probiotic treatment alongside conventional care, while the other did not.
Over the treatment period, we saw a consistent increase in bowel movements in the group taking the probiotic, showing higher fecal frequency compared to the control group. Additionally, the beneficial bacteria in their guts improved, which suggests that this treatment is a promising approach for managing constipation in children.
Over the treatment period, we saw a consistent increase in bowel movements in the group taking the probiotic, showing higher fecal frequency compared to the control group. Additionally, the beneficial bacteria in their guts improved, which suggests that this treatment is a promising approach for managing constipation in children.
Read More
User Reviews
USERS' SCORE
Good
Based on 15 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
10
Improved digestion
7 people found this helpful
I felt much better after using this probiotic. At 45 years old and suffering from constipation, I struggled to find the right one. After trying four different types, Ultimate Flora worked brilliantly; I had regular bowel movements every day. I highly recommend it.
Read More
9
Reduced bloating
3 people found this helpful
Recommended by my gynecologist for recurring infections, I've noticed improved digestion and less bloating. On days I take the recommended amount, I feel comfortable and free of constipation. The taste is sweet and comes in small, thick capsules.
Read More
10
Effective for UTIs
1 people found this helpful
This is the only brand that has genuinely helped with my UTI and didn't cause constipation. Though it's a bit pricey, it’s worth it to avoid doctor visits. Fast absorption and beneficial for gut health. I've just ordered two more bottles.
Read More
10
Better digestion
1 people found this helpful
Excellent! After trying many probiotic brands for digestion and constipation, I saw the reviews for this product and decided to try it. After two bottles, I feel much better regarding my yeast infection. I’m ordering it for the third time from iHerb. Highly recommended!
Read More
10
Improved digestion
1 people found this helpful
Excellent quality and concentrated supplement with a pleasant taste. I felt the effects immediately, with improved digestion and resolved constipation issues. I’m very pleased!
Read More
Frequently Asked Questions
10
Improved digestion
7 people found this helpful
I felt much better after using this probiotic. At 45 years old and suffering from constipation, I struggled to find the right one. After trying four different types, Ultimate Flora worked brilliantly; I had regular bowel movements every day. I highly recommend it.
7.5
Improved bowel movements
1 people found this helpful
Occasionally, I feel tired and have developed bacterial vaginosis along with cystitis. Despite this, my bowel movements have greatly improved since I started taking this supplement. I used to suffer from constipation, having only three bowel movements a week, but now I experience them almost daily. I hope it will also be effective for vaginitis, my primary concern.
10
Improved digestion
1 people found this helpful
Excellent quality and concentrated supplement with a pleasant taste. I felt the effects immediately, with improved digestion and resolved constipation issues. I’m very pleased!
9
Mood improvement
This product has helped my constipation linked to stress, improving both my digestive health and mood. Although it's expensive, the high-quality lactic acid bacteria make it worth the cost!
2
Ineffective for constipation
Unfortunately, this supplement did not work for my constipation, leading me to stop taking it before I could gauge its quality for improving the microbiome.
9
Reduced bloating
3 people found this helpful
Recommended by my gynecologist for recurring infections, I've noticed improved digestion and less bloating. On days I take the recommended amount, I feel comfortable and free of constipation. The taste is sweet and comes in small, thick capsules.
10
Better digestion
1 people found this helpful
Excellent! After trying many probiotic brands for digestion and constipation, I saw the reviews for this product and decided to try it. After two bottles, I feel much better regarding my yeast infection. I’m ordering it for the third time from iHerb. Highly recommended!
9
Good for gut health
The high-quality lactic acid bacteria are beneficial for women, aiding digestion and combatting constipation effectively. The absorption rate is impressive and supports intestine health.
9
Bifidobacterium lactis effective for constipation
We assessed how Bifidobacterium animalis subsp. lactis BLa80 could help adults struggling with chronic constipation. In a multicentre, randomised, double-blind, placebo-controlled trial involving 46 participants, we compared the effects of the probiotic against a placebo over 12 weeks.
Our findings revealed that those taking the probiotic experienced a significant improvement in stool consistency and a reduction in constipation symptoms. By weeks 8 and 12, their stool types shifted towards more normal classifications on the Bristol scale, while constipation rates increased in the placebo group.
This highlights the potential of Bifidobacterium lactis as a helpful solution for managing constipation.
Our findings revealed that those taking the probiotic experienced a significant improvement in stool consistency and a reduction in constipation symptoms. By weeks 8 and 12, their stool types shifted towards more normal classifications on the Bristol scale, while constipation rates increased in the placebo group.
