We dove into the connection between omega-3 fatty acids and stroke risks by analyzing data from 29 global cohorts, involving over 183,000 participants.
Our findings revealed that higher levels of omega-3s, particularly eicosapentaenoic acid and docosahexaenoic acid, are linked to a reduced risk of total and ischemic strokes. Specifically, those with the highest omega-3 levels experienced a 17% lower incidence of total stroke and an 18% reduced risk of ischemic stroke.
However, it's important to note that omega-3 levels showed no impact on hemorrhagic stroke risk.
Read More
9
DHA reduces stroke damage in mice
Docosahexaenoic acid protects against ischemic stroke in diabetic mice by inhibiting inflammatory responses and apoptosis.
We investigated the impact of docosahexaenoic acid (DHA) on stroke in diabetic mice. Our findings indicate that DHA significantly reduced brain damage and improved neurological functions.
The treatment not only decreased the inflammatory response but also lowered cell death within the brain. We noted remarkable changes in gene expression, suggesting that DHA promotes a protective environment in the brain after a stroke.
Overall, this research highlights DHA's potential as a therapeutic agent for stroke management in diabetic patients.
Read More
9
DHA promotes brain recovery post-stroke
Docosahexaenoic acid promotes M2 microglia phenotype via activating PPARγ-mediated ERK/AKT pathway against cerebral ischemia-reperfusion injury.
We investigated the effects of docosahexaenoic acid (DHA), an omega-3 fatty acid, on brain recovery after stroke due to ischemia-reperfusion injuries. In a study involving rats, we discovered that DHA significantly reduced brain damage by shifting microglia from a harmful pro-inflammatory state to a protective anti-inflammatory one.
By promoting M2 microglia and modulating specific signaling pathways, DHA helped in reducing inflammation and supported healing. However, using a PPARγ antagonist inhibited these helpful effects, pointing to the importance of this pathway in DHA’s neuroprotective role.
Read More
Most Useful Reviews
9
Cleanses artery walls
1 people found this helpful
Posh Omega helps reduce "bad" cholesterol, cleansing arteriole walls and lowering blood pressure. This leads to healthier blood viscosity and arterial elasticity, hence protecting against atherosclerosis, coronary heart disease, stroke, and myocardial infarction. My husband and I have been using it for three months, and the benefits are palpable.
Read More
9
Prevents stroke occurrence
Omega-3, an essential fatty acid found in fish oil, is crucial for numerous bodily functions. Due to insufficient dietary intake, supplements are vital. Fish oil enhances blood circulation, prevents arterial hypertension, and supports heart health, reducing the risk of arrhythmia, atherosclerosis, coronary heart disease, myocardial infarction, and stroke. It also aids nerve cell function and can positively affect mood, potentially reducing depression.
Read More
7.5
Reduces stroke risk
1 people found this helpful
Fish oil may improve cardiovascular health by lowering blood pressure and cholesterol, thereby reducing the risk of heart attack and stroke. It can also combat skin aging, enhance skin tone, manage dermatitis, protect against UV radiation, support joint health, and improve nervous system function including memory and cognitive abilities, while strengthening the immune response.
We investigated the impact of docosahexaenoic acid (DHA) on stroke in diabetic mice. Our findings indicate that DHA significantly reduced brain damage and improved neurological functions.
The treatment not only decreased the inflammatory response but also lowered cell death within the brain. We noted remarkable changes in gene expression, suggesting that DHA promotes a protective environment in the brain after a stroke.
Overall, this research highlights DHA's potential as a therapeutic agent for stroke management in diabetic patients.
Read More
9
Omega-3 and COP-1 show promise
Two-phase therapy for improving neuroprotection and neurogenesis: Preventive use of omega fatty acids plus Copolymer-1 immunization after stroke.
We explored the effects of combining omega-3 fatty acids and Copolymer-1 treatment on stroke recovery in a rodent model. The study used a two-phase approach, beginning with omega-3 supplementation followed by COP-1 immunization after a stroke event.
Results indicated that this combination led to significant improvements, including reduced neurological deficits and smaller infarct volumes. There was also a boost in neurogenesis.
