NOW Supplements, Quercetin with Bromelain

Quercetin shows promise for bronchitis

Likely Very Effective

Based on 1 Researches

USERS' SCORE

Excellent

Based on 23 Reviews

Integrating serum pharmacochemistry, network pharmacology and untargeted metabolomics strategies to reveal the material basis and mechanism of action of Feining keli in the treatment of chronic bronchitis.

Most Relevant Research

We aimed to gather insights into how quercetin, a component of the herbal preparation Feining Keli (FNKL), may influence chronic bronchitis (CB) treatment. In our study, a rat model of CB was created using a combination of nasal drops of lipopolysaccharide (LPS) and smoking exposure. This model allowed us to evaluate the effectiveness of FNKL in a controlled environment, assessing behavioral changes, body mass, and lung health through various examinations.

Our findings indicated that FNKL has positive effects on CB, showing a potential benefit in alleviating symptoms. One crucial element we identified was quercetin-3-galactoside, which appears to play a significant role in FNKL's effectiveness. We discovered that quercetin might help by reducing inflammation and oxidative stress while regulating metabolic activity associated with bronchitis.

However, it’s important to note that while quercetin is active within the FNKL complex, our study does not isolate its effects from other ingredients. This means that while its importance is highlighted, we cannot conclusively determine quercetin’s standalone effectiveness in treating bronchitis.

9.5

Saved my asthma

Most Useful Review

Quercetin and bromelain are potent natural ingredients that help manage allergic and inflammatory disorders like bronchitis. They alleviate asthma symptoms and assist in phlegm elimination. With arthritis, Raynaud's syndrome, and various allergies, Quercetin has been a lifesaver for me, and I take it regularly. Highly recommended!

Knee Pain

I take one tablet 20 minutes before meals, twice a day. It’s essential in the morning before breakfast, and before lunch and dinner as well. I feel a surge of strength, and it has helped with allergies. While taking this, my knee pain disappeared.

Asthma

Quercetin alleviates asthma symptoms

Based on 10 Researches

Quercetin inhibits ferroptosis through the SIRT1/Nrf2/HO-1 signaling pathway and alleviates asthma disease.

Most Relevant Research

We explored how quercetin, a natural compound found in fruits and vegetables, can impact asthma symptoms. Using an ovalbumin-induced mouse model of asthma, we aimed to uncover whether quercetin can help inhibit a process known as ferroptosis, potentially offering a new therapeutic approach for asthma sufferers.

Our findings showed that quercetin effectively reduced inflammation in the asthmatic mice. Specifically, it lowered levels of inflammatory factors such as IL-4, IL-5, and IL-13—substances typically elevated during an asthma attack. Notably, we also observed that quercetin increased the levels of superoxide dismutase, an important antioxidant, while decreasing malondialdehyde and ferric ions that are associated with oxidative stress.

Additionally, quercetin appeared to boost the expression of key proteins involved in defending against oxidative stress, specifically SIRT1, Nrf2, and HO-1. This suggests that quercetin not only helps combat inflammation but may also protect against cellular damage within the lungs. Overall, our study indicates that quercetin holds promise as a beneficial treatment for asthma by addressing both inflammatory and oxidative stress pathways.

9.5

Effective for allergies

Most Useful Review

Quercetin and bromelain are potent natural ingredients that alleviate allergic and inflammatory disorders like asthma. As someone with arthritis and multiple allergies, Quercetin has been my salvation. I take it regularly and highly recommend it!

In-silico exploring pathway and mechanism-based therapeutics for allergic rhinitis: Network pharmacology, molecular docking, ADMET, quantum chemistry and machine learning based QSAR approaches.

Most Relevant Research

We delved into the potential of quercetin as a therapeutic option for treating allergic rhinitis, a common condition affecting roughly 40% of the global population. This study utilized various in-silico approaches, such as network pharmacology and molecular docking, to identify compounds from traditional medicinal plants and assess their effectiveness.

Among the 241 compounds analyzed, quercetin stood out due to its strong binding affinities with important targets linked to inflammatory and immune pathways. Our assessments indicated that quercetin could interact effectively with key cytokines involved in allergic reactions, potentially reducing allergy symptoms.

While the study highlighted promising implications for quercetin, it did not isolate its effects from other examined compounds. Therefore, further experimental testing is needed to affirm its benefits and effectiveness in real-world allergy treatment situations.

8.8

Effective for allergies

Most Useful Review

Excellent tool! Before ordering this drug, I read that Quercetin with Bromelain strengthens the immune system and helps with allergies. Since I started taking one capsule per day, my allergy symptoms have improved within a week. I'm looking forward to the ageing benefits too. Thank you for the excellent service!