This highlights the potential of Bifidobacterium lactis as a helpful solution for managing constipation.
9
We assessed the effectiveness of Bifidobacterium animalis subsp. lactis XLTG11 in helping children with functional constipation through a well-structured study with a randomized, double-blinded, placebo-controlled design. The children were split into two groups: one received the probiotic treatment alongside conventional care, while the other did not.
Over the treatment period, we saw a consistent increase in bowel movements in the group taking the probiotic, showing higher fecal frequency compared to the control group. Additionally, the beneficial bacteria in their guts improved, which suggests that this treatment is a promising approach for managing constipation in children.
Over the treatment period, we saw a consistent increase in bowel movements in the group taking the probiotic, showing higher fecal frequency compared to the control group. Additionally, the beneficial bacteria in their guts improved, which suggests that this treatment is a promising approach for managing constipation in children.
9
We explored the impact of Bifidobacterium lactis BLa80 on constipation using mice that were induced with functional constipation through loperamide treatment. In our study, we compared BLa80 to a blank group and a positive control.
The results indicated that BLa80 improved intestinal movement, increased fecal moisture, and balanced gut bacteria. It also helped regulate important gut hormones. Overall, BLa80 shows promise as a potential new option for relieving constipation in functional foods.
The results indicated that BLa80 improved intestinal movement, increased fecal moisture, and balanced gut bacteria. It also helped regulate important gut hormones. Overall, BLa80 shows promise as a potential new option for relieving constipation in functional foods.
References
- Zhu S, Guo Z, Liu L, Gao Y, Bai L, et al. Complex Probiotics Relieve Constipation Through Regulation of the Intestinal Microbiota in Kittens. Microorganisms. 2025;13. 10.3390/microorganisms13030563
- Zhang Z, Li J, Wan Z, Fang S, Zhao Y, et al. subsp. BLa80 alleviates constipation in mice through modulating the stem cell factor (SCF)/c-Kit pathway and the gut microbiota. Food Funct. 2025;16:2347. 10.1039/d4fo06350c
- Ma W, Zhao Y, Liu Y, Wang Y, Yu S, et al. subsp. TG11 ameliorates loperamide-induced constipation in mice by modulating gut microbiota. Front Microbiol. 2025;16:1525887. 10.3389/fmicb.2025.1525887
- Zhang C, Wang L, Liu X, Wang G, Zhao J, et al. subsp. relieves loperamide hydrochloride-induced constipation in mice by enhancing bile acid dissociation. Food Funct. 2025;16:297. 10.1039/d4fo04660a
- Salo E, Roche D, Gomez-Martinez VB, Cruz-Domenech JM, Garcia-Mora LG, et al. Bifidobacterium animalis subsp. lactis BLa80 regulates the intestinal habit in adults with chronic constipation: a multicentre, randomised, double-blind, placebo-controlled study. Benef Microbes. 2024;15:679. 10.1163/18762891-bja00038
- Lan W, Yang H, Zhong Z, Luo C, Huang Q, et al. subsp. LPL-RH improves postoperative gastrointestinal symptoms and nutrition indexes by regulating the gut microbiota in patients with valvular heart disease: a randomized controlled trial. Food Funct. 2024;15:7605. 10.1039/d4fo01471e
- JanssenDuijghuijsen L, van den Belt M, Rijnaarts I, Vos P, Guillemet D, et al. Acacia fiber or probiotic supplements to relieve gastrointestinal complaints in patients with constipation-predominant IBS: a 4-week randomized double-blinded placebo-controlled intervention trial. Eur J Nutr. 2024;63:1983. 10.1007/s00394-024-03398-8
- Chen K, Zhou Z, Nie Y, Cao Y, Yang P, et al. Adjunctive efficacy of Bifidobacterium animalis subsp. lactis XLTG11 for functional constipation in children. Braz J Microbiol. 2024;55:1317. 10.1007/s42770-024-01276-3
