We dove into the connection between omega-3 fatty acids and stroke risks by analyzing data from 29 global cohorts, involving over 183,000 participants.
Our findings revealed that higher levels of omega-3s, particularly eicosapentaenoic acid and docosahexaenoic acid, are linked to a reduced risk of total and ischemic strokes. Specifically, those with the highest omega-3 levels experienced a 17% lower incidence of total stroke and an 18% reduced risk of ischemic stroke.
However, it's important to note that omega-3 levels showed no impact on hemorrhagic stroke risk.
Read More
9
DHA reduces stroke damage in mice
Docosahexaenoic acid protects against ischemic stroke in diabetic mice by inhibiting inflammatory responses and apoptosis.
We investigated the impact of docosahexaenoic acid (DHA) on stroke in diabetic mice. Our findings indicate that DHA significantly reduced brain damage and improved neurological functions.
The treatment not only decreased the inflammatory response but also lowered cell death within the brain. We noted remarkable changes in gene expression, suggesting that DHA promotes a protective environment in the brain after a stroke.
Overall, this research highlights DHA's potential as a therapeutic agent for stroke management in diabetic patients.
Read More
9
DHA promotes brain recovery post-stroke
Docosahexaenoic acid promotes M2 microglia phenotype via activating PPARγ-mediated ERK/AKT pathway against cerebral ischemia-reperfusion injury.
We investigated the effects of docosahexaenoic acid (DHA), an omega-3 fatty acid, on brain recovery after stroke due to ischemia-reperfusion injuries. In a study involving rats, we discovered that DHA significantly reduced brain damage by shifting microglia from a harmful pro-inflammatory state to a protective anti-inflammatory one.
By promoting M2 microglia and modulating specific signaling pathways, DHA helped in reducing inflammation and supported healing. However, using a PPARγ antagonist inhibited these helpful effects, pointing to the importance of this pathway in DHA’s neuroprotective role.
Read More
Most Useful Reviews
9
Vessel strengthening
1 people found this helpful
Omega-3 is essential for maintaining elastic blood vessels and preventing health issues like strokes and heart attacks. After experiencing nosebleeds and other symptoms, my doctor advised Omega-3. After a month, my symptoms improved significantly. I will continue to use it and recommend it, especially to women over 50.
Read More
9
Psychological benefits
1 people found this helpful
I find Omega-3 incredibly beneficial, so we take it regularly. It reduces the risk of strokes, supports memory and cognitive function, normalises emotions, and combats fatigue and depression. It also protects the skin and aids in wound healing.
Read More
9
Fatty acid importance
1 people found this helpful
Omega-3 fatty acids are crucial for the proper functioning of the nervous system, heart, and blood vessels. They help combat fatigue, reduce cholesterol, prevent strokes, and maintain mental health. Omega-3 also plays a role in hormone regulation and skin health.
We investigated the impact of docosahexaenoic acid (DHA) on stroke in diabetic mice. Our findings indicate that DHA significantly reduced brain damage and improved neurological functions.
The treatment not only decreased the inflammatory response but also lowered cell death within the brain. We noted remarkable changes in gene expression, suggesting that DHA promotes a protective environment in the brain after a stroke.
Overall, this research highlights DHA's potential as a therapeutic agent for stroke management in diabetic patients.
Read More
9
Omega-3 and COP-1 show promise
Two-phase therapy for improving neuroprotection and neurogenesis: Preventive use of omega fatty acids plus Copolymer-1 immunization after stroke.
We explored the effects of combining omega-3 fatty acids and Copolymer-1 treatment on stroke recovery in a rodent model. The study used a two-phase approach, beginning with omega-3 supplementation followed by COP-1 immunization after a stroke event.
Results indicated that this combination led to significant improvements, including reduced neurological deficits and smaller infarct volumes. There was also a boost in neurogenesis.
These findings suggest a promising avenue for enhanced recovery in stroke patients when integrating dietary and medical strategies.
