 NOW Foods, Pantothenic Acid, 500 mg, 100 Veg Capsules |
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Calcium affects brain tumor growth
Modeling craniopharyngioma for drug screening reveals a neuronal mechanism for tumor growth.
We developed two unique animal models to explore how calcium influences tumor expansion, particularly in craniopharyngioma, a type of brain tumor notoriously known for invading the hypothalamus. This research aimed to understand whether the activity of neuroendocrine neurons impacts tumor growth.
During our study, we conducted a thorough high-throughput drug screening process and identified 74 compounds with significant antitumor properties. Among these, we found that the drug amlodipine besylate was particularly effective. Its administration led to tumor regression, possibly by influencing calcium transients and the chemical interactions between neurons and tumor cells.
Interestingly, we observed that manipulating neuroendocrine neuronal activity could either promote or slow down tumor growth, indicating that craniopharyngioma tumors can exploit these neurons to aid in their progression. Overall, these findings provide deeper insight into tumor biology and suggest potential pathways for developing effective treatments.
Effective natural remedy
Most Useful Review
50 people found this helpful
My daughter was diagnosed with ADHD several years ago, and I was initially opposed to medication. My husband, knowledgeable about natural supplements, introduced her to DMAE and Pantothenic Acid (Vitamin B5), which seem to work better than any ADHD medication available. Now at 16, she takes 3 DMAE 250mg capsules and 3 Pantothenic Acid 500mg capsules daily. The difference is noticeable; everyone can tell when she hasn’t taken her vitamins!
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 Jarrow Formulas, B-Right, 100 Veggie Capsules |
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Pyridoxine promotes glioblastoma cell death
Effect of pyridoxine or cobalamin supplementation on apoptosis and cell cycle progression in a human glioblastoma cell line.
We explored the effect of vitamin B6 (pyridoxine) and B12 (cobalamin) on human glioblastoma cells, known for their aggressive nature. By treating cell cultures with varying doses of these vitamins over 24-72 hours, we aimed to see how they influenced cell survival and progression through their life cycle.
Our findings revealed that pyridoxine significantly reduced cell viability, likely due to inducing apoptosis, while cobalamin demonstrated some protective qualities against this effect. Although cobalamin did not boost apoptosis directly, it did intervene in the negative impact of pyridoxine on cell viability.
Transformed my life
Most Useful Review
7 people found this helpful
Changed My Life! I have tried every type of B12 vitamin available; including injectable options and designer prescription varieties. This is the only B12 supplement that has been effective for me. I am not usually one to write reviews, but this has genuinely changed my life. I transitioned from being barely able to manage fatigue to actively participating in life again. The brain fog is gone, and I finally feel like I've regained control of my life.
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 Life Extension, BioActive Complete B-Complex, 60 Vegetarian Capsules |
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Pyridoxine promotes glioblastoma cell death
Effect of pyridoxine or cobalamin supplementation on apoptosis and cell cycle progression in a human glioblastoma cell line.
We explored the effect of vitamin B6 (pyridoxine) and B12 (cobalamin) on human glioblastoma cells, known for their aggressive nature. By treating cell cultures with varying doses of these vitamins over 24-72 hours, we aimed to see how they influenced cell survival and progression through their life cycle.
Our findings revealed that pyridoxine significantly reduced cell viability, likely due to inducing apoptosis, while cobalamin demonstrated some protective qualities against this effect. Although cobalamin did not boost apoptosis directly, it did intervene in the negative impact of pyridoxine on cell viability.
Relief and improvement
Most Useful Review
6 people found this helpful
I follow the keto diet and have a fibroid tumour in my uterus. The doctor prescribed this product, and I found it to be wonderful. I experienced significant relief, and my health and mental state improved. The tumour is small, and I highly recommend it. The quality is excellent, the ingredients are good, and the quantity is sufficient. There is no noticeable taste, and the packaging is nice.
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 NOW Foods, Flush-Free Niacin, 250 mg, 180 Veg Capsules |
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INPP5E's impact on medulloblastoma
A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma.
We examined how INPP5E influences Sonic Hedgehog (SHH) signaling in medulloblastoma, a common pediatric brain tumor. By using a murine model, we found that deleting INPP5E reduced tumor growth, cell proliferation, and SHH signaling while causing a loss of cilia on tumor cells.
Our findings suggest that INPP5E is crucial for maintaining primary cilia and promoting tumor progression. Interestingly, we observed that lower levels of INPP5E in human samples correlated with better survival outcomes, highlighting its potential as a therapeutic target in combating SHH medulloblastoma.
Lighter brain feeling
Most Useful Review
This product is flash-free and safe, ideal for physical and mental disorders resulting from dopamine overactivity. My brain felt noticeably lighter after use.
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 NOW Foods, B-100, 100 Veg Capsules |
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Immediate brain benefits
Most Useful Review
2 people found this helpful
I highly recommend it; it's incredibly beneficial for the brain, and I've noticed the difference right away.
Brain enhancement
Most Useful Review
1 people found this helpful
It's fantastic for the brain; I definitely recommend it.
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 NOW Foods, Biotin, 1,000 mcg, 100 Veg Capsules |
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Relief noted
Most Useful Review
3 people found this helpful
I took it on my doctor's advice due to my thyroid disease, using Bach’s extracts from an Instagram account. Many claimed to have recovered, and I had a small tumour beside my neck. Upon using the extract, I felt completely relieved. I was advised to take Haldi, Biotin of size 1000, and magnesium from the Now Company. Since then, I've noticed increased activity levels and lost one and a half kilograms. I'm eager for the month to end so that I can get tested. Pray for my recovery, Lord.
Focus improvement
Most Useful Review
Most people use Biotin for skin and hair health. Personally, I take it as a brain energiser, which helps me focus! If you're experiencing brain fog, you might want to try it.
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 NOW Foods, Zinc, 50 mg, 250 Tablets |
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Zinc aids in glioblastoma treatment
Ketogenic diet with oxyresveratrol and zinc inhibits glioblastoma and restores memory function and motor coordination.
We evaluated the potential of zinc in combination with a ketogenic diet and oxyresveratrol in fighting glioblastoma, a highly aggressive brain tumor. Through a series of carefully designed experiments, we examined how these treatments affect tumor growth and overall brain function.
In our study, we induced brain tumors in Wistar rats and then applied our treatment regimen. We tracked various outcomes, including tumor size, proliferation rates, memory function, and motor coordination. By assessing glucose and ketone levels, we gained insights into the metabolic changes occurring as a result of the treatments.
The findings suggested that zinc played a supportive role alongside the ketogenic diet and oxyresveratrol in reducing tumor growth. Moreover, these treatments appeared to enhance memory and motor coordination, indicating a multi-faceted benefit. Overall, this progression offered valuable information about the role of diet and supplementary compounds in battling aggressive brain tumors like glioblastoma.
Improves focus
Most Useful Review
This zinc supplement features impressive packaging and composition, primarily strengthening immunity and supporting skin, hair, and hormonal balance. It enhances memory and brain function, improving focus and concentration. Additionally, it accelerates wound healing, making it a well-rounded product for overall health.
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 Solgar, Chelated Zinc, 22 mg, 250 Tablets |
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Zinc aids in glioblastoma treatment
Ketogenic diet with oxyresveratrol and zinc inhibits glioblastoma and restores memory function and motor coordination.
We evaluated the potential of zinc in combination with a ketogenic diet and oxyresveratrol in fighting glioblastoma, a highly aggressive brain tumor. Through a series of carefully designed experiments, we examined how these treatments affect tumor growth and overall brain function.
In our study, we induced brain tumors in Wistar rats and then applied our treatment regimen. We tracked various outcomes, including tumor size, proliferation rates, memory function, and motor coordination. By assessing glucose and ketone levels, we gained insights into the metabolic changes occurring as a result of the treatments.
The findings suggested that zinc played a supportive role alongside the ketogenic diet and oxyresveratrol in reducing tumor growth. Moreover, these treatments appeared to enhance memory and motor coordination, indicating a multi-faceted benefit. Overall, this progression offered valuable information about the role of diet and supplementary compounds in battling aggressive brain tumors like glioblastoma.
Essential for brain
Most Useful Review
This high-quality zinc supplement is fantastic; it increases immunity and is essential for brain function and physical activity.
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 Doctor's Best, High Absorption Zinc Bisglycinate, 50 mg, 90 Veggie Caps |
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Zinc aids in glioblastoma treatment
Ketogenic diet with oxyresveratrol and zinc inhibits glioblastoma and restores memory function and motor coordination.
We evaluated the potential of zinc in combination with a ketogenic diet and oxyresveratrol in fighting glioblastoma, a highly aggressive brain tumor. Through a series of carefully designed experiments, we examined how these treatments affect tumor growth and overall brain function.
In our study, we induced brain tumors in Wistar rats and then applied our treatment regimen. We tracked various outcomes, including tumor size, proliferation rates, memory function, and motor coordination. By assessing glucose and ketone levels, we gained insights into the metabolic changes occurring as a result of the treatments.
The findings suggested that zinc played a supportive role alongside the ketogenic diet and oxyresveratrol in reducing tumor growth. Moreover, these treatments appeared to enhance memory and motor coordination, indicating a multi-faceted benefit. Overall, this progression offered valuable information about the role of diet and supplementary compounds in battling aggressive brain tumors like glioblastoma.
Improves sleep quality
Most Useful Review
Zinc has a stabilising effect on conditions like insomnia, depression, and other disorders, including those during menopause or old age. The natural ingredients are effective in relieving stress, stimulating brain function, improving concentration, and elevating performance. The medium-sized capsules contain GABA, which enhances sleep quality by limiting stress effects, ensuring deeper, more restorative sleep. The dosage is well-calibrated.
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 NOW Foods, CoQ10, 100 mg, 50 Softgels |
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CoQ10 reduces glioblastoma growth
CoQ reduces glioblastoma growth and infiltration through proteome remodeling and inhibition of angiogenesis and inflammation.
The study focused on understanding how coenzyme Q10 (CoQ) could help manage glioblastoma, a particularly challenging type of brain tumor. We utilized xenograft models with U251 cells implanted in mice to observe tumor growth, inflammation, and vascular changes, alongside assessing the effects of CoQ on various related behaviors, including cell migration and invasion.
We found that CoQ treatment significantly reduced tumor volume in both xenograft and orthotopic models. Interestingly, while it did not directly hinder tumor cell proliferation, it was effective in creating a less hypoxic and vascularized environment. This indicates that CoQ can influence the tumor’s growth dynamics by targeting the underlying conditions that support tumor survival and expansion.
Additionally, CoQ treatment led to a noticeable downregulation of proteins involved in inflammation and angiogenesis, like HIF-1α and NF-kB. This change in molecular activity caused an entire reshaping of the tumor's protein landscape, ultimately impacting how the tumor interacts with its environment. Notably, we observed a restriction in tumor cell migration and invasion, attributed to changes in the cell's structural components.
Overall, our findings suggest that incorporating CoQ into current treatment protocols could provide a holistic approach to combat glioblastoma by simultaneously addressing multiple pathways that facilitate tumor growth and infiltration.
Significant improvement
Most Useful Review
1 people found this helpful
Highly recommended! NOW Foods' CoQ10 in 100 mg has transformed my health. Initially taken for cholesterol, it became a fantastic boost for my heart health. I feel rejuvenated, with a clear mind. My doctor was amazed by the improvement in my cardiovascular system. Additionally, my skin has become soft and smooth.
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 Qunol, Ultra CoQ10, 100 mg, 120 Softgels |
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CoQ10 reduces glioblastoma growth
CoQ reduces glioblastoma growth and infiltration through proteome remodeling and inhibition of angiogenesis and inflammation.
The study focused on understanding how coenzyme Q10 (CoQ) could help manage glioblastoma, a particularly challenging type of brain tumor. We utilized xenograft models with U251 cells implanted in mice to observe tumor growth, inflammation, and vascular changes, alongside assessing the effects of CoQ on various related behaviors, including cell migration and invasion.