These findings suggest a promising avenue for enhanced recovery in stroke patients when integrating dietary and medical strategies.
Read More
9
Omega-3s reduce ischemic stroke risk
Omega-3 Blood Levels and Stroke Risk: A Pooled and Harmonized Analysis of 183 291 Participants From 29 Prospective Studies.
We dove into the connection between omega-3 fatty acids and stroke risks by analyzing data from 29 global cohorts, involving over 183,000 participants.
Our findings revealed that higher levels of omega-3s, particularly eicosapentaenoic acid and docosahexaenoic acid, are linked to a reduced risk of total and ischemic strokes. Specifically, those with the highest omega-3 levels experienced a 17% lower incidence of total stroke and an 18% reduced risk of ischemic stroke.
However, it's important to note that omega-3 levels showed no impact on hemorrhagic stroke risk.
Read More
9
DHA promotes brain recovery post-stroke
Docosahexaenoic acid promotes M2 microglia phenotype via activating PPARγ-mediated ERK/AKT pathway against cerebral ischemia-reperfusion injury.
We investigated the effects of docosahexaenoic acid (DHA), an omega-3 fatty acid, on brain recovery after stroke due to ischemia-reperfusion injuries. In a study involving rats, we discovered that DHA significantly reduced brain damage by shifting microglia from a harmful pro-inflammatory state to a protective anti-inflammatory one.
By promoting M2 microglia and modulating specific signaling pathways, DHA helped in reducing inflammation and supported healing. However, using a PPARγ antagonist inhibited these helpful effects, pointing to the importance of this pathway in DHA’s neuroprotective role.
Read More
9
Docosahexaenoic acid reduces stroke risk
The association between fatty acids and atherosclerotic diseases: A mendelian randomization study.
We examined the link between docosahexaenoic acid (DHA) and stroke incidence through a two-sample mendelian randomization analysis. The study utilized genome-wide association studies to uncover causal relationships at a genetic level.
Our findings indicated that higher levels of DHA are associated with a significantly lower risk of strokes. Specifically, we observed a negative correlation, with an odds ratio of 0.800, suggesting that as DHA levels increase, the likelihood of experiencing a stroke decreases.
This evidence highlights the potential protective effect of DHA against stroke, providing important insights into dietary recommendations and therapeutic targets for reducing stroke risk. It's especially noteworthy that our results showed consistency without signs of heterogeneity, reinforcing the reliability of these findings.
Posh Omega helps reduce "bad" cholesterol, cleansing arteriole walls and lowering blood pressure. This leads to healthier blood viscosity and arterial elasticity, hence protecting against atherosclerosis, coronary heart disease, stroke, and myocardial infarction. My husband and I have been using it for three months, and the benefits are palpable.
Read More
9
Prevents stroke occurrence
Omega-3, an essential fatty acid found in fish oil, is crucial for numerous bodily functions. Due to insufficient dietary intake, supplements are vital. Fish oil enhances blood circulation, prevents arterial hypertension, and supports heart health, reducing the risk of arrhythmia, atherosclerosis, coronary heart disease, myocardial infarction, and stroke. It also aids nerve cell function and can positively affect mood, potentially reducing depression.
Read More
7.5
Reduces stroke risk
1 people found this helpful
Fish oil may improve cardiovascular health by lowering blood pressure and cholesterol, thereby reducing the risk of heart attack and stroke. It can also combat skin aging, enhance skin tone, manage dermatitis, protect against UV radiation, support joint health, and improve nervous system function including memory and cognitive abilities, while strengthening the immune response.
Read More
9
Strengthens stroke prevention
The "SUPER OMEGA" from Carlson Labs contains high-quality Norwegian Omega-3. Daily intake of this product is essential for bodily functions and appearance. It strengthens the heart and blood vessels, lowers blood pressure, and improves circulation, reducing risks of stroke and heart attack. Omega-3 also enhances joint elasticity, alleviating discomfort, and boosts immune response against infections.