Read More
9
Omega-3s reduce ischemic stroke risk
Omega-3 Blood Levels and Stroke Risk: A Pooled and Harmonized Analysis of 183 291 Participants From 29 Prospective Studies.
We dove into the connection between omega-3 fatty acids and stroke risks by analyzing data from 29 global cohorts, involving over 183,000 participants.
Our findings revealed that higher levels of omega-3s, particularly eicosapentaenoic acid and docosahexaenoic acid, are linked to a reduced risk of total and ischemic strokes. Specifically, those with the highest omega-3 levels experienced a 17% lower incidence of total stroke and an 18% reduced risk of ischemic stroke.
However, it's important to note that omega-3 levels showed no impact on hemorrhagic stroke risk.
Read More
9
DHA promotes brain recovery post-stroke
Docosahexaenoic acid promotes M2 microglia phenotype via activating PPARγ-mediated ERK/AKT pathway against cerebral ischemia-reperfusion injury.
We investigated the effects of docosahexaenoic acid (DHA), an omega-3 fatty acid, on brain recovery after stroke due to ischemia-reperfusion injuries. In a study involving rats, we discovered that DHA significantly reduced brain damage by shifting microglia from a harmful pro-inflammatory state to a protective anti-inflammatory one.
By promoting M2 microglia and modulating specific signaling pathways, DHA helped in reducing inflammation and supported healing. However, using a PPARγ antagonist inhibited these helpful effects, pointing to the importance of this pathway in DHA’s neuroprotective role.
Read More
9
Docosahexaenoic acid reduces stroke risk
The association between fatty acids and atherosclerotic diseases: A mendelian randomization study.
We examined the link between docosahexaenoic acid (DHA) and stroke incidence through a two-sample mendelian randomization analysis. The study utilized genome-wide association studies to uncover causal relationships at a genetic level.
Our findings indicated that higher levels of DHA are associated with a significantly lower risk of strokes. Specifically, we observed a negative correlation, with an odds ratio of 0.800, suggesting that as DHA levels increase, the likelihood of experiencing a stroke decreases.
This evidence highlights the potential protective effect of DHA against stroke, providing important insights into dietary recommendations and therapeutic targets for reducing stroke risk. It's especially noteworthy that our results showed consistency without signs of heterogeneity, reinforcing the reliability of these findings.
Omega-3 is essential for maintaining elastic blood vessels and preventing health issues like strokes and heart attacks. After experiencing nosebleeds and other symptoms, my doctor advised Omega-3. After a month, my symptoms improved significantly. I will continue to use it and recommend it, especially to women over 50.
Read More
9
Psychological benefits
1 people found this helpful
I find Omega-3 incredibly beneficial, so we take it regularly. It reduces the risk of strokes, supports memory and cognitive function, normalises emotions, and combats fatigue and depression. It also protects the skin and aids in wound healing.
Read More
9
Fatty acid importance
1 people found this helpful
Omega-3 fatty acids are crucial for the proper functioning of the nervous system, heart, and blood vessels. They help combat fatigue, reduce cholesterol, prevent strokes, and maintain mental health. Omega-3 also plays a role in hormone regulation and skin health.
Read More
9
Neurological benefits
Omega-3 fatty acids are vital parts of cell membranes and blood vessels. They're linked to better brain function, reduced depression, and prevention against strokes and vascular diseases. Regular intake is essential for maintaining optimal health.
Read More
9
Supports heart health
Omega 3 is essential for everyone. This manufacturer's fish oil offers high-quality omega that aids joint mobility, alleviates inflammation, enhances hair health, and lowers harmful cholesterol. It actively supports the heart, reducing the risk of stroke and heart attack. With documented benefits, omega is also beneficial for the brain and skin, combating ageing. It is vital for all ages, especially women keen on maintaining their appearance. Take Omega to feel youthful and beautiful!