We found that CoQ treatment significantly reduced tumor volume in both xenograft and orthotopic models. Interestingly, while it did not directly hinder tumor cell proliferation, it was effective in creating a less hypoxic and vascularized environment. This indicates that CoQ can influence the tumor’s growth dynamics by targeting the underlying conditions that support tumor survival and expansion.
Additionally, CoQ treatment led to a noticeable downregulation of proteins involved in inflammation and angiogenesis, like HIF-1α and NF-kB. This change in molecular activity caused an entire reshaping of the tumor's protein landscape, ultimately impacting how the tumor interacts with its environment. Notably, we observed a restriction in tumor cell migration and invasion, attributed to changes in the cell's structural components.
Overall, our findings suggest that incorporating CoQ into current treatment protocols could provide a holistic approach to combat glioblastoma by simultaneously addressing multiple pathways that facilitate tumor growth and infiltration.
Good for heart and brain
Most Useful Review
1 people found this helpful
The best I've tried so far. The package arrived in good condition, and the ingredients are top quality. This product is truly effective and complete; you can feel the difference from the first dose. I highly recommend it. It aids the heart, brain, and serves as a good antioxidant. The aroma is very light, nothing bothersome.
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 Jarrow Formulas, Q-Absorb, 100 mg, 120 Softgels |
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CoQ10 reduces glioblastoma growth
CoQ reduces glioblastoma growth and infiltration through proteome remodeling and inhibition of angiogenesis and inflammation.
The study focused on understanding how coenzyme Q10 (CoQ) could help manage glioblastoma, a particularly challenging type of brain tumor. We utilized xenograft models with U251 cells implanted in mice to observe tumor growth, inflammation, and vascular changes, alongside assessing the effects of CoQ on various related behaviors, including cell migration and invasion.
We found that CoQ treatment significantly reduced tumor volume in both xenograft and orthotopic models. Interestingly, while it did not directly hinder tumor cell proliferation, it was effective in creating a less hypoxic and vascularized environment. This indicates that CoQ can influence the tumor’s growth dynamics by targeting the underlying conditions that support tumor survival and expansion.
Additionally, CoQ treatment led to a noticeable downregulation of proteins involved in inflammation and angiogenesis, like HIF-1α and NF-kB. This change in molecular activity caused an entire reshaping of the tumor's protein landscape, ultimately impacting how the tumor interacts with its environment. Notably, we observed a restriction in tumor cell migration and invasion, attributed to changes in the cell's structural components.
Overall, our findings suggest that incorporating CoQ into current treatment protocols could provide a holistic approach to combat glioblastoma by simultaneously addressing multiple pathways that facilitate tumor growth and infiltration.
Boosts energy levels
Most Useful Review
I chose this form of CoQ10 because of its quality and beneficial additives that enhance absorbance. I've noticed significant improvements in my energy levels and brain function. While I haven't observed benefits for my skin, topical CoQ10 is renowned for such effects. This fat-soluble antioxidant is crucial for my health.
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 Jarrow Formulas, Vegan Co-Q10, 200 mg, 60 Veggie Capsules |
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CoQ10 reduces glioblastoma growth
CoQ reduces glioblastoma growth and infiltration through proteome remodeling and inhibition of angiogenesis and inflammation.
The study focused on understanding how coenzyme Q10 (CoQ) could help manage glioblastoma, a particularly challenging type of brain tumor. We utilized xenograft models with U251 cells implanted in mice to observe tumor growth, inflammation, and vascular changes, alongside assessing the effects of CoQ on various related behaviors, including cell migration and invasion.
We found that CoQ treatment significantly reduced tumor volume in both xenograft and orthotopic models. Interestingly, while it did not directly hinder tumor cell proliferation, it was effective in creating a less hypoxic and vascularized environment. This indicates that CoQ can influence the tumor’s growth dynamics by targeting the underlying conditions that support tumor survival and expansion.
Additionally, CoQ treatment led to a noticeable downregulation of proteins involved in inflammation and angiogenesis, like HIF-1α and NF-kB. This change in molecular activity caused an entire reshaping of the tumor's protein landscape, ultimately impacting how the tumor interacts with its environment. Notably, we observed a restriction in tumor cell migration and invasion, attributed to changes in the cell's structural components.
Overall, our findings suggest that incorporating CoQ into current treatment protocols could provide a holistic approach to combat glioblastoma by simultaneously addressing multiple pathways that facilitate tumor growth and infiltration.
Noticed improvements
Most Useful Review
5 people found this helpful
Only positive feedback from me. I take Coenzyme Q10 as part of a course. It’s a superb antioxidant. With age, energy production slows, so a supplement like this is necessary. It supports the brain, cardiovascular system, and heart function, and I’ve noticed an increase in energy and mood. There are clear benefits.
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 Himalaya, Organic Ashwagandha, 60 Caplets |
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DHA liposomes show promise
Microfluidic-derived docosahexaenoic acid liposomes for glioblastoma therapy.
We explored an innovative approach to treating glioblastoma, the most common malignant brain tumor, by utilizing docosahexaenoic acid (DHA) liposomes. These liposomes were created using a microfluidic system that allowed for fine-tuning various properties, which could enhance their effectiveness in targeting tumor cells.
Our findings revealed that these DHA liposomes, ranging in size from 80 nm to 130 nm, were successfully taken up by glioblastoma cells. This uptake was promising, as we saw a reduction in the viability of these cancerous cells. Interestingly, we also observed that DHA liposomes were significantly better at triggering cell death mechanisms compared to free DHA, specifically through pathways that involved caspase-3.
Overall, our study suggests that these microfluidic-derived DHA liposomes might offer new avenues for developing therapies using omega-3 fatty acids against brain tumors, potentially leading to more effective treatment options in the future.
Promotes relaxation
Most Useful Review
I found it effective and beneficial in relaxing my brain, and it aids in achieving deep sleep.
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 NOW Foods, Iron, 18 mg, 120 Veg Capsules |
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Iron nanoparticle imaging efficacy
A subtype specific probe for targeted magnetic resonance imaging of M2 tumor-associated macrophages in brain tumors.
We explored the potential of using a specific type of iron nanoparticle to target and image a distinct group of immune cells known as M2 tumor-associated macrophages (TAMs) in brain tumors. These M2 TAMs can promote tumor growth and understanding their behavior could offer insights for better cancer treatments.
In our research, we developed a unique magnetic resonance imaging (MRI) probe composed of ultrafine iron oxide nanoparticles, which are small enough to avoid non-specific action in the body. We included a special peptide that actively seeks out M2 TAMs, allowing us to visualize them more clearly in mouse models of glioblastoma, a common and aggressive type of brain cancer.
The results were promising. The targeted nanoparticles showed a significant increase in accumulation within the tumors compared to standard nanoparticle formulations. This means that the M2-specific MRI probe provided a noticeable contrast in imaging, helping us differentiate areas of interest in the brain tumor environment better than conventional methods.
By demonstrating how effectively these iron nanoparticles can target specific immune cells, our study lays the groundwork for future research surrounding their use in cancer diagnostics and possibly in therapy. This could lead to improved strategies for tracking and altering the tumor environment as cancer progresses.
Itching resolved
Most Useful Review
7 people found this helpful
Recently, even a single hair touching my face made me itchy, which worried me. I discovered that iron deficiency can cause itching and quickly bought this mineral supplement. I adore coffee, but the tannins in it inhibit iron absorption. Initially, I took double the amount of iron, but I learned that too much can harm the digestive tract, liver, heart, and brain, so I reduced my dosage. Since I began taking it, the itching disappeared. I plan to better organise my meals with iron in mind.
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 NOW Foods, Magnesium Malate, 1,000 mg, 180 Tablets |
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Magnesium reduces brain injury markers
Effect of magnesium on functional outcome and paraclinical parameters of patients undergoing supratentorial craniotomy for brain tumors: a randomized controlled trial.
We examined how intravenous magnesium sulfate (MgSO4) affects patients undergoing surgery for brain tumors. Sixty patients were divided into two groups: one received magnesium treatment, while the other received a placebo.
The results showed that magnesium lowered significant protein levels linked to brain injury after surgery. However, it didn’t substantially change the overall functional outcomes for the patients. While MgSO4 appears safe and beneficial in reducing specific markers, more research is necessary to fully grasp magnesium's role in brain injury recovery.
Enhanced concentration
Most Useful Review
8 people found this helpful
This form of magnesium works effectively for me. It does not cause drowsiness. I consume one tablet each morning for four months. The results are evident; my concentration has improved, nervousness has decreased, my unreasonable appetite has vanished, and my headaches have nearly disappeared. I take this medication as advised by a nutritionist. I do not recommend self-prescribing!!!
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 Solgar, Magnesium with Vitamin B6, 250 Tablets |
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Vitamin B6 as glioblastoma target
Vitamin B6 Pathway Maintains Glioblastoma Cell Survival in 3D Spheroid Cultures.
We explored the impact of the vitamin B6 pathway on glioblastoma, a challenging and aggressive brain cancer. Specifically, we assessed how different cell cultures—2D monolayers and 3D spheroids—responded to treatments that alter vitamin B6 levels. Through comprehensive metabolomics analysis, we found notable differences in the levels of vitamin B6-related metabolites between these two culture methods.
Our key finding was that when we used hydralazine, a small molecule known to lower vitamin B6 levels, it induced cell death specifically in the 3D spheroid cultures of glioblastoma. This suggests a potential new therapeutic strategy targeting the vitamin B6 pathway could benefit glioblastoma treatment.
Thus, this study highlights a novel approach to tackle this aggressive cancer by focusing on the metabolic alterations within the tumor microenvironment, particularly through vitamin B6 modulation.
Improves wellbeing
Most Useful Review
Significantly enhances well-being and sleep, with a positive impact on brain function.
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 Doctor's Best, High Absorption Magnesium, 200 mg, 120 Tablets, (100 mg per Tablet) |
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Magnesium reduces brain injury markers
Effect of magnesium on functional outcome and paraclinical parameters of patients undergoing supratentorial craniotomy for brain tumors: a randomized controlled trial.
We examined how intravenous magnesium sulfate (MgSO4) affects patients undergoing surgery for brain tumors. Sixty patients were divided into two groups: one received magnesium treatment, while the other received a placebo.
The results showed that magnesium lowered significant protein levels linked to brain injury after surgery. However, it didn’t substantially change the overall functional outcomes for the patients. While MgSO4 appears safe and beneficial in reducing specific markers, more research is necessary to fully grasp magnesium's role in brain injury recovery.
Hypertension relief
Most Useful Review
52 people found this helpful
After a year of use, my hypertension and related palpitations have disappeared, allowing me to stop medication. Magnesium deficiency seemed to be the cause of my hypertension, and I feel much better since taking this.
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 Source Naturals, Magnesium Malate, 3,750 mg, 360 Tablets (1,250 mg per Tablet) |
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Magnesium reduces brain injury markers
Effect of magnesium on functional outcome and paraclinical parameters of patients undergoing supratentorial craniotomy for brain tumors: a randomized controlled trial.
We examined how intravenous magnesium sulfate (MgSO4) affects patients undergoing surgery for brain tumors. Sixty patients were divided into two groups: one received magnesium treatment, while the other received a placebo.
The results showed that magnesium lowered significant protein levels linked to brain injury after surgery. However, it didn’t substantially change the overall functional outcomes for the patients. While MgSO4 appears safe and beneficial in reducing specific markers, more research is necessary to fully grasp magnesium's role in brain injury recovery.
Improved sleep quality
Most Useful Review
5 people found this helpful
This magnesium malate is excellent value for money. It normalises cell growth, is quickly absorbed, and enhances brain health, alleviating insomnia, headaches, and depression. I typically take it before bed, and it improves both my sleep and overall well-being. Although the jar is secure, it’s kept out of children's reach. I recommend this supplement highly!
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 Life Extension, Neuro-Mag, Magnesium L-Threonate, 144 mg, 90 Vegetarian Capsules (48 mg per Capsule) |
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Magnesium reduces brain injury markers
Effect of magnesium on functional outcome and paraclinical parameters of patients undergoing supratentorial craniotomy for brain tumors: a randomized controlled trial.