- Lu Y, Zhou X, Wu Y, Cui Q, Tian X, et al. Metabolites 13,14-Dihydro-15-keto-PGE2 Participates in Bifidobacterium animalis F1-7 to Alleviate Opioid-Induced Constipation by 5-HT Pathway. Mol Nutr Food Res. 2024;68:e2200846. 10.1002/mnfr.202200846
- Skrzydło-Radomańska B, Prozorow-Król B, Kurzeja-Mirosław A, Cichoż-Lach H, Laskowska K, et al. The Efficacy and Safety of Single-Strain Probiotic Formulations Containing or in Adult Patients with Irritable Bowel Syndrome-A Randomized Double-Blind Placebo-Controlled Three-Arm Interventional Trial. J Clin Med. 2023;12. 10.3390/jcm12144838
- Watanabe M, Maruo T, Suzuki T. Effects of intake of subsp. FC on constipation symptoms and immune system in healthy participants with mild constipation: a double-blind, placebo-controlled study. Int J Food Sci Nutr. 2023;74:695. 10.1080/09637486.2023.2236805
- Jeong JJ, Ganesan R, Jin YJ, Park HJ, Min BH, et al. Multi-strain probiotics alleviate loperamide-induced constipation by adjusting the microbiome, serotonin, and short-chain fatty acids in rats. Front Microbiol. 2023;14:1174968. 10.3389/fmicb.2023.1174968
- Lai H, Li Y, He Y, Chen F, Mi B, et al. Effects of dietary fibers or probiotics on functional constipation symptoms and roles of gut microbiota: a double-blinded randomized placebo trial. Gut Microbes. 2023;15:2197837. 10.1080/19490976.2023.2197837
- Cui H, Wang Q, Feng C, Guo C, Zhang J, et al. Positive effect of subsp VHProbi YB11 in improving gastrointestinal movement of mice having constipation. Front Microbiol. 2022;13:1040371. 10.3389/fmicb.2022.1040371
- van der Schoot A, Helander C, Whelan K, Dimidi E. Probiotics and synbiotics in chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials. Clin Nutr. 2022;41:2759. 10.1016/j.clnu.2022.10.015
- Mitelmão FCR, Häckel K, Bergamaschi CC, Gerenutti M, Silva MT, et al. The effect of probiotics on functional constipation in adults: A randomized, double-blind controlled trial. Medicine (Baltimore). 2022;101:e31185. 10.1097/MD.0000000000031185
- Liao Y, Wang Y, Huang W, Wang J, Guo M, et al. L. acidophilus/L. johnsonii ratio affects slow transit constipation in rats. Sci Rep. 2024;14:21088. 10.1038/s41598-024-71945-8
- Gan D, Chen J, Tang X, Xiao L, Martoni CJ, et al. Impact of a probiotic chewable tablet on stool habits and microbial profile in children with functional constipation: A randomized controlled clinical trial. Front Microbiol. 2022;13:985308. 10.3389/fmicb.2022.985308
- Šola KF, Vladimir-Knežević S, Hrabač P, Mucalo I, Saso L, et al. The effect of multistrain probiotics on functional constipation in the elderly: a randomized controlled trial. Eur J Clin Nutr. 2022;76:1675. 10.1038/s41430-022-01189-0
- Lydia A, Indra TA, Rizka A, Abdullah M. The effects of synbiotics on indoxyl sulphate level, constipation, and quality of life associated with constipation in chronic haemodialysis patients: a randomized controlled trial. BMC Nephrol. 2022;23:259. 10.1186/s12882-022-02890-9
- Lin B, Zhao F, Liu Y, Wu X, Feng J, et al. Randomized Clinical Trial: Probiotics Alleviated Oral-Gut Microbiota Dysbiosis and Thyroid Hormone Withdrawal-Related Complications in Thyroid Cancer Patients Before Radioiodine Therapy Following Thyroidectomy. Front Endocrinol (Lausanne). 2022;13:834674. 10.3389/fendo.2022.834674
- Mokhtar NM, Jaafar NM, Alfian E, Mohd Rathi ND, Abdul Rani R, et al. Clinical assessment and cytokines level in constipation-predominant irritable bowel syndrome participants treated with Lactobacillus-containing cultured milk drink. Acta Gastroenterol Belg. 2021;84:585. 10.51821/84.4.009
- Martoni CJ, Evans M, Chow CT, Chan LS, Leyer G. Impact of a probiotic product on bowel habits and microbial profile in participants with functional constipation: A randomized controlled trial. J Dig Dis. 2019;20:435. 10.1111/1751-2980.12797
- Airaksinen K, Yeung N, Lyra A, Lahtinen SJ, Huttunen T, et al. The effect of a probiotic blend on gastrointestinal symptoms in constipated patients: a double blind, randomised, placebo controlled 2-week trial. Benef Microbes. 2019;10:617. 10.3920/BM2018.0163