A stroke occurs when the blood supply to a part of the brain is interrupted or reduced, preventing brain tissue from getting oxygen and nutrients. This can happen in two primary ways: an ischemic stroke, which occurs when a blood vessel supplying blood to the brain is obstructed, often due to a blood clot; and a hemorrhagic stroke, which occurs when a blood vessel in the brain bursts, leading to bleeding in or around the brain. The severity and outcome of a stroke can vary widely depending on the type, location, and amount of brain tissue affected, as well as the speed with which medical treatment is received.
Recognizing the symptoms of a stroke is crucial for prompt treatment and recovery. Common signs include sudden numbness or weakness in the face, arm, or leg, especially on one side of the body, confusion, trouble speaking or understanding speech, vision problems in one or both eyes, and difficulty walking, which may include dizziness or loss of balance coordination. The acronym FAST can help remember the key signs: Face drooping, Arm weakness, Speech difficulty, and Time to call emergency services. If you or someone you know exhibits these symptoms, it's vital to seek immediate medical attention, as timely intervention can significantly improve outcomes.
Omega-3 fish oil is a nutritional supplement derived from the fatty tissues of fish, particularly fatty fish like salmon, mackerel, and sardines. It is rich in omega-3 fatty acids, which are essential fats that the body cannot produce on its own. The most significant types of omega-3s found in fish oil are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), both of which are known for their numerous health benefits. These include reducing inflammation, supporting heart health, and promoting brain function.
Incorporating omega-3 fish oil into your diet can be beneficial if you don’t consume enough fish regularly. Many health experts recommend oily fish as a part of a balanced diet due to their high omega-3 content. For those who find it difficult to include fish in their meals, fish oil supplements can offer a convenient alternative, providing the same essential fatty acids in concentrated form. However, it’s essential to choose high-quality supplements that are third-party tested for purity and potency to avoid contaminants such as heavy metals or other toxins that can impact health.
The potential benefits of Omega-3 fish oil for stroke prevention and recovery have been the subject of various studies, but results can be mixed. Omega-3 fatty acids, which are found in fish oil, are known to have anti-inflammatory properties and can help improve overall heart health. Some research suggests that these fatty acids may reduce the risk of stroke by lowering blood pressure, improving cholesterol levels, and reducing blood clotting tendencies. However, the evidence is not definitive, and more extensive clinical trials are needed to establish a clear connection between Omega-3 intake and stroke prevention.
If you're considering Omega-3 fish oil supplements as part of a strategy to mitigate stroke risk or aid recovery post-stroke, it’s essential to consult with a healthcare provider. They can help you assess your individual risk factors and overall health condition, and discuss appropriate dietary and lifestyle changes alongside any supplements. While Omega-3 fish oil can be part of a healthy diet—especially when combined with other heart-healthy foods—it's not a guaranteed prevention or treatment for strokes. Approaches should be holistic and personalized based on medical advice.
Many users report seeing results from Omega-3 supplements within a month of consistent use. One reviewer mentioned that after taking Omega-3 for a month, their symptoms improved significantly, specifically under a doctor's recommendation for stroke prevention Read Review. Other users emphasize regular intake, suggesting that greater benefits are observed with consistent consumption over time, particularly for cardiovascular health and stroke prevention.
Overall, users tend to highlight the importance of maintaining a routine with Omega-3 supplements to maximize their health benefits, especially concerning heart and blood vessel protection. Many find its effects on heart health and inflammation becoming noticeable fairly quickly, within weeks to a couple of months Read Review. However, as results may vary significantly between individuals, it is always advisable to consult a healthcare professional to tailor the dosage and expectations based on personal health conditions.
Research indicates that certain omega-3 fatty acids, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), may play a significant role in reducing the risk of stroke. Studies have shown that higher levels of EPA are linked to a reduction in both total and ischemic stroke risks; individuals with high EPA levels experienced a 17% lower incidence of total strokes and an 18% reduction in ischemic strokes [10]. Similarly, DHA has demonstrated protective effects against stroke damage and facilitates recovery post-stroke, particularly by reducing inflammation and promoting neuronal health [6].
