Best Supplements for Cancer

Products best matching Cancer

Product	Science Score	User Score
Ester C
American Health, Ester-C with Citrus Bioflavonoids, 1,000 mg, 120 Vegetarian Tablets	9	8.6
9 Vitamin C enhances immune response Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. He X, Wang Q, Cheng X, Wang W, Li Y, et al. Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. Cell. 2025. doi:10.1016/j.cell.2025.01.043 We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1. By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells. Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C. 10 Cancer support benefits Most Useful Review I consistently assert that these vitamins are essential and should be a staple in every household. My experience with ayherb has proven their worth multiple times. Vitamin C aids the body in producing collagen, assimilating chondroprotectors, and fighting free radicals, while enhancing immunity. It protects against winter colds and summer oedema. The Nobel laureate Linus Pauling demonstrated its ability to destroy cancer stem cells. Caring for loved ones includes ensuring they receive these essential vitamins. Wishing you and your family good health.
American Health, Ester-C with Citrus Bioflavonoids, 1,000 mg, 90 Capsules	9	8.3
9 Vitamin C enhances immune response Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. He X, Wang Q, Cheng X, Wang W, Li Y, et al. Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. Cell. 2025. doi:10.1016/j.cell.2025.01.043 We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1. By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells. Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C. 9 Vital for immune system Most Useful Review It works! I find this Ester-C absorbs more readily and significantly supports my immune system after cancer. I make sure to keep it stocked at home to combat colds, and I can increase the dosage without upsetting my stomach.
Ascorbic Acid
NOW Foods, Vitamin C Crystals, 1 lb (454 g)	9	8.4
9 Vitamin C enhances immune response Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. He X, Wang Q, Cheng X, Wang W, Li Y, et al. Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. Cell. 2025. doi:10.1016/j.cell.2025.01.043 We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1. By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells. Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C. 9 Boosted immunity Most Useful Review 1 people found this helpful Now Vitamin C is excellent. I’ve taken vitamin C for years but found this at a better price. It’s powdered ascorbic acid, which absorbs well. The sour taste is manageable when mixed with water. Since I take 4000 mg thrice daily post-meals, I’ve noticed fewer nosebleeds and colds. My stamina has improved, my skin is clearer, and I recover quickly from damage. If you have a sensitive stomach, start gradually. Vitamin C is essential.
NOW Foods, C-1000, 250 Tablets	9	8.4
9 Vitamin C enhances immune response Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. He X, Wang Q, Cheng X, Wang W, Li Y, et al. Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. Cell. 2025. doi:10.1016/j.cell.2025.01.043 We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1. By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells. Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C. 9 Natural medicine benefits Most Useful Review 1 people found this helpful Few people realise that this is the best natural medicine! I haven’t been ill for years; I can’t even remember what a runny nose feels like. It’s remarkable to consider taking 200g per day, especially with serious conditions like cancer. I took 30g daily for candida, and it worked perfectly. Our bodies are well-equipped for all illnesses but occasionally need our assistance, and that’s where this comes in. I avoid medications, only taking vitamins, and everything is well.
Doctor's Best, Vitamin C , 1,000 mg, 120 Veggie Caps	9	8
9 Vitamin C enhances immune response Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. He X, Wang Q, Cheng X, Wang W, Li Y, et al. Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. Cell. 2025. doi:10.1016/j.cell.2025.01.043 We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1. By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells. Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C. 9 Best for immunity Most Useful Review In my opinion, this is the best vitamin C supplement available for my immunity, quality, and potency. Being a breast cancer survivor, I need the largest package with the best ingredients.
Alpha Lipoic Acid
Doctor's Best, Alpha-Lipoic Acid 600, 600 mg, 180 Veggie Caps	9	8.2
9 Alpha-lipoic acid aids recovery Randomized controlled trial of bromelain and alpha-lipoic acid in breast conservative surgery. Sgaramella LI, Pasculli A, Moschetta M, Puntillo F, Dicillo P, et al. Randomized controlled trial of bromelain and alpha-lipoic acid in breast conservative surgery. Sci Rep. 2025;15:4899. doi:10.1038/s41598-025-86651-2 We conducted a thorough analysis to determine how alpha-lipoic acid, in combination with other supplements, affects early complications like edema and seroma following breast-conserving surgery (BCS). Our study was structured as a double-blind, randomized, placebo-controlled trial involving 114 participants over a span of three years. Participants were divided into three groups, with one group receiving a mix of Casperome™-Boswellia Phytosome and bromelain along with alpha-lipoic acid, while the other groups received either bromelain with a placebo or just a placebo. Over a period of 30 days, we gathered data on the effectiveness of these treatments. Our findings revealed that the combination of bromelain and alpha-lipoic acid significantly reduced the incidence of edema and seroma compared to the placebo. Specifically, after one month, we observed marked improvements in patients who received the active treatment. This research highlights the potential therapeutic benefits of alpha-lipoic acid, especially when used with other agents, in managing early complications that can follow breast surgery. Although it’s important to note that the specific isolating effects of alpha-lipoic acid on its own were challenging to determine, the results offer a promising glimpse into its use in surgical recovery. 9 Promotes recovery Most Useful Review 8 people found this helpful I brought this for my dad who has cancer. It offers powerful antioxidants and aids in cell renewal. I pray for my father's recovery.
Vitamin C
NOW Foods, C-500 With Rose Hips, 250 Tablets	9	8.2
9 Vitamin C enhances immune response Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. He X, Wang Q, Cheng X, Wang W, Li Y, et al. Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. Cell. 2025. doi:10.1016/j.cell.2025.01.043 We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1. By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells. Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C. 9 Survivor advocate Most Useful Review This sustained release Vitamin C has kept me healthy for over a year! As a cancer survivor with no immune system, I recommend it to everyone and even share orders with my family.
Garden of Life, Vitamin Code, RAW Vitamin C, 60 Vegan Capsules	9	8.1
9 Vitamin C enhances immune response Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. He X, Wang Q, Cheng X, Wang W, Li Y, et al. Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. Cell. 2025. doi:10.1016/j.cell.2025.01.043 We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1. By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells. Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C. 9 Cancer prevention Most Useful Review Vitamin C is a potent antioxidant that combats free radicals, prolonging youth and bolstering health while protecting against cancer. It is essential for protein synthesis, muscle gain, and wound healing. Vitamin C helps remove toxins and oversees adrenal gland function, vital for hormone production and managing stress. Deficiency leads to symptoms like bleeding gums and slow healing. I recommend Garden of Life's Vitamin Code; its unique whole food formula is well absorbed and supports the immune system, with profits aiding children in need.
NOW Foods, C-1000 with Bioflavonoids, 250 Veg Capsules	9	7.9
9 Vitamin C enhances immune response Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. He X, Wang Q, Cheng X, Wang W, Li Y, et al. Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. Cell. 2025. doi:10.1016/j.cell.2025.01.043 We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1. By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells. Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C. 9 Essential for therapy Most Useful Review 6 people found this helpful Vitamin C is remarkably effective, especially in cancer therapy. Many people underestimate the importance of bioflavonoids which are essential for its effectiveness. These capsules have proven beneficial, showing significant efficacy in combating cancer cells.
NOW Foods, C-1000, 250 Tablets	9	7.8
9 Vitamin C enhances immune response Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. He X, Wang Q, Cheng X, Wang W, Li Y, et al. Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. Cell. 2025. doi:10.1016/j.cell.2025.01.043 We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1. By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells. Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C. 8 Cancer progress halted Most Useful Review 2 people found this helpful Best choice! It is an essential supplement for my husband, who doesn't enjoy sour fruits. I discovered my cancer last year, and I believe this supplement has inhibited its progression. I am pleased to take it as it has a time-release formula. Furthermore, it is quite affordable in Japan. Thank you!
Magnesium
Doctor's Best, High Absorption Magnesium, 200 mg, 120 Tablets, (100 mg per Tablet)	8.6	8.5
8 Magnesium alloy inhibits cancer growth Biodegradable Mg-1%Ca alloy inhibits the growth of cervical cancer. Ouyang Y, Cao L, Zhao Q, Yang W, Lin C. Biodegradable Mg-1%Ca alloy inhibits the growth of cervical cancer. Biomed Mater. 2025. doi:10.1088/1748-605X/adb2cc We explored how magnesium alloy, particularly a variant containing 1% calcium, impacts cervical cancer cells. Our investigation revealed that this alloy has promising antitumor properties which could pave the way for new treatments. In our experiments, we tested the effects of the Mg-1%Ca alloy both in laboratory settings and in living organisms. This alloy was found to release magnesium ions and hydroxide ions more slowly than expected. We observed that it effectively inhibited the growth of cervical cancer cells, specifically SiHa and HeLa cell lines. Additionally, the presence of the alloy induced apoptosis, or programmed cell death, in the cancer cells, disrupted their structural integrity, and hindered their ability to migrate and invade other tissues. Importantly, the Mg-1%Ca alloy was seen to influence key molecular pathways, specifically the MAPK/ERK signaling pathway, which plays a role in cancer cell proliferation. With these results, it's evident that magnesium alloy could serve as a useful adjunct to current cervical cancer therapies, potentially helping to prevent both cancer growth and metastasis. 10 Recommended for cancer Most Useful Review I've been taking this for a few months now; it’s my second purchase. As a cancer patient, my magnesium levels were low, and my doctor advised long-term use. I found this product on IHerb and can highly recommend it.
NOW Foods, Magnesium Citrate, 400 mg, 120 Veg Capsules (133 mg per Capsule)	8.6	8.1
8 Magnesium alloy inhibits cancer growth Biodegradable Mg-1%Ca alloy inhibits the growth of cervical cancer. Ouyang Y, Cao L, Zhao Q, Yang W, Lin C. Biodegradable Mg-1%Ca alloy inhibits the growth of cervical cancer. Biomed Mater. 2025. doi:10.1088/1748-605X/adb2cc We explored how magnesium alloy, particularly a variant containing 1% calcium, impacts cervical cancer cells. Our investigation revealed that this alloy has promising antitumor properties which could pave the way for new treatments. In our experiments, we tested the effects of the Mg-1%Ca alloy both in laboratory settings and in living organisms. This alloy was found to release magnesium ions and hydroxide ions more slowly than expected. We observed that it effectively inhibited the growth of cervical cancer cells, specifically SiHa and HeLa cell lines. Additionally, the presence of the alloy induced apoptosis, or programmed cell death, in the cancer cells, disrupted their structural integrity, and hindered their ability to migrate and invade other tissues. Importantly, the Mg-1%Ca alloy was seen to influence key molecular pathways, specifically the MAPK/ERK signaling pathway, which plays a role in cancer cell proliferation. With these results, it's evident that magnesium alloy could serve as a useful adjunct to current cervical cancer therapies, potentially helping to prevent both cancer growth and metastasis. 7.5 Relieves constipation Most Useful Review I've just started using it, and it seems to be effective for my constipation due to colon cancer.
Solgar, Magnesium with Vitamin B6, 250 Tablets	8.1	8.3
9 Vitamin B6 pathway affects cancer survival Vitamin B6 Pathway Maintains Glioblastoma Cell Survival in 3D Spheroid Cultures. Moosa NY, Azeem SA, Lodge JK, Cheung W, Ahmed SU. Vitamin B6 Pathway Maintains Glioblastoma Cell Survival in 3D Spheroid Cultures. Int J Mol Sci. 2024;25. doi:10.3390/ijms251910428 We explored the role of the vitamin B6 pathway in glioblastoma, a particularly aggressive form of brain cancer. Through a detailed analysis involving various cell cultures, we noted significant changes in vitamin B6-related metabolites when comparing 3D spheroid cultures to traditional 2D monolayers. This discovery led us to investigate further the implications of these findings for cancer cell survival. We found that using hydralazine, a compound that effectively reduces vitamin B6 levels, triggered cell death in 3D GBM spheroid cultures. Our results suggest that targeting the vitamin B6 pathway could offer a new avenue for developing treatments for this challenging cancer. This innovative approach highlights the necessity of understanding metabolic processes within tumor environments for creating effective therapies. 9 Helps with constipation Most Useful Review This is a wonderful supplement to ease the side effects of chemotherapy! Honestly, chemotherapy causes many side effects, including constipation. My husband is a cancer patient who, even with a great diet, struggled with side effects. Laxatives are often filled with chemicals and can take days to work. The key component in these laxatives is MAGNESIUM. After taking these, he returned to “normal” within a few days. As chemotherapy depletes vital vitamins, the combination of B6 and magnesium is excellent for absorption. I also take them now, and my leg cramps have gone. Many individuals do not consume enough magnesium, crucial for bone health. This product is perfect for seniors; the small tablets are smooth and easy to swallow.
Sodium Ascorbate
NOW Foods, Sodium Ascorbate Powder, 8 oz (227 g)	9	8.1
9 Vitamin C enhances immune response Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. He X, Wang Q, Cheng X, Wang W, Li Y, et al. Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. Cell. 2025. doi:10.1016/j.cell.2025.01.043 We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1. By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells. Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C. 10 Breast cancer support Most Useful Review 3 people found this helpful My wife is living with breast cancer, which is being managed partly by using sodium ascorbate mixed with sterile water for injection, infused every other day. It's a pure product that has proven effective in keeping her condition stable. Thank you for helping to keep her alive!
Enzymes
NOW Foods, Nattokinase, 100 mg, 120 Veg Capsules	8.8	8.2
9 Nattokinase may inhibit liver cancer Nattokinase Crude Extract Inhibits Hepatocellular Carcinoma Growth in Mice. Yan Y, Wang Y, Qian J, Wu S, Ji Y, et al. Nattokinase Crude Extract Inhibits Hepatocellular Carcinoma Growth in Mice. J Microbiol Biotechnol. 2019;29:1281. doi:10.4014/jmb.1812.12058 We assessed the impact of nattokinase crude extract (NCE) on liver cancer, specifically hepatocellular carcinoma (HCC), using mouse models. Mice receiving NCE exhibited a 31% survival rate improvement and reduced tumor sizes, as indicated by imaging and pathology evaluations. Additionally, NCE led to decreased levels of several cancer markers. Overall, these findings suggest that nattokinase may positively influence liver cancer outcomes in this model. 7.5 Helps blood cancer Most Useful Review 12 people found this helpful Wonderful! We use this instead of aspirin. My husband has a blood cancer that increases the viscosity of his blood, making it thicker, and this is certainly helping.
Doctor's Best, Nattokinase, 2,000 FUs, 270 Veggie Caps	8.8	8.1
9 Nattokinase may inhibit liver cancer Nattokinase Crude Extract Inhibits Hepatocellular Carcinoma Growth in Mice. Yan Y, Wang Y, Qian J, Wu S, Ji Y, et al. Nattokinase Crude Extract Inhibits Hepatocellular Carcinoma Growth in Mice. J Microbiol Biotechnol. 2019;29:1281. doi:10.4014/jmb.1812.12058 We assessed the impact of nattokinase crude extract (NCE) on liver cancer, specifically hepatocellular carcinoma (HCC), using mouse models. Mice receiving NCE exhibited a 31% survival rate improvement and reduced tumor sizes, as indicated by imaging and pathology evaluations. Additionally, NCE led to decreased levels of several cancer markers. Overall, these findings suggest that nattokinase may positively influence liver cancer outcomes in this model. 9 Cancer cell destruction Most Useful Review 69 people found this helpful I discovered Nattokinase after struggling with thrombosis. It improves oxygen delivery, helps remove toxins, and can destroy cancer cell plaque, allowing immune cells to identify them. The benefits include improved nutrient absorption, reduced joint pain, and better lymphatic drainage. I recommend consulting a physician before use, especially if you take other medications.
Doctor's Best, High Absorption CoQ10 with BioPerine®, 100 mg, 120 Veggie Caps	8.8	8
9 CoQ10 mitigates chemobrain effects Coenzyme Q10 ameliorates cyclophosphamide-induced chemobrain by repressing neuronal apoptosis and preserving hippocampal neurogenesis: Mechanistic roles of Wnt/ β-catenin signaling pathway. Hussein Z, Michel HE, El-Naga RN, El-Demerdash E, Mantawy EM. Coenzyme Q10 ameliorates cyclophosphamide-induced chemobrain by repressing neuronal apoptosis and preserving hippocampal neurogenesis: Mechanistic roles of Wnt/ β-catenin signaling pathway. Neurotoxicology. 2024;105:21. doi:10.1016/j.neuro.2024.08.003 We explored the potential benefits of Coenzyme Q10 (CoQ10) on cancer patients dealing with a condition commonly referred to as "Chemobrain," which is associated with treatment using the chemotherapy drug cyclophosphamide (CYP). In our study, male rats were given a daily dose of CoQ10 for ten days, while they also received a single dose of CYP to model the effects of chemotherapy on cognition and motor skills. The findings were promising. CoQ10 not only helped counteract cognitive and motor dysfunctions triggered by CYP but also showed significant neuroprotective effects. Behavioral tests demonstrated improvements, and histopathological analysis confirmed that CoQ10 reduced brain damage linked to oxidative stress caused by CYP. This micronutrient effectively restored levels of the antioxidant enzyme catalase and lowered harmful substances like malondialdehyde. Furthermore, CoQ10 appeared to inhibit neuronal apoptosis, or cell death, by balancing expressions of key proteins involved in the process. It supported neurogenesis in the hippocampus by increasing important growth factors. Most notably, CoQ10 activated the Wnt/β-catenin signaling pathway, which is crucial for brain health and development. Overall, our study highlights how CoQ10 may offer a multi-faceted approach to mitigating the adverse effects of chemotherapy on cognitive function, bolstering both brain protection and regeneration. 9 Supports immunity Most Useful Review This powerful supplement is highly recommended by doctors to boost the immunity of cancer patients.
Doctor's Best, High Absorption CoQ10 with BioPerine®, 60 Veggie Caps	8.8	8
9 CoQ10 mitigates chemobrain effects Coenzyme Q10 ameliorates cyclophosphamide-induced chemobrain by repressing neuronal apoptosis and preserving hippocampal neurogenesis: Mechanistic roles of Wnt/ β-catenin signaling pathway. Hussein Z, Michel HE, El-Naga RN, El-Demerdash E, Mantawy EM. Coenzyme Q10 ameliorates cyclophosphamide-induced chemobrain by repressing neuronal apoptosis and preserving hippocampal neurogenesis: Mechanistic roles of Wnt/ β-catenin signaling pathway. Neurotoxicology. 2024;105:21. doi:10.1016/j.neuro.2024.08.003 We explored the potential benefits of Coenzyme Q10 (CoQ10) on cancer patients dealing with a condition commonly referred to as "Chemobrain," which is associated with treatment using the chemotherapy drug cyclophosphamide (CYP). In our study, male rats were given a daily dose of CoQ10 for ten days, while they also received a single dose of CYP to model the effects of chemotherapy on cognition and motor skills. The findings were promising. CoQ10 not only helped counteract cognitive and motor dysfunctions triggered by CYP but also showed significant neuroprotective effects. Behavioral tests demonstrated improvements, and histopathological analysis confirmed that CoQ10 reduced brain damage linked to oxidative stress caused by CYP. This micronutrient effectively restored levels of the antioxidant enzyme catalase and lowered harmful substances like malondialdehyde. Furthermore, CoQ10 appeared to inhibit neuronal apoptosis, or cell death, by balancing expressions of key proteins involved in the process. It supported neurogenesis in the hippocampus by increasing important growth factors. Most notably, CoQ10 activated the Wnt/β-catenin signaling pathway, which is crucial for brain health and development. Overall, our study highlights how CoQ10 may offer a multi-faceted approach to mitigating the adverse effects of chemotherapy on cognitive function, bolstering both brain protection and regeneration. 7.5 Supports heart health Most Useful Review 1 people found this helpful My husband and I took this product to support heart health. There were some slight pains, but I read that coenzyme assists in heart function and slows ageing. I have been taking one capsule daily with food for a month. Coenzyme Q10 absorbs better with dietary fats at breakfast or lunch, helping to avoid sleep disturbances. I feel better after a month of use, noting benefits such as improved heart function and reduced cancer cell degeneration. Coenzyme Q10 boosts cellular energy, aids immune function, and enhances oxygen uptake, thus preserving skin beauty and youth.
Doctor's Best, High Potency Serrapeptase, 120,000 SPU, 270 Veggie Caps	N/A	8.6
9 Effective cancer treatment Most Useful Review 162 people found this helpful My favourite dietary supplement! Serrapeptase is one of the safest and most effective anti-inflammatory drugs, gently breaking down fibrous formations. It has helped with conditions related to cancer, promotes normal blood flow, and cleanses toxins. I have taken it regularly, and it feels like a nanoscalpel with no side effects. I appreciate its benefits and will keep buying it. 9 Removes cancer cells Most Useful Review 2 people found this helpful I've taken serrapeptase twice daily since last October for hip arthritis. It has notably reduced my pain. I also give it to my mother, who has cancer. It assists in removing dead cancer cells, so I highly recommend it, alongside available research.
Vitamin Bs
Solgar, Folate, 1,333 mcg, 100 Tablets (1,333 mcg DFE per Tablet)	8.5	8.5
9 Folate-enhanced nanoparticle effectiveness Cell membrane-inspired chitosan nanoparticles for prolonged circulation and tumor-targeted drug delivery. Xie M, Zhao J, Feng X, Gao X, Cheng W, et al. Cell membrane-inspired chitosan nanoparticles for prolonged circulation and tumor-targeted drug delivery. Int J Biol Macromol. 2025;304:140934. doi:10.1016/j.ijbiomac.2025.140934 We explored innovative ways to improve cancer treatment by using folate-targeted nanoparticles. The study focused on the development of chitosan nanoparticles that mimic cell membranes, enhancing their ability to evade the immune system and prolong circulation in the body. By integrating folate, a nutrient known to target cancer cells, we hoped to increase the effectiveness of drug delivery directly to tumors. Our findings revealed that these folate-targeted nanoparticles showed a remarkable capacity to be absorbed by breast cancer cells, specifically increasing uptake efficiency by five to six times compared to nanoparticles without folate. This was a significant boost, showcasing the potential of using folate as a guiding factor for cancer treatment. Furthermore, the study demonstrated that these nanoparticles remained in the bloodstream for much longer, with their half-life extended from roughly 2.7 hours to nearly 13 hours. This means they can circulate longer and potentially reach tumors more effectively. Ultimately, our research aims to pave the way for more efficient cancer therapies, highlighting how leveraging folate in nanoparticle design may provide a promising strategy in the fight against cancer. 9 Cancer protection Most Useful Review 37 people found this helpful Folic acid is essential, especially for those preparing for pregnancy or with a deficiency. It offers powerful protection against cancer. This bottle contains the ideal form of folic acid for our bodies!
NOW Foods, Flush-Free Niacin, 250 mg, 180 Veg Capsules	8.3	8.2
9 Myo-inositol affects prostate cancer cells Proteomic Analysis of Anticancer Effect of Myo-inositol in Human Prostate Cancer (DU-145) Cell Line. Islam MJ, Muntaha S, Masum MM, Nowshin S, Salam S, et al. Proteomic Analysis of Anticancer Effect of Myo-inositol in Human Prostate Cancer (DU-145) Cell Line. Asian Pac J Cancer Prev. 2024;25:4447. doi:10.31557/APJCP.2024.25.12.4447 We investigated the potential benefits of Myo-inositol, a naturally occurring sugar alcohol, on DU-145 prostate cancer cells. By treating these cancer cells with various doses of Myo-inositol, we determined its half-maximal inhibitory concentration (IC50) using a simple method that measures cell viability. Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth. Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment. Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC). 7.5 Significant effects Most Useful Review Flushing-Free Niacin B3 contains quality ingredients that benefit joints, dilate blood vessels, lower blood pressure, improve skin spots, reduce skin cancer, increase cell energy, and alleviate eczema. The effects are significant.
Jarrow Formulas, Vegan Methyl B-12 & Methyl Folate, Extra Strength, Lemon, 100 Chewable Tablets	7.9	8.3
9 Vitamin B6 pathway affects cancer survival Vitamin B6 Pathway Maintains Glioblastoma Cell Survival in 3D Spheroid Cultures. Moosa NY, Azeem SA, Lodge JK, Cheung W, Ahmed SU. Vitamin B6 Pathway Maintains Glioblastoma Cell Survival in 3D Spheroid Cultures. Int J Mol Sci. 2024;25. doi:10.3390/ijms251910428 We explored the role of the vitamin B6 pathway in glioblastoma, a particularly aggressive form of brain cancer. Through a detailed analysis involving various cell cultures, we noted significant changes in vitamin B6-related metabolites when comparing 3D spheroid cultures to traditional 2D monolayers. This discovery led us to investigate further the implications of these findings for cancer cell survival. We found that using hydralazine, a compound that effectively reduces vitamin B6 levels, triggered cell death in 3D GBM spheroid cultures. Our results suggest that targeting the vitamin B6 pathway could offer a new avenue for developing treatments for this challenging cancer. This innovative approach highlights the necessity of understanding metabolic processes within tumor environments for creating effective therapies. 8 Essential for pregnancy Most Useful Review Excellent! Methylfolate ((6S)-5-methyltetrahydrofolate) is a highly effective active form of folic acid. Quatrefolic® is a fourth-generation production technology. ✅ Folic acid deficiency can cause brain dysfunction, colon cancer, and heart disease! Vitamin C during pregnancy is vital for both mother and child. Sufficient folate in a pregnant woman's diet can reduce the risk of developmental defects in the brain and spinal cord. Additionally, Vitamin C is crucial for all cell growth processes, including supporting immunity and heart function.
