Tumeric
10
Achieved remission
Most Useful Review
I have been taking 2 gms (4 capsules) of curcumin daily since my stage 4 breast cancer diagnosis a year ago. Remarkably, I went into remission within three months, and there has been no evidence of cancer for the past eight months.
9.5
Cancer remission
Most Useful Review
After taking curcumin for about four months, I noticed a significant boost in my immune system. I also recommended it to my aunt, who had stage 4 lymphoma, and I am thrilled to share that her cancer has gone into remission after about a month on it.
Multivitamins
9.5
Immune system support
Most Useful Review
I took Mega-Zim instead of the German Wobenzym, and it has proven to be even better in terms of enzyme composition. I took 5 tablets four times a day for ten days. It played a crucial role in exposing cancer cells to my immune system, allowing it to fight effectively. I consumed Mega-Zim an hour before meals with warm water, specifically to enrich my blood with enzymes. The quality and results were excellent, and I highly recommend it.
9.5
No digestive issues
Most Useful Review
I often experience diarrhoea from enzymes, but these caused no problems at all. I felt much better after taking them, and they were recommended by my cancer options doctor.
Enzymes
8
Coenzyme Q10 shows limited benefits
Exploring potential additive effects of 5-fluorouracil, thymoquinone, and coenzyme Q10 triple therapy on colon cancer cells in relation to glycolysis and redox status modulation.
Most Relevant Research
Our research aimed to understand the effects of coenzyme Q10 (CQ10) in combination with other treatments, specifically 5-Fluorouracil (5-FU) and thymoquinone (TQ), on human colorectal cancer cells. We conducted experiments using three types of colon cancer cell lines: HT29, SW480, and SW620.
Through a range of tests, we observed that when used alone, CQ10 didn't showcase remarkable anticancer effects compared to TQ. However, when CQ10 was part of a triple therapy with 5-FU and TQ, the combination significantly enhanced the anticancer impact. The triple therapy was particularly effective in promoting cell death in cancer cells and inhibiting pathways that help tumors grow.
Notably, our findings suggest that the combination treatment could alter cellular metabolism towards a less favorable environment for cancer, emphasizing the potential of TQ over CQ10 alone. Our study demonstrated that while CQ10 contributes positively in combination, it does not stand out independently in enhancing the efficacy against colon cancer.
Through a range of tests, we observed that when used alone, CQ10 didn't showcase remarkable anticancer effects compared to TQ. However, when CQ10 was part of a triple therapy with 5-FU and TQ, the combination significantly enhanced the anticancer impact. The triple therapy was particularly effective in promoting cell death in cancer cells and inhibiting pathways that help tumors grow.
Notably, our findings suggest that the combination treatment could alter cellular metabolism towards a less favorable environment for cancer, emphasizing the potential of TQ over CQ10 alone. Our study demonstrated that while CQ10 contributes positively in combination, it does not stand out independently in enhancing the efficacy against colon cancer.
9.5
Effective cancer treatment
Most Useful Review
My favourite dietary supplement! Serrapeptase is one of the safest and most effective anti-inflammatory drugs, gently breaking down fibrous formations. It has helped with conditions related to cancer, promotes normal blood flow, and cleanses toxins. I have taken it regularly, and it feels like a nanoscalpel with no side effects. I appreciate its benefits and will keep buying it.
Inositol
9
Myo-inositol affects prostate cancer cells
Proteomic Analysis of Anticancer Effect of Myo-inositol in Human Prostate Cancer (DU-145) Cell Line.
Most Relevant Research
We investigated the potential benefits of Myo-inositol, a naturally occurring sugar alcohol, on DU-145 prostate cancer cells. By treating these cancer cells with various doses of Myo-inositol, we determined its half-maximal inhibitory concentration (IC50) using a simple method that measures cell viability.
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
9.5
Menstrual cycle restoration
Most Useful Review
Unbelievably, inositol has been instrumental in treating polycystic ovaries, aiding hormonal balance, stabilising the cardiovascular system, and prompting ovulation. It helps to lower triglycerides and reduces the risk of cancer.
Vitamin C
9
Vitamin C enhances immune response
Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response.
Most Relevant Research
We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1.
By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.
Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.
Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
9.5
Stops cancer development
Most Useful Review
My moles stopped itching after I began taking green tea extract for cardiovascular health. After a stroke, I noticed changes and started the extract. In weeks, the itching subsided; I later learned it’s a strong antioxidant preventing cancer and slowing ageing.
