Ubiquinol shows mixed effectsEffect of Ubiquinol Intake on Defecation Frequency and Stool Form: A Prospective, Double-Blinded, Randomized Control Study.
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We conducted a study to examine how coenzyme Q10, in its reduced form known as ubiquinol, might affect constipation in individuals dealing with daily abdominal discomfort. Using a robust, double-blind, randomized control design, we enlisted forty-one patients who experienced either constipation or diarrhea. Participants were split evenly into two groups, with one receiving 150 mg of ubiquinol each day for twelve weeks, while the other group received a placebo.
Over the course of the study, we had participants keep a daily diary to monitor their defecation frequency and the consistency of their stools, following the Bristol Stool Form Scale. After twelve weeks, we noticed some interesting changes. The ubiquinol group reported a slight decrease in defecation frequency, averaging -0.1 times a day, while the placebo group saw an increase of +0.3 times a day. However, there was no significant change in stool form for the ubiquinol group, while the placebo group’s scores improved.
On the brighter side, we also found that the ubiquinol group experienced a notable improvement in their overall health perception, reflected in their quality of life scores. In contrast, there were no significant changes in the placebo group’s scores. Overall, our findings suggest that ubiquinol may modify bowel habits and enhance the quality of life for patients suffering from abdominal distress, despite the small drop in defecation frequency among those taking it.