We examined how intravenous magnesium sulfate (MgSO4) affects patients undergoing surgery for brain tumors. Sixty patients were divided into two groups: one received magnesium treatment, while the other received a placebo.
The results showed that magnesium lowered significant protein levels linked to brain injury after surgery. However, it didn’t substantially change the overall functional outcomes for the patients. While MgSO4 appears safe and beneficial in reducing specific markers, more research is necessary to fully grasp magnesium's role in brain injury recovery.
Boosts calmness
Most Useful Review
137 people found this helpful
I really liked this form of magnesium. It positively affects brain functioning, enhancing calmness and concentration, leading to better memory quickly.
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 Jarrow Formulas, Vegan MagMind, Brain Health, 144 mg, 90 Veggie Capsules (48 mg per Capsule) |
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Magnesium reduces brain injury markers
Effect of magnesium on functional outcome and paraclinical parameters of patients undergoing supratentorial craniotomy for brain tumors: a randomized controlled trial.
We examined how intravenous magnesium sulfate (MgSO4) affects patients undergoing surgery for brain tumors. Sixty patients were divided into two groups: one received magnesium treatment, while the other received a placebo.
The results showed that magnesium lowered significant protein levels linked to brain injury after surgery. However, it didn’t substantially change the overall functional outcomes for the patients. While MgSO4 appears safe and beneficial in reducing specific markers, more research is necessary to fully grasp magnesium's role in brain injury recovery.
Calms PTSD symptoms
Most Useful Review
6 people found this helpful
My sleep has significantly improved, and as a former addict with PTSD, this supplement positively impacts the addictive part of my brain. It's calming my PTSD and breaking the cycle related to addiction, while also improving my memory.
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 NOW Foods, Glycine, Pure Powder, 1 lb (454 g) |
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Anti-cancer effects of soybean saponins
Triterpenoids from Glycine max decrease invasiveness and induce caspase-mediated cell death in human SNB19 glioma cells.
We explored the impact of soybean-derived compounds, specifically saponins, on human glioblastoma cells. Utilizing a controlled in vitro study, we treated the SNB19 glioma cells with a purified saponin fraction to assess its effects on cell invasiveness and death.
Our findings showed a significant 45% reduction in cell invasion compared to untreated cells, indicating strong anti-invasive properties. Additionally, the treatment triggered apoptosis, as shown by the disruption of mitochondrial function and the activation of key apoptotic markers.
Overall, our study highlights the promising role of these compounds in combating glioblastoma.
Improved mental clarity
Most Useful Review
26 people found this helpful
I am on my third jar of glycine, and it noticeably clears my mind in the morning. As a habitual late sleeper, I struggle to wake up, but after using 1.5-2 grams sublingually, my brain functions much better. This eliminates my tendency towards weakness and dizziness throughout the day, even preventing migraine attacks. Overall, it greatly enhances my mental clarity.
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 Garden of Life, Dr. Formulated Probiotics, Mood+, 60 Vegetarian Capsules |
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DHA liposomes show promise
Microfluidic-derived docosahexaenoic acid liposomes for glioblastoma therapy.
We explored an innovative approach to treating glioblastoma, the most common malignant brain tumor, by utilizing docosahexaenoic acid (DHA) liposomes. These liposomes were created using a microfluidic system that allowed for fine-tuning various properties, which could enhance their effectiveness in targeting tumor cells.
Our findings revealed that these DHA liposomes, ranging in size from 80 nm to 130 nm, were successfully taken up by glioblastoma cells. This uptake was promising, as we saw a reduction in the viability of these cancerous cells. Interestingly, we also observed that DHA liposomes were significantly better at triggering cell death mechanisms compared to free DHA, specifically through pathways that involved caspase-3.
Overall, our study suggests that these microfluidic-derived DHA liposomes might offer new avenues for developing therapies using omega-3 fatty acids against brain tumors, potentially leading to more effective treatment options in the future.
Enhanced relaxation
Most Useful Review
2 people found this helpful
Wonderful probiotic! This excellent product significantly enhances the body and helps one feel more relaxed. It effectively regulates the entire brain.
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 NOW Foods, Folic Acid, 800 mcg, 250 Tablets |
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Folate micelles for tumor diagnosis
Radiolabelled folate micellar carriers as proposed diagnostic aid for CNS tumors by nasal route.
We explored the potential of folate as a diagnostic aid for brain tumors, specifically targeting gliomas—some of the most challenging brain cancers. A key part of our approach involved developing a micellar delivery system that could be given through the nose. This method is less invasive and may provide a more effective way to reach brain tumors.
In our research, we took advantage of the fact that folate receptors are overexpressed in brain tumors, making them an excellent target for diagnosis. We synthesized a folate-conjugated agent, labeled it with technetium (Tc), and encapsulated it within micelles for improved delivery.
Testing revealed that these micelles had a safe profile for nasal administration in rats. In mice, the micelles demonstrated significantly better uptake in the brain compared to a standard folate solution. Imaging studies using specialized techniques showed that these micelles could effectively accumulate in brain tissue.
The findings suggest that this innovative formulation could not only help detect brain tumors but might also be applicable to other cancers that express folate receptors, such as those in the cervical, breast, and lung areas. Overall, we believe our approach has the potential to enhance cancer diagnosis in a fast, accurate, and non-invasive manner.
Essential for development
Most Useful Review
8 people found this helpful
The folic acid dosage is very good. I began taking it in hopes of getting pregnant, and the results were swift, as I conceived in nearly two months. Before taking the pills, it did not work for over seven months. During pregnancy, folic acid is crucial for the development of the child, especially the brain and spinal cord. A deficiency can lead to severe consequences, including potential psychoses or mental retardation in the child.
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 Jarrow Formulas, Vegan BroccoMax, 35 mg, 120 Veggie Capsules |
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Broccoli compound targets brain tumors
d,l-Sulforaphane Induces ROS-Dependent Apoptosis in Human Gliomablastoma Cells by Inactivating STAT3 Signaling Pathway.
We explored how a broccoli compound known as d,l-sulforaphane (SFN) affects glioblastoma cells. Through various tests, we found that SFN can lead to the death of these tumor cells in a timed-response manner. It helps increase harmful substances in the cells while targeting specific signaling pathways—particularly the STAT3 pathway.
Although our study shows SFN has potential in fighting brain tumors, we acknowledge that more research is needed to fully understand and confirm its effectiveness in clinical settings.
Tumour-free belief
Most Useful Review
23 people found this helpful
I was diagnosed with bladder cancer in 2016. My doctor suggested broccoli as a superfood to help combat cancer. Although I dislike broccoli, BroccoMax contains the necessary sulforaphane. I've taken it daily since October 2017 and believe this quality product, along with lifestyle changes, has kept me tumour-free.
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 Solgar, Vitamin B6, 25 mg, 100 Tablets |
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Vitamin B6 as glioblastoma target
Vitamin B6 Pathway Maintains Glioblastoma Cell Survival in 3D Spheroid Cultures.
We explored the impact of the vitamin B6 pathway on glioblastoma, a challenging and aggressive brain cancer. Specifically, we assessed how different cell cultures—2D monolayers and 3D spheroids—responded to treatments that alter vitamin B6 levels. Through comprehensive metabolomics analysis, we found notable differences in the levels of vitamin B6-related metabolites between these two culture methods.
Our key finding was that when we used hydralazine, a small molecule known to lower vitamin B6 levels, it induced cell death specifically in the 3D spheroid cultures of glioblastoma. This suggests a potential new therapeutic strategy targeting the vitamin B6 pathway could benefit glioblastoma treatment.
Thus, this study highlights a novel approach to tackle this aggressive cancer by focusing on the metabolic alterations within the tumor microenvironment, particularly through vitamin B6 modulation.
Well tolerated supplement
Most Useful Review
5 people found this helpful
I ordered Vitamin B6 alongside Magnesium. The tablets are small and easy to swallow, well tolerated by my body. It effectively enhances brain performance, as well as memory and mood.
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 NOW Foods, P-5-P, 50 mg, 90 Veg Capsules |
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Vitamin B6 as glioblastoma target
Vitamin B6 Pathway Maintains Glioblastoma Cell Survival in 3D Spheroid Cultures.
We explored the impact of the vitamin B6 pathway on glioblastoma, a challenging and aggressive brain cancer. Specifically, we assessed how different cell cultures—2D monolayers and 3D spheroids—responded to treatments that alter vitamin B6 levels. Through comprehensive metabolomics analysis, we found notable differences in the levels of vitamin B6-related metabolites between these two culture methods.
Our key finding was that when we used hydralazine, a small molecule known to lower vitamin B6 levels, it induced cell death specifically in the 3D spheroid cultures of glioblastoma. This suggests a potential new therapeutic strategy targeting the vitamin B6 pathway could benefit glioblastoma treatment.
Thus, this study highlights a novel approach to tackle this aggressive cancer by focusing on the metabolic alterations within the tumor microenvironment, particularly through vitamin B6 modulation.
Supports cognitive function
Most Useful Review
1 people found this helpful
This vitamin works wonders for cognition. The P5P vitamin B6 contains quality ingredients and comes in small capsules, making it easy to take. It supports the nervous system and effectively meets the brain's needs when combined with other supplements. I wholeheartedly recommend it!
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 NOW Foods, Glutathione, 500 mg, 60 Veg Capsules |
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Silibinin shows toxicity via EGFR
Epidermal growth factor receptor mediates silibinin-induced cytotoxicity in a rat glioma cell line.
We explored how silibinin, a compound from milk thistle, impacts brain tumor cells by focusing on the epidermal growth factor receptor (EGFR). In our study, we created a specific rat glioma cell line expressing human EGFR. Our results showed that the presence of EGFR was crucial for silibinin to exert its toxic effects on cancer cells. By inhibiting the activation of EGFR, silibinin demonstrates potential as a therapeutic agent for targeting tumor growth. However, further research is needed to understand the detailed mechanisms at play.
Significant improvement
Most Useful Review
512 people found this helpful
I rated it 5. I administered it to my teenage daughter, one at a time, for a significant period. I used it to restore brain function! The results have been astonishing, literally! Numerous issues have been markedly corrected, including severe fears, impaired attention, memory, and depression. Cognitive functions have improved significantly. Now Foods offer effective and affordable products, so I highly recommend it to anyone looking to enhance brain function! Best of luck to you!
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 NOW Foods, DHA-1000 Brain Support, Extra Strength, 1,000 mg, 90 Softgels |
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DHA inhibits glioma stem cells
Dihydroartemisinin exhibits anti-glioma stem cell activity through inhibiting p-AKT and activating caspase-3.
We explored the potential of dihydroartemisinin (DHA), a compound derived from an antimalarial drug, to impact glioma stem cells (GSCs). In our study, we found that DHA effectively halted the growth of GSCs and triggered their programmed cell death.
We discovered that DHA influenced the activation of specific proteins that control these processes. In particular, it reduced the activity of p-AKT while boosting Cleaved Caspase-3 levels.
These findings suggest that DHA could offer a promising new method for treating challenging brain tumors like gliomas.
Improved memory
Most Useful Review
4 people found this helpful
Very effective! I experienced clarity and improved memory. By the second day, my brain felt much more active, and my speech was noticeably faster. I truly enjoy this product!
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 Sports Research, Omega-3 Fish Oil, Triple Strength , 30 Softgels |
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DHA liposomes show promise
Microfluidic-derived docosahexaenoic acid liposomes for glioblastoma therapy.
We explored an innovative approach to treating glioblastoma, the most common malignant brain tumor, by utilizing docosahexaenoic acid (DHA) liposomes. These liposomes were created using a microfluidic system that allowed for fine-tuning various properties, which could enhance their effectiveness in targeting tumor cells.
Our findings revealed that these DHA liposomes, ranging in size from 80 nm to 130 nm, were successfully taken up by glioblastoma cells. This uptake was promising, as we saw a reduction in the viability of these cancerous cells. Interestingly, we also observed that DHA liposomes were significantly better at triggering cell death mechanisms compared to free DHA, specifically through pathways that involved caspase-3.