Polygonum Cuspidatum Complex
9.5
Inflammation relief
Most Useful Review
Resveratrol is an excellent, tested product that aids in preventing cancer and relieving inflammation. After suffering from increased leukocyte levels for years, I took Resveratrol for four months, and subsequent tests showed normal results. Now, I take it twice a year for prevention.
9.5
Cancer therapy
Most Useful Review
Resveratrol is a well-studied natural compound with antioxidant properties. It is known to be anti-cancer and serves as a therapeutic agent.
Inositol Hexaphosphate
9.5
Significant cancer support
Most Useful Review
IP6 is an incredible supplement, significantly reducing the formation of harmful AGEs that damage our organs and contribute to diabetes complications. Its ability to lower these substances by a remarkable 40% is impressive. I recommend taking it before meals for optimal effects. IP6 is also a powerful anti-cancer agent. For those with diabetes and insulin resistance, I've found it synergistic with other supplements and providing substantial overall protection and energy boost.
9.5
Top anti-cancer choice
Most Useful Review
IP6 is my top anti-cancer supplement. It’s crucial to take it with distilled water, well away from food or other supplements. I find it most effective when taken first thing in the morning.
Spirulina
9.5
Cancer treatment benefits
Most Useful Review
Spirulina is a source of plant protein and B vitamins, particularly B12, making it beneficial for vegetarians. While it aids in weight loss, healthy eating and exercise are still essential. Spirulina boosts the immune system, helps with anemia by increasing hemoglobin, and has anti-cancer properties through phycocyanin, which can inhibit cancer cell growth. It is vital to use it in moderation and consider its effects on the body.
9.5
Antioxidant properties
Most Useful Review
Spirulina is rich in phytochemicals like phycocyanin, which are powerful antioxidants. They help reduce oxidative damage, protect against cancer, and lower heart disease risk.
Quercetin
9.5
Quercetin enhances cancer treatment efficacy
Active tumor targeting by core-shell PDMS-HA nanoparticles with sequential delivery of doxorubicin and quercetin to overcome P-glycoprotein efflux pump.
Most Relevant Research
We explored the impact of quercetin when used alongside doxorubicin in treating breast cancer. In our study, we delivered these two compounds using specialized polydimethylsiloxane nanoparticles, which were designed to enhance their effectiveness in targeting cancer cells.
Quercetin plays a crucial role by blocking the P-glycoprotein efflux pump. This action helps increase the intracellular levels of doxorubicin, leading to better cell death and more effective treatment outcomes. The combination of these two agents helps to tackle the problem of cancer cell resistance to drugs, making it easier for treatment to work.
Our research demonstrated that the sequential delivery of doxorubicin followed by quercetin significantly reduced tumor size in experimental models compared to using either treatment alone. We observed noticeable cell death and inhibited tumor growth in the tested breast cancer cells.
Overall, the findings suggest that quercetin can effectively support chemotherapy by reversing drug resistance and enhancing the anticancer effects of doxorubicin when they are delivered together. The approach not only shows promise in bolstering treatment efficacy but also indicates minimal toxicity to normal tissues.
Quercetin plays a crucial role by blocking the P-glycoprotein efflux pump. This action helps increase the intracellular levels of doxorubicin, leading to better cell death and more effective treatment outcomes. The combination of these two agents helps to tackle the problem of cancer cell resistance to drugs, making it easier for treatment to work.
Our research demonstrated that the sequential delivery of doxorubicin followed by quercetin significantly reduced tumor size in experimental models compared to using either treatment alone. We observed noticeable cell death and inhibited tumor growth in the tested breast cancer cells.
Overall, the findings suggest that quercetin can effectively support chemotherapy by reversing drug resistance and enhancing the anticancer effects of doxorubicin when they are delivered together. The approach not only shows promise in bolstering treatment efficacy but also indicates minimal toxicity to normal tissues.
8.8
Improved wellbeing
Most Useful Review
I have multiple sclerosis, but this supplement has been stunningly effective. At 52, my health has improved significantly. Quercetin, a powerful antioxidant, along with bromelain, is helping my treatment against cancer. I only relied on these supplements and avoided antibiotics throughout my recovery. I consistently take them for ongoing health and quality of life.
Selenium
9
Selenium improves colon cancer treatment
Efficacy Evaluation of Selenium-enriched Akkermansia muciniphila in the Treatment of Colon Tumor Mice.
Most Relevant Research
We aimed to understand the impact of selenium-enriched Akkermansia muciniphila (Se-AM) on colon cancer, specifically looking at its effectiveness in treating tumors in mice. By enriching the probiotics with inorganic selenium, we prepared Se-AM and evaluated its performance against colon cancer cells using a mouse model.
