Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.1
USERS' SCORE
Good
Based on 11 Reviews
8.1
Supplement Facts
Serving Size: 1 Fish Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Cholesterol
<5 mg
1%
Vitamin D3 (as Cholecalciferol) (from Lanolin)
25 mcg (1,000 IU)
125%
Fish Oil Concentrate
1.2 g (1,200 mg)
†
Omega-3 Fatty Acids:
Eicosapentaenoic Acid (EPA)
600 mg
†
Docosahexaenoic Acid (DHA)
300 mg
†
Top Medical Research Studies
9
We dove into the connection between omega-3 fatty acids and stroke risks by analyzing data from 29 global cohorts, involving over 183,000 participants.
Our findings revealed that higher levels of omega-3s, particularly eicosapentaenoic acid and docosahexaenoic acid, are linked to a reduced risk of total and ischemic strokes. Specifically, those with the highest omega-3 levels experienced a 17% lower incidence of total stroke and an 18% reduced risk of ischemic stroke.
However, it's important to note that omega-3 levels showed no impact on hemorrhagic stroke risk.
Our findings revealed that higher levels of omega-3s, particularly eicosapentaenoic acid and docosahexaenoic acid, are linked to a reduced risk of total and ischemic strokes. Specifically, those with the highest omega-3 levels experienced a 17% lower incidence of total stroke and an 18% reduced risk of ischemic stroke.
However, it's important to note that omega-3 levels showed no impact on hemorrhagic stroke risk.
Read More
9
We investigated the impact of docosahexaenoic acid (DHA) on stroke in diabetic mice. Our findings indicate that DHA significantly reduced brain damage and improved neurological functions.
The treatment not only decreased the inflammatory response but also lowered cell death within the brain. We noted remarkable changes in gene expression, suggesting that DHA promotes a protective environment in the brain after a stroke.
Overall, this research highlights DHA's potential as a therapeutic agent for stroke management in diabetic patients.
The treatment not only decreased the inflammatory response but also lowered cell death within the brain. We noted remarkable changes in gene expression, suggesting that DHA promotes a protective environment in the brain after a stroke.
Overall, this research highlights DHA's potential as a therapeutic agent for stroke management in diabetic patients.
Read More
9
We investigated the effects of docosahexaenoic acid (DHA), an omega-3 fatty acid, on brain recovery after stroke due to ischemia-reperfusion injuries. In a study involving rats, we discovered that DHA significantly reduced brain damage by shifting microglia from a harmful pro-inflammatory state to a protective anti-inflammatory one.
By promoting M2 microglia and modulating specific signaling pathways, DHA helped in reducing inflammation and supported healing. However, using a PPARγ antagonist inhibited these helpful effects, pointing to the importance of this pathway in DHA’s neuroprotective role.
By promoting M2 microglia and modulating specific signaling pathways, DHA helped in reducing inflammation and supported healing. However, using a PPARγ antagonist inhibited these helpful effects, pointing to the importance of this pathway in DHA’s neuroprotective role.
Read More
Most Useful Reviews
9
Improves skin condition
9 people found this helpful
An effective product! I recommend it to all! The advantages include improved cardiovascular health (lowering blood pressure, cholesterol, and the risk of heart attack and stroke), aiding skin health (slowing aging, toning, and refreshing its appearance), and supporting joint health (slowing collagen breakdown). It also improves the nervous system, enhancing memory and brain function.
Read More
9
Reduces atherosclerosis risk
1 people found this helpful
Omega-3 fatty acids offer significant cardiovascular health advantages, particularly by lowering triglyceride levels. Elevated triglycerides (hypertriglyceridemia) heighten the risk of atherosclerosis, increasing chances of heart disease and stroke. Thus, managing triglyceride levels is crucial. Omega-3s may also increase HDL (good) cholesterol and help lower blood pressure.