Overall, our study suggests that these microfluidic-derived DHA liposomes might offer new avenues for developing therapies using omega-3 fatty acids against brain tumors, potentially leading to more effective treatment options in the future.
Visible health results
Most Useful Review
1 people found this helpful
This Omega-3 is truly remarkable! It boasts the best price-quality ratio and efficacy. A single capsule provides a daily dose, avoiding the need for multiple intakes—which I occasionally forget. I’ve purchased it for myself and my elderly parents. Notably, I have witnessed improvements in skin and hair, and these Omega-3 fatty acids are essential for our brain, enhancing memory and cognitive function significantly. I wholeheartedly recommend it!
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 NOW Foods, Sunflower Lecithin, 1,200 mg, 200 Softgels |
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Curcumin nanosuspensions show promise
High drug payload curcumin nanosuspensions stabilized by mPEG-DSPE and SPC: in vitro and in vivo evaluation.
We focused on enhancing the delivery of curcumin, a drug known for its anti-cancer properties yet limited by poor solubility. Our study developed curcumin nanosuspensions using a stabilizer blend of mPEG2000-DSPE and soybean lecithin, aimed at improving its solubility and overall effectiveness against tumors.
The resulting formulation showed a substantial drug uptake and improved therapeutic efficacy, outperforming traditional curcumin injections in both cytotoxicity and distribution in vital organs, including the brain and tumors. Overall, these findings indicate a promising future for curcumin as a cancer treatment.
Vital nutrient
Most Useful Review
139 people found this helpful
Lecithin is a crucial nutrient for strengthening the brain and nervous system. It plays a role in forming cell membranes and is essential for the myelin sheath of nerve fibres! It's an excellent supplement; I began with one capsule a day and, later on, increased it to two, realising its effects! Used alongside Alpha-lipoic acid, vitamin D3, Curcumin, and vitamin B6, I've felt revived from 8 in the morning. I've become more productive at work, reading much more efficiently (with less memory lapse of around 30%), and even my boss has noticed I've been less forgetful regarding small things like keys or documents. This lecithin has become an essential supplement for me.
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 NOW Foods, Alpha Lipoic Acid, 100 mg, 120 Veg Capsules |
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Vitamin C impacts glioblastoma progression
Vitamin C deficient reduces proliferation in a human periventricular tumor stem cell-derived glioblastoma model.
We aimed to understand how a lack of vitamin C influences the growth of glioblastoma, one of the most aggressive types of brain tumors. Using guinea pigs, we tested the effects of a vitamin C-deficient diet on tumor growth caused by two different human glioblastoma cell lines, U87-MG and HSVT-C3.
Through this study, we observed that the absence of vitamin C significantly hindered tumor proliferation in both models. Notably, we found that vitamin C deficiency reduced factors associated with tumor growth, such as vasculature and immune cell infiltration, particularly in the HSVT-C3 cells, which are known for their stem cell-like properties.
Our findings suggest that vitamin C plays a crucial role in supporting tumor growth, and when absent, it can lead to a notable reduction in glioblastoma progression. This emphasizes the potential importance of maintaining adequate vitamin C levels for patient outcomes in brain tumor scenarios.
Boosts brain function
Most Useful Review
I purchased lipoic acid due to positive reviews. It provides multiple benefits such as increased energy, enhanced immune function, improved memory and brain performance, better vision, and supports liver recovery. It aids weight loss, normalises blood pressure, detoxifies, and lowers cholesterol and blood sugar. The quality is high, the capsules are of standard size and neutral in taste. I recommend it for prolonging youth!
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 Doctor's Best, Alpha-Lipoic Acid 600, 600 mg, 180 Veggie Caps |
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Alleviated fog
Most Useful Review
4 people found this helpful
Excellent for mental clarity! It has significantly helped with my brain fog.
Value for money
Most Useful Review
3 people found this helpful
With 60 capsules per bottle, this offers great value. Alpha lipoic acid enhances cognitive function and brain health, improving concentration and memory. The product is in a vegetable capsule, making it suitable for various diets. I have been consistently taking it due to its positive effects.
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 Life Extension, Sea-Iodine, 1,000 mcg, 60 Vegetarian Capsules |
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Fucoidan shows potential bioactivity
Influence of molecular weight fractionation on the antimicrobial and anticancer properties of a fucoidan rich-extract from the macroalgae Fucus vesiculosus.
We explored the antimicrobial and anticancer properties of a fucoidan extract derived from the macroalgae Fucus vesiculosus. This study involved testing various fractions of the extract against bacterial strains and brain glioblastoma cancer cells.
The results showed that the larger fractions (>300 kDa) displayed the most significant cytotoxic effects on the cancer cells over time. While the study confirmed the potential of this extract as an antimicrobial and anticancer agent, further research is necessary to uncover the exact mechanisms behind its effects.
Memory clarity restored
Most Useful Review
I appreciated the effect on stabilising my brain activity. After suffering from memory issues post-COVID, this iodine helped restore my clarity and alleviated my forgetfulness.
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 NOW Foods, Certified Organic Inulin, Prebiotic Pure Powder, 8 oz (227 g) |
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Bradykinin enhances tumor permeability
Bradykinin selectively opens blood-tumor barrier in experimental brain tumors.
We investigated the effects of bradykinin on the permeability of tumor capillaries to various substances, including inulin, in a model of RG2 glioma in rats. In this study, bradykinin was administered through the carotid artery to see how it would alter the capillary barrier in brain tumors.
Our findings revealed that bradykinin significantly increased the permeability of tumor vessels to several tracers, including inulin. Specifically, the permeability for inulin was 23.92, compared to just 6.20 in the control group receiving saline. This indicates that bradykinin may play a role in enhancing the ability of substances like inulin to penetrate brain tumors, which could have implications for drug delivery in such conditions.
It's important to note that the permeability changes observed were limited to the tumor sites and did not affect normal brain tissue. Moreover, once the bradykinin infusion was stopped, the increased permeability returned to baseline levels within 20 minutes, emphasizing the temporary nature of its effect. Overall, our research highlights the potential for using bradykinin to improve the delivery of treatments for brain tumors by temporarily opening up the blood-tumor barrier.
Gut-brain connection
Most Useful Review
7 people found this helpful
Inulin works wonderfully! We’ve given up probiotics to focus solely on prebiotics, and it has profoundly impacted my life and my children’s. It’s crucial to nourish the existing good bacteria rather than continuously introducing new strains. I've seen improvements in my daughter's concentration and a decrease in her aggressiveness. A healthy gut promotes a healthy brain—this prebiotic is a fantastic choice!
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 Nature's Way, Cell Forté, IP-6 & Inositol, 240 Vegan Capsules |
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INPP5E's impact on medulloblastoma
A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma.
We examined how INPP5E influences Sonic Hedgehog (SHH) signaling in medulloblastoma, a common pediatric brain tumor. By using a murine model, we found that deleting INPP5E reduced tumor growth, cell proliferation, and SHH signaling while causing a loss of cilia on tumor cells.
Our findings suggest that INPP5E is crucial for maintaining primary cilia and promoting tumor progression. Interestingly, we observed that lower levels of INPP5E in human samples correlated with better survival outcomes, highlighting its potential as a therapeutic target in combating SHH medulloblastoma.
Negative experience
Most Useful Review
15 people found this helpful
Bad product. I felt an increase in energy and digestion initially, but after that, I experienced strange tingling and sharp pain in my stomach, along with insomnia. Even after I stopped using this product, I sleep poorly, as if my brain is blocked from resting. Initially, I thought the symptoms might be typical die-off, but they were far worse than any I have experienced before. Even activated charcoal, which helped previously, did not work here.
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 NOW Foods, Inositol Capsules, 500 mg, 100 Veg Capsules |
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INPP5E's impact on medulloblastoma
A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma.
We examined how INPP5E influences Sonic Hedgehog (SHH) signaling in medulloblastoma, a common pediatric brain tumor. By using a murine model, we found that deleting INPP5E reduced tumor growth, cell proliferation, and SHH signaling while causing a loss of cilia on tumor cells.
Our findings suggest that INPP5E is crucial for maintaining primary cilia and promoting tumor progression. Interestingly, we observed that lower levels of INPP5E in human samples correlated with better survival outcomes, highlighting its potential as a therapeutic target in combating SHH medulloblastoma.
Calms nerves effectively
Most Useful Review
77 people found this helpful
Inositol is beneficial for brain circuits and the nervous system. It effectively treats sleep disorders at dosages between 500 to 1500 mg daily. I noticed a significant reduction in nervousness after using it for a couple of weeks. It’s also helpful for calming children who may be restless or anxious.
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 Jarrow Formulas, Vegan IP6, 120 Veggie Capsules |
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INPP5E's impact on medulloblastoma
A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma.
We examined how INPP5E influences Sonic Hedgehog (SHH) signaling in medulloblastoma, a common pediatric brain tumor. By using a murine model, we found that deleting INPP5E reduced tumor growth, cell proliferation, and SHH signaling while causing a loss of cilia on tumor cells.
Our findings suggest that INPP5E is crucial for maintaining primary cilia and promoting tumor progression. Interestingly, we observed that lower levels of INPP5E in human samples correlated with better survival outcomes, highlighting its potential as a therapeutic target in combating SHH medulloblastoma.
Speedy delivery service
Most Useful Review
4 people found this helpful
I ordered Jarrow Formulas IP6, and the immediate delivery impressed me. The capsules help chelate and remove the iron accumulation in my brain due to CCSVI, and I believe they are making a difference. I'm extremely happy with both the effectiveness and the swift service provided.
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 NOW Foods, Choline & Inositol, 100 Veg Capsules |
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INPP5E's impact on medulloblastoma
A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma.
We examined how INPP5E influences Sonic Hedgehog (SHH) signaling in medulloblastoma, a common pediatric brain tumor. By using a murine model, we found that deleting INPP5E reduced tumor growth, cell proliferation, and SHH signaling while causing a loss of cilia on tumor cells.
Our findings suggest that INPP5E is crucial for maintaining primary cilia and promoting tumor progression. Interestingly, we observed that lower levels of INPP5E in human samples correlated with better survival outcomes, highlighting its potential as a therapeutic target in combating SHH medulloblastoma.
Reduced headaches
Most Useful Review
224 people found this helpful
This supplement aids in the correct transmission of nerve impulses in the body. Choline and inositol are essential B vitamins necessary for brain, nervous system health, and fatty acid metabolism. I combine these with True Calm and have found noticeable relaxation, with almost no daily headaches. My mind remains clear until evening, which greatly enhances my concentration and overall performance.
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 Solgar, Choline/Inositol, 100 Vegetable Capsules |
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INPP5E's impact on medulloblastoma
A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma.
We examined how INPP5E influences Sonic Hedgehog (SHH) signaling in medulloblastoma, a common pediatric brain tumor. By using a murine model, we found that deleting INPP5E reduced tumor growth, cell proliferation, and SHH signaling while causing a loss of cilia on tumor cells.
Our findings suggest that INPP5E is crucial for maintaining primary cilia and promoting tumor progression. Interestingly, we observed that lower levels of INPP5E in human samples correlated with better survival outcomes, highlighting its potential as a therapeutic target in combating SHH medulloblastoma.
Lowered stress levels
Most Useful Review
1 people found this helpful
Solgar Choline/Inositol is a great supplement that supports healthy brain, nervous system, and metabolic function. After using it, I’ve experienced improvements in my memory, concentration, and reduced stress. The capsules are easy to swallow and well tolerated.
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 NOW Foods, Green Tea Extract, 400 mg, 250 Veg Capsules |
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Vitamin C impacts glioblastoma progression
Vitamin C deficient reduces proliferation in a human periventricular tumor stem cell-derived glioblastoma model.
We aimed to understand how a lack of vitamin C influences the growth of glioblastoma, one of the most aggressive types of brain tumors. Using guinea pigs, we tested the effects of a vitamin C-deficient diet on tumor growth caused by two different human glioblastoma cell lines, U87-MG and HSVT-C3.