Arthritis

Quercetin nanoparticles reduce senescence

Based on 16 Researches

Nanoparticle-delivered quercetin exhibits enhanced efficacy in eliminating iron-overloaded senescent chondrocytes.

Most Relevant Research

We explored the effects of quercetin, a natural compound with potential benefits for treating osteoarthritis (OA), specifically focusing on its ability to target damaged chondrocytes, the cartilage cells that play a crucial role in joint health. In our study, we utilized specialized nanoparticles to increase the effectiveness of quercetin, overcoming its usual limitations related to absorption and bioavailability.

Our research involved subjecting human chondrocytes to conditions that mimic OA. Afterward, we treated them with either free quercetin or our quercetin-loaded nanoparticles (Q-NP). We found that the Q-NP not only allowed for better cellular absorption but also selectively induced apoptosis, or programmed cell death, in senescent chondrocytes. This is significant because eliminating these unhealthy cells could pave the way for healthier joint repair and function.

In addition to promoting cell death in the right cells, Q-NP led to an increase in oxidative stress and reduced key markers of cellular aging. We also noted that the treatment halted the cell cycle in cells that needed to be eliminated. Overall, our findings suggest that enhancing quercetin delivery through nanoparticles holds great promise for improving osteoarthritis outcomes by actively removing harmful senescent cells from joint tissues.

9.5

Significant relief

Most Useful Review

Quercetin and bromelain are potent natural ingredients that alleviate allergic and inflammatory disorders, including arthritis. They help mitigate asthma, eczema, and other conditions. As someone suffering from arthritis, Raynaud's syndrome, and various allergies, I find Quercetin a real lifesaver. I take it regularly and wholeheartedly recommend it!

Breast Cancer

I chose this quercetin product as it was your top seller. I'm using this flavonoid with others to tackle my incurable advanced breast cancer. The pain in my legs and feet is definitely lessening, which is wonderful. My oncologist had expected I would not survive past early 2020. I'm extremely pleased with the effects of this product.

Chronic Cough

Effective against allergies

An excellent tool! After three months, I can properly evaluate this drug. I used it for chronic cough due to allergies, particularly ragweed. My son has chronic obstructive bronchitis and found it very helpful as an expectorant. We survived allergy season and are now using it for immunity alongside vitamins C and D. We feel great!

Heart Attack

Supports heart health

I have been taking quercetin since September 2020. I use this drug alongside Quercetin from Paradise Herbs for my varicose veins, preparing for surgery. My recent ultrasound showed calm vessels without inflammation, and my heart scan was normal. After four cycles of chemotherapy, I believe this supplement, along with others, helped reduce my inflammation and support my heart. Be healthy and enjoy life!

Irritable Bowel Syndrome

Quercetin and bromelain are powerful natural ingredients that alleviate allergic and inflammatory disorders, including irritable bowel syndrome. As someone with arthritis and allergies, Quercetin has been a salvation for me. I take it regularly and recommend it for its benefits.

Pneumonia

I read about the benefits of Quercetin for pneumonia, so my wife and I used it for lung inflammation. Quercetin was taken alongside vitamin D3. I believe it was this antioxidant that aided our recovery.

Urinary Tract Infection

This dietary supplement has transformed my life. The combination of quercetin and bromelain is ideal for absorption. I take it for painful bladder syndrome, resulting in repeated cystitis without bacteria. Quercetin's anti-inflammatory properties have removed my pain after just three weeks of use, and I'm thrilled with the results.

Vertigo

Bromelain shows mixed effectiveness

Based on 1 Researches

'Complementary ENT': a systematic review of commonly used supplements.

Most Relevant Research

We explored the effectiveness of bromelain, a pineapple enzyme, in alleviating symptoms of vertigo. One significant study focused on 116 children suffering from acute sinusitis. The trial compared the effects of bromelain on its own with bromelain combined with standard treatments, and also measured its impact against standard therapy alone.

The findings indicated that children receiving bromelain monotherapy experienced faster recovery compared to those in the other treatment groups. However, since bromelain was tested alongside standard therapy, discerning its isolated effect on vertigo remains somewhat challenging.

Overall, while there seems to be a positive outcome associated with bromelain treatment in this context, further research is necessary to clarify its specific benefits for vertigo on its own.

9.5

Effective treatment

Most Useful Review

Helps my vertigo; I take this twice a day. It usually keeps the vertigo at bay, but if it resurfaces, I increase my dose to two capsules twice daily, which often resolves it immediately.

Whooping Cough

Quartztin was prescribed by my doctor for my two-month battle with whooping cough. It worked quickly; within two days, I was sleeping soundly and my cough had vanished completely in a week. I even started giving it to my daughter, and by day three, her cough was gone too.