Read More
9
Prevents hypertension
Fish oil expands blood vessels, increasing blood flow to organs and tissues while helping to prevent arterial hypertension. This positively impacts heart function, reducing the risk of arrhythmia, atherosclerosis, coronary heart disease, myocardial infarction, and stroke. Omega-3 is vital for nerve cells and aids in nervous system metabolism, improving nerve impulse conduction. Additionally, it regulates serotonin levels, influencing mood, which helps mitigate depression or shorten its treatment duration.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.1
- All Researches
9
We investigated the impact of docosahexaenoic acid (DHA) on stroke in diabetic mice. Our findings indicate that DHA significantly reduced brain damage and improved neurological functions.
The treatment not only decreased the inflammatory response but also lowered cell death within the brain. We noted remarkable changes in gene expression, suggesting that DHA promotes a protective environment in the brain after a stroke.
Overall, this research highlights DHA's potential as a therapeutic agent for stroke management in diabetic patients.
The treatment not only decreased the inflammatory response but also lowered cell death within the brain. We noted remarkable changes in gene expression, suggesting that DHA promotes a protective environment in the brain after a stroke.
Overall, this research highlights DHA's potential as a therapeutic agent for stroke management in diabetic patients.
Read More
9
We explored the effects of combining omega-3 fatty acids and Copolymer-1 treatment on stroke recovery in a rodent model. The study used a two-phase approach, beginning with omega-3 supplementation followed by COP-1 immunization after a stroke event.
Results indicated that this combination led to significant improvements, including reduced neurological deficits and smaller infarct volumes. There was also a boost in neurogenesis.
These findings suggest a promising avenue for enhanced recovery in stroke patients when integrating dietary and medical strategies.
Results indicated that this combination led to significant improvements, including reduced neurological deficits and smaller infarct volumes. There was also a boost in neurogenesis.
These findings suggest a promising avenue for enhanced recovery in stroke patients when integrating dietary and medical strategies.
Read More
9
We dove into the connection between omega-3 fatty acids and stroke risks by analyzing data from 29 global cohorts, involving over 183,000 participants.
Our findings revealed that higher levels of omega-3s, particularly eicosapentaenoic acid and docosahexaenoic acid, are linked to a reduced risk of total and ischemic strokes. Specifically, those with the highest omega-3 levels experienced a 17% lower incidence of total stroke and an 18% reduced risk of ischemic stroke.
However, it's important to note that omega-3 levels showed no impact on hemorrhagic stroke risk.
Our findings revealed that higher levels of omega-3s, particularly eicosapentaenoic acid and docosahexaenoic acid, are linked to a reduced risk of total and ischemic strokes. Specifically, those with the highest omega-3 levels experienced a 17% lower incidence of total stroke and an 18% reduced risk of ischemic stroke.
However, it's important to note that omega-3 levels showed no impact on hemorrhagic stroke risk.
Read More
9
We investigated the effects of docosahexaenoic acid (DHA), an omega-3 fatty acid, on brain recovery after stroke due to ischemia-reperfusion injuries. In a study involving rats, we discovered that DHA significantly reduced brain damage by shifting microglia from a harmful pro-inflammatory state to a protective anti-inflammatory one.
By promoting M2 microglia and modulating specific signaling pathways, DHA helped in reducing inflammation and supported healing. However, using a PPARγ antagonist inhibited these helpful effects, pointing to the importance of this pathway in DHA’s neuroprotective role.
By promoting M2 microglia and modulating specific signaling pathways, DHA helped in reducing inflammation and supported healing. However, using a PPARγ antagonist inhibited these helpful effects, pointing to the importance of this pathway in DHA’s neuroprotective role.
Read More
8
Icosapent ethyl reduces stroke risk
We explored the effects of icosapent ethyl, a fish oil-derived treatment, on major cardiovascular events in patients with atherosclerotic cardiovascular disease (ASCVD). Over nearly five years, this treatment significantly reduced events like stroke, heart attack, and cardiovascular death, showing effectiveness across all risk levels.
The biggest benefits were observed in those at higher baseline risk, with noticeable reductions in adverse events. Even though icosapent ethyl doesn't eliminate risk completely, it provides valuable protection, especially for the most vulnerable patients.
The biggest benefits were observed in those at higher baseline risk, with noticeable reductions in adverse events. Even though icosapent ethyl doesn't eliminate risk completely, it provides valuable protection, especially for the most vulnerable patients.