Moreover, specific treatments that utilize these omega-3s, such as icosapent ethyl, have been shown to lower cardiovascular events, including stroke, in high-risk patients [1]. While there is some mixed evidence regarding the benefits of omega-3 supplementation in stroke prevention, the positive associations suggest that maintaining adequate levels through diet or supplementation could be beneficial, especially for individuals with pre-existing conditions like diabetes [5]. Overall, while further studies are warranted to solidify these findings, omega-3 fatty acids show promise as strategic components in stroke prevention and recovery.
Users have reported a range of positive improvements in their symptoms after incorporating Omega-3 supplements into their daily routines. Many individuals highlight significant benefits for heart health, including lower blood pressure, reduced cholesterol levels, and enhanced blood vessel elasticity. For instance, one reviewer noted a remarkable improvement in their symptoms after a month of Omega-3 supplementation, asserting its effectiveness for stroke prevention under medical guidance Read Review. Others echoed this sentiment, sharing that regular intake led to noticeable reductions in fatigue and better overall emotional well-being Read Review, while some experienced improved energy levels and fewer colds in their families Read Review.
Additionally, users have praised Omega-3 for its role in enhancing cognitive functions, promoting skin health, and mitigating symptoms of depression Read Review. One reviewer remarked on the supplement's efficacy in aiding joint mobility and reducing inflammation, implying benefits that extend beyond cardiovascular health Read Review. While these anecdotal experiences are promising, individual results may vary. Therefore, it's recommended to consult a healthcare professional for tailored advice on supplementation.
Users have reported positive outcomes when combining Omega-3 supplements with other dietary approaches for stroke management. Notably, one reviewer mentioned that incorporating vitamin C alongside Omega-3 may enhance its effects, suggesting a synergistic relationship that could further bolster cardiovascular health and vascular function Read Review. Many users emphasize the importance of Omega-3 in preventing strokes and supporting heart health; they recommend consistent daily intake for optimal results Read Review.
Moreover, some reviews indicate that users have successfully made Omega-3 a part of broader health routines, which include other vitamins or lifestyle changes. For example, one user noted that, despite the size of the capsules being a matter of concern for their parents post-stroke, their neurologist approved Omega-3, underscoring the confidence in its benefits even when combined with other supplementation methods Read Review. Overall, while anecdotal evidence suggests beneficial combinations, users tend to recommend consulting healthcare professionals before making changes to their supplement regimens.
Users report varying perspectives on the optimal dose of Omega-3 fish oil for preventing strokes, but a common recommendation emerges for daily consumption. Several users suggest taking Omega-3 capsules twice daily to maximize benefits. For example, one reviewer noted their family's approach of taking one capsule twice a day to maintain heart health and prevent strokes, highlighting its effectiveness in improving overall wellness and reducing colds among family members Read Review.
Many users emphasize the importance of consulting with healthcare professionals before starting any new supplement regimen, particularly after experiencing health issues like strokes. A user even shared their experience of increasing the concentration of Omega-3 capsules for easier consumption for their parents, underscoring the necessity of adjusting dosage and form based on individual needs Read Review. Ultimately, while users emphasize the significance of Omega-3 for cardiovascular health and stroke prevention, the right dosage may vary based on personal health circumstances and should ideally be discussed with a doctor.
9
Vessel strengthening
1 people found this helpful
Omega-3 is essential for maintaining elastic blood vessels and preventing health issues like strokes and heart attacks. After experiencing nosebleeds and other symptoms, my doctor advised Omega-3. After a month, my symptoms improved significantly. I will continue to use it and recommend it, especially to women over 50.
7.5
Family health
1 people found this helpful
I purchased Omega-3 for my family to maintain heart health, prevent strokes and heart attacks. It has proven effective; I've noticed fewer colds and improved energy in my children. Omega-3 is essential for good health, and the price is reasonable. We take one capsule twice a day.
9
Psychological benefits
1 people found this helpful
I find Omega-3 incredibly beneficial, so we take it regularly. It reduces the risk of strokes, supports memory and cognitive function, normalises emotions, and combats fatigue and depression. It also protects the skin and aids in wound healing.