Read More
7.5
Improves cholesterol levels
My favourite OMEGA-3 is effective in lowering "bad" cholesterol levels, consequently reducing the risk of vascular atherosclerosis, myocardial infarction, and cerebral stroke.
A stroke occurs when the blood supply to a part of the brain is interrupted or reduced, preventing brain tissue from getting oxygen and nutrients. This can happen in two primary ways: an ischemic stroke, which occurs when a blood vessel supplying blood to the brain is obstructed, often due to a blood clot; and a hemorrhagic stroke, which occurs when a blood vessel in the brain bursts, leading to bleeding in or around the brain. The severity and outcome of a stroke can vary widely depending on the type, location, and amount of brain tissue affected, as well as the speed with which medical treatment is received.
Recognizing the symptoms of a stroke is crucial for prompt treatment and recovery. Common signs include sudden numbness or weakness in the face, arm, or leg, especially on one side of the body, confusion, trouble speaking or understanding speech, vision problems in one or both eyes, and difficulty walking, which may include dizziness or loss of balance coordination. The acronym FAST can help remember the key signs: Face drooping, Arm weakness, Speech difficulty, and Time to call emergency services. If you or someone you know exhibits these symptoms, it's vital to seek immediate medical attention, as timely intervention can significantly improve outcomes.
Omega-3 fish oil is a nutritional supplement derived from the fatty tissues of fish, particularly fatty fish like salmon, mackerel, and sardines. It is rich in omega-3 fatty acids, which are essential fats that the body cannot produce on its own. The most significant types of omega-3s found in fish oil are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), both of which are known for their numerous health benefits. These include reducing inflammation, supporting heart health, and promoting brain function.
Incorporating omega-3 fish oil into your diet can be beneficial if you don’t consume enough fish regularly. Many health experts recommend oily fish as a part of a balanced diet due to their high omega-3 content. For those who find it difficult to include fish in their meals, fish oil supplements can offer a convenient alternative, providing the same essential fatty acids in concentrated form. However, it’s essential to choose high-quality supplements that are third-party tested for purity and potency to avoid contaminants such as heavy metals or other toxins that can impact health.
The potential benefits of Omega-3 fish oil for stroke prevention and recovery have been the subject of various studies, but results can be mixed. Omega-3 fatty acids, which are found in fish oil, are known to have anti-inflammatory properties and can help improve overall heart health. Some research suggests that these fatty acids may reduce the risk of stroke by lowering blood pressure, improving cholesterol levels, and reducing blood clotting tendencies. However, the evidence is not definitive, and more extensive clinical trials are needed to establish a clear connection between Omega-3 intake and stroke prevention.
If you're considering Omega-3 fish oil supplements as part of a strategy to mitigate stroke risk or aid recovery post-stroke, it’s essential to consult with a healthcare provider. They can help you assess your individual risk factors and overall health condition, and discuss appropriate dietary and lifestyle changes alongside any supplements. While Omega-3 fish oil can be part of a healthy diet—especially when combined with other heart-healthy foods—it's not a guaranteed prevention or treatment for strokes. Approaches should be holistic and personalized based on medical advice.
Based on user reviews, the timeline for seeing results from Omega-3 supplements, particularly in relation to stroke prevention, varies but often ranges from a few weeks to several months. For example, one user noted that after three months of taking a product, the benefits became palpable, citing improved cholesterol levels and better heart health (Read Review). Other users have pointed out that regular intake of Omega-3 supplements can enhance circulation, lower blood pressure, and contribute to overall cardiovascular health, although specific timelines for these effects weren't universally detailed in the reviews (Read Review, Read Review).
Most users can expect to start noticing health improvements within a few weeks, but significant changes in cholesterol levels or blood pressure that could correlate with stroke risk reduction might take longer, possibly aligning with longer-term use like in the three-month example provided. Since results can vary depending on individual health status and the specific supplement used, it's advisable to be patient and consult a healthcare provider for personalized recommendations (Read Review).