Read More
User Reviews
USERS' SCORE
Good
Based on 11 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improves skin condition
9 people found this helpful
An effective product! I recommend it to all! The advantages include improved cardiovascular health (lowering blood pressure, cholesterol, and the risk of heart attack and stroke), aiding skin health (slowing aging, toning, and refreshing its appearance), and supporting joint health (slowing collagen breakdown). It also improves the nervous system, enhancing memory and brain function.
Read More
9
Reduces atherosclerosis risk
1 people found this helpful
Omega-3 fatty acids offer significant cardiovascular health advantages, particularly by lowering triglyceride levels. Elevated triglycerides (hypertriglyceridemia) heighten the risk of atherosclerosis, increasing chances of heart disease and stroke. Thus, managing triglyceride levels is crucial. Omega-3s may also increase HDL (good) cholesterol and help lower blood pressure.
Read More
9
Prevents hypertension
Fish oil expands blood vessels, increasing blood flow to organs and tissues while helping to prevent arterial hypertension. This positively impacts heart function, reducing the risk of arrhythmia, atherosclerosis, coronary heart disease, myocardial infarction, and stroke. Omega-3 is vital for nerve cells and aids in nervous system metabolism, improving nerve impulse conduction. Additionally, it regulates serotonin levels, influencing mood, which helps mitigate depression or shorten its treatment duration.
Read More
7.5
Prevents strokes
Omega with a high content of EPA is aimed at improving heart function while preventing strokes and heart attacks, enhanced by a modest dose of vitamin D.
Read More
7
Lowers cholesterol levels
This Omega-3 product lowers blood cholesterol, effectively preventing cholesterol plaque build-up in vessels, thus combating atherosclerosis. Many of us eventually monitor our vascular health, seeking to minimise heart attack and stroke risks. This high-quality Omega meets GMP standards, which I find essential.
Read More
Frequently Asked Questions
7.5
Improves cholesterol management
I have ordered Omega-3 several times, now for my parents. They have high cholesterol and take Omega-3. I hope it will lower their levels in a month. Personally, as someone with mitral valve prolapse, Omega-3 benefits me, notably reducing the sensation of unwanted strokes.
9
Reduces atherosclerosis risk
1 people found this helpful
Omega-3 fatty acids offer significant cardiovascular health advantages, particularly by lowering triglyceride levels. Elevated triglycerides (hypertriglyceridemia) heighten the risk of atherosclerosis, increasing chances of heart disease and stroke. Thus, managing triglyceride levels is crucial. Omega-3s may also increase HDL (good) cholesterol and help lower blood pressure.
7
Lowers cholesterol levels
This Omega-3 product lowers blood cholesterol, effectively preventing cholesterol plaque build-up in vessels, thus combating atherosclerosis. Many of us eventually monitor our vascular health, seeking to minimise heart attack and stroke risks. This high-quality Omega meets GMP standards, which I find essential.
9
Prevents hypertension
Fish oil expands blood vessels, increasing blood flow to organs and tissues while helping to prevent arterial hypertension. This positively impacts heart function, reducing the risk of arrhythmia, atherosclerosis, coronary heart disease, myocardial infarction, and stroke. Omega-3 is vital for nerve cells and aids in nervous system metabolism, improving nerve impulse conduction. Additionally, it regulates serotonin levels, influencing mood, which helps mitigate depression or shorten its treatment duration.
7.5
Supports joint health
I want to remind you of Omega-3's beneficial properties! It improves vision, skin, and hair conditions, enhances cardiovascular function (lowering pressure and cholesterol, reducing heart attack and stroke risks), and slows skin aging. It also combats various dermatitis types while protecting skin from UV rays, and supports joint health by slowing collagen breakdown and regulating inflammation in joints.
7.5
Prevents strokes
Omega with a high content of EPA is aimed at improving heart function while preventing strokes and heart attacks, enhanced by a modest dose of vitamin D.