9
Fatty acid importance
1 people found this helpful
Omega-3 fatty acids are crucial for the proper functioning of the nervous system, heart, and blood vessels. They help combat fatigue, reduce cholesterol, prevent strokes, and maintain mental health. Omega-3 also plays a role in hormone regulation and skin health.
9
Supports heart health
Omega 3 is essential for everyone. This manufacturer's fish oil offers high-quality omega that aids joint mobility, alleviates inflammation, enhances hair health, and lowers harmful cholesterol. It actively supports the heart, reducing the risk of stroke and heart attack. With documented benefits, omega is also beneficial for the brain and skin, combating ageing. It is vital for all ages, especially women keen on maintaining their appearance. Take Omega to feel youthful and beautiful!
7.5
Inflammation relief
1 people found this helpful
Omega-3 enhances blood vessel elasticity and reduces inflammation. It’s great for preventing vascular diseases and is best taken twice daily. I've also heard that vitamin C can enhance Omega's effect. I find the quality of this product very good.
7.5
Easy consumption
1 people found this helpful
Omega-3 capsules are quite large, which presented a challenge for my parents after their strokes. While my father managed, my mother found them too big. Despite the size, my neurologist approved Omega-3, and I've since opted for a higher concentration for easier consumption.
9
Omega-3s reduce ischemic stroke risk
Omega-3 Blood Levels and Stroke Risk: A Pooled and Harmonized Analysis of 183 291 Participants From 29 Prospective Studies.
We dove into the connection between omega-3 fatty acids and stroke risks by analyzing data from 29 global cohorts, involving over 183,000 participants.
Our findings revealed that higher levels of omega-3s, particularly eicosapentaenoic acid and docosahexaenoic acid, are linked to a reduced risk of total and ischemic strokes. Specifically, those with the highest omega-3 levels experienced a 17% lower incidence of total stroke and an 18% reduced risk of ischemic stroke.
However, it's important to note that omega-3 levels showed no impact on hemorrhagic stroke risk.
7
Omega-3 fish oil's effects on stroke limited
Randomized Trial for Evaluation in Secondary Prevention Efficacy of Combination Therapy-Statin and Eicosapentaenoic Acid (RESPECT-EPA).
We aimed to find out how icosapent ethyl, a form of omega-3 fish oil, could help reduce the risk of strokes and other cardiovascular issues in patients with coronary artery disease. Over five years, we studied nearly 4,000 patients, comparing those taking icosapent ethyl with those on standard care.
While we noted a slight decrease in cardiovascular events with icosapent ethyl, the results didn't show strong statistical significance. Additionally, we discovered that while some events were reduced, the treatment also associated with a higher rate of new-onset atrial fibrillation.
7
Omega-3 benefits for heart health
Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial.
We explored the effects of icosapent ethyl, a type of omega-3 fatty acid, on stroke and other cardiovascular events among patients with good control of their cholesterol levels. The analysis came from the REDUCE-IT trial, which involved randomized patients at high cardiovascular risk with elevated triglyceride levels.
Interestingly, we found that icosapent ethyl significantly reduced the occurrence of cardiovascular problems, including stroke, regardless of whether patients had low or high baseline levels of LDL cholesterol. This suggests that even those who manage their cholesterol well can still benefit from this treatment.
7
Fish oil aids stroke prevention in diabetes
Associations of fish oil with cardiovascular disease events: results from the Taiwan longitudinal study in aging.
We examined data from the Taiwan Longitudinal Study in Aging, focusing on 3,652 participants over a span of 12 years. Our goal was to investigate whether fish oil supplements could reduce the risk of stroke.
The results indicated a lower incidence of stroke in those taking fish oil, showing 5.7% compared to 7.7% in non-supplemented individuals. However, significant benefits were mainly observed in diabetic patients, where the adjusted risk for stroke was significantly reduced.