Brain Tumor

Supports brain health

I introduced it to my husband as a cleaning aid, and he decided to try it too. Quercetin reduces oxidative processes in the body, possesses anti-inflammatory properties, and strengthens blood vessels. It protects brain cells against damage, reduces bad cholesterol, controls blood pressure, and combats viruses. Combined with vitamin C, it offers strong protection, particularly beneficial for brain tumour treatment.

Bursitis

I'm genuinely surprised at how well this works. I can finally use my hands again, and my bursitis in the left hip has completely disappeared. It's also effective for allergies.

Cancer

Quercetin's role against colorectal cancer

Based on 16 Researches

Structure-activity relationship analysis of mono-methylated quercetins by comprehensive MS/MS analysis and anti-proliferative efficacy in human colorectal cancer cells.

Most Relevant Research

We aimed to understand how quercetin and its derivatives, especially mono-methylated quercetins (MQs), might help in treating colorectal cancer. Using advanced techniques like tandem mass spectrometry, we identified specific structural features of these flavonoids that could enhance their anti-cancer activities.

Our findings showed that methylation at specific positions on the quercetin molecule significantly improved its ability to fight cancer cells. Notably, 3-O-methylquercetin and 4'-O-methylquercetin were particularly effective. These compounds caused cancer cells to stop dividing and triggered programmed cell death, also known as apoptosis.

We observed that these MQs worked through several mechanisms, such as inducing oxidative stress, disrupting mitochondrial function, and inactivating cancer-related signaling pathways—all while being non-toxic to normal human colon cells. This makes them promising candidates for cancer therapy, especially for patients with colorectal cancer.

Ultimately, our research revealed that small modifications in flavonoid structures could lead to significant improvements in their anti-cancer effectiveness, providing a path for developing targeted treatments for colorectal cancer.

8.8

Improved wellbeing

Most Useful Review

I have multiple sclerosis, but this supplement has been stunningly effective. At 52, my health has improved significantly. Quercetin, a powerful antioxidant, along with bromelain, is helping my treatment against cancer. I only relied on these supplements and avoided antibiotics throughout my recovery. I consistently take them for ongoing health and quality of life.

Ear Infection

I have an ear infection that caused dizziness and imbalance when lying down or moving my head. After taking one capsule, I noticed a significant improvement in my balance within an hour. I then increased to two capsules daily, and thankfully, the dizziness completely disappeared, returning mildly only if I forget to take them.

Gout

Quercetin alleviates gout symptoms

Based on 11 Researches

Quercetin inhibits gout arthritis in mice: induction of an opioid-dependent regulation of inflammasome.

Most Relevant Research

We explored the effects of quercetin, a natural compound, on gout arthritis induced by monosodium urate (MSU) crystals. Our research specifically looked at how quercetin alleviates pain and inflammation associated with gout while examining its interaction with naloxone, a substance known to block opioid receptors.

Mice were treated with quercetin, and we assessed their pain sensitivity from 1 to 24 hours post-MSU injection. Our observations included evaluating the recruitment of white blood cells, levels of inflammatory cytokines, oxidative stress, and activation of certain molecular pathways in the knee joints, all measured at 24 hours after the MSU was introduced.

The results were promising: quercetin effectively reduced MSU-induced pain, inflammation, and related oxidative stress. Notably, the presence of naloxone seemed to negate these benefits, indicating that quercetin's effects are linked to opioid pathways. These findings suggest that quercetin could be a valuable therapeutic option for managing gout symptoms, highlighting its dual role as both an analgesic and anti-inflammatory agent.

9.5

Swelling reduced

Most Useful Review

I suffer from recurring gout. My latest episode affected my right hand, making it unusable. After learning about Quercetin, I ordered a bottle. Within three days, my swelling and pain significantly decreased, and I regained full use of my hand.

Hypothyroidism

Quercetin reverses hyperthyroid damage

Possibly Effective

Based on 7 Researches

Quercetin alleviates hyperthyroidism-induced liver damage via Nrf2 Signaling pathway.

Most Relevant Research

We examined the effects of quercetin, a plant-derived flavonoid known for its antioxidant properties, in treating hyperthyroidism induced by L-thyroxine (LT4) in rats. Through a carefully designed study, we administered quercetin at different doses over two weeks to observe its impact on thyroid dysfunction.

The findings were striking. We noted that LT4 injections raised thyroid hormone levels while simultaneously increasing oxidative stress markers and decreasing antioxidant activity. However, when quercetin was introduced, it effectively reversed these adverse effects. Specifically, we saw improvements in liver function and oxidative stress markers, which suggests that quercetin held protective properties against the liver damage associated with hyperthyroidism.