Our findings revealed that Se-AM was effective in killing colon cancer cells, notably the CT26 cells. The effectiveness seemed to depend on the concentration, indicating that higher doses were better at destroying these cancer cells. In addition to this direct killing effect, we saw that Se-AM played a therapeutic role in mice with established tumors by reducing tumor size and positively altering inflammatory markers in the colon.
Importantly, treatment with Se-AM restored gut microbiota diversity back to levels similar to healthy controls. We observed a notable increase in beneficial bacteria, which suggests that Se-AM not only addresses cancer cells but also promotes a healthier gut environment. Furthermore, we didn't find any adverse effects on vital organs in the mice, highlighting the safety of this treatment.
Overall, our work indicates that Se-enriched Akkermansia muciniphila has promising potential in the fight against colon cancer, providing both direct anti-cancer effects and supporting gut health.
Our findings revealed that Se-AM was effective in killing colon cancer cells, notably the CT26 cells. The effectiveness seemed to depend on the concentration, indicating that higher doses were better at destroying these cancer cells. In addition to this direct killing effect, we saw that Se-AM played a therapeutic role in mice with established tumors by reducing tumor size and positively altering inflammatory markers in the colon.
Importantly, treatment with Se-AM restored gut microbiota diversity back to levels similar to healthy controls. We observed a notable increase in beneficial bacteria, which suggests that Se-AM not only addresses cancer cells but also promotes a healthier gut environment. Furthermore, we didn't find any adverse effects on vital organs in the mice, highlighting the safety of this treatment.
Overall, our work indicates that Se-enriched Akkermansia muciniphila has promising potential in the fight against colon cancer, providing both direct anti-cancer effects and supporting gut health.
9.5
Boosts cancer defence
Most Useful Review
This mineral supplement is vital for immunity and thyroid health. Selenium acts as a powerful antioxidant, combating atherosclerosis, cancer, infertility risk, and chronic fatigue. I recommend it for improving brain function and reducing cardiovascular disease risks.
Oleuropein
8.8
Promising against cancer
Most Useful Review
A very useful drug! The oleuropein in olive oil contributes to its medicinal properties. Olive leaves have high oleuropein content, making the extract a valuable nutrient source. Research into olive leaf extracts shows promise in preventing diseases, including hypertension, heart disease, diabetes, and cancer.
8.8
Supports cancer defense
Most Useful Review
We use this for the whole family to boost immunity. Olive leaves possess various beneficial properties, improving cardiovascular health and fighting diabetes and cancer, while enhancing immune defences. The natural composition lends the company my trust.
9.5
Effective treatment
Most Useful Review
I have been battling basal cell cancer and tried everything, but oregano oil is the only treatment that worked for me. I applied it twice daily and took two drops under my tongue each time. It's remarkable. Thank you!
8.8
Immune support
Most Useful Review
I have cancer, and I discovered through a holistic doctor that wild oregano oil aids breast cancer patients. It keeps my immunity strong, especially when travelling. I managed to avoid illness, and it also helped my gums heal after dental work, without harming my gut flora. Its potent quality, particularly the Carvacrol concentration, is impressive.
Cranberry
8.8
Cranberry cancer prevention
Most Useful Review
Cranberry is wonderful for combating diseases linked to urinary tract infections and plays a significant role in preventing cardiovascular diseases, ageing, and cancer. Furthermore, it helps maintain the balance of intestinal flora and boosts immune defences against infection.
8.8
Cranberry benefits cancer
Most Useful Review
The benefits of cranberry are numerous: it enhances immunity, addresses urinary tract issues, and prevents gastric problems including cancer. However, those with gastroesophageal reflux should avoid it. Cranberry can also support heart health, lower blood pressure, and reduce cholesterol. It may interact with certain medications, so consulting a doctor before consuming is advisable.
Coconut Oil
9.5
Cancer risk reduction
Most Useful Review
Coconut oil is excellent for maintaining healthy fat levels, lowering the risks of atherosclerosis, cardiovascular disease, and even cancer. After consistent intake of 2-3 capsules daily, I noticed my hair shines, and my skin is well-nourished and moisturised.
8.8
Cancer treatment innovator
Most Useful Review
Beating cancer! I utilise these tablets and prepare food using quality fats like olive, MCT, coconut, and hemp oil while adhering to "THE KETO WAY" to maintain my state of ketosis.
Vitamins
8
Gamma-tocopherol in cancer research
Gamma-Tocopherol: A Comprehensive Review of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties.