This highlights the potential role of fish oil in stroke prevention, particularly for individuals with diabetes.
References
Aggarwal R, Bhatt DL, Steg PG, Miller M, Brinton EA, et al. Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial. J Am Heart Assoc. 2025;14:e038656. doi:10.1161/JAHA.124.038656
Liu C, Guo J, Guan L, Li C, Hu X, et al. Docosahexaenoic acid protects against ischemic stroke in diabetic mice by inhibiting inflammatory responses and apoptosis. Exp Neurol. 2025;385:115075. doi:10.1016/j.expneurol.2024.115075
Cruz-Martínez Y, Cantú K, Ojeda G, Gálvez-Susano V, Arias-Santiago S, et al. Two-phase therapy for improving neuroprotection and neurogenesis: Preventive use of omega fatty acids plus Copolymer-1 immunization after stroke. Brain Res. 2025;1846:149277. doi:10.1016/j.brainres.2024.149277
Xi C, Zhang J, Liu H, Tao S, Xie Y, et al. Can Omega-3 prevent the accidence of stroke: a mendelian randomization study. Hereditas. 2024;161:30. doi:10.1186/s41065-024-00329-9
Chen HC, Tai CJ, Huang JY, Kuo TA, Huang YD, et al. Associations of fish oil with cardiovascular disease events: results from the Taiwan longitudinal study in aging. BMC Public Health. 2024;24:1979. doi:10.1186/s12889-024-19512-8
Miyauchi K, Iwata H, Nishizaki Y, Inoue T, Hirayama A, et al. Randomized Trial for Evaluation in Secondary Prevention Efficacy of Combination Therapy-Statin and Eicosapentaenoic Acid (RESPECT-EPA). Circulation. 2024;150:425. doi:10.1161/CIRCULATIONAHA.123.065520
Burger PM, Bhatt DL, Dorresteijn JAN, Koudstaal S, Mosterd A, et al. Effects of icosapent ethyl according to baseline residual risk in patients with atherosclerotic cardiovascular disease: results from REDUCE-IT. Eur Heart J Cardiovasc Pharmacother. 2024;10:488. doi:10.1093/ehjcvp/pvae030
Liakos CI, Lanaras L, Bristianou M, Papadopoulos DP. Pleiotropic beneficial cardiometabolic actions of a high-purity eicosapentaenoic acid product in high cardiovascular risk individuals. Lipids. 2024;59:67. doi:10.1002/lipd.12391
Gaengler S, Sadlon A, De Godoi Rezende Costa Molino C, Willett WC, Manson JE, et al. Effects of vitamin D, omega-3 and a simple strength exercise programme in cardiovascular disease prevention: The DO-HEALTH randomized controlled trial. J Nutr Health Aging. 2024;28:100037. doi:10.1016/j.jnha.2024.100037
O'Keefe JH, Tintle NL, Harris WS, O'Keefe EL, Sala-Vila A, et al. Omega-3 Blood Levels and Stroke Risk: A Pooled and Harmonized Analysis of 183 291 Participants From 29 Prospective Studies. Stroke. 2024;55:50. doi:10.1161/STROKEAHA.123.044281
Luan M, Wang J, Liang K, Li B, Liu K. Association between the intake of dietary n3 and n6 fatty acids and stroke in US adults: A cross-sectional study of NHANES 2007-2018. PLoS One. 2023;18:e0293893. doi:10.1371/journal.pone.0293893
Ogata S, Manson JE, Kang JH, Buring JE, Lee IM, et al. Marine n-3 Fatty Acids and Prevention of Cardiovascular Disease: A Novel Analysis of the VITAL Trial Using Win Ratio and Hierarchical Composite Outcomes. Nutrients. 2023;15. doi:10.3390/nu15194235
Lv H, Jia S, Sun Y, Pang M, Lv E, et al. Docosahexaenoic acid promotes M2 microglia phenotype via activating PPARγ-mediated ERK/AKT pathway against cerebral ischemia-reperfusion injury. Brain Res Bull. 2023;199:110660. doi:10.1016/j.brainresbull.2023.110660