Research in the field of dietary supplements for stroke prevention reveals several promising findings, particularly regarding omega-3 fatty acids such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). Studies indicate that higher levels of these omega-3s are associated with reduced risks of ischemic strokes. For instance, data from over 183,000 participants show that increased DHA levels correlate with a significant decrease in total and ischemic stroke incidence, with reductions of 12% and 14%, respectively [10]. Moreover, DHA has demonstrated neuroprotective properties, improving recovery outcomes in stroke models by reducing inflammation and neuronal cell death [13].
On the other hand, while eicosapentaenoic acid (EPA) has been associated with lower stroke risk in some studies, its overall impact remains more complex, with mixed evidence regarding its direct benefits [1]. Some research suggests that high levels of EPA may even correlate with an increased risk of ischemic stroke [14]. Overall, while omega-3 fatty acids show potential as beneficial dietary supplements for stroke prevention and recovery, further randomized controlled trials are necessary to solidify their efficacy and understand individual nuances in response to supplementation.
Based on user reviews, many individuals have reported improvements in cardiovascular health and overall well-being after incorporating Omega-3 supplements into their daily regimen. For instance, users noted significant reductions in "bad" cholesterol levels, which contributed to healthier blood viscosity and arterial elasticity, ultimately helping to protect against serious conditions such as atherosclerosis, coronary heart disease, and stroke (Read Review, Read Review, Read Review). Furthermore, several users reported improved blood circulation and lower blood pressure, which are critical factors in reducing heart attack risk (Read Review, Read Review).
Additionally, Omega-3 supplements have shown potential beyond cardiovascular benefits, with some users noting enhancements in skin health, joint flexibility, and even improvements in mood and cognitive function (Read Review, Read Review). While individual results can vary significantly based on factors such as personal health status and supplement quality, the general consensus points towards a range of positive health improvements linked to Omega-3 supplementation.
Users reported significant benefits when combining Omega-3 supplements with other health regimens aimed at mitigating stroke risks. Several reviews highlighted how Omega-3 plays a crucial role in lowering "bad" cholesterol levels and improving blood viscosity, which can enhance vascular health and reduce stroke risk (Read Review, Read Review, Read Review). Users found that along with dietary adjustments, such as increasing fruit and vegetable intake, supplements contributed to improved overall cardiovascular health, including benefits like lower blood pressure and enhanced circulation, which are vital factors in stroke prevention.
Moreover, some users noted that pairing Omega-3 with a healthy lifestyle—including regular exercise and other nutritious supplements—further amplified their health benefits. For instance, the inclusion of Omega-3 in their daily routines was linked to better heart health, joint elasticity, and even enhanced mental clarity (Read Review, Read Review). This combination appears to support a comprehensive approach to cardiovascular health, benefitting not only heart function but also overall well-being.
Based on user reviews, there are several reports regarding the effectiveness of Omega-3 fish oil for treating and preventing stroke. Users have noted that regular supplementation can lead to significant cardiovascular benefits, which include lowering blood pressure, reducing "bad" cholesterol levels, and improving blood circulation. For instance, one user mentions that their use of Omega-3 has helped in the reduction of atherosclerosis and other cardiovascular risks, including stroke Read Review. Another user emphasizes that fish oil is crucial in enhancing blood circulation, thereby supporting overall heart health to mitigate risks associated with stroke Read Review.
While the reviews highlight the general benefits of Omega-3 fish oil, they do not specify an exact dosage for stroke prevention. However, users commonly express that daily intake of a quality Omega-3 supplement is essential for significant benefits, including stroke risk reduction Read Review. Overall, those looking to incorporate Omega-3 for stroke risk management are encouraged to maintain a consistent daily regimen, as this appears to yield the most favorable outcomes according to consumer feedback.
9
Cleanses artery walls
1 people found this helpful
Posh Omega helps reduce "bad" cholesterol, cleansing arteriole walls and lowering blood pressure. This leads to healthier blood viscosity and arterial elasticity, hence protecting against atherosclerosis, coronary heart disease, stroke, and myocardial infarction. My husband and I have been using it for three months, and the benefits are palpable.