Most Relevant Research
We examined the effects of gamma-tocopherol, a major form of vitamin E, on cancer treatment and prevention. This powerful antioxidant is noted for its ability to combat oxidative stress, which plays a significant role in the development and progression of various cancers.
In several studies, we observed that gamma-tocopherol not only neutralizes harmful reactive oxygen species but also exhibits anti-inflammatory properties. These characteristics help reduce chronic inflammation tied to cancer risks. Furthermore, it has shown the potential to inhibit tumor growth, induce cancer cell death, and restrict blood vessel formation that tumors require to grow.
Specifically, findings indicated that gamma-tocopherol is particularly effective in cancers such as prostate, lung, and colon. With promising results from both preclinical and clinical trials, there is a growing interest in how this natural compound can be beneficial in cancer management.
While we noted excellent tolerance at normal doses, it’s essential to consider careful monitoring at higher levels to avoid any adverse effects. Hence, we believe that ongoing research and advancements in drug delivery methods could further enhance its effectiveness.
In several studies, we observed that gamma-tocopherol not only neutralizes harmful reactive oxygen species but also exhibits anti-inflammatory properties. These characteristics help reduce chronic inflammation tied to cancer risks. Furthermore, it has shown the potential to inhibit tumor growth, induce cancer cell death, and restrict blood vessel formation that tumors require to grow.
Specifically, findings indicated that gamma-tocopherol is particularly effective in cancers such as prostate, lung, and colon. With promising results from both preclinical and clinical trials, there is a growing interest in how this natural compound can be beneficial in cancer management.
While we noted excellent tolerance at normal doses, it’s essential to consider careful monitoring at higher levels to avoid any adverse effects. Hence, we believe that ongoing research and advancements in drug delivery methods could further enhance its effectiveness.
8.8
Antitumour properties
Most Useful Review
Vitamin K2 is vital for calcium absorption and blood clotting. It redirects calcium from the blood to bone tissue, which is crucial for bone and dental health. Notably, in 2006, its antitumour properties were discovered, showing benefits against certain cancers, including lung, pancreatic, bladder, and rectal. Ongoing studies continue to explore its potential.
Melatonin
9.5
Safe for cancer recovery
Most Useful Review
I’ve been taking melatonin for years without fail, especially recommended after my breast cancer 20 years ago. It ensures I have a good night’s sleep and is safe without causing addiction.
9.5
Immune system support
Most Useful Review
I purchased this for my mother, who has cancer and was struggling to sleep. After starting the melatonin, she reported much better sleep. I plan to buy some for myself next!
Zinc
8
Zinc's role in cancer immunity
Implanted Microneedles Loaded with Sparfloxacin and Zinc-Manganese Sulfide Nanoparticles Activates Immunity for Postoperative Triple-Negative Breast Cancer to Prevent Recurrence and Metastasis.
Most Relevant Research
We investigated the impact of zinc, specifically when combined with manganese sulfide, on preventing the recurrence of triple-negative breast cancer (TNBC) post-surgery. This approach involved microneedles loaded with Sparfloxacin and zinc-manganese sulfide, which were targeted for localized treatment to enhance immune response while also addressing wound infection risk.
Through this innovative design, we observed that the zinc-manganese formulation not only displayed strong antimicrobial and antibiofilm properties but also played a role in promoting immune activation. This led to significant reductions in tumor growth and lung metastasis, alongside improved wound healing. The therapy activated key immune pathways, particularly the cGAS-STING pathway, which further bolstered the body’s ability to fight cancer cells.
Overall, the results suggest that zinc, paired with manganese, can provide an effective strategy for enhancing both local and systemic immune responses. This has promising implications for preventing cancer recurrence, particularly in challenging cases like TNBC, paving the way for potential new treatment approaches in oncology.
Through this innovative design, we observed that the zinc-manganese formulation not only displayed strong antimicrobial and antibiofilm properties but also played a role in promoting immune activation. This led to significant reductions in tumor growth and lung metastasis, alongside improved wound healing. The therapy activated key immune pathways, particularly the cGAS-STING pathway, which further bolstered the body’s ability to fight cancer cells.
Overall, the results suggest that zinc, paired with manganese, can provide an effective strategy for enhancing both local and systemic immune responses. This has promising implications for preventing cancer recurrence, particularly in challenging cases like TNBC, paving the way for potential new treatment approaches in oncology.
9.5
Reduces cancer risk
Most Useful Review
Zinc effectively stimulates the immune system and shortens the duration of colds. It aids vision and reduces the risk of age-related macular degeneration. As an antioxidant, zinc plays a vital role in reducing oxidative stress and therefore lowers cancer risk.
