Medical Researches
Possibly Effective
Based on 83 Researches
Lactobacillus improves IBS-C symptomsClinical assessment and cytokines level in constipation-predominant irritable bowel syndrome participants treated with Lactobacillus-containing cultured milk drink.
Consistent findings support treatment benefit
We investigated how a cultured milk drink containing Lactobacillus acidophilus affects symptoms of constipation in individuals with irritable bowel syndrome (IBS-C). Over 30 days, participants consumed the drink daily.
At the end of the study, an impressive 97.4% of IBS-C participants reported improvement in their constipation-related symptoms. We also noticed reductions in intestinal transit time and pro-inflammatory cytokines linked to IBS. Overall, this suggests that including this cultured milk drink may be a beneficial addition to IBS-C treatment plans.
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Probiotics improve constipation symptomsImpact of a probiotic chewable tablet on stool habits and microbial profile in children with functional constipation: A randomized controlled clinical trial.
High relevance to childhood constipation.
We conducted a randomized, placebo-controlled trial involving 92 children aged 4 to 12 with functional constipation. Over four weeks, we provided one group with a probiotic chewable tablet containing specific strains and compared their experiences to a placebo group.
The findings were promising; the probiotic group reported a significant improvement in stool frequency and a decrease in hard defecation. Specifically, hard stools decreased from 43% to 14%, while normal defecation increased from 56% to 80%. This study highlights the potential of probiotics as a valuable option for managing constipation in children.
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We evaluated how lactobacillus acidophilus, both alone and in a mix with other bacteria, might relieve constipation caused by loperamide in rats. Over 14 days, we noticed that the groups receiving probiotics had significantly heavier and wetter stools compared to control animals.
Notably, the CKDBP group, a blend of multiple bacteria, showed the greatest improvement in intestinal transit. Measures like mucosal length and mucus secretion were also significantly enhanced in all probiotic-treated groups, highlighting their potential to alleviate constipation symptoms effectively.
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We investigated the effects of Lactobacillus rhamnosus (LRJ-1) on constipation in mice. The study revealed that oral treatment with LRJ-1 led to significant improvements in constipation by increasing levels of a gut compound called γ-aminobutyric acid (GABA).
We also found that the beneficial impact of LRJ-1 was linked to the growth of specific intestinal bacteria and the activation of certain nerve pathways in the gut. While these findings are promising, they confirm the potential of LRJ-1 in addressing constipation through its influence on gut health.
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Probiotic improves IBS-C symptomsEffect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial.
High relevance for constipation treatment
We examined the effects of Lacticaseibacillus rhamnosus IDCC 3201 on patients suffering from irritable bowel syndrome with constipation (IBS-C). In a robust study involving 30 participants, we used a randomized, double-blind, placebo-controlled design.
After eight weeks of treatment, the probiotic group reported significant improvements in bowel activities and discomfort linked to constipation. Notably, symptoms like abdominal bloating also improved.
Our findings suggest that this probiotic might help enhance gut health by promoting beneficial microbes and their metabolites.
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User Reviews
My son had a poor appetite and frequent constipation. Local doctors couldn’t help, so I decided to give him probiotics. Unlike the large Russian capsules, he eats these easily and with pleasure. Miraculously, after two weeks, his appetite returned, and he now goes to the toilet without distress. We’ll definitely order more!
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This product has been excellent for us. It relieved my child's year-long constipation within a week of taking it. Now they go regularly, and we'll repeat the course in autumn.
This probiotic has been a lifesaver after years of my child suffering from constipation. They had dense stools, abdominal pain, and poor appetite. After the course, their appetite improved, and they now go to the toilet daily with soft stools. Plus, they enjoy the berry taste.
My daughter has been taking this probiotic since she was 2.5 years old. Since then, her eczema flare-ups have reduced significantly and she has had no constipation issues.
We’ve been battling constipation in my child since she was six months old. Now at three, she loves the taste of this probiotic and has had no problems with her stools for several months! I plan to repeat the course in three months.