7.5
Reduces stroke risk
1 people found this helpful
Fish oil may improve cardiovascular health by lowering blood pressure and cholesterol, thereby reducing the risk of heart attack and stroke. It can also combat skin aging, enhance skin tone, manage dermatitis, protect against UV radiation, support joint health, and improve nervous system function including memory and cognitive abilities, while strengthening the immune response.
9
Strengthens stroke prevention
The "SUPER OMEGA" from Carlson Labs contains high-quality Norwegian Omega-3. Daily intake of this product is essential for bodily functions and appearance. It strengthens the heart and blood vessels, lowers blood pressure, and improves circulation, reducing risks of stroke and heart attack. Omega-3 also enhances joint elasticity, alleviating discomfort, and boosts immune response against infections.
7.5
Improves cholesterol levels
My favourite OMEGA-3 is effective in lowering "bad" cholesterol levels, consequently reducing the risk of vascular atherosclerosis, myocardial infarction, and cerebral stroke.
7.5
Prevents thrombosis effectively
Fish oil effectively lowers blood cholesterol levels and keeps blood unobstructed, thus preventing thrombosis, stroke, and myocardial infarction.
9
Prevents stroke occurrence
Omega-3, an essential fatty acid found in fish oil, is crucial for numerous bodily functions. Due to insufficient dietary intake, supplements are vital. Fish oil enhances blood circulation, prevents arterial hypertension, and supports heart health, reducing the risk of arrhythmia, atherosclerosis, coronary heart disease, myocardial infarction, and stroke. It also aids nerve cell function and can positively affect mood, potentially reducing depression.
9
Omega-3s reduce ischemic stroke risk
Omega-3 Blood Levels and Stroke Risk: A Pooled and Harmonized Analysis of 183 291 Participants From 29 Prospective Studies.
We dove into the connection between omega-3 fatty acids and stroke risks by analyzing data from 29 global cohorts, involving over 183,000 participants.
Our findings revealed that higher levels of omega-3s, particularly eicosapentaenoic acid and docosahexaenoic acid, are linked to a reduced risk of total and ischemic strokes. Specifically, those with the highest omega-3 levels experienced a 17% lower incidence of total stroke and an 18% reduced risk of ischemic stroke.
However, it's important to note that omega-3 levels showed no impact on hemorrhagic stroke risk.
9
DHA promotes brain recovery post-stroke
Docosahexaenoic acid promotes M2 microglia phenotype via activating PPARγ-mediated ERK/AKT pathway against cerebral ischemia-reperfusion injury.
We investigated the effects of docosahexaenoic acid (DHA), an omega-3 fatty acid, on brain recovery after stroke due to ischemia-reperfusion injuries. In a study involving rats, we discovered that DHA significantly reduced brain damage by shifting microglia from a harmful pro-inflammatory state to a protective anti-inflammatory one.
By promoting M2 microglia and modulating specific signaling pathways, DHA helped in reducing inflammation and supported healing. However, using a PPARγ antagonist inhibited these helpful effects, pointing to the importance of this pathway in DHA’s neuroprotective role.
8
Eicosapentaenoic acid and stroke
Exploring Genetic Associations of 3 Types of Risk Factors With Ischemic Stroke: An Integrated Bioinformatics Study.
We explored the connection between eicosapentaenoic acid, a type of omega-3 fatty acid, and the risk of ischemic stroke (IS). The study utilized genetic analysis and data from various sources to determine if eicosapentaenoic acid directly affects stroke outcomes.
Our findings indicated that eicosapentaenoic acid was associated with an increased risk of IS, showing an odds ratio of 2.36. This suggests that higher levels of this fatty acid might correlate with a greater chance of experiencing a stroke.
However, it's important to note that while the results are interesting, they do not clearly establish eicosapentaenoic acid as a beneficial treatment for stroke prevention. Instead, they highlight a potential risk factor that requires further research.
We identified 73 genes associated with blood pressure and circulating lipids in the context of IS, emphasizing the complex interplay between genetics, nutrition, and stroke risk. This study helps advance our understanding of how dietary components may influence stroke dynamics, opening pathways for future investigations.