Protein
9
METTL14 modifications impact AML
Specific sDMA modifications on the RGG/RG motif of METTL14 regulate its function in AML.
Most Relevant Research
We explored how specific changes to the METTL14 protein affect cancer, particularly in acute myeloid leukemia (AML). By examining the RG-rich region of METTL14, we discovered that a special form of arginine methylation called symmetric dimethylation, specifically at positions R425 and R445, plays a vital role in enhancing its function.
Our research revealed that this modification not only improves the activity of the METTL3:METTL14 complex but also influences which genes get expressed in cancer cells. We found that the presence of symmetric dimethylarginines helps the complex deposit a crucial chemical mark, known as m6A, on RNA, which is essential for the regulation of gene activity.
Furthermore, we conducted a series of experiments that indicated a potential therapeutic angle in targeting the METTL3 and PRMT5 proteins. When both are inhibited, we observed a significant drop in the expression of genes important for AML cell growth, hinting at new possibilities for treating this challenging cancer. Overall, this study highlights the intricate relationship between protein modifications and cancer biology, emphasizing the potential for more targeted approaches in therapy.
Our research revealed that this modification not only improves the activity of the METTL3:METTL14 complex but also influences which genes get expressed in cancer cells. We found that the presence of symmetric dimethylarginines helps the complex deposit a crucial chemical mark, known as m6A, on RNA, which is essential for the regulation of gene activity.
Furthermore, we conducted a series of experiments that indicated a potential therapeutic angle in targeting the METTL3 and PRMT5 proteins. When both are inhibited, we observed a significant drop in the expression of genes important for AML cell growth, hinting at new possibilities for treating this challenging cancer. Overall, this study highlights the intricate relationship between protein modifications and cancer biology, emphasizing the potential for more targeted approaches in therapy.
8.8
Supports cancer treatment
Most Useful Review
I ordered pumpkin seeds for the first time and found them to be of excellent quality. They are small, clean, and loved by my children. I give them daily due to their beneficial composition, which includes high protein and healthy fats. Regular consumption is believed to help combat cancer, boost immunity, and improve overall health without side effects. Additionally, they may assist with various ailments and are rich in essential vitamins and minerals. I really enjoyed them and will definitely repurchase.
Ip 6
9
Myo-inositol affects prostate cancer cells
Proteomic Analysis of Anticancer Effect of Myo-inositol in Human Prostate Cancer (DU-145) Cell Line.
Most Relevant Research
We investigated the potential benefits of Myo-inositol, a naturally occurring sugar alcohol, on DU-145 prostate cancer cells. By treating these cancer cells with various doses of Myo-inositol, we determined its half-maximal inhibitory concentration (IC50) using a simple method that measures cell viability.
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
8.8
Effective for animals
Most Useful Review
Cell Forte Max3 has worked wonders for animals with cancer. I’ve seen it help my hedgehog with liver cancer and a friend’s horse with skin cancer. It also aided my dog with autoimmune issues. After one month, a fatty tumour I had shrank by half. This product is exceedingly safe, and I’ve been a fan since 1990.
Probiotics
5
Gut bacteria influence chemotherapy outcomes
Metagenome association study of the gut microbiome revealed biomarkers linked to chemotherapy outcomes in locally advanced and advanced lung cancer.
Most Relevant Research
We explored the connection between gut bacteria and chemotherapy outcomes in lung cancer patients. By studying stool samples from 64 individuals with locally advanced and advanced lung cancer, we compared the gut microbiota of those who responded to treatment with those who did not.
Notably, certain bacteria, like Streptococcus mutans, were more abundant in responders, while Leuconostoc lactis was associated with nonresponders. This suggests that the makeup of our gut microbiome may influence how well chemotherapy works in these patients, offering insights for more personalized treatment strategies.
Notably, certain bacteria, like Streptococcus mutans, were more abundant in responders, while Leuconostoc lactis was associated with nonresponders. This suggests that the makeup of our gut microbiome may influence how well chemotherapy works in these patients, offering insights for more personalized treatment strategies.
8.8
Improved intestinal health
Most Useful Review
I am pleasantly surprised. After taking 2 or 3 tablets daily for ten days, I noticed positive changes. My usual morning stool now comes out around 2 pm. Previously, I experienced painful bloating after lunch, but that discomfort has disappeared, and my bowel movements are much smoother. After my mother died of colon cancer, I feared inheriting that issue, so I started this to improve my gut health. I look forward to continuing this and hope it will benefit both my intestinal and skin health over the next three months.