- Leventogiannis K, Gkolfakis P, Spithakis G, Tsatali A, Pistiki A, et al. Effect of a Preparation of Four Probiotics on Symptoms of Patients with Irritable Bowel Syndrome: Association with Intestinal Bacterial Overgrowth. Probiotics Antimicrob Proteins. 2019;11:627. 10.1007/s12602-018-9401-3
- Kim BK, Choi IS, Kim J, Han SH, Suh HJ, et al. Effects of Fermented Milk with Mixed Strains as a Probiotic on the Inhibition of Loperamide-Induced Constipation. Korean J Food Sci Anim Resour. 2017;37:906. 10.5851/kosfa.2017.37.6.906
- Magro DO, de Oliveira LM, Bernasconi I, Ruela Mde S, Credidio L, et al. Effect of yogurt containing polydextrose, Lactobacillus acidophilus NCFM and Bifidobacterium lactis HN019: a randomized, double-blind, controlled study in chronic constipation. Nutr J. 2014;13:75. 10.1186/1475-2891-13-75
- Ohigashi S, Hoshino Y, Ohde S, Onodera H. Functional outcome, quality of life, and efficacy of probiotics in postoperative patients with colorectal cancer. Surg Today. 2011;41:1200. 10.1007/s00595-010-4450-6
- Choi SC, Kim BJ, Rhee PL, Chang DK, Son HJ, et al. Probiotic Fermented Milk Containing Dietary Fiber Has Additive Effects in IBS with Constipation Compared to Plain Probiotic Fermented Milk. Gut Liver. 2011;5:22. 10.5009/gnl.2011.5.1.22
- Nova E, Viadel B, Wärnberg J, Carreres JE, Marcos A. Beneficial effects of a synbiotic supplement on self-perceived gastrointestinal well-being and immunoinflammatory status of healthy adults. J Med Food. 2011;14:79. 10.1089/jmf.2008.0328
- Jeon JR, Choi JH. Lactic acid fermentation of germinated barley fiber and proliferative function of colonic epithelial cells in loperamide-induced rats. J Med Food. 2010;13:950. 10.1089/jmf.2009.1307
- Xia T, Huang F, Yun F, Liu Y, Wang T, et al. LRJ-1 alleviates constipation through promoting gut -derived γ-aminobutyric acid production. Curr Res Food Sci. 2024;9:100924. 10.1016/j.crfs.2024.100924
- Kwon H, Nam EH, Kim H, Jo H, Bang WY, et al. Effect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial. Sci Rep. 2024;14:22384. 10.1038/s41598-024-72887-x
- Cheng S, Cui H, Zhang J, Wang Q, Duan Z. Probiotic potential of Lacticaseibacillus rhamnosus VHProbi M15 on sucralfate-induced constipation in mice. Sci Rep. 2024;14:1131. 10.1038/s41598-024-51497-7
- Gu Y, Qin X, Zhou G, Wang C, Mu C, et al. GG supernatant promotes intestinal mucin production through regulating 5-HT4R and gut microbiota. Food Funct. 2022;13:12144. 10.1039/d2fo01900k
- Wang J, Yin L, Zheng W, Shi S, Hao W, et al. Lactobacillus rhamnosus GG normalizes gut dysmotility induced by environmental pollutants via affecting serotonin level in zebrafish larvae. World J Microbiol Biotechnol. 2022;38:222. 10.1007/s11274-022-03409-y
- Petersen AØ, Jokinen M, Plichta DR, Liebisch G, Gronwald W, et al. Cytokine-specific autoantibodies shape the gut microbiome in autoimmune polyendocrine syndrome type 1. J Allergy Clin Immunol. 2021;148:876. 10.1016/j.jaci.2021.03.025
- Rodríguez Arreola A, Solís Pacheco JR, Lacroix M, Balcazar López E, Navarro Hernández RE, et al. In vivo assessment and characterization of lactic acid bacteria with probiotic profile isolated from human milk powder. Nutr Hosp. 2021;38:152. 10.20960/nh.03335
- Reyna-Figueroa J, Bejarano-Juvera AA, García-Parra C, Barrón-Calvillo EE, Queipo-Garcia GE, et al. Decrease of Postchemotherapy Complications With the Use of Probiotics in Children With Acute Lymphoblastic Leukemia. J Pediatr Hematol Oncol. 2021;43:e457. 10.1097/MPH.0000000000001956
- Reyna-Figueroa J, Barrón-Calvillo E, García-Parra C, Galindo-Delgado P, Contreras-Ochoa C, et al. Probiotic Supplementation Decreases Chemotherapy-induced Gastrointestinal Side Effects in Patients With Acute Leukemia. J Pediatr Hematol Oncol. 2019;41:468. 10.1097/MPH.0000000000001497
- Vitellio P, Celano G, Bonfrate L, Gobbetti M, Portincasa P, et al. Effects of and on Gut Microbiota in Patients with Lactose Intolerance and Persisting Functional Gastrointestinal Symptoms: A Randomised, Double-Blind, Cross-Over Study. Nutrients. 2019;11. 10.3390/nu11040886