Through this study, we observed that the absence of vitamin C significantly hindered tumor proliferation in both models. Notably, we found that vitamin C deficiency reduced factors associated with tumor growth, such as vasculature and immune cell infiltration, particularly in the HSVT-C3 cells, which are known for their stem cell-like properties.
Our findings suggest that vitamin C plays a crucial role in supporting tumor growth, and when absent, it can lead to a notable reduction in glioblastoma progression. This emphasizes the potential importance of maintaining adequate vitamin C levels for patient outcomes in brain tumor scenarios.
Protects brain cells
Most Useful Review
Green tea is known to support cognition, aid in maintaining moderate weight, and protect against cellular damage. Its functional components may enhance brain function and cognitive health, thereby decreasing the risk of cognitive impairment in midlife and older adults. I wholeheartedly endorse it; I've been taking 1000mg daily for years.
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 Life Extension, Super Omega-3, EPA/DHA Fish Oil, Sesame Lignans & Olive Extract, 60 Enteric Coated Softgels |
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Omega-3 fatty acids induce cell death
ω3-polyunsaturated fatty acids induce cell death through apoptosis and autophagy in glioblastoma cells: In vitro and in vivo.
We delved into the potential of omega-3 polyunsaturated fatty acids, specifically docosahexaenoic acid (DHA), to combat glioblastoma, one of the most aggressive brain tumors.
In our study, we found that DHA treatment led to cell death in glioblastoma cells, as evidenced by signs of apoptosis and increased autophagy. Furthermore, tests in transgenic mice revealed a notable reduction in tumor size and increased activity reflected in cell death markers.
While these findings suggest a promising avenue for GBM treatment, further research is needed to fully understand how omega-3 fatty acids could be integrated into cancer therapies.
Improved brain function
Most Useful Review
My experience with Life Extension Advanced Omega-3 has been excellent. After using it, I noticed a clear improvement in my cardiovascular health, with stabilized blood pressure and lipid levels. My brain feels clearer, and I've seen enhancements in my concentration and memory. I highly recommend it for anyone concerned about brain function and cardiovascular health.
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 Doctor's Best, Purified & Clear Omega 3 Fish Oil, 2,000 mg, 120 Marine Softgels (1,000 mg per Softgel) |
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Omega-3 fatty acids induce cell death
ω3-polyunsaturated fatty acids induce cell death through apoptosis and autophagy in glioblastoma cells: In vitro and in vivo.
We delved into the potential of omega-3 polyunsaturated fatty acids, specifically docosahexaenoic acid (DHA), to combat glioblastoma, one of the most aggressive brain tumors.
In our study, we found that DHA treatment led to cell death in glioblastoma cells, as evidenced by signs of apoptosis and increased autophagy. Furthermore, tests in transgenic mice revealed a notable reduction in tumor size and increased activity reflected in cell death markers.
While these findings suggest a promising avenue for GBM treatment, further research is needed to fully understand how omega-3 fatty acids could be integrated into cancer therapies.
Improved memory noted
Most Useful Review
I deem the adoption of this vitamin essential for everyone, as it positively influences cardiovascular activity, slows thrombus formation, maintains immunity, and normalises blood circulation in the brain. After completing the course, I observed improved memory and more hydrated skin. Omega-3 also aids in cholesterol elimination.
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 Solgar, Omega 3, EPA & DHA, Triple Strength, 950 mg, 100 Softgels |
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Omega-3 fatty acids induce cell death
ω3-polyunsaturated fatty acids induce cell death through apoptosis and autophagy in glioblastoma cells: In vitro and in vivo.
We delved into the potential of omega-3 polyunsaturated fatty acids, specifically docosahexaenoic acid (DHA), to combat glioblastoma, one of the most aggressive brain tumors.
In our study, we found that DHA treatment led to cell death in glioblastoma cells, as evidenced by signs of apoptosis and increased autophagy. Furthermore, tests in transgenic mice revealed a notable reduction in tumor size and increased activity reflected in cell death markers.
While these findings suggest a promising avenue for GBM treatment, further research is needed to fully understand how omega-3 fatty acids could be integrated into cancer therapies.
Promotes brain development
Most Useful Review
2 people found this helpful
The price-performance ratio of Omega 3 is excellent. I took just one tablet daily during my pregnancy, resulting in fantastic skin and hair condition without any stretch marks, and my child was born healthy and smart. Omega-3 aids in the establishment and development of the brain in utero. I highly recommend it for mothers!
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 NOW Foods, Ultra Omega 3-D, 600 EPA / 300 DHA, 90 Fish Softgels |
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Omega-3 fatty acids induce cell death
ω3-polyunsaturated fatty acids induce cell death through apoptosis and autophagy in glioblastoma cells: In vitro and in vivo.
We delved into the potential of omega-3 polyunsaturated fatty acids, specifically docosahexaenoic acid (DHA), to combat glioblastoma, one of the most aggressive brain tumors.
In our study, we found that DHA treatment led to cell death in glioblastoma cells, as evidenced by signs of apoptosis and increased autophagy. Furthermore, tests in transgenic mice revealed a notable reduction in tumor size and increased activity reflected in cell death markers.
While these findings suggest a promising avenue for GBM treatment, further research is needed to fully understand how omega-3 fatty acids could be integrated into cancer therapies.
Wonderful supplement
Most Useful Review
1 people found this helpful
Excellent! A wonderful supplement for the brain!
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 Solgar, Sublingual Methylcobalamin (Vitamin B12), 5,000 mcg, 30 Nuggets |
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Vitamin B12's unclear impact on glioblastoma
Effect of pyridoxine or cobalamin supplementation on apoptosis and cell cycle progression in a human glioblastoma cell line.
We explored the effects of vitamin B12 (cobalamin) supplementation on a human glioblastoma cell line known as U-87 MG. Our main goal was to understand how cobalamin, particularly in combination with pyridoxine (vitamin B6), influences cell viability and the process of cell death, known as apoptosis.
Our approach involved treating the glioblastoma cells with varying concentrations of vitamin B12 over a period of 24 to 72 hours. We assessed the health of the cells and their progression through the cell cycle using methods like spectrophotometry and flow cytometry. We also measured specific proteins associated with cell survival and death through western blot analysis.
We found that while vitamin B6 supplementation led to decreased cell viability and increased signs of apoptosis, the role of vitamin B12 was less clear. It appeared that cobalamin did not significantly enhance or inhibit cell death on its own. However, when combined with pyridoxine, it seemed to reduce the cytotoxic effects of vitamin B6.
In summary, while vitamin B12 in isolation did not show a direct benefit for the glioblastoma cells in our study, its potential to influence the effects of other vitamins highlights a complex interaction deserving of further exploration.
Clarity and energy
Most Useful Review
Excellent. The best brand I have tried. This is the most effective brand thus far. I have tried numerous brands that simply do not work. This and Jarrow work exceptionally well, but this one truly stands out. It provides clarity and instant energy for my mind. Remarkable for overcoming physical and mental fatigue as well as brain fog. Although I am not keen on the inclusion of mannitol, I can overlook that.
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 Solgar, Methylcobalamin (Vitamin B12), 1,000 mcg, 60 Nuggets |
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Vitamin B12's unclear impact on glioblastoma
Effect of pyridoxine or cobalamin supplementation on apoptosis and cell cycle progression in a human glioblastoma cell line.
We explored the effects of vitamin B12 (cobalamin) supplementation on a human glioblastoma cell line known as U-87 MG. Our main goal was to understand how cobalamin, particularly in combination with pyridoxine (vitamin B6), influences cell viability and the process of cell death, known as apoptosis.
Our approach involved treating the glioblastoma cells with varying concentrations of vitamin B12 over a period of 24 to 72 hours. We assessed the health of the cells and their progression through the cell cycle using methods like spectrophotometry and flow cytometry. We also measured specific proteins associated with cell survival and death through western blot analysis.
We found that while vitamin B6 supplementation led to decreased cell viability and increased signs of apoptosis, the role of vitamin B12 was less clear. It appeared that cobalamin did not significantly enhance or inhibit cell death on its own. However, when combined with pyridoxine, it seemed to reduce the cytotoxic effects of vitamin B6.
In summary, while vitamin B12 in isolation did not show a direct benefit for the glioblastoma cells in our study, its potential to influence the effects of other vitamins highlights a complex interaction deserving of further exploration.
Energising recovery
Most Useful Review
33 people found this helpful
Miraculously, after trying various brands without success for stress relief and brain recovery, this product proved transformative. Immediate effects were evident once I resumed taking the sweet pink tablet; I was very sleepy, which seemed necessary for my recovery. A weekend of rest led to a refreshing revitalisation thereafter. I'm continually impressed by the high quality of Solgar products compared to others.
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 NOW Foods, Cat's Claw, 500 mg, 250 Veg Capsules |
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Saved my mother
Most Useful Review
96 people found this helpful
This Cat's Claw is economical and a top choice. It’s arguably one of the best, yet many people are unaware of its effectiveness. It saved my mother from the damaging effects of her brain tumour and has helped us through flu epidemics, digestive issues, and even improved skin appearance. It's essential to have at home!
Benign tumour removal
Most Useful Review
29 people found this helpful
Cat's claw has assisted my friend in eliminating two benign tumours on her thyroid gland after five months of use. I ordered it for my aunt, who has three similar conditions. We're awaiting delivery, and I will report back on results in a year and a half. There is always hope! Wishing everyone good health and no ill fortune!
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 NOW Foods, Nattokinase, 100 mg, 120 Veg Capsules |
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Headache relief achieved
Most Useful Review
10 people found this helpful
A wonder drug! A doctor recommended it to help with micro clots. Since starting this treatment, my headaches have stopped, brain fog has decreased, and my physical activity has increased. Beware, it may cause an initial worsening of symptoms. After that, it’s fantastic!
Significant health improvements
Most Useful Review
1 people found this helpful
This medication is truly remarkable! A doctor recommended it for my micro clots and I’ve noticed significant improvements. My headaches have vanished, brain fog has lessened, and my physical activity has increased. It can cause a Herx reaction initially, worsening symptoms temporarily, but after that, it works wonders. Taste isn’t an issue, and I find its quality comparable to other medications I've tried.
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 Doctor's Best, High Potency Serrapeptase, 120,000 SPU, 270 Veggie Caps |
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Inflammation alleviated
Most Useful Review
28 people found this helpful
My father takes Doctor's Best High Potency Serrapeptase and has experienced remarkable improvement seven months after major surgery. It has effectively reduced inflammation, and he reports that it cleared up the brain fog he was experiencing. After one month on serrapeptase, he feels alert and energetic again.
Tremors disappeared
Most Useful Review
12 people found this helpful
I have used Dr's Best Serrapeptase for many years. After sustaining a head injury at work, I experienced persistent headaches and tremors in my left hand. After taking serrapeptase for two years, my tremors vanished. I had traces of blood in my brain and was under a neurologist's supervision at the time. Thankfully, I have had no further complications since then, thanks to serrapeptase and prayer.
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 Solgar, Omega 3-6-9, 1,300 mg, 120 Softgels |
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Support for children
Most Useful Review
2 people found this helpful
Omega 3-6-9 is an excellent fatty acid complex, recommended for my child by a neurologist. It positively affects brain development and visual cells, serves as a valuable building block for nerve cells, and reduces hyperactivity. Our family takes this complex, and I highly recommend it.
Improved well-being
Most Useful Review
Solgar Omega 3-6-9 is an excellent dietary supplement that has become essential in my health routine. As a health-conscious individual, I am impressed with the quality and effectiveness of this product. Its unique formula boasts a balanced blend of essential fatty acids—omega-3, omega-6, and omega-9—which are vital for brain function and overall health. Since taking Solgar Omega 3-6-9, I have noticed significant improvements in my energy levels, mood stability, and skin vitality. My cardiovascular health has also improved, with better cholesterol levels. The softgels are convenient to swallow and have no unpleasant taste. I highly recommend Solgar Omega 3-6-9 for anyone seeking effective health support.