Vitamin D3
7
Vitamin D3’s role in cancer metabolism
Isotope tracing-assisted chip-based solid-phase extraction mass spectrometry for monitoring metabolic changes and vitamin D3 regulation in cells.
Most Relevant Research
We explored how vitamin D3 impacts cancer metabolism through an innovative chip-based solid-phase extraction mass spectrometry method. This approach allowed us to closely analyze the metabolic changes in both normal liver cells and cancer cells, providing a real-time view of how these processes work. With this technology, we could detect various metabolites at incredibly low concentrations, helping us form a clearer picture of cellular metabolism.
Our observations highlighted significant differences in metabolism between normal cells and cancerous ones, specifically noting increased glycolytic activity and higher lactate production in cancer cells. When we treated the cancer cells with 1,25-dihydroxyvitamin D3 (the active form of vitamin D3), we found that it suppressed glucose uptake and altered metabolic activity in one type of cancer cell, HCT116. This finding suggests that vitamin D3 could play a regulatory role in how cancer cells manage their energy and metabolize nutrients.
Overall, our study sheds light on the metabolic changes associated with cancer and points to vitamin D3 as a potential modulator of these processes. The insights gained could be valuable for developing new cancer therapies and understanding metabolic diseases better.
Our observations highlighted significant differences in metabolism between normal cells and cancerous ones, specifically noting increased glycolytic activity and higher lactate production in cancer cells. When we treated the cancer cells with 1,25-dihydroxyvitamin D3 (the active form of vitamin D3), we found that it suppressed glucose uptake and altered metabolic activity in one type of cancer cell, HCT116. This finding suggests that vitamin D3 could play a regulatory role in how cancer cells manage their energy and metabolize nutrients.
Overall, our study sheds light on the metabolic changes associated with cancer and points to vitamin D3 as a potential modulator of these processes. The insights gained could be valuable for developing new cancer therapies and understanding metabolic diseases better.
8.8
Supports cancer treatment
Most Useful Review
Vitamine D is crucial for bone health and has anti-cancer benefits. If your 25 (OH) D level is 20 or less, it's advisable to start with 5000 IU daily. For levels 21-30, take 2,000 IU, and if it's 31-40, take 1000 IU daily. After three months, retest. The optimal level is 50-70. Vitamin D supplementation raises levels effectively without odour. Sunlight aids production, but sunscreen can hinder it. This supplement has improved my health significantly. Happy shopping!
Omega 3
7
Effects of fatty acids on cancer
Investigation of the Effects of Polyunsaturated Fatty Acid Ratios in Human SH-SY5Y Cells by Methods.
Most Relevant Research
We aimed to understand how different ratios of omega-3 and omega-6 fatty acids, particularly eicosapentaenoic acid (EPA), influence neuroblastoma cells. This type of cancer is known as one of the most aggressive forms affecting children.
During our study, we treated human neuroblastoma cells (SH-SY5Y) with various ratios of omega-3 and omega-6 fatty acids for 48 and 72 hours. To measure the effectiveness of these treatments, we looked at cell viability, levels of oxidative stress, and apoptosis—essentially, did the treatments help kill the cancer cells?
Our findings revealed that while increasing the omega-3 to omega-6 ratio led to lower levels of reactive oxygen species, it also reduced the apoptosis rates in these cells. Although we observed some effects with omega fatty acids, there was no significant evidence supporting the idea that eicosapentaenoic acid alone would provide a strong anticancer benefit.
This research marks an important investigation into how fatty acids interact with cancer cells, although the results indicate that taking omega-3 fatty acids might not be a cure or significant treatment for neuroblastoma on their own.
During our study, we treated human neuroblastoma cells (SH-SY5Y) with various ratios of omega-3 and omega-6 fatty acids for 48 and 72 hours. To measure the effectiveness of these treatments, we looked at cell viability, levels of oxidative stress, and apoptosis—essentially, did the treatments help kill the cancer cells?
Our findings revealed that while increasing the omega-3 to omega-6 ratio led to lower levels of reactive oxygen species, it also reduced the apoptosis rates in these cells. Although we observed some effects with omega fatty acids, there was no significant evidence supporting the idea that eicosapentaenoic acid alone would provide a strong anticancer benefit.
This research marks an important investigation into how fatty acids interact with cancer cells, although the results indicate that taking omega-3 fatty acids might not be a cure or significant treatment for neuroblastoma on their own.