Iron
Solgar, Gentle Iron®, 25 mg, 90 Vegetable Capsules	9	8
9 SPIO improves lymph node detection Use of superparamagnetic iron oxide for sentinel lymph node detection following neoadjuvant systemic therapy. A systematic review and meta-analysis. Boland MR, Pantiora E, Rutherford C, Evoy D, Prichard RS, et al. Use of superparamagnetic iron oxide for sentinel lymph node detection following neoadjuvant systemic therapy. A systematic review and meta-analysis. Eur J Surg Oncol. 2025;51:109684. doi:10.1016/j.ejso.2025.109684 We explored the effectiveness of superparamagnetic iron oxide (SPIO) in detecting sentinel lymph nodes in breast cancer patients who had undergone neoadjuvant systemic therapy before surgery. This study included a systematic review of multiple databases and focused on comparing SPIO to the standard methods involving radioisotope and blue dye. Our findings highlight that SPIO successfully identified sentinel lymph nodes in about 98.1% of cases, while the standard method achieved a detection rate of 94.6%. When examining the number of lymph nodes retrieved, SPIO demonstrated superior performance, with an average of 2.26 nodes detected compared to 1.86 with the conventional approach. The overall quality of the studies reviewed was considered good, indicating that we can reliably say SPIO can be safely and effectively adopted in clinical practice for these patients. This suggests a promising alternative in medical settings, where identifying lymph nodes accurately is crucial for treatment planning. 9 Significant improvement Most Useful Review 6 people found this helpful These pills are excellent. My father is a cancer patient and was incredibly weak with a hemoglobin level of just 50 in August. After two months of taking these pills, his hemoglobin rose to 106. I’m really pleased with the results.
Selenium
Solgar, Selenium, Yeast-Free, 200 mcg, 250 Tablets	8.3	8.3
9.5 Selenium drug shows selective toxicity Selenium Electrophilic Center Responsive to Biological Electron Donors for Efficient Chemotherapy. Qin X, Guo J, Li H, He H, Cai F, et al. Selenium Electrophilic Center Responsive to Biological Electron Donors for Efficient Chemotherapy. Adv Sci (Weinh). 2025. doi:10.1002/advs.202412062 We examined how a selenium-containing drug, known as RuSe, targets cancer cells while sparing normal cells. This innovative approach leverages the unique properties of selenium, specifically its electrophilic center, to create oxidative stress within cancer cells. By shuttling electrons from biological electron donors, the drug activates a sequence of events detrimental to cancer survival. The results were striking; we found that the rate of electron transfer at the selenium site is significantly higher in cancer cells compared to normal cells—1.81 times greater, to be precise. This selective action leads to a lethal effect, with the drug being 14.98 times more harmful to cancer cells than to their healthy counterparts. We observed that the generation of superoxide anions from this process causes DNA damage and triggers the p53 signaling pathway, which enhances the drug's effectiveness in killing cancer cells. Our findings offer an exciting new avenue for crafting chemotherapeutic agents that can be both efficient and less toxic. By exploiting the special properties of selenium, we open the door to more intelligent and targeted cancer therapies that could reduce side effects for patients. 7.5 Essential for cancer Most Useful Review 62 people found this helpful A remarkable mineral in the best form and dosage. This is a yeastless selenium, which is vital for those prone to candidal infections. The optimum dosage for preventing selenium deficiency is 200 mg per day. Those with immunosuppression or heavy metal poisoning should take 400 mg daily without fear of side effects. It must be taken with vitamin E, as these antioxidants complement each other. Selenium is irreplaceable in the fight against cancer, providing protection against heart and artery diseases. It has an anti-inflammatory effect, beneficial for arthritis. Although results should not be expected quickly, relief comes within 3-4 months. It’s advisable to take it alongside other important antioxidants.
NOW Foods, Selenium, 200 mcg, 180 Veg Capsules	8.3	8.2
9.5 Selenium drug shows selective toxicity Selenium Electrophilic Center Responsive to Biological Electron Donors for Efficient Chemotherapy. Qin X, Guo J, Li H, He H, Cai F, et al. Selenium Electrophilic Center Responsive to Biological Electron Donors for Efficient Chemotherapy. Adv Sci (Weinh). 2025. doi:10.1002/advs.202412062 We examined how a selenium-containing drug, known as RuSe, targets cancer cells while sparing normal cells. This innovative approach leverages the unique properties of selenium, specifically its electrophilic center, to create oxidative stress within cancer cells. By shuttling electrons from biological electron donors, the drug activates a sequence of events detrimental to cancer survival. The results were striking; we found that the rate of electron transfer at the selenium site is significantly higher in cancer cells compared to normal cells—1.81 times greater, to be precise. This selective action leads to a lethal effect, with the drug being 14.98 times more harmful to cancer cells than to their healthy counterparts. We observed that the generation of superoxide anions from this process causes DNA damage and triggers the p53 signaling pathway, which enhances the drug's effectiveness in killing cancer cells. Our findings offer an exciting new avenue for crafting chemotherapeutic agents that can be both efficient and less toxic. By exploiting the special properties of selenium, we open the door to more intelligent and targeted cancer therapies that could reduce side effects for patients. 9 Boosts cancer defence Most Useful Review 191 people found this helpful This mineral supplement is vital for immunity and thyroid health. Selenium acts as a powerful antioxidant, combating atherosclerosis, cancer, infertility risk, and chronic fatigue. I recommend it for improving brain function and reducing cardiovascular disease risks.
NOW Foods, Selenium, 100 mcg, 100 Tablets	8.3	8
9.5 Selenium drug shows selective toxicity Selenium Electrophilic Center Responsive to Biological Electron Donors for Efficient Chemotherapy. Qin X, Guo J, Li H, He H, Cai F, et al. Selenium Electrophilic Center Responsive to Biological Electron Donors for Efficient Chemotherapy. Adv Sci (Weinh). 2025. doi:10.1002/advs.202412062 We examined how a selenium-containing drug, known as RuSe, targets cancer cells while sparing normal cells. This innovative approach leverages the unique properties of selenium, specifically its electrophilic center, to create oxidative stress within cancer cells. By shuttling electrons from biological electron donors, the drug activates a sequence of events detrimental to cancer survival. The results were striking; we found that the rate of electron transfer at the selenium site is significantly higher in cancer cells compared to normal cells—1.81 times greater, to be precise. This selective action leads to a lethal effect, with the drug being 14.98 times more harmful to cancer cells than to their healthy counterparts. We observed that the generation of superoxide anions from this process causes DNA damage and triggers the p53 signaling pathway, which enhances the drug's effectiveness in killing cancer cells. Our findings offer an exciting new avenue for crafting chemotherapeutic agents that can be both efficient and less toxic. By exploiting the special properties of selenium, we open the door to more intelligent and targeted cancer therapies that could reduce side effects for patients. 9 Anti-cancer properties Most Useful Review 214 people found this helpful Selenium is recognised for its potent anti-cancer properties and is effective in preventing various diseases. Its roles in DNA repair and enhancing immune functions, along with antioxidant benefits, imply selenium's significant role in cancer prevention. Studies indicate that a daily intake of 200 mcg can notably lower the risk of colorectal, prostate, and lung cancers while reducing overall cancer-related mortality.
Life Extension, Super Selenium Complex & Vitamin E, 200 mcg, 100 Vegetarian Capsules	8.1	7.9
9.5 Selenium drug shows selective toxicity Selenium Electrophilic Center Responsive to Biological Electron Donors for Efficient Chemotherapy. Qin X, Guo J, Li H, He H, Cai F, et al. Selenium Electrophilic Center Responsive to Biological Electron Donors for Efficient Chemotherapy. Adv Sci (Weinh). 2025. doi:10.1002/advs.202412062 We examined how a selenium-containing drug, known as RuSe, targets cancer cells while sparing normal cells. This innovative approach leverages the unique properties of selenium, specifically its electrophilic center, to create oxidative stress within cancer cells. By shuttling electrons from biological electron donors, the drug activates a sequence of events detrimental to cancer survival. The results were striking; we found that the rate of electron transfer at the selenium site is significantly higher in cancer cells compared to normal cells—1.81 times greater, to be precise. This selective action leads to a lethal effect, with the drug being 14.98 times more harmful to cancer cells than to their healthy counterparts. We observed that the generation of superoxide anions from this process causes DNA damage and triggers the p53 signaling pathway, which enhances the drug's effectiveness in killing cancer cells. Our findings offer an exciting new avenue for crafting chemotherapeutic agents that can be both efficient and less toxic. By exploiting the special properties of selenium, we open the door to more intelligent and targeted cancer therapies that could reduce side effects for patients. 7.5 Defence against cancer Most Useful Review 5 people found this helpful Selenium is indispensable for maintaining health, based on its role in protecting against cancer through its antioxidant activity. A daily intake has notably increased my immune response and offers protection against harmful metals.
Country Life, Selenium, 100 mcg, 180 Tablets	8.3	7.6
9.5 Selenium drug shows selective toxicity Selenium Electrophilic Center Responsive to Biological Electron Donors for Efficient Chemotherapy. Qin X, Guo J, Li H, He H, Cai F, et al. Selenium Electrophilic Center Responsive to Biological Electron Donors for Efficient Chemotherapy. Adv Sci (Weinh). 2025. doi:10.1002/advs.202412062 We examined how a selenium-containing drug, known as RuSe, targets cancer cells while sparing normal cells. This innovative approach leverages the unique properties of selenium, specifically its electrophilic center, to create oxidative stress within cancer cells. By shuttling electrons from biological electron donors, the drug activates a sequence of events detrimental to cancer survival. The results were striking; we found that the rate of electron transfer at the selenium site is significantly higher in cancer cells compared to normal cells—1.81 times greater, to be precise. This selective action leads to a lethal effect, with the drug being 14.98 times more harmful to cancer cells than to their healthy counterparts. We observed that the generation of superoxide anions from this process causes DNA damage and triggers the p53 signaling pathway, which enhances the drug's effectiveness in killing cancer cells. Our findings offer an exciting new avenue for crafting chemotherapeutic agents that can be both efficient and less toxic. By exploiting the special properties of selenium, we open the door to more intelligent and targeted cancer therapies that could reduce side effects for patients. 7.5 Prevents cancer development Most Useful Review 5 people found this helpful Selenium fortifies the immune system and acts as a potent antioxidant, shielding cells from free radicals, which can be exacerbated by factors like smoking and stress. This mineral is linked to cardiovascular disease prevention, and studies indicate that a 50% increase in blood selenium correlates with a 24% drop in coronary artery disease. Its antitumor properties against lung and breast cancer are well-documented, and selenium is essential for proper thyroid function.
Zinc
NOW Foods, Zinc Picolinate, 50 mg, 60 Veg Capsules (50 mg per Capsule)	8.2	8.4
8 Zinc's role in cancer immunity cancer cells outcompete macrophages for microenvironmental zinc to drive immunotherapy resistance. Buj R, Cole AR, Danielson J, Xu J, Hurd D, et al. cancer cells outcompete macrophages for microenvironmental zinc to drive immunotherapy resistance. bioRxiv. 2025. doi:10.1101/2025.02.08.637227 We explored how zinc levels impact cancer cells and immune function, particularly focusing on macrophages, which are crucial for our body’s defense against tumors. Our research revealed that cancer cells often have decreased expression of specific genes tied to immune response, and this links to resistance against therapies designed to unblock immune checkpoints. By upregulating a zinc importer known as SLC39A9, these cancer cells manage to hoard zinc for themselves, leaving the surrounding tumor microenvironment (TME) depleted of this vital nutrient. This competition for zinc results in macrophages becoming zinc-starved, which diminishes their ability to perform essential tasks like engulfing and destroying cancer cells. Interestingly, we found that when we replenished zinc levels in the TME—through a dietary intervention—these macrophages could regain their pro-phagocytic function. This change significantly improved the response of certain tumors to immunotherapy treatments. Notably, T cells weren’t required for this transformation, indicating that macrophages alone play a pivotal role. Our results are clinically relevant, showing that cancer patients with reduced zinc levels in their body tend to experience worse outcomes. Overall, we identified a new mechanism by which cancer cells can disrupt immune function, highlighting zinc’s critical role in both tumor environments and immunotherapy effectiveness. 9 Reduces cancer risk Most Useful Review 3 people found this helpful Zinc effectively stimulates the immune system and shortens the duration of colds. It aids vision and reduces the risk of age-related macular degeneration. As an antioxidant, zinc plays a vital role in reducing oxidative stress and therefore lowers cancer risk.
Nature's Way, Zinc Chelate, 30 mg, 100 Capsules	8.2	8.2
8 Zinc's role in cancer immunity cancer cells outcompete macrophages for microenvironmental zinc to drive immunotherapy resistance. Buj R, Cole AR, Danielson J, Xu J, Hurd D, et al. cancer cells outcompete macrophages for microenvironmental zinc to drive immunotherapy resistance. bioRxiv. 2025. doi:10.1101/2025.02.08.637227 We explored how zinc levels impact cancer cells and immune function, particularly focusing on macrophages, which are crucial for our body’s defense against tumors. Our research revealed that cancer cells often have decreased expression of specific genes tied to immune response, and this links to resistance against therapies designed to unblock immune checkpoints. By upregulating a zinc importer known as SLC39A9, these cancer cells manage to hoard zinc for themselves, leaving the surrounding tumor microenvironment (TME) depleted of this vital nutrient. This competition for zinc results in macrophages becoming zinc-starved, which diminishes their ability to perform essential tasks like engulfing and destroying cancer cells. Interestingly, we found that when we replenished zinc levels in the TME—through a dietary intervention—these macrophages could regain their pro-phagocytic function. This change significantly improved the response of certain tumors to immunotherapy treatments. Notably, T cells weren’t required for this transformation, indicating that macrophages alone play a pivotal role. Our results are clinically relevant, showing that cancer patients with reduced zinc levels in their body tend to experience worse outcomes. Overall, we identified a new mechanism by which cancer cells can disrupt immune function, highlighting zinc’s critical role in both tumor environments and immunotherapy effectiveness. 7.5 Supports cancer treatment Most Useful Review Good zinc! For those with zinc deficiency, especially men planning to have children, it's crucial. Zinc acts as an antioxidant that neutralises free radicals, preventing cancer, and stimulates blood production while promoting collagen synthesis for wound healing. The quality is excellent, with a high daily content, and the capsules are conveniently sized.
NOW Foods, Zinc, 50 mg, 250 Tablets	8.2	8.2
8 Zinc's role in cancer immunity cancer cells outcompete macrophages for microenvironmental zinc to drive immunotherapy resistance. Buj R, Cole AR, Danielson J, Xu J, Hurd D, et al. cancer cells outcompete macrophages for microenvironmental zinc to drive immunotherapy resistance. bioRxiv. 2025. doi:10.1101/2025.02.08.637227 We explored how zinc levels impact cancer cells and immune function, particularly focusing on macrophages, which are crucial for our body’s defense against tumors. Our research revealed that cancer cells often have decreased expression of specific genes tied to immune response, and this links to resistance against therapies designed to unblock immune checkpoints. By upregulating a zinc importer known as SLC39A9, these cancer cells manage to hoard zinc for themselves, leaving the surrounding tumor microenvironment (TME) depleted of this vital nutrient. This competition for zinc results in macrophages becoming zinc-starved, which diminishes their ability to perform essential tasks like engulfing and destroying cancer cells. Interestingly, we found that when we replenished zinc levels in the TME—through a dietary intervention—these macrophages could regain their pro-phagocytic function. This change significantly improved the response of certain tumors to immunotherapy treatments. Notably, T cells weren’t required for this transformation, indicating that macrophages alone play a pivotal role. Our results are clinically relevant, showing that cancer patients with reduced zinc levels in their body tend to experience worse outcomes. Overall, we identified a new mechanism by which cancer cells can disrupt immune function, highlighting zinc’s critical role in both tumor environments and immunotherapy effectiveness. 9 Prevents cancer development Most Useful Review Zinc is vital for producing approximately 100 enzymes in the body. It acts as an antioxidant, neutralising free radicals and preventing cancer's progression. Zinc also stimulates blood production and promotes collagen synthesis, essential for wound healing.
Jarrow Formulas, Vegan Zinc Balance, 100 Veggie Capsules	8.2	8.1
8 Zinc's role in cancer immunity cancer cells outcompete macrophages for microenvironmental zinc to drive immunotherapy resistance. Buj R, Cole AR, Danielson J, Xu J, Hurd D, et al. cancer cells outcompete macrophages for microenvironmental zinc to drive immunotherapy resistance. bioRxiv. 2025. doi:10.1101/2025.02.08.637227 We explored how zinc levels impact cancer cells and immune function, particularly focusing on macrophages, which are crucial for our body’s defense against tumors. Our research revealed that cancer cells often have decreased expression of specific genes tied to immune response, and this links to resistance against therapies designed to unblock immune checkpoints. By upregulating a zinc importer known as SLC39A9, these cancer cells manage to hoard zinc for themselves, leaving the surrounding tumor microenvironment (TME) depleted of this vital nutrient. This competition for zinc results in macrophages becoming zinc-starved, which diminishes their ability to perform essential tasks like engulfing and destroying cancer cells. Interestingly, we found that when we replenished zinc levels in the TME—through a dietary intervention—these macrophages could regain their pro-phagocytic function. This change significantly improved the response of certain tumors to immunotherapy treatments. Notably, T cells weren’t required for this transformation, indicating that macrophages alone play a pivotal role. Our results are clinically relevant, showing that cancer patients with reduced zinc levels in their body tend to experience worse outcomes. Overall, we identified a new mechanism by which cancer cells can disrupt immune function, highlighting zinc’s critical role in both tumor environments and immunotherapy effectiveness. 9 Protects against cancer Most Useful Review 4 people found this helpful Zinc resembles a superhero in reducing oxidative stress and risks of serious diseases like cancer. It is essential, especially during global health crises. I take it to bolster my immunity and help protect against infections, asserting its significance in both seasonal illnesses and Covid-19. I wholeheartedly endorse this supplement!
Quercetin
Jarrow Formulas, Vegan Quercetin, 500 mg, 100 Veggie Capsules	8.2	8.4
9 Quercetin's role against colorectal cancer Structure-activity relationship analysis of mono-methylated quercetins by comprehensive MS/MS analysis and anti-proliferative efficacy in human colorectal cancer cells. Han S, Yi YW, Kim H, Lee MY, Choi H, et al. Structure-activity relationship analysis of mono-methylated quercetins by comprehensive MS/MS analysis and anti-proliferative efficacy in human colorectal cancer cells. Biomed Pharmacother. 2025;184:117930. doi:10.1016/j.biopha.2025.117930 We aimed to understand how quercetin and its derivatives, especially mono-methylated quercetins (MQs), might help in treating colorectal cancer. Using advanced techniques like tandem mass spectrometry, we identified specific structural features of these flavonoids that could enhance their anti-cancer activities. Our findings showed that methylation at specific positions on the quercetin molecule significantly improved its ability to fight cancer cells. Notably, 3-O-methylquercetin and 4'-O-methylquercetin were particularly effective. These compounds caused cancer cells to stop dividing and triggered programmed cell death, also known as apoptosis. We observed that these MQs worked through several mechanisms, such as inducing oxidative stress, disrupting mitochondrial function, and inactivating cancer-related signaling pathways—all while being non-toxic to normal human colon cells. This makes them promising candidates for cancer therapy, especially for patients with colorectal cancer. Ultimately, our research revealed that small modifications in flavonoid structures could lead to significant improvements in their anti-cancer effectiveness, providing a path for developing targeted treatments for colorectal cancer. 9 Cancer resistance Most Useful Review 56 people found this helpful Quercetin is a unique and irreplaceable substance that effectively fights against various cancers, including breast and pancreatic cancer. It enhances vascular tone, combats atherosclerosis, allergies, and regulates blood pressure. Additionally, it helps in reducing inflammation and boosts immune response. However, it is vital to know the correct dosage, as excessive intake may be harmful.
Life Extension, Optimized Quercetin, 250 mg, 60 Vegetarian Capsules	8.2	8.2
9 Quercetin's role against colorectal cancer Structure-activity relationship analysis of mono-methylated quercetins by comprehensive MS/MS analysis and anti-proliferative efficacy in human colorectal cancer cells. Han S, Yi YW, Kim H, Lee MY, Choi H, et al. Structure-activity relationship analysis of mono-methylated quercetins by comprehensive MS/MS analysis and anti-proliferative efficacy in human colorectal cancer cells. Biomed Pharmacother. 2025;184:117930. doi:10.1016/j.biopha.2025.117930 We aimed to understand how quercetin and its derivatives, especially mono-methylated quercetins (MQs), might help in treating colorectal cancer. Using advanced techniques like tandem mass spectrometry, we identified specific structural features of these flavonoids that could enhance their anti-cancer activities. Our findings showed that methylation at specific positions on the quercetin molecule significantly improved its ability to fight cancer cells. Notably, 3-O-methylquercetin and 4'-O-methylquercetin were particularly effective. These compounds caused cancer cells to stop dividing and triggered programmed cell death, also known as apoptosis. We observed that these MQs worked through several mechanisms, such as inducing oxidative stress, disrupting mitochondrial function, and inactivating cancer-related signaling pathways—all while being non-toxic to normal human colon cells. This makes them promising candidates for cancer therapy, especially for patients with colorectal cancer. Ultimately, our research revealed that small modifications in flavonoid structures could lead to significant improvements in their anti-cancer effectiveness, providing a path for developing targeted treatments for colorectal cancer. 9 Reduces cancer risk Most Useful Review 7 people found this helpful Quercetin is a powerful antioxidant that has a strong healing effect on the body. It addresses efforts to combat diseases such as stroke and heart attack. The anti-inflammatory properties of quercetin benefit blood vessels, lower blood pressure, and help prevent atherosclerosis. Its antioxidant action reduces the risk of cardiovascular disease. Including foods, particularly fruits and vegetables, rich in quercetin in your diet can significantly lower the risk of dangerous diseases. Quercetin possesses strong anti-tumour properties and can inhibit the growth of new cancer cells. In larger doses, it may even eliminate cancer cells.
Life Extension, Bio-Quercetin, 30 Vegetarian Capsules	8.2	7.9
9 Quercetin's role against colorectal cancer Structure-activity relationship analysis of mono-methylated quercetins by comprehensive MS/MS analysis and anti-proliferative efficacy in human colorectal cancer cells. Han S, Yi YW, Kim H, Lee MY, Choi H, et al. Structure-activity relationship analysis of mono-methylated quercetins by comprehensive MS/MS analysis and anti-proliferative efficacy in human colorectal cancer cells. Biomed Pharmacother. 2025;184:117930. doi:10.1016/j.biopha.2025.117930 We aimed to understand how quercetin and its derivatives, especially mono-methylated quercetins (MQs), might help in treating colorectal cancer. Using advanced techniques like tandem mass spectrometry, we identified specific structural features of these flavonoids that could enhance their anti-cancer activities. Our findings showed that methylation at specific positions on the quercetin molecule significantly improved its ability to fight cancer cells. Notably, 3-O-methylquercetin and 4'-O-methylquercetin were particularly effective. These compounds caused cancer cells to stop dividing and triggered programmed cell death, also known as apoptosis. We observed that these MQs worked through several mechanisms, such as inducing oxidative stress, disrupting mitochondrial function, and inactivating cancer-related signaling pathways—all while being non-toxic to normal human colon cells. This makes them promising candidates for cancer therapy, especially for patients with colorectal cancer. Ultimately, our research revealed that small modifications in flavonoid structures could lead to significant improvements in their anti-cancer effectiveness, providing a path for developing targeted treatments for colorectal cancer. 7.5 Promotes detoxification Most Useful Review 5 people found this helpful Quercetin addresses arthritis, asthma and other inflammatory conditions while effectively combating viral infections. By boosting the immune system, it promotes detoxification enzymes that eliminate carcinogens, which is vital in various types of cancer. Quercetin also supports cerebral circulation, notably in Alzheimer's disease, and helps prevent skin and eye aging.
NOW Foods, Quercetin with Bromelain, 120 Veg Capsules	8.2	7.4
9 Quercetin's role against colorectal cancer Structure-activity relationship analysis of mono-methylated quercetins by comprehensive MS/MS analysis and anti-proliferative efficacy in human colorectal cancer cells. Han S, Yi YW, Kim H, Lee MY, Choi H, et al. Structure-activity relationship analysis of mono-methylated quercetins by comprehensive MS/MS analysis and anti-proliferative efficacy in human colorectal cancer cells. Biomed Pharmacother. 2025;184:117930. doi:10.1016/j.biopha.2025.117930 We aimed to understand how quercetin and its derivatives, especially mono-methylated quercetins (MQs), might help in treating colorectal cancer. Using advanced techniques like tandem mass spectrometry, we identified specific structural features of these flavonoids that could enhance their anti-cancer activities. Our findings showed that methylation at specific positions on the quercetin molecule significantly improved its ability to fight cancer cells. Notably, 3-O-methylquercetin and 4'-O-methylquercetin were particularly effective. These compounds caused cancer cells to stop dividing and triggered programmed cell death, also known as apoptosis. We observed that these MQs worked through several mechanisms, such as inducing oxidative stress, disrupting mitochondrial function, and inactivating cancer-related signaling pathways—all while being non-toxic to normal human colon cells. This makes them promising candidates for cancer therapy, especially for patients with colorectal cancer. Ultimately, our research revealed that small modifications in flavonoid structures could lead to significant improvements in their anti-cancer effectiveness, providing a path for developing targeted treatments for colorectal cancer. 7.5 Improved wellbeing Most Useful Review 664 people found this helpful I have multiple sclerosis, but this supplement has been stunningly effective. At 52, my health has improved significantly. Quercetin, a powerful antioxidant, along with bromelain, is helping my treatment against cancer. I only relied on these supplements and avoided antibiotics throughout my recovery. I consistently take them for ongoing health and quality of life.