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 NOW Foods, ADAM, Superior Men's Multi, 90 Softgels |
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Enhances male health
Most Useful Review
2 people found this helpful
NOW® ADAM ™ Vitamins for Men offer concentrated essential nutrients that maximise intake for male health. The composition includes Veg. beta-carotene, potent B vitamins, and ZMA®. Notably, they enhance brain function and support the cardiovascular system, promoting general wellbeing. These vitamins are highly recommended for any man planning for conception and significantly strengthen the reproductive system.
Comprehensive health benefits
Most Useful Review
These vitamins provide significant health benefits, including tonic effects for energy, strong immunostimulating properties, and support for heart activity. They also improve brain functionality, suppress inflammation, and enhance the health of men's reproductive systems. Overall, a thorough formulation catering to diverse health needs.
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 Navitas Organics, Organic Superfood+® Adaptogen Blend, 6.3 oz (180 g) |
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Enhanced mental clarity
Most Useful Review
2 people found this helpful
Mixed with milk, it has kept me feeling good all day; my brain fog has vanished, and my mind feels clear. The results were unexpected, prompting me to repurchase the stock immediately.
Supports brain health
Most Useful Review
This product is fantastic for the immune system and overall health. It contains three beneficial adaptogens: maca, reishi mushroom, and ashwagandha, which are exceptional for brain health and mental well-being.
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 NOW Foods, Krill Oil, 500 mg, 120 Softgels |
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Feeds the brain
Most Useful Review
2 people found this helpful
Brain food! I am so grateful for this wonderful food that nourishes my brain, soothes inflammation, and is easy to digest. I bought it on a whim, expecting it to be good, and it works just as well as the more expensive brands at half the price. Shipping is affordable, especially living across the Pacific, and the time taken was excellent. Thank you, iHerb, for helping us live healthier!
Eliminates brain fog
Most Useful Review
NOW makes quality products. This Krill Oil is superb for the brain; it has eliminated my brain fog. Though it's pricey, it is worth every penny. Truly the best!
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 Carlson, Cod Liver Oil, Natural Green Apple , 1,100 mg, 8.4 fl oz (250 ml) |
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Enhances immunity
Most Useful Review
Super! This omega supplement is fantastic. It supports brain function and boosts immunity—everything is excellent! I genuinely enjoyed it.
Supports brain development
Most Useful Review
This product is of the highest quality and free from heavy metals, making it safe for children at half the adult dose. It plays a crucial role in their brain development.
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 Garden of Life, Dr. Formulated Brain Health, 100% Organic Coconut MCT Oil, Unflavored, 13 g, 32 fl oz (946 ml) |
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Boosts energy quickly
Most Useful Review
3 people found this helpful
Good day everyone! This isn't my first order of this oil, and I could sing an ode to it! MCT oil, unlike other fats, doesn't settle as fat; it quickly enters the liver and transforms into energy. MCT fatty acids speed up metabolism, assist in weight management, energise the brain, and enhance efficiency. I take a tablespoon of it each day on an empty stomach!
Focus and clarity
Most Useful Review
2 people found this helpful
I absolutely adore the Garden of Life Dr. Formulated Brain Health Coconut MCT Oil! This unflavoured oil has become an essential part of my daily routine, providing sustainable energy that keeps me focused and mentally sharp. Knowing it’s 100% organic reassures me about my intake. Whether it’s added to my coffee or cooking, the benefits are clear. For anyone seeking a natural method to enhance brain health, this MCT oil is a must-try!
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 Natrol, Melatonin, Fast Dissolve, Maximum Strength, Citrus, 10 mg, 100 Tablets |
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Improved sleep quality
Most Useful Review
1 people found this helpful
Works perfectly for me. Exactly what I needed. The flavour is decent and does not taste of chemicals. I take the tablet, read my book for 15-20 minutes, and then enjoy an amazing night’s sleep. I am not groggy in the morning. I had to train my body for a new sleeping schedule in a new location. These tablets were instrumental in transforming my restless nights and training my brain to feel sleepy in that environment. I would highly recommend.
Significantly aids sleep
Most Useful Review
1 people found this helpful
A-M-A-Z-I-N-G! The only product that assists my insomniac brain in achieving sleep.
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 Natrol, Melatonin, 3 mg, 60 Tablets |
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Good investment
Most Useful Review
1 people found this helpful
Great product with excellent quality! A can of 240 3mg tablets lasts nearly a year, making it a worthwhile investment. It helps me achieve deeper sleep, though I do feel a bit sedated the following day. I found out it's best to take melatonin a couple of hours before bed, as the brain releases natural melatonin earlier than expected.
Restores biological clock
Most Useful Review
Melatonin is a highly effective supplement for those with disrupted sleep cycles due to late jobs or insomnia. It aids in restoring the biological clock of sleep and wake cycles by delivering melatonin to brain cells.
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 21st Century, Extra Strength, Quick Dissolve Melatonin, Cherry, 10 mg, 360 Tablets |
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Enhanced alertness
Most Useful Review
3 people found this helpful
Best for me! I’ve been using these melatonin tablets for a few weeks and absolutely love them. They work quickly, in less than 20 minutes, and I’m asleep. One small tablet is easy to swallow and has a great taste. I will continue to purchase them; shipping to Romania takes about two weeks. The aroma is delightful and not overly sweet. I feel revitalised and more alert, the brain fog has disappeared. I enjoy restful nights and wake up headache-free.
Brain protection
Most Useful Review
Excellent product! The composition is truly effective! I purchased it for my mother to help protect her brain.
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 Solgar, Melatonin, 10 mg, 60 Tablets |
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Improved sleep quality
Most Useful Review
3 people found this helpful
After a complex brain surgery ten years ago, my mother struggled with sleep, only managing three to four hours nightly. This led to constant fatigue and depression. She was reluctant to rely on strong sleeping pills, and natural alternatives offered little relief. We decided to try melatonin, purchasing 10 mg. Remarkably, it helped alleviate her long-standing insomnia! Now, before bedtime, she takes one pill and sleeps for six to seven hours. Mum is delighted; her sleep has returned to normal, and her mood and well-being have significantly improved.
Regular sleep routine
Most Useful Review
1 people found this helpful
These small tablets are easy to swallow and have helped my son and me both to fall asleep and stay asleep. My son, who has ADHD, and I often struggle to produce sufficient melatonin for sleep. Within 30 minutes of taking the tablet, we are ready for bed. My son, who is 16, began using these tablets three months ago and has thanked me for this product, as he used to stay awake until 2 or 3 am. Now, he has established a regular sleep routine and understands that it’s due to taking this 10 mg dosage of Solgar melatonin nightly. We awaken refreshed with no grogginess, and I will continue purchasing this fantastic product.
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 NOW Foods, Selenium, 200 mcg, 180 Veg Capsules |
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Health maintenance
Most Useful Review
136 people found this helpful
Selenium is an indispensable supplement for cancer prevention. If you wish to maintain your health and reduce the risk of tumours, then this supplement is essential.
Anti-tumour effect
Most Useful Review
33 people found this helpful
Great selenium! It is an absolutely essential trace element vital for all our organs. Without it, iodine cannot be absorbed. It is crucial for men's health and possesses excellent anti-tumour properties. This is a basic supplement I recommend for my family and I will surely reorder. Stay healthy!
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 Country Life, Selenium, 100 mcg, 180 Tablets |
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Prevents tumour development
Most Useful Review
I undergo courses and observe excellent results. Scientists recently discovered that low selenium levels in blood can trigger benign and malignant tumour development. Foods rich in selenium and vitamin E can prevent prostate cancer, while a combination of vitamin A, zinc, vitamin E, and selenium actively combats stomach cancer. They protect us from free radicals' damaging effects and are crucial for producing primary antioxidants.
Important for metabolism
Most Useful Review
Super Selenium not only contributes to youthful preservation but is also crucial for proper lipid, carbohydrate, and protein metabolism. Its benefits include improving thyroid gland function, strengthening the immune system, and reducing the risk of tumour diseases. It helps in normalising reproductive function, detoxifying the body, regulating hormonal levels, enhancing digestion, diminishing cardiovascular pathology risks, and improving skin and nail health, while boosting the efficacy of tocopherol and iodine.
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 Life Extension, Super Selenium Complex & Vitamin E, 200 mcg, 100 Vegetarian Capsules |
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Immunity booster noted
Most Useful Review
3 people found this helpful
It’s excellent! It effectively regulates immunity and increases anti-cancer properties. My family and I have been taking selenium for nearly six years since my father was diagnosed with lung adenocarcinoma. I discovered selenium's anti-tumour effects and chose this supplement for its benefits. We all feel that it enhances our antioxidant capacity and immunity. It’s become a staple in our household!
Immunity improved
Most Useful Review
Excellent! Selenium plays a critical role in metabolism, thyroid function, and bolstering the immune system while enhancing brain function and decreasing cardiovascular disease risk. With enough selenium, the body can effectively eliminate heavy metals. My experience corresponds with this—I've been taking it for a year and have noticed a significant improvement in my immunity. I highly recommend it!
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 NOW Foods, Selenium, 100 mcg, 100 Tablets |
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Immune system booster
Most Useful Review
96 people found this helpful
Excellent! Selenium plays a vital role in bolstering the immune system and enhancing brain function. I highly recommend it.
Brain function support
Most Useful Review
242 people found this helpful
Selenium is key for enhancing the immune system and brain function. I bought it for immunity and have since learned to combine it with iodine for better absorption, preventing potential harm from radicals.
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 Gaia Herbs, Rhodiola Rosea, 120 mg, 60 Vegan Liquid Phyto-Caps |
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Increases focus
Most Useful Review
4 people found this helpful
Like a bottle of energy, this product is effective. Since I started taking it, I've noticed a calming effect when I should be anxious. My energy levels have risen, and brain fog has diminished. I find myself much more focused and capable of tackling previously daunting tasks. My adrenals are grateful to iHerb for this game-changing product.
Improves brain function
Most Useful Review
Great, I adore all the products from this brand. Their quality is superb. Rhodiola aids in reducing stress, alleviates fatigue, mitigates symptoms of depression, and enhances brain function.
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 Doctor's Best, L-Theanine, 150 mg, 90 Veggie Caps |
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Mental clarity boost
Most Useful Review
The Japanese have discovered a unique agent that stimulates mental performance - L-theanine from green tea. It activates brain function without causing nervous excitability, promoting calmness and clarity of mind while reducing stress-induced pressure. This has been a revelation for me! After a month of use, my mood and endurance have significantly improved. I take it twice daily, and it causes no discomfort.
Night shift support
Most Useful Review
6 people found this helpful
This wonderful drug works like magic! I live on a night schedule and often find it hard to calm my brain after a heavy night shift. But these capsules have truly been my escape. Initially sceptical, I've realised how wrong I was to hesitate. Definitely recommended!
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 NOW Foods, L-Theanine, 100 mg, 90 Veg Capsules |
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Energy and clarity
Most Useful Review
5 people found this helpful
L-theanine is an amino acid that enhances mental alertness and creativity without overstimulating the nervous system. It helps maintain calm and mental clarity. Research indicates that a dosage of at least 500 mg is optimal for effectiveness. I wholeheartedly recommend this product for those seeking an enhancement in mental performance.
Calmness for dementia
Most Useful Review
2 people found this helpful
Very well! My 101-year-old mother, who has experienced a brain haemorrhage and suffers from dementia, often feels restless and sad. L-Theanine helps her feel calmer and more content. We are extremely pleased with its effects.
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 Jarrow Formulas, L-Carnitine, 500 mg, 100 Veggie Capsules |
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Daily energy boost
Most Useful Review
Great quality! I take it daily as a brain and energy booster in the morning. I have no complaints so far.
Brain support boost
Most Useful Review
1 people found this helpful
I've been using it since 2014. Carnitine is very helpful for both the brain and exercise, so I continue to take it. It truly is a high-quality product.
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 NOW Foods, L-Carnitine, 500 mg, 60 Veg Capsules |
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Memory improvement
Most Useful Review
1 people found this helpful
After several months of use, I have noticed significant improvements in my brain speed and memory.