8.8
Cancer prevention benefits
Most Useful Review
"Mega" omega is wonderful fish oil of excellent quality! It contains a natural fish oil concentrate rich in polyunsaturated fatty acids, which dramatically lower cholesterol levels, supporting cardiovascular health. Omega 3 is noted for slowing tumour development and is effective in preventing cancer. It aids in skin disease treatment and improves healing. This supplement also normalises digestion and fat metabolism, alleviates arthritis pain, and is essential for brain activity. Recommended dosage is 3-4 capsules daily with meals.
Echinacea
9
Echinacea modulates gut health in cancer
Echinacea purpurea polysaccharide intervene in hepatocellular carcinoma via modulation of gut microbiota to inhibit TLR4/NF-κB pathway.
Most Relevant Research
We investigated how Echinacea purpurea polysaccharide (EPP) might help in fighting hepatocellular carcinoma, a common type of liver cancer. Our findings showed that EPP not only reduced liver damage caused by cancer but also helped in slowing down cancer cell growth and promoting their death, a process known as apoptosis.
An interesting aspect of our study was how EPP influenced gut microbiota. After treatment with EPP, we observed a significant increase in beneficial bacteria that produce propionic and butyric acids. These changes in gut microbes led to strengthening the intestinal barrier, which is crucial for keeping harmful substances like lipopolysaccharides (LPS) from leaking into the bloodstream. By controlling LPS leakage, EPP helped reduce inflammation and hindered the TLR4/NF-κB signaling pathway that cancer cells often exploit to survive.
On a molecular level, our metabolomics analysis revealed that EPP treatment downregulated certain metabolic pathways associated with tumor growth while enhancing butyrate metabolism, which is linked to healthier cellular functions. Overall, our research highlights EPP's potential to combat liver cancer through beneficial modifications to the gut microbiome and consequent impacts on inflammation and cancer cell survival.
An interesting aspect of our study was how EPP influenced gut microbiota. After treatment with EPP, we observed a significant increase in beneficial bacteria that produce propionic and butyric acids. These changes in gut microbes led to strengthening the intestinal barrier, which is crucial for keeping harmful substances like lipopolysaccharides (LPS) from leaking into the bloodstream. By controlling LPS leakage, EPP helped reduce inflammation and hindered the TLR4/NF-κB signaling pathway that cancer cells often exploit to survive.
On a molecular level, our metabolomics analysis revealed that EPP treatment downregulated certain metabolic pathways associated with tumor growth while enhancing butyrate metabolism, which is linked to healthier cellular functions. Overall, our research highlights EPP's potential to combat liver cancer through beneficial modifications to the gut microbiome and consequent impacts on inflammation and cancer cell survival.
8.8
Effective immunity boost
Most Useful Review
Excellent! The echinacea plant is well-known for enhancing immunity and combating cancer cells. It's particularly useful for those with immunodeficiency. I obtained it for my mother and noticed an improvement in her condition. I highly recommend this brand as its products are very effective and the results are remarkable.
Garlic
7
Garlic's dual effects in cancer
Mechanism of Action and Interaction of Garlic Extract and Established Therapeutics in Prostate Cancer.
Most Relevant Research
We explored the effects of garlic extract (GE) on prostate cancer (PCa) cells to understand how it might work alongside established cancer therapies. A notable case mentioned a patient who managed to maintain stable prostate-specific antigen (PSA) levels for over 14 years with daily GE intake after being diagnosed with PCa, which piqued our curiosity about GE's potential benefits.
In our study, we looked at how GE impacts different prostate cells, including healthy cells and various PCa cell lines. We observed that GE reduced the growth of LNCaP and PC3 cancer cells while showing mixed results with VCaP cells. This indicates that while garlic could slow cancer cell proliferation in some cases, it doesn't work uniformly across all types of cancer cells.
Additionally, we investigated how GE interacts with common cancer treatments like chemotherapy and androgen deprivation therapy. Surprisingly, the combination of GE with these therapies diminished their effectiveness, possibly due to an increase in a specific enzyme in cancer cells that affects drug metabolism. This finding suggests that while GE may offer some anti-cancer properties, its use should be carefully monitored when combined with established cancer treatments to avoid unintended consequences.
In our study, we looked at how GE impacts different prostate cells, including healthy cells and various PCa cell lines. We observed that GE reduced the growth of LNCaP and PC3 cancer cells while showing mixed results with VCaP cells. This indicates that while garlic could slow cancer cell proliferation in some cases, it doesn't work uniformly across all types of cancer cells.