- Baştürk A, Artan R, Atalay A, Yılmaz A. Investigation of the efficacy of synbiotics in the treatment of functional constipation in children: a randomized double-blind placebo-controlled study. Turk J Gastroenterol. 2017;28:388. 10.5152/tjg.2017.17097
- Wojtyniak K, Horvath A, Dziechciarz P, Szajewska H. Lactobacillus casei rhamnosus Lcr35 in the Management of Functional Constipation in Children: A Randomized Trial. J Pediatr. 2017;184:101. 10.1016/j.jpeds.2017.01.068
- Goldenberg JZ, Lytvyn L, Steurich J, Parkin P, Mahant S, et al. Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database Syst Rev. 2015. 10.1002/14651858.CD004827.pub4
- Yang W, Gao X, Lin J, Liu L, Peng L, et al. Water-insoluble dietary fiber from walnut relieves constipation through Limosilactobacillus reuteri-mediated serotonergic synapse and neuroactive ligand-receptor pathways. Int J Biol Macromol. 2024;283:137931. 10.1016/j.ijbiomac.2024.137931
- Tyrsin OY, Tyrsin DY, Nemenov DG, Ruzov AS, Odintsova VE, et al. Effect of Lactobacillus reuteri NCIMB 30351 drops on symptoms of infantile functional gastrointestinal disorders and gut microbiota in early infants: Results from a randomized, placebo-controlled clinical trial. Eur J Pediatr. 2024;183:2311. 10.1007/s00431-024-05473-y
- Ismail NI, Nawawi KNM, Hsin DCC, Hao KW, Mahmood NRKN, et al. Probiotic containing Lactobacillus reuteri DSM 17648 as an adjunct treatment for Helicobacter pylori infection: A randomized, double-blind, placebo-controlled trial. Helicobacter. 2023;28:e13017. 10.1111/hel.13017
- Žaja O, Fiolić M, Ćuk MC, Tiljak MK. "The role of L. reuteri DSM17938 in nutritional recovery and treatment of constipation in children and adolescents with anorexia nervosa - a randomized, double blind, placebo controlled study". Clin Nutr ESPEN. 2021;46:47. 10.1016/j.clnesp.2021.08.016
- Vandenplas Y, Gerlier L, Caekelbergh K, Possner M. An Observational Real-Life Study with a New Infant Formula in Infants with Functional Gastro-Intestinal Disorders. Nutrients. 2021;13. 10.3390/nu13103336
- Saviano A, Brigida M, Migneco A, Gunawardena G, Zanza C, et al. Lactobacillus Reuteri DSM 17938 in Diarrhea and Constipation: Two Sides of the Same Coin?. Medicina (Kaunas). 2021;57. 10.3390/medicina57070643
- Kubota M, Ito K, Tomimoto K, Kanazaki M, Tsukiyama K, et al. Lactobacillus reuteri DSM 17938 and Magnesium Oxide in Children with Functional Chronic Constipation: A Double-Blind and Randomized Clinical Trial. Nutrients. 2020;12. 10.3390/nu12010225
- West CL, Stanisz AM, Mao YK, Champagne-Jorgensen K, Bienenstock J, et al. Microvesicles from Lactobacillus reuteri (DSM-17938) completely reproduce modulation of gut motility by bacteria in mice. PLoS One. 2020;15:e0225481. 10.1371/journal.pone.0225481
- Riezzo G, Chimienti G, Orlando A, D'Attoma B, Clemente C, et al. Effects of long-term administration of Lactobacillus reuteri DSM-17938 on circulating levels of 5-HT and BDNF in adults with functional constipation. Benef Microbes. 2019;10:137. 10.3920/BM2018.0050
- Jadrešin O, Sila S, Trivić I, Mišak Z, Hojsak I, et al. Lack of Benefit of Lactobacillus reuteri DSM 17938 as an Addition to the Treatment of Functional Constipation. J Pediatr Gastroenterol Nutr. 2018;67:763. 10.1097/MPG.0000000000002134
- Riezzo G, Orlando A, D'Attoma B, Linsalata M, Martulli M, et al. Randomised double blind placebo controlled trial on Lactobacillus reuteri DSM 17938: improvement in symptoms and bowel habit in functional constipation. Benef Microbes. 2018;9:51. 10.3920/BM2017.0049
- Ojetti V, Petruzziello C, Migneco A, Gnarra M, Gasbarrini A, et al. Effect of Lactobacillus reuteri (DSM 17938) on methane production in patients affected by functional constipation: a retrospective study. Eur Rev Med Pharmacol Sci. 2017;21:1702.
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