7.5
Enhances hormone production
Omega-3s significantly aid in maintaining and improving health by participating in tissue hormone synthesis, crucial for intracellular metabolism. They lower blood cholesterol levels, which decreases heart attack and stroke risks. Omega-3s are vital for nervous system tissues, sperm formation, hormone regulation, including testosterone, and combat psychological stress, depressive conditions, allergies, and autoimmune processes. They enhance memory, concentration, and skin health while lowering cortisol levels, a stress hormone.
7
Omega-3 benefits for heart health
We explored the effects of icosapent ethyl, a type of omega-3 fatty acid, on stroke and other cardiovascular events among patients with good control of their cholesterol levels. The analysis came from the REDUCE-IT trial, which involved randomized patients at high cardiovascular risk with elevated triglyceride levels.
Interestingly, we found that icosapent ethyl significantly reduced the occurrence of cardiovascular problems, including stroke, regardless of whether patients had low or high baseline levels of LDL cholesterol. This suggests that even those who manage their cholesterol well can still benefit from this treatment.
Interestingly, we found that icosapent ethyl significantly reduced the occurrence of cardiovascular problems, including stroke, regardless of whether patients had low or high baseline levels of LDL cholesterol. This suggests that even those who manage their cholesterol well can still benefit from this treatment.
9
We dove into the connection between omega-3 fatty acids and stroke risks by analyzing data from 29 global cohorts, involving over 183,000 participants.
Our findings revealed that higher levels of omega-3s, particularly eicosapentaenoic acid and docosahexaenoic acid, are linked to a reduced risk of total and ischemic strokes. Specifically, those with the highest omega-3 levels experienced a 17% lower incidence of total stroke and an 18% reduced risk of ischemic stroke.
However, it's important to note that omega-3 levels showed no impact on hemorrhagic stroke risk.
Our findings revealed that higher levels of omega-3s, particularly eicosapentaenoic acid and docosahexaenoic acid, are linked to a reduced risk of total and ischemic strokes. Specifically, those with the highest omega-3 levels experienced a 17% lower incidence of total stroke and an 18% reduced risk of ischemic stroke.
However, it's important to note that omega-3 levels showed no impact on hemorrhagic stroke risk.
9
We investigated the impact of docosahexaenoic acid (DHA) on stroke in diabetic mice. Our findings indicate that DHA significantly reduced brain damage and improved neurological functions.
The treatment not only decreased the inflammatory response but also lowered cell death within the brain. We noted remarkable changes in gene expression, suggesting that DHA promotes a protective environment in the brain after a stroke.
Overall, this research highlights DHA's potential as a therapeutic agent for stroke management in diabetic patients.
The treatment not only decreased the inflammatory response but also lowered cell death within the brain. We noted remarkable changes in gene expression, suggesting that DHA promotes a protective environment in the brain after a stroke.
Overall, this research highlights DHA's potential as a therapeutic agent for stroke management in diabetic patients.
9
We investigated the effects of docosahexaenoic acid (DHA), an omega-3 fatty acid, on brain recovery after stroke due to ischemia-reperfusion injuries. In a study involving rats, we discovered that DHA significantly reduced brain damage by shifting microglia from a harmful pro-inflammatory state to a protective anti-inflammatory one.
By promoting M2 microglia and modulating specific signaling pathways, DHA helped in reducing inflammation and supported healing. However, using a PPARγ antagonist inhibited these helpful effects, pointing to the importance of this pathway in DHA’s neuroprotective role.
By promoting M2 microglia and modulating specific signaling pathways, DHA helped in reducing inflammation and supported healing. However, using a PPARγ antagonist inhibited these helpful effects, pointing to the importance of this pathway in DHA’s neuroprotective role.
2
No significant benefits for stroke prevention
We examined the impact of omega-3 fatty acids, vitamin D, and a simple strength exercise program on preventing major cardiovascular events, including strokes, in older adults. Conducted as a randomized, placebo-controlled trial with over 2,100 participants aged 70 and above, this study revealed that these treatments did not significantly lower the risk of stroke or other major cardiovascular events.
While omega-3 led to some changes in lipid levels, the overall results highlighted that these interventions were not effective in preventing serious cardiovascular health issues in this healthy, active population.