Additionally, we investigated how GE interacts with common cancer treatments like chemotherapy and androgen deprivation therapy. Surprisingly, the combination of GE with these therapies diminished their effectiveness, possibly due to an increase in a specific enzyme in cancer cells that affects drug metabolism. This finding suggests that while GE may offer some anti-cancer properties, its use should be carefully monitored when combined with established cancer treatments to avoid unintended consequences.
9.5
Strengthens immunity
Most Useful Review
Garlic is excellent for the gut, enhancing enzyme secretion and digestion, while strengthening the immune system and improving cardiovascular health. It lowers cholesterol, aids high blood pressure, and reduces cancer risks. I firmly believe in garlic’s healing properties.
Fish Oil
7
Effects of fatty acids on cancer
Investigation of the Effects of Polyunsaturated Fatty Acid Ratios in Human SH-SY5Y Cells by Methods.
Most Relevant Research
We aimed to understand how different ratios of omega-3 and omega-6 fatty acids, particularly eicosapentaenoic acid (EPA), influence neuroblastoma cells. This type of cancer is known as one of the most aggressive forms affecting children.
During our study, we treated human neuroblastoma cells (SH-SY5Y) with various ratios of omega-3 and omega-6 fatty acids for 48 and 72 hours. To measure the effectiveness of these treatments, we looked at cell viability, levels of oxidative stress, and apoptosis—essentially, did the treatments help kill the cancer cells?
Our findings revealed that while increasing the omega-3 to omega-6 ratio led to lower levels of reactive oxygen species, it also reduced the apoptosis rates in these cells. Although we observed some effects with omega fatty acids, there was no significant evidence supporting the idea that eicosapentaenoic acid alone would provide a strong anticancer benefit.
This research marks an important investigation into how fatty acids interact with cancer cells, although the results indicate that taking omega-3 fatty acids might not be a cure or significant treatment for neuroblastoma on their own.
During our study, we treated human neuroblastoma cells (SH-SY5Y) with various ratios of omega-3 and omega-6 fatty acids for 48 and 72 hours. To measure the effectiveness of these treatments, we looked at cell viability, levels of oxidative stress, and apoptosis—essentially, did the treatments help kill the cancer cells?
Our findings revealed that while increasing the omega-3 to omega-6 ratio led to lower levels of reactive oxygen species, it also reduced the apoptosis rates in these cells. Although we observed some effects with omega fatty acids, there was no significant evidence supporting the idea that eicosapentaenoic acid alone would provide a strong anticancer benefit.
This research marks an important investigation into how fatty acids interact with cancer cells, although the results indicate that taking omega-3 fatty acids might not be a cure or significant treatment for neuroblastoma on their own.
8.3
Cancer prevention
Most Useful Review
Omega is of high quality, increases immunity, has a pleasant scent, and offers great benefits. I believe it helps prevent cancer and comes in a tightly sealed package. It serves as a strong antioxidant and cleanses the body.
Elderberry
4
Elderberry extract shows limited benefits
Anthocyanin-Rich Berry Extracts Affect SN-38-Induced Response: A Comparison of Non-Tumorigenic HCEC-1CT and HCT116 Colon Carcinoma Cells.
Most Relevant Research
We aimed to understand if anthocyanin-rich extracts from elderberry could protect healthy cells from the harmful effects of a cancer drug called SN-38, while still helping to fight cancer cells. To do this, we tested extracts from elderberry, bilberry, blackberry, and black currant on two cell types: non-tumorigenic human intestinal epithelial cells and colon cancer cells.
In our findings, blackberry extract stood out for its strong cytotoxic effects, impacting both healthy and cancerous cells. Surprisingly, in healthy cells, blackberry reduced levels of certain harmful DNA complexes caused by the drug, but did not lessen the DNA damage inflicted by SN-38.
This leads us to an important conclusion: anthocyanins from elderberry and other berries may interfere with the effectiveness of cancer treatments rather than offering protective benefits for healthy tissues. The evidence showed no significant protective role for elderberry extract in this context.
In our findings, blackberry extract stood out for its strong cytotoxic effects, impacting both healthy and cancerous cells. Surprisingly, in healthy cells, blackberry reduced levels of certain harmful DNA complexes caused by the drug, but did not lessen the DNA damage inflicted by SN-38.
This leads us to an important conclusion: anthocyanins from elderberry and other berries may interfere with the effectiveness of cancer treatments rather than offering protective benefits for healthy tissues. The evidence showed no significant protective role for elderberry extract in this context.
9.5
Cancer fighter
Most Useful Review
Very excellent; it is regarded as a cancer fighter and an antioxidant.