Enhanced energy production
Most Useful Review
Honest review! L-carnitine carries out several crucial functions in the body: it boosts mental and physical energy, enhances stress resistance, detoxifies the body, reduces blood triglycerides, stimulates tissue regeneration, and has an antioxidant effect. This powerful substance energises the male body, enhancing reproductive functions and significantly improving sperm quality. Being a strong antioxidant, it shields sperm from oxidative stress. L-carnitine also transports fatty acids from fat stores to muscle cells, converting them into energy as ATP. In essence, the body utilises carnitine to turn fat into energy, which is vital, as fatty acids cannot penetrate cellular mitochondria without carnitine’s aid.
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 NOW Foods, L-Carnitine, 1,000 mg, 50 Tablets |
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Enhanced training performance
Most Useful Review
4 people found this helpful
Endurance and lightness are guaranteed! My trainer recommended L-carnitine. I work out six times a week, with varied intensity. I take it daily in the morning before training, which boosts my energy, enhances exercise effectiveness, and helps my brain stay clear post-training—essential for good performance. This supplement has improved my endurance during workouts, making my day easier.
Supports energy production
Most Useful Review
Good L-carnitine is vital in energy production by facilitating fatty acid transport into the cells for oxidation. It is crucial for heart and brain health and enhances muscle activity. L-carnitine helps prevent muscle fatigue and reduces stress. Consulting a doctor is advisable before use, especially if other medications are being taken.
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 Doctor's Best, High Potency Bromelain, 500 mg, 90 Veggie Caps |
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Inhibits glioma cell growth
Most Useful Review
I have been taking Bromelain for over 20 years as it is reported to inhibit the growth of glioma cells, a type of malignant brain tumour, in vitro. It acts as a proteolytic enzyme and COX-2 inhibitor.
Reduces inflammation
Most Useful Review
Excellent! This product is marvellous; I’ve used it as a proteolytic enzyme, taking it between meals three times a day, and it has significantly helped reduce inflammation associated with a tumour. Highly recommend!
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 Doctor's Best, NAC Detox Regulators with Seleno Excell®, 60 Veggie Caps |
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Reverses brain damage
Most Useful Review
96 people found this helpful
This supplement has been a lifesaver for me. After years of substance abuse, I felt lost until I discovered NAC's potential to repair brain damage. Within a week or two, I felt about 70% better, which was astonishing for such a simple remedy. I continue to take it daily for its anxiolytic effects and as a preventive measure against alcohol-related brain damage. I truly believe it saved my life.
Brain fog eliminated
Most Useful Review
31 people found this helpful
After successfully taking NAC a few years ago, I tried it again and it was worth it. The Dr's Best NAC Detox Regulators helped restore my glutathione levels, cleansing my liver and brain rapidly. By the second day, the brain fog was gone, and I slept deeply for eight uninterrupted hours. The quality is excellent; these capsules are essential for detoxifying the body from toxins.
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 Nature's Way, Organic MCT Oil, 16 fl oz (480 ml) |
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Promotes longevity
Most Useful Review
9 people found this helpful
Excellent! MCT oil is vital for youth, providing energy by going straight to the liver without requiring carnitine or bile acids. It allows for energy from glucose or ketones, promoting brighter brain function and preserving organ health while preventing insulin resistance and cognitive decline.
Essential daily supplement
Most Useful Review
5 people found this helpful
A game changer! This MCT oil from Nature’s Way is now an essential part of my daily routine. Sourced from premium coconuts, it boasts 100% potency with no filler oils. I've experienced significant skin improvement since its use, and it energises my brain and body while keeping me feeling full. It's flavourless and odourless, perfect for meals, and I love that it remains liquid even when refrigerated. Just remember not to overuse, and consult a healthcare professional if necessary.
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 NOW Foods, Turmeric & Bromelain, 90 Veg Capsules |
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Brain health effect
Most Useful Review
This product is fantastic for when I'm feeling unwell or suffering from joint pain. Moreover, it has a remarkable impact on brain health, making it indispensable in my daily routine.
Strengthens immune system
Most Useful Review
This product significantly contributes to overall health by suppressing inflammatory factors in the body, thereby enhancing the immune system's resilience. Furthermore, Curcumin and bromelain are beneficial for mental performance, supporting healthy brain function with their neuroprotective properties. Additionally, it promotes the well-being of the digestive system, joints, and pancreas.
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 Doctor's Best, Benfotiamine 150 + Alpha-Lipoic Acid 300, 60 Veggie Caps |
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Enhanced brain function
Most Useful Review
1 people found this helpful
Perfectly! This product is ideal! My brain functions like clockwork, with heightened attention and concentration. I feel more invigorated, and my health has improved significantly, alongside numerous pleasant bonuses. It's truly a fantastic find for someone in today's world!
Maintained brain activity
Most Useful Review
1 people found this helpful
I constantly order this for my mum, who is over 60. These supplements are excellent, helping to maintain her brain activity! She is delighted and has experienced no side effects.
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 Life Extension, N-Acetyl-L-Cysteine, 600 mg, 60 Capsules |
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Improves memory significantly
Most Useful Review
121 people found this helpful
Improves brain function. I took it for recovery after surgery. During long subway trips, my head began to spin, feeling as if I had "rested" it. I consumed the drug for a month, taking 2 capsules daily, morning and evening, and the symptoms ceased. Overall, my memory and performance have significantly improved.
Enhanced brain activity
Most Useful Review
76 people found this helpful
I read an article about this product, which yields results in improving brain activity. While my general condition has improved, I have become more productive. The size of the capsules is ideal.
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 NOW Foods, Turmeric Curcumin Gels, 475 mg, 120 Softgels |
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Memory improvement
Most Useful Review
To prevent brain ageing, I discovered this product containing only curcumin, which I began taking. Other supplements with turmeric extract are available, but curcumin alone is less effective. After around a week, I noticed a recovery in my memory, and my forgetfulness significantly decreased. I am no longer vague throughout the day, and my work efficiency has clearly improved. I appreciate the high quality. I take it daily; as it has no taste, I find it easy to consume after meals. Compared to other products, this soft gel capsule is much easier to swallow, and it doesn’t cause me any discomfort. I intend to continue using it for as long as possible.
Liver and brain support
Most Useful Review
This is an excellent anti-inflammatory supplement. I generally need to take 4 to 8 tablets to feel an improvement. It is fantastic for my liver and brain health.
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 Mason Natural, Vitamin B-1, 250 mg, 100 Tablets |
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Effective brain boost
Most Useful Review
18 people found this helpful
Tide for brains is remarkable! Administered sublingually, it clears the head remarkably (though the taste is not ideal). You can take it with water and feel its effects instantaneously. It alleviates fatigue as if by magic. Just a quarter tablet is more than sufficient, especially given the draconian dose of 16,000%. The tablet breaks easily; the effects last long, and quality is superb. The container is dark plastic and reasonably priced - five stars overall. I highly recommend this!
Sharpens clarity
Most Useful Review
1 people found this helpful
I love these for combating 'brain fog.' At 61, I sometimes feel a bit addled and struggle with word recall. These were recommended, and they've made a tremendous difference for my mental clarity.
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 Solgar, Vitamin B1, 500 mg, 100 Tablets |
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Energy and focus enhanced
Most Useful Review
Thiamine (Vitamin B1) has become an essential supplement for maintaining energy and improving my nervous system function. Since I began taking it, I've felt more energetic and better able to handle mental stress. Thiamine aids in converting food into energy and supports brain and nervous system function—crucial during stressful times or increased cognitive demands. The capsules absorb easily and are side-effect free. It's an excellent choice for those looking to enhance cognitive function, boost energy levels, and improve overall well-being!
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 Jarrow Formulas, Ubiquinol, QH-Absorb, Max Absorption, 100 mg, 120 Softgels |
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Increases brain health
Most Useful Review
2 people found this helpful
Excellent! Ubiquinol is the most absorbable form of CoQ10. It's pricier, but worth the investment! It significantly boosts blood levels of this essential substance, crucial for maintaining good brain and heart health as we age. I take 400 mg daily for improved results in sports and activities that require mental energy. This bottle of 120 softgels is excellent!
Fights fatigue
Most Useful Review
This high-quality Ubiquinol type Q10 is better absorbed than other forms. The size may be a bit large, but it’s suitable for individuals with heart conditions or older age. It energises me, and I don’t feel fatigued easily. It not only provides energy but also combats free radicals.
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 Qunol, Mega CoQ10 Ubiquinol, 100 mg, 60 Softgels |
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Boosts vitality
Most Useful Review
I purchased this supplement for my mother-in-law, who takes statins that deplete coenzyme Q10. This product, containing ubiquinol for better assimilation, provides a noticeable increase in energy and positively impacts brain function.
Increases energy
Most Useful Review
Absolutely essential for those over 40. This reduced form of ubiquinone offers better absorption. It provides energy and strength for the heart's and brain's proper functioning. There's a good balance of price and quality!
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 NOW Foods, Double Strength Taurine, 1,000 mg, 250 Veg Capsules |
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Significant improvement
Most Useful Review
117 people found this helpful
I had a haemorrhagic stroke six years ago, and my brain is damaged. After consuming energy drinks for university assignments, my brain fog lifted, and I could manage my anger better. Since then, I began taking a B vitamin supplement, achieving a night-and-day difference in my daily life.
Seizure control
Most Useful Review
7 people found this helpful
I have been using taurine for years to manage my simple partial epileptic seizures, previously treated with Tegretol, which clouded my mind. After 15 years without breakouts and having regained my mental clarity, I confidently choose Now's Double Strength for consistent results.
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 Solgar, Taurine, 500 mg, 250 Vegetable Capsules |
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Improved cognitive clarity
Most Useful Review
11 people found this helpful
Buy a second time! I liked the action. After about a month, I noticed my brain feels sharper, and my episodes of rapid heart rate have stopped worrying me. Generally, on some days, I noted that I feel good :) I purchased it last spring and have now decided to buy again.
Nervous system support
Most Useful Review
I purchased this taurine on my trusted nutritionist's advice, who believes it is the best on the dietary supplement market. I began taking it alongside lecithin to improve bile rheology, and I am pleased with the results. Taurine also possesses antioxidant properties which enhance brain function, metabolism, and nurture the nervous system.
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 Jarrow Formulas, Taurine , 1,000 mg, 100 Capsules |
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Nerve protection
Most Useful Review
Taurine is a miraculous sulfur-containing amino acid known for stimulating nerve cell growth, protecting brain cells, and improving overall health, including eyesight and liver function. Its myriad benefits have made me quite fond of this supplement, which I intend to take for three months.
Stimulates healing
Most Useful Review
6 people found this helpful
Excellent! A doctor prescribed taurine for my dyskinesia and bile flow issues, but its benefits extend beyond that. Taurine acts as a neurotransmitter in the brain, possesses anticonvulsant properties, and supports energy and healing processes in the body. I take one capsule daily before breakfast; they are reasonable in size and taste, and the quality is assured. Always consult your doctor before use!
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 NOW Foods, Taurine Pure Powder, 8 oz (227 g) |
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Improved memory function
Most Useful Review
6 people found this helpful
I have been treating a brain tumor for two years (it was stage 4). I drink taurine regularly; it is essential for normal liver function and detoxification. It also improves metabolism and stimulates new cell growth in the hippocampus, enhancing memory. In post-COVID times, memory loss is prevalent, making this relevant. In those two years, combining taurine with SAM-e, milk thistle and herbs helped regress fibrosis from stage 4 to 1. My depression has lifted, and I've overcome anxiety! I sleep well and no longer experience panic attacks. Taurine protects the liver and aids brain health — it truly is beneficial. If you found my review helpful, please give it a thumbs up.
Calming effects
Most Useful Review
Taurine is one of the best options for cardiovascular and brain health. It counteracts excessive neuroexcitory effects of glutamate, calming you down, making it perfect before interviews. I take one to two grams daily to elevate GABA levels for its antianxiolytic effect.
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 NOW Foods, Garlic Oil, 1,500 mg, 250 Softgels |
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Boosts metabolism
Most Useful Review
Garlic oil serves as a broad-spectrum antibacterial agent, enhancing the body's immune functions and metabolism. Its antibacterial and anti-inflammatory properties protect the liver and regulate blood sugar levels. Compounds in garlic inhibit the growth of cancer cells, providing significant anti-cancer effects. The product offers excellent value for money.