While omega-3 led to some changes in lipid levels, the overall results highlighted that these interventions were not effective in preventing serious cardiovascular health issues in this healthy, active population.
References
- Aggarwal R, Bhatt DL, Steg PG, Miller M, Brinton EA, et al. Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial. J Am Heart Assoc. 2025;14:e038656. 10.1161/JAHA.124.038656
- Liu C, Guo J, Guan L, Li C, Hu X, et al. Docosahexaenoic acid protects against ischemic stroke in diabetic mice by inhibiting inflammatory responses and apoptosis. Exp Neurol. 2025;385:115075. 10.1016/j.expneurol.2024.115075
- Cruz-Martínez Y, Cantú K, Ojeda G, Gálvez-Susano V, Arias-Santiago S, et al. Two-phase therapy for improving neuroprotection and neurogenesis: Preventive use of omega fatty acids plus Copolymer-1 immunization after stroke. Brain Res. 2025;1846:149277. 10.1016/j.brainres.2024.149277
- Xi C, Zhang J, Liu H, Tao S, Xie Y, et al. Can Omega-3 prevent the accidence of stroke: a mendelian randomization study. Hereditas. 2024;161:30. 10.1186/s41065-024-00329-9
- Chen HC, Tai CJ, Huang JY, Kuo TA, Huang YD, et al. Associations of fish oil with cardiovascular disease events: results from the Taiwan longitudinal study in aging. BMC Public Health. 2024;24:1979. 10.1186/s12889-024-19512-8
- Miyauchi K, Iwata H, Nishizaki Y, Inoue T, Hirayama A, et al. Randomized Trial for Evaluation in Secondary Prevention Efficacy of Combination Therapy-Statin and Eicosapentaenoic Acid (RESPECT-EPA). Circulation. 2024;150:425. 10.1161/CIRCULATIONAHA.123.065520
- Burger PM, Bhatt DL, Dorresteijn JAN, Koudstaal S, Mosterd A, et al. Effects of icosapent ethyl according to baseline residual risk in patients with atherosclerotic cardiovascular disease: results from REDUCE-IT. Eur Heart J Cardiovasc Pharmacother. 2024;10:488. 10.1093/ehjcvp/pvae030
- Liakos CI, Lanaras L, Bristianou M, Papadopoulos DP. Pleiotropic beneficial cardiometabolic actions of a high-purity eicosapentaenoic acid product in high cardiovascular risk individuals. Lipids. 2024;59:67. 10.1002/lipd.12391
- Gaengler S, Sadlon A, De Godoi Rezende Costa Molino C, Willett WC, Manson JE, et al. Effects of vitamin D, omega-3 and a simple strength exercise programme in cardiovascular disease prevention: The DO-HEALTH randomized controlled trial. J Nutr Health Aging. 2024;28:100037. 10.1016/j.jnha.2024.100037
- O'Keefe JH, Tintle NL, Harris WS, O'Keefe EL, Sala-Vila A, et al. Omega-3 Blood Levels and Stroke Risk: A Pooled and Harmonized Analysis of 183 291 Participants From 29 Prospective Studies. Stroke. 2024;55:50. 10.1161/STROKEAHA.123.044281
- Luan M, Wang J, Liang K, Li B, Liu K. Association between the intake of dietary n3 and n6 fatty acids and stroke in US adults: A cross-sectional study of NHANES 2007-2018. PLoS One. 2023;18:e0293893. 10.1371/journal.pone.0293893
- Ogata S, Manson JE, Kang JH, Buring JE, Lee IM, et al. Marine n-3 Fatty Acids and Prevention of Cardiovascular Disease: A Novel Analysis of the VITAL Trial Using Win Ratio and Hierarchical Composite Outcomes. Nutrients. 2023;15. 10.3390/nu15194235
- Lv H, Jia S, Sun Y, Pang M, Lv E, et al. Docosahexaenoic acid promotes M2 microglia phenotype via activating PPARγ-mediated ERK/AKT pathway against cerebral ischemia-reperfusion injury. Brain Res Bull. 2023;199:110660. 10.1016/j.brainresbull.2023.110660