Spirulina
NOW Foods, Certified Organic Spirulina, Double Strength, 1,000 mg, 120 Tablets	8.1	8.4
9 Spirulina shows promise in cancer treatment Combining In Vitro, In Vivo, and Network Pharmacology Assays to Identify Targets and Molecular Mechanisms of Spirulina-Derived Biomolecules against Breast Cancer. Hassanin SO, Hegab AMM, Mekky RH, Said MA, Khalil MG, et al. Combining In Vitro, In Vivo, and Network Pharmacology Assays to Identify Targets and Molecular Mechanisms of Spirulina-Derived Biomolecules against Breast Cancer. Mar Drugs. 2024;22. doi:10.3390/md22070328 We investigated how Spirulina might combat breast cancer using an animal model and a human cell line. When given to animals, Spirulina increased antioxidants and reduced tumor growth. It caused changes at the cellular level, promoting cancer cell death and impacting key growth pathways. The study identified several compounds in Spirulina that target specific proteins, suggesting it could play a significant role in breast cancer treatment. 9 Cancer treatment benefits Most Useful Review 290 people found this helpful Spirulina is a source of plant protein and B vitamins, particularly B12, making it beneficial for vegetarians. While it aids in weight loss, healthy eating and exercise are still essential. Spirulina boosts the immune system, helps with anemia by increasing hemoglobin, and has anti-cancer properties through phycocyanin, which can inhibit cancer cell growth. It is vital to use it in moderation and consider its effects on the body.
Nutrex Hawaii, Pure Hawaiian Spirulina, Powder, 16 oz (454 g)	8.1	8.1
9 Spirulina shows promise in cancer treatment Combining In Vitro, In Vivo, and Network Pharmacology Assays to Identify Targets and Molecular Mechanisms of Spirulina-Derived Biomolecules against Breast Cancer. Hassanin SO, Hegab AMM, Mekky RH, Said MA, Khalil MG, et al. Combining In Vitro, In Vivo, and Network Pharmacology Assays to Identify Targets and Molecular Mechanisms of Spirulina-Derived Biomolecules against Breast Cancer. Mar Drugs. 2024;22. doi:10.3390/md22070328 We investigated how Spirulina might combat breast cancer using an animal model and a human cell line. When given to animals, Spirulina increased antioxidants and reduced tumor growth. It caused changes at the cellular level, promoting cancer cell death and impacting key growth pathways. The study identified several compounds in Spirulina that target specific proteins, suggesting it could play a significant role in breast cancer treatment. 9 Energy boost Most Useful Review 9 people found this helpful My interest in spirulina was piqued by its unique characteristics. Phycocyanin, found only in spirulina, is reported to inhibit cancer cell growth. Introducing spirulina into my diet has improved my skin's health and metabolic balance. I've chosen Nutrex Hawaii's spirulina for its quality and lack of unpleasant odour. Mixing it in smoothies has been delightful, and I was surprised by the pleasant taste. The first effect I noticed was a surge of energy. I recommend this product; it has seamlessly fit into my diet, and I expect it will benefit others as well.
NOW Foods, Certified Organic Spirulina Powder, 1 lb (454 g)	8.1	7.9
9 Spirulina shows promise in cancer treatment Combining In Vitro, In Vivo, and Network Pharmacology Assays to Identify Targets and Molecular Mechanisms of Spirulina-Derived Biomolecules against Breast Cancer. Hassanin SO, Hegab AMM, Mekky RH, Said MA, Khalil MG, et al. Combining In Vitro, In Vivo, and Network Pharmacology Assays to Identify Targets and Molecular Mechanisms of Spirulina-Derived Biomolecules against Breast Cancer. Mar Drugs. 2024;22. doi:10.3390/md22070328 We investigated how Spirulina might combat breast cancer using an animal model and a human cell line. When given to animals, Spirulina increased antioxidants and reduced tumor growth. It caused changes at the cellular level, promoting cancer cell death and impacting key growth pathways. The study identified several compounds in Spirulina that target specific proteins, suggesting it could play a significant role in breast cancer treatment.
Inositol
NOW Foods, Inositol Capsules, 500 mg, 100 Veg Capsules	8.3	8.2
9 Myo-inositol affects prostate cancer cells Proteomic Analysis of Anticancer Effect of Myo-inositol in Human Prostate Cancer (DU-145) Cell Line. Islam MJ, Muntaha S, Masum MM, Nowshin S, Salam S, et al. Proteomic Analysis of Anticancer Effect of Myo-inositol in Human Prostate Cancer (DU-145) Cell Line. Asian Pac J Cancer Prev. 2024;25:4447. doi:10.31557/APJCP.2024.25.12.4447 We investigated the potential benefits of Myo-inositol, a naturally occurring sugar alcohol, on DU-145 prostate cancer cells. By treating these cancer cells with various doses of Myo-inositol, we determined its half-maximal inhibitory concentration (IC50) using a simple method that measures cell viability. Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth. Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment. Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC). 9 Menstrual cycle restoration Most Useful Review Unbelievably, inositol has been instrumental in treating polycystic ovaries, aiding hormonal balance, stabilising the cardiovascular system, and prompting ovulation. It helps to lower triglycerides and reduces the risk of cancer.
Jarrow Formulas, Vegan IP6, 120 Veggie Capsules	8.3	8.1
9 Myo-inositol affects prostate cancer cells Proteomic Analysis of Anticancer Effect of Myo-inositol in Human Prostate Cancer (DU-145) Cell Line. Islam MJ, Muntaha S, Masum MM, Nowshin S, Salam S, et al. Proteomic Analysis of Anticancer Effect of Myo-inositol in Human Prostate Cancer (DU-145) Cell Line. Asian Pac J Cancer Prev. 2024;25:4447. doi:10.31557/APJCP.2024.25.12.4447 We investigated the potential benefits of Myo-inositol, a naturally occurring sugar alcohol, on DU-145 prostate cancer cells. By treating these cancer cells with various doses of Myo-inositol, we determined its half-maximal inhibitory concentration (IC50) using a simple method that measures cell viability. Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth. Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment. Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC). 9 Significant cancer support Most Useful Review 48 people found this helpful IP6 is an incredible supplement, significantly reducing the formation of harmful AGEs that damage our organs and contribute to diabetes complications. Its ability to lower these substances by a remarkable 40% is impressive. I recommend taking it before meals for optimal effects. IP6 is also a powerful anti-cancer agent. For those with diabetes and insulin resistance, I've found it synergistic with other supplements and providing substantial overall protection and energy boost.
Green Tea Extract
NOW Foods, Thermo Green Tea, Extra Strength, 700 mg, 90 Veg Capsules	8	8.4
8 Green tea extract shows promise against liver cancer Camellia sinensis methanolic leaves extract: Phytochemical analysis and anticancer activity against human liver cancer cells. Hanna DH, Al-Atmani AK, AlRashidi AA, Shafee EE. Camellia sinensis methanolic leaves extract: Phytochemical analysis and anticancer activity against human liver cancer cells. PLoS One. 2024;19:e0309795. doi:10.1371/journal.pone.0309795 We examined the effects of green tea methanolic extract (GTME) on human liver cancer cells. The study revealed that GTME contains bioactive antioxidants and anticancer compounds that can significantly inhibit the growth of HepG2 cancer cells while sparing healthy cells. We observed that GTME promotes apoptosis—a process that leads to cell death—in cancer cells, alongside evidence of its ability to halt cell cycle progression. However, further research, especially using animal models, is necessary to substantiate these promising findings. 9 Prevents cancer effectively Most Useful Review 1 people found this helpful Green tea is exceptionally beneficial in scavenging free radicals within the body, and it is remarkably effective in preventing cancer.
NOW Foods, Green Tea Extract, 400 mg, 250 Veg Capsules	8.1	8.2
8 Green tea extract shows promise against liver cancer Camellia sinensis methanolic leaves extract: Phytochemical analysis and anticancer activity against human liver cancer cells. Hanna DH, Al-Atmani AK, AlRashidi AA, Shafee EE. Camellia sinensis methanolic leaves extract: Phytochemical analysis and anticancer activity against human liver cancer cells. PLoS One. 2024;19:e0309795. doi:10.1371/journal.pone.0309795 We examined the effects of green tea methanolic extract (GTME) on human liver cancer cells. The study revealed that GTME contains bioactive antioxidants and anticancer compounds that can significantly inhibit the growth of HepG2 cancer cells while sparing healthy cells. We observed that GTME promotes apoptosis—a process that leads to cell death—in cancer cells, alongside evidence of its ability to halt cell cycle progression. However, further research, especially using animal models, is necessary to substantiate these promising findings. 9 Stops cancer development Most Useful Review 3 people found this helpful My moles stopped itching after I began taking green tea extract for cardiovascular health. After a stroke, I noticed changes and started the extract. In weeks, the itching subsided; I later learned it’s a strong antioxidant preventing cancer and slowing ageing.
Pectin
NOW Foods, Apple Pectin, 700 mg, 120 Veg Capsules	8.3	8
8 Pectin shows varied cancer cell effects Can Enzymatic Modified Pectin in Mediterranean Fruits Be Therapeutic Against Stomach Cancer? Üstün S, Kizil HE, Dertli E. Can Enzymatic Modified Pectin in Mediterranean Fruits Be Therapeutic Against Stomach Cancer?. Food Sci Nutr. 2024;12:9469. doi:10.1002/fsn3.4507 We set out to determine if enzymatically modified pectin from grapefruit, jujube, and kumquat could be effective against stomach cancer cells. Through lab tests, we found that grapefruit pectin was particularly promising, displaying strong cytotoxic effects, especially at 0.075 mg/mL. Kumquat pectin also showed effectiveness across different concentrations. However, jujube pectin only exhibited cytotoxicity at lower concentrations. While the results indicate some potential, further research is needed to fully understand pectin's role in cancer treatment. 9 Prevents colon cancer Most Useful Review 1 people found this helpful I took pectin to eliminate heavy metals and normalise digestion, and it successfully performed both tasks, acting as a sponge to cleanse our bodies. It captures toxins and waste products, ensuring harmful substances do not linger in the intestines, thus helping to prevent colon cancer. Pectin also provides a feeling of fullness, which is important for those aiming to lose weight, reduces putrefaction in the intestines, purges toxins, heals the intestinal mucosa, and enhances vitamin and mineral absorption from food, except iron.
L Taurine
NOW Foods, Double Strength Taurine, 1,000 mg, 250 Veg Capsules	7.9	8.4
8 Taurine's protective role in cancer Interplay of serum taurine, S-adenosylmethionine, and cysteine levels in cancer risk: a prospective study. Liu C, Liu T, Wei Y, Shi J, Deng L, et al. Interplay of serum taurine, S-adenosylmethionine, and cysteine levels in cancer risk: a prospective study. Front Pharmacol. 2024;15:1507125. doi:10.3389/fphar.2024.1507125 We conducted a nested case-control study within a large cohort to understand how levels of taurine, S-adenosylmethionine (SAM), and cysteine in our blood are related to cancer risk, particularly among Chinese adults. Our analysis included 1,391 cancer cases matched with 1,391 controls, providing a robust framework for our findings. Our results showed that higher levels of taurine in the blood could reduce overall cancer risk, particularly for digestive cancers. This is an exciting discovery as it suggests that taurine might play a protective role. On the contrary, elevated levels of SAM appeared linked to an increased risk of digestive cancers. Using advanced statistical models, we identified complex interactions among taurine, SAM, and cysteine. Notably, we observed a significant overall negative association between the combination of these amino acids and cancer risk, highlighting the intricate balance these compounds maintain in our metabolism. Overall, while taurine seems to confer some protective benefits, the specific metabolic relationships and their implications for treatment and prevention strategies need further exploration. Our findings could pave the way for new approaches in cancer prevention. 7.5 Effective for metastasis Most Useful Review 5 people found this helpful Very good! I know it is effective for cancer, and I use it to help my husband's peritoneal cancer metastasis. Additionally, I take it to improve my bad cholesterol. I believe it benefits both conditions. I would recommend it, but it can cause significant tiredness.
Jarrow Formulas, Taurine , 1,000 mg, 100 Capsules	7.9	7.8
8 Taurine's protective role in cancer Interplay of serum taurine, S-adenosylmethionine, and cysteine levels in cancer risk: a prospective study. Liu C, Liu T, Wei Y, Shi J, Deng L, et al. Interplay of serum taurine, S-adenosylmethionine, and cysteine levels in cancer risk: a prospective study. Front Pharmacol. 2024;15:1507125. doi:10.3389/fphar.2024.1507125 We conducted a nested case-control study within a large cohort to understand how levels of taurine, S-adenosylmethionine (SAM), and cysteine in our blood are related to cancer risk, particularly among Chinese adults. Our analysis included 1,391 cancer cases matched with 1,391 controls, providing a robust framework for our findings. Our results showed that higher levels of taurine in the blood could reduce overall cancer risk, particularly for digestive cancers. This is an exciting discovery as it suggests that taurine might play a protective role. On the contrary, elevated levels of SAM appeared linked to an increased risk of digestive cancers. Using advanced statistical models, we identified complex interactions among taurine, SAM, and cysteine. Notably, we observed a significant overall negative association between the combination of these amino acids and cancer risk, highlighting the intricate balance these compounds maintain in our metabolism. Overall, while taurine seems to confer some protective benefits, the specific metabolic relationships and their implications for treatment and prevention strategies need further exploration. Our findings could pave the way for new approaches in cancer prevention. 9 Cancer prevention Most Useful Review This product prevents the onset of cancer and reduces blood glucose levels. It assists in the formation and restoration of the retina within the eyes after injuries and helps to normalise blood pressure. The quality is exceptional, and the dosage is excellent.
Pumpkin Seeds Pepitas
NOW Foods, Real Food, Raw Pumpkin Seeds, Unsalted, 16 oz (454 g)	8.2	8.1
9 METTL14 modifications impact AML Specific sDMA modifications on the RGG/RG motif of METTL14 regulate its function in AML. Zhong Y, Zhang R, Lu L, Tan H, You Y, et al. Specific sDMA modifications on the RGG/RG motif of METTL14 regulate its function in AML. Cell Commun Signal. 2025;23:126. doi:10.1186/s12964-025-02130-1 We explored how specific changes to the METTL14 protein affect cancer, particularly in acute myeloid leukemia (AML). By examining the RG-rich region of METTL14, we discovered that a special form of arginine methylation called symmetric dimethylation, specifically at positions R425 and R445, plays a vital role in enhancing its function. Our research revealed that this modification not only improves the activity of the METTL3:METTL14 complex but also influences which genes get expressed in cancer cells. We found that the presence of symmetric dimethylarginines helps the complex deposit a crucial chemical mark, known as m6A, on RNA, which is essential for the regulation of gene activity. Furthermore, we conducted a series of experiments that indicated a potential therapeutic angle in targeting the METTL3 and PRMT5 proteins. When both are inhibited, we observed a significant drop in the expression of genes important for AML cell growth, hinting at new possibilities for treating this challenging cancer. Overall, this study highlights the intricate relationship between protein modifications and cancer biology, emphasizing the potential for more targeted approaches in therapy. 7.5 Supports cancer treatment Most Useful Review 5 people found this helpful I ordered pumpkin seeds for the first time and found them to be of excellent quality. They are small, clean, and loved by my children. I give them daily due to their beneficial composition, which includes high protein and healthy fats. Regular consumption is believed to help combat cancer, boost immunity, and improve overall health without side effects. Additionally, they may assist with various ailments and are rich in essential vitamins and minerals. I really enjoyed them and will definitely repurchase.
Probiotics
21st Century, Acidophilus Probiotic Blend, 150 Capsules	8.1	8.1
9 Probiotics show promise against colorectal cancer Analyzing of colorectal cancerrelated genes and microRNAs expression profiles in response to probiotics Lactobacillus acidophilus and Saccharomyces cerevisiae in colon cancer cell lines. Saffar KN, Larypoor M, Torbati MB. Analyzing of colorectal cancerrelated genes and microRNAs expression profiles in response to probiotics Lactobacillus acidophilus and Saccharomyces cerevisiae in colon cancer cell lines. Mol Biol Rep. 2024;51:122. doi:10.1007/s11033-023-09008-w This study focused on how Lactobacillus acidophilus and Saccharomyces cerevisiae might affect colorectal cancer cells. We discovered that these probiotics could effectively reduce the growth of cancer cells in two specific lines, HT29 and SW480. Notably, the probiotics influenced the expression of key genes related to cell death and cancer growth, showing an upregulation of tumor-suppressing genes and microRNAs, while downregulating oncogenes. This suggests they could play a significant role in fighting colorectal cancer and contributing to prevention. 7.5 Reduced tumor growth Most Useful Review 9 people found this helpful Excellent product. If used correctly, Lactobacillus acidophilus makes a great contribution to the human body, particularly on three fronts: increasing antimicrobial activity, strengthening the intestinal barrier, and stimulating the immune system. The immunological benefits are significant; L. acidophilus can modulate the immune response by enhancing lymphocyte proliferation. This leads to reduced tumour growth, the inhibition of bacterial cancer enzymes, and lower production of the cytokine that shields tumours from immune surveillance.
L Glutamine
Jarrow Formulas, L-Glutamine, 1,000 mg, 100 Tablets	8	8.2
9 Targeted treatment for colon cancer Evaluation of Anticancer Activity of Novel and Tumor-Targeted Glutamine-Conjugated Organotin(IV) Compounds in Colorectal Cancer─An In Vitro and In Vivo Study. Sharma S, Kaur V, Duhan P, Singh R, Agnihotri N. Evaluation of Anticancer Activity of Novel and Tumor-Targeted Glutamine-Conjugated Organotin(IV) Compounds in Colorectal Cancer─An In Vitro and In Vivo Study. J Med Chem. 2025;68:2593. doi:10.1021/acs.jmedchem.4c01728 We focused on the potential of l-glutamine-conjugated organotin(IV) compounds as a targeted treatment for colorectal cancer. These compounds were tested in laboratory settings against human colon cancer cell lines, revealing marked cytotoxic effects. Through our observations, we noted that these compounds were capable of inducing cell cycle arrest and promoting apoptosis, which are key processes in halting cancer cell growth. When applied in an experimental model of colon cancer, they effectively reduced tumor sizes and volume while selectively accumulating in the colon with minimal toxicity. Importantly, our findings suggest that these glutamine-linked compounds not only exhibit strong anti-tumor activity but also address the issue of systemic toxicity often seen with traditional therapies. Overall, we believe these compounds could potentially serve as promising candidates in the fight against colon cancer. 9 Increased energy Most Useful Review I bought it for my mum, a breast cancer survivor, and this supplement provides her with more energy. It’s a fantastic product.
Folic Acid
21st Century, Folic Acid, 400 mcg, 250 Easy to Swallow Tablets	8.5	7.7
9 Effective targeted drug delivery system Folic Acid-Targeted Liposome-Based Nanoparticle Loaded with Sorafenib for Liver Cancer Therapy. Liu S, Yi D, Ma R, Zhang W. Folic Acid-Targeted Liposome-Based Nanoparticle Loaded with Sorafenib for Liver Cancer Therapy. Int J Nanomedicine. 2025;20:3933. doi:10.2147/IJN.S489777 We developed a folic acid-targeted liposome system to improve the delivery of sorafenib, a drug used in treating liver cancer. Through various techniques, we created liposomes loaded with sorafenib and evaluated their effects on liver cancer cells. Our results showed that this targeted system effectively inhibited cancer cell growth and induced apoptosis in vitro. Additionally, in a liver xenograft model, it successfully slowed tumor progression. Overall, our findings suggest that this targeted delivery method could enhance liver cancer therapy while minimizing side effects. 9 Reduces stomach cancer Most Useful Review During times of stress, like war, one folic acid tablet significantly reduces the risk of stomach cancer from alcohol consumption.
Jarrow Formulas, Vegan Methyl Folate, Extra Strength, 400 mcg, 60 Veggie Capsules	8.5	7.3
9 Effective targeted drug delivery system Folic Acid-Targeted Liposome-Based Nanoparticle Loaded with Sorafenib for Liver Cancer Therapy. Liu S, Yi D, Ma R, Zhang W. Folic Acid-Targeted Liposome-Based Nanoparticle Loaded with Sorafenib for Liver Cancer Therapy. Int J Nanomedicine. 2025;20:3933. doi:10.2147/IJN.S489777 We developed a folic acid-targeted liposome system to improve the delivery of sorafenib, a drug used in treating liver cancer. Through various techniques, we created liposomes loaded with sorafenib and evaluated their effects on liver cancer cells. Our results showed that this targeted system effectively inhibited cancer cell growth and induced apoptosis in vitro. Additionally, in a liver xenograft model, it successfully slowed tumor progression. Overall, our findings suggest that this targeted delivery method could enhance liver cancer therapy while minimizing side effects. 9 Has anticancer properties Most Useful Review Methylfolate, the active form of folic acid, crosses the blood-brain barrier to promote a healthy nervous system. It supports cardiovascular health by managing homocysteine levels, which are linked to heart disease. Methylfolate aids in the production of essential neurotransmitters and improves mood. It positively affects cognitive functions and has been shown to have anticancer effects against various tumours, including cervical and colorectal cancers.
Ubiquinol Coq10
NOW Foods, Ubiquinol, 100 mg, 120 Softgels	8	8.2
8 Ubiquinol aids radiation gut health Gastroprotective and microbiome-modulating effects of ubiquinol in rats with radiation-induced enteropathy. Eraqi WA, El-Sabbagh WA, Aziz RK, Elshahed MS, Youssef NH, et al. Gastroprotective and microbiome-modulating effects of ubiquinol in rats with radiation-induced enteropathy. Anim Microbiome. 2024;6:40. doi:10.1186/s42523-024-00320-9 In a fascinating exploration of how ubiquinol may aid in managing cancer-related issues, we investigated its effects on radiation-induced enteropathy—a condition that can severely impact patients undergoing radiotherapy. Using a well-structured study design, we divided male albino rats into four groups: one that received only radiation, and three others that received varying treatments with ubiquinol either before or after exposure to radiation. Our findings revealed that the rats treated with ubiquinol showed marked improvements in gut health when compared to those that only experienced radiation. We saw indications of enhanced healing in their intestinal tissues, including the recovery of important cells and reduced inflammation markers. Notably, the gut microbiomes of the ubiquinol-treated groups began to resemble those of healthy control rats, indicating that this treatment may help restore balance to the gut flora disrupted by radiation. This research highlights the potential of ubiquinol not only to protect the gut from radiation damage but also to support overall health in cancer patients by aiding in the recovery of gut microbiota diversity. It seems that ubiquinol could indeed play a significant role in enhancing the quality of life for individuals undergoing cancer treatments, particularly those affected by gastrointestinal side effects. 7.5 Prevents disease progression Most Useful Review 8 people found this helpful Excellent ubiquinol. It is the reduced form of Coenzyme Q10, meaning it is absorbed more efficiently. This potent antioxidant is often lacking in our diets, especially after 30, leading to quicker skin aging and potentially diminishing organ and cognitive function. Ubiquinol is crucial for countering free radicals, which can cause cellular dysfunction and elevate cancer risk. Sufficient intake can avert various diseases, from cancer to Alzheimer's. Ubiquinol has also proven effective in treating COVID-19 and its aftermath. I highly recommend it for regular use and therapeutic purposes!
Efa Omega 3 6 9 Combinations
NOW Foods, Wheat Germ Oil, 16 fl oz (473 ml)	8	8.2
8 Gamma-tocopherol in cancer research Gamma-Tocopherol: A Comprehensive Review of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties. Es-Sai B, Wahnou H, Benayad S, Rabbaa S, Laaziouez Y, et al. Gamma-Tocopherol: A Comprehensive Review of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties. Molecules. 2025;30. doi:10.3390/molecules30030653 We examined the effects of gamma-tocopherol, a major form of vitamin E, on cancer treatment and prevention. This powerful antioxidant is noted for its ability to combat oxidative stress, which plays a significant role in the development and progression of various cancers. In several studies, we observed that gamma-tocopherol not only neutralizes harmful reactive oxygen species but also exhibits anti-inflammatory properties. These characteristics help reduce chronic inflammation tied to cancer risks. Furthermore, it has shown the potential to inhibit tumor growth, induce cancer cell death, and restrict blood vessel formation that tumors require to grow. Specifically, findings indicated that gamma-tocopherol is particularly effective in cancers such as prostate, lung, and colon. With promising results from both preclinical and clinical trials, there is a growing interest in how this natural compound can be beneficial in cancer management. While we noted excellent tolerance at normal doses, it’s essential to consider careful monitoring at higher levels to avoid any adverse effects. Hence, we believe that ongoing research and advancements in drug delivery methods could further enhance its effectiveness. 7.5 Skin cancer prevention Most Useful Review 34 people found this helpful The yellow colour of the oil may appear darker than others. Its texture is rather heavy, and while the quality is satisfactory, the smell resembles oatmeal and lingers. Despite this, its benefits outweigh the drawbacks, as it accelerates healing for skin wounds and burns, reduces scar appearance, alleviates itching, and helps prevent skin cancer. Additionally, it can lighten skin tone and address hair breakage and stretch marks. Being a larger package, it's advisable to use it in mixtures for hair or skin, as it should be diluted for effective use. If my comment helps, please give a like 💗
Lactobacillus
Jarrow Formulas, Jarro-Dophilus EPS, 10 Billion CFU, 60 Veggie Capsules	8	8.1
8 Bifidobacterium longum shows potential benefits Bifidobacterium longum subsp. longum XZ01 delays the progression of colon cancer in mice through the interaction between the microbial spatial distribution and tumour immunity. Chen Y, Wu J, Cai K, Xiao X, Chen Y, et al. Bifidobacterium longum subsp. longum XZ01 delays the progression of colon cancer in mice through the interaction between the microbial spatial distribution and tumour immunity. Int Immunopharmacol. 2025;150:114283. doi:10.1016/j.intimp.2025.114283 We investigated whether Bifidobacterium longum XZ01 could affect the progression of colon cancer in a mouse model. The results hinted that this probiotic might enhance immune responses by outcompeting harmful bacteria and protecting macrophages within tumors. Notably, XZ01 appears to foster a favorable tumor immune environment, promoting immune cell activation while inhibiting certain immune suppression. By interacting with microbial communities, this treatment shows promise for potentially improving colon cancer immunotherapy strategies. More research is necessary to confirm these effects in humans, but these findings open doors to innovative cancer treatments. 7.5 Improved intestinal health Most Useful Review 1 people found this helpful I am pleasantly surprised. After taking 2 or 3 tablets daily for ten days, I noticed positive changes. My usual morning stool now comes out around 2 pm. Previously, I experienced painful bloating after lunch, but that discomfort has disappeared, and my bowel movements are much smoother. After my mother died of colon cancer, I feared inheriting that issue, so I started this to improve my gut health. I look forward to continuing this and hope it will benefit both my intestinal and skin health over the next three months.