Liu Y, Wang W, Cui X, Lyu J, Xie Y. Exploring Genetic Associations of 3 Types of Risk Factors With Ischemic Stroke: An Integrated Bioinformatics Study. Stroke. 2024;55:1619. doi:10.1161/STROKEAHA.123.044424
Olshansky B, Bhatt DL, Miller M, Steg PG, Brinton EA, et al. Cardiovascular Benefits of Icosapent Ethyl in Patients With and Without Atrial Fibrillation in REDUCE-IT. J Am Heart Assoc. 2023;12:e026756. doi:10.1161/JAHA.121.026756
Bork CS, Lundbye-Christensen S, Venø SK, Lasota AN, Tjønneland A, et al. Intake of marine and plant-derived n-3 fatty acids and development of atherosclerotic cardiovascular disease in the Danish Diet, Cancer and Health cohort. Eur J Nutr. 2023;62:1389. doi:10.1007/s00394-022-03081-w
Suzuki K, Sato H, Mori H, Matsumoto R, Arimoto Y, et al. Early Enteral Nutrition with High-Protein Whey Peptide Digestive Nutrients May Improve Prognosis in Subarachnoid Hemorrhage Patients. Medicina (Kaunas). 2022;58. doi:10.3390/medicina58091264
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Yokoyama Y, Kuno T, Morita SX, Slipczuk L, Takagi H, et al. Eicosapentaenoic Acid for Cardiovascular Events Reduction- Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. J Cardiol. 2022;80:416. doi:10.1016/j.jjcc.2022.07.008
Zhang W, Liu Y, Wu Y, Wang Z, Liu X, et al. ROS-triggered biomimetic hydrogel soft scaffold for ischemic stroke repair. Biomaterials. 2025;319:123217. doi:10.1016/j.biomaterials.2025.123217
Shi F, Chowdhury R, Sofianopoulou E, Koulman A, Sun L, et al. Association of circulating fatty acids with cardiovascular disease risk: analysis of individual-level data in three large prospective cohorts and updated meta-analysis. Eur J Prev Cardiol. 2025;32:233. doi:10.1093/eurjpc/zwae315
Wang Y, Yang B, Wang C. The association between fatty acids and atherosclerotic diseases: A mendelian randomization study. Clin Nutr ESPEN. 2024;63:447. doi:10.1016/j.clnesp.2024.06.018
Ament Z, Patki A, Bhave VM, Kijpaisalratana N, Jones AC, et al. Omega-3 Fatty Acids and Risk of Ischemic Stroke in REGARDS. Transl Stroke Res. 2024. doi:10.1007/s12975-024-01256-7
Kong J, Zou R, Chu R, Hu N, Liu J, et al. An Ultrasmall Cu/CuO Nanoparticle-Based Diselenide-Bridged Nanoplatform Mediating Reactive Oxygen Species Scavenging and Neuronal Membrane Enhancement for Targeted Therapy of Ischemic Stroke. ACS Nano. 2024;18:4140. doi:10.1021/acsnano.3c08734
Yamagata K. Docosahexaenoic acid inhibits ischemic stroke to reduce vascular dementia and Alzheimer's disease. Prostaglandins Other Lipid Mediat. 2023;167:106733. doi:10.1016/j.prostaglandins.2023.106733
Li Y, Zhang M, Li S, Zhang L, Kim J, et al. Selective ischemic-hemisphere targeting Ginkgolide B liposomes with improved solubility and therapeutic efficacy for cerebral ischemia-reperfusion injury. Asian J Pharm Sci. 2023;18:100783. doi:10.1016/j.ajps.2023.100783
Sun E, Zhang J, Deng Y, Wang J, Wu Q, et al. Docosahexaenoic Acid Alleviates Brain Damage by Promoting Mitophagy in Mice with Ischaemic Stroke. Oxid Med Cell Longev. 2022;2022:3119649. doi:10.1155/2022/3119649