References
Aggarwal R, Bhatt DL, Steg PG, Miller M, Brinton EA, et al. Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial. J Am Heart Assoc. 2025;14:e038656. doi:10.1161/JAHA.124.038656
Liu C, Guo J, Guan L, Li C, Hu X, et al. Docosahexaenoic acid protects against ischemic stroke in diabetic mice by inhibiting inflammatory responses and apoptosis. Exp Neurol. 2025;385:115075. doi:10.1016/j.expneurol.2024.115075
Cruz-Martínez Y, Cantú K, Ojeda G, Gálvez-Susano V, Arias-Santiago S, et al. Two-phase therapy for improving neuroprotection and neurogenesis: Preventive use of omega fatty acids plus Copolymer-1 immunization after stroke. Brain Res. 2025;1846:149277. doi:10.1016/j.brainres.2024.149277
Xi C, Zhang J, Liu H, Tao S, Xie Y, et al. Can Omega-3 prevent the accidence of stroke: a mendelian randomization study. Hereditas. 2024;161:30. doi:10.1186/s41065-024-00329-9
Chen HC, Tai CJ, Huang JY, Kuo TA, Huang YD, et al. Associations of fish oil with cardiovascular disease events: results from the Taiwan longitudinal study in aging. BMC Public Health. 2024;24:1979. doi:10.1186/s12889-024-19512-8
Miyauchi K, Iwata H, Nishizaki Y, Inoue T, Hirayama A, et al. Randomized Trial for Evaluation in Secondary Prevention Efficacy of Combination Therapy-Statin and Eicosapentaenoic Acid (RESPECT-EPA). Circulation. 2024;150:425. doi:10.1161/CIRCULATIONAHA.123.065520
Burger PM, Bhatt DL, Dorresteijn JAN, Koudstaal S, Mosterd A, et al. Effects of icosapent ethyl according to baseline residual risk in patients with atherosclerotic cardiovascular disease: results from REDUCE-IT. Eur Heart J Cardiovasc Pharmacother. 2024;10:488. doi:10.1093/ehjcvp/pvae030
Liakos CI, Lanaras L, Bristianou M, Papadopoulos DP. Pleiotropic beneficial cardiometabolic actions of a high-purity eicosapentaenoic acid product in high cardiovascular risk individuals. Lipids. 2024;59:67. doi:10.1002/lipd.12391
Gaengler S, Sadlon A, De Godoi Rezende Costa Molino C, Willett WC, Manson JE, et al. Effects of vitamin D, omega-3 and a simple strength exercise programme in cardiovascular disease prevention: The DO-HEALTH randomized controlled trial. J Nutr Health Aging. 2024;28:100037. doi:10.1016/j.jnha.2024.100037
O'Keefe JH, Tintle NL, Harris WS, O'Keefe EL, Sala-Vila A, et al. Omega-3 Blood Levels and Stroke Risk: A Pooled and Harmonized Analysis of 183 291 Participants From 29 Prospective Studies. Stroke. 2024;55:50. doi:10.1161/STROKEAHA.123.044281
Luan M, Wang J, Liang K, Li B, Liu K. Association between the intake of dietary n3 and n6 fatty acids and stroke in US adults: A cross-sectional study of NHANES 2007-2018. PLoS One. 2023;18:e0293893. doi:10.1371/journal.pone.0293893
Ogata S, Manson JE, Kang JH, Buring JE, Lee IM, et al. Marine n-3 Fatty Acids and Prevention of Cardiovascular Disease: A Novel Analysis of the VITAL Trial Using Win Ratio and Hierarchical Composite Outcomes. Nutrients. 2023;15. doi:10.3390/nu15194235
Lv H, Jia S, Sun Y, Pang M, Lv E, et al. Docosahexaenoic acid promotes M2 microglia phenotype via activating PPARγ-mediated ERK/AKT pathway against cerebral ischemia-reperfusion injury. Brain Res Bull. 2023;199:110660. doi:10.1016/j.brainresbull.2023.110660