Ashwagandha
Himalaya, Organic Ashwagandha, 60 Caplets	7.9	8.2
9 DHA affects colorectal cancer pathways Dietary polyunsaturated fatty acids affect PPARγ promoter methylation status and regulate the PPARγ/COX2 pathway in some colorectal cancer cell lines. Babaeenezhad E, Khosravi P, Moradi Sarabi M. Dietary polyunsaturated fatty acids affect PPARγ promoter methylation status and regulate the PPARγ/COX2 pathway in some colorectal cancer cell lines. Genes Nutr. 2025;20:2. doi:10.1186/s12263-025-00764-x We set out to explore how docosahexaenoic acid (DHA), a type of omega-3 fatty acid, affects colorectal cancer (CRC) cells. In this study, we treated five different colorectal cancer cell lines with varying concentrations of DHA, along with other fatty acids like eicosapentaenoic acid (EPA) and linoleic acid (LA). This allowed us to see if DHA could impact the methylation patterns of the PPARγ promoter, a key player in cancer regulation, and affect the relationship between PPARγ and COX2, two important molecules involved in cancer growth. Our findings revealed that DHA significantly altered the methylation status in some cell lines, effectively demethylating specific regions of the PPARγ promoter. We observed that this demethylation was linked to an increase in the expression of PPARγ in cells where it was hemimethylated. Interestingly, DHA not only boosted PPARγ levels but also downregulated COX2 across all CRC cell lines tested. This suggests that DHA might have a role in reducing inflammatory signals linked to cancer progression. The overall impact seemed to vary depending on the type of cancer cell we were working with, indicating a cell type-dependent effect of DHA. Notably, we found that DHA was more effective than EPA or LA in modulating the PPARγ promoter. This research shows promising potential for DHA in colorectal cancer treatment and highlights its importance in dietary considerations for cancer management. 9 Aid during treatment Most Useful Review This brand helped significantly during my battle with cancer. After years of consistent use, I believe the quality remains high. The caplets may have a strong odour, but with water, I manage to take them without any issues.
Calcium Magnesium
NOW Foods, Calcium & Magnesium, 250 Tablets	7.8	8.3
8 Magnesium alloy inhibits cancer growth Biodegradable Mg-1%Ca alloy inhibits the growth of cervical cancer. Ouyang Y, Cao L, Zhao Q, Yang W, Lin C. Biodegradable Mg-1%Ca alloy inhibits the growth of cervical cancer. Biomed Mater. 2025. doi:10.1088/1748-605X/adb2cc We explored how magnesium alloy, particularly a variant containing 1% calcium, impacts cervical cancer cells. Our investigation revealed that this alloy has promising antitumor properties which could pave the way for new treatments. In our experiments, we tested the effects of the Mg-1%Ca alloy both in laboratory settings and in living organisms. This alloy was found to release magnesium ions and hydroxide ions more slowly than expected. We observed that it effectively inhibited the growth of cervical cancer cells, specifically SiHa and HeLa cell lines. Additionally, the presence of the alloy induced apoptosis, or programmed cell death, in the cancer cells, disrupted their structural integrity, and hindered their ability to migrate and invade other tissues. Importantly, the Mg-1%Ca alloy was seen to influence key molecular pathways, specifically the MAPK/ERK signaling pathway, which plays a role in cancer cell proliferation. With these results, it's evident that magnesium alloy could serve as a useful adjunct to current cervical cancer therapies, potentially helping to prevent both cancer growth and metastasis. 7.5 Normal health indicators Most Useful Review 1 people found this helpful For a friend, 60+ After cancer, a woman constantly takes some medications, the side effect of which is a decrease in bone density. The doctor recommended taking calcium in addition, along with magnesium and vitamin D3+K2 for better absorption. On control examinations, all her indicators are normal, as well as her well-being. ❤️
Vitamin E
NOW Foods, E-400, 268 mg (400 IU), 250 Softgels	7.8	8.3
8 Gamma-tocopherol in cancer research Gamma-Tocopherol: A Comprehensive Review of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties. Es-Sai B, Wahnou H, Benayad S, Rabbaa S, Laaziouez Y, et al. Gamma-Tocopherol: A Comprehensive Review of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties. Molecules. 2025;30. doi:10.3390/molecules30030653 We examined the effects of gamma-tocopherol, a major form of vitamin E, on cancer treatment and prevention. This powerful antioxidant is noted for its ability to combat oxidative stress, which plays a significant role in the development and progression of various cancers. In several studies, we observed that gamma-tocopherol not only neutralizes harmful reactive oxygen species but also exhibits anti-inflammatory properties. These characteristics help reduce chronic inflammation tied to cancer risks. Furthermore, it has shown the potential to inhibit tumor growth, induce cancer cell death, and restrict blood vessel formation that tumors require to grow. Specifically, findings indicated that gamma-tocopherol is particularly effective in cancers such as prostate, lung, and colon. With promising results from both preclinical and clinical trials, there is a growing interest in how this natural compound can be beneficial in cancer management. While we noted excellent tolerance at normal doses, it’s essential to consider careful monitoring at higher levels to avoid any adverse effects. Hence, we believe that ongoing research and advancements in drug delivery methods could further enhance its effectiveness. 9 Supports cancer prevention Most Useful Review 1 people found this helpful Vitamin E is a fat-soluble vitamin known for its antioxidant and radioprotective properties. It aids in the synthesis of heme and proteins, cell proliferation, and cellular metabolism. It enhances tissue oxygen consumption, supports heart function, and contributes to red blood cell formation. Vitamin E boosts the immune system, combats oxidative stress, and plays a preventive role against cancer. Overall, it is of good quality, well-packaged, and contributes to a calm nervous system as well as fast metabolism.
NOW Foods, Gamma E Complex, Advanced, 300 mg, 120 Softgels (150 mg per Softgel)	7.8	8.2
8 Gamma-tocopherol in cancer research Gamma-Tocopherol: A Comprehensive Review of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties. Es-Sai B, Wahnou H, Benayad S, Rabbaa S, Laaziouez Y, et al. Gamma-Tocopherol: A Comprehensive Review of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties. Molecules. 2025;30. doi:10.3390/molecules30030653 We examined the effects of gamma-tocopherol, a major form of vitamin E, on cancer treatment and prevention. This powerful antioxidant is noted for its ability to combat oxidative stress, which plays a significant role in the development and progression of various cancers. In several studies, we observed that gamma-tocopherol not only neutralizes harmful reactive oxygen species but also exhibits anti-inflammatory properties. These characteristics help reduce chronic inflammation tied to cancer risks. Furthermore, it has shown the potential to inhibit tumor growth, induce cancer cell death, and restrict blood vessel formation that tumors require to grow. Specifically, findings indicated that gamma-tocopherol is particularly effective in cancers such as prostate, lung, and colon. With promising results from both preclinical and clinical trials, there is a growing interest in how this natural compound can be beneficial in cancer management. While we noted excellent tolerance at normal doses, it’s essential to consider careful monitoring at higher levels to avoid any adverse effects. Hence, we believe that ongoing research and advancements in drug delivery methods could further enhance its effectiveness. 9 Prevents cancer development Most Useful Review 5 people found this helpful Tocotrienols enhance the cardiovascular system and brain activity; they prevent cancer cell development and trigger their self-destruction. Their potent antioxidant action safeguards nerve cells from disease, offers a remarkable rejuvenating effect, and wards off diabetes.
NOW Foods, E-400 with Mixed Tocopherols, 268 mg (400 IU), 100 Softgels	7.8	8.1
8 Gamma-tocopherol in cancer research Gamma-Tocopherol: A Comprehensive Review of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties. Es-Sai B, Wahnou H, Benayad S, Rabbaa S, Laaziouez Y, et al. Gamma-Tocopherol: A Comprehensive Review of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties. Molecules. 2025;30. doi:10.3390/molecules30030653 We examined the effects of gamma-tocopherol, a major form of vitamin E, on cancer treatment and prevention. This powerful antioxidant is noted for its ability to combat oxidative stress, which plays a significant role in the development and progression of various cancers. In several studies, we observed that gamma-tocopherol not only neutralizes harmful reactive oxygen species but also exhibits anti-inflammatory properties. These characteristics help reduce chronic inflammation tied to cancer risks. Furthermore, it has shown the potential to inhibit tumor growth, induce cancer cell death, and restrict blood vessel formation that tumors require to grow. Specifically, findings indicated that gamma-tocopherol is particularly effective in cancers such as prostate, lung, and colon. With promising results from both preclinical and clinical trials, there is a growing interest in how this natural compound can be beneficial in cancer management. While we noted excellent tolerance at normal doses, it’s essential to consider careful monitoring at higher levels to avoid any adverse effects. Hence, we believe that ongoing research and advancements in drug delivery methods could further enhance its effectiveness. 8 Synergistic effects Most Useful Review 89 people found this helpful Vitamin E is vital for those practising Fujikawa's theory. High in antioxidants, it is expected to offer anti-aging benefits and cancer prevention. It enhances the effects of vitamins B and C when taken separately.
Herbal Extracts
Nature's Way, Echinacea Purpurea Herb, 1,200 mg, 180 Vegan Capsules (400 mg per Capsule)	7.8	8.2
9 Echinacea modulates gut health in cancer Echinacea purpurea polysaccharide intervene in hepatocellular carcinoma via modulation of gut microbiota to inhibit TLR4/NF-κB pathway. Jing G, Xu W, Ma W, Yu Q, Zhu H, et al. Echinacea purpurea polysaccharide intervene in hepatocellular carcinoma via modulation of gut microbiota to inhibit TLR4/NF-κB pathway. Int J Biol Macromol. 2024;261:129917. doi:10.1016/j.ijbiomac.2024.129917 We investigated how Echinacea purpurea polysaccharide (EPP) might help in fighting hepatocellular carcinoma, a common type of liver cancer. Our findings showed that EPP not only reduced liver damage caused by cancer but also helped in slowing down cancer cell growth and promoting their death, a process known as apoptosis. An interesting aspect of our study was how EPP influenced gut microbiota. After treatment with EPP, we observed a significant increase in beneficial bacteria that produce propionic and butyric acids. These changes in gut microbes led to strengthening the intestinal barrier, which is crucial for keeping harmful substances like lipopolysaccharides (LPS) from leaking into the bloodstream. By controlling LPS leakage, EPP helped reduce inflammation and hindered the TLR4/NF-κB signaling pathway that cancer cells often exploit to survive. On a molecular level, our metabolomics analysis revealed that EPP treatment downregulated certain metabolic pathways associated with tumor growth while enhancing butyrate metabolism, which is linked to healthier cellular functions. Overall, our research highlights EPP's potential to combat liver cancer through beneficial modifications to the gut microbiome and consequent impacts on inflammation and cancer cell survival. 7.5 Effective immunity boost Most Useful Review 3 people found this helpful Excellent! The echinacea plant is well-known for enhancing immunity and combating cancer cells. It's particularly useful for those with immunodeficiency. I obtained it for my mother and noticed an improvement in her condition. I highly recommend this brand as its products are very effective and the results are remarkable.
Gaia Herbs, Olive Leaf, 680 mg, 60 Vegan Liquid Phyto-Caps	N/A	8.3
7.5 Promising against cancer Most Useful Review 4 people found this helpful A very useful drug! The oleuropein in olive oil contributes to its medicinal properties. Olive leaves have high oleuropein content, making the extract a valuable nutrient source. Research into olive leaf extracts shows promise in preventing diseases, including hypertension, heart disease, diabetes, and cancer. 7.5 Supports cancer defense Most Useful Review 2 people found this helpful We use this for the whole family to boost immunity. Olive leaves possess various beneficial properties, improving cardiovascular health and fighting diabetes and cancer, while enhancing immune defences. The natural composition lends the company my trust.
NOW Foods, Olive Leaf Extract, 500 mg, 120 Veg Capsules	N/A	8
9 Strong antimicrobial activity Most Useful Review Olive leaf extract is a staple in my medicine cabinet. I have tested various brands and value standardized oleuropein content. This specific product contains 18% oleuropein, which is acceptable, although I typically prefer 20%. I take it to prevent viral infections in aggressive environments. This extract's antimicrobial, antiviral, and anti-inflammatory effects are impressive. Moreover, it supports heart health and has notable anti-cancer properties. It is well tolerated, but hypotensive patients should use it cautiously. 9 Improves immunity Most Useful Review 11 people found this helpful Olive leaves are rich in oleuropein, making the extract a vital nutrient source. Research on olive leaf extracts indicates strong potential in preventing conditions such as hypertension, heart disease, diabetes, cancer, stroke, Alzheimer's, and arthritis. It significantly reduces high blood pressure and bolsters the immune system. I use it for tumour prevention and find it effective at the onset of flu, eliminating the need for costly antiviral medicines. I highly recommend this product.
Ip6
Nature's Way, Cell Forté MAX3, 120 Vegan Capsules	7.9	8.1
9 IP6 shows promise against prostate cancer Stage-Specific Effect of Inositol Hexaphosphate on Cancer Stem Cell Pool during Growth and Progression of Prostate Tumorigenesis in TRAMP Model. Raina K, Kandhari K, Jain AK, Ravichandran K, Maroni P, et al. Stage-Specific Effect of Inositol Hexaphosphate on Cancer Stem Cell Pool during Growth and Progression of Prostate Tumorigenesis in TRAMP Model. Cancers (Basel). 2022;14. doi:10.3390/cancers14174204 We explored how inositol hexaphosphate (IP6), a natural compound, influences prostate cancer growth and development in a mouse model. Male TRAMP mice were given either regular water or a solution with 2% IP6 for 8-15 weeks, starting at different ages. Remarkably, IP6 treatment halted tumor growth at earlier stages and significantly reduced the incidence of aggressive cancer types by 55-70%. Additionally, IP6 appears to target cancer stem cells, which play a role in tumor persistence and progression. In lab tests, IP6 reduced self-renewal in cancer stem cell clusters by about 90%. Overall, our findings highlight IP6's potential as a powerful tool in early-stage prostate cancer prevention. 7.5 Effective for animals Most Useful Review 17 people found this helpful Cell Forte Max3 has worked wonders for animals with cancer. I’ve seen it help my hedgehog with liver cancer and a friend’s horse with skin cancer. It also aided my dog with autoimmune issues. After one month, a fatty tumour I had shrank by half. This product is exceedingly safe, and I’ve been a fan since 1990.
Calcium
Nature's Bounty, Calcium Magnesium Zinc with Vitamin D3, 100 Coated Caplets	7.8	8.2
8 Magnesium alloy inhibits cancer growth Biodegradable Mg-1%Ca alloy inhibits the growth of cervical cancer. Ouyang Y, Cao L, Zhao Q, Yang W, Lin C. Biodegradable Mg-1%Ca alloy inhibits the growth of cervical cancer. Biomed Mater. 2025. doi:10.1088/1748-605X/adb2cc We explored how magnesium alloy, particularly a variant containing 1% calcium, impacts cervical cancer cells. Our investigation revealed that this alloy has promising antitumor properties which could pave the way for new treatments. In our experiments, we tested the effects of the Mg-1%Ca alloy both in laboratory settings and in living organisms. This alloy was found to release magnesium ions and hydroxide ions more slowly than expected. We observed that it effectively inhibited the growth of cervical cancer cells, specifically SiHa and HeLa cell lines. Additionally, the presence of the alloy induced apoptosis, or programmed cell death, in the cancer cells, disrupted their structural integrity, and hindered their ability to migrate and invade other tissues. Importantly, the Mg-1%Ca alloy was seen to influence key molecular pathways, specifically the MAPK/ERK signaling pathway, which plays a role in cancer cell proliferation. With these results, it's evident that magnesium alloy could serve as a useful adjunct to current cervical cancer therapies, potentially helping to prevent both cancer growth and metastasis. 7.5 Cancer prevention support Most Useful Review 68 people found this helpful Calcium and magnesium, along with zinc, are essential for immune support, bones, and overall health. These elements are vital for bone, teeth, and muscle tone health. Zinc bolsters immune functions, aids in healing, and is crucial for the prostate and reproductive systems. The combination with Vitamin D3 enhances calcium absorption. However, I find taking these tablets three times daily rather inconvenient. The blend plays an essential role in cancer prevention.
Rutin
NOW Foods, Rutin, 450 mg, 100 Veg Capsules	8	8
9 Leaf extract shows anticancer promise Bioactivity Evaluation and Phytochemical Characterization of (Thunb.) Siebold Leaf Extract. Yoon WJ, Min HJ, Cho HD, Kim HG, Park WL, et al. Bioactivity Evaluation and Phytochemical Characterization of (Thunb.) Siebold Leaf Extract. Biomedicines. 2024;12. doi:10.3390/biomedicines12122928 We examined the various health benefits of leaf extract, particularly its potential against cancer. The research revealed that the ethanol extract is rich in beneficial compounds like rutin and demonstrated significant antioxidant activities. Notably, it selectively inhibited the growth of specific cancer cells while sparing normal cells. Additionally, treatment led to improved survival in tumor-bearing mice, showcasing its possible life-prolonging properties. Overall, our findings suggest that this leaf extract could be a promising natural source for antioxidant and anticancer support. 9 Reduces cancer risk Most Useful Review The element reduces the risk of developing cancer cells, particularly effective against blood and breast cancer. It also alleviates eye pressure. Rutin is a powerful ingredient that guarantees a reduction in intraocular pressure to a safe level.
Prebiotic Fiber Inulin
NOW Foods, Certified Organic Inulin, Prebiotic Pure Powder, 8 oz (227 g)	7.7	8.2
8 Inulin's effects on colonic fibrosis Exploring the Role of Inulin in Targeting the Gut Microbiota: An Innovative Strategy for Alleviating Colonic Fibrosis Induced By Irradiation. Ji K, Zhang M, Du L, Wang J, Liu Y, et al. Exploring the Role of Inulin in Targeting the Gut Microbiota: An Innovative Strategy for Alleviating Colonic Fibrosis Induced By Irradiation. J Agric Food Chem. 2024;72:5710. doi:10.1021/acs.jafc.3c03432 We explored the effects of inulin supplements on colonic fibrosis caused by radiation therapy for treating pelvic and abdominal cancers. Chronic radiation enteropathy often leads to difficult gastrointestinal issues, and understanding how inulin can help is crucial. In our study, we found that inulin seems to promote the growth of beneficial bacteria in the gut, which in turn boosts the production of short-chain fatty acids (SCFAs). By conducting experiments on mice with chronic radiation enteropathy, we discovered that when we transplanted gut microbiota and their metabolites from inulin-treated mice, the levels of colonic fibrosis significantly decreased. Additionally, administering these metabolites led to a drop in the expression of genes related to fibrosis and collagen production in mouse embryonic fibroblast cells. It appears that these inulin-derived metabolites also inhibit the pathways involved in the production of the extracellular matrix. Overall, our findings highlight the promise of inulin as a novel approach to help mitigate chronic radiation-induced colonic fibrosis. 7.5 Boosts immune system Most Useful Review 6 people found this helpful I chose Inulin over other prebiotics after consulting with my gastroenterologist. It reaches the bowels where beneficial bacteria grow and inhibits certain fats' growth. Inulin serves as a valuable dietary fibre and helps reduce the risk of cancer while enhancing immune functions. If this review has helped you, please give it a thumbs up. Thank you!
L Glutathione
NOW Foods, Glutathione, 500 mg, 60 Veg Capsules	7.8	8.1
9 Investigating silibinin's cancer treatment role Anti-Tumor Activity and Mechanism of Silibinin Based on Network Pharmacology and Experimental Verification. Li P, Wang D, Yang X, Liu C, Li X, et al. Anti-Tumor Activity and Mechanism of Silibinin Based on Network Pharmacology and Experimental Verification. Molecules. 2024;29. doi:10.3390/molecules29081901 We aimed to uncover how silibinin, a compound from milk thistle, impacts cancer, specifically in adenoid cystic carcinoma cells and Balb/c nude mice. The study identified 75 key targets linked to tumor growth and showcased that silibinin significantly reduced cell viability, proliferation, and migration. Additionally, it induced cancer cell death and inhibited tumor growth in live subjects. Our findings highlighted how silibinin acts on specific proteins affecting cancer pathways, offering valuable insights into its potential as an anti-tumor treatment. 9 Aid after chemotherapy Most Useful Review This powerful antioxidant is found naturally in fruits and vegetables and produced by the body. As a cancer patient, I use this product following my chemotherapy and radiation treatments to facilitate quicker recovery and detox.
Lecithin
NOW Foods, Sunflower Lecithin, 1,200 mg, 200 Softgels	8.1	7.8
9 Lecithin enhances lung cancer radiation Soybean Lecithin-Gallic Acid Complex Sensitizes Lung Cancer Cells to Radiation Through Ferroptosis Regulated by Nrf2/SLC7A11/GPX4 Pathway. Chen X, Cui H, Qin L, Liu R, Fang F, et al. Soybean Lecithin-Gallic Acid Complex Sensitizes Lung Cancer Cells to Radiation Through Ferroptosis Regulated by Nrf2/SLC7A11/GPX4 Pathway. Nutrients. 2025;17. doi:10.3390/nu17071262 We examined how a soybean lecithin-gallic acid complex (SL-GAC) could help overcome the challenges in lung cancer radiotherapy. Our findings show that when combined with radiation, SL-GAC significantly reduced the proliferation and migration of lung cancer cells while inducing oxidative stress and ferroptosis. This treatment also led to changes in critical cellular pathways. However, it did not significantly affect normal cells, indicating a potential targeted approach. Overall, while promising, further clinical exploration is needed to confirm these benefits. 9 Effectively treats conditions Most Useful Review Multiple studies show that combining lecithin with methionine and inositol aids in treating various diseases of the female reproductive system, including breast and uterine cancer. Lecithin effectively converts estradiol, which can provoke cancer, into a safer estriol. Additionally, it supports liver health and alleviates digestive disorders.
Vitamin D
21st Century, Vitamin D3, 50 mcg (2,000 IU), 250 Softgels	7.5	8.4
8 Vitamin D3 offers anti-cancer benefits Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Ezcurra-Hualde M, Zalba S, Bella Á, Arrizabalaga L, Risson A, et al. Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Front Immunol. 2025;16:1529007. doi:10.3389/fimmu.2025.1529007 We investigated the potential of vitamin D3, also known as cholecalciferol, in combating cancer while addressing concerns about its toxicity at higher doses. This study focused on enhancing the effectiveness of vitamin D3 through a clever method called liposomal encapsulation, which helps minimize side effects. We prepared liposomal vitamin D3 (VD-LP) and conducted various tests to understand its capabilities. We found that this encapsulated form not only maintained high efficiency but also demonstrated improved stability. Our analyses showed that VD-LP had strong effects against cancer cells from colorectal, breast, and prostate cancers. Remarkably, it affected gene expression in immune cells, boosting elements that help fight infections and support the body's defenses. Notably, VD-LP did a great job slowing tumor growth in mice and improved their survival rates without causing adverse effects like hypercalcemia, which is often a concern with regular vitamin D3 use. This evidence indicates that liposomal encapsulation of vitamin D3 could offer an effective cancer treatment strategy while minimizing unwanted side effects. We believe this may pave the way for further research and clinical applications, showcasing vitamin D3 as a valuable addition to cancer therapy. 9 Prevents rickets Most Useful Review Perfectly! During the covid exacerbation period, my homeopathic doctor recommended daily vitamin D3 to enhance immunity. I ordered this brand upon his advice, and the prevention results are excellent. Besides this, vitamin D3 supports bone growth, prevents rickets and osteoporosis, aids thyroid function, blood clotting, blood pressure regulation, and heart rate, and inhibits cancer cell growth. It's particularly beneficial for mood swings and depression in older adults. The UK Department of Health recommends adults in northern countries take vitamin D3 from October to March.
Solgar, Vitamin D 3 (Cholecalciferol), 25 mcg (1,000 IU), 100 Softgels	7.5	8.2
8 Vitamin D3 offers anti-cancer benefits Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Ezcurra-Hualde M, Zalba S, Bella Á, Arrizabalaga L, Risson A, et al. Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Front Immunol. 2025;16:1529007. doi:10.3389/fimmu.2025.1529007 We investigated the potential of vitamin D3, also known as cholecalciferol, in combating cancer while addressing concerns about its toxicity at higher doses. This study focused on enhancing the effectiveness of vitamin D3 through a clever method called liposomal encapsulation, which helps minimize side effects. We prepared liposomal vitamin D3 (VD-LP) and conducted various tests to understand its capabilities. We found that this encapsulated form not only maintained high efficiency but also demonstrated improved stability. Our analyses showed that VD-LP had strong effects against cancer cells from colorectal, breast, and prostate cancers. Remarkably, it affected gene expression in immune cells, boosting elements that help fight infections and support the body's defenses. Notably, VD-LP did a great job slowing tumor growth in mice and improved their survival rates without causing adverse effects like hypercalcemia, which is often a concern with regular vitamin D3 use. This evidence indicates that liposomal encapsulation of vitamin D3 could offer an effective cancer treatment strategy while minimizing unwanted side effects. We believe this may pave the way for further research and clinical applications, showcasing vitamin D3 as a valuable addition to cancer therapy. 9 Stronger immunity Most Useful Review 1 people found this helpful Vitamin D3 is essential for immunity and bone health, particularly during pandemics. A three-month course improved my energy and mood after I discovered my low levels. This reliable product from Solgar enhances calcium absorption, vascular health, and reduces the risk of cancer. I wholeheartedly recommend it to everyone.