Moreover, it became clear that these beneficial effects were tied to a specific signaling pathway known as Nrf2. When Nrf2 was inhibited in certain experimental rats, the positive impact of quercetin diminished, reinforcing the significance of this pathway in quercetin's action. Therefore, while our focus was on hyperthyroidism, the results imply that quercetin may hold potential therapeutic value in related conditions like hypothyroidism as well.

9.5

Improved energy levels

Most Useful Review

I started taking this quercetin for my hypothyroidism after experiencing severe fatigue and a racing heart, yet my thyroid hormones were normal. I added magnesium and vitamin D to my regimen. Within a week, I began feeling more energetic and cheerful, and I stopped needing daytime naps. The magnesium course didn't help previously, but now I feel completely different. The combination of supplements may have made a difference. I'm pleased with the outcome and plan to keep taking it!

Kidney Stones

Quercetin with Bromelain is excellent for the kidneys. I take it regularly as I aim to strengthen my kidneys and ward off kidney stones.

Lung Cancer

I chose this quercetin product as it was your number one bestseller. I am using this flavonoid to combat my advanced prostate cancer. The pain in my legs and feet is definitely lessening, which is wonderful. My oncology professor originally predicted I would not survive past early 2020. I’m very pleased with the results from taking this product.

Multiple Sclerosis

Reduced allergy symptoms

Quercetin has significantly reduced my allergy symptoms, including sneezing and coughing. I have multiple pollen allergies, but since taking 3 to 6 capsules daily, my symptoms have improved by at least 70%. Although I still contend with other airborne allergies, Quercetin makes it easier to manage my reactions and triggers.

Tinnitus

After suffering from tinnitus, I noticed it flaring up when I felt down. Since taking bromelain regularly, the symptoms have significantly diminished.

Constipation

Relieved constipation

Taking 50 mg of chelated iron significantly eased my stubborn constipation. Combined with probiotics, it helped promote regularity. I initially took quercetin before lunch to improve my gut health, and I recommend it for anyone struggling with iron-related constipation.

Eczema

Quercetin shows promise for eczema

Based on 1 Researches

Antioxidant Activity of Quercetin-Containing Liposomes-in-Gel and Its Effect on Prevention and Treatment of Cutaneous Eczema.

Most Relevant Research

We investigated the potential of quercetin, a natural compound known for its antioxidant properties, in treating cutaneous eczema. Specifically, we prepared a special formulation of quercetin contained within liposomes and mixed it into a gel. This method aimed to enhance the compound's effectiveness in promoting skin healing.

Our findings revealed that this quercetin-infused gel not only demonstrated significant antioxidant activity but also improved skin conditions in mice suffering from eczema. The application of this formulation led to noteworthy reductions in various symptoms associated with the skin condition, such as inflammation and epidermal peeling.

In comparison to a commonly used eczema treatment, we found that the quercetin formulation outperformed the commercially available steroid cream in reducing malondialdehyde levels, a marker of oxidative stress in the body. These results suggest that quercetin-containing liposomes hold promise as a novel approach for preventing and treating cutaneous eczema.

8.8

Relieves eczema symptoms

Most Useful Review

Quercetin is truly remarkable for addressing allergic and inflammatory conditions, including eczema. It has greatly alleviated my eczema symptoms, helping with my arthritis and allergies. I consistently take it and wholeheartedly recommend it!

Leg Cramps

I drink a complex for my blood vessels along with vitamins, ovtin, bioflavonoids, green tea extract, and grape seed extract. After a week, my legs feel lighter, and I no longer experience leg cramps.

Hives

I have been suffering from hives for three years without an identified cause. Conventional medicine failed to help, but after taking a quercetin supplement, I've noticed almost all the spots have disappeared within a week. Stay healthy!

Hyperthyroidism

A good supplement that I use as directed by my nutritionist. It effectively helps with my hyperthyroidism. I follow courses lasting 2-3 months.

Liver Disease

I've repurchased quercetin with bromelain for its enhanced anti-inflammatory properties. Quercetin improves blood circulation and helps alleviate allergy symptoms, while bromelain aids digestion. Together, they support overall wellness, prevent lifestyle-related diseases, and enhance immunity. However, care should be taken to avoid overdosing, as effects are confirmed in healthy individuals only.

Prostate Cancer

I chose this quercetin product as it's a best-seller. I’m using it alongside other supplements to combat my incurable advanced prostate cancer. I'm pleased to report that the pain in my legs and feet is diminishing. My oncology professor had predicted I wouldn't survive past early 2020, so I am very satisfied with this product's impact.

Bone Pain

I suffer from recurring gout, and my last bout affected my right hand. After taking quercetin for three days, the swelling and pain have significantly reduced, and I have regained full use of my hand.

Cold Sores

Effective for allergies

A very good remedy for allergies. It effectively helps me manage cold allergies. I take one capsule at the onset of cold weather.

Diabetes