Liu Y, Wang W, Cui X, Lyu J, Xie Y. Exploring Genetic Associations of 3 Types of Risk Factors With Ischemic Stroke: An Integrated Bioinformatics Study. Stroke. 2024;55:1619. doi:10.1161/STROKEAHA.123.044424
Olshansky B, Bhatt DL, Miller M, Steg PG, Brinton EA, et al. Cardiovascular Benefits of Icosapent Ethyl in Patients With and Without Atrial Fibrillation in REDUCE-IT. J Am Heart Assoc. 2023;12:e026756. doi:10.1161/JAHA.121.026756
Bork CS, Lundbye-Christensen S, Venø SK, Lasota AN, Tjønneland A, et al. Intake of marine and plant-derived n-3 fatty acids and development of atherosclerotic cardiovascular disease in the Danish Diet, Cancer and Health cohort. Eur J Nutr. 2023;62:1389. doi:10.1007/s00394-022-03081-w
Suzuki K, Sato H, Mori H, Matsumoto R, Arimoto Y, et al. Early Enteral Nutrition with High-Protein Whey Peptide Digestive Nutrients May Improve Prognosis in Subarachnoid Hemorrhage Patients. Medicina (Kaunas). 2022;58. doi:10.3390/medicina58091264
Andone S, Farczádi L, Imre S, Bălașa R. Fatty Acids and Lipid Paradox-Neuroprotective Biomarkers in Ischemic Stroke. Int J Mol Sci. 2022;23. doi:10.3390/ijms231810810
Yokoyama Y, Kuno T, Morita SX, Slipczuk L, Takagi H, et al. Eicosapentaenoic Acid for Cardiovascular Events Reduction- Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. J Cardiol. 2022;80:416. doi:10.1016/j.jjcc.2022.07.008
Zhang W, Liu Y, Wu Y, Wang Z, Liu X, et al. ROS-triggered biomimetic hydrogel soft scaffold for ischemic stroke repair. Biomaterials. 2025;319:123217. doi:10.1016/j.biomaterials.2025.123217
Shi F, Chowdhury R, Sofianopoulou E, Koulman A, Sun L, et al. Association of circulating fatty acids with cardiovascular disease risk: analysis of individual-level data in three large prospective cohorts and updated meta-analysis. Eur J Prev Cardiol. 2025;32:233. doi:10.1093/eurjpc/zwae315
Wang Y, Yang B, Wang C. The association between fatty acids and atherosclerotic diseases: A mendelian randomization study. Clin Nutr ESPEN. 2024;63:447. doi:10.1016/j.clnesp.2024.06.018
Ament Z, Patki A, Bhave VM, Kijpaisalratana N, Jones AC, et al. Omega-3 Fatty Acids and Risk of Ischemic Stroke in REGARDS. Transl Stroke Res. 2024. doi:10.1007/s12975-024-01256-7
Kong J, Zou R, Chu R, Hu N, Liu J, et al. An Ultrasmall Cu/CuO Nanoparticle-Based Diselenide-Bridged Nanoplatform Mediating Reactive Oxygen Species Scavenging and Neuronal Membrane Enhancement for Targeted Therapy of Ischemic Stroke. ACS Nano. 2024;18:4140. doi:10.1021/acsnano.3c08734
Yamagata K. Docosahexaenoic acid inhibits ischemic stroke to reduce vascular dementia and Alzheimer's disease. Prostaglandins Other Lipid Mediat. 2023;167:106733. doi:10.1016/j.prostaglandins.2023.106733
Li Y, Zhang M, Li S, Zhang L, Kim J, et al. Selective ischemic-hemisphere targeting Ginkgolide B liposomes with improved solubility and therapeutic efficacy for cerebral ischemia-reperfusion injury. Asian J Pharm Sci. 2023;18:100783. doi:10.1016/j.ajps.2023.100783
Sun E, Zhang J, Deng Y, Wang J, Wu Q, et al. Docosahexaenoic Acid Alleviates Brain Damage by Promoting Mitophagy in Mice with Ischaemic Stroke. Oxid Med Cell Longev. 2022;2022:3119649. doi:10.1155/2022/3119649