Nature's Way, Vitamin D3, Extra Strength, 50 mcg (2,000 IU), 120 Softgels	7.5	8.2
8 Vitamin D3 offers anti-cancer benefits Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Ezcurra-Hualde M, Zalba S, Bella Á, Arrizabalaga L, Risson A, et al. Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Front Immunol. 2025;16:1529007. doi:10.3389/fimmu.2025.1529007 We investigated the potential of vitamin D3, also known as cholecalciferol, in combating cancer while addressing concerns about its toxicity at higher doses. This study focused on enhancing the effectiveness of vitamin D3 through a clever method called liposomal encapsulation, which helps minimize side effects. We prepared liposomal vitamin D3 (VD-LP) and conducted various tests to understand its capabilities. We found that this encapsulated form not only maintained high efficiency but also demonstrated improved stability. Our analyses showed that VD-LP had strong effects against cancer cells from colorectal, breast, and prostate cancers. Remarkably, it affected gene expression in immune cells, boosting elements that help fight infections and support the body's defenses. Notably, VD-LP did a great job slowing tumor growth in mice and improved their survival rates without causing adverse effects like hypercalcemia, which is often a concern with regular vitamin D3 use. This evidence indicates that liposomal encapsulation of vitamin D3 could offer an effective cancer treatment strategy while minimizing unwanted side effects. We believe this may pave the way for further research and clinical applications, showcasing vitamin D3 as a valuable addition to cancer therapy. 7.5 Convenient for patients Most Useful Review Take one of these; it provides 2000 IU, which is very convenient and suitable for cancer patients.
Solgar, Vitamin D3 (Cholecalciferol), 125 mcg (5,000 IU), 240 Vegetable Capsules	7.5	8.2
8 Vitamin D3 offers anti-cancer benefits Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Ezcurra-Hualde M, Zalba S, Bella Á, Arrizabalaga L, Risson A, et al. Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Front Immunol. 2025;16:1529007. doi:10.3389/fimmu.2025.1529007 We investigated the potential of vitamin D3, also known as cholecalciferol, in combating cancer while addressing concerns about its toxicity at higher doses. This study focused on enhancing the effectiveness of vitamin D3 through a clever method called liposomal encapsulation, which helps minimize side effects. We prepared liposomal vitamin D3 (VD-LP) and conducted various tests to understand its capabilities. We found that this encapsulated form not only maintained high efficiency but also demonstrated improved stability. Our analyses showed that VD-LP had strong effects against cancer cells from colorectal, breast, and prostate cancers. Remarkably, it affected gene expression in immune cells, boosting elements that help fight infections and support the body's defenses. Notably, VD-LP did a great job slowing tumor growth in mice and improved their survival rates without causing adverse effects like hypercalcemia, which is often a concern with regular vitamin D3 use. This evidence indicates that liposomal encapsulation of vitamin D3 could offer an effective cancer treatment strategy while minimizing unwanted side effects. We believe this may pave the way for further research and clinical applications, showcasing vitamin D3 as a valuable addition to cancer therapy. 9 Daily D3 intake Most Useful Review I have used Solgar vitamin D3 for several years, mainly because I avoid sun exposure due to skin cancer. I take it every day, and it's a very good product!
Nature's Bounty, D3, 50 mcg (2,000 IU), 350 Rapid Release Softgels	7.3	8.4
5 Vitamin D's role in breast disease Levels of Serum 25-Hydroxy Vitamin D in Benign and Malignant Breast Disease Patients: An Observational Study. Soni D, Tiwari A, Kushwah PS, Dubey S, Khan S. Levels of Serum 25-Hydroxy Vitamin D in Benign and Malignant Breast Disease Patients: An Observational Study. Cureus. 2025;17:e78283. doi:10.7759/cureus.78283 We conducted an observational study to examine the levels of vitamin D in female patients with benign and malignant breast diseases. The research aimed to determine if there is a significant difference in vitamin D levels between those with non-cancerous conditions and those diagnosed with breast cancer. During the study, we analyzed adult female patients admitted to a surgical department. Importantly, we excluded those who had taken vitamin D supplements recently or who had prior vitamin D deficiencies. By measuring serum vitamin D levels through a specific testing method, we were able to gather meaningful data about their relationship to breast health. Our findings indicated a notable difference in average vitamin D levels when comparing the two groups. This suggests that inadequate vitamin D could be linked to an increased risk of developing breast cancer. Therefore, we explored the potential benefits of vitamin D supplementation as a preventive measure against breast cancer—though we acknowledge that larger and more controlled studies are essential to draw firm conclusions. At the same time, we recognize that vitamin D has effects beyond bone health, and it is crucial to consider these broader impacts when discussing its role in cancer risk. 9 Resists cancer growth Most Useful Review I have repeatedly ordered this manufacturer's D3! This vitamin aids in muscle tone, enhances immunity, and is essential for thyroid function and blood clotting. It helps restore nerve protective membranes and plays a role in regulating blood pressure and heart rate, while resisting cancer cell growth. The quality is excellent, and I highly recommend this product!
NOW Foods, Vitamin D-3, Max Potency, 50,000 IU, 50 Softgels	7.5	8.1
8 Vitamin D3 offers anti-cancer benefits Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Ezcurra-Hualde M, Zalba S, Bella Á, Arrizabalaga L, Risson A, et al. Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Front Immunol. 2025;16:1529007. doi:10.3389/fimmu.2025.1529007 We investigated the potential of vitamin D3, also known as cholecalciferol, in combating cancer while addressing concerns about its toxicity at higher doses. This study focused on enhancing the effectiveness of vitamin D3 through a clever method called liposomal encapsulation, which helps minimize side effects. We prepared liposomal vitamin D3 (VD-LP) and conducted various tests to understand its capabilities. We found that this encapsulated form not only maintained high efficiency but also demonstrated improved stability. Our analyses showed that VD-LP had strong effects against cancer cells from colorectal, breast, and prostate cancers. Remarkably, it affected gene expression in immune cells, boosting elements that help fight infections and support the body's defenses. Notably, VD-LP did a great job slowing tumor growth in mice and improved their survival rates without causing adverse effects like hypercalcemia, which is often a concern with regular vitamin D3 use. This evidence indicates that liposomal encapsulation of vitamin D3 could offer an effective cancer treatment strategy while minimizing unwanted side effects. We believe this may pave the way for further research and clinical applications, showcasing vitamin D3 as a valuable addition to cancer therapy. 9 Benefits cancer patients Most Useful Review 1 people found this helpful This is the best vitamin D3 I prescribe for my cancer patients. It's vital for those diagnosed with cancer. I usually recommend one capsule per week, or sometimes one daily for cancer patients, as it rapidly raises serum calcidiol levels and is safe with regular lab tests.
NOW Foods, Chewable Vitamin D-3, Natural Fruit Flavor, 1,000 IU, 180 Chewables	7.5	8
8 Vitamin D3 offers anti-cancer benefits Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Ezcurra-Hualde M, Zalba S, Bella Á, Arrizabalaga L, Risson A, et al. Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Front Immunol. 2025;16:1529007. doi:10.3389/fimmu.2025.1529007 We investigated the potential of vitamin D3, also known as cholecalciferol, in combating cancer while addressing concerns about its toxicity at higher doses. This study focused on enhancing the effectiveness of vitamin D3 through a clever method called liposomal encapsulation, which helps minimize side effects. We prepared liposomal vitamin D3 (VD-LP) and conducted various tests to understand its capabilities. We found that this encapsulated form not only maintained high efficiency but also demonstrated improved stability. Our analyses showed that VD-LP had strong effects against cancer cells from colorectal, breast, and prostate cancers. Remarkably, it affected gene expression in immune cells, boosting elements that help fight infections and support the body's defenses. Notably, VD-LP did a great job slowing tumor growth in mice and improved their survival rates without causing adverse effects like hypercalcemia, which is often a concern with regular vitamin D3 use. This evidence indicates that liposomal encapsulation of vitamin D3 could offer an effective cancer treatment strategy while minimizing unwanted side effects. We believe this may pave the way for further research and clinical applications, showcasing vitamin D3 as a valuable addition to cancer therapy. 9 Boosts mood Most Useful Review This vitamin D3 from a reputable brand effectively elevates my mood and energy levels and assists with depression. It is crucial for bone growth and also helps regulate cancer cell growth.
Life Extension, Vitamin D3 with Sea-Iodine, 125 mcg (5,000 IU), 60 Capsules	7.4	7.9
9 Iodine treatment aids recurrent cancer Case report of the first use of a hydrogel rectal spacer for prostate cancer reirradiation via LDR brachytherapy: applications and technical notes. Lazrek A, Finocchi Ghersi S, Petre A, Houabes S, Serre AA, et al. Case report of the first use of a hydrogel rectal spacer for prostate cancer reirradiation via LDR brachytherapy: applications and technical notes. Front Oncol. 2025;15:1494304. doi:10.3389/fonc.2025.1494304 We observed a compelling case where a biodegradable hydrogel spacer was used alongside iodine-125 brachytherapy to treat recurrent prostate cancer. This innovative approach involved placing the spacer to create space between the prostate and the rectum, which significantly reduced radiation exposure to healthy tissues during the treatment. Following initial external beam radiotherapy in 2015, the patient showed signs of local recurrence by 2022. To address this, the treatment plan included not just the iodine-125 brachytherapy but also the hydrogel spacer, which was placed in January 2024 just before the radiation treatment. Six months later, we noted a remarkable drop in the patient’s prostate-specific antigen (PSA) levels, indicating a positive response to the treatment. This case showcases the potential benefits of using iodine treatment in combination with advanced techniques like hydrogel spacers. The results suggest that this method not only improves the effectiveness of therapy but also ensures higher safety by protecting adjacent tissues from unnecessary radiation damage. Overall, we find this integration of technology highly beneficial for managing recurrent cancer challenges. 7.5 Aids bone health Most Useful Review I take vitamin D3 constantly; it ensures normal growth and development of bones, preventing rickets and osteoporosis. It regulates mineral metabolism, promotes muscle tone, improves immunity, and is vital for thyroid function and blood clotting. It also helps restore protective sheaths around nerves and regulates blood pressure and heartbeat while inhibiting cancer cell growth. Good company and optimal dosage for winter. You can take it every other day if necessary.
NOW Foods, Vitamin D-3, High Potency, 5,000 IU, 120 Softgels	7.5	7.7
8 Vitamin D3 offers anti-cancer benefits Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Ezcurra-Hualde M, Zalba S, Bella Á, Arrizabalaga L, Risson A, et al. Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Front Immunol. 2025;16:1529007. doi:10.3389/fimmu.2025.1529007 We investigated the potential of vitamin D3, also known as cholecalciferol, in combating cancer while addressing concerns about its toxicity at higher doses. This study focused on enhancing the effectiveness of vitamin D3 through a clever method called liposomal encapsulation, which helps minimize side effects. We prepared liposomal vitamin D3 (VD-LP) and conducted various tests to understand its capabilities. We found that this encapsulated form not only maintained high efficiency but also demonstrated improved stability. Our analyses showed that VD-LP had strong effects against cancer cells from colorectal, breast, and prostate cancers. Remarkably, it affected gene expression in immune cells, boosting elements that help fight infections and support the body's defenses. Notably, VD-LP did a great job slowing tumor growth in mice and improved their survival rates without causing adverse effects like hypercalcemia, which is often a concern with regular vitamin D3 use. This evidence indicates that liposomal encapsulation of vitamin D3 could offer an effective cancer treatment strategy while minimizing unwanted side effects. We believe this may pave the way for further research and clinical applications, showcasing vitamin D3 as a valuable addition to cancer therapy. 7.5 Supports cancer treatment Most Useful Review 4809 people found this helpful Vitamine D is crucial for bone health and has anti-cancer benefits. If your 25 (OH) D level is 20 or less, it's advisable to start with 5000 IU daily. For levels 21-30, take 2,000 IU, and if it's 31-40, take 1000 IU daily. After three months, retest. The optimal level is 50-70. Vitamin D supplementation raises levels effectively without odour. Sunlight aids production, but sunscreen can hinder it. This supplement has improved my health significantly. Happy shopping!
Jarrow Formulas, Vitamin D3, 125 mcg (5,000 IU), 100 Softgels	7.3	7.9
5 Vitamin D's role in breast disease Levels of Serum 25-Hydroxy Vitamin D in Benign and Malignant Breast Disease Patients: An Observational Study. Soni D, Tiwari A, Kushwah PS, Dubey S, Khan S. Levels of Serum 25-Hydroxy Vitamin D in Benign and Malignant Breast Disease Patients: An Observational Study. Cureus. 2025;17:e78283. doi:10.7759/cureus.78283 We conducted an observational study to examine the levels of vitamin D in female patients with benign and malignant breast diseases. The research aimed to determine if there is a significant difference in vitamin D levels between those with non-cancerous conditions and those diagnosed with breast cancer. During the study, we analyzed adult female patients admitted to a surgical department. Importantly, we excluded those who had taken vitamin D supplements recently or who had prior vitamin D deficiencies. By measuring serum vitamin D levels through a specific testing method, we were able to gather meaningful data about their relationship to breast health. Our findings indicated a notable difference in average vitamin D levels when comparing the two groups. This suggests that inadequate vitamin D could be linked to an increased risk of developing breast cancer. Therefore, we explored the potential benefits of vitamin D supplementation as a preventive measure against breast cancer—though we acknowledge that larger and more controlled studies are essential to draw firm conclusions. At the same time, we recognize that vitamin D has effects beyond bone health, and it is crucial to consider these broader impacts when discussing its role in cancer risk. 9 Cancer cell inhibition Most Useful Review Vitamin D supports cell growth, restores immunity, and inhibits the growth of cancer cells, making it essential for overall health.
Superior Source, D3, Extra Strength, 125 mcg (5,000 IU), 100 MicroLingual® Instant Dissolve Tablets	7.3	7.8
5 Vitamin D's role in breast disease Levels of Serum 25-Hydroxy Vitamin D in Benign and Malignant Breast Disease Patients: An Observational Study. Soni D, Tiwari A, Kushwah PS, Dubey S, Khan S. Levels of Serum 25-Hydroxy Vitamin D in Benign and Malignant Breast Disease Patients: An Observational Study. Cureus. 2025;17:e78283. doi:10.7759/cureus.78283 We conducted an observational study to examine the levels of vitamin D in female patients with benign and malignant breast diseases. The research aimed to determine if there is a significant difference in vitamin D levels between those with non-cancerous conditions and those diagnosed with breast cancer. During the study, we analyzed adult female patients admitted to a surgical department. Importantly, we excluded those who had taken vitamin D supplements recently or who had prior vitamin D deficiencies. By measuring serum vitamin D levels through a specific testing method, we were able to gather meaningful data about their relationship to breast health. Our findings indicated a notable difference in average vitamin D levels when comparing the two groups. This suggests that inadequate vitamin D could be linked to an increased risk of developing breast cancer. Therefore, we explored the potential benefits of vitamin D supplementation as a preventive measure against breast cancer—though we acknowledge that larger and more controlled studies are essential to draw firm conclusions. At the same time, we recognize that vitamin D has effects beyond bone health, and it is crucial to consider these broader impacts when discussing its role in cancer risk. 9 Improved health status Most Useful Review 2 people found this helpful I trust this D3 as I had low levels and a history of cancer. It is the only D3 I take daily, along with K2 by Life Extension. Superior Source works well, and my D3 levels rose from 20 to 65-68 over time. It takes a while if you're depleted, but I feel better overall with fewer aches now that my D3 levels are normal.
Life Extension, Vitamin D3, 125 mcg (5,000 IU), 60 Softgels	7.5	7.6
8 Vitamin D3 offers anti-cancer benefits Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Ezcurra-Hualde M, Zalba S, Bella Á, Arrizabalaga L, Risson A, et al. Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Front Immunol. 2025;16:1529007. doi:10.3389/fimmu.2025.1529007 We investigated the potential of vitamin D3, also known as cholecalciferol, in combating cancer while addressing concerns about its toxicity at higher doses. This study focused on enhancing the effectiveness of vitamin D3 through a clever method called liposomal encapsulation, which helps minimize side effects. We prepared liposomal vitamin D3 (VD-LP) and conducted various tests to understand its capabilities. We found that this encapsulated form not only maintained high efficiency but also demonstrated improved stability. Our analyses showed that VD-LP had strong effects against cancer cells from colorectal, breast, and prostate cancers. Remarkably, it affected gene expression in immune cells, boosting elements that help fight infections and support the body's defenses. Notably, VD-LP did a great job slowing tumor growth in mice and improved their survival rates without causing adverse effects like hypercalcemia, which is often a concern with regular vitamin D3 use. This evidence indicates that liposomal encapsulation of vitamin D3 could offer an effective cancer treatment strategy while minimizing unwanted side effects. We believe this may pave the way for further research and clinical applications, showcasing vitamin D3 as a valuable addition to cancer therapy. 9 Cancer risk reduction Most Useful Review 4 people found this helpful Vitamin D is the most potent steroid hormone and possesses exceptional anticancer properties. Achieving a blood vitamin D level of 50 ng/ml decreases cancer risk by 75% overall, breast cancer risk by 70%, and colon cancer risk by 67%. It’s crucial to increase vitamin D levels before illness, as starting post-symptoms has no effect on severity. A study from 2018 found that women with 25 (OH) D concentrations of 60 ng/ml or greater had an 80% lower risk of developing breast cancer compared to those with levels below 20 ng/ml. Vitamin D is vital for reducing cancer risks and should be maintained at optimal levels.
NOW Foods, Vitamin D-3, 400 IU, 180 Softgels	7.5	6.7
8 Vitamin D3 offers anti-cancer benefits Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Ezcurra-Hualde M, Zalba S, Bella Á, Arrizabalaga L, Risson A, et al. Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Front Immunol. 2025;16:1529007. doi:10.3389/fimmu.2025.1529007 We investigated the potential of vitamin D3, also known as cholecalciferol, in combating cancer while addressing concerns about its toxicity at higher doses. This study focused on enhancing the effectiveness of vitamin D3 through a clever method called liposomal encapsulation, which helps minimize side effects. We prepared liposomal vitamin D3 (VD-LP) and conducted various tests to understand its capabilities. We found that this encapsulated form not only maintained high efficiency but also demonstrated improved stability. Our analyses showed that VD-LP had strong effects against cancer cells from colorectal, breast, and prostate cancers. Remarkably, it affected gene expression in immune cells, boosting elements that help fight infections and support the body's defenses. Notably, VD-LP did a great job slowing tumor growth in mice and improved their survival rates without causing adverse effects like hypercalcemia, which is often a concern with regular vitamin D3 use. This evidence indicates that liposomal encapsulation of vitamin D3 could offer an effective cancer treatment strategy while minimizing unwanted side effects. We believe this may pave the way for further research and clinical applications, showcasing vitamin D3 as a valuable addition to cancer therapy. 9 Essential for adults Most Useful Review 6 people found this helpful Contrary to popular belief, vitamin D3 is crucial for adults, especially in areas with limited sunlight. It aids in the rapid absorption of magnesium and calcium, fortifies immunity, and is vital for bone health while preventing the growth of cancer cells.
Dha
NOW Foods, Double Strength DHA-500 Fish Oil, 180 Softgels	7.8	8
9 DHA affects colorectal cancer pathways Dietary polyunsaturated fatty acids affect PPARγ promoter methylation status and regulate the PPARγ/COX2 pathway in some colorectal cancer cell lines. Babaeenezhad E, Khosravi P, Moradi Sarabi M. Dietary polyunsaturated fatty acids affect PPARγ promoter methylation status and regulate the PPARγ/COX2 pathway in some colorectal cancer cell lines. Genes Nutr. 2025;20:2. doi:10.1186/s12263-025-00764-x We set out to explore how docosahexaenoic acid (DHA), a type of omega-3 fatty acid, affects colorectal cancer (CRC) cells. In this study, we treated five different colorectal cancer cell lines with varying concentrations of DHA, along with other fatty acids like eicosapentaenoic acid (EPA) and linoleic acid (LA). This allowed us to see if DHA could impact the methylation patterns of the PPARγ promoter, a key player in cancer regulation, and affect the relationship between PPARγ and COX2, two important molecules involved in cancer growth. Our findings revealed that DHA significantly altered the methylation status in some cell lines, effectively demethylating specific regions of the PPARγ promoter. We observed that this demethylation was linked to an increase in the expression of PPARγ in cells where it was hemimethylated. Interestingly, DHA not only boosted PPARγ levels but also downregulated COX2 across all CRC cell lines tested. This suggests that DHA might have a role in reducing inflammatory signals linked to cancer progression. The overall impact seemed to vary depending on the type of cancer cell we were working with, indicating a cell type-dependent effect of DHA. Notably, we found that DHA was more effective than EPA or LA in modulating the PPARγ promoter. This research shows promising potential for DHA in colorectal cancer treatment and highlights its importance in dietary considerations for cancer management. 7.5 Brain activity support Most Useful Review Docosahexaenoic acid is a vital omega-3 fatty acid for health. Consuming at least 250 mg of DHA daily may lower the risk of cancer. I purchased this for my mother to support her brain function.
Lactoferrin
Jarrow Formulas, Lactoferrin, Freeze Dried, 250 mg, 60 Capsules	7.6	8.2
8 Lactoferrin peptide shows anticancer potential Lactoferrin-Derived Peptide Chimera Induces Caspase-Independent Cell Death in Multiple Myeloma. Jang YS, Dehkohneh SB, Lim J, Kim J, Ahn D, et al. Lactoferrin-Derived Peptide Chimera Induces Caspase-Independent Cell Death in Multiple Myeloma. Cells. 2025;14. doi:10.3390/cells14030217 We explored the potential of a synthetic peptide, derived from lactoferrin, to treat multiple myeloma, a type of cancer affecting plasma cells in the bone marrow. This peptide mimics the antibacterial properties of lactoferrin and appears to have anticancer effects as well. In our experiments, the lactoferrin-derived chimera effectively inhibited the growth of multiple myeloma cell lines, including MM1S, MM1R, and RPMI8226. Notably, it induced both early and late stages of cell death in these cancer cells while sparing normal blood cells from damage. Further analysis revealed that this peptide had a significant impact on the expression of genes tied to cell survival and apoptosis. We discovered that it triggers oxidative stress, leading to a generation of reactive oxygen species and mitochondrial dysfunction in cancer cells. Importantly, while the peptide did not cause the typical caspase-dependent cell death we often observe in cancer treatments, it did promote a different form of apoptosis via the nuclear translocation of specific factors like apoptosis-inducing factor and endonuclease G. Overall, this lactoferrin-derived peptide chimera shows promise in inducing a unique, caspase-independent form of cell death in multiple myeloma, suggesting it could be an effective new addition to cancer therapies. 7.5 Breast cancer growth Most Useful Review 43 people found this helpful I acquired this supplement for three main reasons: to protect against viruses and fungi, enhance iron absorption, and improve intestinal health. I learned that lactoferrin may inhibit the growth of breast cancer cells. However, I feel one course may not suffice to see significant results. Wishing everyone good health and a positive mindset!
Garlic
Dr. Mercola, Fermented Black Garlic, 60 Capsules	7.5	8.3
9 Garlic's allicin shows anticancer potential Harnessing Therapeutic Potential of Allicin Against Cancer: An Exploratory Review. Saini A, Saini V, Deswal G, Chopra B, Grewal AS, et al. Harnessing Therapeutic Potential of Allicin Against Cancer: An Exploratory Review. Anticancer Agents Med Chem. 2025. doi:10.2174/0118715206343978241223080625 We investigated the effects of allicin, a compound derived from garlic, on various types of cancer. Our literature review pulled input from trustworthy sources, including well-regarded medical databases. The study primarily aimed to assess whether allicin could inhibit cancer cell growth and its broader therapeutic potential. Through our exploration, we found that allicin shows considerable promise in fighting cancer. Specifically, cell line studies demonstrated that this compound can significantly reduce the growth of cancer cells across different types, including breast, pancreatic, liver, and colorectal cancers. This evidence highlights allicin's potential as an effective treatment option. We also took a closer look at existing patent statistics and clinical studies to better understand allicin's advantages. The data reinforced that allicin stands out for its various therapeutic properties, making it an important focal point for future cancer research. Overall, we are excited to share how garlic, through its active compound allicin, can potentially play a role in cancer therapies, showing real hope in the ongoing battle against this disease. 7.5 Natural cancer aid Most Useful Review 11 people found this helpful Excellent! Black garlic is natural, slightly processed with heat and warmth, containing no chemicals. It offers numerous health benefits, including boosting immunity, aiding liver repair, high antioxidant content, controlling insulin secretion, fighting cancer, enhancing heart health, improving brain function, and boosting testosterone levels.