Lowers cholesterol levels
Most Useful Review
Following the stenting of coronary vessels and a brain aneurysm, I confidently endorse this garlic extract for maintaining cardiovascular health. While statins showed no effect, this supplement normalised my cholesterol levels within six months, and it is also used by my family and friends. If you found this helpful, please click "Yes."
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 NOW Foods, Beta-Glucans, with ImmunEnhancer, Extra Strength, 250 mg, 60 Veg Capsules |
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Reduced tumours observed
Most Useful Review
2 people found this helpful
Excellent! My mother orders these pills for their formulation; the mushrooms and beta-glucans positively impact the reduction of neoplasms or tumours within the body.
Immune modulation highlighted
Most Useful Review
β-glucan is vital for the immune system, enhancing immune cell activity and promoting their proliferation and differentiation. It assists in identifying and eliminating pathogens, besides offering anti-inflammatory, anti-tumour, and antioxidant properties that regulate immune function. Furthermore, it has antibacterial, antiviral, and lipid-lowering effects that benefit overall health.
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 NOW Foods, Boron, 3 mg, 250 Veg Capsules |
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Mental clarity boost
Most Useful Review
7 people found this helpful
As one of the top supplements for men, I tried it for its positive effects on testosterone. However, I found it also improved my joint function and strength during muscle contractions. I had been suffering from persistent brain fog, but boron significantly alleviated it. After using this supplement for just ten days at 9mg, I experienced noticeable improvements in my mental clarity from the first use. The quality of this product is excellent, and its benefits are vast.
Beneficial for brain
Most Useful Review
Boron Now is a fantastic supplement, and it is exceptionally beneficial for the brain.
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 NOW Foods, Apple Pectin, 700 mg, 120 Veg Capsules |
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Brain fog treatment
Most Useful Review
5 people found this helpful
Apple pectin has been notable in dissipating brain fog. The BDNF it helps produce is crucial for repairing brain nerve cells, especially when dealing with issues like brain degeneration and strokes. It aids in prebiotics transforming into butyrate, which is exceptionally beneficial when addressing cognitive impairments and enhancing rehabilitation.
Memory support
Most Useful Review
1 people found this helpful
This product effectively supports brain function and memory improvements while also ensuring proper intestinal health.
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 BulletProof, MCT Oil, 16 fl oz (473 ml) |
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Quick energy boost
Most Useful Review
Enjoy a clean energy source! Bulletproof Brain Octane C8 MCT Oil offers a rapid and clean energy supply for the brain and body. It’s derived from pure coconut oil and is rich in C8 (caprylic acid). This MCT oil supports mental clarity and cognitive function, making it ideal for those needing sustained mental energy while on a low-carb diet.
Improved energy levels
Most Useful Review
3 people found this helpful
I was excited after reading the reviews, and as soon as I received it, I mixed it with coffee. It's tasteless, the size is perfect, and the ingredients are top-notch. I felt the effects immediately. My brain fog symptoms have improved, I feel more energetic, and numbness in my body has also significantly enhanced.
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 NOW Foods, Alpha GPC, 300 mg, 60 Veg Capsules |
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Improved thinking speed
Most Useful Review
21 people found this helpful
This is a powerful brain stimulant! After taking it, I felt a significant increase in cognitive function, remembering material was easier, and I experienced a 30% boost in thinking speed. It also gave me a sense of being superhuman. Just remember to adhere to the dosage and use only one capsule. I wholeheartedly recommend it!
Faster stroke recovery
Most Useful Review
12 people found this helpful
Alpha-GPC is essential for brain health, providing choline for cell membranes and myelin production. It releases acetylcholine, supporting cognitive function. After my mother's stroke, which was detected rapidly, I purchased it for her. She recovered faster thanks to this supplement, which she took consistently for six months.
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 NOW Foods, Acetyl-L-Carnitine, 500 mg, 200 Veg Capsules |
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Effective recovery aid
Most Useful Review
94 people found this helpful
It improves brain function. I used it for recovery during long subway rides when I would feel dizzy, resembling a state of recharge. After taking one capsule daily for a month, those symptoms ceased, and my memory and performance improved significantly. Please rate my answer if it was helpful!
Enhanced memory function
Most Useful Review
12 people found this helpful
The quality is excellent. The jar is good, with no taste and average-sized capsules. It significantly improves brain function. I took it for recovery during lengthy subway trips, alleviating dizziness. After a month of daily capsules, my symptoms diminished and my memory and performance greatly improved.
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 NOW Foods, Astaxanthin, 4 mg, 90 Softgels |
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Brain anti-aging effects
Most Useful Review
1 people found this helpful
Astaxanthin is a unique red pigment found in shrimp and crabs. Its ability to penetrate the brain barrier makes it effective in anti-aging for the brain, significantly benefiting both brain and eye health.
Supports eye health
Most Useful Review
Astaxanthin crosses the brain and retina barrier, providing effective antioxidant protection to the eyes, brain, and nervous system while supporting retinal and overall eye health. It fosters a healthy inflammatory response.
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 NOW Foods, Sports, L-Glutamine, Double Strength, 1,000 mg, 120 Veg Capsules |
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Helpful for brain
Most Useful Review
I initially bought it because I heard it was beneficial during exercise, but I believe it supports brain function more than physical activity. The ingredients and effects are impressive.
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 NOW Foods, Lutein, 10 mg, 120 Softgels |
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 Jarrow Formulas, PQQ, 20 mg, 30 Capsules |
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Supports cellular energy
Most Useful Review
14 people found this helpful
It's beneficial to continue with this product, which I prescribe to patients. It supports energy production and the creation of new mitochondria, aiding brain function and memory. To see optimal results, patients should take it for three months, as it significantly supports immune cells and promotes self-healing.
Cognitive enhancement
Most Useful Review
1 people found this helpful
I've recently tried PQQ, and the quality is outstanding, with top-grade ingredients ensuring efficacy. Since incorporating it, I've noticed reduced stress and improved cognitive function. The clarity and focus for my brain are significant. My sleep quality and cholesterol levels have also improved, likely due to PQQ's support of mitochondrial function. Additionally, energy levels have noticeably increased. The taste is neutral, making it easy to take daily. Overall, PQQ delivers numerous health benefits, particularly for brain health and energy.
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 Doctor's Best, MSM with OptiMSM®, 3,000 mg, 360 Capsules (1,000 mg per Capsule) |
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Joint health improvement
Most Useful Review
1 people found this helpful
It's beneficial without side effects, offering numerous advantages of sulfur, notably for joint health and enhancing the skin, hair, and breathing. Additionally, it aids in removing aluminium from the brain, potentially reducing Alzheimer's risk in the future. I will certainly repurchase this product.
Supports recovery
Most Useful Review
Methylsulfonylmethane (MSM) with OptiMSM from Doctor's Best contains easily absorbed natural sulphur compounds. Known as a 'beauty mineral', it plays a vital role in collagen production and joint mobility. Its analgesic and anti-inflammatory properties assist with arthritis, and it may enhance post-traumatic recovery while fostering immune responses. MSM can also boost brain activity and overall body condition.
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 NOW Foods, Certified Organic Spirulina, Double Strength, 1,000 mg, 120 Tablets |
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Rich in nutrients
Most Useful Review
1 people found this helpful
Spirulina is an impressive alga I consume daily, taking three tablets with each meal. Its remarkable nutrient profile includes protein, vitamins, and essential minerals, all of which contribute to developing healthy nervous tissue. It’s also a superior source of beta-carotene, providing protective benefits for the brain and eyes.
Clearer head
Most Useful Review
1 people found this helpful
I felt the effect on my body by the third to fourth day. I began taking it during a stage of severe physical exhaustion and an upset stomach. The first thing I noticed was that my mind felt clearer, as if the fog had dissipated and the cobwebs had been cleared from my head. I am extremely grateful for this alone, as I hadn’t been able to gather my thoughts for a month. Additionally, my body has also improved, alongside a proper diet and sleep.
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 NOW Foods, L-Ornithine, 500 mg, 120 Veg Capsules |
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Sharpens focus
Most Useful Review
10 people found this helpful
I struggled with concentration due to what I believed was excess ammonia after protein intake. After just two days of taking ornithine, my brain felt clearer, and I was able to think more clearly. I take it throughout the day, finding it effective as one of the essential amino acids.
Increases alertness
Most Useful Review
I take this supplement to maintain liver health. It notably decreases brain fog while enhancing my concentration and energy levels. I find the standard-sized capsules easy to swallow, and there have been no unpleasant side effects.
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 NOW Foods, 5-HTP, 50 mg, 180 Veg Capsules |
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Improved sleep quality
Most Useful Review
6 people found this helpful
I use this product consistently. It has enhanced my sleep, increased brain activity, and alleviated anxiety and stress. I always feel wonderful and in a positive mood without experiencing nervous breakdowns or panic attacks. I will continue to use it! It also noticeably reduces my appetite and other undesirable habits. The taste is acceptable. My serotonin levels normalised during testing. The benefits are evident.
Eased emotional strain
Most Useful Review
2 people found this helpful
I have been searching for a dietary supplement that helps control my emotional state. With recent sunny days and ongoing work and family issues, I found myself feeling overwhelmed. Almost immediately after taking it, life felt easier, and my outlook improved. I noticed my brain functioning better, and waking up became simpler, rather than difficult. Overall, my life appears to be improving, and this affordable supplement is truly working for me.
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 NOW Foods, L-Carnosine, 500 mg, 100 Veg Capsules |
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Mood and memory improved
Most Useful Review
47 people found this helpful
I was introduced to carnosine by my dietician while managing a diet that affected my memory. Within weeks of taking it, my mood improved significantly, and I no longer experienced fatigue or sluggishness. This product remarkably enhanced my cognitive functions and I highly recommend it for maintaining brain health.
Overall health support
Most Useful Review
5 people found this helpful
I absolutely love NOW Foods L-Carnosine! This product is great for maintaining health and well-being. It significantly improved my memory, concentration, and energy levels after regular use. The capsules are convenient, making them a reliable choice for overall health maintenance. I highly recommend it!
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 Doctor's Best, Extra Strength Ginkgo, 120 mg, 360 Veggie Caps |
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Improved circulation
Most Useful Review
929 people found this helpful
Excellent! A really useful supplement; it enhances blood circulation in the brain, and I can see the results. Fantastic!
Headache reduction
Most Useful Review
221 people found this helpful
To maintain memory and a healthy brain, my family regularly takes ginkgo biloba. Sometimes, I double the dosage as 1 capsule seems small. This supplement is well tolerated, reducing my frequent headaches significantly, and I will continue taking it as I feel much better overall.
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 Citrucel, Methylcellulose Fiber Therapy for Irregularity, 180 Fiber Caplets |
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Improved circulation
Most Useful Review
929 people found this helpful
Excellent! A really useful supplement; it enhances blood circulation in the brain, and I can see the results. Fantastic!
Headache reduction
Most Useful Review
221 people found this helpful
To maintain memory and a healthy brain, my family regularly takes ginkgo biloba. Sometimes, I double the dosage as 1 capsule seems small. This supplement is well tolerated, reducing my frequent headaches significantly, and I will continue taking it as I feel much better overall.
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 Jarrow Formulas, PS100, Phosphatidylserine, 100 mg, 120 Softgels |
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Highly recommended
Most Useful Review
42 people found this helpful
Jarrow PS-100 was recommended to me years ago by a friend with a PhD in biochemistry who owns a vitamin store. It works wonders for brain function.
Clearer thoughts
Most Useful Review
20 people found this helpful
I often made mistakes at work, struggled with interpersonal relationships, and had a dull mind, but after using various supplements without clear effects, I tried phosphatidylserine. I took one tablet in the morning and noon, and soon my head felt clearer with organized thoughts. I can now handle social troubles better, and I believe the mental stress damage has lessened. My concentration has increased significantly at work and school, prompting me to order double the amount.
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