Kyolic, Aged Garlic Extract™, Cardiovascular Health, Original Formula 100, 600 mg, 300 Capsules (300 mg Per Capsule)	7.5	8.2
9 Garlic's allicin shows anticancer potential Harnessing Therapeutic Potential of Allicin Against Cancer: An Exploratory Review. Saini A, Saini V, Deswal G, Chopra B, Grewal AS, et al. Harnessing Therapeutic Potential of Allicin Against Cancer: An Exploratory Review. Anticancer Agents Med Chem. 2025. doi:10.2174/0118715206343978241223080625 We investigated the effects of allicin, a compound derived from garlic, on various types of cancer. Our literature review pulled input from trustworthy sources, including well-regarded medical databases. The study primarily aimed to assess whether allicin could inhibit cancer cell growth and its broader therapeutic potential. Through our exploration, we found that allicin shows considerable promise in fighting cancer. Specifically, cell line studies demonstrated that this compound can significantly reduce the growth of cancer cells across different types, including breast, pancreatic, liver, and colorectal cancers. This evidence highlights allicin's potential as an effective treatment option. We also took a closer look at existing patent statistics and clinical studies to better understand allicin's advantages. The data reinforced that allicin stands out for its various therapeutic properties, making it an important focal point for future cancer research. Overall, we are excited to share how garlic, through its active compound allicin, can potentially play a role in cancer therapies, showing real hope in the ongoing battle against this disease. 9 Cancer prevention aid Most Useful Review 1 people found this helpful This supplement supports cardiovascular health, lowers bad cholesterol, and prevents atherosclerosis, heart attacks, and blood clots. Thanks to allicin, garlic may also prevent cancer development. It has no negative side effects, making it ideal for heart health.
NOW Foods, Garlic 5000, 500 mg, 90 Tablets	7.5	8
9 Garlic's allicin shows anticancer potential Harnessing Therapeutic Potential of Allicin Against Cancer: An Exploratory Review. Saini A, Saini V, Deswal G, Chopra B, Grewal AS, et al. Harnessing Therapeutic Potential of Allicin Against Cancer: An Exploratory Review. Anticancer Agents Med Chem. 2025. doi:10.2174/0118715206343978241223080625 We investigated the effects of allicin, a compound derived from garlic, on various types of cancer. Our literature review pulled input from trustworthy sources, including well-regarded medical databases. The study primarily aimed to assess whether allicin could inhibit cancer cell growth and its broader therapeutic potential. Through our exploration, we found that allicin shows considerable promise in fighting cancer. Specifically, cell line studies demonstrated that this compound can significantly reduce the growth of cancer cells across different types, including breast, pancreatic, liver, and colorectal cancers. This evidence highlights allicin's potential as an effective treatment option. We also took a closer look at existing patent statistics and clinical studies to better understand allicin's advantages. The data reinforced that allicin stands out for its various therapeutic properties, making it an important focal point for future cancer research. Overall, we are excited to share how garlic, through its active compound allicin, can potentially play a role in cancer therapies, showing real hope in the ongoing battle against this disease. 9 Strengthens immunity Most Useful Review 19 people found this helpful Garlic is excellent for the gut, enhancing enzyme secretion and digestion, while strengthening the immune system and improving cardiovascular health. It lowers cholesterol, aids high blood pressure, and reduces cancer risks. I firmly believe in garlic’s healing properties.
NOW Foods, Odorless Garlic, Concentrated Extract, 50 mg, 250 Softgels (25 mg per Softgel)	7.5	7.9
9 Garlic's allicin shows anticancer potential Harnessing Therapeutic Potential of Allicin Against Cancer: An Exploratory Review. Saini A, Saini V, Deswal G, Chopra B, Grewal AS, et al. Harnessing Therapeutic Potential of Allicin Against Cancer: An Exploratory Review. Anticancer Agents Med Chem. 2025. doi:10.2174/0118715206343978241223080625 We investigated the effects of allicin, a compound derived from garlic, on various types of cancer. Our literature review pulled input from trustworthy sources, including well-regarded medical databases. The study primarily aimed to assess whether allicin could inhibit cancer cell growth and its broader therapeutic potential. Through our exploration, we found that allicin shows considerable promise in fighting cancer. Specifically, cell line studies demonstrated that this compound can significantly reduce the growth of cancer cells across different types, including breast, pancreatic, liver, and colorectal cancers. This evidence highlights allicin's potential as an effective treatment option. We also took a closer look at existing patent statistics and clinical studies to better understand allicin's advantages. The data reinforced that allicin stands out for its various therapeutic properties, making it an important focal point for future cancer research. Overall, we are excited to share how garlic, through its active compound allicin, can potentially play a role in cancer therapies, showing real hope in the ongoing battle against this disease. 7.5 Boosts immunity Most Useful Review 7 people found this helpful Increasing my garlic intake significantly has been effective. This small, easy-to-swallow pill offers excellent anti-cancer effects and boosts my immunity. I intend to continue taking it.
NOW Foods, Garlic Oil, 1,500 mg, 250 Softgels	7.5	7.4
9 Garlic's allicin shows anticancer potential Harnessing Therapeutic Potential of Allicin Against Cancer: An Exploratory Review. Saini A, Saini V, Deswal G, Chopra B, Grewal AS, et al. Harnessing Therapeutic Potential of Allicin Against Cancer: An Exploratory Review. Anticancer Agents Med Chem. 2025. doi:10.2174/0118715206343978241223080625 We investigated the effects of allicin, a compound derived from garlic, on various types of cancer. Our literature review pulled input from trustworthy sources, including well-regarded medical databases. The study primarily aimed to assess whether allicin could inhibit cancer cell growth and its broader therapeutic potential. Through our exploration, we found that allicin shows considerable promise in fighting cancer. Specifically, cell line studies demonstrated that this compound can significantly reduce the growth of cancer cells across different types, including breast, pancreatic, liver, and colorectal cancers. This evidence highlights allicin's potential as an effective treatment option. We also took a closer look at existing patent statistics and clinical studies to better understand allicin's advantages. The data reinforced that allicin stands out for its various therapeutic properties, making it an important focal point for future cancer research. Overall, we are excited to share how garlic, through its active compound allicin, can potentially play a role in cancer therapies, showing real hope in the ongoing battle against this disease. 9 Effective cancer fighter Most Useful Review Garlic is a remarkable superfood that boosts immunity and fights infections; it’s a potent cancer fighter. I take these softgels with whey protein for better absorption. However, I do experience garlic burps, unlike a different garlic product from Now Foods that doesn't cause this issue.
Milk Thistle Silymarin
NOW Foods, Milk Thistle Extract with Turmeric, 150 mg, 120 Veg Capsules	7.6	8.2
9 Investigating silibinin's cancer treatment role Anti-Tumor Activity and Mechanism of Silibinin Based on Network Pharmacology and Experimental Verification. Li P, Wang D, Yang X, Liu C, Li X, et al. Anti-Tumor Activity and Mechanism of Silibinin Based on Network Pharmacology and Experimental Verification. Molecules. 2024;29. doi:10.3390/molecules29081901 We aimed to uncover how silibinin, a compound from milk thistle, impacts cancer, specifically in adenoid cystic carcinoma cells and Balb/c nude mice. The study identified 75 key targets linked to tumor growth and showcased that silibinin significantly reduced cell viability, proliferation, and migration. Additionally, it induced cancer cell death and inhibited tumor growth in live subjects. Our findings highlighted how silibinin acts on specific proteins affecting cancer pathways, offering valuable insights into its potential as an anti-tumor treatment. 9 Aids liver function Most Useful Review 3 people found this helpful In traditional medicine, silymarin is known for treating liver and gallbladder conditions, promoting lactation, and preventing cancer. It helps the liver detoxify from poisons, such as snakebites. My uncle, who was a heavy drinker, took it for three months, resulting in a notable improvement in his skin tone and overall health.
NOW Foods, Milk Thistle Extract, Double Strength, 300 mg, 200 Veg Capsules	7.6	7.8
9 Investigating silibinin's cancer treatment role Anti-Tumor Activity and Mechanism of Silibinin Based on Network Pharmacology and Experimental Verification. Li P, Wang D, Yang X, Liu C, Li X, et al. Anti-Tumor Activity and Mechanism of Silibinin Based on Network Pharmacology and Experimental Verification. Molecules. 2024;29. doi:10.3390/molecules29081901 We aimed to uncover how silibinin, a compound from milk thistle, impacts cancer, specifically in adenoid cystic carcinoma cells and Balb/c nude mice. The study identified 75 key targets linked to tumor growth and showcased that silibinin significantly reduced cell viability, proliferation, and migration. Additionally, it induced cancer cell death and inhibited tumor growth in live subjects. Our findings highlighted how silibinin acts on specific proteins affecting cancer pathways, offering valuable insights into its potential as an anti-tumor treatment. 9 Natural hepatoprotector Most Useful Review 18 people found this helpful Silymarin, derived from milk thistle, is a non-toxic natural substance known for its hepatoprotective and antioxidant properties. It exhibits anti-cancer effects, improves liver function, and has been extensively studied in over 3,000 scientific papers. Its zero toxicity has been noted in various clinical studies.
Vitamin A
Nature's Way, Vitamin A, 3,000 mcg, 100 Softgels	7.4	8.3
9 Vitamin A aids ovarian cancer treatment All-trans Retinoic Acid Sensitizes Epithelial Ovarian Cancer to PARP Inhibition after Exposure to Cisplatin. Mei B, Li J, Wang D, Feng L, Huang J, et al. All-trans Retinoic Acid Sensitizes Epithelial Ovarian Cancer to PARP Inhibition after Exposure to Cisplatin. Mol Cancer Ther. 2025;24:453. doi:10.1158/1535-7163.MCT-24-0140 We focused on how all-trans retinoic acid (ATRA), a form of vitamin A, helps combat resistance in epithelial ovarian cancer (EOC) when combined with standard platinum-based chemotherapy, such as cisplatin. Our findings indicate that ATRA effectively reduced PARP inhibitor resistance in EOC cells, both in lab settings and in animal models. Additionally, using ATRA along with ongoing treatment improved survival rates in EOC-bearing mice. This suggests that ATRA could be an important part of future therapies for enhancing the effectiveness of existing treatments. 9 Comprehensive cancer prevention Most Useful Review Vitamin A enhances the body's resistance to infections and inflammatory diseases. It is essential for proper vision and has powerful antioxidant properties that contribute to cancer prevention. A great option for support in maintaining health!
NOW Foods, Vitamin A, 25,000 IU, 250 Softgels	7.4	8.2
9 Vitamin A aids ovarian cancer treatment All-trans Retinoic Acid Sensitizes Epithelial Ovarian Cancer to PARP Inhibition after Exposure to Cisplatin. Mei B, Li J, Wang D, Feng L, Huang J, et al. All-trans Retinoic Acid Sensitizes Epithelial Ovarian Cancer to PARP Inhibition after Exposure to Cisplatin. Mol Cancer Ther. 2025;24:453. doi:10.1158/1535-7163.MCT-24-0140 We focused on how all-trans retinoic acid (ATRA), a form of vitamin A, helps combat resistance in epithelial ovarian cancer (EOC) when combined with standard platinum-based chemotherapy, such as cisplatin. Our findings indicate that ATRA effectively reduced PARP inhibitor resistance in EOC cells, both in lab settings and in animal models. Additionally, using ATRA along with ongoing treatment improved survival rates in EOC-bearing mice. This suggests that ATRA could be an important part of future therapies for enhancing the effectiveness of existing treatments. 9 Improved gastritis Most Useful Review 56 people found this helpful The required amount of Vitamin A varies significantly depending on individual circumstances. Those with dry eye, asthma, gastrointestinal issues, or a family history of cancer may require more. I gradually increased my intake to 100,000 units for a year, which cleared my persistent red sore gastritis, eliminating the need for medication.
NOW Foods, Vitamin A, 10,000 IU, 100 Softgels	7.4	7.9
9 Vitamin A aids ovarian cancer treatment All-trans Retinoic Acid Sensitizes Epithelial Ovarian Cancer to PARP Inhibition after Exposure to Cisplatin. Mei B, Li J, Wang D, Feng L, Huang J, et al. All-trans Retinoic Acid Sensitizes Epithelial Ovarian Cancer to PARP Inhibition after Exposure to Cisplatin. Mol Cancer Ther. 2025;24:453. doi:10.1158/1535-7163.MCT-24-0140 We focused on how all-trans retinoic acid (ATRA), a form of vitamin A, helps combat resistance in epithelial ovarian cancer (EOC) when combined with standard platinum-based chemotherapy, such as cisplatin. Our findings indicate that ATRA effectively reduced PARP inhibitor resistance in EOC cells, both in lab settings and in animal models. Additionally, using ATRA along with ongoing treatment improved survival rates in EOC-bearing mice. This suggests that ATRA could be an important part of future therapies for enhancing the effectiveness of existing treatments. 9 Aids wound healing Most Useful Review 1 people found this helpful Vitamin A plays a vital role in maintaining the integrity of mucous membranes and skin. It promotes rapid healing of wounds and prevents keratinisation and death of skin cells. This vitamin is essential for protein synthesis in the body and is particularly effective for eye health, especially night vision. Moreover, it is a powerful antioxidant beneficial in cancer treatment and prevention. It also protects the skin from sun damage, making it advisable to take before beach holidays. It influences progesterone synthesis, impacting reproductive function and libido. Daily intake with food enhances absorption.
Omega 3 Fish Oil
Natrol, Omega-3 Fish Oil, Lemon, 1,000 mg, 150 Softgels	7.4	8.3
8 Omega-3 diet slows cancer progression High Omega-3, Low Omega-6 Diet With Fish Oil for Men With Prostate Cancer on Active Surveillance: The CAPFISH-3 Randomized Clinical Trial. Aronson WJ, Grogan T, Liang P, Jardack P, Liddell AR, et al. High Omega-3, Low Omega-6 Diet With Fish Oil for Men With Prostate Cancer on Active Surveillance: The CAPFISH-3 Randomized Clinical Trial. J Clin Oncol. 2025;43:800. doi:10.1200/JCO.24.00608 We explored the impact of a high omega-3, low omega-6 diet with fish oil on men with prostate cancer under active surveillance. In a year-long study involving 100 participants, those following the omega-rich regimen showed a notable 15% decrease in the Ki-67 index, a key marker for cancer progression. In contrast, the control group experienced an increase in this index. While the diet showed promise in slowing down potential cancer growth, no significant differences were noted in other cancer-related measurements. Our findings encourage further research on dietary strategies in prostate cancer management. 7.5 Cancer prevention benefits Most Useful Review 33 people found this helpful "Mega" omega is wonderful fish oil of excellent quality! It contains a natural fish oil concentrate rich in polyunsaturated fatty acids, which dramatically lower cholesterol levels, supporting cardiovascular health. Omega 3 is noted for slowing tumour development and is effective in preventing cancer. It aids in skin disease treatment and improves healing. This supplement also normalises digestion and fat metabolism, alleviates arthritis pain, and is essential for brain activity. Recommended dosage is 3-4 capsules daily with meals.
NOW Foods, Omega-3 Fish Oil, 1000 mg, 180 EPA - 120 DHA, Odor Controlled, Enteric Coated, 90 Softgels	7.4	8.1
8 Omega-3 diet slows cancer progression High Omega-3, Low Omega-6 Diet With Fish Oil for Men With Prostate Cancer on Active Surveillance: The CAPFISH-3 Randomized Clinical Trial. Aronson WJ, Grogan T, Liang P, Jardack P, Liddell AR, et al. High Omega-3, Low Omega-6 Diet With Fish Oil for Men With Prostate Cancer on Active Surveillance: The CAPFISH-3 Randomized Clinical Trial. J Clin Oncol. 2025;43:800. doi:10.1200/JCO.24.00608 We explored the impact of a high omega-3, low omega-6 diet with fish oil on men with prostate cancer under active surveillance. In a year-long study involving 100 participants, those following the omega-rich regimen showed a notable 15% decrease in the Ki-67 index, a key marker for cancer progression. In contrast, the control group experienced an increase in this index. While the diet showed promise in slowing down potential cancer growth, no significant differences were noted in other cancer-related measurements. Our findings encourage further research on dietary strategies in prostate cancer management. 9 Cancer prevention Most Useful Review Omega is of high quality, increases immunity, has a pleasant scent, and offers great benefits. I believe it helps prevent cancer and comes in a tightly sealed package. It serves as a strong antioxidant and cleanses the body.
Solgar, Omega 3, EPA & DHA, Triple Strength, 950 mg, 100 Softgels	7.3	8.2
8 Omega-3 diet slows cancer progression High Omega-3, Low Omega-6 Diet With Fish Oil for Men With Prostate Cancer on Active Surveillance: The CAPFISH-3 Randomized Clinical Trial. Aronson WJ, Grogan T, Liang P, Jardack P, Liddell AR, et al. High Omega-3, Low Omega-6 Diet With Fish Oil for Men With Prostate Cancer on Active Surveillance: The CAPFISH-3 Randomized Clinical Trial. J Clin Oncol. 2025;43:800. doi:10.1200/JCO.24.00608 We explored the impact of a high omega-3, low omega-6 diet with fish oil on men with prostate cancer under active surveillance. In a year-long study involving 100 participants, those following the omega-rich regimen showed a notable 15% decrease in the Ki-67 index, a key marker for cancer progression. In contrast, the control group experienced an increase in this index. While the diet showed promise in slowing down potential cancer growth, no significant differences were noted in other cancer-related measurements. Our findings encourage further research on dietary strategies in prostate cancer management. 7.5 Cancer cell control Most Useful Review 3 people found this helpful Omega-3 fatty acids significantly impact health by ensuring a correct ratio with omega-6. The typical diet skews far towards omega-6, causing issues like blood clots, hypertension, and increased cancer cell proliferation. Countries with better ratios see improved health outcomes, highlighting the importance of omega-3 in preventing cancer.
NOW Foods, Omega-3 Fish Oil, 1,000 mg, 180 EPA - 120 DHA, 100 Softgels	7.4	7.8
8 Omega-3 diet slows cancer progression High Omega-3, Low Omega-6 Diet With Fish Oil for Men With Prostate Cancer on Active Surveillance: The CAPFISH-3 Randomized Clinical Trial. Aronson WJ, Grogan T, Liang P, Jardack P, Liddell AR, et al. High Omega-3, Low Omega-6 Diet With Fish Oil for Men With Prostate Cancer on Active Surveillance: The CAPFISH-3 Randomized Clinical Trial. J Clin Oncol. 2025;43:800. doi:10.1200/JCO.24.00608 We explored the impact of a high omega-3, low omega-6 diet with fish oil on men with prostate cancer under active surveillance. In a year-long study involving 100 participants, those following the omega-rich regimen showed a notable 15% decrease in the Ki-67 index, a key marker for cancer progression. In contrast, the control group experienced an increase in this index. While the diet showed promise in slowing down potential cancer growth, no significant differences were noted in other cancer-related measurements. Our findings encourage further research on dietary strategies in prostate cancer management. 7.5 Antioxidant properties Most Useful Review 122 people found this helpful Omega-3 has been beneficial for various systems in the body, improving memory, and normalising metabolism. A shortage can lead to atherosclerosis and other health issues. These fatty acids also have antioxidant properties that may help prevent cancer. I find Omega-3 purifies blood vessels and improves conditions such as allergies, skin diseases, and diabetes. Overall, it's vital for maintaining good health.
Vitamin K
Doctor's Best, Natural Vitamin K2 MK-7 , 45 mcg, 60 Veggie Caps	7.6	8.1
9 PIVKA-II shows promise for HCC PIVKA-II as a surrogate biomarker for therapeutic response in Non-AFP-secreting hepatocellular carcinoma. Chen SC, Ho HL, Liu CA, Hung YP, Chiang NJ, et al. PIVKA-II as a surrogate biomarker for therapeutic response in Non-AFP-secreting hepatocellular carcinoma. BMC Cancer. 2025;25:199. doi:10.1186/s12885-025-13568-4 We aimed to discover how well PIVKA-II can predict treatment response in patients with non-AFP-secreting hepatocellular carcinoma (HCC) receiving systemic therapy. By measuring PIVKA-II levels and assessing imaging after 8-12 weeks of treatment, we found a connection between PIVKA-II levels, tumor size, and treatment outcomes. The study revealed a promising “50-50 rule” that can indicate prognosis based on PIVKA-II changes, making it a valuable marker for HCC treatment success. 7.5 Post-surgery recovery Most Useful Review After thyroid cancer surgery, I regularly consume this vitamin K combination and have noticed significant improvements in my health.
NOW Foods, MK-7 Vitamin K-2 , 100 mcg, 120 Veg Capsules	7.6	8
9 PIVKA-II shows promise for HCC PIVKA-II as a surrogate biomarker for therapeutic response in Non-AFP-secreting hepatocellular carcinoma. Chen SC, Ho HL, Liu CA, Hung YP, Chiang NJ, et al. PIVKA-II as a surrogate biomarker for therapeutic response in Non-AFP-secreting hepatocellular carcinoma. BMC Cancer. 2025;25:199. doi:10.1186/s12885-025-13568-4 We aimed to discover how well PIVKA-II can predict treatment response in patients with non-AFP-secreting hepatocellular carcinoma (HCC) receiving systemic therapy. By measuring PIVKA-II levels and assessing imaging after 8-12 weeks of treatment, we found a connection between PIVKA-II levels, tumor size, and treatment outcomes. The study revealed a promising “50-50 rule” that can indicate prognosis based on PIVKA-II changes, making it a valuable marker for HCC treatment success. 7.5 Antitumour properties Most Useful Review 221 people found this helpful Vitamin K2 is vital for calcium absorption and blood clotting. It redirects calcium from the blood to bone tissue, which is crucial for bone and dental health. Notably, in 2006, its antitumour properties were discovered, showing benefits against certain cancers, including lung, pancreatic, bladder, and rectal. Ongoing studies continue to explore its potential.
Jarrow Formulas, MK-7, 90 mcg, 120 Softgels	7.6	7.9
9 PIVKA-II shows promise for HCC PIVKA-II as a surrogate biomarker for therapeutic response in Non-AFP-secreting hepatocellular carcinoma. Chen SC, Ho HL, Liu CA, Hung YP, Chiang NJ, et al. PIVKA-II as a surrogate biomarker for therapeutic response in Non-AFP-secreting hepatocellular carcinoma. BMC Cancer. 2025;25:199. doi:10.1186/s12885-025-13568-4 We aimed to discover how well PIVKA-II can predict treatment response in patients with non-AFP-secreting hepatocellular carcinoma (HCC) receiving systemic therapy. By measuring PIVKA-II levels and assessing imaging after 8-12 weeks of treatment, we found a connection between PIVKA-II levels, tumor size, and treatment outcomes. The study revealed a promising “50-50 rule” that can indicate prognosis based on PIVKA-II changes, making it a valuable marker for HCC treatment success. 7.5 Antitumor properties Most Useful Review 4 people found this helpful K2 MK7 assists in the normal absorption of calcium and the strengthening of bones, as well as supports the maintenance of cardiovascular and nervous systems. At doses of D3 exceeding 5000 IU, it is crucial to take vitamin K2 MK7. Some substances essential for our body can only be synthesised with menaquinone. Vitamin K2 is recognised for its benefits in various bodily systems: it promotes cardiovascular health by directing calcium from the bloodstream to bone tissue, regulating bone density and blood clotting. Research has revealed that vitamin K2 can slow down, or even halt, cancer cell activity, showing positive effects on lung, pancreatic, bladder, and rectal cancers.
NOW Foods, Vitamin K-2, 100 mcg, 100 Veg Capsules	7.6	7.9
9 PIVKA-II shows promise for HCC PIVKA-II as a surrogate biomarker for therapeutic response in Non-AFP-secreting hepatocellular carcinoma. Chen SC, Ho HL, Liu CA, Hung YP, Chiang NJ, et al. PIVKA-II as a surrogate biomarker for therapeutic response in Non-AFP-secreting hepatocellular carcinoma. BMC Cancer. 2025;25:199. doi:10.1186/s12885-025-13568-4 We aimed to discover how well PIVKA-II can predict treatment response in patients with non-AFP-secreting hepatocellular carcinoma (HCC) receiving systemic therapy. By measuring PIVKA-II levels and assessing imaging after 8-12 weeks of treatment, we found a connection between PIVKA-II levels, tumor size, and treatment outcomes. The study revealed a promising “50-50 rule” that can indicate prognosis based on PIVKA-II changes, making it a valuable marker for HCC treatment success. 7.5 Promotes cellular health Most Useful Review 8 people found this helpful One of the few products that is exclusively MK-4. While many emphasise the MK-7 form of Vitamin K2 for its calcium-enhancing qualities, I prefer MK-4 as it is found in the brain and regulates gene expression uniquely. It activates genes that maintain cell health while deactivating those that promote cancer. Animals convert other forms of Vitamin K to MK-4, but this process is inefficient and varies by genetics, making MK-4 supplementation potentially beneficial. However, some argue that MK-4 supplements are synthetic and may have low bioavailability.
Beta Glucan
NOW Foods, Beta-Glucans, with ImmunEnhancer, Extra Strength, 250 mg, 60 Veg Capsules	7.8	7.8
8 Hydrothermal yeast impacts breast cancer Hydrothermal treatment of yeast cell wall generates potent anti-proliferative agents targeting MCF7 breast cancer cells effectively even under culture conditions separated by a plastic wall. Kitagawa T. Hydrothermal treatment of yeast cell wall generates potent anti-proliferative agents targeting MCF7 breast cancer cells effectively even under culture conditions separated by a plastic wall. PLoS One. 2025;20:e0313379. doi:10.1371/journal.pone.0313379 We investigated the ability of a hydrothermally treated yeast cell wall to fight against MCF-7 breast cancer cells. This innovative method improved solubility and produced a potent anti-proliferative agent. The treatment significantly reduced cancer cell growth by nearly 59%, even when separated by a plastic barrier. This suggests that a diffusible factor in the treated yeast contributes to this anti-cancer effect, likely linked to reactive carbon species generated during treatment. Overall, our findings hint at a promising potential for this approach in cancer therapy development. 7.5 Effective support Most Useful Review 87 people found this helpful Helps me for a long time in the fight against cancer. I discovered this product through my doctor after a detailed immune analysis showed deficiencies. As I'm undergoing chemotherapy, I need to support my body. Since I began taking this in 2018, I’ve seen results: stomatitis and dermatophytosis have disappeared. Most importantly, there is some stability in my underlying disease (sarcoma). Last year, I paused the medication, and in three months, I noticed a negative trend. Ultimately, I've decided to continue this medication for my lifetime as I can clearly see the benefits!
N Acetyl Cysteine Nac
Doctor's Best, NAC Detox Regulators with Seleno Excell®, 60 Veggie Caps	8.2	7.4
9.5 Selenium drug shows selective toxicity Selenium Electrophilic Center Responsive to Biological Electron Donors for Efficient Chemotherapy. Qin X, Guo J, Li H, He H, Cai F, et al. Selenium Electrophilic Center Responsive to Biological Electron Donors for Efficient Chemotherapy. Adv Sci (Weinh). 2025. doi:10.1002/advs.202412062 We examined how a selenium-containing drug, known as RuSe, targets cancer cells while sparing normal cells. This innovative approach leverages the unique properties of selenium, specifically its electrophilic center, to create oxidative stress within cancer cells. By shuttling electrons from biological electron donors, the drug activates a sequence of events detrimental to cancer survival. The results were striking; we found that the rate of electron transfer at the selenium site is significantly higher in cancer cells compared to normal cells—1.81 times greater, to be precise. This selective action leads to a lethal effect, with the drug being 14.98 times more harmful to cancer cells than to their healthy counterparts. We observed that the generation of superoxide anions from this process causes DNA damage and triggers the p53 signaling pathway, which enhances the drug's effectiveness in killing cancer cells. Our findings offer an exciting new avenue for crafting chemotherapeutic agents that can be both efficient and less toxic. By exploiting the special properties of selenium, we open the door to more intelligent and targeted cancer therapies that could reduce side effects for patients. 10 Cancer prevention Most Useful Review 17 people found this helpful Great product! I had stage 4 cancer, and this supplement is essential for helping me stay cancer-free!
Life Extension, N-Acetyl-L-Cysteine, 600 mg, 60 Capsules	6.8	8.4
8 Rutecarpine shows anti-cancer promise Rutecarpine Suppresses Non-Small Cell Lung Cancer Progression Through Activating the STING Pathway and Elevating CD8+ T Cells. Jiang ZB, He QH, Kang LP, Jiang S, Liu JN, et al. Rutecarpine Suppresses Non-Small Cell Lung Cancer Progression Through Activating the STING Pathway and Elevating CD8+ T Cells. Chem Biol Drug Des. 2025;105:e70070. doi:10.1111/cbdd.70070 We explored the effect of rutecarpine, a natural compound from Chinese herbs, on non-small cell lung cancer (NSCLC) and how n-acetyl-l-cysteine (NAC) interacts with this treatment. Our study showed that rutecarpine can trigger cell death and reduce the growth of cancer cells, primarily by promoting the production of reactive oxygen species (ROS) that lead to mitochondrial dysfunction. Importantly, we observed that when cells were exposed to NAC, it was able to suppress this ROS production, suggesting that NAC might mitigate some of rutecarpine’s cancer-fighting effects. We also noted that rutecarpine activated the STING pathway and increased the levels of immune signals, which could boost the body's immune response against the tumor. However, while NAC plays a protective role by dampening excess ROS, it’s clear that rutecarpine’s ability to combat NSCLC is more pronounced when NAC is not present. In in vivo studies, rutecarpine not only slowed tumor growth significantly, but also elevated the presence of active CD8 T cells, enhancing antitumor immunity. This shows promise for rutecarpine as a potential treatment for lung cancer, albeit with a nuanced interaction with NAC that requires further exploration. 9 Glutathione production improved Most Useful Review I wholeheartedly recommend this modified form of cysteine. It significantly boosts glutathione levels in the body, which is critical in fighting cancer and preventing ageing. Acetylcysteine's detoxifying ability is notable, and its effectiveness is widely recognised in both preventive and curative cardiology practices.
Sports Fish Oil Omegas
Sports Research, Omega-3 Fish Oil, Triple Strength , 30 Softgels	7.6	7.9
9 Impact of Omega-3 on Cancer Novel inhibitory effect of Omega-3 fatty acids regulating pancreatic cancer progression. Garay MI, Mazo T, Ferrero V, Barotto NN, Lagares C, et al. Novel inhibitory effect of Omega-3 fatty acids regulating pancreatic cancer progression. Carcinogenesis. 2025;46. doi:10.1093/carcin/bgae081 We explored the effects of eicosapentaenoic acid, a type of omega-3 fatty acid, on pancreatic cancer using a specially designed mouse model that closely mimics human disease. This model allowed us to examine how adding omega-3 to the diet could impact cancer progression. Our findings revealed that a diet enriched with eicosapentaenoic acid led to a significant reduction in tumor size and metastasis to the lungs and liver. We also observed a trend toward improved survival rates in the mice that received this dietary intervention compared to those that did not. Interestingly, the treatment not only changed the fatty acid profile in the tumors but also influenced certain cellular processes. We noted an increase in apoptosis, or programmed cell death, without affecting how fast the cancer cells were growing. Additionally, there was a marked decrease in tumor fibrosis associated with lower levels of Sonic Hedgehog, a key player in pancreatic cancer development. Overall, our research suggests that eicosapentaenoic acid holds promise as a dietary intervention for cancer treatment, potentially opening new doors for incorporating nutritional strategies in managing pancreatic cancer. 9 Essential for family Most Useful Review Due to my family's struggles with cancer, I need to take high doses of fish oil, particularly those rich in EPA. Just one fish oil a day is manageable, especially for the elderly, and it is in an easily absorbed Tg form. I highly recommend it.
Astragalus
NOW Foods, Astragalus Extract, 500 mg, 90 Veg Capsules	7	8.5
7 Positive effects of herbal treatment The effect of a traditional Chinese prescription for a case of lung carcinoma. Kamei T, Kumano H, Iwata K, Nariai Y, Matsumoto T. The effect of a traditional Chinese prescription for a case of lung carcinoma. J Altern Complement Med. 2000;6:557. We examined the effectiveness of Ninjin Yoei To (NYT), a traditional herbal medicine that contains astragalus root among other ingredients, in treating lung cancer. Over a period of 7 weeks, an elderly patient received a daily dose of 15 grams of NYT. During the study, we observed notable changes in the patient's health. The levels of tumor markers, specifically CEA and CA19-9, decreased. Additionally, the patient’s symptoms improved significantly as her cough vanished and her appetite returned, indicating an enhancement in her overall well-being. While the study did not isolate the effects of astragalus root alone, the positive outcomes suggest that traditional herbal combinations, including this ingredient, may offer benefits for cancer patients. The assessments based on yin-yang and xu-shi diagnostic systems even indicated a shift in the patient’s health status. Although NYT is a multi-component herbal formula, we still see it enhancing quality of life for patients facing malignancies. Hence, incorporating such traditional remedies might be a valuable aspect of holistic care in cancer treatment. 9 Extra energy gained Most Useful Review 4 people found this helpful This Astragalus extract provides me with extra energy while undergoing cancer treatments.
Vitamins
Carlson, Baby's Super Daily® D3, 10 mcg (400 IU), 0.35 fl oz (10.3 ml)	7.3	8.2
5 Vitamin D's role in breast disease Levels of Serum 25-Hydroxy Vitamin D in Benign and Malignant Breast Disease Patients: An Observational Study. Soni D, Tiwari A, Kushwah PS, Dubey S, Khan S. Levels of Serum 25-Hydroxy Vitamin D in Benign and Malignant Breast Disease Patients: An Observational Study. Cureus. 2025;17:e78283. doi:10.7759/cureus.78283 We conducted an observational study to examine the levels of vitamin D in female patients with benign and malignant breast diseases. The research aimed to determine if there is a significant difference in vitamin D levels between those with non-cancerous conditions and those diagnosed with breast cancer. During the study, we analyzed adult female patients admitted to a surgical department. Importantly, we excluded those who had taken vitamin D supplements recently or who had prior vitamin D deficiencies. By measuring serum vitamin D levels through a specific testing method, we were able to gather meaningful data about their relationship to breast health. Our findings indicated a notable difference in average vitamin D levels when comparing the two groups. This suggests that inadequate vitamin D could be linked to an increased risk of developing breast cancer. Therefore, we explored the potential benefits of vitamin D supplementation as a preventive measure against breast cancer—though we acknowledge that larger and more controlled studies are essential to draw firm conclusions. At the same time, we recognize that vitamin D has effects beyond bone health, and it is crucial to consider these broader impacts when discussing its role in cancer risk. 7.5 Reduces inflammation Most Useful Review Vitamin D promotes the absorption of calcium and phosphorus, vital for bone growth. Beyond its structural role, it also protects against cancer cell growth, assists the immune system in fighting infections, and lessens inflammation. It is critical for the normal functioning of the neuromuscular, endocrine, and immune systems.
21st Century, Calcium Citrate + D3 Maximum, 75 Tablets	7.3	8
8 Vitamin D3 offers anti-cancer benefits Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Ezcurra-Hualde M, Zalba S, Bella Á, Arrizabalaga L, Risson A, et al. Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Front Immunol. 2025;16:1529007. doi:10.3389/fimmu.2025.1529007 We investigated the potential of vitamin D3, also known as cholecalciferol, in combating cancer while addressing concerns about its toxicity at higher doses. This study focused on enhancing the effectiveness of vitamin D3 through a clever method called liposomal encapsulation, which helps minimize side effects. We prepared liposomal vitamin D3 (VD-LP) and conducted various tests to understand its capabilities. We found that this encapsulated form not only maintained high efficiency but also demonstrated improved stability. Our analyses showed that VD-LP had strong effects against cancer cells from colorectal, breast, and prostate cancers. Remarkably, it affected gene expression in immune cells, boosting elements that help fight infections and support the body's defenses. Notably, VD-LP did a great job slowing tumor growth in mice and improved their survival rates without causing adverse effects like hypercalcemia, which is often a concern with regular vitamin D3 use. This evidence indicates that liposomal encapsulation of vitamin D3 could offer an effective cancer treatment strategy while minimizing unwanted side effects. We believe this may pave the way for further research and clinical applications, showcasing vitamin D3 as a valuable addition to cancer therapy. 7.5 Positive results noted Most Useful Review This calcium supplement has proven effective with a good combination of vitamin D3. I purchased it for a friend's parents dealing with cancer, relying on positive reviews from cancer patients' forums. The packaging is great and priced reasonably. There has already been noticeable improvement after taking it, so I highly recommend it!
Life Extension, Vitamins D and K with Sea-Iodine, 60 Capsules	7.5	7.7
8 Vitamin D3 offers anti-cancer benefits Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Ezcurra-Hualde M, Zalba S, Bella Á, Arrizabalaga L, Risson A, et al. Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Front Immunol. 2025;16:1529007. doi:10.3389/fimmu.2025.1529007 We investigated the potential of vitamin D3, also known as cholecalciferol, in combating cancer while addressing concerns about its toxicity at higher doses. This study focused on enhancing the effectiveness of vitamin D3 through a clever method called liposomal encapsulation, which helps minimize side effects. We prepared liposomal vitamin D3 (VD-LP) and conducted various tests to understand its capabilities. We found that this encapsulated form not only maintained high efficiency but also demonstrated improved stability. Our analyses showed that VD-LP had strong effects against cancer cells from colorectal, breast, and prostate cancers. Remarkably, it affected gene expression in immune cells, boosting elements that help fight infections and support the body's defenses. Notably, VD-LP did a great job slowing tumor growth in mice and improved their survival rates without causing adverse effects like hypercalcemia, which is often a concern with regular vitamin D3 use. This evidence indicates that liposomal encapsulation of vitamin D3 could offer an effective cancer treatment strategy while minimizing unwanted side effects. We believe this may pave the way for further research and clinical applications, showcasing vitamin D3 as a valuable addition to cancer therapy. 9 Supports immunity enhancement Most Useful Review This is one of the best manufacturers of vitamin D. It promotes muscle tone, increases immunity, supports thyroid function and normal blood clotting, and aids in restoring the protective sheaths around nerves. It also regulates blood pressure and heart rate while preventing cancer cell growth. I recommend taking it year-round at a dosage of 1000, ensuring sufficient levels in the body. Remember, vitamin D has a cumulative effect, so there's no fear of overdose when paired with vitamin K, which reduces liver strain.
ChildLife Essentials, Liquid Vitamin C, Natural Orange, 4 fl oz (118 ml)	N/A	8.2
9 Supports immune system Most Useful Review I ordered it for my child, who liked it. This product has good quality, natural ingredients, and a pleasant taste. Vitamin C supports the active immune system, has antiviral, antibacterial, and anti-inflammatory effects, and helps prevent the occurrence of cancer. It also aids in the synthesis of hormones and promotes iron absorption, which is beneficial for maintaining energy levels. 7.5 Strengthens immune system Most Useful Review My child has been using this vitamin C since her cancer diagnosis. Along with other supplements, this vitamin has kept her immune system strong.
Pancreatin
Nature's Way, Mega-Zyme, Systemic Enzymes, 100 Tablets	6.9	8.5
8 Pancreatin may prevent weight loss Placebo controlled trial of enteric coated pancreatin microsphere treatment in patients with unresectable cancer of the pancreatic head region. Bruno MJ, Haverkort EB, Tijssen GP, Tytgat GN, van Leeuwen DJ. Placebo controlled trial of enteric coated pancreatin microsphere treatment in patients with unresectable cancer of the pancreatic head region. Gut. 1998;42:92. We conducted a randomized double-blind trial to see if pancreatin could help prevent weight loss in patients with unresectable cancer of the pancreatic head region. Over eight weeks, 21 patients received either pancreatin or a placebo, alongside dietary counseling. Those on pancreatin gained weight, while placebo patients lost weight. The results showed a significant difference, suggesting that pancreatin may effectively counteract weight loss during this critical period. 9 Immune system support Most Useful Review 16 people found this helpful I took Mega-Zim instead of the German Wobenzym, and it has proven to be even better in terms of enzyme composition. I took 5 tablets four times a day for ten days. It played a crucial role in exposing cancer cells to my immune system, allowing it to fight effectively. I consumed Mega-Zim an hour before meals with warm water, specifically to enrich my blood with enzymes. The quality and results were excellent, and I highly recommend it.
Elderberry Sambucus
NOW Foods, Sambucus Zinc-C, 60 Lozenges	7.6	7.8
9 Vitamin C enhances immune response Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. He X, Wang Q, Cheng X, Wang W, Li Y, et al. Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. Cell. 2025. doi:10.1016/j.cell.2025.01.043 We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1. By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells. Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C. 9 Prostate cancer prevention Most Useful Review This product is very useful in preventing prostate cancer and provides general benefits to the body.
Nature's Way, Black Elderberry, 1,150 mg, 100 Vegan Capsules (575 mg per Capsule)	6.9	8.3
8 Elderberry protein's anticancer potential Recombinant pebulin protein, a type 2 ribosome-inactivating protein isolated from dwarf elder (Sambucus ebulus L.) shows anticancer and antifungal activities in vitro. Rezaei-Moshaei M, Dehestani A, Bandehagh A, Pakdin-Parizi A, Golkar M, et al. Recombinant pebulin protein, a type 2 ribosome-inactivating protein isolated from dwarf elder (Sambucus ebulus L.) shows anticancer and antifungal activities in vitro. Int J Biol Macromol. 2021;174:352. doi:10.1016/j.ijbiomac.2021.01.129 We focused on a newly identified protein called pebulin, derived from dwarf elder, and examined its potential anticancer effects. The protein was successfully produced in E. coli and purified for further testing. Our tests revealed that pebulin is not only capable of agglutinating red blood cells from all human blood types but also has significant inhibitory effects on cancer cell lines like MCF-7 and HT-29. This means that pebulin could slow down the growth of these cancer cells, a promising outcome we found particularly exciting. Additionally, we noted that pebulin demonstrated effectiveness against certain plant fungi, showcasing its versatile bioactivity. The study suggests that pebulin may offer a new avenue for cancer treatment, particularly considering its impact on both cancer cells and fungi. 9 Cancer fighter Most Useful Review Very excellent; it is regarded as a cancer fighter and an antioxidant.
Cat Claw
NOW Foods, Cat's Claw, 500 mg, 250 Veg Capsules	7.3	7.9
9 Cat's claw shows anti-cancer promise Treatment with Promotes Apoptosis in B16-BL6 Mouse Melanoma Cells and Inhibits the Growth of B16-BL6 Tumours. Zari A, Alfarteesh H, Buckner C, Lafrenie R. Treatment with Promotes Apoptosis in B16-BL6 Mouse Melanoma Cells and Inhibits the Growth of B16-BL6 Tumours. Molecules. 2021;26. doi:10.3390/molecules26041066 We explored the potential of cat's claw, a medicinal plant from Peru, as a treatment for cancer using B16-BL6 mouse melanoma cells. In controlled experiments, we treated these cancer cells with both ethanol and phosphate-buffered saline extracts of cat's claw. The results were promising, showing a remarkable reduction in cell growth—up to 80% less compared to untreated cells—and a notable increase in apoptosis, which is a form of programmed cell death essential for eliminating cancer cells. Our in vivo studies with C57/bl mice provided further insights. Mice treated with both ethanolic and aqueous extracts of cat's claw showed a substantial decrease in tumor weight by an average of 59% and a reduction in tumor size by about 40%. We also performed histochemical analysis, which revealed a significant drop in the Ki-67 marker—indicative of cell proliferation—in the tumors of treated mice. While there was a slight increase in TUNEL staining, it was not statistically significant. Additionally, we observed that cat's claw extracts reduced markers of angiogenesis and limited T cell infiltration into the tumors. Overall, our research indicates that cat's claw exhibits powerful anti-cancer properties, enlightening its potential as a complementary treatment in cancer therapy. 9 Supports healing process Most Useful Review 112 people found this helpful Cat's Claw is an effective detoxifier and is recommended for individuals recovering from chemotherapy and radiation therapy. It aids the immune system and exhibits antitumour activity against cancer. The plant also facilitates wound healing. I find it beneficial for both my son and me in our recovery.
Grape Seed Extract
NOW Foods, Grape Seed, Standardized Extract, 100 mg, 100 Veg Capsules	7	8.1
9 Vitamin C enhances immune response Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. He X, Wang Q, Cheng X, Wang W, Li Y, et al. Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response. Cell. 2025. doi:10.1016/j.cell.2025.01.043 We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1. By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells. Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C. 9 Vitality boost Most Useful Review 6 people found this helpful I drink it consistently. At the end of my cancer journey, I consulted a second opinion hospital and continue to take cancer research with a prescription from a long-time American university professor. I believe this has been beneficial as I strive to remain energetic despite being given a life expectancy of only three months.
Calcium Citrate
Solgar, Calcium Citrate with Vitamin D3, 240 Tablets	6.8	8.3
5 Vitamin D's role in breast disease Levels of Serum 25-Hydroxy Vitamin D in Benign and Malignant Breast Disease Patients: An Observational Study. Soni D, Tiwari A, Kushwah PS, Dubey S, Khan S. Levels of Serum 25-Hydroxy Vitamin D in Benign and Malignant Breast Disease Patients: An Observational Study. Cureus. 2025;17:e78283. doi:10.7759/cureus.78283 We conducted an observational study to examine the levels of vitamin D in female patients with benign and malignant breast diseases. The research aimed to determine if there is a significant difference in vitamin D levels between those with non-cancerous conditions and those diagnosed with breast cancer. During the study, we analyzed adult female patients admitted to a surgical department. Importantly, we excluded those who had taken vitamin D supplements recently or who had prior vitamin D deficiencies. By measuring serum vitamin D levels through a specific testing method, we were able to gather meaningful data about their relationship to breast health. Our findings indicated a notable difference in average vitamin D levels when comparing the two groups. This suggests that inadequate vitamin D could be linked to an increased risk of developing breast cancer. Therefore, we explored the potential benefits of vitamin D supplementation as a preventive measure against breast cancer—though we acknowledge that larger and more controlled studies are essential to draw firm conclusions. At the same time, we recognize that vitamin D has effects beyond bone health, and it is crucial to consider these broader impacts when discussing its role in cancer risk. 9 Breast cancer concern Most Useful Review 4 people found this helpful Wonderful product! Highly recommend it! The tablets are not as large as others claim. I typically take one or two tablets several times a day, but it's best to take two at night for better sleep. They are significantly smaller than the calcium pills I previously took, which is a huge plus! I will certainly purchase them again! It's also important to mention they are soy-free, which is crucial for me as I have had breast cancer.
MSM
Jarrow Formulas, Vegan MSM, 1,000 mg, 200 Veggie Capsules	6.3	8.7
7 MSM anal cancer treatment feasibility Piloting of a Screen‑Triage‑Treat Surgical Approach Model for Management of Anal Cancer in Liberia. Reynolds CW, Lieb W, Schecter A, Gaisa MM, McGill SK, et al. Piloting of a Screen‑Triage‑Treat Surgical Approach Model for Management of Anal Cancer in Liberia. Ann Glob Health. 2024;90:75. doi:10.5334/aogh.4576 We explored the challenges faced by men who have sex with men (MSM) regarding anal cancer treatment in Liberia. With limited access to screening and care for anal cancers, we aimed to investigate whether a screen-triage-treat approach could effectively help identify and manage anal high-grade squamous intraepithelial lesions (aHSIL) within this vulnerable population. In our study, we collaborated with local organizations to gather data from MSM and transgender individuals. Participants were recruited and engaged in self-swabbing to test for high-risk human papillomavirus (HPV), alongside HIV testing. Those who tested positive for aHSIL were offered further evaluation and treatment using high-resolution anoscopy and infrared coagulation. Among 110 participants, a significant number turned out to be living with HIV, and nearly half tested positive for high-risk HPV. This indicates a notable health concern. While 68% of those who tested positive opted for further procedures, we found that this model effectively presented a potential solution for identifying anal cancer risks and can work in a low-resource environment. Overall, our findings suggest that implementing a screen-triage-treat model shows promise for reducing anal cancer incidence among MSM in Liberia. This approach, previously successful in cervical cancer management, might become a crucial tool in cancer prevention strategies for similar low- and middle-income countries. 9 Improves recovery and health Most Useful Review 129 people found this helpful Methylsulfonylmethane (MSM) is excellent for my ballet training as it supports my joints and aids recovery. The effects are tangible; it's best taken with silicon supplements. MSM not only helps with joint pain and cholesterol levels but also possesses anti-cancer properties, boosts immunity, detoxifies the liver, promotes normal blood levels, and enhances brain function.
Doctor's Best, MSM with OptiMSM®, 3,000 mg, 360 Capsules (1,000 mg per Capsule)	6.3	8.6
7 MSM anal cancer treatment feasibility Piloting of a Screen‑Triage‑Treat Surgical Approach Model for Management of Anal Cancer in Liberia. Reynolds CW, Lieb W, Schecter A, Gaisa MM, McGill SK, et al. Piloting of a Screen‑Triage‑Treat Surgical Approach Model for Management of Anal Cancer in Liberia. Ann Glob Health. 2024;90:75. doi:10.5334/aogh.4576 We explored the challenges faced by men who have sex with men (MSM) regarding anal cancer treatment in Liberia. With limited access to screening and care for anal cancers, we aimed to investigate whether a screen-triage-treat approach could effectively help identify and manage anal high-grade squamous intraepithelial lesions (aHSIL) within this vulnerable population. In our study, we collaborated with local organizations to gather data from MSM and transgender individuals. Participants were recruited and engaged in self-swabbing to test for high-risk human papillomavirus (HPV), alongside HIV testing. Those who tested positive for aHSIL were offered further evaluation and treatment using high-resolution anoscopy and infrared coagulation. Among 110 participants, a significant number turned out to be living with HIV, and nearly half tested positive for high-risk HPV. This indicates a notable health concern. While 68% of those who tested positive opted for further procedures, we found that this model effectively presented a potential solution for identifying anal cancer risks and can work in a low-resource environment. Overall, our findings suggest that implementing a screen-triage-treat model shows promise for reducing anal cancer incidence among MSM in Liberia. This approach, previously successful in cervical cancer management, might become a crucial tool in cancer prevention strategies for similar low- and middle-income countries. 9 Accelerates hair growth Most Useful Review 6 people found this helpful I absolutely love this product! Since using MSM, my hair and nails have been growing remarkably quickly. I also believe it is excellent for combatting cancer.
Glucosamine Chondroitin Formulas
Doctor's Best, Glucosamine Chondroitin MSM with OptiMSM®, 240 Capsules	6.3	8.4
7 MSM anal cancer treatment feasibility Piloting of a Screen‑Triage‑Treat Surgical Approach Model for Management of Anal Cancer in Liberia. Reynolds CW, Lieb W, Schecter A, Gaisa MM, McGill SK, et al. Piloting of a Screen‑Triage‑Treat Surgical Approach Model for Management of Anal Cancer in Liberia. Ann Glob Health. 2024;90:75. doi:10.5334/aogh.4576 We explored the challenges faced by men who have sex with men (MSM) regarding anal cancer treatment in Liberia. With limited access to screening and care for anal cancers, we aimed to investigate whether a screen-triage-treat approach could effectively help identify and manage anal high-grade squamous intraepithelial lesions (aHSIL) within this vulnerable population. In our study, we collaborated with local organizations to gather data from MSM and transgender individuals. Participants were recruited and engaged in self-swabbing to test for high-risk human papillomavirus (HPV), alongside HIV testing. Those who tested positive for aHSIL were offered further evaluation and treatment using high-resolution anoscopy and infrared coagulation. Among 110 participants, a significant number turned out to be living with HIV, and nearly half tested positive for high-risk HPV. This indicates a notable health concern. While 68% of those who tested positive opted for further procedures, we found that this model effectively presented a potential solution for identifying anal cancer risks and can work in a low-resource environment. Overall, our findings suggest that implementing a screen-triage-treat model shows promise for reducing anal cancer incidence among MSM in Liberia. This approach, previously successful in cervical cancer management, might become a crucial tool in cancer prevention strategies for similar low- and middle-income countries. 9 Reduces cancer risk Most Useful Review Glucosamine sulfate is a simple sugar that prevents glucose oxidation. The dosage is critical; for an 80 kg person, 2000 mg daily can lead to heart issues and reduced lifespan if taken young. However, studies reveal that for those over 50, glucosamine is linked to a 41% lower risk of mortality from respiratory infections and a significant reduction in lung and colorectal cancer risks. Though I don’t take it as I’m still young, it provides my grandmother with crucial relief for her knees and potentially extends her life.
Turmeric Curcumin
Jarrow Formulas, Curcumin 95, Turmeric Extract, 500 mg, 120 Veggie Capsules	N/A	8.7
10 Achieved remission Most Useful Review 103 people found this helpful I have been taking 2 gms (4 capsules) of curcumin daily since my stage 4 breast cancer diagnosis a year ago. Remarkably, I went into remission within three months, and there has been no evidence of cancer for the past eight months. 9 Cancer remission Most Useful Review 23 people found this helpful After taking curcumin for about four months, I noticed a significant boost in my immune system. I also recommended it to my aunt, who had stage 4 lymphoma, and I am thrilled to share that her cancer has gone into remission after about a month on it.
NOW Foods, Turmeric Curcumin Gels, 475 mg, 120 Softgels	N/A	8.4
9 Strong anti-cancer effects Most Useful Review 2 people found this helpful Excellent remedy! Research has confirmed that turmeric possesses strong anti-inflammatory, antiviral, analgesic, antimicrobial, and anti-cancer effects. It is one of the most studied antioxidant medicinal plants globally. My entire family drinks it, and I encourage everyone to try it. 7.5 Effective against inflammation Most Useful Review 2 people found this helpful Good product. It aids in combating the body's inflammatory process. I had cancer and, after all the treatments, I began taking one capsule daily for four years. So far, so good. A tip: always take it on a full stomach, and be cautious with the daily dosage. I settled on one capsule per day, which makes me feel well.
Collagen Supplements
NOW Foods, UC-II® Joint Health with Undenatured Type II Collagen, 120 Capsules	N/A	8.5
9 Relieved discomfort Most Useful Review Praise! Following my treatment for breast cancer, I took the anti-hormone drug Sodium Dipyridoxine, which caused severe pain in my hand and foot joints. Thankfully, UCII has improved my joint health and relieved the discomfort significantly. I'm a fan of Now Foods; it's safe and effective, and I will definitely continue to repurchase it. 9 Significant improvement Most Useful Review My first choice for joint care! Over the past year, I increased my exercise to combat cancer, resulting in hip and knee joint pain. Taking one UCII pill every morning and evening has been transformative. After two months, the pain has vanished completely. My wife encourages me to continue using it, and I highly recommend it without reservation.
Multivitamins
NOW Foods, Super Antioxidants, 120 Veg Capsules	N/A	8.5
9 Skin cancer prevention Most Useful Review 2 people found this helpful My GP, who practices integrative medicine, recommended superantioxidants years ago for my skin cancer issues. After consistently taking one a day, I enjoyed a seven-year period without basal cell cancers. However, after neglecting them, I developed one more BBC and a melanoma, which prompted me to resume regular use. I plan to take them forever, as my sun protection routine remained unchanged during this time. 9 Prevents cancer spread Most Useful Review 12 people found this helpful Given the current situation of poor nutrition and the prevalence of inorganic meat and dairy products leading to the global rise in cancer, I highly recommend incorporating antioxidants into your daily diet.
NOW Foods, EVE, Superior Women's Multi, 180 Softgels	N/A	8.4
9 Effective prevention Most Useful Review This vitamin complex is a real godsend! Compared to Russian pharmacy brands, the potency of each microelement and vitamin is significantly greater, offering a more effective impact on the body. The dosage is perfect for an adult woman. I particularly valued the high selenium content, which is excellent for cancer prevention. I highly recommend these vitamins to my relatives and friends. 7.5 Enhanced health Most Useful Review I purchased this for my mother, who is a cancer patient. I believe these vitamins have enhanced and improved her health.
Amazing Grass, Organic Wheat Grass Powder, 1.76 lb (800 g)	N/A	8.4
7.5 Nutritional recovery boost Most Useful Review 4 people found this helpful This health drink is nutritious and not just tasty. I typically take it on an empty stomach, mixed with honey, and sometimes add Super Greenfood for an extra boost. I know individuals who have successfully recovered from cancer through a disciplined lifestyle that includes consuming freshly juiced organic wheatgrass daily. I prefer this wheatgrass powder drink as an alternative to juicing, though I'm unsure if it matches the nutritional quality. However, it’s certainly better than not consuming it at all. 9 Recommended for survivors Most Useful Review 3 people found this helpful Amazing Grass products offer a fantastic way to incorporate greens into my diet. I blend it in smoothies with blueberries, protein powder, and orange juice. As a cancer survivor, wheatgrass is highly regarded, and I believe it plays a crucial role in my health.
NOW Foods, B-50, 100 Veg Capsules	N/A	8.2
7.5 Helps during treatment Most Useful Review My mother uses this for her therapy and finds it helpful, particularly as she experiences fatigue during chemotherapy and radiotherapy. Cancer patients undergoing these treatments are susceptible to oral ulcers, and I've heard that B vitamins can be beneficial in alleviating some of these issues! 7.5 Prevents various cancers Most Useful Review The B vitamin group is vital for various biochemical functions such as metabolism and immunity. These vitamins help prevent liver cancer, lung cancer, and gastric cancer. They also act as natural anti-stress agents to support the nervous system and promote emotional balance.
American Health, Chewable Super Papaya Enzyme Plus, 360 Tablets	N/A	8.2
8 Benefits digestion, cancer Most Useful Review 2 people found this helpful A natural and excellent product, with a very appropriate and abundant quantity. Papaya offers great benefits for digestion, fighting cancer, infections, and ulcers. After placing my trust in God Almighty, I found this product to be particularly special. I wish everyone could benefit from it, and may you all remain well. 7.5 Supports cancer patients Most Useful Review Chewable papaya enzyme is a great product, very easy to take with a pleasant taste. I understand it is beneficial for cancer patients.
NOW Foods, Super Omega 3-6-9, 1,200 mg, 90 Softgels	N/A	8.1
7.5 Dietary support Most Useful Review 8 people found this helpful Unsaturated fatty acids are vital as they can't be made by the body and must come from food or supplements. Omega 3, 6, and 9 positively impact several conditions, including cancer. They support cholesterol metabolism, reduce obesity, and alleviate inflammation, which can help with symptoms tied to rheumatoid arthritis and cancer. 7.5 Beneficial for cancer Most Useful Review 92 people found this helpful Omega 3, 6, and 9 fatty acids significantly aid in various health issues. They support managing diabetes and allergies, regulate cholesterol metabolism, and have an anti-inflammatory effect, which can alleviate symptoms associated with cancer. Additionally, they enhance mood, concentration, and memory, and help in maintaining cell membrane integrity.
NOW Foods, ADAM, Superior Men's Multi, 90 Softgels	N/A	8.1
9 Aids during chemotherapy Most Useful Review I purchased this for my father, who is undergoing radiation therapy for cancer. It was vital to find a capsule with all the ingredients he required. At 70, he has found it excellent quality with an immediate positive effect. 9 Strengthens immune system Most Useful Review This product supercharges the immune system like a cancer rocket, providing unmatched energy. I highly recommend it.
Oregano Oil Supplements
North American Herb & Spice, Oreganol, Oil of Wild Oregano, 1 fl oz (30 ml)	N/A	8.4
9 Effective treatment Most Useful Review 18 people found this helpful I have been battling basal cell cancer and tried everything, but oregano oil is the only treatment that worked for me. I applied it twice daily and took two drops under my tongue each time. It's remarkable. Thank you! 7.5 Immune support Most Useful Review 4 people found this helpful I have cancer, and I discovered through a holistic doctor that wild oregano oil aids breast cancer patients. It keeps my immunity strong, especially when travelling. I managed to avoid illness, and it also helped my gums heal after dental work, without harming my gut flora. Its potent quality, particularly the Carvacrol concentration, is impressive.
Resveratrol
NOW Foods, Resveratrol, 200 mg, 120 Veg Capsules	N/A	8.4
9 Inflammation relief Most Useful Review 108 people found this helpful Resveratrol is an excellent, tested product that aids in preventing cancer and relieving inflammation. After suffering from increased leukocyte levels for years, I took Resveratrol for four months, and subsequent tests showed normal results. Now, I take it twice a year for prevention. 9 Cancer therapy Most Useful Review 1 people found this helpful Resveratrol is a well-studied natural compound with antioxidant properties. It is known to be anti-cancer and serves as a therapeutic agent.
Coconut Supplements
Jarrow Formulas, Extra Virgin Coconut Oil , 1,000 mg, 120 Softgels	N/A	8.4
9 Cancer risk reduction Most Useful Review Coconut oil is excellent for maintaining healthy fat levels, lowering the risks of atherosclerosis, cardiovascular disease, and even cancer. After consistent intake of 2-3 capsules daily, I noticed my hair shines, and my skin is well-nourished and moisturised. 7.5 Cancer treatment innovator Most Useful Review 1 people found this helpful Beating cancer! I utilise these tablets and prepare food using quality fats like olive, MCT, coconut, and hemp oil while adhering to "THE KETO WAY" to maintain my state of ketosis.
D Mannose
NOW Foods, D-Mannose, 500 mg, 120 Veg Capsules	N/A	8.4
10 Reduced UTIs significantly Most Useful Review 4 people found this helpful After severe surgical treatment for cancer, I was plagued by UTIs requiring antibiotics monthly for over three years, leaving my gut flora depleted. I tried numerous remedies until discovering D-Mannose. My surgeon approves, stating there's little more he can offer. I've almost completely eliminated UTIs, and taking two 500mg capsules at night has reduced them by at least 95%. This product has been a true blessing for me. 9 Helps stage IV cancer Most Useful Review 2 people found this helpful I am taking this for Stage IV breast cancer alongside D-Mannose, which my integrative doctor says targets cancer cells. Since it has spread to my brain, bones, liver, pericardium, and lungs, I'm willing to try anything. After finishing two bottles, I am starting to feel better.
Acetyl L Carnitine
NOW Foods, Acetyl-L-Carnitine, 500 mg, 200 Veg Capsules	N/A	8.3
9 Beat cancer effectively Most Useful Review I have been taking this supplement for years, and I swear by it. I also overcame stage 4 cancer. 7.5 Effective against cancer Most Useful Review I purchased Accel L Carnitine after learning it could be effective against my cancer. It has worked well without side effects as long as I take it in moderation.
Melatonin
NOW Foods, Extra Strength Melatonin, 10 mg, 100 Veg Capsules	N/A	8.3
9 Apoptosis enhancement Most Useful Review I take it for cancer purposes as numerous studies show high dosages (up to 160mg) significantly aid apoptosis. It's essential to increase the dosage gradually and consult your doctor before taking higher amounts. No side effects were reported at those levels, but it's better to be cautious. 9 Immune system support Most Useful Review Excellent! Melatonin supports the immune system and inhibits breast cancer development. It helps me sleep at night.
Natrol, Melatonin, Fast Dissolve, Maximum Strength, Citrus, 10 mg, 100 Tablets	N/A	8.1
9 Improved survival rate Most Useful Review The survival rate for those with mammary cancer who take melatonin daily is higher. I have been taking it daily for two years now. I have stage 4 cancer and am still alive.
Natrol, Melatonin, 5 mg, 60 Tablets	N/A	8
9 Safe for cancer recovery Most Useful Review I’ve been taking melatonin for years without fail, especially recommended after my breast cancer 20 years ago. It ensures I have a good night’s sleep and is safe without causing addiction. 9 Immune system support Most Useful Review I purchased this for my mother, who has cancer and was struggling to sleep. After starting the melatonin, she reported much better sleep. I plan to buy some for myself next!
Ginkgo Biloba
NOW Foods, Ginkgo Biloba, Double Strength, 120 mg, 200 Veg Capsules	N/A	8.3
9 Cell damage repair Most Useful Review 2 people found this helpful The benefits of Ginkgo biloba are remarkable; it alleviates depression, tension, and anxiety, especially for the elderly. It enhances blood circulation, particularly to the brain, and strengthens memory. Ginkgo works to prevent Alzheimer's disease by preserving nerve cells and stimulating blood flow, which boosts memory function. Moreover, it contains antioxidants that help prevent cancer and repair cell damage, significantly improving overall health. 9 Weight loss aid Most Useful Review מצוין! It's great for weight loss and also effective against cancer.
Doctor's Best, Extra Strength Ginkgo, 120 mg, 360 Veggie Caps	N/A	7.7
7.5 Reduces cancer spread Most Useful Review 1 people found this helpful Ginkgo extract promotes blood vessel expansion, lowers blood pressure, and reduces stroke risk. It decreases thrombosis risk, lowers cholesterol, and prevents age-related brain changes. The extract inhibits cancer metastasis while improving brain function and memory, essential for large city dwellers. I am purchasing it for the first time and anticipate positive results from its benefits. The packaging is attractive and should last long enough for thorough evaluation. 7.5 Encourages vascular health Most Useful Review 1 people found this helpful Ginkgo extract is recognised for stimulating blood vessel expansion and reducing blood pressure and stroke risks. It lowers the chances of thrombosis and cholesterol levels while preventing age-related brain changes. The extract also suppresses cancer metastases. With long-term use, it can enhance glucose absorption and coordination, combats sleep disorders, and stimulates mental activity, improving memory in older adults. It is beneficial for a wide range of age-related health issues and cognitive impairments.
Cranberry
Nature's Way, Cranberry Fruit, 930 mg, 180 Vegan Capsules (465 mg Per Capsule)	N/A	8.2
7.5 Cranberry cancer prevention Most Useful Review 1 people found this helpful Cranberry is wonderful for combating diseases linked to urinary tract infections and plays a significant role in preventing cardiovascular diseases, ageing, and cancer. Furthermore, it helps maintain the balance of intestinal flora and boosts immune defences against infection. 7.5 Cranberry benefits cancer Most Useful Review 1 people found this helpful The benefits of cranberry are numerous: it enhances immunity, addresses urinary tract issues, and prevents gastric problems including cancer. However, those with gastroesophageal reflux should avoid it. Cranberry can also support heart health, lower blood pressure, and reduce cholesterol. It may interact with certain medications, so consulting a doctor before consuming is advisable.
Lutein
NOW Foods, Lutein, 10 mg, 120 Softgels	N/A	8.2
7.5 Cancer prevention benefits Most Useful Review Lutein aids in preventing diabetic retinopathy, dry eye syndrome, and others. It additionally contributes to cancer prevention, particularly breast and lung cancer, while reducing the risk of coronary heart disease and enhancing the immune system. 9 Good anti-cancer activity Most Useful Review 1 people found this helpful I look forward to the positive effects of lutein and other ingredients. I bought an excellent product for my mother that has shown promising anti-cancer activity.
NOW Foods, Double Strength Lutein, 20 mg, 90 Veg Capsules	N/A	8
7.5 Vision and cancer Most Useful Review Among those over 65, macular degeneration is a leading cause of blindness. Clinical evidence confirms that lutein can significantly improve vision for patients with age-related macular disease. This carotenoid plays a crucial role in enhancing lens antioxidant capacity, potentially delaying cataract onset. It also protects retinal capillaries and maintains blood circulation, improving overall eyesight. Furthermore, lutein may aid in reducing the risk of various cancers, including breast and lung cancers, while boosting skin's anti-ultraviolet function and immune response. 7.5 Cancer prevention focus Most Useful Review Lutein is regarded as an important supplement in preventing age-related diseases, including cancer. Integrating this nutrient can support overall health and potentially mitigate cancer risks in older adults.
Doctor's Best, Lutein from OptiLut, 20 mg, 120 Veggie Caps (10 mg per Capsule)	N/A	8
9 Cancer management Most Useful Review 12 people found this helpful Since starting on OptiRoute Lutein, I have experienced a significant change, particularly regarding my long-standing battle with Anguard Cancer. For 19 years, I faced numerous challenges, but taking Optimus Lutein seemed to provide a sense of improvement in my overall condition. 9 Colon cancer findings Most Useful Review 4 people found this helpful Since I started taking it for my eyes, I've noticed a significant improvement. Research from the American Cancer Society indicated that individuals consuming high-lutein diets—found in vegetables like broccoli and spinach—have reported fewer cases of colon cancer. This connection reassures me of the supplement's potential benefits beyond ocular health.
Other
Nature's Way, Organic MCT Oil, 16 fl oz (480 ml)	N/A	8.2
9 Smooth morning flow Most Useful Review I take MCT oil in my butter coffee daily and have started consuming it at night to generate ketone bodies while I sleep, which I believe aids in cancer prevention. I've also enjoyed it with butter tea an hour before bedtime. The benefit of evening consumption has made my mornings easier, leading me to establish a routine of taking it both in the morning and at night. I’m pleased with the large bottle I purchased, ensuring ample supply for my needs. 7.5 Efficient energy use Most Useful Review I incorporate MCT oil into the butter coffee I have each morning. As it is tasteless and odourless, it blends seamlessly into my routine. MCT oil produces ketone bodies, which are anticipated to promote cell repair and offer cancer-suppressing benefits. Moreover, these ketone bodies assist in reducing body fat efficiently while providing energy.
NOW Foods, Super Primrose, 1,300 mg, 120 Softgels	N/A	8.1
7.5 Pain relief achieved Most Useful Review 10 people found this helpful I purchased evening primrose oil due to painful PMS symptoms, specifically breast tenderness before menstruation. After beginning to take one capsule daily, my symptoms vanished before my next cycle! I take it together with fat and omega 3 to enhance absorption. I'm delighted that my breast pain has subsided as mastopathy heightens the risk of breast cancer. The capsules are quite large but smooth, and I appreciate the proper dosage. 8 Blocks cancer development Most Useful Review 5 people found this helpful Evening primrose oil contains 1300 mg in one capsule and is excellent for normalising hormonal balance, alleviating PMS and menopause symptoms, and aiding in the prevention and treatment of conditions like fibrocystic mastopathy, ovarian dysfunction, endometriosis, and breast cancer. It helps prevent blood clots, reduces diabetes risk, and normalises blood pressure. The oil promotes skin elasticity, rapid wound healing, and has antibacterial and antifungal properties. Furthermore, it provides an antioxidant effect on body cells, blocking the development of cancer cells whilst improving nervous system function, sleep quality, and reducing irritability, ultimately slowing the ageing process.
NOW Foods, Mega D-3 & MK-7, 5,000 IU / 180 mcg, 60 Capsules	N/A	8
9 Boosted D3 levels Most Useful Review 3 people found this helpful This complex of vitamin D3 and MK-7 provides the right balanced dose. A deficiency can lead to osteoporosis and a 70% higher cancer risk. My vitamin D3 level increased from 10 to 67 units in two months. I can't recommend it enough. 9 Fights cancer risks Most Useful Review 1 people found this helpful This vitamin D3 and MK-7 complex provides a balanced dose. A lack of vitamin D can result in osteoporosis and increase cancer risk. My vitamin D levels rose significantly in just two months. Highly recommend.
NOW Foods, Turmeric & Bromelain, 90 Veg Capsules	N/A	8
7.5 Reduces cancer risk Most Useful Review 14 people found this helpful Organic turmeric is the secret behind the exceptional longevity in Okinawa Island, known for its high number of long-livers. With average life expectancies of 88 for men and 92 for women, it’s believed that regular turmeric consumption significantly lowers the risks of cancer, heart attacks, and strokes. From the first doses, you will feel invigorated and experience an extraordinary boost of energy. 7.5 Aids cancer prevention Most Useful Review This is a beneficial product that I give to my mother, who has a medical history. It is advisable to take it several times a year to combat cancer, treat cystitis, and generally bolster the immune system. Her cystitis has remained in remission for a year, and she also takes d-mannose.
Jarrow Formulas, Evening Primrose, 1,300 mg, 60 Softgels	N/A	7.8
7.5 Hormonal regulation benefits Most Useful Review 3 people found this helpful Evening primrose oil is rich in polyunsaturated fatty acids, especially gamma-linolenic acid (GLA), the key component. GLA's rarity emphasizes EPO's value. This oil boasts numerous beneficial properties: it helps normalise hormonal balance and alleviates symptoms of PMS and menopause while being effective against conditions like fibrocystic breast disease, ovarian dysfunction, endometriosis, and breast cancer. Additionally, it aids in preventing cardiovascular diseases and enhancing the condition of skin suffering from dryness or eczema. My mother has noticed a significant improvement in her menopause symptoms after two months of use, prompting me to repurchase. 9 Positively effects hormones Most Useful Review Excellent! 🌼 Evening primrose oil is an essential supplement for women's health, particularly during hormonal disruptions such as PMS and menopause. It plays a significant role in breast cancer prevention, alleviates symptoms related to hormonal imbalances, and supports overall skin and hair health. Each capsule taken can enhance well-being during challenging hormonal phases.
NOW Foods, Turmeric Curcumin Phytosome With Meriva, 500 mg, 60 Veg Capsules	N/A	7.8
9 Highly effective anti-inflammatory Most Useful Review 5 people found this helpful I was sceptical about its anti-inflammatory properties, but I tried it and I’m not disappointed! This turmeric supplement not only reduces inflammation but also boosts immunity, aids in wound healing, and has anti-cancer effects. I only take it when I feel unwell, and one capsule in the morning and evening alleviates my symptoms. I feel much better now! 9 Excellent cancer supplement Most Useful Review 1 people found this helpful My Natural Health Physician highlights curcumin’s power as an anti-inflammatory, addressing inflammation—the root cause of many diseases, including cancer. Studies show that curcumin can lower oxidative stress, linked to cancer progression. At 68, my husband and I find curcumin is vital for our health, offering substantial benefits, especially for combating cancer.
Garden of Life, Organics, Extra Strength Turmeric, Inflammatory Response, 60 Vegan Tablets	N/A	7.5
9 High dosage benefits Most Useful Review 2 people found this helpful Excellent! This is an exceptional curcumin formula with a high dosage and strong anti-inflammatory effect. It’s a highly desirable supplement for everyone as it offers anti-cancer properties, immuno-strengthening benefits, and choleretic effects. 7.5 Blocks cancer cells Most Useful Review 3 people found this helpful Turmeric contains essential oils and curcumin (a yellow pigment), being rich in nutrients like phosphorus, iron, and vitamins. It cleanses the body of toxins with antioxidants that eliminate free radicals. Studies suggest turmeric may aid against Alzheimer's, reduce arthritis swelling, and block cancer cell growth, including breast cancer.
Fiber
Citrucel, Methylcellulose Fiber Therapy for Irregularity, 180 Fiber Caplets	N/A	8.1
7.5 Anti-cancer effects Most Useful Review 228 people found this helpful Curcumin is a remarkable dietary supplement and offers numerous health benefits, including anti-cancer properties. It is known for its anti-inflammatory and antioxidant effects, and studies suggest it may alleviate osteoarthritis and rheumatoid arthritis symptoms. Curcumin has been associated with improvements in cardiovascular health, mood, and memory. Additionally, taking it with phospholipids and piperine enhances its bioavailability, making it highly effective. I highly recommend it for anyone looking to boost their health and well-being. 9 Strengthens immunity Most Useful Review 19 people found this helpful Garlic is excellent for the gut, enhancing enzyme secretion and digestion, while strengthening the immune system and improving cardiovascular health. It lowers cholesterol, aids high blood pressure, and reduces cancer risks. I firmly believe in garlic’s healing properties.
Bromelain
Doctor's Best, High Potency Bromelain, 500 mg, 90 Veggie Caps	N/A	8.1
9 Enzyme therapy helps Most Useful Review 8 people found this helpful I take the Shirochan Cancer Protocol as part of my systemic proteolytic enzymes, along with pancreatin, nattokinase, and serrapeptase, on an empty stomach. Enzyme therapy is crucial for cancer healing as it breaks down fibrin, which covers cancer cells, allowing our immune system to target them. It also mitigates chemotherapy side effects and is safe as it contains just enzymes. Your support in my natural cancer healing journey is greatly appreciated. Thank you! 9 Incredible for cancer Most Useful Review This product is incredibly effective for anyone battling cancer and is also beneficial against arthritis.
Astaxanthin
NOW Foods, Astaxanthin, 4 mg, 90 Softgels	N/A	8
7.5 Supports recovery post-surgery Most Useful Review I have been consistently taking astaxanthin after my cancer surgery, recommended by my doctor for its benefits. It has been two years since my operation, and I'm currently under regular observation, yet I feel healthy. Astaxanthin supplements are hard to find in stores, and it’s difficult to get enough from food, making this supplement very helpful for my recovery.
Grapeseed
NOW Foods, Solutions, Grapeseed Oil, 16 fl oz (473 ml)	N/A	8
7.5 Aids in cancer prevention Most Useful Review Grape seed oil offers several medical benefits, prominently contributing to cancer prevention. It also helps reduce diabetes severity and aids in weight management. Furthermore, it promotes overall heart and kidney health.
Barley Grass
Green Foods, Green Magma®, Barley Grass Juice Powder, 10.6 oz (300 g)	N/A	7.6
9 Improved health Most Useful Review 2 people found this helpful You are the best! Thank you for your products! They have greatly assisted my mum with her cancer! She is now in good health. 8 Health care effects Most Useful Review 1 people found this helpful Barley seedling powder is abundant in chlorophyll, antioxidant enzymes, and various nutrients. Medical research confirms its health benefits, particularly in anti-cancer effects, liver protection, and enhancing cell vitality. Consequently, it holds a significant role in health foods. Research shows chlorophyll effectively reduces carcinogenic toxicity more than vitamin C, vitamin E, or beta-carotene.